<PAGE> PAGE 1
000 A000000 08/31/95
000 C000000 0000843781
000 D000000 N
000 E000000 NF
000 F000000 Y
000 G000000 N
000 H000000 N
000 I000000 3.0
000 J000000 U
001 A000000 DREYFUS TREASURY PRIME CASH MANAGEMENT
001 B000000 811-5718
001 C000000 2129226754
002 A000000 200 PARK AVENUE
002 B000000 NEW YORK
002 C000000 NY
002 D010000 10166
002 D020000 0144
003 000000 N
004 000000 N
005 000000 N
006 000000 N
007 A000000 N
007 B000000 0
015 A000001 THE BANK OF NEW YORK
015 B000001 C
015 C010001 NEW YORK
015 C020001 NY
015 C030001 10286
015 E010001 X
018 000000 Y
019 A000000 Y
019 B000000 152
019 C000000 DREYFUSFAM
022 A000001 BARCLAYS DE ZOETE WEDD SECURITIES, INC.
022 B000001 13-3551367
022 C000001 2608367
022 D000001 2714414
022 A000002 UBS SECURITIES INC.
022 B000002 13-2932996
022 C000002 878383
022 D000002 401839
022 A000003 HSBC SECURITIES, INC.
022 B000003 13-2650272
022 C000003 679069
022 D000003 377821
022 A000004 EASTBRIDGE CAPITAL INC.
022 B000004 13-3501117
022 C000004 726040
022 D000004 288099
022 A000005 DILLON, READ & CO. INC.
022 B000005 13-1939216
<PAGE> PAGE 2
022 C000005 444469
022 D000005 178206
022 A000006 NESBITT BURNS SECURITIES, INC.
022 B000006 13-2620737
022 C000006 414355
022 D000006 0
022 A000007 AUBREY G. LANSTON & CO. INC.
022 B000007 13-5552129
022 C000007 389670
022 D000007 0
022 A000008 GOLDMAN, SACHS & CO.
022 B000008 13-5108880
022 C000008 312698
022 D000008 0
022 A000009 SMITH BARNEY INC.
022 B000009 13-1912900
022 C000009 299719
022 D000009 0
022 A000010 SANWA SECURITIES USA CO. L.P.
022 B000010 13-3046258
022 C000010 298230
022 D000010 0
023 C000000 7513151
023 D000000 4597455
028 A010000 3311693
028 A020000 6678
028 A030000 0
028 A040000 3353070
028 B010000 3331358
028 B020000 6006
028 B030000 0
028 B040000 3476512
028 C010000 3454631
028 C020000 5831
028 C030000 0
028 C040000 3441825
028 D010000 3501550
028 D020000 5334
028 D030000 0
028 D040000 3369511
028 E010000 3481986
028 E020000 5794
028 E030000 0
028 E040000 3316311
028 F010000 3464134
028 F020000 5788
028 F030000 0
028 F040000 3694778
028 G010000 20545352
028 G020000 35431
028 G030000 0
<PAGE> PAGE 3
028 G040000 20652007
028 H000000 0
042 A000000 1
042 B000000 0
042 C000000 99
042 D000000 0
042 E000000 0
042 F000000 0
042 G000000 0
042 H000000 0
043 000000 202
044 000000 0
049 000000 N
050 000000 N
051 000000 N
052 000000 N
053 A000000 Y
053 B000000 Y
053 C000000 N
054 A000000 Y
054 B000000 Y
054 C000000 Y
054 D000000 N
054 E000000 N
054 F000000 N
054 G000000 Y
054 H000000 N
054 I000000 N
054 J000000 Y
054 K000000 N
054 L000000 Y
054 M000000 Y
054 N000000 N
054 O000000 Y
055 A000000 Y
055 B000000 N
056 000000 N
057 000000 N
059 000000 Y
060 A000000 Y
060 B000000 Y
061 000000 0
062 A000000 Y
062 B000000 102.2
062 C000000 0.0
062 D000000 0.0
062 E000000 0.0
062 F000000 0.0
062 G000000 0.0
062 H000000 0.0
062 I000000 0.0
<PAGE> PAGE 4
062 J000000 0.0
062 K000000 0.0
062 L000000 0.0
062 M000000 0.0
062 N000000 0.0
062 O000000 0.0
062 P000000 0.0
062 Q000000 0.0
062 R000000 0.0
063 A000000 83
063 B000000 0.0
064 A000000 N
064 B000000 N
070 A010000 N
070 A020000 N
070 B010000 N
070 B020000 N
070 C010000 N
070 C020000 N
070 D010000 N
070 D020000 N
070 E010000 N
070 E020000 N
070 F010000 N
070 F020000 N
070 G010000 N
070 G020000 N
070 H010000 N
070 H020000 N
070 I010000 N
070 I020000 N
070 J010000 N
070 J020000 N
070 K010000 N
070 K020000 N
070 L010000 N
070 L020000 N
070 M010000 N
070 M020000 N
070 N010000 N
070 N020000 N
070 O010000 Y
070 O020000 N
070 P010000 Y
070 P020000 N
070 Q010000 N
070 Q020000 N
070 R010000 N
070 R020000 N
071 A000000 0
071 B000000 0
<PAGE> PAGE 5
071 C000000 0
071 D000000 0
072 A000000 6
072 B000000 103675
072 C000000 0
072 D000000 0
072 E000000 0
072 F000000 3488
072 G000000 0
072 H000000 0
072 I000000 0
072 J000000 0
072 K000000 0
072 L000000 0
072 M000000 0
072 N000000 0
072 O000000 0
072 P000000 0
072 Q000000 0
072 R000000 0
072 S000000 0
072 T000000 202
072 U000000 0
072 V000000 0
072 W000000 0
072 X000000 3690
072 Y000000 0
072 Z000000 99985
072AA000000 279
072BB000000 496
072CC010000 0
072CC020000 0
072DD010000 95558
072DD020000 4427
072EE000000 0
073 A010000 0.0289
073 A020000 0.0276
073 B000000 0.0000
073 C000000 0.0000
074 A000000 0
074 B000000 0
074 C000000 3468888
074 D000000 0
074 E000000 0
074 F000000 0
074 G000000 0
074 H000000 0
074 I000000 0
074 J000000 0
074 K000000 0
074 L000000 4876
<PAGE> PAGE 6
074 M000000 0
074 N000000 3473764
074 O000000 0
074 P000000 573
074 Q000000 0
074 R010000 0
074 R020000 0
074 R030000 0
074 R040000 79717
074 S000000 0
074 T000000 3393474
074 U010000 3170846
074 U020000 222852
074 V010000 1.00
074 V020000 1.00
074 W000000 1.0005
074 X000000 1720
074 Y000000 0
075 A000000 3308053
075 B000000 0
076 000000 0.00
077 A000000 N
SIGNATURE JOHN PYBURN
TITLE ASSISTANT TREASURER
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000843781
<NAME> DREYFUS TREASURY PRIME CASH MANAGEMENT
<SERIES>
<NUMBER> 1
<NAME> CLASS A
<MULTIPLIER> 1000
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> FEB-28-1995
<PERIOD-END> AUG-31-1995
<INVESTMENTS-AT-COST> 3468888
<INVESTMENTS-AT-VALUE> 3468888
<RECEIVABLES> 4876
<ASSETS-OTHER> 0
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 3473764
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 80290
<TOTAL-LIABILITIES> 80290
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 3393698
<SHARES-COMMON-STOCK> 3170846
<SHARES-COMMON-PRIOR> 3342399
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (224)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> 3170634
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 103675
<OTHER-INCOME> 0
<EXPENSES-NET> 3690
<NET-INVESTMENT-INCOME> 99985
<REALIZED-GAINS-CURRENT> (217)
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 99768
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (95558)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 19936442
<NUMBER-OF-SHARES-REDEEMED> (20141710)
<SHARES-REINVESTED> 33715
<NET-CHANGE-IN-ASSETS> 71442
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (7)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3488
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 3690
<AVERAGE-NET-ASSETS> 3308053
<PER-SHARE-NAV-BEGIN> 1.000
<PER-SHARE-NII> .029
<PER-SHARE-GAIN-APPREC> 0
<PER-SHARE-DIVIDEND> (.029)
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 1.000
<EXPENSE-RATIO> .002
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0
</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<CIK> 0000843781
<NAME> DREYFUS TREASURY PRIME CASH MANAGEMENT
<SERIES>
<NUMBER> 2
<NAME> CLASS B
<MULTIPLIER> 1000
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> FEB-28-1995
<PERIOD-END> AUG-31-1995
<INVESTMENTS-AT-COST> 3468888
<INVESTMENTS-AT-VALUE> 3468888
<RECEIVABLES> 4876
<ASSETS-OTHER> 0
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 3473764
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> 80290
<TOTAL-LIABILITIES> 80290
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 3393698
<SHARES-COMMON-STOCK> 222852
<SHARES-COMMON-PRIOR> 122523
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (224)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> 0
<NET-ASSETS> 222840
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 103675
<OTHER-INCOME> 0
<EXPENSES-NET> 3690
<NET-INVESTMENT-INCOME> 99985
<REALIZED-GAINS-CURRENT> (217)
<APPREC-INCREASE-CURRENT> 0
<NET-CHANGE-FROM-OPS> 99768
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (4427)
<DISTRIBUTIONS-OF-GAINS> 0
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 608910
<NUMBER-OF-SHARES-REDEEMED> (510297)
<SHARES-REINVESTED> 1716
<NET-CHANGE-IN-ASSETS> 71442
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> (7)
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> 3488
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> 3690
<AVERAGE-NET-ASSETS> 160753
<PER-SHARE-NAV-BEGIN> 1.000
<PER-SHARE-NII> .028
<PER-SHARE-GAIN-APPREC> 0
<PER-SHARE-DIVIDEND> (.028)
<PER-SHARE-DISTRIBUTIONS> 0
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 1.000
<EXPENSE-RATIO> .005
<AVG-DEBT-OUTSTANDING> 0
<AVG-DEBT-PER-SHARE> 0
</TABLE>
