CELL ROBOTICS INTERNATIONAL INC
POS AM, EX-5.1, 2000-12-29
LABORATORY ANALYTICAL INSTRUMENTS
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                                                                    EXHIBIT 5.1

                       [NEUMAN & DRENNEN, LLC LETTERHEAD]



                                December 27, 2000


              Cell Robotics International, Inc.
              2715 Broadbent Parkway N.E.
              Albuquerque, New Mexico 87107

                  RE: S.E.C. REGISTRATION STATEMENT ON FORM SB-2
                      REGISTRATION NO. 33-80347; POST EFFECTIVE AMENDMENT NO. 6
                      REGISTRATION NO. 333-40895; POST EFFECTIVE AMENDMENT NO. 4
                      REGISTRATION NO. 333-55951; POST EFFECTIVE AMENDMENT NO. 1
                      REGISTRATION NO. 333-89225; POST EFFECTIVE AMENDMENT NO. 1

               Ladies and Gentlemen:

                      We have acted as legal counsel for Cell Robotics
              International, Inc. (the "Company") in connection with the
              Company's Post Effective Amendments to the Registration Statements
              on Form SB-2 identified above (the "Registration Statement") filed
              by the Company with the Securities and Exchange Commission under
              the Securities Act of 1933, as amended, and the Prospectus
              included as a part of the Registration Statement (the
              "Prospectus"), relating to 1,757,051 shares of Common Stock of the
              Company (the "Common Stock") and 297,576 Redeemable Common Stock
              Purchase Warrants of the Company (the "Redeemable Warrants"). The
              Common Stock and Redeemable Warrants may be offered and sold by
              the Company and/or by certain selling securityholders of the
              Company in the manner set forth in the Registration Statement and
              Prospectus.

                      In connection therewith, we have examined: (a) the
              Registration Statement and the Prospectus included therein, as
              amended; (b) the Articles of Incorporation and Bylaws of the
              Company; and (c) the relevant corporate proceedings of the
              Company. In addition to such examination we have reviewed such
              other proceedings, documents, and records and have ascertained or
              verified such additional facts as we deem necessary or appropriate
              for purposes of this opinion.

                      Based upon the foregoing, we are of the opinion that:


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                      1.       The Company has been legally incorporated and is
                               validly existing and in good standing under the
                               laws of the State of Colorado.

                      2.       The Common Stock and Redeemable Warrants offered
                               for resale by the selling securityholders have
                               been validly and lawfully issued and are fully
                               paid and nonassessable securities of the Company.
                               The Common Stock and Redeemable Warrants issuable
                               by the Company upon exercise of the
                               Representative Warrants will, upon proper
                               exercise of the Representative Warrants and
                               payment therefor as more fully described in the
                               Registration Statement and Prospectus, be validly
                               and lawfully issued, fully paid and nonassessable
                               securities of the Company. The Common Stock
                               issuable upon exercise of the Redeemable Warrants
                               will, upon proper exercise of the Redeemable
                               Warrants and payment therefor as more fully
                               described in the Registration Statement and
                               Prospectus, be validly and lawfully issued, fully
                               paid and nonassessable securities of the Company.

                      3.       We hereby consent to the filing of this opinion
                               as an exhibit to the Registration Statement and
                               to the reference to our firm under the caption
                               "Legal Matters" in the Prospectus. In giving this
                               consent, we do not admit that we come within the
                               category of persons whose consent is required
                               under Section 7 of the Securities Act of 1933, as
                               amended, or the rules and regulations of the
                               Securities and Exchange Commission thereunder.

                                                       Very truly yours,

                                                       /s/ NEUMAN & DRENNEN, LLC
                                                       Neuman & Drennen, LLC










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