DREYFUS TREASURY PRIME CASH MANAGEMENT
24F-2NT, 1994-04-21
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                    DREYFUS TREASURY PRIME CASH MANAGEMENT
                                200 PARK AVENUE
                              NEW YORK, NY  10166


Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, NW
Washington, DC  20549


      24f-2 Notice - DREYFUS TREASURY PRIME CASH MANAGEMENT
      Registration Statement No. 33-25941 - CIK #0000843781

Gentlemen:

    On December 16, 1988, the Registration Statement of Dreyfus Treasury Prime
Cash Management was declared effective by the SEC.  On September 30, 1993,
POst-Effective Amendment No. 6 to the Fund's Registration Statement, offering
Class A and Class B of the Fund, was declared effective by the SEC.  This
Amendment represented the Fund's election to register an indefinite number of
shares of each class and this Notice represents Class A and Class B in the
aggregate for the Fund's Rule 24f-2 filing for the fiscal year ended February
28, 1994.

    The following information is furnished:

    (a) Shares registered under Securities Act
        of 1933 other than pursuant to Rule 24f(2):                None


                                                  SHARES        DOLLAR AMOUNT

    (b) Aggregate shares sold for Class
        A and Class B during fiscal year
        ended 2/28/94 subject to regis-
        tration under Rule 24f-2:         26,126,900,746   $26,126,900,746

    (c) Aggregate shares redeemed for
        Class A and Class B during
        fiscal year ended 2/28/94:        26,678,229,708    26,678,229,708
                                         ----------------   -----------------

     Net Sales During Year [(b) - (c)]     (   551,328,962)  ($   551,328,962)

                                           ================  =================


                              CALCULATION OF FEE

    Since the shares redeemed exceed the shares sold, no registration fee is
required.  An opinion of counsel is enclosed.


                                                 Very truly yours,
MNJ/ems

                                                 Mark N. Jacobs, Secretary
cc:  Mr. J. deMichaelis, SEC
     Ms. R. McLaughlin, E&Y
     Mr. S. Rosenberg, BONY


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