NEUROGEN CORP
10-Q, 1995-08-10
PHARMACEUTICAL PREPARATIONS
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<PAGE>
 
                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549
                                        
                                   FORM 10-Q

           [x]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934
                  For the quarterly period ended June 30, 1995
                                       OR
           [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                         Commission File Number 0-18311


                              NEUROGEN CORPORATION
             (Exact name of registrant as specified in its charter)

                    Delaware                        22-2845714
          (State or other jurisdiction of        (I.R.S. Employer
         incorporation or organization)         Identification No.)

          35 Northeast Industrial Road
             Branford, Connecticut                    06405
      (Address of principal executive offices)      (Zip Code)

                                 (203) 488-8201
              (Registrant's telephone number, including area code)

  Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

                    Yes  X            No
                        ---             ---


  As of August 9, 1995, the registrant had 10,138,333 shares of Common Stock
outstanding.
<PAGE>
 
                              NEUROGEN CORPORATION

                                     INDEX

<TABLE>  
<CAPTION> 

                                                                           Page
                                                                          Number
                                                                          ------

                         Part I - Financial Information


 
 
<S>        <C>                                                              <C>
Item 1.    Financial Statements...........................................     1
 
           Balance Sheets at June 30, 1995 and
           December 31, 1994..............................................   1,2
           Statements of Operations and Accumulated Deficit for the
           three-month periods ended June 30, 1995 and 1994 and for the
           six-month periods ended June 30, 1995 and 1994.................     3
           Statements of Cash Flows for the six-month periods ended
           June 30, 1995 and 1994.........................................     4
           Notes to Financial Statements..................................   5-6
 
Item 2.    Management's Discussion and Analysis of Financial Condition and
           Results of Operations..........................................  7-11
</TABLE>

<TABLE>  
<CAPTION> 
                          Part II - Other Information

<S>          <C>                                                  <C>
Item 1.      Legal Proceedings..................................  11
 
Item 2.      Changes in Securities..............................  11
 
Item 3.      Defaults upon Senior Securities....................  11
 
Item 4.      Submission of Matters to a Vote of Security Holders  11
 
Item 5.      Other Information..................................  12
 
Item 6.      Exhibits and Reports on Form 8-K...................  12
 
Signature    ...................................................  13
</TABLE>

                                       i
<PAGE>
 
                        PART I - FINANCIAL INFORMATION

ITEM 1 - FINANCIAL STATEMENTS


                             NEUROGEN CORPORATION
                                BALANCE SHEETS

<TABLE> 
<CAPTION> 
                                                  JUNE 30,        DECEMBER 31,
                                                    1995             1994
                                                 (UNAUDITED)       (AUDITED)
                                                 -----------       ---------
                          Assets             
<S>                                              <C>               <C> 
Current assets:                              
  Cash and cash equivalents                      $ 24,246,293      $  9,439,727
  Marketable securities                             5,697,547         6,040,434
  Other current assets                                333,465           398,542
                                                 ------------      ------------
    Total current assets                           30,277,305        15,878,703

Property, plant & equipment:
  Land                                                425,000           425,000
  Building                                          8,401,582         8,379,703
  Equipment                                         2,938,801         2,297,728
  Furniture                                           140,364           110,668
  Equipment and furniture under capital lease               -         1,200,000
                                                 ------------      ------------
                                                   11,905,747        12,413,099
  Less accumulated depreciation                     1,750,161         2,588,476
                                                 ------------      ------------ 
   Net property, plant and equipment               10,155,586         9,824,623
Other assets, net                                     206,446           185,752
                                                 ------------      ------------ 
                                                 $ 40,639,337      $ 25,889,078
                                                 ============      ============
</TABLE> 

See accompanying notes to financial statements.

                                       1
<PAGE>
 
                             NEUROGEN CORPORATION
                                BALANCE SHEETS

<TABLE>
<CAPTION>
                                                    June 30,     December 31,
                                                      1995           1994
                                                  (Unaudited)     (Audited)
                                                 -------------  -------------
<S>                                              <C>            <C>
        Liabilities and Stockholders' Equity
Current Liabilities:
  Accrued expenses                                $  1,021,766  $    949,717
  Unearned revenue from collaborative partner        3,900,000             -
  Current portion of mortgage payable                  150,178       141,125
  Current portion of capital lease obligation                -        30,863
                                                  ------------  ------------
    Total current liabilities                        5,071,944     1,121,705

Mortgage payable, excluding current portion            542,464       619,887
Other compensation                                      62,587        62,587
Deferred gain on sale of assets                              -         4,375
                                                  ------------  ------------

    Total liabilities                                5,676,995     1,808,554

Stockholders' Equity:
  Preferred stock, par value $.025 per share.
    Authorized 2,000,000 shares; none issued
  Common stock, par value $.025 per share.
    Authorized 30,000,000 shares; issued and
     outstanding 10,128,133 shares at June 30,
     1995 and 10,082,763 shares at
     December 31, 1994                                 253,203       252,069
  Additional paid-in capital                        45,806,431    45,607,590
  Accumulated deficit                              (11,232,368)  (21,766,182)
  Unrealized gain (loss) on marketable securities      135,076       (12,953)
                                                  ------------  ------------
    Total stockholders' equity                      34,962,342    24,080,524
                                                  ------------  ------------
                                                  $ 40,639,337  $ 25,889,078
                                                  ============  ============
</TABLE>


See accompanying notes to financial statements.

                                       2
<PAGE>

<TABLE> 
<CAPTION>                                                        
                                                       NEUROGEN CORPORATION
                                         STATEMENTS OF OPERATIONS AND ACCUMULATED DEFICIT

                                     Three Months    Three Months      Six Months      Six Months   
                                        Ended           Ended            Ended           Ended       
                                     June 30, 1995   June 30, 1994    June 30, 1995   June 30, 1994  
                                      (Unaudited)     (Unaudited)      (Unaudited)     (Unaudited)   
                                      -----------     -----------      -----------     -----------    
<S>                                  <C>             <C>              <C>             <C> 
Operating revenues:                
  License fees                       $ 14,000,000    $          -     $ 14,000,000    $          -  
  Research revenue                      1,869,666       1,150,000        3,739,333       2,300,000
                                     ------------    ------------     ------------    ------------  
    Total operating revenues           15,869,666       1,150,000       17,739,333       2,300,000 
                         
Operating expenses:      
  Research & development                2,845,719       1,983,893        5,889,691       4,343,649
  General & administrative                817,870         828,624        1,506,302       1,626,151
                                     ------------    ------------     ------------    ------------   
    Total operating expenses            3,663,589       2,812,517        7,395,993       5,969,800

Other income (expense):
  Investment income                       273,095          96,928          453,470         152,589
  Interest expense                        (17,897)        (22,846)         (35,996)        (48,057)
                                     ------------    ------------     ------------    ------------  
    Total other income, net               255,198          74,082          417,474         104,532

Net income (loss) before provision  
 for income taxes                    $ 12,461,275    $ (1,588,435)    $ 10,760,814    $ (3,565,268)
Provision for income taxes           $    227,000               -     $    227,000               -
                                     ------------    ------------     ------------    ------------ 
Net income (loss)                    $ 12,234,275    $ (1,588,435)    $ 10,533,814    $ (3,565,268)  
                                     ------------    ------------     ------------    ------------   
Earnings (loss) per share:                                                                            
  Primary                            $       1.10    $      (0.18)    $       0.96    $      (0.40)    
                                     ============    ============     ============    ============     
  Fully diluted
                                     $       1.07    $          -     $       0.93    $          -    
                                     ============    ============     ============    ============    
Shares used in calculation of
 earnings (loss) per share:                                            
  Primary                              11,172,000       8,974,000       10,958,000       8,972,000   
                                     ============    ============     ============    ============   
  Fully diluted
                                       11,401,000               -       11,381,000               -   
                                     ============    ============     ============    ============    
Accumulated deficit:
  Beginning of period                $(23,466,643)   $(17,091,820)    $(21,766,182)   $(15,114,987) 
                                     ------------    ------------     ------------    ------------   
  End of period                      $(11,232,368)   $(18,680,255)    $(11,232,368)   $(18,680,255)   
                                     ============    ============     ============    ============     
</TABLE> 

See accompanying notes to condensed financial statements.

                                                3
<PAGE>
 
                             NEUROGEN CORPORATION
                           STATEMENTS OF CASH FLOWS

<TABLE>
<CAPTION>
                                                   Six Months     Six Months
                                                 Ended June 30, Ended June 30, 
                                                      1995           1994
                                                  (Unaudited)     (Unaudited)
                                                 -------------- --------------
<S>                                              <C>             <C>
Cash flows from operating activities:
  Net income (loss)                               $ 10,533,814   $ (3,565,268)
  Adjustments to reconcile net income (loss)
   to net cash provided by (used in) operating  
   activities:
    Depreciation and amortization expense              376,173        427,131
    Unrealized loss on marketable securities                 -         61,474
    Net loss (gain) on sale of assets                    3,053        (13,125)
  Changes in operating assets and liabilities:
    Increase in accrued expenses                        72,043         29,184
    Increase in unearned revenue from 
     collaborative partner                           3,900,000              -
    Decrease in other current assets                    65,076         74,866
    Increase in other assets, net                      (29,610)      (149,275)
                                                  -------------  -------------
      Net cash provided by (used in) operating
       activities                                   14,920,549     (3,135,013)
                                                  -------------  -------------

Cash flows from investing activities:
  Purchase of plant and equipment                     (705,648)      (277,679)
  Purchases of marketable securities                (7,573,237)    (8,360,449)
  Sales of marketable securities                     8,064,154      8,224,197
                                                  -------------  -------------
    Net cash used in investing activities             (214,731)      (413,931)
                                                  -------------  -------------

Cash flows from financing activities:
  Exercise of employee stock options                   199,976              -
  Exercise of warrants                                       -         50,000
  Principal payments under mortgage payable            (68,370)       (60,375)
  Principal payments under capital lease 
   obligations                                         (30,858)      (169,510) 
                                                  -------------  -------------
    Net cash provided by (used in) financing 
     activities                                        100,748       (179,885)
                                                  -------------  -------------

    Net increase (decrease) in cash and cash
     equivalents                                    14,806,566     (3,728,829)

Cash and cash equivalents at beginning of period     9,439,727      6,403,987
                                                  -------------  -------------

Cash and cash equivalents at end of period        $ 24,246,293   $  2,675,158
                                                  =============  =============
</TABLE>


See accompanying notes to financial statements.

                                       4

<PAGE>
 
                             NEUROGEN CORPORATION
                         NOTES TO FINANCIAL STATEMENTS
                                 JUNE 30, 1995
                                  (UNAUDITED)



(1)  Basis of Presentation and Summary of Significant Accounting Policies
     ---------------------------------------------------------------------

          The unaudited financial statements have been prepared from the books
     and records of Neurogen Corporation (the "Company") in accordance with
     generally accepted accounting principles for interim financial information
     pursuant to Rule 10-01 of Regulation S-X. Accordingly, they do not include
     all of the information and footnotes required by generally accepted
     accounting principles for complete financial statements. In the opinion of
     management, all adjustments (consisting of normal recurring accruals)
     considered necessary for a fair presentation have been included. Interim
     results are not necessarily indicative of the results that may be expected
     for the fiscal year.

(2)  Agreement with Schering-Plough Corporation
     ------------------------------------------

          In June 1995, Neurogen and Schering Corporation and Schering-Plough
     Ltd. (together, "Schering-Plough") Schering-Plough entered into the
     Collaboration and License Agreement dated as of June 28, 1995 (the
     "Schering-Plough Agreement") to collaborate in the discovery and
     development of antipsychotics and drugs for other disorders which act
     through the dopamine family of receptors. Pursuant to the Schering-Plough
     Agreement, the Company received one-time license fees of $14.0 million for
     the rights to Neurogen's dopamine compounds and $3.0 million for the right
     to test Neurogen's combinatorial chemistry libraries in selected non-CNS
     assays. Schering-Plough also agreed to pay an additional $3.0 million in
     1996 for the right to test additional libraries. Moreover, Neurogen is
     entitled to receive approximately $7.2 million during the two-year period
     which commenced June 28, 1995 for research and development funding of the
     Company's antipsychotic program and may receive additional research and
     development funding of up to $3.6 million per year for three additional 
     one-year periods depending on whether and the extent to which Schering-
     Plough exercises its right to extend the collaboration beyond July 1997.
     Neurogen could also receive milestone payments of up to approximately $32.0
     million if it achieves certain development and regulatory objectives
     regarding its products subject to the collaboration. In return, Schering-
     Plough received the exclusive worldwide license to market products subject
     to the collaboration and Neurogen retained the rights to receive royalties
     based on net sales levels, if any. In addition to the payments described
     above, Schering-Plough is responsible for funding the cost of all clinical
     development and marketing, if any, of drugs subject to the collaboration.

                                       5
<PAGE>
 
(3)  Earnings per Common Share
     -------------------------

          Earnings per common share are computed in accordance with the treasury
     stock method.  Primary and fully diluted earnings per share are based upon
     the weighted average number of common shares and dilutive common stock
     equivalents outstanding.  Common stock equivalents include outstanding
     options under the Company's stock option plan and outstanding warrants to
     purchase shares of the Company's common stock. The common stock equivalents
     have not been included in periods with losses as their inclusion would be 
     antidilutive.

(4)  Filing of Registration Statement
     --------------------------------

          In July 1995, the Company filed a Registration Statement with the
     Securities and Exchange Commission to offer and sell up to 2,875,000 shares
     of common stock through an underwritten public offering. The offering is
     expected to be completed in the third quarter of 1995.

                                       6
<PAGE>
 
     ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF
              FINANCIAL CONDITION AND RESULTS OF OPERATIONS

          Since its inception in September 1987, Neurogen has been engaged in
     the discovery and development of proprietary therapeutic products for the
     treatment of psychiatric and neurological disorders. The Company has not
     derived any revenue from product sales and excluding the effect of
     $14,000,000 in one-time license fees received from Schering-Plough in 1995,
     expects to incur significant and increasing losses over at least the next
     several years, as it continues to expand its discovery and development
     programs. Its revenues to date have come from two collaborative research
     agreements entered into with Pfizer Inc. ("Pfizer"), one collaboration and
     license agreement with Schering-Plough and from interest income. The
     Company and Pfizer entered into the Collaborative Research Agreement dated
     as of January 1, 1992 (the "1992 Pfizer Agreement") to collaborate with
     respect to the development of compounds for anxiety and cognition
     disorders. The Company and Pfizer entered into the Collaborative Research
     Agreement dated as of July 1, 1994 (the "1994 Pfizer Agreement" and
     together with the 1992 Pfizer Agreement, the "Pfizer Agreements") to
     collaborate with respect to its sleep disorder program. The Company entered
     into the Schering-Plough Agreement in June 1995 to develop and market
     compounds for the treatment of psychiatric disorders which act through the
     dopamine family of receptors.

     RESULTS OF OPERATIONS

          Results of operations may vary from period to period depending on
     numerous factors, including the timing of payments received under existing
     or future strategic alliances, joint ventures or financings, if any, the
     progress of the Company's research and development projects, technological
     advances and determinations as to the commercial potential of proposed
     products. Neurogen expects research and development costs to increase
     significantly over the next several years as its drug development programs
     progress. In addition, general and administrative expenses necessary to
     support the expanded research and development activities are expected to
     increase for the foreseeable future.

     THREE MONTHS ENDED JUNE 30, 1995 AND 1994

          In June 1995, the Company received, and recognized as revenue,
     $14,000,000 in one-time license fees from Schering-Plough in connection
     with entering into the Schering-Plough Agreement. The Company's operating
     revenues were $15,869,666 for the three months ended June 30, 1995 compared
     to $1,150,000 for the same period in 1994. This increase is due primarily
     to the above-referenced $14,000,000 in one-time license fees. Research 
     funding pursuant to the Pfizer Agreements increased 63% for the three-month
     period ended June 30, 1995 compared to the same period in 1994, due to the
     commencement of the 1994 Pfizer Agreement in the third quarter of 1994. The
     Company will begin recognizing research revenue under the Schering-Plough
     Agreement in the third quarter of 1995. Research funding under the 1992
     Pfizer Agreement, which has represented $4.6 million per year for the last
     three years, is scheduled to terminate at the end of 1995 if Pfizer does
     not extend the collaboration.

          Research and development costs have increased $861,826, or 43%, to
     $2,845,719 for the three-month period ended June 30, 1995 as compared to
     the same period in 1994. This increase is due primarily to expansion of
     preclinical and clinical testing on the Company's lead antipsychotic
     compound, increased staffing levels and purchases of laboratory equipment,
     materials and supplies. Research and development costs represented 78% of
     total operating expenses for the second quarter of 1995 as compared to 71%
     for the same period in 1994.

                                       7
<PAGE>
 
          General and administrative expenses decreased $10,754, or 1%, to
     $817,870 for the three-month period ended June 30, 1995 as compared to the
     same period in 1994.

          Other revenues, consisting primarily of interest income and gains and
     losses from U.S. government securities, increased 182% for the second
     quarter of 1995 compared to the same period in 1994 due to realized gains
     on U.S. government securities and a higher level of invested funds.

          The Company recognized net income of $12,234,275 for the three months
     ended June 30, 1995 as compared with a net loss of $1,588,435 for the same
     period in 1994.  The net income in 1995 is primarily due to the increase in
     revenues resulting from one-time license fees of $14,000,000 from Schering-
     Plough Corporation for the rights to Neurogen's dopamine compounds.

     SIX MONTHS ENDED JUNE 30, 1995 AND 1994

          In June 1995, the Company received, and recognized as revenue,
     $14,000,000 in one-time license fees from Schering-Plough in connection
     with entering into the Schering-Plough Agreement. The Company's operating
     revenues were $17,739,333 for the six months ended June 30, 1995 compared
     to $2,300,000 for the same period in 1994. This increase is due primarily
     to the above-referenced $14,000,000 in one-time license fees. In addition,
     research funding pursuant to the Pfizer Agreements increased 63% for the
     six-month period ended June 30, 1995 compared to the same period in 1994,
     due to the commencement of the 1994 Pfizer Agreement in the third quarter
     of 1994. The Company will begin recognizing research revenue under the
     Schering-Plough Agreement in the third quarter of 1995. Research funding
     under the 1992 Pfizer Agreement, which has represented $4.6 million per
     year for the last three years, is scheduled to terminate at the end of 1995
     if Pfizer does not extend the collaboration.

          Research and development costs have increased $1,546,042 or 36% to
     $5,889,691 for the six-month period ended June 30, 1995 as compared to the
     same period in 1994.  This increase is due primarily to expansion of
     preclinical and clinical testing on the Company's lead  antipsychotic
     compound, increased staffing levels and purchases of laboratory equipment,
     materials and supplies.  Research and development costs represented 80% of
     total operating expenses for the first six months of 1995 as compared to
     73% for the same period in 1994.  

          General and administrative expenses decreased $119,849 or 7% for the
     six-month period ended June 30, 1995 as compared to the same period in
     1994.  This decrease is primarily attributable to a refinement in the
     Company's allocation of expenses between research and development and
     general and administrative and to a general reduction of expenses in
     several areas.  

          Other revenues, consisting primarily of interest income and gains and
     losses from U.S. government securities, increased 197% for the first six
     months of 1995 compared to the same period in 1994 due to higher interest
     rates, realized gains on U.S. government securities and a higher level of
     invested funds.

       The Company recognized net income of $10,533,814 for the six-month period
     ended June 30, 1995 as compared with a net loss of $3,565,268 for the same
     period in 1994.  The net income in 1995 is primarily due to the increase in
     revenues resulting from one-time license fees of $14,000,000.

                                       8
<PAGE>
 
     from Schering-Plough Corporation for the rights to Neurogen's dopamine
     compounds.

       In 1993 and 1994, respectively, the Company adopted Financial Accounting
     Standards Board Statements No. 109, "Accounting for Income Taxes" ("SFAS
     109") and, No. 115, "Accounting for Certain Investments in Debt and Equity
     Securities" ("SFAS 115").  Adoption of SFAS 109 and 115 did not have a
     significant impact on the Company's financial statements.

     LIQUIDITY AND CAPITAL RESOURCES
 
          At June 30, 1995 and December 31, 1994, cash, cash equivalents and
     marketable securities were in the aggregate $29,944,000 and $15,480,000,
     respectively. The increase in 1995 was primarily due to $17,900,000
     (including $3,900,000 of unearned revenue) received from Schering-Plough in
     connection with entering into the Schering-Plough Agreement, offset in part
     by the application of such resources to fund operations. At December 31,
     1994, 1993 and 1992, cash, cash equivalents and marketable securities were
     in the aggregate $15,480,000, $12,326,000 and $19,423,000, respectively.
     The increase in 1994 was due to cash received pursuant to the 1994 Pfizer
     Agreement. The decrease in 1993 was primarily a result of $3,382,699 in
     cash required to fund operations in excess of cash generated from
     operations, together with office and research facility and equipment
     additions of $3,075,347. The Company's aggregate level of cash, cash
     equivalents and marketable securities have fluctuated in the past and are
     expected to fluctuate in the future as a result of the factors described
     below.

          Neurogen's cash requirements to date have been met by the proceeds of
     its financing activities, including interest earned on such proceeds and
     research funding received pursuant to the Pfizer Agreements and the
     Schering-Plough Agreement and one-time license fees from the Schering-
     Plough Agreement. The Company's financing activities have included three
     private placement offerings of the Company's common stock during 1988 and
     1989, a public offering of the Company's common stock in each of 1989 and
     1991 and the sale of common stock to Pfizer in 1992 and 1994 in connection
     with entering into the Pfizer Agreements. Total funding received from these
     financing activities was approximately $45,400,000. The Company's
     expenditures have been primarily to fund research and development and
     general and administrative expenses including hiring, management and
     administrative personnel, and to construct and equip its research and
     development facility.

          In the first quarter of 1992, the Company entered into the 1992 Pfizer
     Agreement effective January 1992 pursuant to which Pfizer made a
     $13,750,000 equity investment in the Company. Pursuant to the 1992 Pfizer
     Agreement, the Company expects to receive approximately $18,400,000 during
     the four-year period which commenced January 1, 1992 for research and
     development funding of the Company's anxiolytic (anxiety-reducing drugs)
     and cognitive enhancer programs, and may receive up to an additional
     $4,600,000 for a fifth year should Pfizer exercise its option to extend the
     collaboration. Neurogen could also receive milestone payments of up to
     $12,500,000 during the development and regulatory approval of its products.
     In return, Pfizer received the exclusive rights to manufacture and market
     anxiolytics that act through the family of receptors which interact with
     the neuro-transmitter gama-aminobutyric acid, or GABA, and cognition
     enhancers developed in the collaboration for which it will pay Neurogen
     royalties based upon net sales levels, if any, for such products. As of
     June 30, 1995, Pfizer had provided $16,100,000 of research funding to the
     Company pursuant to the 1992 Pfizer Agreement, in addition to its equity
     investment in 1992.

          Neurogen and Pfizer entered into their second collaborative agreement,
     the 1994 Pfizer Agreement, in July 1994, pursuant to which Pfizer
     provided $9,864,000 in equity financing. Pursuant to the 1994 Pfizer
     Agreement, the
                                       9
<PAGE>
 
     Company expects to receive approximately $7,386,000 during the three-year
     period which commenced July 1, 1994, for research and development funding
     of the Company's sleep disorder program and may receive up to an additional
     $2,379,000 for a fourth year should Pfizer exercise its option to extend
     the collaboration. Neurogen could also receive milestone payments of up to
     $3,250,000 during the development and regulatory approval of its sleep
     disorder compounds. As part of this second collaboration, Pfizer received
     the exclusive rights to manufacture and market GABA-based sleep disorder
     products developed in the collaboration for which it will pay Neurogen
     royalties depending upon net sales levels, if any. As of June 30, 1995,
     Pfizer had provided $2,628,667 of research funding to the Company pursuant
     to the 1994 Pfizer Agreement, in addition to its equity investment in 1994.

          Under both the 1992 Pfizer Agreement and the 1994 Pfizer Agreement, in
     addition to making the equity investments and  the research and milestone
     payments noted above, Pfizer is responsible for funding the cost of all
     clinical development and marketing, if any, of drugs developed from the
     collaboration.

          In June 1995, Neurogen and Schering-Plough entered into the Schering-
     Plough Agreement pursuant to which Neurogen and Schering-Plough are
     collaborating in the discovery and development of antipsychotics and drugs
     for other disorders which act through the dopamine family of receptors.
     Pursuant to the Schering-Plough Agreement, the Company received one-time
     license fees of $14,000,000 for the rights to Neurogen's dopamine compounds
     and $3,000,000 for the right to test certain of Neurogen's combinatorial
     chemistry libraries in selected non-CNS assays. Schering-Plough also agreed
     to pay an additional $3,000,000 in 1996 for the right to test additional
     libraries. Moreover, Neurogen expects to receive approximately $7,200,000
     during the two-year period which commenced June 28, 1995, of which $900,000
     had been paid as of June 30, 1995, for research and development funding of
     the Company's antipsychotic program. The Company may receive additional
     research and development funding of up to $3,600,000 per year for three
     additional one-year periods depending on whether and the extent to which
     Schering-Plough exercises its right to extend the collaboration. Neurogen
     could also receive milestone payments of up to approximately $32,000,000 if
     it achieves certain development and regulatory objectives regarding its
     products subject to the collaboration. In return, Schering-Plough received
     the exclusive worldwide license to market products subject to the
     collaboration and Neurogen retained the rights to receive royalties based
     on net sales levels, if any.

          The Company plans to use its cash balance for its research and
     development activities, working capital and general corporate purposes.
     Neurogen anticipates that its cash balance, as supplemented by research
     funding pursuant to the Pfizer Agreements and the Schering-Plough
     Agreement, will be sufficient to fund its current and planned operations
     through 1997.  However, Neurogen's funding requirements may change and will
     depend upon numerous factors, including but not limited to, the progress of
     the Company's research and development programs, the timing and results of
     preclinical testing and clinical studies, the timing of regulatory
     approvals, technological advances, determinations as to the commercial
     potential of its proposed products, the status of competitive products and
     the ability of the Company to establish and maintain collaborative
     arrangements with others for the purpose of funding certain research and
     development programs, conducting clinical studies, obtaining regulatory
     approvals and, if such approvals are obtained, manufacturing and marketing
     products.  The Company anticipates that it will augment its 

                                       10
<PAGE>
 
     cash balance through financing transactions, including the issuance of debt
     or equity securities and further corporate alliances. No arrangements have
     been entered into for any future financing and no assurances can be given
     that adequate levels of additional funding can be obtained on favorable
     terms, if at all.

     As of December 31, 1994, for federal income tax purposes, the Company had
     generated net operating loss carryforwards of approximately $22,800,000,
     which are scheduled to expire in the years 2003 through 2009. A
     significant portion of these net operating loss carryforwards will be
     utilized in 1995 as a result, in part, of one-time payments received and
     corresponding revenues recognized pursuant to the Schering-Plough
     Agreement. Future issuance of securities by the Company and/or sales of
     securities by the Company's principal shareholders could result in an
     ownership change as defined by Section 382 of the Internal Revenue Code of
     1986. Such an ownership change could limit the Company's utilization of
     net operating loss carryforwards to offset future taxable income, if any.

                                       11
<PAGE>
 
                          PART II - OTHER INFORMATION



ITEM 1.  LEGAL PROCEEDINGS

         Not applicable for the quarter ended June 30, 1995.


ITEM 2.  CHANGES IN SECURITIES
  
         Not applicable for the quarter ended June 30, 1995.


ITEM 3.  DEFAULTS UPON SENIOR SECURITIES

         Not applicable for the quarter ended June 30, 1995.


ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         On June 6, 1995 the Company held its annual meeting of stockholders (i)
to elect a board of eleven directors (Proposal 1) and (ii) to approve the
appointment by the Board of Directors of KPMG Peat Marwick LLP as the
independent auditors for the Company for fiscal year ending December 31, 1995 
(Proposal 2).

         The stockholders elected the persons named below, the Company's
nominees for directors, as directors of the Company, casting votes in favor of
such nominees or withholding votes as indicated:

 
                                         Votes in Favor  Votes Withheld
                                         --------------  ---------------
                                         
Barry M. Bloom, Ph.D.                    6,147,791              500
Robert N. Butler, M.D.                   6,147,791              500
Frank C. Carlucci                        6,147,791              500
Jeffrey J. Collinson                     6,147,791              500
Robert M. Gardiner                       6,147,791              500
Richard D. Harrison                      6,147,791              500
Mark Novitch, M.D.                       6,147,791              500
Harry H. Penner, Jr.                     6,147,791              500
Robert H. Roth, Ph.D.                    6,147,791              500
John Simon                               6,147,791              500
John F. Tallman, Ph.D.                   6,147,791              500
 
      The Stockholders approved Proposal 2, voting as follows:
 
                    Affirmative Votes      Negative Votes  Votes Abstained
                    -----------------      --------------  ---------------
                                           
                       6,147,791                0              500

                                       12
<PAGE>
 
        Of the shares held by brokers, shares not voted were as follows:
                                        
                                            Not Voted
                                            ---------
Proposal 1                                     -0-
Proposal 2                                     -0-

ITEM 5.  OTHER INFORMATION

         Not applicable for the quarter ended June 30, 1995.


ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

     (b) Reports on Form 8-K
         -------------------
 
         The Company filed a Current Report on Form 8-K, dated June 15, 1995,
         reporting in Item 5 that the Company had entered into the Schering-
         Plough Agreement to jointly develop a new generation of pharmaceuticals
         that bind selectively to specific dopamine receptor sub-types. The Form
         8-K included in Item 7 a copy of the news release dated June 15, 1995,
         announcing the matters described in Item 5 of the Form 8-K. The Company
         filed a Current Report on Form 8-K, dated July 28, 1995, including in
         Item 7 a copy of the Schering-Plough Agreement with certain
         confidential matters omitted under a request for Confidential
         Treatment.

         The Company made no other filings on Form 8-K during the quarter ended
         June 30, 1995.

                                       13
<PAGE> 
 
                                   Signature



     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                      NEUROGEN CORPORATION



                                      By:/s/ STEPHEN R. DAVIS
                                        -----------------------
                                         Stephen R. Davis
                                         Vice President-Finance and
                                         Chief Financial Officer


Date:  August 10, 1995
<PAGE>
 
                                 Exhibit Index
                                 -------------

      Exhibit
      -------
      Number
      ------

      10.1  - Neurogen Corporation Stock Option Plan, as amended (incorporated
              by reference to Exhibit 10.1 to the Company's Form 10-K for the
              fiscal year ended December 31, 1991).

      10.2  - Form of Stock Option Agreement currently used in connection with
              the grant of options under Neurogen Corporation Stock Option Plan
              (incorporated by reference to Exhibit 10.2 to the Company's Form
              10-K for the fiscal year ended December 31, 1992).

      10.3  - Neurogen Corporation 1993 Omnibus Incentive Plan, as amended
              (incorporated by reference to Exhibit 10.3 to the Company's Form
              10-K for the fiscal year ended December 31, 1993).

      10.4  - Form of Stock Option Agreement currently used in connection with
              the grant of options under Neurogen Corporation 1993 Omnibus
              Incentive Plan (incorporated by reference of Exhibit 10.4 to the
              Company's Form 10-K for the fiscal year ended December 31, 1993).

      10.5  - Neurogen Corporation 1993 Non-Employee Directors Stock Option
              Program (incorporated by reference to Exhibit 10.5 to the
              Company's Form 10-K for the fiscal year ended December 31, 1993).

      10.6  - Form of Stock Option Agreement currently used in connection with
              the grant of options under Neurogen Corporation 1993 Non-Employee
              Directors Stock Option Program (incorporated by reference to
              Exhibit 10.6 to the Company's Form 10-K for the fiscal year ended
              December 31, 1993).

      10.7  - Employment Contract between the Company and Harry H. Penner, Jr.,
              dated as of October 12, 1993 (incorporated by reference to Exhibit
              10.7 to the Company's Form 10-K for the fiscal year ended December
              31, 1993).

      10.8  - Employment Contract between the Company and John F. Tallman,
              dated as of December 1, 1993 (incorporated by reference to Exhibit
              10.25 to the Company's Form 10-Q for the quarterly period ended
              September 30, 1994).

      10.9  - Open-End Mortgage Deed and Security Agreement between the Company
              and Orion Machinery & Engineering Corp., dated March 16, 1989
              (incorporated by reference to Exhibit 10.15 to Registration
              Statement  No. 33-29709 on Form S-1).

                                      15
<PAGE>
 
     10.10  - Construction Agreement between the Company and Frank E. Downes
              Construction Company, Inc., dated August 25, 1992 (incorporated
              by reference to Exhibit 10.17 to the Company's Form 10-K for the
              fiscal year ended December 31, 1992).
    
     10.11  - Letter Agreement between the Company and Biotechnology Venture
              Fund S.A., dated August 5, 1988 (incorporated by reference to
              Exhibit 10.26 to Registration Statement No. 33-29709 on Form S-1).
    
     10.12  - Letter Agreement between the Company and Biotechnology Venture
              Fund S.A., dated February 5, 1989 (incorporated by reference to
              Exhibit 10.27 to Registration Statement No. 33-29709 on Form S-1).
    
     10.13  - Letter Agreement between David Blech and Peter McPartland, dated
              February 17, 1989 (incorporated by reference to Exhibit 10.28 to
              Registration Statement No. 33-29709 on Form S-1).
    
     10.14  - Letter Agreement between David Blech and Isaac Blech and Michael
              Drew, dated February 21, 1989 (incorporated by reference to
              Exhibit 10.29 to Registration Statement No. 33-29709 on Form S-1).
    
     10.15  - Letter Agreement between the Company and Schroder International
              Trust Co., Ltd., dated February 24, 1989 (incorporated by
              reference to Exhibit 10.30 to Registration Statement No. 33-29709
              on Form S-1).
    
     10.16  - Form of Proprietary Information and Inventions Agreement
              (incorporated by reference to Exhibit 10.31 to Registration
              Statement No. 33-29709 on Form S-1).
    
     10.17  - Warrant to Purchase 47,058 Shares of Common Stock to MMC/GATX
              Partnership No. I, dated February 20, 1991 (incorporated by
              reference to Exhibit 10.34 to the Company's Form 10-K for the
              fiscal year ended December 31, 1990).
    
     10.18  - Collaborative Research Agreement between the Company and Pfizer
              Inc, dated as of January 1, 1992 (incorporated by reference to
              Exhibit 10.35 to the Company's Form 10-K for the fiscal year ended
              December 31, 1991).
    
     10.19  - License Agreement between the Company and the National Technical
              Information Service, dated as of January 1, 1992 (incorporated by
              reference to Exhibit 10.36 to the Company's Form 10-K for the
              fiscal year ended December 31, 1991).

                                      16
<PAGE>
 
     10.20 -  Cooperative Research and Development Agreement between the Company
              and the National Institutes of Health, dated as of January 21,
              1992 (incorporated by reference to Exhibit 10.37 to the Company's
              Form 10-K for the fiscal year ended December 31, 1991).

     10.21  - Letter Agreement between the Company and Robert H. Roth dated
              April 14, 1994 (incorporated by reference to Exhibit 10.26 to the
              Company's Form 10-K for the fiscal year ended December 31, 1994).
     
     10.22  - Letter Agreement between the Company and Barry M. Bloom, dated
              January 12, 1994 (incorporated by reference to Exhibit 10.25 to
              the Company's Form 10-K for the fiscal year ended December 31,
              1993).
     
     10.23  - Collaborative Research Agreement between the Company and Pfizer
              Inc, dated as of July 1, 1994 (incorporated by reference to
              Exhibit 10.1 to the Company's Form 10-Q for the quarterly period
              ended June 30, 1994).
     
     10.24  - Stock Purchase Agreement between the Company and Pfizer dated as
              of July 1, 1994 (incorporated by reference to Exhibit 10.2 to the
              Company's Form 10-Q for the quarterly period ended June 30, 1994).
     
     10.25  - Registration Rights and Standstill Agreement Among Neurogen
              Corporation and the Persons and Entities listed on Schedule I
              thereto, dated as of July 11, 1994 (incorporated by reference to
              Exhibit 10.29 to the Company's Form 10-Q for the quarterly period
              ended September 30, 1994).
     
     10.26  - Collaboration and License Agreement between the Company and
              Schering Corporation and Schering-Plough Ltd. dated as of June 28,
              1995 (incorporated by reference to Exhibit 10.1 to the Company's
              Form 8-K dated July 28, 1995 and subject to a request for
              Confidential Treatment).
     
     11.1  -  Computation of Income (Loss) per Common Share.
     
     27.1  -  Financial Data Schedule.

                                      17

<PAGE>
 
                                                                    EXHIBIT 11.1

<TABLE> 
<CAPTION> 
                             NEUROGEN CORPORATION
                 COMPUTATION OF INCOME (LOSS) PER COMMON SHARE
         (in thousands, except Income (Loss) per Common Share amounts)

                       Three Months Three Months  Six Months    Six Months
                           Ended        Ended       Ended          Ended
                      June 30, 1995 June 30, 1994 June 30, 1995 June 30, 1994
                       (Unaudited)   (Unaudited)  (Unaudited)    (Unaudited)
                      ------------- ------------- ------------- -------------
<S>                   <C>           <C>           <C>           <C> 
Primary:

Weighted average
 shares of common
 stock outstanding      10,105          8,974        10,094         8,972

Dilutive effect of:
  Warrants(1)               37              -            36             -
  Stock options(1)       1,030              -           828             -
                      --------       --------      --------       -------   
Common and common
 equivalent shares      11,172          8,974        10,958         8,972
                      ========       ========      ========       =======    

Net income (loss)     $ 12,234       $ (1,588)     $ 10,534       $(3,565)
                      ========       ========      ========       =======    

Earnings (loss) per
 common and common
 equivalent shares
 (1)                  $   1.10       $  (0.18)     $   0.96       $ (0.40)
                      ========       ========      ========       =======    
Fully diluted:

Weighted average
 shares of common
 stock outstanding      10,105          8,974        10,094         8,972

Dilutive effect of:
  Warrants(1)               40              -            39             -
  Stock Options(1)       1,256              -         1,248             -

Common and common
 equivalent shares      11,401          8,974        11,381         8,972
                      ========       ========      ========       =======

Net income (loss)     $ 12,234       $ (1,588)     $ 10,534       $(3,565)
                      ========       ========      ========       =======

Earnings per common 
 and common equiva-
 lent shares (1)      $   1.07       $      -      $   0.93       $     -
                      ========       ========      ========       =======
</TABLE> 

(1) The common stock equivalents have not been included in periods with losses 
    as their inclusion would be antidilutive.
 

<TABLE> <S> <C>

<PAGE>
<ARTICLE> 5
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1995
<PERIOD-START>                             JAN-01-1995
<PERIOD-END>                               JUN-30-1995
<CASH>                                        24246293
<SECURITIES>                                   5697547
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                              30277305
<PP&E>                                        11905747
<DEPRECIATION>                                 1750161
<TOTAL-ASSETS>                                40639337
<CURRENT-LIABILITIES>                          5071944
<BONDS>                                              0
<COMMON>                                        253203
                                0
                                          0
<OTHER-SE>                                    34709139
<TOTAL-LIABILITY-AND-EQUITY>                  40639337
<SALES>                                              0
<TOTAL-REVENUES>                              17739333
<CGS>                                                0
<TOTAL-COSTS>                                  7395993
<OTHER-EXPENSES>                              (417474)
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                               35996
<INCOME-PRETAX>                               10760814
<INCOME-TAX>                                    227000
<INCOME-CONTINUING>                           10533814
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                  10533814
<EPS-PRIMARY>                                      .96
<EPS-DILUTED>                                      .93
        

</TABLE>


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