<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ SUZANNE WOOLSEY
-------------------------------------
Suzanne Woolsey
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ JOHN F. TALLMAN, PH.D.
-------------------------------------
John F. Tallman, Ph.D.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ JOHN SIMON
-------------------------------------
John Simon
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ ROBERT H. ROTH, PH.D.
-------------------------------------
Robert H. Roth, Ph.D.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ HARRY H. PENNER, JR.
-------------------------------------
Harry H. Penner, Jr.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ MARK NOVITCH, M.D.
-------------------------------------
Mark Novitch, M.D.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ JULIAN C. BAKER
-------------------------------------
Julian C. Baker
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ FELIX J. BAKER
-------------------------------------
Felix J. Baker
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ BARRY M. BLOOM, PH.D.
-------------------------------------
Barry M. Bloom, Ph.D.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ ROBERT N. BUTLER, M.D.
-------------------------------------
Robert N. Butler, M.D.
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ FRANK C. CARLUCCI
-------------------------------------
Frank C. Carlucci
<PAGE>
POWER OF ATTORNEY
KNOW ALL YE PERSONS BY THESE PRESENTS, that the undersigned does hereby
make, constitute and appoint Harry H. Penner, Jr. and Stephen R. Davis, each his
attorney-in-fact and agent with full power of substitution and resubstitution
for him and in his name, place and stead, in any and all capacities, to execute
for him and on his behalf a registration statement pursuant to the Securities
Act of 1933, as amended, on Form S-3 relating to the 1,638,000 shares of common
stock, par value $.025 per share of Neurogen Corporation issued in connection
with the Company's recently completed Private Investment in Public Equity Common
Stock Offering, and any and all amendments (including post-effective amendments)
to the foregoing registration statement which amendments may make such changes
in the registration statement as such attorney-in-fact deems appropriate, and
any other documents and instruments incidental thereto, and any registration
statement of the Neurogen Corporation relating to the common stock filed after
the date hereof pursuant to Rule 462(b) under the Securities Act, and to file
the same, with all exhibits thereto and all documents in connection therewith,
with the Securities and Exchange Commission, the Nasdaq Stock Market, and/or the
National Association of Securities Dealers, Inc., granting unto said attorney-
in-fact and agent, full power and authority to do and perform each and every act
and thing requisite and necessary to be done in and about the premises, as fully
to all intents and purposes as the undersigned might or could do in person,
hereby ratifying and confirming all that said attorney-in-fact and agent, or his
substitute or substitutes, may lawfully do or cause to be done by virtue hereof.
IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney
this 11th day of July, 2000.
/s/ JEFFREY J. COLLINSON
-------------------------------------
Jeffrey J. Collinson
