May 12, 1998
Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, N.W.
Washington, D.C. 20549
Attention: Filings - Rule 497(j)
Re: Dreyfus Life and Annuity Index Fund, Inc.
d/b/a Dreyfus Stock Index Fund
CIK No. 0000846800
1940 Act File No. 811-05719
Registration Statement File No. 33-27172
Dear Sir/Madam:
Pursuant to Rule 497(j) under the Securities Act of
1933, please be advised that there are no changes to the
Prospectus and Statement of Additional Information contained
in Post-Effective Amendment No. 10 to the Fund's
Registration Statement on Form N-1A filed pursuant to Rule
485(b) with the Securities and Exchange Commission on April
29, 1998.
Please address any comments or questions to the
undersigned at (212) 922-6806.
Very truly yours,
Judy Nieves
Paralegal