NEUROGEN CORP
10-Q, 1997-08-14
PHARMACEUTICAL PREPARATIONS
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<PAGE>
 
                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                         ----------------------------

                                   FORM 10-Q

             [x]  QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d)
                    OF THE SECURITIES EXCHANGE ACT OF 1934
                 For the quarterly period ended June 30, 1997

                                      OR

            [ ]  TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d)
                    OF THE SECURITIES EXCHANGE ACT OF 1934

                        Commission File Number 0-18311

                             NEUROGEN CORPORATION
            (Exact name of registrant as specified in its charter)

         Delaware                                                22-2845714
(State or other jurisdiction of                               (I.R.S. Employer
incorporation or organization)                              Identification No.)

     35 Northeast Industrial Road
       Branford, Connecticut                                        06405
(Address of principal executive offices)                         (Zip Code)

                                (203) 488-8201
             (Registrant's telephone number, including area code)

    Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days.

                             Yes    X              No
                                 ------               ------
    As of August 13, 1997 the registrant had 14,355,958 shares of Common Stock
outstanding.
<PAGE>
 
                             NEUROGEN CORPORATION

                                     INDEX

<TABLE> 
<CAPTION> 
                                                                                   Page
                                                                                  Number
                                                                                  ------
                         Part I - Financial Information
<S>          <C>                                                                    <C> 
Item 1.      Financial Statements...................................................   1

               Balance Sheets at June 30, 1997 and
                 December 31, 1996..................................................   1,2
               Statements of Operations for the three-month and six-month
                 periods  ended June 30, 1997 and 1996 .............................   3
               Statements of Cash Flows for the three-month and six-month
                 periods ended June 30, 1997 and 1996 ..............................   4
               Notes to Financial Statements........................................   5

Item 2.      Management's Discussion and Analysis of Financial Condition and.......    Results
of Operations    ..................................................................    6-9

                         Part II - Other Information

Item 1.      Legal Proceedings.....................................................    10

Item 2.      Changes in Securities.................................................    10

Item 3.      Defaults upon Senior Securities.......................................    10

Item 4.      Submission of Matters to a Vote of Security Holders...................    10

Item 5.      Other Information.....................................................    10

Item 6.      Exhibits and Reports on Form 8-K......................................    10

Signature      ....................................................................    12

Exhibit Index  .................................................................... 13-15
</TABLE> 
                                       i
<PAGE>
 
<TABLE> 
<CAPTION> 

                                                  PART I - FINANCIAL INFORMATION

ITEM 1 - FINANCIAL STATEMENTS

                                                       NEUROGEN CORPORATION
                                                          BALANCE SHEETS
                                                          (In thousands)

                                                          JUNE 30,        DECEMBER 31,
                                                            1997              1996
                                                                              ----
                                                        (UNAUDITED)        (AUDITED)
                                                        -----------         --------
                     Assets
<S>                                                 <C>                 <C> 
Current assets:
  Cash and cash equivalents                            $       53,681   $        62,823
  Marketable securities                                        37,091            32,314
  Receivables from corporate partners                             711               460
  Other current assets                                          1,087             1,132
                                                       ---------------   ---------------

    Total current assets                                       92,570            96,729

Property, plant & equipment:
  Land and land improvements                                      523               523
  Building and building improvements                            8,775             8,679
  Leasehold improvements                                        4,026             4,005
  Equipment                                                     7,169             5,903
  Furniture                                                       440               311
  Construction in progress                                      3,913               440
                                                       ---------------   ---------------
                                                               24,846            19,861
  Less accumulated depreciation and amortization                3,916             3,136
                                                       ---------------   ---------------

    Net property, plant and equipment                          20,930            16,725
Other assets, net                                                 373               415
                                                       ===============   ===============
                                                       $      113,873   $       113,869
                                                       ===============   ===============
</TABLE> 

See accompanying notes to financial statements.

                                       1
<PAGE>
 
<TABLE> 
<CAPTION> 


                                                       NEUROGEN CORPORATION
                                                          BALANCE SHEETS
                                               (In thousands, except per share data)

                                                          JUNE 30,        DECEMBER 31,
                                                            1997             1996
                                                                             ----
                                                        (UNAUDITED)        (AUDITED)
                                                         ----------        ---------
       Liabilities & Stockholders' Equity
<S>                                                 <C>                <C> 
Current Liabilities:
  Accounts payable and accrued expenses                $        3,757    $        3,010
  Unearned revenue from corporate partners                        200             4,100
  Current portion of mortgage payable                             193               181
                                                       ---------------   ---------------

    Total current liabilities                                   4,150             7,291

Mortgage payable, excluding current portion                       180               279
Other compensation                                                 54                54
                                                       ---------------   ---------------

    Total liabilities                                           4,384             7,624

Stockholders' Equity:
  Preferred stock, par value $.025 per share.
     Authorized 2,000,000 shares; none issued                       -                 -
  Common stock, par value $.025 per share.
     Authorized 30,000,000 shares; issued and outstanding
     14,353,108 shares at June 30, 1997 and
     14,252,404 shares at December 31, 1996                       359               356
  Additional paid-in capital                                  109,081           108,491
  Retained earnings (deficit)                                      76            (2,519)
  Unrealized loss on marketable securities                        (27)              (83)
                                                       ---------------   ---------------

    Total stockholders' equity                                109,489           106,245
                                                       ---------------   ---------------

                                                       $      113,873    $      113,869
                                                       ===============   ===============
</TABLE> 

See accompanying notes to financial statements.

                                       2
<PAGE>
 
<TABLE> 
<CAPTION> 

                                               Neurogen Corporation
                                              Statements of Operations
                                                    (In thousands)
                                          THREE MONTHS      THREE MONTHS         SIX MONTHS          SIX MONTHS
                                             ENDED             ENDED               ENDED               ENDED
                                         JUNE 30, 1997      JUNE 30, 1996     JUNE 30, 1997       JUNE 30, 1996
                                          (UNAUDITED)       (UNAUDITED)         (UNAUDITED)         (UNAUDITED)
                                           ----------        ----------          ----------          ----------
Operating revenues:
<S>                                  <C>                  <C>               <C>                  <C> 
  License fees                           $           -     $           -      $         3,000     $         3,000
  Research and Development                       3,949             3,945                7,928               7,447
                                         --------------    --------------     ----------------    ----------------
    Total operating revenues                     3,949             3,945               10,928              10,447

Operating Expenses:
  Research and development                       4,505             3,380                8,874               6,690
  General and administrative                       965               643                1,920               1,391
                                         --------------    --------------     ----------------    ----------------
    Total operating expenses                     5,470             4,023               10,794               8,081

                                         --------------    --------------     ----------------    ----------------
      Total operating income (loss)             (1,521)              (78)                 134               2,366

Other income (expense):
  Investment income                              1,276             1,238                2,517               2,488
  Interest expense                                 (10)              (12)                 (21)                (26)
                                         --------------    --------------     ----------------    ----------------
    Total other income, net                      1,266             1,226                2,496               2,462
                                         --------------    --------------     ----------------    ----------------

Income (loss) before provision for 
  income taxes                                    (255)            1,148                2,630               4,828
Provision for income taxes                                            30                   35                 100
                                         ==============    ==============     ================    ================
Net income (loss)                                 (255)            1,118                2,595               4,728
                                         ==============    ==============     ================    ================

Earnings (loss) per share:
    Primary                              $        (0.02)   $         0.07     $           0.17    $           0.30
                                         ==============    ==============     ================    ================

    Fully diluted                        $        (0.02)   $         0.07     $           0.17    $           0.30
                                         ==============    ==============     ================    ================

Shares used in calculation of 
    earnings (loss) per share:
    Primary                                     14,339            15,533               15,345              15,536
                                         ==============    ==============     ================    ================
    Fully diluted                               14,339            15,533               15,447              15,536
                                         ==============    ==============     ================    ================
</TABLE> 

See accompanying notes to financial statements.

                                       3
<PAGE>
 
<TABLE> 
<CAPTION> 


                                                       NEUROGEN CORPORATION
                                                     STATEMENTS OF CASH FLOWS
                                                          (In thousands)

                                                          SIX MONTHS          SIX MONTHS
                                                        ENDED JUNE 30,      ENDED JUNE 30,
                                                             1997                1996
                                                          (UNAUDITED)        (UNAUDITED)
                                                        ----------------    ---------------
<S>                                                   <C>                 <C> 
Cash flows from operating activities:
  Net income                                            $        2,595     $          4,728
  Adjustments to reconcile net income
    to net cash used in operating
    activities:
    Depreciation and amortization expense                           802                  447
    Net gain on sale of assets                                        3                  (16)
  Changes in operating assets and liabilities:

    Increase (decrease) in accounts payable and 
      accrued expenses                                              747                 (775)
    Decrease in unearned revenue from corporate partners         (3,900)                (200)
    Decrease in other current assets                                 45                  422
    Increase in receivable from corporate partners                 (251)              (1,603)
    Decrease in other assets, net                                    32                   61
                                                         --------------      ---------------

       Net cash provided by operating
         activities                                                  73              3,064

Cash flows from investing activities:
    Purchase of plant and equipment                              (5,025)            (1,423)
    Purchases of marketable securities                          (24,383)           (14,235)
    Maturities and sales of marketable securities                19,662             34,519
    Proceeds from sale of asset                                      25                109
                                                        ----------------    ---------------

      Net cash provided by (used in) investing activities        (9,721)            18,970

Cash flows from financing activities:
  Exercise of employee stock options                                593              1,403
  Principal payments under mortgage payable                         (87)               (77)
                                                        -----------------------------------

    Net cash provided by financing
      activities                                                    506              1,326
                                                        ----------------    ---------------


     Net increase (decrease) in cash and cash equivalents        (9,142)            23,360

Cash and cash equivalents at beginning of period                 62,823             26,005
                                                        ----------------    ---------------

Cash and cash equivalents at end of period              $        53,681     $        49,365
                                                        ================    ===============
</TABLE> 

See accompanying notes to financial statements.

                                       4
<PAGE>
 
                             NEUROGEN CORPORATION
                         NOTES TO FINANCIAL STATEMENTS
                                 JUNE 30, 1997
                                  (UNAUDITED)

 (1)    Basis of Presentation and Summary of Significant Accounting Policies
        --------------------------------------------------------------------

        The unaudited financial statements have been prepared from the books and
        records of Neurogen Corporation (the "Company") in accordance with
        generally accepted accounting principles for interim financial
        information pursuant to Rule 10-01 of Regulation S-X. Accordingly, they
        do not include all of the information and footnotes required by
        generally accepted accounting principles for complete financial
        statements. In the opinion of management, all adjustments (consisting of
        normal recurring accruals) considered necessary for a fair presentation
        have been included. Interim results are not necessarily indicative of
        the results that may be expected for the fiscal year.

 (2)    Marketable Securities
        ---------------------

        Marketable securities consist principally of debt securities with
        maturities of three months to five years and have been classified as
        available for sale securities. Management considers these investments,
        which represent funds available for current operations, an integral
        component of its cash management activities. Accordingly, marketable
        securities have been classified as current assets in the balance sheets.

 (3)    Adoption of New Accounting Pronouncements
        -----------------------------------------

        In February 1997, the Financial Accounting Standards Board issued
        Statement No. 128, Earnings per Share, which is required to be adopted
        on December 31, 1997. At that time, the Company will be required to
        change the method currently used to compute earnings per share and to
        restate all prior periods. Under the new requirements for calculating
        primary earnings per share, the dilutive effect of stock options will be
        excluded. The impact is expected to have no change and a $.01 increase
        in primary earnings per share for the second quarter ended June 30, 1997
        and June 30, 1996, respectively. For the six month period ended June 30,
        1997 and June 30, 1996 the impact is expected to have a $ .01 and a $.03
        increase respectively. The impact of Statement 128 on the calculation of
        fully diluted earnings per share for these periods is not expected to be
        material.

 (4)    Reclassifications
        -----------------

        Certain reclassifications have been made to the 1996 financial
        statements in order to conform to the 1997 presentation.

                                       5
<PAGE>
 
ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF
           FINANCIAL CONDITION AND RESULTS OF OPERATIONS

           Since its inception in September 1987, Neurogen has been engaged in
        the discovery and development of drugs. The Company has not derived any
        revenue from product sales and, excluding the effect of one-time license
        fees received in 1996 from Schering-Plough and American Home Products
        and from Schering-Plough and Pfizer in 1995, expects to incur
        significant losses in most years prior to deriving any such product
        revenues. Revenues to date have come from three collaborative research
        agreements entered into with Pfizer, one collaboration with
        Schering-Plough, one license agreement with American Home Products and
        from interest income.

        RESULTS OF OPERATIONS

           Results of operations may vary from period to period depending on
        numerous factors, including the timing of income earned under existing
        or future strategic alliances, joint ventures or financings, if any, the
        progress of the Company's research and development projects,
        technological advances and determinations as to the commercial potential
        of proposed products. Neurogen expects research and development costs to
        increase significantly over the next several years as its drug
        development programs progress. In addition, general and administrative
        expenses necessary to support the expanded research and development
        activities are expected to increase for the foreseeable future.

        THREE MONTHS ENDED JUNE 30, 1997 AND 1996

               The Company's operating revenues remained at $3.9 million for the
        three months ended June 30, 1997 as compared to the same period in 1996.
        Research and development revenues include amounts received from Pfizer
        and Schering-Plough, under separate collaborations, to fund Neurogen's
        collaborative research programs and, in the case of its NPY-obesity
        collaboration with Pfizer, to reimburse Neurogen for certain expenses
        for the clinical development of the Company's lead anti-obesity drug NGD
        95-1.

               Research and development costs increased 33 percent to $4.5
        million for the three-month period ended June 30, 1997 as compared to
        the same period in 1996. The increase is due to increases in research
        and development personnel, an increase in clinical development costs and
        an expansion of Neurogen's AIDD (Accelerated Intelligent Drug Design)
        program. Research and development costs represented 82 percent of total
        operating expenses for the second quarter of 1997 as compared to 84
        percent for the same period in 1996.

               General and administrative expenses increased 50 percent to $1.0
        million for the three-month period ended June 30, 1997 as compared to
        the same period in 1996. This increase is due to an increased level of
        administrative expenses necessary to support a growing research staff.

               Other income consisting primarily of interest income, and gains
        and losses from invested cash and marketable securities remained flat
        for the second quarter of 1997 as compared to the same period in 1996.

               The Company recognized a net loss of $0.26 million for the three
        months ended June 30, 1997 as compared with a net income of $1.1 million
        for the same period in 1996. The decrease in earnings is primarily due
        to the increase in operating expenses for the second quarter of 1997.

        SIX MONTHS ENDED JUNE 30, 1997 AND 1996

               The Company's operating revenues increased to $10.9 million for
        the six months ended June 30, 1997 from $10.4 million for the same
        period in 1996. Research and development revenues increased $0.5
        million, or 6 percent, to $7.9 million. 

                                       6
<PAGE>
 
               Research and development expenses increased 33 percent to $8.9
        million for the six months ended June 30, 1997 as compared to the same
        period in 1996. The increase is due to increases in research and
        development personnel, an increase in clinical development costs and an
        expansion of Neurogen's AIDD (Accelerated Intelligent Drug Design)
        program. Research and development costs represented 82 and 83 percent of
        total operating expenses for each of the six month periods ended June
        30, 1997 and 1996 respectively.

               General and administrative expenses increased 38 percent to $1.9
        million for the six months ended June 30, 1997 as compared to the same
        period in 1996. This increase is due to an increased level of
        administrative expenses necessary to support a growing research staff.

               Other income consisting primarily of interest income, and gains
        and losses from invested cash and marketable securities remained at $2.5
        million for the six months ended June 30, 1997 as compared to the same
        period in 1996.

               The Company recognized net income of $2.6 million for the six
        months ended June 30, 1997 as compared with a net income of $4.7 million
        for the same period in 1996. The decrease in earnings is primarily due
        to the increase in operating expenses for the second quarter of 1997 as
        compared to the same period in 1996.

        LIQUIDITY AND CAPITAL RESOURCES

           At June 30, 1997 and December 31, 1996, cash, cash equivalents and
        marketable securities were in the aggregate $90.8 million and $95.1
        million respectively. While the Company's aggregate level of cash, cash
        equivalents and marketable securities did not change significantly
        during the second quarter of 1997, these levels have fluctuated
        significantly in the past and are expected to do so in the future as a
        result of the factors described below.

           Neurogen's cash requirements to date have been met by the proceeds of
        its financing activities, amounts received pursuant to collaborative
        arrangements and interest earned on invested funds. The Company's
        financing activities include three private placement offerings of its
        common stock prior to its initial public offering, underwritten public
        offerings of the Company's common stock in 1989, 1991 and 1995, and the
        private sale of common stock to Pfizer in connection with entering into
        the Pfizer Agreements and to American Home Products in the American Home
        Products Agreement. Total funding received from these financing
        activities was approximately $105.6 million. The Company's expenditures
        have been primarily to fund research and development and general and
        administrative expenses and to construct and equip its research and
        development facilities.

           In the first quarter of 1992, the Company entered into the 1992
        Pfizer Agreement pursuant to which Pfizer made a $13.8 million equity
        investment in the Company. Under this agreement, the Company received
        $4.6 million in each year from 1992 through 1996. Neurogen could also
        receive milestone payments of up to $12.5 million if certain development
        and regulatory objectives are achieved regarding its products subject to
        the collaboration. In return, Pfizer received the exclusive rights to
        manufacture and market collaboration anxiolytics and cognition enhancers
        that act through the family of receptors which interact with the
        neuro-transmitter gamma-aminobutyric acid, or GABA, and for which it
        will pay Neurogen royalties based upon net sales levels, if any, for
        such products. As of June 30, 1997, Pfizer had provided $25.6 million of
        research funding to the Company pursuant to the 1992 Pfizer Agreement,
        in addition to its $13.8 million equity investment in 1992.

           Neurogen and Pfizer entered into their second collaborative
        agreement, the 1994 Pfizer Agreement, in July 1994, pursuant to which
        Pfizer made an additional $9.9 million equity investment in the Company.
        Under this agreement, the Company received approximately $7.4 million
        during the three-year period which commenced July 1, 1994, to fund
        Neurogen's sleep disorder program. Neurogen could also receive milestone
        payments of up to $3.3 million if certain development and regulatory
        objectives are achieved regarding its products subject to the
        collaboration. As part of this second collaboration, Pfizer received the
        exclusive rights to

                                       7
<PAGE>
 
        manufacture and market GABA-based sleep disorder products for which it
        will pay Neurogen royalties depending upon net sales levels, if any. As
        of June 30, 1997, Pfizer had provided $7.4 of research funding to the
        Company pursuant to the 1994 Pfizer Agreement, in addition to its $9.9
        million equity investment in 1994.

           In December 1996, Neurogen and Pfizer extended the research programs
        under the 1992 Pfizer Agreement and 1994 Pfizer Agreement through 1998.
        Pursuant to the extension agreement, Neurogen expects to receive $5.3
        million in each of 1997 and 1998 for research funding of the Company's
        GABA-based anxiety, cognition enhancement and sleep disorders programs.

           Under both the 1992 Pfizer Agreement and the 1994 Pfizer Agreement,
        in addition to making the equity investments and the research and
        milestone payments noted above, Pfizer is responsible for funding the
        cost of all clinical development and the manufacturing and marketing, if
        any, of drugs developed from the collaborations.

           Neurogen and Pfizer entered into their third collaborative agreement,
        the 1995 Pfizer Agreement, in November 1995, pursuant to which Pfizer
        made an additional $16.5 million equity investment in the Company
        bringing Pfizer's ownership of the Company's common stock up to 21
        percent and paid a $3.5 million license fee. The Company is scheduled to
        receive approximately $7.2 million during the three-year period which
        commenced November 1, 1995, to fund Neurogen's neuropeptide Y (NPY)
        eating disorders program and may receive up to an additional $2.4
        million per year for a fourth and fifth year should Pfizer exercise its
        option to extend the research program under the collaboration. Neurogen
        could also receive milestone payments of up to approximately $28 million
        if certain development and regulatory objectives are achieved regarding
        its products subject to the collaboration. As part of this third
        collaboration, Pfizer received the exclusive worldwide rights to
        manufacture and market NPY-based collaboration compounds, subject to
        certain rights retained by Neurogen. Pursuant to the 1995 Pfizer
        Agreement, Neurogen will fund a minority share of early stage
        development costs and has retained the right to manufacture any
        collaboration products in NAFTA countries and has retained a profit
        sharing option with respect to product sales in NAFTA countries. If
        Neurogen exercises the profit sharing option, it will fund a portion of
        the cost of late stage clinical trials and marketing costs and in return
        receive a specified percentage of any profit generated by sales of
        collaboration products in NAFTA countries. If Neurogen chooses not to
        exercise its profit-sharing option, Pfizer would pay Neurogen royalties
        on drugs marketed in NAFTA countries and would fund a majority of early
        stage and all late stage development and marketing expenses. In either
        case Neurogen would be entitled to royalties on drugs marketed in non-
        NAFTA countries. As of June 30, 1997, Pfizer had provided $4.2 million
        in research funding (including $0.2 million in unearned revenues)
        pursuant to the 1995 Pfizer Agreement.

           In June 1995, Neurogen and Schering-Plough entered into the
        Schering-Plough Agreement to collaborate in the discovery and
        development of drugs for the treatment of schizophrenia and other
        disorders which act through the dopamine family of receptors. Pursuant
        to the Schering-Plough Agreement, the Company received one-time license
        fees of $14 million for rights relating to Neurogen's dopamine program
        and $3 million in 1995 and 1996 for the right to test certain of
        Neurogen's combinatorial chemistry libraries in selected non-CNS assays.
        Neurogen received an aggregate of approximately $7.2 million during the
        two-year period which commenced June 28, 1995, for research and
        development funding of the Company's dopamine program. The Company may
        receive additional research and development funding of up to $3.6
        million per year for three additional one-year periods depending on
        whether and the extent to which Schering-Plough exercises its right to
        extend the research program under the collaboration. In March 1997,
        Schering-Plough elected to extend the research program under the
        Schering-Plough Agreement for an additional one-year period, through
        June 1998. Neurogen could also receive milestone payments of up to
        approximately $32 million if certain development and regulatory
        objectives are achieved regarding its products subject to the
        collaboration. In return, Schering-Plough received the exclusive
        worldwide license to market products subject to the collaboration and
        Neurogen retained the rights to receive royalties based on net sales
        levels, if any, and an option to manufacture products for the United
        States market. As of

                                       8
<PAGE>
 
        June 30, 1997, Schering-Plough had provided $7.2 million in research
        pursuant to the Schering-Plough Agreement. In addition to the payments
        described above, Schering-Plough is responsible for funding the cost of
        all clinical development and marketing, if any, of drugs subject to the
        collaboration.

           In the fourth quarter of 1996, Neurogen entered into an agreement
        with American Home Products Corporation, acting through its Wyeth-Ayerst
        Laboratories division. Under the terms of the agreement, Neurogen
        received $750,000 in license fees for ADCI, a small molecule
        pharmaceutical that Neurogen has been developing for the treatment of
        epilepsy and related disorders, and $750,000 for 37,442 shares of common
        stock. Neurogen may receive up to an additional $11.0 million in the
        form of license fees, equity investment and milestone payments on
        world-wide sales of ADCI.

           The Company plans to use its cash balance for its research and
        development activities, working capital and general corporate purposes.
        Neurogen anticipates that its current cash balance, as supplemented by
        research funding pursuant to the Pfizer Agreements and the
        Schering-Plough Agreement, will be sufficient to fund its current and
        planned operations through 2000. However, Neurogen's funding
        requirements may change and will depend upon numerous factors, including
        but not limited to, the progress of the Company's research and
        development programs, the timing and results of preclinical testing and
        clinical studies, the timing of regulatory approvals, technological
        advances, determinations as to the commercial potential of its proposed
        products, the status of competitive products and the ability of the
        Company to establish and maintain collaborative arrangements with others
        for the purpose of funding certain research and development programs,
        conducting clinical studies, obtaining regulatory approvals and, if such
        approvals are obtained, manufacturing and marketing products. The
        Company anticipates that it may augment its cash balance through
        financing transactions, including the issuance of debt or equity
        securities and further corporate alliances. No arrangements have been
        entered into for any future financing and no assurances can be given
        that adequate levels of additional funding can be obtained on favorable
        terms, if at all.

           As of December 31, 1996, the Company had approximately $11.5 million
        of net operating loss carryforwards available for federal income tax
        purposes which expire from the years 2003 through 2009. The Company had
        approximately $9.4 million of Connecticut state tax net operating loss
        carryforwards as of December 31, 1996 which expire in the years 1997
        through 1999. Because of "change in ownership" provisions of the Tax
        Reform Act of 1986, the Company's utilization of its net operating loss
        carryforwards may be subject to an annual limitation in future periods.

                                       9
<PAGE>
 
                          PART II - OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS

           Not applicable for the second quarter ended June 30, 1997.

ITEM 2. CHANGES IN SECURITIES

           Not applicable for the second quarter ended June 30, 1997.

ITEM 3. DEFAULTS UPON SENIOR SECURITIES

           Not applicable for the second quarter ended June 30, 1997.

ITEM 4. SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         One June 3, 1997 the Company held its annual meeting of stockholders
(I) to elect a board of eleven directors (Proposal 1) and (ii) to approve the
appointment by the Board of Directors of Ernst & Young, LLP as the independent
auditors for the Company for fiscal year ending December 31, 1997 (Proposal 2).

         The stockholders elected the persons named below, the Company's
nominees's for directors, as directors of the Company, casting votes in favor of
such nominees or withholding votes as indicated:

                                   Votes in Favor           Votes Withheld

Barry M. Bloom, Ph.D.               11,243,038                   20,625
Robert N. Butler                    11,243,638                   20,025
Frank C. Carlucci                   11,243,638                   20,025
Jeffrey J. Collinson                11,243,638                   20,025
Robert M. Gardiner                  11,243,138                   20,525
Richard D. Harrison                 11,243,638                   20,025
Mark Novitch, M.D.                  11,243,638                   20,025
Harry H. Penner, Jr.                11,243,638                   20,025
Robert H. Roth, Ph.D.               11,243,638                   20,025
John Simon                          11,243,638                   20,025
John F. Tallman, Ph.D.              11,243,638                   20,025


         The stockholders approved Proposal 2, voting as follows:

Affirmative Votes     Negative Votes        Votes Abstained
- -----------------     --------------        ---------------
11,244,819            8,825                        10,019


ITEM 5. OTHER INFORMATION

           Not applicable for the second quarter ended June 30, 1997.

ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K

         (a) See Exhibit Index on page 11.

         (b) None


                                       10
<PAGE>
 
SAFE HARBOR STATEMENT

Statements which are not historical facts, including statements about the
Company's confidence and strategies, the status of various product development
programs, the sufficiency of cash to fund planned operations and the Company's
expectations concerning its development compounds, drug discovery technologies
and opportunities in the pharmaceutical marketplace are "forward looking
statements" within the meaning of the Private Securities Litigations Reform Act
of 1995 that involve risks and uncertainties and are not guarantees of future
performance. These risks include, but are not limited to, difficulties or delays
in development, testing, regulatory approval, production and marketing of any of
the Company's drug candidates, the failure to attract or retain scientific
management personnel, any unexpected adverse side effects or inadequate
therapeutic efficacy of the Company's drug candidates which could slow or
prevent product development efforts, competition within the Company's
anticipated product markets, the Company's dependence on corporate partners with
respect to research and development funding, regulatory filings and
manufacturing and marketing expertise, the uncertainty of product development in
the pharmaceutical industry, inability to obtain sufficient funds through future
collaborative arrangements, equity or debt financings or other sources to
continue the operation of the Company's business, risk that patents and
confidentiality agreements will not adequately protect the Company's
intellectual property or trade secrets, dependence upon third parties for the
manufacture of potential products, inexperience in manufacturing and lack of
internal manufacturing capabilities, dependence on third parties to market
potential products, lack of sales and marketing capabilities, potential
unavailability or inadequacy of medical insurance or other third-party
reimbursement for the cost of purchases of the Company's products, and other
risks detailed in the Company's Securities and Exchange Commission filings,
including its Annual Report on Form 10-K for the year ended December 31, 1996,
each of which could adversely affect the Company's business and the accuracy of
the forward-looking statements contained herein.

                                       11
<PAGE>
 
                                   Signature

        Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

                                             NEUROGEN CORPORATION

                                             By:/s/   STEPHEN R. DAVIS
                                               ---------------------------
                                             Stephen R. Davis
                                             Vice President-Finance and
                                             Chief Financial Officer

Date:  August 13, 1997

                                       12
<PAGE>
 
                                 Exhibit Index
                                 -------------

        Exhibit
        Number

        10.1     -        Neurogen Corporation Stock Option Plan, as amended
                          (incorporated by reference to Exhibit 10.1 to the
                          Company's Form 10-K for the fiscal year ended December
                          31, 1991).

        10.2     -        Form of Stock Option Agreement currently used in
                          connection with the grant of options under Neurogen
                          Corporation Stock Option Plan (incorporated by
                          reference to Exhibit 10.2 to the Company's Form 10-K
                          for the fiscal year ended December 31, 1992).

        10.3     -        Neurogen Corporation 1993 Omnibus Incentive Plan, as
                          amended (incorporated by reference to Exhibit 10.3 to
                          the Company's Form 10-K for the fiscal year ended
                          December 31, 1993).

        10.4     -        Form of Stock Option Agreement currently used in
                          connection with the grant of options under Neurogen
                          Corporation 1993 Omnibus Incentive Plan (incorporated
                          by reference to Exhibit 10.4 to the Company's Form 10-
                          K for the fiscal year ended December 31, 1993).

        10.5     -        Neurogen Corporation 1993 Non-Employee Directors Stock
                          Option Program (incorporated by reference to Exhibit
                          10.5 to the Company's Form 10-K for the fiscal year
                          ended December 31, 1993).

        10.6     -        Form of Stock Option Agreement currently used in
                          connection with the grant of options under Neurogen
                          Corporation 1993 Non-Employee Directors Stock Option
                          Program (incorporated by reference to Exhibit 10.6 to
                          the Company's Form 10-K for the fiscal year ended
                          December 31, 1993).

        10.7     -        Employment Contract between the Company and Harry H.
                          Penner, Jr., dated as of October 12, 1993
                          (incorporated by reference to Exhibit 10.7 to the
                          Company's Form 10-K for the fiscal year ended December
                          31, 1993).

        10.8     -        Employment Contract between the Company and John F.
                          Tallman, dated as of December 1, 1993 (incorporated by
                          reference to Exhibit 10.25 to the Company's Form 10-Q
                          for the quarterly period ended September 30, 1994).

        10.9     -        Open-End Mortgage Deed and Security Agreement between
                          the Company and Orion Machinery & Engineering Corp.,
                          dated March 16, 1989 (incorporated by reference to
                          Exhibit 10.15 to Registration Statement No. 33-29709
                          on Form S-1).

                                       13
<PAGE>
 
        10.10    -        Form of Proprietary Information and Inventions
                          Agreement (incorporated by reference to Exhibit 10.31
                          to Registration Statement No. 33-29709 on Form S-1).

        10.11    -        Warrant to Purchase 47,058 Shares of Common Stock to
                          MMC/GATX Partnership No. I, dated February 20, 1991
                          (incorporated by reference to Exhibit 10.34 to the
                          Company's Form 10-K for the fiscal year ended December
                          31, 1990).

        10.12    -        Collaborative Research Agreement and License and
                          Royalty Agreement between the Company and Pfizer Inc,
                          dated as of January 1, 1992 (confidential treatment
                          requested) (incorporated by reference to Exhibit 10.35
                          to the Company's Form 10-K for the fiscal year ended
                          December 31, 1991).

        10.13    -        License Agreement between the Company and the National
                          Technical Information Service, dated as of January 1,
                          1992 (incorporated by reference to Exhibit 10.36 to
                          the Company's Form 10-K for the fiscal year ended
                          December 31, 1991).

        10.14    -        Cooperative Research and Development Agreement between
                          the Company and the National Institutes of Health,
                          dated as of January 21, 1993 (incorporated by
                          reference to Exhibit 10.37 to the Company's Form 10-K
                          for the fiscal year ended December 31, 1991).

        10.15    -        Letter Agreement between the Company and Barry M.
                          Bloom, dated January 12, 1994 (incorporated by
                          reference to Exhibit 10.25 to the Company's Form 10-K
                          for the fiscal year ended December 31, 1993).

        10.16    -        Letter Agreement between the Company and Robert H.
                          Roth, dated April 14, 1994 (incorporated by reference
                          to Exhibit 10.26 to the Company's Form 10-K for the
                          fiscal year ended December 31, 1994).

        10.17    -        Collaborative Research Agreement and License and
                          Royalty Agreement between the Company and Pfizer Inc,
                          dated as of July 1, 1994 (confidential treatment
                          requested) (incorporated by reference of Exhibit 10.1
                          to the Company's Form 10-Q for the quarterly period
                          ended June 30, 1994).

        10.18    -        Stock Purchase Agreement between the Company and
                          Pfizer dated as of July 1, 1994 (incorporated by
                          reference to Exhibit 10.2 to the Company's Form 10-Q
                          for the quarterly period ended June 30, 1994).

                                       14
<PAGE>
 
        10.19    -        Registration Rights and Standstill Agreement among the
                          Company and the Persons and Entities listed on
                          Schedule I thereto, dated as of July 11, 1994
                          (incorporated by reference to Exhibit 10.29 to the
                          Company's Form 10-Q for the quarterly period ended
                          September 30, 1994).

        10.20    -        Collaboration and License Agreement and Screening
                          Agreement between the Company and Schering-Plough
                          Corporation (confidential treatment requested)
                          (incorporated by reference to Exhibit 10.1 to the
                          Company's Form 8-K dated July 28, 1995).

        10.21    -        Lease Agreement between the Company and Commercial
                          Building Associates dated as of August 30, 1995
                          (incorporated by reference to Exhibit 10.27 to the
                          Company's Form 10-Q for the quarterly period ended
                          September 30, 1995).

        10.22    -        Collaborative Research Agreement between the Company
                          and Pfizer dated as of November 1, 1995 (confidential
                          treatment requested) (incorporated by reference to
                          Exhibit 10.1 of the Company's Form 8-K dated November
                          1, 1995).

        10.23             Development and Commercialization Agreement between
                          the Company and Pfizer dated as of November 1, 1995
                          (confidential treatment requested) (incorporated by
                          reference to Exhibit 10.2 of the Company's Form 8-K
                          dated November 1, 1995).

        10.24    -        Stock Purchase Agreement between the Company and
                          Pfizer dated as of November 1, 1995 (incorporated by
                          reference to Exhibit 10.3 of the Company's Form 8-K
                          dated November 1, 1995).

        10. 25   -        Licensing Agreement dated as of November 25, 1996
                          between American Home Products Corporation, acting
                          through its Wyeth-Ayerst Laboratories Division, and
                          Neurogen Corporation CONFIDENTIAL TREATMENT REQUESTED)
                          (incorporated by reference to Exhibit 10.1 of the
                          Company's Form 8-K dated March 31, 1997).

        10. 26   -        Stock Purchase Agreement dated as of November 25, 1996
                          between American Home Products Corporation, acting
                          through its Wyeth-Ayerst Laboratories Division, and
                          Neurogen Corporation (CONFIDENTIAL TREATMENT
                          REQUESTED) (incorporated by reference to Exhibit 10.1
                          of the Company's Form 8-K dated March 31, 1997).

        11.1     -        Computation of Earnings per Common Share.

        27.1     -        Financial Data Schedule

                                       15

<PAGE>
 
                                                                    EXHIBIT 11.1

                             NEUROGEN CORPORATION
               COMPUTATION OF NET INCOME (LOSS) PER COMMON SHARE
       (in thousands, except Net Income (Loss) per Common Share amounts)

<TABLE> 
<CAPTION> 
                                                      THREE MONTHS       THREE MONTHS      SIX MONTHS           SIX MONTHS
                                                         ENDED              ENDED              ENDED               ENDED
                                                      JUNE 30, 1997      JUNE 30, 1996    JUNE 30, 1997       JUNE 30, 1996
                                                      (UNAUDITED)        (UNAUDITED)        (UNAUDITED)         (UNAUDITED)
                                                      -----------        -----------        -----------          ----------
              Primary:
<S>                                                 <C>              <C>                <C>                    <C> 
              Weighted average shares of
                common stock outstanding                   14,339             14,141             14,313                14,081

              Dilutive effect of :
                  Warrants                                (1)                     43                 36                    43
                  Stock options                           (1)                  1,349                996                 1,412
                                                      ------------       ------------       ------------       ---------------

              Common and common
                equivalent shares                          14,339             15,533             15,345                15,536
                                                      ============       ============       ============       ===============

              Net income (loss)                       $       (255)    $        1,118     $        2,595     $           4,728
                                                      ============       ============       ============       ===============

              Earnings (loss) per common and
                common equivalent shares              $      (0.02)    $         0.07     $         0.17     $            0.30
                                                      ============       ============       ============       ===============

              Fully Diluted:
              Weighted average shares of
                common stock outstanding                   14,339             14,141             14,313                14,081

              Dilutive effect of :
                  Warrants                                (1)                     43                 36                    43
                  Stock options                           (1)                  1,349              1,098                 1,412
                                                      ------------       ------------       ------------       ---------------

              Common and common
                equivalent shares                          14,339             15,533             15,447                15,536
                                                      ============       ============       ============       ===============

              Net income (loss)                       $       (255)    $        1,118     $        2,595     $           4,728
                                                      ============       ============       ============       ===============

              Earnings (loss) per common and
                common equivalent shares              $      (0.02)    $         0.07     $         0.17     $            0.30
                                                      ============       ============       ============       ===============
</TABLE> 

              (1) The Common Stock Equivalents have not been included as their
inclusion would be antidilutive.

<TABLE> <S> <C>

<PAGE>
 
<ARTICLE> 5
<MULTIPLIER> 1,000
       
<S>                             <C>
<PERIOD-TYPE>                   6-MOS
<FISCAL-YEAR-END>                          DEC-31-1997
<PERIOD-START>                             JAN-01-1997
<PERIOD-END>                               JUN-30-1997
<CASH>                                           53681
<SECURITIES>                                     37091
<RECEIVABLES>                                        0
<ALLOWANCES>                                         0
<INVENTORY>                                          0
<CURRENT-ASSETS>                                 92570
<PP&E>                                           24846
<DEPRECIATION>                                    3916
<TOTAL-ASSETS>                                  113873
<CURRENT-LIABILITIES>                             4150
<BONDS>                                              0
                                0
                                          0
<COMMON>                                           359
<OTHER-SE>                                        (27)
<TOTAL-LIABILITY-AND-EQUITY>                    113873
<SALES>                                              0
<TOTAL-REVENUES>                                 10928
<CGS>                                                0
<TOTAL-COSTS>                                    10794
<OTHER-EXPENSES>                                (2496)
<LOSS-PROVISION>                                     0
<INTEREST-EXPENSE>                                  21
<INCOME-PRETAX>                                   2630
<INCOME-TAX>                                        35
<INCOME-CONTINUING>                               2595
<DISCONTINUED>                                       0
<EXTRAORDINARY>                                      0
<CHANGES>                                            0
<NET-INCOME>                                      2595
<EPS-PRIMARY>                                      .17
<EPS-DILUTED>                                      .17
        

</TABLE>


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