U S BIOSCIENCE INC
424B3, 1996-06-26
PHARMACEUTICAL PREPARATIONS
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                                    Registration Statement No. 33-77376
                                    Filed pursuant to Rule 424(b)(3)
                                    under the Securities Act of 1933
       
       
       
       Rider to Prospectus dated September 8, 1994
       Relating to Shares Underlying Warrants
       
       
                         U.S. BIOSCIENCE, INC.
                             Common Stock
       
       Effective the close of business April 22, 1996, U.S. Bioscience,
       Inc. effected a 1-for-2 reverse stock split of its Common Stock,
       reducing by 50% the number of outstanding shares of Common Stock. 
       In connection with the reverse stock split, the par value of the
       Common Stock was changed from $.005 per share to $.01 per share.
       Effective the opening of business April 23, 1996 it will require
       two warrants, rather than one warrant, to purchase one share of
       Common Stock, par value $.01 per share, and the exercise price
       for the two warrants will be $18.40 to purchase one share rather
       than $9.20 to purchase one share.  For example, if on April 22,
       1996 you held a warrant certificate representing 100 warrants to
       purchase 100 shares at a price of $9.20 per share (aggregate
       exercise price $920), that certificate now represents 100
       warrants to purchase 50 shares at an exercise price of $18.40 per
       share (aggregate exercise price $920).


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