CORTEX PHARMACEUTICALS INC/DE/
SC 13D/A, 1997-01-06
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 3)*

                          CORTEX PHARMACEUTICALS, INC.
                    ---------------------------------------
                                (Name of Issuer)

                         Common Stock, $0.001 Par Value
                     --------------------------------------
                         (Title of Class of Securities)

                                    22054300
                              --------------------
                                 (CUSIP Number)

                              Stephen M. Vine, Esq.
                    Akin, Gump, Strauss, Hauer & Feld, L.L.P.
                                 399 Park Avenue
                            New York, New York 10022
                                 (212) 872-1000
                  -------------------------------------------
                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                 January 1, 1997
                           --------------------------
                      (Date of Event which Requires Filing
                               of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 1d-1(b)(3) or (4), check the following box [_].

Check the following box if a fee is being paid with the statement  [_].** (A fee
is not required only if the reporting  person:  (1) has a previous  statement on
file  reporting  beneficial  ownership of more than five percent of the class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7)

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.



                         Continued on following page(s)
                               Page 1 of 14 Pages
                             Exhibit Index: Page 11



- --------

*         Initial  filing  with  respect  to Soros Fund  Management  LLC and Mr.
          Stanley F. Druckenmiller.
**        A filing fee is not being  paid with this  statement  pursuant  to SEC
          Release No.  33-7331  whereby the filing fee has been  eliminated  for
          Schedule 13D.


<PAGE>


                                                              Page 2 of 14 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               Soros Fund Management LLC

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [X]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               Delaware

                      7      Sole Voting Power
 Number of                          875,000
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          0
    Each
  Reporting           9      Sole Dispositive Power
   Person                           875,000
    With
                      10     Shared Dispositive Power
                                    0

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    875,000

12      Check Box If the Aggregate  Amount in Row (11) Excludes  Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             11.27%

14      Type of Reporting Person*

               OO; IA

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                              Page 3 of 14 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               George Soros  (in the capacity described herein)

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [X]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               United States

                      7      Sole Voting Power
 Number of                          0
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          875,000
    Each
  Reporting           9      Sole Dispositive Power
   Person                           0
    With
                      10     Shared Dispositive Power
                                    875,000

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    875,000

12      Check Box If the Aggregate Amount in Row (11) Excludes Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             11.27%

14      Type of Reporting Person*

               IA

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                              Page 4 of 14 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               Stanley F. Druckenmiller (in the capacity described herein)

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [X]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               United States

                      7      Sole Voting Power
 Number of                          0
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          875,000
    Each
  Reporting           9      Sole Dispositive Power
   Person                           0
    With
                      10     Shared Dispositive Power
                                    875,000

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    875,000

12      Check Box If the Aggregate Amount in Row (11) Excludes Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             11.27%

14      Type of Reporting Person*

               IA
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                              Page 5 of 14 Pages

               This  Amendment No. 3 to Schedule 13D relates to shares of Common
Stock,  $0.001 par value per share (the  "Shares"),  of Cortex  Pharmaceuticals,
Inc. (the  "Issuer").  This  Amendment No. 3  supplementally  amends the initial
statement on Schedule 13D dated  November  12, 1993 and all  amendments  thereto
(collectively,  the "Initial  Statement")  filed by one of the Reporting Persons
(as  defined  herein).  This  Amendment  No. 3 is being  filed by the  Reporting
Persons to report the transfer of the investment advisory contract between Soros
Fund Management  ("SFM") and Quantum Fund N.V., a Netherlands  Antilles  company
("Quantum Fund"),  whose principal operating  subsidiary is Quantum Partners LDC
("Quantum  Partners"),  a Cayman  Islands  exempted  limited  duration  company,
pursuant  to  which  SFM  was  granted  investment   discretion  over  portfolio
investments, including the Shares, held for the account of Quantum Partners. The
investment  advisory  contract  has been  transferred  from  SFM to  Soros  Fund
Management LLC ("SFM LLC"), a newly formed Delaware limited  liability  company.
Capitalized  terms used herein but not defined  herein  shall have the  meanings
ascribed  to  them  in  the  Initial   Statement.   The  Initial   Statement  is
supplementally amended as follows.

Item 2.        Identity and Background.

               This  statement is being filed on behalf of SFM LLC,  Mr.  George
Soros ("Mr. Soros") and Mr. Stanley F. Druckenmiller  ("Mr.  Druckenmiller," and
together with SFM LLC and Mr. Soros,  the "Reporting  Persons").  This statement
relates to Shares held for the account of Quantum Partners.

               Effective as of January 1, 1997,  SFM, a sole  proprietorship  of
which Mr. Soros is the sole  proprietor,  transferred  its  investment  advisory
contract with Quantum Fund to SFM LLC as part of a restructuring of the business
of SFM,  which will now be conducted  through SFM LLC. SFM LLC has its principal
office at 888  Seventh  Avenue,  33rd  Floor,  New  York,  New York  10106.  Its
principal  business  is  to  serve,  pursuant  to  contract,  as  the  principal
investment manager to several foreign investment  companies (the "SFM Clients"),
including  Quantum Fund and Quantum  Partners.  Each of Quantum Fund and Quantum
Partners has its  principal  office at Kaya  Flamboyan 9,  Willemstad,  Curacao,
Netherlands  Antilles.  SFM LLC's contracts with SFM Clients  generally  provide
that SFM LLC is  responsible  for  designing and  implementing  the SFM Clients'
overall  investment   strategy;   for  conducting  direct  portfolio  management
strategies  to the extent  that SFM LLC  determines  that it is  appropriate  to
utilize its own portfolio management capabilities; for selecting, evaluating and
monitoring other investment advisors who manage separate portfolios on behalf of
SFM Clients;  and for allocating and  reallocating the SFM Clients' assets among
the outside managers and itself.

               The business of SFM LLC is managed through a Management Committee
(the "Management  Committee")  comprised of Mr. Soros, Mr. Druckenmiller and Mr.
Gary Gladstein. Mr. Soros, as Chairman of SFM LLC, has the ability to direct the
investment  decisions  of SFM LLC and as such may be deemed  to have  investment
discretion  over the  securities  held for the accounts of the SFM Clients.  Mr.
Druckenmiller,  as Lead Portfolio  Manager of SFM LLC, has the ability to direct
the investment decisions of SFM LLC and as such may be deemed to have investment
discretion  over the  securities  held for the accounts of the SFM Clients.  Set
forth in Annex A hereto and incorporated by reference in response to this Item 2
and  elsewhere  in this  Schedule  13D as  applicable  is a list of the Managing
Directors of SFM LLC.

               The principal  occupation of Mr. Soros, a United States  citizen,
is his  direction  of the  activities  of SFM LLC,  which is carried  out in his
capacity as Chairman of SFM LLC at SFM LLC's principal office.

               The principal  occupation of Mr.  Druckenmiller,  a United States
citizen,  is  his  position  as  Lead  Portfolio  Manager  and a  Member  of the
Management  Committee  of SFM LLC,  which is carried out at SFM LLC's  principal
office.



<PAGE>


                                                              Page 6 of 14 Pages

               Pursuant to  regulations  promulgated  under Section 13(d) of the
Act,  SFM  LLC,  Mr.  Soros,  in his  capacity  as  Chairman  of SFM LLC and Mr.
Druckenmiller, in his capacity as Lead Portfolio Manager of SFM LLC, each may be
deemed a beneficial  owner of  securities,  including  the Shares,  held for the
account of Quantum Partners as a result of the contractual  authority of SFM LLC
to exercise voting and dispositive power with respect to such securities.

               During  the  past  five  years,  none of the  Reporting  Persons,
Quantum Partners and, to the best of the Reporting Persons' knowledge, any other
person  identified  in  response  to this  Item 2 has  been (a)  convicted  in a
criminal proceeding, or (b) a party to any civil proceeding as a result of which
he has been  subject  to a  judgment,  decree or final  order  enjoining  future
violations  of, or prohibiting  or mandating  activities  subject to, federal or
state securities laws, or finding any violation with respect to such laws.

Item 3.        Source and Amount of Funds or Other Consideration.

               The  securities  held for the  accounts of the SFM Clients may be
held through margin accounts maintained with brokers, which extend margin credit
as and when required to open or carry positions in its margin accounts,  subject
to applicable federal margin  regulations,  stock exchange rules and such firm's
credit  policies.  The  positions  which  may be  held in the  margin  accounts,
including the Shares,  are pledged as  collateral  security for the repayment of
debit balances in the respective accounts.

Item 4.        Purpose of Transaction.

               All of the Shares  reported herein as having been acquired for or
disposed of from the account of Quantum  Partners  were  acquired or disposed of
for investment purposes. Neither Quantum Partners, the Reporting Persons nor, to
the best of their knowledge, any of the other individuals identified in response
to Item 2, has any plans or  proposals  that relate to or would result in any of
the  transactions  described  in  subparagraphs  (a)  through  (j) of  Item 4 of
Schedule 13D. The Reporting Persons reserve the right to acquire, or cause to be
acquired,  additional  securities  of the Issuer,  to dispose of, or cause to be
disposed,  such securities at any time or to formulate other purposes,  plans or
proposals  regarding the Issuer or any of its  securities,  to the extent deemed
advisable in light of general  investment and trading  policies of the Reporting
Persons and\or SFM Clients, market conditions or other factors.

Item 5.        Interest in Securities of the Issuer.

               (a) The aggregate number of Shares of which each of the Reporting
Persons  may be deemed the  beneficial  owner is 875,000  Shares  (approximately
11.27% of the total number of Shares outstanding).

               (b)  (i)  Pursuant to the terms of the contract  between  Quantum
Fund and SFM LLC,  SFM LLC may be deemed to have sole power to direct the voting
and disposition of the 875,000 Shares held for the account of Quantum Partners.

                    (ii) Pursuant to the terms of the contract  between  Quantum
Fund and SFM LLC and as a result  of the  positions  held by Mr.  Soros  and Mr.
Druckenmiller  with SFM LLC,  each of Mr.  Soros  and Mr.  Druckenmiller  may be
deemed to have shared power to direct the voting and  disposition of the 875,000
Shares held for the account of Quantum Partners.



<PAGE>


                                                              Page 7 of 14 Pages

               (c) Except as disclosed in Item 2 hereof,  which is  incorporated
by reference in this Item 5 and the transactions listed on Annex B hereto, there
have been no transactions effected with respect to the Shares since November 18,
1996,  the date of the last filing on Schedule  13D  relating to the Shares,  by
Quantum  Partners or by any of the Reporting  Persons.  All of the  transactions
listed  on  Annex B were  executed  in  routine  brokerage  transactions  in the
over-the-counter market.

               (d) The  shareholders  of  Quantum  Partners  have  the  right to
participate  in the receipt of  dividends  from,  or proceeds  from the sale of,
securities,  including the Shares,  held for the account of Quantum  Partners in
accordance with their ownership interests in Quantum Partners.

               (e) Not applicable.

Item 6.        Contracts,  Arrangements,  Understandings in Relationship with
               Respect to Securities of the Issuer.

               From  time  to  time,  each  of the  Reporting  Persons,  Quantum
Partners  and/or  other SFM Clients may lend  portfolio  securities  to brokers,
banks or other  financial  institutions.  These  loans  typically  obligate  the
borrower to return the securities,  or an equal amount of securities of the same
class,  to the lender and  typically  provide  that the  borrower is entitled to
exercise voting rights and to retain dividends during the term of the loan. From
time to time to the extent  permitted by applicable  laws, each of the Reporting
Persons,  Quantum  Partners  and/or  other SFM  Clients  may borrow  securities,
including the Shares, for the purpose of effecting,  and may effect,  short sale
transactions,  and may purchase  securities for the purpose of closing out short
positions in such securities.

               Except as disclosed  above and in the Purchase  Agreement,  which
was filed as Exhibit B to the Initial Statement and is incorporated by reference
in response to this Item 6, the Reporting  Persons,  Quantum  Partners and other
SFM  Clients  do  not  have  any  contracts,  arrangements,   understandings  or
relationships with respect to any securities of the Issuer.

Item 7.        Material to be Filed as Exhibits.

               A. Power of Attorney  dated as of January 1, 1997  granted by Mr.
Soros in favor of Mr. Sean C. Warren and Mr. Michael C. Neus.

               B. Purchase  Agreement dated November 5, 1993, between the Issuer
and  Quantum  Partners  (filed  as  Exhibit  B  to  the  Initial  statement  and
incorporated herein by reference).

               C. Power of Attorney  dated as of January 1, 1997  granted by Mr.
Druckenmiller in favor of Mr. Sean C. Warren and Mr. Michael C. Neus.

               D. Joint Filing  Agreement dated January 1, 1997 by and among SFM
LLC, Mr. Soros and Mr. Druckenmiller.



<PAGE>


                                                              Page 8 of 14 Pages

                                   SIGNATURES

               After  reasonable  inquiry  and to the best of my  knowledge  and
belief,  the  undersigned  certifies  that  the  information  set  forth in this
statement is true, complete and correct.

Date:  January 1, 1997                      SOROS FUND MANAGEMENT LLC


                                            By:    /S/ SEAN C. WARREN
                                                  -----------------------------
                                                   Sean C. Warren
                                                   Managing Director


                                            GEORGE SOROS


                                            By:    /S/ SEAN C. WARREN
                                                  -----------------------------
                                                   Sean C. Warren
                                                   Attorney-in-Fact


                                            STANLEY F. DRUCKENMILLER


                                            By:    /S/ SEAN C. WARREN
                                                  -----------------------------
                                                   Sean C. Warren
                                                   Attorney-in-Fact





<PAGE>


                                                              Page 9 of 14 Pages

                                     ANNEX A


               The following is a list of all of the persons (other than Stanley
Druckenmiller) who serve as Managing Directors of SFM LLC:



                               Scott K. H. Bessent
                                 Walter Burlock
                               Jeffrey L. Feinberg
                                  Arminio Fraga
                                 Gary Gladstein
                                Robert K. Jermain
                                 David N. Kowitz
                               Alexander C. McAree
                                  Paul McNulty
                              Gabriel S. Nechamkin
                                   Steven Okin
                                  Dale Precoda
                               Lief D. Rosenblatt
                                 Mark D. Sonnino
                             Filiberto H. Verticelli
                                 Sean C. Warren

Each of the  above-listed  persons is a United States  citizen  whose  principal
occupation  is serving as Managing  Director of SFM LLC, and each has a business
address c/o Soros Fund Management LLC, 888 Seventh Avenue, 33rd Floor, New York,
New York 10106.




<PAGE>


                                                             Page 10 of 14 Pages
<TABLE>
<CAPTION>

                                               ANNEX B

                             RECENT TRANSACTIONS IN THE COMMON STOCK OF
                                    CORTEX PHARMACEUTICALS, INC.


                                Date of          Nature of
For the Account of            Transaction       Transaction      Number of Shares     Price Per Share
- ------------------          -------------       -----------      ----------------     ---------------
<S>                        <C>                 <C>              <C>                  <C>

Quantum Partners LDC\1\        11/27/96            Sale               10,000               $5.625




</TABLE>






















- ----------------------
\1\    Transactions effected at the direction of SFM.



<PAGE>


                                                             Page 11 of 14 Pages

                                  EXHIBIT INDEX


                                                                        Page No.
                                                                        --------


A.        Power of Attorney  dated as of January 1, 1997  granted by
          Mr.  George Soros  in  favor  of  Mr.   Sean  C.   Warren
          and  Mr.   Michael  C. Neus...................................   12

C.        Power of Attorney dated as of January 1, 1997 granted by Mr.
          Stanley F. Druckenmiller in favor of Mr. Sean C. Warren and
          Mr. Michael C. Neus...........................................   13

D.        Joint Filing Agreement dated January 1, 1997 by and among 
          Soros Fund Management LLC, Mr. George Soros and Mr. Stanley
          F. Druckenmiller..............................................   14








                                                             Page 12 of 14 Pages

                                    EXHIBIT A

                                POWER OF ATTORNEY


KNOW ALL MEN BY THESE PRESENTS,  that I, GEORGE SOROS,  hereby make,  constitute
and appoint each of SEAN C. WARREN and MICHAEL C. NEUS, acting individually,  as
my agent and attorney-in-fact for the purpose of executing in my name, (a) in my
personal  capacity or (b) in my capacity as Chairman  of,  member of or in other
capacities  with  Soros  Fund  Management  LLC,  all  documents,   certificates,
instruments,  statements,  filings and agreements ("documents") to be filed with
or  delivered  to any foreign or domestic  governmental  or  regulatory  body or
required or  requested  by any other  person or entity  pursuant to any legal or
regulatory  requirement  relating to the acquisition,  ownership,  management or
disposition of securities or other investments, and any other documents relating
or ancillary  thereto,  including but not limited to, all documents  relating to
filings with the United States  Securities and Exchange  Commission  (the "SEC")
pursuant to the Securities  Act of 1933 or the  Securities  Exchange Act of 1934
(the "Act") and the rules and regulations promulgated thereunder, including: (1)
all documents relating to the beneficial  ownership of securities required to be
filed  with  the SEC  pursuant  to  Section  13(d) or  Section  16(a) of the Act
including, without limitation: (a) any acquisition statements on Schedule 13D or
Schedule  13G and  any  amendments  thereto,  (b) any  joint  filing  agreements
pursuant to Rule  13d-1(f) and (c) any initial  statements  of, or statements of
changes in,  beneficial  ownership of securities on Form 3, Form 4 or Form 5 and
(2) any  information  statements  on Form 13F  required to be filed with the SEC
pursuant to Section 13(f) of the Act.

All past acts of the attorney-in-fact in furtherance of the foregoing are hereby
ratified and confirmed.

This power of attorney shall be valid from the date hereof until revoked by me.

IN  WITNESS  WHEREOF,  I have  executed  this  instrument  as of the  1st day of
January, 1997.




                                /s/ George Soros
                                ----------------------------------
                                GEORGE SOROS





                                                             Page 13 of 14 Pages

                                    EXHIBIT C
                                POWER OF ATTORNEY


KNOW ALL MEN BY THESE PRESENTS,  that I, STANLEY F. DRUCKENMILLER,  hereby make,
constitute  and  appoint  each of SEAN C.  WARREN and  MICHAEL  C. NEUS,  acting
individually,  as my agent and  attorney-in-fact for the purpose of executing in
my name,  (a) in my personal  capacity  or (b) in my capacity as Lead  Portfolio
Manager of, member of or in other capacities with Soros Fund Management LLC, all
documents,  certificates,   instruments,   statements,  filings  and  agreements
("documents")  to be  filed  with  or  delivered  to  any  foreign  or  domestic
governmental  or regulatory body or required or requested by any other person or
entity  pursuant  to  any  legal  or  regulatory  requirement  relating  to  the
acquisition,  ownership,  management  or  disposition  of  securities  or  other
investments,  and any other documents relating or ancillary  thereto,  including
but not limited to, all  documents  relating to filings  with the United  States
Securities and Exchange Commission (the "SEC") pursuant to the Securities Act of
1933 or the  Securities  Exchange  Act of 1934  (the  "Act")  and the  rules and
regulations promulgated thereunder, including: (1) all documents relating to the
beneficial ownership of securities required to be filed with the SEC pursuant to
Section 13(d) or Section 16(a) of the Act including, without limitation: (a) any
acquisition  statements  on  Schedule  13D or  Schedule  13G and any  amendments
thereto,  (b) any joint filing agreements  pursuant to Rule 13d-1(f) and (c) any
initial  statements  of, or  statements of changes in,  beneficial  ownership of
securities  on Form 3, Form 4 or Form 5 and (2) any  information  statements  on
Form 13F required to be filed with the SEC pursuant to Section 13(f) of the Act.

All past acts of the attorney-in-fact in furtherance of the foregoing are hereby
ratified and confirmed.

This power of attorney shall be valid from the date hereof until revoked by me.

IN  WITNESS  WHEREOF,  I have  executed  this  instrument  as of the  1st day of
January, 1997.




                                            /s/ Stanley F. Druckenmiller
                                            ------------------------------------
                                            STANLEY F. DRUCKENMILLER




                                                             Page 14 of 14 Pages



                                    EXHIBIT D

                             JOINT FILING AGREEMENT

               The  undersigned  hereby agree that the statement on Schedule 13D
with respect to the Common Stock of Cortex  Pharmaceuticals,  Inc. dated January
1, 1997 is, and any amendments  thereto signed by each of the undersigned  shall
be,  filed  on  behalf  of each of us  pursuant  to and in  accordance  with the
provisions of Rule 13d-1(f) under the Securities Exchange Act of 1934.

Date:  January 1, 1997                      SOROS FUND MANAGEMENT LLC


                                            By:    /S/ SEAN C. WARREN
                                                   -----------------------------
                                                   Sean C. Warren
                                                   Managing Director


                                                   GEORGE SOROS


                                            By:    /S/ SEAN C. WARREN
                                                   -----------------------------
                                                   Sean C. Warren
                                                   Attorney-in-Fact


                                            STANLEY F. DRUCKENMILLER


                                            By:    /S/ SEAN C. WARREN
                                                   -----------------------------
                                                   Sean C. Warren
                                                   Attorney-in-Fact


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