DREYFUS LIFE & ANNUITY INDEX FUND INC, 497J, 1999-05-10

DREYFUS LIFE & ANNUITY INDEX FUND INC
497J, 1999-05-10

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                                                           May 10, 1999



Securities and Exchange Commission
Judiciary Plaza
450 Fifth Street, N.W.
Washington, D.C.  20549

        Re:     Dreyfus Stock Index Fund (the "Fund")
                Registration Statement File Nos. 33-27172; 811-5719

Ladies and Gentlemen:

        This filing is being made pursuant to Rule 497(j) under the Securities
Act of 1933, as amended (the "1933 Act"), for the purpose of informing the SEC
that there were no material or non-material changes since the Registrant's Post-
Effective Am endment No. 12 filed with the SEC on April 27, 1999.

        If you have any questions or comments on the attached, please do not
hesitate to contact the undersigned at (212) 922-6855.


                                                           Very truly yours,



                                                            Lisa R. Grosswirth




cc:     Stroock & Stroock & Lavan
        Ernst & Young
        Michael A. Rosenberg