NEUROGEN CORP
10-Q, 1996-05-15
PHARMACEUTICAL PREPARATIONS
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<PAGE>
 
                       SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C.  20549
                                        
                                   FORM 10-Q

             [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934
                 For the quarterly period ended March 31, 1996
                                       OR
            [_] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                         Commission File Number 0-18311


                              NEUROGEN CORPORATION
             (Exact name of registrant as specified in its charter)

              Delaware                                22-2845714
    (State or other jurisdiction of                (I.R.S. Employer
    incorporation or organization)                Identification No.)

       35 Northeast Industrial Road
          Branford, Connecticut                           06405
(Address of principal executive offices)                (Zip Code)

                                 (203) 488-8201
              (Registrant's telephone number, including area code)

  Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

                    Yes  X            No
                        ---              ---


  As of May 15, 1996, the registrant had 14,151,116 shares of Common Stock
outstanding.
<PAGE>
 
                              NEUROGEN CORPORATION

                                     INDEX


                                                                        Page
                                                                       Number
                                                                       ------

                        Part I - Financial Information

Item 1.    Financial Statements......................................     1
                                                                         
           Balance Sheets at March 31, 1996 and                          
             December 31, 1995.......................................    1,2
           Statements of Operations for the three-month periods ended    
             March 31, 1996 and 1995.................................     3
           Statements of Cash Flows for the three-month periods ended    
             March 31, 1996 and 1995.................................     4
           Notes to Financial Statements.............................     5
 
Item 2.    Management's Discussion and Analysis of Financial Condition
           and Results of Operations.................................    6-10


                          Part II - Other Information
 
Item 1.    Legal Proceedings.........................................    11
                                                                    
Item 2.    Changes in Securities.....................................    11
                                                                    
Item 3.    Defaults upon Senior Securities...........................    11
                                                                    
Item 4.    Submission of Matters to a Vote of Security Holders.......    11
                                                                    
Item 5.    Other Information.........................................    11
                                                                    
Item 6.    Exhibits and Reports on Form 8-K..........................    11
                                                                    
Signature............................................................    13
 
Exhibit Index........................................................   14-16

                                       i
<PAGE>

                        Part I - Financial Information

Item 1 - Financial Statements

                             Neurogen Corporation
                                Balance Sheets


<TABLE> 
<CAPTION> 
                                               March 31,        December 31,
                                                 1996               1995
                                             (Unaudited)         (Audited)
                                            -------------     -------------
<S>                                         <C>               <C> 
               Assets
Current assets:
  Cash and cash equivalents                 $  32,050,052     $  26,004,548
  Marketable securities                        59,031,124        39,881,172
  Receivables from corporate partner              903,000                 -
  Other current assets                          1,205,075         1,517,543
                                            -------------     -------------

    Total current assets                       93,189,251        67,403,263

Marketable securities - long term                                25,731,798

Property, plant & equipment:
  Land                                            425,000           425,000
  Building                                      8,417,046         8,415,766
  Equipment                                     4,623,366         4,071,650
  Furniture                                       174,261           166,072
  Construction in progress                        410,725           293,911
                                            -------------     -------------
                                               14,050,398        13,372,399
  Less accumulated depreciation                 2,359,272         2,146,482
                                            -------------     -------------

    Net property, plant and equipment          11,691,126        11,225,917
Other assets, net                                 451,013           495,384
                                            -------------     -------------
                                            $ 105,331,390     $ 104,856,362
                                            =============     =============
</TABLE> 

See accompanying notes to financial statements.


                                       1
<PAGE>

                             Neurogen Corporation
                                Balance Sheets

<TABLE> 
<CAPTION> 
                                                                    March 31,               December 31,
                                                                      1996                      1995
                                                                   (Unaudited)               (Audited)
                                                                ----------------         -----------------
<S>                                                             <C>                      <C> 
           Liabilities & Stockholders' Equity

 Current Liabilities:
   Accrued expenses                                             $      1,032,166         $       1,997,647
   Unearned revenue from corporate partners                            1,494,667                 4,100,000
   Current portion of mortgage payable                                   164,858                   159,812
                                                                ----------------         -----------------

     Total current liabilities                                         2,691,691                 6,257,459

 Mortgage payable, excluding current portion                             416,919                   460,075
 Other compensation                                                       62,587                    62,587
                                                                ----------------         -----------------

     Total liabilities                                                 3,171,197                 6,780,121

 Stockholders' Equity:
   Preferred stock, par value $.025 per share.
      Authorized 2,000,000 shares; none issued                                -                          -
   Common stock, par value $.025 per share.
      Authorized 30,000,000 shares; issued and outstanding
      14,057,759 shares at March 31, 1996 and
      13,949,064 shares at December 31, 1995                             351,444                   348,727
   Additional paid-in capital                                        106,720,864               106,039,959
   Accumulated deficit                                                (4,802,645)               (8,412,660)
   Unrealized gain (loss) on marketable securities                      (109,470)                  100,215
                                                                ----------------         -----------------

     Total stockholders' equity                                      102,160,193                98,076,241
                                                                ----------------         -----------------

                                                                $    105,331,390         $     104,856,362
                                                                =================        =================
</TABLE> 

 See accompanying notes to financial statements.

                                                       2
<PAGE>

                             Neurogen Corporation
               Statements of Operations and Accumulated Deficit



<TABLE> 
<CAPTION> 
                                                  Three Months     Three Months
                                                     Ended            Ended
                                                 March 31, 1996   March 31, 1995
                                                   (Unaudited)      (Unaudited)
                                                 --------------   --------------
<S>                                              <C>              <C> 
Operating revenues:                                               
    Research                                       $ 3,244,667     $ 1,869,667
    License fees                                     3,000,000               -
                                                   -----------     -----------  
      Total operating revenues                       6,244,667       1,869,667
                                                                    
                                                                    
Operating expenses:                                                 
  Research and development                           3,051,524       3,043,972
  General and administrative                           748,196         688,432
                                                   -----------     -----------  
    Total operating expenses                         3,799,720       3,732,404
                                                                    
Other income (expense):                                             
  Investment income                                  1,249,491         180,375
  Interest expense                                     (14,423)        (18,099)
                                                   -----------     -----------  
    Total other income, net                          1,235,068         162,276
                                                   -----------     -----------  
                                                                    
Income (loss) before provision for income taxes      3,680,015      (1,700,461)
Provision for income taxes                              70,000               -
                                                   -----------     -----------  
Net income (loss)                                    3,610,015      (1,700,461)
                                                   ===========     ===========  
                                                                    
Earnings (loss) per share                          $       .23     $      (.17)
                                                   ===========     ===========  
                                                                    
Shares used to compute earnings (loss) per share    15,547,000      10,084,000
                                                   -----------     -----------  
</TABLE> 

  See accompanying notes to financial statements.

                                       3
<PAGE>

                             Neurogen Corporation
                           Statements of Cash Flows

<TABLE> 
<CAPTION> 
                                                                               Three Months        Three Months
                                                                             Ended March 31,      Ended March 31,
                                                                                   1996                1995
                                                                               (Unaudited)          (Unaudited)
                                                                             ---------------      ---------------
<S>                                                                          <C>                  <C> 
Cash flows from operating activities:
  Net income (loss)                                                          $    3,610,015       $  (1,700,461)
  Adjustments to reconcile net income (loss)
    to net cash provided by (used in) operating
    activities:
    Depreciation and amortization expense                                           216,887             202,264
    Net gain on sale of assets                                                            -              (4,375)
  Changes in operating assets and liabilities:
    Decrease in accrued expenses                                                   (965,481)           (410,977)
    Increase (decrease) in unearned revenue from corporate partner               (2,605,333)            719,666
    Decrease in other current assets                                                312,468              99,109
    Increase in receivable from corporate partners                                 (903,000)                  -
    (Increase) decrease in other assets, net                                         40,274              (9,022)
                                                                             --------------       -------------
       Net cash used in operating
         activities                                                                (294,170)         (1,103,796)

Cash flows from investing activities:
    Purchase of plant and equipment                                                (677,999)           (370,012)
    Purchases of marketable securities                                           (3,069,953)          (4,116,343)
    Maturities and sales of marketable securities                                 9,442,114           3,978,444
                                                                             --------------       -------------

      Net cash provided by (used in) investing activities                         5,694,162            (507,911)

Cash flows from financing activities:
  Exercise of employee stock options                                                683,622              73,898
  Principal payments under mortgage payable                                         (38,110)            (33,654)
  Principal payments under capital lease obligations                                      -             (30,863)
                                                                             --------------       -------------
    Net cash provided by financing
      activities                                                                    645,512               9,381
                                                                             --------------       -------------

     Net increase (decrease) in cash and cash equivalents                         6,045,504          (1,602,326)

Cash and cash equivalents at beginning of period                                 26,004,548           9,439,727
                                                                             --------------       -------------

Cash and cash equivalents at end of period                                   $   32,050,052       $   7,837,401
                                                                             ==============       =============
</TABLE> 

See accompanying notes to financial statements.

                                       4
<PAGE>
 
NEUROGEN CORPORATION
                         NOTES TO FINANCIAL STATEMENTS
                                 MARCH 31, 1996
                                  (UNAUDITED)



(1)  Basis of Presentation and Summary of Significant Accounting Policies
     ---------------------------------------------------------------------

     The unaudited financial statements have been prepared from the books and
     records of Neurogen Corporation (the "Company") in accordance with
     generally accepted accounting principles for interim financial information
     pursuant to Rule 10-01 of Regulation S-X. Accordingly, they do not include
     all of the information and footnotes required by generally accepted
     accounting principles for complete financial statements. In the opinion of
     management, all adjustments (consisting of normal recurring accruals)
     considered necessary for a fair presentation have been included. Interim
     results are not necessarily indicative of the results that may be expected
     for the fiscal year.

(2)  Marketable Securities
     ---------------------
 
     Marketable securities consist principally of debt securities with
     maturities of three months to five years and have been classified as
     available for sale securities. Management considers these investments,
     which represent funds available for current operations, an integral
     component of its cash management activities. Accordingly, marketable
     securities have been classified as current assets in the March 31, 1996
     balance sheet.

(3)  Adoption of New Accounting Pronouncements
     -----------------------------------------

     The Company had adopted Statement of Financial Accounting Standards No. 121
     ("SFAS 121"), "Accounting for the Impairment of Long-Lived Assets and for
     Long-Lived Assets to be Disposed Of".  SFAS 121 requires impairment losses
     to be recorded on the long-lived assets used in operations when indicators
     of impairment are present and the undiscounted cash flows estimated to be
     generated by those assets are less than the assets' carrying amount.  SFAS
     121 also addresses the accounting for any expected disposal of long-lived
     assets. The adoption of SFAS 121 has no impact on the financial position or
     results of operations of the Company as no indicators of impairment
     currently exist.

     The Company has adopted the disclosure provisions of Financial Accounting
     Standards No. 123 ("SFAS 123"), Accounting and Disclosure of Stock-Based
     Compensation.  The Company will continue to account for its stock-based
     compensation arrangements under the provisions of APB 25, Accounting for
     Stock Issued to Employees.

                                       5
<PAGE>
 
ITEM 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF
         FINANCIAL CONDITION AND RESULTS OF OPERATIONS

       Since its inception in September 1987, Neurogen has been engaged in the
     discovery and development of drugs.  The Company has not derived any
     revenue from product sales and, excluding the effect of license fees
     received from Schering-Plough Corporation ("Schering-Plough") in 1995 and
     1996 and Pfizer Inc ("Pfizer") in 1995, expects to incur significant losses
     in most years prior to deriving any product revenues.  Its revenues to date
     have come from three collaborative research agreements entered into with
     Pfizer, one collaboration with Schering-Plough, and from interest income.

     RESULTS OF OPERATIONS
 
       Results of operations may vary from period to period depending on
     numerous factors, including the timing of income earned under existing or
     future strategic alliances, joint ventures or financings, if any, the
     progress of the Company's research and development projects, technological
     advances and determinations as to the commercial potential of proposed
     products.  Neurogen expects research and development costs to increase
     significantly over the next several years as its drug development programs
     progress.  In addition, general and administrative expenses necessary to
     support the expanded research and development activities are expected to
     increase for the foreseeable future.

       The Company's operating revenues increased to $6.2 million for the three
     months ended March 31, 1996 from $1.9 million for the same period in 1995.
     The Company's 1996 first quarter results include previously unearned
     license revenue of $3 million received from Schering-Plough in July 1995
     for access to a portion of Neurogen's combinatorial chemistry libraries.
     Research revenues increased $1.4 million, or 74 percent, to $3.2 million
     due to the commencement of research funding under the Schering-Plough
     Agreement(as defined below) and the 1995 Pfizer Agreement (as defined
     below) in July 1995 and November 1995, respectively.

       Research and development costs remained flat for the three-month period
     ended March 31, 1996 as compared to the same period in 1995.   The
     assumption of development costs by Pfizer and Schering-Plough, pursuant to
     the Company's collaborative agreements, generally offset an increase in the
     size of the Company's research staff and Neurogen's additional funding of
     its drug development portfolio.  Research and development costs represented
     80 percent of total operating expenses for the first quarter of 1996 as
     compared to 82 percent for the same period in 1995.

       General and administrative expenses increased 9 percent to $748,196 for
     the three-month period ended March 31, 1996 as compared to the same period
     in 1995.  This increase is due primarily to an increase in administrative
     activities and the addition of related facilities to support the Company's
     expanded research programs.

                                       6
<PAGE>
 
       Other income consisting primarily of interest income, and gains and
     losses from invested cash and marketable securities increased to $1.2
     million for the first quarter of 1996 from $162,000 for the same period in
     1995 due to a higher level of invested funds.

       The Company recognized net income of $3.6 million for the three months
     ended March 31, 1996 as compared with a net loss of $1.7 million for the
     same period in 1995.  The change in earnings is primarily due to the
     recognition of the $3 million license fee and the increase in research
     revenues, each as noted above.

       In 1994, the Company adopted Financial Accounting Standards Board
     Statement No. 115, "Accounting for Certain Investments in Debt and Equity
     Securities" ("SFAS 115").  Adoption of SFAS 115 did not have a significant
     impact on the Company's financial statements.

       The Financial Accounting Standards Board recently issued Statement of
     Financial Accounting Standards No. 123, "Accounting for Stock-Based
     Compensation" ("SFAS 123").  SFAS 123 permits either the recording of the
     expense of stock-based compensation over the service period or disclosing
     in the footnotes to the financial statement the pro forma effects on net
     income and on earnings per share.  SFAS 123 will be effective for 1996.
     The Company is evaluating the effect of this statement.

     LIQUIDITY AND CAPITAL RESOURCES
 
       At March 31, 1996 and December 31, 1995, cash, cash equivalents and
     marketable securities were in the aggregate $91.1 million and $91.6 million
     respectively.  While the Company's aggregate level of cash, cash
     equivalents and marketable securities did not change significantly during
     the first quarter of 1996, these levels have fluctuated significantly in
     the past and are expected to do so in the future as a result of the factors
     described below.

       Neurogen's cash requirements to date have been met by the proceeds of its
     financing activities, amounts received pursuant to collaborative
     arrangements and interest earned on invested funds.  The Company's
     financing activities include three private placement offerings of its
     common stock prior to its initial public offering, underwritten public
     offerings of the Company's common stock in 1989, 1991 and 1995, and the
     private sale of common stock to Pfizer in connection with entering into the
     Pfizer Agreements.  Total funding received from these financing activities
     was approximately $104.9 million. The Company's expenditures have been
     primarily to fund research and development and general and administrative
     expenses and to construct and equip its research and development facility.

       In the first quarter of 1992, the Company and Pfizer entered into a
     collaborative agreement to develop drugs which modulate the
     neurotransmitter GABA to treat anxiety disorders and cognition impairment
     (the "1992 Pfizer Agreement") pursuant to which Pfizer made a $13.8 million
     equity investment in the Company. Under this agreement, the Company has
     received or is scheduled to receive $4.6 million in each year from 1992
     through 1996 to fund Neurogen's 

                                       7
<PAGE>
 
     research in its anxiolytic (anxiety-reducing drugs) and cognitive enhancer
     programs. Neurogen could also receive milestone payments of up to $12.5
     million during the development and regulatory approval of its anxiolytic
     and cognition enhancement products. In return, Pfizer received the
     exclusive rights to manufacture and market collaboration anxiolytics and
     cognition enhancers that act through the family of receptors which interact
     with the neuro-transmitter gama-aminobutyric acid, or GABA, and for which
     it will pay Neurogen royalties based upon net sales levels, if any, for
     such products. As of March 31, 1996, Pfizer had provided $19.6 million of
     research funding to the Company pursuant to the 1992 Pfizer Agreement, in
     addition to its $13.8 million equity investment in 1992.

       Neurogen and Pfizer entered into their second collaborative agreement
     (the "1994 Pfizer Agreement") in July 1994. Under this agreement, Pfizer
     made an additional $9.9 million equity investment in the Company.
     Additionally, the Company has received or is scheduled to receive
     approximately $7.4 million during the three-year period which commenced
     July 1, 1994, to fund Neurogen's  sleep disorder program and may receive up
     to an additional $2.4 million for a fourth year should Pfizer exercise its
     option to extend the research program under the collaboration.  Neurogen
     could also receive milestone payments of up to $3.3 million during the
     development and regulatory approval of its sleep disorder compounds.  As
     part of this second collaboration, Pfizer received the exclusive rights to
     manufacture and market GABA-based sleep disorder products for which it will
     pay Neurogen royalties depending upon net sales levels, if any.  As of
     March 31, 1996, Pfizer had provided $5.0 million of research funding to the
     Company (including $600,000 in unearned revenues) pursuant to the 1994
     Pfizer Agreement, in addition to its $9.9 million equity investment in
     1994.

       Under both the 1992 Pfizer Agreement and the 1994 Pfizer Agreement, in
     addition to making the equity investments and  the research and milestone
     payments noted above, Pfizer is responsible for funding the cost of all
     clinical development and the manufacturing and marketing, if any, of drugs
     developed from the collaborations.

       Neurogen and Pfizer entered into their third collaborative agreement (the
     "1995 Pfizer Agreement") in November 1995 to develop drugs which modulate
     the neurotransmitter neuropeptide Y (NPY) to treat disorders, including
     obesity.  Under this Agreement,  Pfizer made an additional $16.5 million
     equity investment in the Company and paid a $3.5 million license fee.  The
     Company has received or is scheduled to receive approximately $7.2 million
     during the three-year period which commenced November 1, 1995, to fund
     Neurogen's NPY program and may receive up to an additional $2.4 million per
     year for a fourth and fifth year should Pfizer exercise its option to
     extend the research program under the collaboration.  Neurogen could also
     receive milestone payments of up to approximately $28 million during the
     development and regulatory approval of products under the collaboration.
     As of March 31, 1996, Pfizer had provided $600,000 in research funding
     pursuant to the 1995 Pfizer 

                                       8
<PAGE>
 
     Agreement. As part of this third collaboration, Pfizer received the
     exclusive worldwide rights to manufacture and market NPY-based
     collaboration compounds, subject to certain rights retained by Neurogen.
     Pursuant to the 1995 Pfizer Agreement, Neurogen will fund a minority share
     of early stage development costs. In this agreement Neurogen has retained
     the right to manufacture any collaboration products in NAFTA countries and
     has retained a profit sharing option with respect to product sales in NAFTA
     countries. If Neurogen exercises the profit sharing option, it will fund a
     portion of the cost of late stage clinical trials and marketing costs and
     in return receive a specified percentage of any profit generated by sales
     of collaboration products in NAFTA countries. If Neurogen chooses not to
     exercise its profit-sharing option, Pfizer would pay Neurogen royalties on
     drugs marketed in NAFTA countries and would fund a majority of early stage
     and all late stage development and marketing expenses. In either case
     Neurogen would be entitled to royalties on drugs marketed in non-NAFTA
     countries.

       In June 1995, Neurogen and Schering-Plough entered into an agreement (the
     "Schering-Plough Agreement") to collaborate in the discovery and
     development of drugs for the treatment of schizophrenia and other disorders
     which act through the dopamine family of receptors.  Pursuant to the
     Schering-Plough Agreement, the Company received one-time license fees of
     $14 million for rights relating to Neurogen's dopamine program and $3
     million for the right to test certain of Neurogen's combinatorial chemistry
     libraries in selected non-CNS assays.  Schering-Plough also agreed to pay
     an additional $3 million in 1996 for the right to test additional
     libraries.  Neurogen expects to receive approximately $7.2 million during
     the two-year period which commenced June 28, 1995, for research and
     development funding of the Company's dopamine program.  The Company may
     receive additional research and development funding of up to $3.6 million
     per year for three additional one-year periods depending on whether and the
     extent to which Schering-Plough exercises its right to extend the research
     program under the collaboration.  Neurogen could also receive milestone
     payments of up to approximately $32 million if certain development and
     regulatory objectives are achieved regarding its  products subject to the
     collaboration.  In return, Schering-Plough received the exclusive worldwide
     license to market products subject to the collaboration and Neurogen
     retained the rights to receive royalties based on net sales levels, if any,
     and an option to manufacture products for the United States market.   As of
     March 31, 1996, Schering-Plough had provided $3.6 million in research
     funding (including $900,000 in unearned revenue) pursuant to the Schering-
     Plough Agreement.  In addition to the payments described above, Schering-
     Plough is responsible for funding the cost of all clinical development and
     marketing, if any, of drugs subject to the collaboration.

       The Company plans to use its cash balance for its research and
     development activities, working capital and general corporate purposes.
     Neurogen anticipates that its current cash balance, as supplemented by
     research funding pursuant to the Pfizer Agreements and the Schering-Plough
     Agreement, will be sufficient to fund its current and planned operations
     through 1999.  However, Neurogen's funding requirements may change and will
     depend upon numerous factors, including but not limited to, the progress of
     the Company's research and development programs, the timing and results of
     preclinical testing and clinical studies, the timing of regulatory
     approvals, technological advances, determinations as to the commercial
     potential of its proposed products, 

                                       9
<PAGE>
 
     the status of competitive products and the ability of the Company to
     establish and maintain collaborative arrangements with others for the
     purpose of funding certain research and development programs, conducting
     clinical studies, obtaining regulatory approvals and, if such approvals are
     obtained, manufacturing and marketing products. The Company anticipates
     that it may augment its cash balance through financing transactions,
     including the issuance of debt or equity securities and further corporate
     alliances. No arrangements have been entered into for any future financing
     and no assurances can be given that adequate levels of additional funding
     can be obtained on favorable terms, if at all.

       As of December 31, 1995, the Company had approximately $12,240,000 of net
     operating loss carryforwards available for federal income tax purposes
     which expire from the years 2003 through 2009.  The Company had
     approximately $10,670,000 of Connecticut state tax net operating loss
     carryforwards as of December 31, 1995 which expire in the years 1996
     through 1999.  Because of "change in ownership" provisions of the Tax
     Reform Act of 1986, the Company's utilization of its net operating loss
     carryforwards may be subject to an annual limitation in future periods.

                                       10
<PAGE>
 
PART II - OTHER INFORMATION



ITEM 1.  LEGAL PROCEEDINGS

       Not applicable for the first quarter ended March 31, 1996.


ITEM 2.  CHANGES IN SECURITIES

       Not applicable for the first quarter ended March 31, 1996.


ITEM 3.  DEFAULTS UPON SENIOR SECURITIES

       Not applicable for the first quarter ended March 31, 1996.


ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

       Not applicable for the first quarter ended March 31, 1996.


ITEM 5.  OTHER INFORMATION

       Not applicable for the first quarter ended March 31, 1996.


ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

      (a) See Exhibit Index on page 11.
 
      (b) Exhibits and Reports on Form 8-K

      The Company filed a Current Report on Form 8-K on March 27, 1996 to submit
for filing (confidential treatment requested) certain contracts relating to its
recent collaboration with Pfizer Inc to develop drugs which work through
neuropeptide Y to treat disorders such as obesity with the 10-K.

On April 25,1996 a Current Report on Form 8-K was filed disclosing a change in
the Company's auditors.

SAFE HARBOR STATEMENT

Statements which are not historical facts, including statements about the
Company's confidence and strategies, the status of various product development
programs, the sufficiency of cash to fund planned operations and the Company's
expectations concerning its development compounds, drug discovery technologies
and opportunities in the pharmaceutical marketplace are "forward looking
statements" within the meaning of the Private Securities Litigations Reform Act
of 1995 that involve risks and uncertainties and are not guarantees of future
performance.  These risks include, but are not limited to, difficulties or
delays in development, testing, regulatory approval, production and marketing of
any of the Company's drug candidates, the failure to attract or retain
scientific 

                                       11
<PAGE>
 
management personnel, any unexpected adverse side effects or inadequate
therapeutic efficacy of the Company's drug candidates which could slow or
prevent product development efforts, competition within the Company's
anticipated product markets, the Company's dependence on corporate partners with
respect to research and development funding, regulatory filings and
manufacturing and marketing expertise, the uncertainty of product development in
the pharmaceutical industry, inability to obtain sufficient funds through future
collaborative arrangements, equity or debt financings or other sources to
continue the operation of the Company's business, risk that patents and
confidentiality agreements will not adequately protect the Company's
intellectual property or trade secrets, dependence upon third parties for the
manufacture of potential products, inexperience in manufacturing and lack of
internal manufacturing capabilities, dependence on third parties to market
potential products, lack of sales and marketing capabilities, potential
unavailability or inadequacy of medical insurance or other third-party
reimbursement for the cost of purchases of the Company's products, and other
risks detailed in the Company's Securities and Exchange Commission filings,
including its Annual Report on Form 10-K for the year ended December 31, 1995,
each of which could adversely affect the Company's business and the accuracy of
the forward-looking statements contained herein.

                                       12
<PAGE>
 
                                   Signature



     Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.


                                      NEUROGEN CORPORATION



                                      By: /s/ STEPHEN R. DAVIS
                                         -----------------------
                                         Stephen R. Davis
                                         Vice President-Finance and
                                         Chief Financial Officer


Date:  May 15, 1996

                                       13
<PAGE>
 
                                 Exhibit Index
                                 -------------

     Exhibit
     -------
     Number
     ------
     10.1   -    Neurogen Corporation Stock Option Plan, as amended
                 (incorporated by reference to Exhibit 10.1 to the Company's
                 Form 10-K for the fiscal year ended December 31, 1991).

     10.2   -    Form of Stock Option Agreement currently used in connection
                 with the grant of options under Neurogen Corporation Stock
                 Option Plan (incorporated by reference to Exhibit 10.2 to the
                 Company's Form 10-K for the fiscal year ended December 31,
                 1992).

     10.3   -    Neurogen Corporation 1993 Omnibus Incentive Plan, as amended
                 (incorporated by reference to Exhibit 10.3 to the Company's
                 Form 10-K for the fiscal year ended December 31, 1993).

     10.4   -    Form of Stock Option Agreement currently used in connection
                 with the grant of options under Neurogen Corporation 1993
                 Omnibus Incentive Plan (incorporated by reference to Exhibit
                 10.4 to the Company's Form 10-K for the fiscal year ended
                 December 31, 1993).

     10.5   -    Neurogen Corporation 1993 Non-Employee Directors Stock Option
                 Program (incorporated by reference to Exhibit 10.5 to the
                 Company's Form 10-K for the fiscal year ended December 31,
                 1993).

     10.6   -    Form of Stock Option Agreement currently used in connection
                 with the grant of options under Neurogen Corporation 1993 Non-
                 Employee Directors Stock Option Program (incorporated by
                 reference to Exhibit 10.6 to the Company's Form 10-K for the
                 fiscal year ended December 31, 1993).

     10.7   -    Employment Contract between the Company and Harry H. Penner,
                 Jr., dated as of October 12, 1993 (incorporated by reference to
                 Exhibit 10.7  to the Company's Form 10-K for the fiscal year
                 ended December 31, 1993).

     10.8   -    Employment Contract between the Company and John F. Tallman,
                 dated as of December 1, 1993 (incorporated by reference to
                 Exhibit 10.25 to the Company's Form 10-Q for the quarterly
                 period ended September 30, 1994).

     10.9   -    Open-End Mortgage Deed and Security Agreement between the
                 Company and Orion Machinery & Engineering Corp., dated March
                 16, 1989 (incorporated by reference to Exhibit 10.15 to
                 Registration Statement  No. 33-29709 on Form S-1).

     10.10  -    Form of Proprietary Information and Inventions Agreement
                 (incorporated by reference to Exhibit 10.31 to Registration
                 Statement No. 33-29709 on Form S-1).

                                       14
<PAGE>
 
     10.11  -    Warrant to Purchase 47,058 Shares of Common Stock to MMC/GATX
                 Partnership No. I, dated February 20, 1991 (incorporated by
                 reference to Exhibit 10.34 to the Company's Form 10-K for the
                 fiscal year ended December 31, 1990).

     10.12  -    Collaborative Research Agreement  and License and Royalty
                 Agreement between the Company and Pfizer Inc, dated as of
                 January 1, 1992 (confidential treatment requested)
                 (incorporated by reference to Exhibit 10.35 to the Company's
                 Form 10-K for the fiscal year ended December 31, 1991).

     10.13  -    License Agreement between the Company and the National
                 Technical Information Service, dated as of January 1, 1992
                 (incorporated by reference to Exhibit 10.36 to the Company's
                 Form 10-K for the fiscal year ended December 31, 1991).

     10.14  -    Cooperative Research and Development Agreement between the
                 Company and the National Institutes of Health, dated as of
                 January 21, 1993 (incorporated by reference to Exhibit 10.37 to
                 the Company's Form 10-K for the fiscal year ended December 31,
                 1991).

     10.15  -    Letter Agreement between the Company and Barry M. Bloom, dated
                 January 12, 1994 (incorporated by reference to Exhibit 10.25 to
                 the Company's Form 10-K for the fiscal year ended December 31,
                 1993).

     10.16  -    Letter Agreement between the Company and Robert H. Roth, dated
                 April 14, 1994 (incorporated by reference to Exhibit 10.26 to
                 the Company's Form 10-K for the fiscal year ended December 31,
                 1994).

     10.17  -    Collaborative Research Agreement and License and Royalty
                 Agreement between the Company and Pfizer Inc, dated as of July
                 1, 1994 (confidential treatment requested) (incorporated by
                 reference of Exhibit 10.1 to the Company's Form 10-Q for the
                 quarterly period ended June 30, 1994).

     10.18  -    Stock Purchase Agreement between the Company and Pfizer dated
                 as of July 1, 1994 (incorporated by reference to Exhibit 10.2
                 to the Company's Form 10-Q for the quarterly period ended June
                 30, 1994).

     10.19  -    Registration Rights and Standstill Agreement among the Company
                 and the Persons and Entities listed on Schedule I thereto,
                 dated as of July 11, 1994 (incorporated by reference to Exhibit
                 10.29 to the Company's Form 10-Q for the quarterly period ended
                 September 30, 1994).

     10.20  -    Collaboration and License Agreement and Screening Agreement
                 between the Company and Schering-Plough Corporation
                 (confidential treatment requested) (incorporated by reference
                 to Exhibit 10.1 to the Company's Form 8-K dated July 28, 1995).

                                       15
<PAGE>
 
     10.21  -    Lease Agreement between the Company and Commercial Building
                 Associates dated as of August 30, 1995 (incorporated by
                 reference to Exhibit 10.27 to the Company's Form 10-Q for the
                 quarterly period ended September 30, 1995).

     10.22  -    Collaborative Research Agreement between the Company and
                 Pfizer dated as of November 1, 1995 (confidential treatment
                 requested) (incorporated by reference to Exhibit 10.1 of the
                 Company's Form 8-K dated November 1, 1995).

     10.23       Development and Commercialization Agreement between the
                 Company and Pfizer dated as of November 1, 1995 (confidential
                 treatment requested) (incorporated by reference to Exhibit 10.2
                 of the Company's Form 8-K dated November 1, 1995).

     10.24  -    Stock Purchase Agreement between the Company and Pfizer dated
                 as of November 1, 1995 (incorporated by reference to Exhibit
                 10.3 of the Company's Form 8-K dated November 1, 1995).

     11.1   -    Computation of Earnings per Common Share.
 
     27.1   -    Financial Data Schedule

                                       16

<PAGE>

                                                                    Exhibit 11.1

                             Neurogen Corporation
              Computation of Net Earnings (Loss) Per Common Share
      (in thousands, except Net Earnings (Loss) per Common Share amounts)

<TABLE> 
<CAPTION> 
                                         Three Months         Three Months
                                             Ended               Ended
                                         March 31,1996       March 31,1995
                                          (Unaudited)         (Unaudited)
                                         -------------       --------------
<S>                                      <C>                 <C> 
 Weighted average shares of                                  
   common stock outstanding                    14,020             10,084
                                                             
 Dilutive effect of:                                       
     Warrants (1)                                  43                 -
     Stock options (1)                          1,484                 -
                                           ----------         ----------  
                                                             
 Common and common                                           
   equivalent shares                           15,547             10,084
                                           ==========         ==========  
                                                             
 Net income (loss)                         $    3,610         $   (1,700)
                                           ==========         ==========  
                                                             
 Earnings (loss) per common and                              
   common equivalent shares (1)            $     0.23         $    (0.17)
                                           ==========         ==========  
</TABLE> 


 (1) The common stock equivalents have not been included in periods with losses
     as their inclusion would be antidilutive.

<TABLE> <S> <C>

<PAGE>
 
<ARTICLE> 5
<LEGEND>
THIS SCHEDULE CONTAINS SUMMARY FINANCIAL INFORMATION EXTRACTED FROM NEUROGEN
CORPORATION AND IS QUALIFIED IN ITS ENTIRETY BY REFERENCE TO SUCH FINANCIAL
STATEMENTS.
</LEGEND>
       
<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                          DEC-31-1996
<PERIOD-START>                             JAN-01-1996
<PERIOD-END>                               MAR-31-1996
<CASH>                                      32,050,052
<SECURITIES>                                59,031,124
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                            93,189,251
<PP&E>                                      14,050,398
<DEPRECIATION>                               2,359,272
<TOTAL-ASSETS>                             105,331,390
<CURRENT-LIABILITIES>                        2,691,691
<BONDS>                                              0
                                0
                                          0
<COMMON>                                       351,444
<OTHER-SE>                                   (109,470)
<TOTAL-LIABILITY-AND-EQUITY>               105,331,390
<SALES>                                              0
<TOTAL-REVENUES>                             6,244,667
<CGS>                                                0
<TOTAL-COSTS>                                3,799,720
<OTHER-EXPENSES>                           (1,235,068)
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                              14,423
<INCOME-PRETAX>                              3,680,015
<INCOME-TAX>                                    70,000
<INCOME-CONTINUING>                          3,610,015
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                 3,610,015
<EPS-PRIMARY>                                      .23
<EPS-DILUTED>                                      .23
        

</TABLE>


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