CORTEX PHARMACEUTICALS INC/DE/
SC 13D/A, 1997-02-18
PHARMACEUTICAL PREPARATIONS
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13D

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 4)*

                          CORTEX PHARMACEUTICALS, INC.
                ------------------------------------------------
                                (Name of Issuer)

                         Common Stock, $0.001 Par Value
                   ------------------------------------------
                         (Title of Class of Securities)

                                    22054300
                            ------------------------
                                 (CUSIP Number)

                              Stephen M. Vine, Esq.
                    Akin, Gump, Strauss, Hauer & Feld, L.L.P.
                                 399 Park Avenue
                            New York, New York 10022
                                 (212) 872-1000
               --------------------------------------------------
                  (Name, Address and Telephone Number of Person
                Authorized to Receive Notices and Communications)

                                February 11, 1997
                    ---------------------------------------
                      (Date of Event which Requires Filing
                               of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box [_].

Check the following box if a fee is being paid with the statement [_]. (A fee is
not required only if the reporting person:  (1) has a previous statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7)

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter disclosure
provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



                         Continued on following page(s)
                                Page 1 of 9 Pages




<PAGE>


                                                               Page 2 of 9 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               Soros Fund Management LLC

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [x]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               Delaware

                      7      Sole Voting Power
 Number of                          660,000
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          0
    Each
  Reporting           9      Sole Dispositive Power
   Person                           660,000
    With
                      10     Shared Dispositive Power
                                    0

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    660,000

12      Check Box If the Aggregate  Amount in Row (11) Excludes  Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             7.50%

14      Type of Reporting Person*

               OO; IA

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                               Page 3 of 9 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               George Soros  (in the capacity described herein)

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [x]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               United States

                      7      Sole Voting Power
 Number of                          0
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          660,000
    Each
  Reporting           9      Sole Dispositive Power
   Person                           0
    With
                      10     Shared Dispositive Power
                                    660,000

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    660,000

12      Check Box If the Aggregate  Amount in Row (11) Excludes  Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             7.50%

14      Type of Reporting Person*

               IA

                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                               Page 4 of 9 Pages

                                  SCHEDULE 13D

CUSIP No. 22054300

1       Name of Reporting Person
        S.S. or I.R.S. Identification No. of Above Person

               Stanley F. Druckenmiller (in the capacity described herein)

2       Check the Appropriate Box If a Member of a Group*
                                            a.  [_]
                                            b.  [x]

3       SEC Use Only

4       Source of Funds*

               Not applicable

5       Check Box If Disclosure  of Legal  Proceedings  Is Required  Pursuant to
        Items 2(d) or 2(e) [_]

6       Citizenship or Place of Organization

               United States

                      7      Sole Voting Power
 Number of                          0
   Shares
Beneficially          8      Shared Voting Power
  Owned By                          660,000
    Each
  Reporting           9      Sole Dispositive Power
   Person                           0
    With
                      10     Shared Dispositive Power
                                    660,000

11      Aggregate Amount Beneficially Owned by Each Reporting Person

                                    660,000

12      Check Box If the Aggregate Amount in Row (11) Excludes Certain Shares*
        [_]

13      Percent of Class Represented By Amount in Row (11)

                             7.50%

14      Type of Reporting Person*

               IA
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


<PAGE>


                                                               Page 5 of 9 Pages

               This  Amendment No. 4 to Schedule 13D relates to shares of Common
Stock,  $0.001 par value per share (the  "Shares"),  of Cortex  Pharmaceuticals,
Inc. (the  "Issuer").  This  Amendment No. 4  supplementally  amends the initial
statement on Schedule 13D dated  November  12, 1993 and all  amendments  thereto
(collectively,  the "Initial  Statement")  filed by one of the Reporting Persons
(as  defined  herein).  This  Amendment  No. 4 is being  filed by the  Reporting
Persons to report  the  recent  disposition  of Shares  held for the  account of
Quantum  Partners  LDC,  a Cayman  Islands  exempted  limited  duration  company
("Quantum Partners"), the principal operating subsidiary of Quantum Fund N.V., a
Netherlands  Antilles  company  ("Quantum  Fund"),  as a  result  of  which  the
percentage  of  Shares of which the  Reporting  Persons  may be deemed to be the
beneficial owner has decreased by more than one percent.  Capitalized terms used
herein but not defined  herein shall have the  meanings  ascribed to them in the
Initial Statement. The Initial Statement is supplementally amended as follows.

Item 2.        Identity and Background.

               This statement is being filed on behalf of Soros Fund  Management
LLC, a Delaware  limited  liability  company ("SFM LLC"), Mr. George Soros ("Mr.
Soros") and Mr. Stanley F. Druckenmiller ("Mr. Druckenmiller," and together with
SFM LLC and Mr. Soros,  the  "Reporting  Persons").  This  statement  relates to
Shares held for the account of Quantum Partners.

               Updated information  concerning the Managing Directors of SFM LLC
is attached hereto as Annex A and incorporated herein by reference.

Item 5.        Interest in Securities of the Issuer.

               (a) The aggregate number of Shares of which each of the Reporting
Persons  may be deemed the  beneficial  owner is 660,000  Shares  (approximately
7.50% of the total number of Shares outstanding).

               (b) (i)  Pursuant to the terms of the  contract  between  Quantum
Fund and SFM LLC,  SFM LLC may be deemed to have sole power to direct the voting
and disposition of the 660,000 Shares held for the account of Quantum Partners.

                    (ii) Pursuant to the terms of the contract  between  Quantum
Fund and SFM LLC and as a result  of the  positions  held by Mr.  Soros  and Mr.
Druckenmiller  with SFM LLC,  each of Mr.  Soros  and Mr.  Druckenmiller  may be
deemed to have shared power to direct the voting and  disposition of the 660,000
Shares held for the account of Quantum Partners.

               (c) Except as disclosed in Item 2 hereof,  which is  incorporated
by reference in this Item 5 and the transactions listed on Annex B hereto, there
have been no  transactions  effected with respect to the Shares since January 1,
1997,  the date of the last filing on Schedule  13D  relating to the Shares,  by
Quantum  Partners or by any of the Reporting  Persons.  All of the  transactions
listed  on  Annex B were  executed  in  routine  brokerage  transactions  in the
over-the-counter market.

               (d) The shareholders of Quantum Partners, including Quantum Fund,
have the right to participate in the receipt of dividends from, or proceeds from
the sale of, the Shares held for the account of Quantum  Partners in  accordance
with their ownership interests in Quantum Partners.

               (e) Not applicable.


<PAGE>


                                                               Page 6 of 9 Pages

Item 7.        Material to be Filed as Exhibits.

               A. Power of Attorney  dated as of January 1, 1997  granted by Mr.
Soros in favor of Mr. Sean C. Warren and Mr. Michael C. Neus (filed as Exhibit A
to  Amendment  No.  3 to  the  Initial  Statement  and  incorporated  herein  by
reference).

               B. Purchase  Agreement dated November 5, 1993, between the Issuer
and  Quantum  Partners  (filed  as  Exhibit  B  to  the  Initial  Statement  and
incorporated herein by reference).

               C. Power of Attorney  dated as of January 1, 1997  granted by Mr.
Druckenmiller  in favor of Mr. Sean C. Warren and Mr.  Michael C. Neus (filed as
Exhibit C to Amendment No. 3 to the Initial Statement and incorporated herein by
reference).

               D. Joint Filing  Agreement dated January 1, 1997 by and among SFM
LLC, Mr. Soros and Mr.  Druckenmiller  (filed as Exhibit D to Amendment No. 3 to
the Initial Statement and incorporated herein by reference).




<PAGE>


                                                               Page 7 of 9 Pages

                                   SIGNATURES

               After  reasonable  inquiry  and to the best of my  knowledge  and
belief,  the  undersigned  certifies  that  the  information  set  forth in this
statement is true, complete and correct.

Date:     February 18, 1997             SOROS FUND MANAGEMENT LLC


                                        By:  /S/ MICHAEL C. NEUS
                                             ----------------------------------
                                             Michael C. Neus
                                             Assistant General Counsel


                                        GEORGE SOROS


                                        By:  /S/ MICHAEL C. NEUS
                                             ----------------------------------
                                             Michael C. Neus
                                             Attorney-in-Fact


                                        STANLEY F. DRUCKENMILLER
                                        

                                        By:  /S/ MICHAEL C. NEUS
                                             ----------------------------------
                                             Michael C. Neus
                                             Attorney-in-Fact



<PAGE>


                                                               Page 8 of 9 Pages

                                     ANNEX A


               The following is a list of all of the persons (other than Stanley
Druckenmiller) who serve as Managing Directors of SFM LLC:



                               Scott K. H. Bessent
                                 Walter Burlock
                                Brian J. Corvese
                               Jeffrey L. Feinberg
                                  Arminio Fraga
                                 Gary Gladstein
                                Robert K. Jermain
                                 David N. Kowitz
                               Alexander C. McAree
                                  Paul McNulty
                              Gabriel S. Nechamkin
                                   Steven Okin
                                  Dale Precoda
                               Lief D. Rosenblatt
                                 Mark D. Sonnino
                             Filiberto H. Verticelli
                                 Sean C. Warren

Each of the  above-listed  persons is a United States  citizen  whose  principal
occupation  is serving as Managing  Director of SFM LLC, and each has a business
address c/o Soros Fund Management LLC, 888 Seventh Avenue, 33rd Floor, New York,
New York 10106.

To the best of the Reporting Persons' knowledge:

          (a) None of the above persons holds any Shares.

          (b)  None  of the  above  persons  has  any  contracts,  arrangements,
understandings or relationships with respect to the Shares.





<PAGE>

<TABLE>

                                                                                     Page 9 of 9 Pages
        
<CAPTION>
                                                ANNEX B

                              RECENT TRANSACTIONS IN THE COMMON STOCK OF
                                     CORTEX PHARMACEUTICALS, INC.


                                Date of          Nature of
For the Account of            Transaction       Transaction      Number of Shares     Price Per Share
- ------------------          -------------       -----------      ----------------     ---------------
<S>                        <C>                 <C>              <C>                  <C>

Quantum Partners LDC/1/         1/3/97             SELL               14,500                 4.099

                                1/6/97             SELL                5,500                 4.352

                                1/10/97            SELL               12,000                 4.012

                                1/13/97            SELL               13,800                 3.976

                                2/11/97            SELL               50,000                 4.924

                                2/11/97            SELL               40,900                 4.916

                                2/11/97            SELL                5,000                 4.664

                                2/12/97            SELL                2,000                 4.601

                                2/13/97            SELL               15,100                 4.549

                                2/14/97            SELL               35,000                 4.392

                                2/14/97            SELL                3,600                 4.381

                                2/18/97            SELL               17,600                 4.098




- ------------

/1/     Transactions effected at the direction of SFM LLC.
</TABLE>


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