DREYFUS LIFE & ANNUITY INDEX FUND INC
N-30D, 1994-03-09
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PRESIDENT'S LETTER

Dear Shareholder:

  We are pleased to report that for the fiscal year ended  December 31,
1993, the Dreyfus Life and Annuity Index Fund, Inc. produced a total
return of 9.33%.asterisk This performance does not reflect the deduction
of additional charges applicable to separate accounts of participating
insurance companies using the Fund as an underlying investment.
  This closely reflects the performance of the Standard & Poor's 500
Composite Stock Price Index(S&P 500 Index) which produced a total return
of 10.06% during the same twelve month period.2 asterisk The stock
market, as measured by the S&P 500 Index,3 asterisk was in a rising mode
for a good part of the reporting period, which is reflected in the total
return of your Fund. The difference between the Fund's return and that
of the S&P 500 Index results from several factors, including the use of
futures contracts, commissions associated with equity and futures
trading, and other Fund expenses.
  For the most part, economic news during the reporting period was
encouraging. Prices and wages were under little upward pressure.
Interest rates continued to be low by standards of recent years. This
provided a favorable background for higher industrial production and
factory orders. A fairly stable U.S. dollar at reasonable rates of
exchange continued to encourage exports, despite the fact that Japan and
Europe are still gripped by recession. Consumer confidence has improved
and there has been a strong inflow of assets into stocks by individuals
seeking higher returns than they can obtain on bank and money market
instruments. This has encouraged a large increase in the supply of new
issues coming to market. So far, however, demand appears to have kept
pace with supply.
  Although the economy continued to grow at an anemic pace throughout
most of the year, by the 4th quarter it had begun to pick up steam.
Inflation for the most part was not a threat during 1993. However, as
the economy heats up, it could once again become an important factor.

  There are also other aspects of the U.S. economy that bear watching.
Unemployment hovered stubbornly around the 7% level as many of America's
largest companies continued to lay off thousands of employees in an
effort to improve corporate bottom lines. In August, Congress passed the
Budget Reconciliation Act, a combination of tax increases and spending
cuts. The full impact of higher taxes on the economy may not be felt
until the 2nd quarter of 1994.
  As we enter into the Fund's new fiscal year, we remain optimistic for
stock market investments as represented by the Dreyfus Life and Annuity
Index Fund. We look forward to serving your investment needs.

                               Sincerely,
                               Joseph S. DiMartino
                               President

January 19, 1994
New York, N.Y.

asterisk Total return represents the change during the period in a
hypothetical account with dividends reinvested.

2 asterisk SOURCE: LIPPER ANALYTICAL SERVICES, INC. - Reflects the
reinvestment of income dividends and, where applicable, capital gain
distributions.

3 asterisk The Standard & Poor's 500 Composite Stock Price Index is a
widely accepted unmanaged index of stock market performance. "S&P
registered" and "S&P 500 registered" are trademarks of Standard & Poor's
Corporation and have been licensed for use by the Fund.  The Fund is not
sponsored, sold, endorsed or promoted by S&P.


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.            DECEMBER 31, 1993

COMPARISON OF CHANGE IN VALUE OF $10,000 INVESTMENT IN DREYFUS LIFE AND
ANNUITY INDEX FUND, INC.
AND THE STANDARD & POOR'S 500 COMPOSITE STOCK PRICE INDEX
(See exhibit A)
Past performance is not predictive of future performance.
THE FUND'S PERFORMANCE DOES NOT REFLECT THE DEDUCTION OF ADDITIONAL
CHARGES APPLICABLE TO SEPARATE ACCOUNTS OF PARTICIPATING INSURANCE
COMPANIES USING THE FUND AS AN UNDERLYING INVESTMENT.
The above illustration compares a $10,000 investment made in Dreyfus
Life and Annuity Index Fund on 9/29/89 (Inception Date) to a $10,000
investment made in the Standard & Poor's 500 Composite Stock Price Index
on that date. For comparative purposes, the value of the Index on
9/30/89 is used as the beginning value on 9/29/89. All dividends and
capital gain distributions are reinvested.
The Fund's performance takes into account all applicable fees and
expenses. The Standard & Poor's 500 Composite Stock Price Index is a
widely accepted, unmanaged index of overall stock market performance
which does not take into account charges, fees and other expenses.
Further information relating to Fund performance, including expense
reimbursement, if applicable, is contained in the Condensed Financial
Information section of the Prospectus and elsewhere in this report.
asterisk Source: Lipper Analytical Services, Inc.


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
STATEMENT OF INVESTMENTS        DECEMBER 31, 1993

   SHARES       COMMON STOCKS--94.3%                                     VALUE
- -----------                                                            --------
                CAPITAL GOODS--13.7%
      1,840     AMP................................................ $   116,150
      1,580 (a) Advanced Micro Devices.............................      28,045
        911     Alco Standard......................................      49,877
      2,475     Allied-Signal......................................     195,525
      1,990 (a) Amdahl.............................................      11,940
        280 (a) Andrew.............................................      10,780
      2,035     Apple Computer.....................................      59,524
        425     Autodesk...........................................      19,125
      1,475     Black & Decker.....................................      29,131
      5,961     Boeing.............................................     257,813
        250     Briggs & Stratton..................................      20,625
      3,015     Browning-Ferris Industries.........................      77,636
      1,452 (a) COMPAQ Computer....................................     107,448
      1,770     Caterpillar........................................     157,530
        750 (a) Ceridian...........................................      14,250
        590     Cincinnati Milacron................................      12,980
        310 (a) Clark Equipment....................................      16,236
      2,617     Columbia Healthcare................................      87,015
      2,895     Computer Associates International..................     115,800
        300 (a) Computer Sciences..................................      29,850
      2,000     Cooper Industries..................................      98,500
      3,525     Corning............................................      98,700
        450 (a) Cray Research......................................      11,531
        950 (a) DSC Communications.................................      58,425
        540 (a) Data General.......................................       5,063
      1,463     Deere & Co.........................................     108,262
      2,350 (a) Digital Equipment..................................      80,488
      1,000     Dover..............................................      60,750
        985     EG & G.............................................      18,099
        580     E-Systems..........................................      25,158
      1,225     Eaton..............................................      61,863
      3,950     Emerson Electric...................................     237,988
      1,425     Fluor..............................................      57,713
          1 (a) GC Companies.......................................          17
        544     General Dynamics...................................      50,184
     14,921     General Electric...................................   1,564,837
        834     General Signal.....................................      28,669
        595     Giddings & Lewis...................................      15,321
        900     Grainger (W.W.)....................................      51,750
        590     Grumman............................................      23,305
        443     Harnischfeger Industries...........................       9,968
        690     Harris.............................................      31,395
      4,444     Hewlett-Packard....................................     351,075
      2,365     Honeywell..........................................      81,001
      1,970     Illinois Tool Works................................      76,830
      1,840     Ingersoll-Rand.....................................      70,380
      7,279     Intel..............................................     451,297
        835 (a) Intergraph.........................................       8,872
     10,122     International Business Machines....................     571,892
      1,080     Lockheed...........................................      73,710
      1,439     Loral..............................................      54,322
        740 (a) Lotus Development..................................      40,700
        395 (a) M/A-COM............................................       3,407
      1,664     Martin Marietta....................................      74,048
        685     McDonnell Douglas..................................      73,295
        565     Morrison Knudson...................................      14,196
      4,763     Motorola...........................................     439,982
      1,915 (a) National Semiconductor.............................      30,879
      1,281 (a) Navistar International.............................      30,264
      4,380     Northern Telecommunications........................     135,233
        830     Northrop...........................................      31,021
      5,500 (a) Novell.............................................     114,125
      4,977 (a) Oracle Systems.....................................     143,089
      2,025     Pall...............................................      37,209
        845     Parker-Hannifin....................................      31,899
        763     Perkin-Elmer.......................................      29,376
      1,875     Pet................................................      32,813
      2,755     Pitney Bowes.......................................     113,988
        735     Raychem............................................      27,563
      2,385     Raytheon...........................................     157,410
      3,856     Rockwell International.............................     143,154
        660     Scientific-Atlanta.................................      21,780
      1,805 (a) Sun Microsystems...................................      52,571
      1,980 (a) Tandem Computers...................................      21,533
        525     Tektronix..........................................      12,338
      1,583     Texas Instruments..................................     100,521
        330     Thomas & Betts.....................................      19,305
        530     Timken.............................................      17,821
        820     Tyco Laboratories..................................      42,333
      2,845 (a) Unisys.............................................      35,918
        622 (a) Varity.............................................      27,835
      8,448     WMX Technologies...................................     222,816
      6,139     Westinghouse Electric..............................      86,713
      1,818     Xerox..............................................     162,484
        205     Zurn Industries....................................       5,612
                                                                    -----------
                                                                      8,387,876
                                                                    -----------
                CONSUMER BASIC--14.8%
      1,370 (a) ALZA...............................................      38,360
     14,465     Abbott Laboratories................................     426,717
      4,440     Albertson's........................................     118,770
      1,155     Allergan...........................................      26,132
      3,526     American Brands....................................     117,240
      5,415     American Home Products.............................     350,621
      2,390 (a) Amgen..............................................     118,305
      5,855     Archer-Daniels-Midland.............................     133,201
        900     Bard (C.R.)........................................      22,725
      1,036     Bausch & Lomb......................................      53,095
      4,835     Baxter International...............................     117,853
      1,315     Becton Dickinson & Co..............................      47,176
      1,435 (a) Beverly Enterprises................................      19,014
      2,020 (a) Biomet.............................................      20,705
      2,460     Borden.............................................      41,820
      9,080     Bristol-Myers Squibb...............................     527,774
      1,360     Bruno's............................................      12,070
      2,640     CPC Intl...........................................     125,730
      4,405     Campbell Soup......................................     180,605
        970     Clorox.............................................      52,623
      2,723     Colgate-Palmolive..................................     169,847
        745 (a) Community Psychiatric Centers......................      10,430
      4,400     ConAgra............................................     116,050
        650     Fleming Companies..................................      16,088
      2,767     General Mills......................................     168,095
      1,215     Gerber Products....................................      34,476
      1,040     Giant Food.........................................      26,780
        675     Great Atlantic & Pacific Tea.......................      18,225
      4,445     Heinz (H.J.).......................................     159,464
      1,585     Hershey Foods......................................      77,665
     11,443     Johnson & Johnson..................................     512,073
      3,994     Kellogg............................................     226,660
      1,855 (a) Kroger.............................................      37,332
      5,137     Lilly (Eli) & Co...................................     305,009
      1,005     Manor Care.........................................      24,497
      1,005     Medtronic..........................................      82,536
     22,439     Merck & Co.........................................     771,340
        500     Millipore..........................................      20,000
      2,895     National Medical Enterprises.......................      40,530
      5,560     Pfizer.............................................     383,640
     15,348     Philip Morris Companies............................     855,650
      1,577     Pioneer Hi Bred International......................      61,503
        570     Premark International..............................      45,743
     11,943     Procter & Gamble...................................     680,750
      1,184     Quaker Oats........................................      84,064
      1,827     Ralston Purina.....................................      72,623
        850 (a) Ryan's Family Steak House..........................       7,650
        810     St. Jude Medical...................................      21,465
      8,514     Sara Lee...........................................     212,850
      3,363     Schering-Plough....................................     230,366
        400     Shared Medical Systems.............................       9,950
      1,255     Super Valu Stores..................................      45,494
      3,875     Syntex.............................................      61,516
      3,260     Sysco..............................................      95,355
      3,665     UST................................................     101,704
      2,797     Unilever N.V.......................................     323,054
        980     U.S. Surgical......................................      22,050
      3,055     Upjohn.............................................      88,977
      2,360     Warner-Lambert.....................................     159,300
      1,340     Winn-Dixie Stores..................................      71,858
      2,038     Wrigley (Wm.) Jr...................................      89,927
                                                                    -----------
                                                                      9,093,122
                                                                    -----------
                CONSUMER - DISCRETIONARY--15.6%
        500     Alberto-Culver, Cl. B Convertible..................      11,563
      1,249     American Stores....................................      53,707
      4,680     Anheuser-Busch Companies...........................     229,905
      1,260     Avon Products......................................      61,268
        740 (a) Bally Manufacturing................................       6,290
        253     Bassett Furniture..................................       8,855
      3,966     Blockbuster Entertainment..........................     121,459
        490     Brown-Forman.......................................      42,753
        290     Brown Group........................................      10,041
      1,670     Brunswick..........................................      30,060
      1,785     Charming Shoppes...................................      21,197
      6,147     Chrysler...........................................     327,328
     22,723     Coca-Cola..........................................   1,014,012
      1,475     Cooper Tire & Rubber...............................      36,875
        665     Coors (Adolph).....................................      10,806
        655     Cummins Engine.....................................      35,206
        814     Dana...............................................      48,738
      1,255     Dayton-Hudson......................................      83,771
        885     Delta Air Lines....................................      48,343
      1,975     Dillard Department Stores, Cl. A...................      75,050
      9,380     Disney (Walt)......................................     399,823
      5,755     Eastman Kodak......................................     322,280
      1,010     Echlin.............................................      33,583
        315 (a) Fedders............................................       2,008
      8,710     Ford Motor.........................................     561,794
      2,530     Gap (The)..........................................      99,619
     12,438     General Motors.....................................     682,534
        360 (a) Genesco............................................       1,890
      2,180     Genuine Parts......................................      82,023
      3,860     Gillette...........................................     230,153
        445     Goodrich (B.F.)....................................      17,911
      2,613     Goodyear Tire & Rubber.............................     119,545
        535     Handleman..........................................       7,089
      1,335     Harcourt General...................................      48,394
        510 (a) Hartmarx...........................................       3,570
      1,525     Hasbro.............................................      55,281
        834     Hilton Hotels......................................      50,666
        675     International Flavors & Fragrances.................      76,781
        805     Jostens............................................      15,899
      7,140     K mart.............................................     151,725
        645 (a) King World Productions.............................      24,752
      6,365     Limited............................................     109,001
      1,440     Liz Claiborne......................................      32,760
        351     Longs Drug Stores..................................      11,539
      1,275     Lowe's Companies...................................      75,544
        480     Luby's Cafeterias..................................      10,800
      2,052     Marriott...........................................      59,508
      2,374     Mattel.............................................      65,582
      4,360     May Department Stores..............................     171,675
      1,865     Maytag.............................................      33,570
      6,197     McDonald's.........................................     353,229
      1,842     Melville...........................................      74,831
        650     Mercantile Stores..................................      23,563
      1,330     NIKE, Cl. B........................................      61,679
      1,431     Nordstrom..........................................      47,223
        225     Oshkosh B'Gosh.....................................       4,388
        315     Outboard Marine....................................       7,048
        596     PACCAR.............................................      36,505
      4,114     Penney (J.C.)......................................     215,471
      1,070     Pep Boys-Manny Moe & Jack..........................      28,088
     13,891     PepsiCo............................................     567,794
        825     Polaroid...........................................      27,844
      3,802 (a) Price/Costco.......................................      73,189
      1,784 (a) Promus Companies...................................      81,618
      1,505     Reebok International...............................      45,150
      1,535     Rite-Aid...........................................      24,368
      2,800     Rubbermaid.........................................      97,300
        705     Russell............................................      19,916
        220     SPX................................................       3,905
      1,005     Safety-Kleen.......................................      16,331
      6,550     Seagram............................................     171,119
        690 (a) Shoney's...........................................      15,956
        295     Springs Industries.................................      11,136
        880     Stride Rite........................................      14,410
      1,275     TJX................................................      37,134
        500     TRINOVA............................................      15,688
      1,100     Tandy..............................................      54,450
      5,105 (a) Toys R Us..........................................     208,667
        428 (a) UAL................................................      62,488
      1,008 (a) USAir Group........................................      12,978
      1,120     V.F. Corp..........................................      51,660
     40,195     Wal-Mart Stores....................................   1,004,873
      2,145     Walgreen...........................................      87,677
      1,740     Wendy's International..............................      30,233
      1,240     Whirlpool..........................................      82,460
      2,295     Woolworth (F.W.)...................................      58,236
        535     Zenith Electronics.................................       3,745
                                                                    -----------
                                                                      9,566,876
                                                                    -----------
                ENERGY & RELATED--9.4%
      1,618     Amerada Hess.......................................      73,012
      8,713     Amoco..............................................     460,700
      1,042     Ashland Oil........................................      35,558
      2,785     Atlantic Richfield.................................     293,121
      2,455     Baker Hughes.......................................      49,100
      2,265     Burlington Resources...............................      95,979
      5,710     Chevron............................................     497,484
      1,835     Coastal............................................      51,609
      2,411     Dresser Industries.................................      50,028
     21,744     Exxon..............................................   1,369,872
        635     Foster Wheeler.....................................      21,273
      2,006     Halliburton........................................      63,941
        405     Helmerich & Payne..................................      11,289
        846     Kerr-McGee.........................................      38,176
        570     Louisiana Land & Exploration.......................      22,871
        920     McDermott International............................      24,380
      7,010     Mobil..............................................     553,790
        813 (a) NL Industries......................................       3,659
      5,350     Occidental Petroleum...............................      91,619
      1,690     Oryx Energy........................................      29,153
        800     Pennzoil...........................................      42,600
      4,585     Phillips Petroleum.................................     132,965
      1,460 (a) Rowan Companies....................................      13,140
      9,381     Royal Dutch Petroleum..............................     979,142
      1,578     Santa Fe Energy Resources..........................      14,202
      4,255     Schlumberger.......................................     251,577
      1,860     Sun Co.............................................      54,638
      4,535     Texaco.............................................     293,074
      5,030     USX-Marathon Group.................................      82,995
      4,215     Unocal.............................................     117,493
                                                                    -----------
                                                                      5,818,440
                                                                    -----------
                FINANCE--9.5%
      1,980     Aetna Life & Casualty..............................     119,543
      2,055     Ahmanson (H.F.) & Co...............................      40,329
        730     Alexander & Alexander Services.....................      14,235
      8,515     American Express...................................     262,900
      3,790     American General...................................     108,489
      5,567     American International Group.......................     488,503
      5,986     Banc One...........................................     234,202
      1,840     Bank of Boston.....................................      42,320
      6,281     BankAmerica........................................     291,281
      1,445     Bankers Trust NY...................................     114,336
      1,705     Barnett Banks......................................      70,758
        886     Beneficial.........................................      33,890
      1,805     Boatmen's Bancshares...............................      53,924
      1,260     CIGNA..............................................      79,065
      1,085 (a) CNA Financial......................................      84,088
      1,765     Capital Holding....................................      65,526
      3,214     Chase Manhattan....................................     108,874
      4,411     Chemical Banking...................................     176,991
      1,530     Chubb..............................................     119,149
      6,575 (a) Citicorp...........................................     241,631
        975     Continental........................................      26,934
      2,065     CoreStates Financial...............................      53,948
      3,145     Federal Home Loan..................................     156,857
      1,460     First Chicago......................................      63,145
      1,410     First Fidelity Bancorp.............................      64,155
      1,375     First Interstate Bancorp...........................      88,172
      2,950     First Union........................................     121,688
      2,400     Fleet/Norstar Financial Group......................      80,100
      1,480     General Re.........................................     158,360
      1,130     Golden West Financial..............................      44,070
      2,315     Great Western Financial............................      46,300
      1,635     Household International............................      53,342
        895     Jefferson-Pilot....................................      41,953
      1,655     Lincoln National...................................      71,993
      1,120     Mellon Bank........................................      59,360
      3,655     Merrill Lynch & Co.................................     153,510
      3,374     Morgan (J.P.) & Co.................................     234,070
      2,825     NBD Bancorp........................................      83,338
      5,100     Norwest............................................     124,313
      4,095     PNC Financial......................................     118,755
      1,095     SAFECO.............................................      60,225
        740     St. Paul Companies.................................      66,508
      6,142     Sears Roebuck & Co.................................     323,990
      1,635     Shawmut National...................................      35,561
      2,190     SunTrust Banks.....................................      98,550
      1,297     Torchmark..........................................      58,365
      1,370     Transamerica.......................................      77,748
      5,589     Travelers..........................................     217,265
      1,495     USF & G............................................      22,051
        405     USLIFE.............................................      15,542
      1,745     U.S. Bancorp.......................................      43,625
      3,039     Wachovia...........................................     101,807
        967     Wells Fargo........................................     125,106
                                                                    -----------
                                                                      5,840,740
                                                                    -----------
                GENERAL BUSINESS--6.7%
      1,290     American Greetings.................................      43,860
      2,435     Automatic Data Processing..........................     134,534
      1,870     Block (H & R)......................................      76,203
        266     CBS................................................      76,741
        273     Capital Cities/ABC.................................     169,124
      1,670     Circuit City Stores................................      36,323
      2,161 (a) Cisco Systems......................................     139,655
      2,568     Comcast, Cl. A.....................................      92,448
      2,982     Dean Witter Discovery..............................     103,252
      1,455     Deluxe.............................................      52,744
        825     Dial...............................................      33,309
      2,705     Donnelley (R.R.) & Sons............................      84,193
      1,745     Dow Jones & Co.....................................      62,384
      3,075     Dun & Bradstreet...................................     189,496
        970 (a) Federal Express....................................      68,749
      2,580     Gannett............................................     147,705
        555     Harland (John H)...................................      12,002
      2,095     ITT................................................     191,168
      1,325     Interpublic Group Companies........................      42,400
        950     Knight-Ridder......................................      56,763
        796 (a) Litton Industries..................................      51,243
      1,745     MBNA...............................................      58,239
      1,274     Marsh & Mclennan...................................     103,513
        852     McGraw-Hill........................................      57,617
        700     McKesson...........................................      37,800
        265     Meredith...........................................      10,600
      3,755     Minnesota Mining & Manufacturing...................     408,354
        845     Morton International...............................      79,008
        465 (a) National Education.................................       2,906
        860     National Service Industries........................      22,038
      4,733     NationsBank........................................     231,916
      1,840     New York Times, Cl. A..............................      48,300
        940     Rollins Environmental Services.....................       5,405
      1,950     Salomon............................................      92,869
      1,465     Service Corporation International..................      38,456
      1,120     TRW................................................      77,560
      7,867 (a) Tele-Communications, Cl. A.........................     237,976
        980     Teledyne...........................................      25,480
      1,525     Textron............................................      88,831
      6,575     Time Warner........................................     290,943
      2,258     Times Mirror.......................................      75,361
      1,180     Tribune............................................      70,948
      2,170     United Technologies................................     134,540
      1,870     Whitman............................................      30,388
                                                                    -----------
                                                                      4,093,344
                                                                    -----------
                MANUFACTURING--6.3%
        735     ASARCO.............................................      16,813
      2,005     Air Products & Chemicals...........................      88,721
      3,930     Alcan Aluminium....................................      81,548
      1,535     Aluminum Co. of America............................     106,491
      4,981     American Barrick Resources.........................     141,959
      1,584     American Cyanamid..................................      79,596
      1,820 (a) Armco..............................................      10,920
      1,015     Avery Dennison.....................................      29,816
        525     Ball...............................................      15,881
        885     Bemis..............................................      20,908
      1,595 (a) Bethlehem Steel....................................      32,498
      1,535 (a) Crown Cork & Seal..................................      64,278
      1,600     Cyprus Amax Minerals...............................      41,400
      4,789     Dow Chemical.......................................     271,775
     11,865     DuPont (E.I.) de Nemours...........................     572,484
        375     Eastern Enterprises................................       9,563
      1,950     Echo Bay Mines.....................................      25,106
        565     Ecolab.............................................      25,425
      1,677     Engelhard..........................................      40,877
      2,085     Ethyl..............................................      36,488
        640 (a) FMC................................................      30,160
        745     Federal Paper Board................................      15,831
        320     First Mississippi..................................       4,200
      1,630     Grace (W.R.).......................................      66,219
      1,255     Great Lakes Chemical...............................      93,654
        745     Hercules...........................................      84,185
      2,385     Homestake Mining...................................      52,470
      1,340     IMCERA Group.......................................      45,058
      1,915     Inco Ltd...........................................      51,466
        610 (a) Inland Steel Industries............................      20,206
      2,163     International Paper................................     146,543
      1,430     James River........................................      27,528
      2,827     Kimberly-Clark.....................................     146,650
      2,355 (a) Maxus Energy.......................................      12,953
      1,045     Mead...............................................      47,025
      2,100     Monsanto...........................................     154,087
      1,735     Moore..............................................      33,182
        160     NACCO Industries, Cl. A............................       8,240
      1,210     Nalco Chemical.....................................      45,375
        220 (a) National Intergroup................................       2,915
      1,185     Newmont Mining.....................................      68,286
      1,510     Nucor..............................................      80,030
        755     Ogden..............................................      17,176
      1,860     PPG Industries.....................................     141,128
      1,235     Phelps Dodge.......................................      60,206
        700     Pittston...........................................      20,213
      4,175     Placer Dome........................................     103,853
      2,328     Praxair............................................      38,703
      1,040     Reynolds Metals....................................      47,190
      1,180     Rohm & Haas........................................      70,210
      1,285     Scott Paper........................................      52,846
      1,250 (a) Stone Container....................................      12,031
        975     Temple-Inland......................................      49,116
      1,213     USX-US Steel Group.................................      52,614
      1,230     Union Camp.........................................      58,579
      2,645     Union Carbide......................................      59,182
      1,170     Westvaco...........................................      41,681
      1,798     Williams Companies.................................      43,826
      1,588     Worthington Industries.............................      32,544
                                                                    -----------
                                                                      3,849,908
                                                                    -----------
                SHELTER--2.6%
        655     Armstrong World Industries.........................      34,879
        670     Boise Cascade......................................      15,745
        555     Centex.............................................      23,310
      1,620     Champion International.............................      54,068
        530     Crane..............................................      13,118
      4,790     Federal National Mtg. Association..................     376,014
        810     Fleetwood Enterprises..............................      19,238
      1,562     Georgia-Pacific....................................     107,388
      7,836     Home Depot.........................................     309,521
        720     Johnson Controls...................................      38,250
        600     Kaufman & Broad Home...............................      14,250
      1,915     Louisiana-Pacific..................................      78,994
      2,675     Masco..............................................      98,975
      1,390     Newell.............................................      56,121
        740     Owens-Corning Fiberglas............................      32,838
        505     Potlatch...........................................      23,798
        485     Pulte..............................................      17,581
      1,560     Sherwin-Williams...................................      55,770
        165     Skyline............................................       3,259
        745     Snap-On Tools......................................      28,217
        785     Stanley Works......................................      34,933
      3,590     Weyerhaeuser.......................................     160,203
                                                                    -----------
                                                                      1,596,470
                                                                    -----------
                TRANSPORTATION--1.6%
      1,330 (a) AMR................................................      89,110
      1,560     Burlington Northern................................      90,285
      1,815     CSX................................................     147,015
        610 (a) Consolidated Freightways...........................      14,411
      1,405     Consolidated Rail..................................      93,959
      2,435     Norfolk Southern...................................     171,668
        690     Roadway Services...................................      41,400
      1,325     Ryder System.......................................      35,113
      3,204     Santa Fe Pacific...................................      71,289
      3,585     Union Pacific......................................     224,510
        500     Yellow Freight Systems.............................      12,438
                                                                    -----------
                                                                        991,198
                                                                    -----------
                UTILITIES--14.1%
      3,228     American Electric Power............................     119,840
     23,656     American Telephone & Telegraph.....................   1,241,937
      4,765     Ameritech..........................................     365,714
      2,135     Arkla..............................................      16,813
      2,542     Baltimore Gas & Electric...........................      64,503
      7,655     Bell Atlantic......................................     451,645
      8,685     BellSouth..........................................     502,643
      2,805     Carolina Power & Light.............................      84,501
      3,295     Central & South West...............................      99,674
        895 (a) Columbia Gas System................................      20,026
      3,750     Commonwealth Edison................................     105,938
      4,110     Consolidated Edison................................     132,034
      1,615     Consolidated Natural Gas...........................      75,905
      2,585     Detroit Edison.....................................      77,550
      2,935     Dominion Resources.................................     133,176
      3,595     Duke Power.........................................     152,338
      4,200     Enron..............................................     121,800
      1,165     Enserch............................................      18,931
      3,080     Entergy............................................     110,880
      3,290     FPL Group..........................................     128,721
     16,555     GTE................................................     579,425
      2,270     Houston Industries.................................     108,109
      9,385     MCI Communications.................................     265,126
      3,604 (a) McCaw Cellular Communications......................     182,002
        990     NICOR..............................................      27,720
      7,236     NYNEX..............................................     290,345
      2,485     Niagara Mohawk Power...............................      50,321
      1,170     Northern States Power..............................      50,456
        430     ONEOK..............................................       8,116
      2,675     Ohio Edison........................................      60,856
        985     PSI Holdings.......................................      26,103
      1,466     Pacific Enterprises................................      34,818
      7,575     Pacific Gas & Electric.............................     266,072
      7,280     Pacific Telesis Group..............................     393,120
      4,895     PacifiCorp.........................................      94,229
      2,068     Panhandle Eastern..................................      48,857
        605     Peoples Energy.....................................      18,453
      3,868     Philadelphia Electric..............................     117,007
      4,230     Public Service Enterprise Group....................     135,360
      7,835     SCEcorp............................................     156,700
      1,525     Sonat..............................................      44,034
      5,595     Southern...........................................     246,879
     10,480     Southwestern Bell..................................     434,920
      5,950     Sprint.............................................     206,763
      2,952     Tenneco............................................     155,349
      3,900     Texas Utilities....................................     168,675
        705     Transco Energy.....................................       9,958
      1,780     Union Electric.....................................      69,865
      7,695     US West............................................     353,008
                                                                    -----------
                                                                      8,627,215
                                                                    -----------
                TOTAL COMMON STOCKS
                  (cost $53,293,656)............................... $57,865,189
                                                                    ===========

PRINCIPAL
 AMOUNT         SHORT-TERM INVESTMENTS--5.4%                           VALUE
- ----------                                                          -----------
                COMMERICAL PAPER MASTER NOTES--5.0%
                General Electric Credit Corp.,
$3,071,000      3.026%, 01/03/94................................... $ 3,071,000

                U.S. TREASURY BILLS--.4%
   225,000 (b)    3.020%, 03/24/94.................................     223,260
                                                                    -----------
                TOTAL SHORT-TERM INVESTMENTS
                  (cost $3,294,260)................................ $ 3,294,260
                                                                    ===========
TOTAL INVESTMENTS
  (cost $56,587,916)................................      99.7%     $61,159,449
                                                         =====      ===========
CASH AND RECEIVABLES (NET)..........................        .3%     $   159,558
                                                         =====      ===========
TOTAL NET ASSETS.....................................    100.0%     $61,319,007
                                                         =====      ===========
(a) Non-income producing.
(b) Partially held by the custodian in a segregated account as
    collateral for open financial futures position.

<TABLE>
<CAPTION>
DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
STATEMENT OF FINANCIAL FUTURES     DECEMBER 31, 1993

FINANCIAL FUTURES LONG

                                               MARKET VALUE                    UNREALIZED
                                 NUMBER OF     COVERED                         (DEPRECIATION)
ISSUER                           CONTRACTS     BY CONTRACTS     EXPIRATION     AT 12/31/93
- ------                           ---------     ------------     ----------     --------------
<S>                                 <C>        <C>              <C>            <C>
Standard & Poor's 500..........     14         $3,268,650       March '94     ($1,625)
                                                                              ========

</TABLE>
<TABLE>
<CAPTION>
                                 See notes to financial statements

DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
STATEMENT OF ASSETS AND LIABILITIES                                                                   DECEMBER 31, 1993
ASSETS:
  <S>                                                                                    <C>                <C>
  Investments in securities, at value
    (cost $56,587,916)--see statement..............................................                         $61,159,449
  Cash.............................................................................                              42,764
  Receivable for subscriptions to Common Stock.....................................                             199,409
  Dividends and interest receivable................................................                             136,322
  Receivable for investment securities sold........................................                              22,070
  Prepaid expenses.................................................................                              13,235
                                                                                                            -----------
                                                                                                             61,573,249

LIABILITIES:
  Due to The Dreyfus Corporation...................................................      $    6,390
  Due to Wells Fargo Nikko Investment advisors.....................................           6,390
  Payable for investment securities purchased......................................         141,207
  Due to Wells Fargo Institutional Trust Company, N.A..............................          23,035
  Payable for futures variation margin--Note 3(a)..................................          19,600
  Payable for redemptions to Common Stock..........................................              15
  Accrued expenses.................................................................          57,605             254,242
                                                                                         ----------         -----------

NET ASSETS.........................................................................                         $61,319,007
                                                                                                            ===========

REPRESENTED BY:
  Paid-in capital..................................................................                        $57,480,956
  Accumulated distributions in excess of investment income--net....................                            (90,054)
  Accumulated distributions in excess of net realized gain on investments..........                           (641,803)
  Accumulated net unrealized appreciation on investments
    [including $1,625 net unrealized (depreciation) on financial
    futures]--Note 3(b)............................................................                           4,569,908
                                                                                                            -----------

NET ASSETS at value applicable to 4,645,238 shares outstanding (200 million
  shares of $.001 par value Common Stock authorized)...............................                         $61,319,007
                                                                                                            ===========

NET ASSET VALUE, per share
  ($61,319,007 divide 4,645,238 shares)............................................                              $13.20
                                                                                                                 ======

See notes to financial statements.


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
STATEMENT OF OPERATIONS                                                                    YEAR ENDED DECEMBER 31, 1993

INVESTMENT INCOME:
  INCOME:
    Cash dividends (net of foreign taxes witheld at source of $5,887)..............      $1,162,999
    Interest.......................................................................         122,426
                                                                                         ----------
      TOTAL INCOME.................................................................                         $ 1,285,425

  EXPENSES:
    Index management fee--Note 2(a)................................................      $   69,306
    Administration fee--Note 2(a)..................................................          69,306
    Auditing fees..................................................................          57,389
    Custodian fees--Note 2(c)......................................................          44,388
    Directors' fees and expenses--Note 2(d)........................................          19,372
    Organization expenses..........................................................          17,695
    Shareholder servicing costs--Note 2(b).........................................          11,631
    Legal fees.....................................................................           9,480
    Prospectus and shareholders' reports...........................................           6,779
    Miscellaneous..................................................................           5,043
                                                                                         ----------
                                                                                            310,389
    Less--reduction in index management fee and administration fee
      due to undertaking--Note 2(a)................................................         125,566
                                                                                         ----------
      TOTAL EXPENSES...............................................................                             184,823
                                                                                                            -----------
      INVESTMENT INCOME--NET.......................................................                           1,100,602
REALIZED AND UNREALIZED GAIN ON INVESTMENTS:
  Net realized gain on investments--Note 3(a)......................................      $8,399,300
  Net realized gain on financial futures--Note 3(a)................................         113,023
                                                                                         ----------
    NET REALIZED GAIN..............................................................                           8,512,323

  Net unrealized depreciation on investments [including ($6,750) net
    unrealized depreciation on financial futures]..................................                          (5,843,385)
                                                                                                            -----------
      NET REALIZED AND UNREALIZED GAIN ON INVESTMENTS..............................                           2,668,938
                                                                                                            -----------
NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS...............................                         $ 3,769,540
                                                                                                            ===========

See notes to financial statements.


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
STATEMENT OF CHANGES IN NET ASSETS

                                                                                      FOUR MONTHS ENDED    YEAR ENDED
                                                                                      DECEMBER 31,         DECEMBER 31,
                                                                                      1992                 1993
                                                                                      -----------------    -------------
OPERATIONS:
  Investment income-net...........................................................    $   636,808          $ 1,100,602
  Net realized gain on investments................................................      2,914,710            8,512,323
  Net unrealized appreciation (depreciation) on investments for the year..........        898,217           (5,843,385)
                                                                                      -----------          -----------
    NET INCREASE IN NET ASSETS RESULTING FROM OPERATIONS..........................      4,449,735            3,769,540
                                                                                      -----------          -----------

DIVIDENDS TO SHAREHOLDERS FROM:
  Investment income-net...........................................................     (1,011,624)          (1,029,496)
  Excess investment income-net....................................................          --                 (90,054)
  Net realized gain on investments................................................     (1,074,591)         (11,029,996)
  Excess net realized gain on investments.........................................          --                (641,803)
                                                                                      -----------          -----------
    TOTAL DIVIDENDS..............................................................      (2,086,215)         (12,791,349)
                                                                                      -----------          -----------

CAPITAL STOCK TRANSACTIONS:
  Net proceeds from shares sold..................................................       9,341,690           40,165,929
  Dividends reinvested...........................................................         105,760           14,046,814
  Cost of shares redeemed........................................................     (16,185,227)         (53,943,720)
                                                                                      -----------          -----------
    INCREASE (DECREASE) IN NET ASSETS FROM CAPITAL STOCK TRANSACTIONS............      (6,737,777)             269,023
                                                                                      -----------          -----------
      TOTAL (DECREASE) IN NET ASSETS.............................................      (4,374,257)          (8,752,786)

NET ASSETS:
  Beginning of year..............................................................      74,446,050           70,071,793
                                                                                      -----------          -----------
  End of year (including distributions in excess of investment
    income-net; ($71,106) in 1992 and ($90,054) in 1993).........................     $70,071,793          $61,319,007
                                                                                      ===========          ===========

                                                                                         SHARES               SHARES
                                                                                      -----------          -----------
CAPITAL SHARE TRANSACTIONS:
  Shares sold....................................................................         613,493            2,578,683
  Shares issued for dividends reinvested.........................................           7,103            1,010,623
  Shares redeemed................................................................      (1,055,946)          (3,516,794)
                                                                                      -----------          -----------
    NET INCREASE (DECREASE) IN SHARES OUTSTANDING................................        (435,350)              72,512
                                                                                      ===========          ===========

See notes to financial statements.
</TABLE>

DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
FINANCIAL HIGHLIGHTS

    Contained below is per share operating performance data for a share
of Common Stock outstanding, total investment return, ratios to average
net assets and other supplemental data for each year indicated. This
information has been derived from information provided in the Fund's
financial statements.
<TABLE>
<CAPTION>
                                                                                               FOUR MONTHS
                                                                    YEAR ENDED AUGUST 31,        ENDED      YEAR ENDED
                                                              ------------------------------   DECEMBER 31, DECEMBER 31,
                                                              1990(1)     1991        1992        1992         1993
                                                              ------      ------      ------      ------       ------
PER SHARE DATA:
  <S>                                                         <C>         <C>         <C>         <C>          <C>
  Net asset value, beginning of year......................    $12.50      $11.62      $14.20      $14.87       $15.32
                                                              ------      ------      ------      ------       ------

  INVESTMENT OPERATIONS:

  Investment income-net...................................       .38         .39         .37         .13          .37
  Net realized and unrealized gain (loss) on investments..      (.95)       2.60         .68         .77         1.04
                                                              ------      ------      ------      ------       ------
     TOTAL FROM INVESTMENT OPERATIONS.....................      (.57)       2.99        1.05         .90         1.41
                                                              ------      ------      ------      ------       ------
  DISTRIBUTIONS:

  Dividends from investment income-net....................      (.31)       (.39)       (.38)       (.21)        (.37)
  Dividends from net realized gain on investments.........        --        (.02)        --         (.24)       (3.00)
   Excess dividends from net realized gain on investments.        --         --          --          --          (.16)
                                                              ------      ------      ------      ------       ------
     TOTAL DISTRIBUTIONS..................................      (.31)       (.41)       (.38)       (.45)       (3.53)
                                                              ------      ------      ------      ------       ------
  Net asset value, end of year............................    $11.62      $14.20      $14.87      $15.32       $13.20
                                                              ======      ======      ======      ======       ======
TOTAL INVESTMENT RETURN...................................     (4.73%)(2)  26.26%       7.49%       6.05%(2)     9.33%
RATIOS/SUPPLEMENTAL DATA:

  Ratio of expenses to average net assets.................       .37%(2)     .40%        .40%        .13%(2)      .40%

  Ratio of net investment income to average net assets....      3.12%(2)    3.05%       2.63%        .85%(2)     2.38%

  Decrease reflected in above expense ratios due to
     undertakings by WFNIA and Dreyfus....................       .17%(2)     .11%        .13%        .03%(2)      .27%

  Portfolio Turnover Rate.................................       .99%(2)    1.02%       7.66%       6.94%(2)    71.71%

  Net Assets, end of year (000's Omitted).................   $48,184     $62,400     $74,446     $70,072      $61,319

- ----------------------
(1) From September 29, 1989 (commencement of operations) to
    August 31, 1990.
(2) Not annualized.

See notes to financial statements.
</TABLE>

DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
NOTES TO FINANCIAL STATEMENTS

NOTE 1--SIGNIFICANT ACCOUNTING POLICIES:
  The Fund is registered under the Investment Company Act of 1940
("Act") as a non-diversified open-end management investment company.
Wells Fargo Nikko Investment Advisors ("WFNIA") serves as the Fund's
index manager. Wells Fargo Investment Advisors ("WFIA"), the predecessor
index manager of the Fund, and The Nikko Securities Co., Ltd. and an
affiliate ("Nikko") each own 50% of WFNIA. Wells Fargo Institutional
Trust Company, N.A. ("WFITC"), an affiliate of WFNIA, is the custodian
of the Fund's investments. The Dreyfus Corporation ("Dreyfus") serves as
the Fund's administrator. Dreyfus Service Corporation ("Distributor"), a
wholly-owned subsidiary of Dreyfus, acts as the exclusive distributor of
the Fund's shares, which are sold without a sales charge.

  (A) PORTFOLIO VALUATION: Investments in securities are valued at the
last sales price on the securities exchange on which such securities are
primarily traded or at the last sales price on the national securities
market. Securities not listed on an exchange or the national securities
market, or securities for which there were no transactions, are valued
at the average of the most recent bid and asked prices. Bid price is
used when no asked price is available. Short-term investments are
carried at amortized cost, which approximates value. Investments traded
in foreign currencies are translated to U.S. dollars at the prevailing
rates of exchange.

  (B) SECURITIES TRANSACTIONS AND INVESTMENT INCOME: Securities
transactions are recorded on a trade date basis. Realized gain and loss
from securities transactions are recorded on the identified cost basis.
Dividend income is recognized on the ex-dividend date and interest
income, including, where applicable, amortization of discount on
investments, is recognized on the accrual basis.

  (C) DIVIDENDS TO SHAREHOLDERS: Dividends are recorded on the ex-
dividend date. Dividends from investment income-net are declared and
paid on a quarterly basis. Dividends from net realized capital gain are
normally declared and paid annually, but the Fund may make distributions
on a more frequent basis to comply with the distribution requirements of
the Internal Revenue Code. This may result in distributions that are in
excess of net realized gains on a fiscal year basis. To the extent that
net realized capital gain can be offset by capital loss carryovers, if
any, it is the policy of the Fund not to distribute such gain.

  Dividends in excess of investment income net and net realized gain for
financial statement purposes result from Federal income tax distribution
requirements, primarily losses from security transactions incurred in
prior years.

  (D) FEDERAL INCOME TAXES: It is the policy of the Fund to continue to
qualify as a regulated investment company, if such qualification is in
the best interests of its shareholders, by complying with the provisions
available to certain investment companies, as defined in applicable
sections of the Internal Revenue Code, and to make distributions of
taxable income sufficient to relieve it from all, or substantially all,
Federal income taxes.

NOTE 2--MANAGEMENT FEE, ADMINISTRATION FEE AND OTHER TRANSACTIONS WITH
AFFILIATES:

  (A) Fees paid by the Fund pursuant to the provisions of an Index
Management Agreement with WFNIA and an Administration Agreement with
Dreyfus are payable monthly. WFNIA and Dreyfus each receive annual fees
of .15 of 1% of the average daily value of the Fund's net assets. The
agreements further provide that if in any full year the aggregate
expenses of the Fund, exclusive of interest, taxes, brokerage and
extraordinary expenses, exceed the expense limitation of any state
having jurisdiction over the Fund, the Fund may deduct from the fees to
be paid to each of WFNIA and Dreyfus, or WFNIA and Dreyfus will each
bear 50% of such excess expenses. The most stringent state expense
limitation applicable to the Fund presently requires reimbursement of
expenses in any full year that such expenses exceed 2-1/2% of the first
$30 million, 2% of the next $70 million and 1-1/2% of the excess over
$100 million of the average value of the Fund's net assets in accordance
with California "blue sky" regulations. However, WFNIA and Dreyfus have
currently undertaken from January 1, 1993 until December 31, 1993 and
thereafter until such a time as they give shareholders at least 180 days
notice to the contrary that if the Fund's aggregate expenses (exclusive
of brokerage commissions, transaction fees and extraordinary expenses)
exceed an annual rate of .40 of 1% of the average daily value of the
Fund's net assets, the Fund may deduct from the payments to be made to
WFNIA and Dreyfus, or WFNIA and Dreyfus will bear, such excess expense.
Pursuant to undertakings, WFNIA and Dreyfus reduced the index management
fee and the administration fee for the year ended December 31, 1993
62,783 each.

  (B) Pursuant to the Fund's Shareholder Services Plan, the Fund
reimburses the Distributor an amount not to exceed an annual rate of .25
of 1% of the Value of the Fund's average daily net assets for servicing
shareholder accounts. The services provided may include personal
services relating to shareholder accounts, such as answering shareholder
inquiries regarding the Fund and providing reports and other
information, and services related to the maintenance of shareholder
accounts. During the year ended December 31, 1993, the Fund was charged
an aggregate of $508 pursuant to the Shareholder Services Plan.

  (C) During the year ended December 31, 1993, Wells Fargo Institutional
Trust Company, N.A. earned $44,388 for custodian services provided to
the Fund.

  (D) Certain officers and directors of the Fund are "affiliated
persons," as defined in the Act, of Dreyfus. Each director who is not an
"affiliated person" receives an annual fee of $2,500 and an attendance
fee of $500 per meeting.

  (E) On December 5, 1993, Dreyfus entered into an Agreement and Plan of
Merger providing for the merger of Dreyfus with a subsidiary of Mellon
Bank Corporation ("Mellon").

  Upon closing of the merger, it is planned that Dreyfus will retain its
New York headquarters and will be a separate subsidiary within the
Mellon organization. It is expected that the Dreyfus' management team
and mutual fund managers will remain in place, and the Dreyfus mutual
funds will be operated in the same manner as they are currently.

  Following the merger, Dreyfus will be either a direct or indirect
subsidiary of Mellon, whose principal banking subsidiary is Mellon Bank,
N.A. Closing of this merger is subject to a number of contingencies,
including the receipt of certain regulatory approvals and the approvals
of the stockholders of Dreyfus and of Mellon. The merger is expected to
occur in mid-1994, but could occur later.

NOTE 3--SECURITIES TRANSACTIONS:

  (A) The aggregate amount of purchases and sales of investment
securities, other than short-term securities, for the year ended
December 31, 1993 amounted to $31,318,067 and $42,988,046, respectively.

  The Fund is engaged in trading financial futures contracts. The Fund
is exposed to market risk as a result of changes in the value of the
underlying financial instruments (see Statement of Financial Futures).
Investments in financial futures require the Fund to "mark to market" on
a daily basis, which reflects the change in the market value of the
contract at the close of each day's trading. Accordingly, variation
margin payments are made or received to reflect daily unrealized gains
or losses. When the contracts are closed, the Fund recognizes a realized
gain or loss. These investments require initial margin deposits with a
custodian, which consist of cash or cash equivalents, up to
approximately 10% of the Contract amount. The amount of these deposits
is determined by the exchange or Board of Trade on which the contract is
traded and is subject to change.

  (B) At December 31, 1993, accumulated net unrealized appreciation on
investments was $4,569,908, consisting of $5,981,076, gross unrealized
appreciation and $1,411,168 gross unrealized depreciation.

  At December 31, 1993, the costs of investments for Federal income tax
purposes was substantially the same as the cost for financial reporting
purposes (see the Statement of Investments).


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
REPORT OF INDEPENDENT ACCOUNTANTS

TO THE SHAREHOLDERS AND BOARD OF DIRECTORS OF
DREYFUS LIFE AND ANNUITY INDEX FUND, INC.:

  We have audited the accompanying statement of assets and liabilities
of the Dreyfus Life and Annuity Index Fund, Inc. (the Fund), including
the statements of investments and financial futures, as of December 31,
1993, and the related statement of operations for the year then ended,
the statements of changes in net assets for the year then ended and for
the period September 1, 1992 to December 31, 1992, and the financial
highlights for the year then ended, for the period September 1, 1992 to
December 31, 1992, the years ended August 31, 1992 and 1991, and for the
period September 29, 1989 (commencement of operations) to August 31,
1990. These financial statements and financial highlights are the
responsibility of the Fund's management. Our responsibility is to
express an opinion on these financial statements and financial
highlights based on our audits.

  We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to
obtain reasonable assurance about whether the financial statements and
financial highlights are free of material misstatement. An audit
includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements. Our procedures included
confirmation of securities owned as of December 31, 1993, by
correspondence with the custodian and brokers. An audit also includes
assessing the accounting principles used and significant estimates made
by management, as well as evaluating the overall financial statement
presentation. We believe that our audits provide a reasonable basis for
our opinion.

  In our opinion, the financial statements and financial highlights
referred to above present fairly, in all material respects, the
financial position of the Dreyfus Life and Annuity Index Fund, Inc. as
of December 31, 1993, the results of its operations for the year then
ended, the changes in its net assets for the year then ended and for the
period from September 1, 1992 to December 31, 1992, and the financial
highlights for the year then ended, for the period from September 1,
1992 to December 31, 1992, for the years ended August 31, 1992 and 1991,
and for the period September 29, 1989 (commencement of operations) to
August 31, 1990, in conformity with generally accepted accounting
principles.

                                    COOPERS & LYBRAND
New York, New York
February 10, 1994


DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
IMPORTANT TAX INFORMATION (UNAUDITED)

  For Federal Tax purposes the Fund hereby designates $.945 per share as
long-term capital gain distribution of the $.960 per share paid on
September 1, 1993. The Fund also designates $2.175 per share as a long-
term capital gain distribution of the $2.29 per share paid on December
31, 1993.



DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
144 Glenn Curtiss Boulevard
Uniondale, NY 11556

INDEX FUND MANAGER
Wells Fargo Nikko
Investment Advisors
45 Fremont Street
San Francisco, CA 94105

ADMINISTRATOR
The Dreyfus Corporation
200 Park Avenue
New York, NY 10166

DISTRIBUTOR
Dreyfus Service Corporation
200 Park Avenue
New York, NY 10166

CUSTODIAN
Wells Fargo Institutional Trust Company, N.A.
45 Fremont Street
San Francisco, CA 94105

TRANSFER AGENT &
DIVIDEND DISBURSING AGENT
The Shareholder Services Group, Inc.
P.O. Box 9671
Providence, RI 02940
Further information is contained in the Prospectus,
which must precede or accompany this report.
Printed in U.S.A.                  763AR9312

Life and
Annuity
Index Fund, Inc.
Annual Report

December 31, 1993

(Dreyfus Lion Logo)







   COMPARISON OF CHANGE IN VALUE OF $10,000 INVESTMENT
   IN DREYFUS LIFE AND ANNUITY INDEX FUND, INC.
   AND THE STANDARD & POOR'S 500 COMPOSITE STOCK PRICE
   INDEX
   EXHIBIT A:
   ____________________________________________________________________
 |              |       STANDARD        |                         |
 |              |     & POOR'S 500      |         DREYFUS         |
 |  PERIOD      |    COMPOSITE STOCK    |    LIFE AND ANNUNITY    |
 |              |     PRICE INDEX *     |       INDEX FUND        |
 | ---------    |    ---------------    |    -----------------    |
 |  9/29/89     |            10,000     |              10,000     |
 |  9/30/89     |            10,000     |              10,000     |
 | 10/31/89     |             9,768     |               9,784     |
 | 11/30/89     |             9,966     |               9,976     |
 | 12/31/89     |            10,205     |              10,216     |
 |  1/31/90     |             9,521     |               9,530     |
 |  2/28/90     |             9,644     |               9,643     |
 |  3/31/90     |             9,899     |               9,901     |
 |  4/30/90     |             9,653     |               9,649     |
 |  5/31/90     |            10,592     |              10,577     |
 |  6/30/90     |            10,521     |              10,503     |
 |  7/31/90     |            10,487     |              10,470     |
 |  8/31/90     |             9,540     |               9,527     |
 |  9/30/90     |             9,077     |               9,068     |
 | 10/31/90     |             9,038     |               9,029     |
 | 11/30/90     |             9,621     |               9,599     |
 | 12/31/90     |             9,889     |               9,860     |
 |  1/31/91     |            10,318     |              10,286     |
 |  2/28/91     |            11,055     |              11,013     |
 |  3/31/91     |            11,322     |              11,280     |
 |  4/30/91     |            11,349     |              11,294     |
 |  5/31/91     |            11,837     |              11,773     |
 |  6/30/91     |            11,295     |              11,243     |
 |  7/31/91     |            11,822     |              11,758     |
 |  8/31/91     |            12,101     |              12,030     |
 |  9/30/91     |            11,899     |              11,826     |
 | 10/31/91     |            12,058     |              11,984     |
 | 11/30/91     |            11,573     |              11,498     |
 | 12/31/91     |            12,895     |              12,803     |
 |  1/31/92     |            12,655     |              12,562     |
 |  2/29/92     |            12,820     |              12,717     |
 |  3/31/92     |            12,571     |              12,468     |
 |  4/30/92     |            12,939     |              12,826     |
 |  5/31/92     |            13,003     |              12,878     |
 |  6/30/92     |            12,809     |              12,688     |
 |  7/31/92     |            13,331     |              13,200     |
 |  8/31/92     |            13,060     |              12,930     |
 |  9/30/92     |            13,214     |              13,070     |
 | 10/31/92     |            13,259     |              13,118     |
 | 11/30/92     |            13,709     |              13,555     |
 | 12/31/92     |            13,878     |              13,713     |
 |  1/31/93     |            13,995     |              13,811     |
 |  2/28/93     |            14,185     |              13,982     |
 |  3/31/93     |            14,484     |              14,277     |
 |  4/30/93     |            14,134     |              13,917     |










 |  5/31/93     |            14,511     |              14,286     |
 |  6/30/93     |            14,553     |              14,322     |
 |  7/31/93     |            14,495     |              14,259     |
 |  8/31/93     |            15,044     |              14,794     |
 |  9/30/93     |            14,928     |              14,669     |
 | 10/31/93     |            15,237     |              14,973     |
 | 11/30/93     |            15,093     |              14,819     |
 | 12/31/93     |            15,271     |              14,993     |
 |                                                                |
 |

 | ----------------------------------------------------------------------------|
 |                 DREYFUS LIFE AND ANNUITY INDEX FUND                         |
 | ----------------------------------------------------------------------------|
 |          AVERAGE ANNUAL TOTAL RETURNS ENDED ON 12/31/93                     |
 | ----------------------------------------------------------------------------|
 |                                      |     SINCE INCEPTION                  |
 |                       1 YEAR         |        (9/29/89)                     |
 | ----------------------------------------------------------------------------|
 |                             9.33%    |                9.98%                 |
 | ----------------------------------------------------------------------------|




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