SYNETIC INC
S-3, 1997-02-04
PLASTICS PRODUCTS, NEC
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<PAGE>
 
   As Filed with the Securities and Exchange Commission on February 4, 1997.
                                                     REGISTRATION NO. 333-
================================================================================


                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                             ---------------------

                                    FORM S-3
                             REGISTRATION STATEMENT
                                     UNDER
                           THE SECURITIES ACT OF 1933

                             ---------------------

                                 SYNETIC, INC.
             (Exact name of Registrant as specified in its charter)

            DELAWARE                                      22-2975182
  (State or other jurisdiction                         (I.R.S. Employer
of incorporation or organization)                     Identification No.)

                     669 RIVER DRIVE, RIVER DRIVE CENTER II
                        ELMWOOD PARK, NEW JERSEY  07407
                                 (201) 703-3400

  (Address, including Zip Code, and telephone number, including area code, of
                   Registrant's principal executive offices)

                              ------------------

                             CHARLES A. MELE, ESQ.
                        VICE PRESIDENT--GENERAL COUNSEL
                                 SYNETIC, INC.
                     669 RIVER DRIVE, RIVER DRIVE CENTER II
                        ELMWOOD PARK, NEW JERSEY  07407
                                 (201) 703-3400
 (Name, address, including Zip Code, and telephone number, including area code,
                             of agent for service)

                              ------------------

                                   Copies to:
   CREIGHTON O'M. CONDON, ESQ.                         ALAN JAKIMO, ESQ.
    DAVID J. BEVERIDGE, ESQ.                           BROWN & WOOD LLP
       SHEARMAN & STERLING                         ONE WORLD TRADE CENTER
      599 LEXINGTON AVENUE                        NEW YORK, NEW YORK  10048
    NEW YORK, NEW YORK  10022                           (212) 839-5300
        (212) 848-4000

                              ------------------

     APPROXIMATE DATE OF COMMENCEMENT OF PROPOSED SALE OF THE SECURITIES TO THE
PUBLIC:  As soon as practicable after this Registration Statement becomes
effective.
     If the only securities being registered on this Form are being offered
pursuant to dividend or interest reinvestment plans, please check the following
box. [ ]

     If any of the securities being registered on this Form are to be offered on
a delayed or continuous basis pursuant to Rule 415 under the Securities Act of
1933, other than securities offered only in connection with dividend or interest
reinvestment plans, check the following box.  [ ]

     If this Form is filed to register additional securities for an offering
pursuant to Rule 462(b) under the Securities Act, please check the following box
and list the Securities Act registration statement number of the earlier
effective registration statement for the same offering.  [ ]

     If this Form is a post-effective amendment filed pursuant to Rule 462(c)
under the Securities Act, check the following box and list the Securities Act
registration statement number of the earlier effective registration statement
for the same offering.  [ ]

     If delivery of the prospectus is expected to be made pursuant to Rule 434,
please check the following box.  [ ]
<PAGE>
 
                        CALCULATION OF REGISTRATION FEE
<TABLE>
<CAPTION>
=============================================================================================================== 
                                                      Proposed Maximum    Proposed Maximum        Amount of
      Title of Each Class of          Amount to be     Offering Price    Aggregate Offering   Registration Fee
    Securities to be Registered        Registered     Per Debenture (1)       Price (1)
- --------------------------------------------------------------------------------------------------------------- 
<S>                                  <C>              <C>                <C>                  <C>
 
___% Convertible Subordinated        $115,000,000(2)        100%            $115,000,000          $34,849
 Debentures due 2007                                                    
- --------------------------------------------------------------------------------------------------------------- 
Common Stock, $.01 par value,              (3)               --                  --                 None
 issuable upon conversion of the                                        
 ___% Convertible Subordinated
 Debentures due 2007
=============================================================================================================== 
</TABLE>
 (1) Estimated solely for the purpose of calculating the registration fee.
 (2) Including up to $15,000,000 aggregate principal amount of Debentures that
     may be issued upon exercise of the Underwriter's over-allotment option.
 (3) Such currently indeterminable number as may be issuable upon conversion of
     the Debentures.

                             --------------------

     THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR
DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL
FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION
STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(a) OF
THE SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME
EFFECTIVE ON SUCH DATE AS THE SECURITIES AND EXCHANGE COMMISSION, ACTING
PURSUANT TO SAID SECTION 8(a), MAY DETERMINE.
================================================================================
<PAGE>

++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
INFORMATION CONTAINED HEREIN IS SUBJECT TO COMPLETION OR AMENDMENT. A 
REGISTRATION STATEMENT RELATING TO THESE SECURITIES HAS BEEN FILED WITH THE 
SECURITIES AND EXCHANGE COMMISSION. THESE SECURITIES MAY NOT BE SOLD NOR MAY 
OFFERS TO BUY BE ACCEPTED PRIOR TO THE TIME THE REGISTRATION STATEMENT BECOMES 
EFFECTIVE. THIS PROSPECTUS SHALL NOT CONSTITUTE AN OFFER TO SELL OR THE 
SOLICITATION OF AN OFFER TO BUY NOR SHALL THERE BE ANY SALE OF THESE SECURITIES 
IN ANY STATE IN WHICH SUCH OFFER, SOLICITATION OR SALE WOULD BE UNLAWFUL PRIOR 
TO REGISTRATION OR QUALIFICATION UNDER THE SECURITIES LAWS OF ANY SUCH STATE.
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++




 
                             SUBJECT TO COMPLETION
                 PRELIMINARY PROSPECTUS DATED FEBRUARY __, 1997
PROSPECTUS
- ----------
                                  $100,000,000

                                 SYNETIC, INC.
                   % CONVERTIBLE SUBORDINATED DEBENTURES DUE 2007
              -----                                              
                            ------------------------
     The __% Convertible Subordinated Debentures ("Debentures") to be issued by
Synetic, Inc. ("Synetic" or the "Company") will be convertible, at the option of
the holder, at any time prior to maturity, unless previously redeemed or
repurchased, into shares of Common Stock, $.01 par value ("Common Stock"), of
the Company at a conversion price of $      per share of Common Stock
                                      -----
(equivalent to a conversion rate of     shares per $1,000 principal amount of
                                    ---
Debentures), subject to adjustment in certain events.  The Common Stock is
traded on the Nasdaq National Market under the symbol "SNTC".  On January 31,
1997 the last sale price of the Common Stock as reported on the Nasdaq National
Market was $48 1/2 per share.

     Interest on the Debentures will be payable on August 15 and February 15 of
each year commencing August 15, 1997. The Debentures will be redeemable at any
time on or after February 15, 2000 at the option of the Company, in whole or in
part, at the redemption prices set forth herein, plus accrued and unpaid
interest. The Debentures are unsecured and subordinated to present and future
Senior Debt (as defined herein) of the Company. As of the date of this
Prospectus, the Company had no Senior Debt outstanding. The Company is a holding
company and, accordingly, the Debentures will be effectively subordinated to all
indebtedness and other liabilities of subsidiaries of the Company. The Indenture
contains no limitation on the amount of indebtedness that may be incurred by the
Company and its subsidiaries. The Debentures are required to be repurchased at
the option of the holder if a Designated Event (as defined herein) occurs at
100% of the principal amount thereof plus accrued interest. See "Description of
Debentures."

     Up to $10,000,000 aggregate principal amount of the Debentures offered
hereby will be reserved for sale at the initial offering price to certain
directors, officers and employees of, and consultants to, the Company and its
subsidiaries.

     The Company intends to make application to list the Debentures on the
Nasdaq National Market.

                                ----------------

     THIS OFFERING INVOLVES A HIGH DEGREE OF RISK.  SEE "RISK FACTORS" BEGINNING
ON PAGE 8 FOR A DISCUSSION OF CERTAIN FACTORS WHICH SHOULD BE CONSIDERED BY
PROSPECTIVE PURCHASERS OF THE DEBENTURES OFFERED HEREBY.

                                ---------------

    THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES
         AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR
            HAS THE SECURITIES AND EXCHANGE COMMISSION OR ANY STATE
               SECURITIES COMMISSION PASSED UPON THE ACCURACY OR
                ADEQUACY OF THIS PROSPECTUS.  ANY REPRESENTATION
                     TO THE CONTRARY IS A CRIMINAL OFFENSE.
<TABLE>
<CAPTION>
 
================================================================================
                   Price to             Underwriting     Proceeds to
                   Public(1)             Discount(2)     Company(1)(3)
- --------------------------------------------------------------------------------
<S>              <C>                    <C>              <C>
 
Per Debenture       ____%                   ____%            ____%
- --------------------------------------------------------------------------------
Total(4)         $__________             $_________      $__________
================================================================================
</TABLE>
<PAGE>
 
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
INFORMATION CONTAINED HEREIN IS SUBJECT TO COMPLETION OR AMENDMENT. A 
REGISTRATION STATEMENT RELATING TO THESE SECURITIES HAS BEEN FILED WITH THE 
SECURITIES AND EXCHANGE COMMISSION. THESE SECURITIES MAY NOT BE SOLD NOR MAY 
OFFERS TO BUY BE ACCEPTED PRIOR TO THE TIME THE REGISTRATION STATEMENT BECOMES 
EFFECTIVE. THIS PROSPECTUS SHALL NOT CONSTITUTE AN OFFER TO SELL OR THE 
SOLICITATION OF AN OFFER TO BUY NOR SHALL THERE BE ANY SALE OF THESE SECURITIES 
IN ANY STATE IN WHICH SUCH OFFER, SOLICITATION OR SALE WOULD BE UNLAWFUL PRIOR 
TO REGISTRATION OR QUALIFICATION UNDER THE SECURITIES LAWS OF ANY SUCH STATE.
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++

(1) Plus accrued interest, if any, from the date of initial issuance.

(2) The Company has agreed to indemnify the Underwriter against certain
    liabilities, including certain liabilities under the Securities Act of 1933,
    as amended. See "Underwriting."
(3) Before deducting expenses payable by the Company estimated at $_______.

(4) The Company has granted the Underwriter an option, exercisable at any time
    within 30 days after the date hereof, to purchase up to an additional
    $15,000,000 aggregate principal amount of Debentures on the terms set forth
    above to cover over-allotments, if any. If the Underwriter exercises such
    option in full, the total Price to Public, Underwriting Discount and
    Proceeds to Company will be $__________, $_________, and $__________,
    respectively. See "Underwriting."

                                _______________

     The Debentures are offered by the Underwriter, subject to prior sale, when,
as and if issued to and accepted by it, subject to approval of certain legal
matters by counsel for the Underwriter and certain other conditions.  The
Underwriter reserves the right to withdraw, cancel or modify such offer and to
reject orders in whole or in part.  It is expected that delivery of the
Debentures will be made in New York, New York on or about ____________, 1997.

                                _______________

                              MERRILL LYNCH & CO.

                                _______________

               The date of this Prospectus is ___________, 1997.
<PAGE>
 
     THIS PROSPECTUS INCORPORATES DOCUMENTS BY REFERENCE WHICH ARE NOT PRESENTED
HEREIN OR DELIVERED HEREWITH.  THE COMPANY WILL PROVIDE WITHOUT CHARGE TO EACH
PERSON, INCLUDING EACH BENEFICIAL OWNER, TO WHOM THIS PROSPECTUS IS DELIVERED,
UPON THE WRITTEN OR ORAL REQUEST OF SUCH PERSON, A COPY OF ANY OR ALL DOCUMENTS
THAT ARE INCORPORATED HEREIN BY REFERENCE (OTHER THAN EXHIBITS, UNLESS SUCH
EXHIBITS ARE SPECIFICALLY INCORPORATED BY REFERENCE IN SUCH DOCUMENTS).
REQUESTS SHOULD BE DIRECTED TO VICTOR L. MARRERO, VICE PRESIDENT--FINANCE,
SYNETIC, INC., 669 RIVER DRIVE, RIVER DRIVE CENTER II, ELMWOOD PARK, NEW JERSEY
07407, TELEPHONE (201) 703-3400.

                   _________________________________________

     IN CONNECTION WITH THIS OFFERING, THE UNDERWRITER MAY OVER-ALLOT OR EFFECT
TRANSACTIONS WHICH STABILIZE OR MAINTAIN THE MARKET PRICE OF THE DEBENTURES
OFFERED HEREBY, THE COMMON STOCK OF THE COMPANY, OR EITHER OF THEM AT LEVELS
ABOVE THOSE WHICH MIGHT OTHERWISE PREVAIL IN THE OPEN MARKET.  SUCH TRANSACTIONS
MAY BE EFFECTED ON THE NASDAQ NATIONAL MARKET OR OTHERWISE.  SUCH STABILIZING,
IF COMMENCED, MAY BE DISCONTINUED AT ANY TIME.

                   _________________________________________

                             AVAILABLE INFORMATION

     The Company is subject to the informational requirements of the Securities
Exchange Act of 1934, as amended (the "Exchange Act"), and in accordance
therewith, files reports, proxy and information statements and other information
with the Securities and Exchange Commission (the "Commission").  Such reports,
proxy and information statements and other information filed by the Company can
be inspected and copied, at prescribed rates, at the public reference facilities
of the Commission at Judiciary Plaza, 450 Fifth Street, N.W., Room 1024,
Washington, D.C. 20549, and at the regional offices of the Commission located at
Seven World Trade Center, Suite 1300, New York, New York 10048 and 500 West
Madison Street, Suite 1400, Chicago, Illinois 60661.  Copies of such material
may also be obtained, at prescribed rates, by writing to the Public Reference
Section of the Commission at Judiciary Plaza, 450 Fifth Street, N.W.,
Washington, D.C. 20549.  In addition, the Company is required to file electronic
versions of these documents with the Commission through the Commission's
Electronic Data Gathering, Analysis and Retrieval (EDGAR) system.  The
Commission maintains a World Wide Web site at http://www.sec.gov that contains
reports, proxy and information statements and other information regarding
registrants that file electronically with the Commission.  In addition, the
Company's Common Stock is quoted on the Nasdaq National Market System.  Reports,
proxy and information statements and other information concerning the Company
can be inspected at the offices of the National Association of Securities
Dealers, Inc., 1735 K Street, N.W., Washington, D.C. 20006.

     The Company has filed with the Commission a registration statement on Form
S-3 (together with all amendments, exhibits and schedules thereto, the
"Registration Statement") under the Securities Act of 1933, as amended (the
"Securities Act"), with respect to the Debentures offered hereby.  This
Prospectus, which constitutes a part of the Registration Statement, does not
contain all of the information set forth in the Registration Statement, certain
parts of which are omitted in accordance with the rules and regulations of the
Commission.  For further information with respect to the Company and the
Debentures, reference is made to the Registration Statement.  Statements
contained in the Prospectus as to the contents of any contract, agreement or
other document referred to are not necessarily complete.  With respect to each
such contract, agreement or other document filed as an exhibit to the
Registration Statement, reference is made to the exhibit for a complete
description of the matter involved, and each such statement shall be deemed
qualified in its entirety by such reference to such contract, agreement or other
document.  The Registration Statement may be inspected without charge at the
principal office of the Commission in Washington, D.C. and copies of all or any
part thereof may be obtained from the Commission at prescribed rates.
<PAGE>
 
                INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

     The following documents have been filed with the Commission by the Company
(Commission file number 0-17822) pursuant to the Exchange Act and are hereby
incorporated by reference in this Prospectus:

          (i)    The Company's Annual Report on Form 10-K for the fiscal year
                 ended June 30, 1996 (the "1996 10-K");

          (ii)   The Company's Quarterly Reports on Form 10-Q for the fiscal
                 quarters ended September 30, 1996 and December 31, 1996 (the
                 "Second Quarter 10-Q"); and

          (iii)  The Company's Current Reports on Form 8-K filed with the
                 Commission on December 31, 1996 and January 24, 1997.

     All documents filed by the Company pursuant to Section 13(a), 13(c), 14 or
15(d) of the Exchange Act subsequent to the date of this Prospectus and prior to
the termination of the offering of the Debentures shall be deemed to be
incorporated by reference in this Prospectus and to be made a part hereof from
their respective dates of filing.  Any statement contained in any document
incorporated or deemed to be incorporated by reference herein shall be deemed to
be modified or superseded for purposes of this Prospectus to the extent that a
statement contained herein or in any other subsequently filed document that is
also deemed to be incorporated by reference herein modifies or supersedes such
statement.  Any such statement so modified or superseded shall not be deemed,
except as so modified or superseded, to constitute a part of this Prospectus.

                   _________________________________________

                                       2
<PAGE>
 
                              PROSPECTUS SUMMARY

     The following summary information is qualified in its entirety by, and
should be read in conjunction with, the more detailed information and financial
statements, including the notes thereto, appearing in the documents incorporated
herein by reference or elsewhere in this Prospectus.  Except where otherwise
indicated, all information in this Prospectus assumes that the Underwriter's
over-allotment option will not be exercised.  Unless otherwise indicated by the
context, all references in this Prospectus to the "Company" include,
collectively, the Company and its subsidiaries.  This Prospectus contains, under
the captions "Business--Plastics Technologies Business--General," "Business--
Healthcare Communications Business," "Risk Factors--New Business Area--
Healthcare Communications," "--Government Regulation of Healthcare," "--
Reliance on Rapidly Changing Technology" and elsewhere and incorporates by
reference certain forward-looking statements and information relating to the
Company that are based on the beliefs of the Company's management as well as
assumptions made by and information currently available to the Company's
management.  When used in this Prospectus or the documents incorporated by
reference, the words "anticipate," "believe," "estimate," "expect" and similar
expressions, as they relate to the Company or the Company's management, are
intended to identify forward-looking statements.  Such statements reflect the
current view of the Company with respect to future events and are subject to
certain risks, uncertainties and assumptions.  These risks may include product
demand and market acceptance risks, the feasibility of developing commercially
profitable Internet healthcare products and services, the effect of economic
conditions, user acceptance, the impact of competitive products, services and
pricing and product development, commercialization and technological
difficulties.  See "Risk Factors."   Should one or more of these risks or
uncertainties materialize, or should underlying assumptions prove incorrect,
actual results may vary materially from those described herein as anticipated,
believed, estimated or expected.  The Company does not intend to update these
forward-looking statements.


                                  THE COMPANY

     Synetic, Inc. operates in two principal lines of business, plastics
technologies and healthcare communications.  Porex Technologies Corp. (together
with its subsidiaries, "Porex"), a wholly owned subsidiary of the Company,
designs, manufactures and distributes porous and solid plastic components and
products used in healthcare, industrial and consumer applications.  Through
internal development efforts and its recent acquisitions, the Company is
building a new area of business relating to the use of Internet/Intranet
technology ("Internet technology") to expand and enhance the channels of
communication in the healthcare industry.

     Plastics Technologies Business.  Porex's principal products, which
incorporate porous plastics, are used to filter, wick, drain, vent or control
the flow of fluids or gases.  A large percentage of Porex's products are sold to
other manufacturers for incorporation into their products.  The Company believes
Porex's principal strengths to be its manufacturing processes, quality control
and relationships with distributors of its proprietary health care products.
Porex's health care products include proprietary products manufactured and sold
under Porex's trade names.  These products are sold for clinical and
medical/surgical use in hospitals, clinics, physicians' offices and
laboratories.  Porex also manufactures and sells a line of plastic vials and
produces components made to the specifications of original equipment
manufacturers for incorporation into their healthcare products.  Porex's
industrial and consumer products consist primarily of custom-manufactured
components made for manufacturers of industrial and consumer products. As a
result of the Company's development activities, the Company anticipates future
opportunities in several areas of Porex's business, which may include drug-
delivery systems, personal care products and micro-electronics.

                                       3
<PAGE>
 
     Healthcare Communications Business.  The Company's objective in its
healthcare communications business is to use Internet technology to create the
most influential interactive health services channel linking physicians with the
payors, suppliers and consumers of healthcare in order to control healthcare
costs and improve patient outcomes. A key element of the Company's strategy will
be to deploy via the public Internet and private Intranets, a suite of
communications and transaction software that would enable physicians and their
staffs to perform high volume, routine transactions in a uniform manner for all
patients.  The Company seeks to integrate payor-specific content, such as
benefit rules and treatment guidelines, with patient-specific information at the
point of care, thereby creating significant value for all participants. There is
no specific time frame for the Company's first commercial introduction of its
products and services, and the Company anticipates that it will incur
significant expenses in connection with the development of these products and
services. The provision of products and services using Internet technology in
the healthcare communications industry is a developing business. See "Risk
Factors."

     The Company recently completed the acquisition of two businesses in the
healthcare communications area -- Avicenna Systems Corp. ("Avicenna") and
CareAgents, Inc. ("CareAgents").  See "Business--Healthcare Communications
Business--Recent Acquisitions."

     Acquisition Program.  The Company maintains an acquisition program and
intends to concentrate its acquisition efforts in businesses which are
complementary to the Company's healthcare communications strategy. This
emphasis, however, is not intended to limit in any manner the Company's ability
to pursue acquisition opportunities in other healthcare-related businesses or in
other industries. See "Risk Factors--Acquisition Program" and "Business--
Acquisition Program."

          The Company is a Delaware corporation and was incorporated in 1989.
Its principal offices are located at 669 River Drive, River Drive Center II,
Elmwood Park, New Jersey 07407, and its telephone number is (201) 703-3400.

                                  THE OFFERING

The Debentures...........   $100,000,000 aggregate principal amount
                            ($115,000,000 aggregate principal amount if the
                            Underwriter's over-allotment option is exercised in
                            full) of ___% Convertible Subordinated Debentures
                            due 2007 (the "Debentures").

Maturity.................   The Debentures will mature on February 15, 2007,
                            unless earlier redeemed or converted.

Payment of Interest......   Interest on the Debentures at the rate of __% per
                            annum will be payable semiannually on August 15 and
                            February 15 of each year, commencing on August 15,
                            1997.  Interest will be computed on the basis of a
                            360-day year comprised of twelve 30-day months.

Conversion Rights........   The Debentures will be convertible into Common Stock
                            at the option of the holder at any time prior to
                            maturity, unless previously redeemed, at a
                            conversion price of $_____ per share (equivalent to
                            a conversion rate of ___ shares per $1,000 principal
                            amount of Debentures), subject to adjustment in
                            certain events.

Optional Redemption.....    On or after February 15, 2000, the Company may, upon
                            at least 30 days' notice, redeem the Debentures, in
                            whole or in part, at the redemption prices set forth
                            herein, declining to par on or after

                                       4
<PAGE>
 
                            __________, ____, together with accrued interest.

Change in Control........   The Debentures are required to be repurchased at
                            100% of the principal amount thereof plus accrued
                            and unpaid interest at the option of the holder if a
                            Designated Event (as defined) occurs. See
                            "Description of Debentures--Repurchase at Option of
                            Holder Upon Occurrence of a Designated Event."

Subordination............   The Debentures will be unsecured and subordinated to
                            present and future Senior Debt (as defined herein)
                            of the Company and will be effectively subordinated
                            to all indebtedness and other liabilities of
                            subsidiaries of the Company. As of the date of this
                            Prospectus, the Company had no Senior Debt
                            outstanding and the Company's subsidiaries had no
                            indebtedness for borrowed money. The Indenture
                            contains no limitation on the amount of indebtedness
                            that may be incurred by the Company and its
                            subsidiaries.

Use of Proceeds..........   For general corporate purposes, which may include
                            acquisitions. As of the date of this Prospectus, the
                            Company has no agreement or understanding with a
                            prospective acquisition candidate in respect of a 
                            specific transaction.

Listing..................   The Company intends to make application to list the
                            Debentures on the Nasdaq National Market.  The
                            Company's Common Stock is traded on the Nasdaq
                            National Market under the symbol "SNTC."

                                       5
<PAGE>
 
                             SUMMARY FINANCIAL DATA

               (IN THOUSANDS, EXCEPT PER SHARE DATA AND RATIOS)

     The selected financial data set forth below for the five years in the
period ended June 30, 1996 has been derived from the Consolidated Financial
Statements of the Company, which have been audited by Arthur Andersen LLP,
independent public accountants.  The selected financial data as of and for the
six-month periods ended December 31, 1995 and 1996 are derived from the
unaudited consolidated financial statements of the Company which, in the opinion
of management, include all normal and recurring adjustments necessary to present
fairly the financial position and the results of operations of the Company for
those periods.  The operating results for the six months ended December 31, 1996
are not necessarily indicative of the operating results to be expected for the
full year.  Such information should be read in conjunction with the Consolidated
Financial Statements of the Company and the related notes thereto included in
the 1996 10-K that are incorporated by reference into this Prospectus, the
Second Quarter 10-Q incorporated by reference into this Prospectus and the
unaudited consolidated financial statements of the Company contained elsewhere
in this Prospectus.  The selected financial data for the five years in the
period ended June 30, 1996 has been restated to reflect the Divestiture as
described in "Business--Certain Corporate History".  See "Certain Relationships
and Related Transactions" in the 1996 10-K.

<TABLE>
<CAPTION>
                                                                                                             SIX MONTHS
                                                                                                                ENDED
                                                                 YEAR ENDED JUNE 30,                         DECEMBER 31,
                                            ---------------------------------------------------------  ------------------------
                                               1992       1993       1994          1995          1996       1995       1996
                                               ----       ----       ----          ----          ----       ----       ----
                                                                     (IN THOUSANDS, EXCEPT PER SHARE DATA)                 
<S>                                         <C>        <C>        <C>          <C>            <C>        <C>       <C>            
INCOME STATEMENT DATA                                                                                                            
Net sales.................................   $28,486    $30,645    $33,093       $39,179       $45,128    $21,319    $23,084     
Income from continuing operations before                                                                                         
  provisions for income taxes.............     6,031      5,430      1,080         1,078        13,202      6,251    (21,018)    
Provision for income taxes................     2,151      2,046        411           443         4,617      2,254      2,527     
                                            --------   --------   --------      --------      --------   --------  ---------     
Income from continuing operations.........     3,880      3,384       669A(1)       635A(2)      8,585      3,997    (23,545)(3) 
Income from discontinued operations.......     1,376      2,734      1,823        15,459            --         --         --     
                                            --------   --------   --------      --------      --------   --------  ---------     
                                                                                                                                 
Net income................................   $ 5,256    $ 6,118    $ 2,492       $16,094       $ 8,585    $ 3,997   $(23,545)    
                                            ========   ========   ========      ========      ========   ========  =========     
Net income per share (4):                                                                                                        
  Continuing operations...................     $0.24      $0.19      $0.04         $0.04         $0.48      $0.22     $(1.28)    
  Discontinued operations.................      0.09       0.16       0.10          0.89            --         --         --     
                                            --------   --------   --------      --------      --------   --------  ---------     
Net income per share (5)..................     $0.33   $   0.35      $0.14         $0.93         $0.48      $0.22     $(1.28)    
                                            ========   ========   ========      ========      ========   ========  =========     
                                                                                                                                 
Ratio of earnings to fixed charges(6).....      2.7x       1.9x       1.3x          3.1x        125.5x     191.4x     144.1x     
<CAPTION>  
                                                                                                                  AS OF
                                                                     AT JUNE 30,                             DECEMBER 31, 1996
                                            ---------------------------------------------------------      --------------------
                                               1992       1993       1994          1995          1996      ACTUAL   AS ADJUSTED(7)
                                               ----       ----       ----          ----          ----      ------   -----------
<S>                                         <C>        <C>        <C>          <C>            <C>        <C>       <C>      
BALANCE SHEET DATA
Working capital...........................  $ 44,350   $ 65,673   $ 64,625      $105,279      $166,328    $169,644    $  265,644  
Net assets of discontinued                                                                                                 
  operations..............................    25,352     52,548     55,882            --            --          --            -- 
Total assets..............................   163,011    189,494    194,009       188,174       199,592     210,713       312,213
Long term debt, less                                                                                                       
  current portion.........................    81,714     81,058     80,716            --            --          --       100,000  
Stockholders' equity......................    74,056    102,378    105,130       166,832       181,089     183,501       183,501  
- -------------------
</TABLE>

(1) For the fiscal year ended June 30, 1994, includes a non-recurring charge of
    $(372) or $(.02) per share related to one-time payments made to certain
    executive officers in conjunction with the acquisition of the Company's
    former parent.
(2) For the fiscal year ended June 30, 1995 includes:  (i) a non-recurring
    charge of $(3,683) or $(.21) per share primarily related to the award of
    stock options to certain officers in connection with the completion of the
    sale of the institutional pharmacy business and the purchase of the shares
    of Company stock owned by Merck & Co. and (ii) a non-recurring charge of
    $(1,049) or $(.06) per share, related to the conversion and redemption of
    the Company's debentures in February 1995.  See "Business--Certain Corporate
    History."
(3) For the six months ended December 31, 1996, includes a non-recurring charge
    of $(28,600) or $(1.55) per share allocated to purchased research and
    development costs in conjunction with the purchase of Avicenna Systems
    Corp., which, in accordance with generally accepted accounting principles,
    has been charged to expense.  See "Business--Healthcare Communications
    Business--Recent Acquisitions".

                                       6
<PAGE>
 
(4) Restated to reflect a two-for-one stock split effected on February 26, 1993.
(5) No cash dividends were declared by the Company during the periods presented
    above.
(6) Earnings used in computing the ratio of earnings to fixed charges consist of
    earnings from continuing operations before taxes, non-recurring items and
    fixed charges. Fixed charges consist of interest expense, amortization of
    debt issuance costs and the estimated interest element of rental payments.
    Because the Debentures will have an annual interest requirement of
    $________________, in the future the ratio of earnings to fixed charges may
    decline.
(7) As adjusted to reflect the issuance of $100 million aggregate principal 
    amount of the Debentures offered hereby.

                                       7
<PAGE>
 
                                 RISK FACTORS

     Prior to making an investment decision with respect to the Debentures
offered hereby, prospective investors should carefully consider the specific
factors set forth below, together with all of the other information appearing
herein, in light of their particular investment objectives and financial
circumstances.

NEW BUSINESS AREA--HEALTHCARE COMMUNICATIONS

     Initial Development Phase.  The Company is in the initial development phase
of offering products and services to provide inter-enterprise connectivity to
payors and providers in the healthcare industry.  The provision of products and
services using Internet technology in the healthcare communications industry is
a developing business. There is no specific time frame for the Company's first
commercial introduction of its products and services, and the Company
anticipates that it will incur significant expenses in connection with the
development of these products and services. There can be no assurance that these
products and services will be successfully developed by the Company. Avicenna,
the Company's first acquisition in this area, has operated at a loss since its
inception two years ago, and as of November 30, 1996 had an unaudited
accumulated deficit of approximately $3,100,000. CareAgents, the Company's
second acquisition in this area, founded in 1996, is a start-up company with a
very limited operating history. The Company is pursuing the development of its
healthcare communications business through the use of its internal resources as
well as pursuing the acquisition of complementary businesses. The Company
anticipates that it may enter into acquisitions, joint ventures, strategic
alliances or other business combinations. These transactions may materially
change the nature and scope of this business. There can be no assurance that the
Company will succeed in consummating such transactions or that such transactions
will ultimately provide the Company with the ability to offer the products and
services described.

Uncertainty of Market Acceptance. As is typical in a developing business, demand
and market acceptance for new and unproven products and services are subject to
a high level of uncertainty. Achieving market acceptance for the Company's
products and services will require substantial marketing efforts and expenditure
of significant funds to create awareness and demand by participants in the
healthcare industry. No assurances can be given that the Company's effort in
establishing such products and services will be successful, that the Company
will be able to succeed in positioning its services as a preferred method for
healthcare communications, that there will be significant market acceptance for
its products and services or that any pricing strategy developed by the Company
will be economically viable or acceptable to the market.

Expected Losses.  Synetic expects to continue to incur significant research and
development expenses and incur additional operating losses in connection with
its healthcare communications business until the products and services are
successfully developed and marketed.  The rate of aggregate expenditures at
Avicenna and CareAgents immediately prior to their acquisition was approximately
$1,600,000 per quarter.  Research and development expenses relating to Avicenna
may be materially greater in the future than current amounts until the Company
successfully develops and markets these products and services.  Synetic
anticipates, however, that such research and development expenses will not
exceed $2,500,000 per fiscal quarter for the third and fourth quarters of the
current fiscal year ending June 30, 1997 and will not result in net losses for
Synetic on a consolidated basis for the current fiscal year (excluding the non-
recurring charges for purchased research and development costs relating to the
acquisition of Avicenna and CareAgents; see "Business--Healthcare Communications
Business"), or for either of the fiscal quarters ending March 31, 1997 or June
30, 1997.  There can be no assurance as to when, and to what extent, if any, the
healthcare communications business of the Company will become profitable.

GOVERNMENT REGULATION OF HEALTHCARE

     Participants in the healthcare industry are subject to extensive and
frequently changing regulation under numerous laws administered by governmental
entities at the federal, state and local levels.  Many current laws and
regulations, when enacted, did not anticipate the methods of healthcare
communication under development by the Company.  The Company believes, however,
that these laws and regulations will nonetheless be applied to the Company's
healthcare communications business.  Accordingly, the Company's healthcare
communications business

                                       8
<PAGE>
 
may be affected by current regulations as well as future regulations
specifically targeted to this new segment of the healthcare industry.

     Current laws and regulations which may affect the healthcare communications
business include (i) the regulation of confidential patient medical record
information, (ii) laws relating to the electronic transmission of prescriptions
from physicians' offices to pharmacies, (iii) regulations governing the use of
software applications in the diagnosis, cure, treatment, mitigation or
prevention of disease and (iv) laws or regulations relating to the relationships
between or among healthcare providers.   The Company expects to conduct its
healthcare communications business in substantial compliance with all material
federal, state and local laws and regulations governing its operations.
However, the impact of regulatory developments in the healthcare industry is
complex and difficult to predict, and there can be no assurance that the Company
will not be materially adversely affected by existing or new regulatory
requirements or interpretations.

RELIANCE ON RAPIDLY CHANGING TECHNOLOGY

     All businesses which rely on Internet technology, including the healthcare
communications business described herein, are subject to rapid technological
change, changing customer needs, frequent new product introductions and evolving
industry standards. In addition, as the communications, computer and software
industries continue to experience rapid technological change, the Company must
be able to quickly and successfully adapt its products and services so that they
adapt to such changes. There can be no assurance that the Company will not
experience difficulties that could delay or prevent the successful development
and introduction of its healthcare communications products and services. The
Company's inability to respond to technological changes in a timely and cost-
effective manner could have a material adverse effect on the Company's business,
financial condition and results of operations. Moreover, there can be no
assurance that technologically superior products and services will not be
developed by competitors, or that any such products and services will not have
an adverse effect upon the Company's operating results.

COMPETITION IN HEALTHCARE COMMUNICATIONS

     The Company is not aware of any business which currently provides the scope
and breadth of the healthcare communications products and services currently
being developed by the Company.  However, various companies including, but not
limited to, certain physician office management information systems companies,
EDI/data networking companies, online medical information service companies, and
systems integration companies, some of which may have greater resources than the
Company, have announced that they are developing a combination of one or more of
these products and services.  There can be no assurance that such companies will
not develop and successfully market the healthcare communications products and
services described herein in a manner which would have a material adverse effect
on the Company.  See "Business-- Healthcare Communications Business--Business
Strategy."

RISKS OF PRODUCT DEVELOPMENT; PROPRIETARY RIGHTS

     The Company's future success and ability to compete in the healthcare
communications business may be dependent in part upon its proprietary rights to
products and services which it develops.  The Company may rely on a combination
of copyrights, trademarks and trade secrets and contractual restrictions to
protect its content and technology and on similar proprietary rights of its
content and technology providers.  There can be no assurance that the steps
taken by the Company or such providers would be adequate to prevent
misappropriation of their respective proprietary rights or that the Company's
competitors will not independently develop content or technology that are
substantially equivalent or superior.  In addition, there can be no assurance
that licenses for any intellectual property of third parties that might be
required for the Company's products or services would be available on
commercially reasonable terms or at all.  Although the Company intends to take
steps to insure that it is not infringing the proprietary rights of any third
parties, there can be no assurance that patent infringement or other claims will
not be asserted against the Company or one of its content or technology
providers or that such claims

                                       9
<PAGE>
 
will not be successful.  The Company could incur substantial costs and diversion
of management resources with respect to the defense of any such claims.
Furthermore, parties making such claims against the Company or a content or
technology provider could secure a judgment awarding substantial damages, as
well as injunctive or other equitable relief which could effectively block the
Company's ability to provide products or services in certain of its markets.
Such a judgment could have a material adverse effect on the Company's business,
financial condition and results of operations.

GOVERNMENT REGULATION OF POREX

     Porex manufactures and distributes certain medical/surgical devices, such
as plastic and reconstructive surgical implants and tissue expanders, which are
subject to government regulations, including approval procedures instituted by
the Food and Drug Administration.  Future healthcare products may also be
subject to such regulations and approval processes.  Compliance with such
regulations and the process of obtaining approvals can be costly, complicated
and time-consuming, and there can be no assurance that such approvals will be
granted on a timely basis, if ever.  See "Business--Porex--Regulation" in the
1996 10-K.

POTENTIAL LIABILITY RISK AND AVAILABILITY OF INSURANCE

     The products sold by the Company expose it to potential risk for product
liability claims particularly with respect to Porex's life sciences, clinical
and surgical products.  The Company believes that Porex carries adequate
insurance coverage against product liability claims and other risks.  There can
be no assurance, however, that claims in excess of Porex's insurance coverage
will not arise.  In addition, Porex's insurance policies must be renewed
annually.  In 1994, Porex was notified that its insurance carrier would not
renew its then-existing insurance coverage after December 31, 1994 with respect
to actions and claims arising out of Porex's distribution of silicone mammary
implants.  However, Porex has exercised its right to purchase extended reporting
period coverage with respect to such actions and claims.  Such coverage provides
insurance, subject to existing policy limits but for an unlimited time period,
with respect to actions and claims made after December 31, 1994 that are based
on events that occurred during the policy period.  See "--Certain Litigation."
Porex has renewed its insurance coverage with the same carrier for other
liability claims.  Although Porex has been able to obtain adequate insurance
coverage at an acceptable cost in the past and believes that it is adequately
indemnified for products manufactured by others and distributed by it, there can
be no assurance that in the future it will be able to obtain such insurance at
an acceptable cost or be adequately protected by such indemnification.  See
"Business--Porex--Health Care Products" and "Legal Proceedings--Mammary Implant
Litigation" in the 1996 10-K.

CERTAIN LITIGATION

     During the year ended June 30, 1988, Porex began distributing silicone
mammary implants ("implants") in the United States pursuant to a distribution
arrangement (the "Distribution Agreement") with a Japanese manufacturer (the
"Manufacturer").  Because of costs associated with increased government
regulation and examination, Porex's supplier determined to withdraw its implants
from the United States market.  On July 9, 1991, the FDA mandated a recall of
all implants manufactured by companies that elected not to comply with certain
FDA regulations regarding data collection.  Accordingly, Porex notified all of
its customers not to use any implants sold by Porex and to return such implants
to Porex for a full refund.  Porex had ceased offering implants for sale prior
to the recall date.  Porex believes that after accounting for implants returned
to it, the aggregate number of recipients of implants distributed by Porex under
the Distribution Agreement in the United States totals approximately 2,500.

     Since March 1991, Porex has been named as one of many co-defendants in a
number of actions brought by recipients of implants.  One of the pending
actions, Donna L. Turner v. Porex Technologies Corporation, et al., is styled as
a class action.  Certain of the actions against Porex have been dismissed where
it was determined that the implant in question was not distributed by Porex.  In
addition, as of January 31, 1997, 57 claims have been settled on a favorable
basis by the Manufacturer, or by the insurance carriers of Porex, without
material cost to Porex.  As of January 31, 1997, 217 actions and 34 out-of-court
claims were pending against Porex.  Of the 217

                                       10
<PAGE>
 
actions, 100 involve implants identified as distributed by Porex and 84 cases
involve implants identified as not having been distributed by Porex.  In the
remaining 33 actions, the implants have not been identified.  The number of
claims made by individuals during the fiscal year ended June 30, 1996 was
significantly lower than the number of claims made during the fiscal year ended
June 30, 1995.

     The typical case or claim alleges that the individual's mammary implants
caused one or more of a wide range of ailments.  These implant cases and claims
generally raise difficult and complex factual and legal issues and are subject
to many uncertainties and complexities, including, but not limited to, the facts
and circumstances of each particular case or claim, the jurisdiction in which
each suit is brought, and differences in applicable law.  The Company does not
have sufficient information to evaluate each case and claim.

     In 1994, Porex was notified that its insurance carrier would not renew its
then-existing insurance coverage after December 31, 1994 with respect to actions
and claims arising out of Porex's distribution of implants.  However, Porex has
exercised its right, under such policy, to purchase extended reporting period
coverage with respect to such actions and claims.  Such coverage provides
insurance, subject to existing policy limits but for an unlimited time period,
with respect to actions and claims made after December 31, 1994 that are based
on events that occurred during the policy period.  In addition, Porex has other
excess insurance where it has similarly purchased extended reporting period
coverage which by its terms would expire December 31, 1997.  However, Porex
expects to purchase further extended reporting period coverage from the excess
insurers to the extent such coverage is reasonably available.  The Company
believes that its present coverage, together with Porex's insurance policies in
effect on or before December 31, 1994, should provide adequate coverage against
liabilities that could result from actions or claims arising out of Porex's
distribution of implants.  To the extent that certain of such actions and claims
seek punitive and compensatory damages arising out of alleged intentional torts,
such damages, if awarded, may or may not be covered, in whole or in part, by
Porex's insurance policies.  In addition, Porex's recovery from its insurance
carriers is subject to policy limits and certain other conditions.  Porex has
been expensing the retention amount under its policies as incurred.

     The Company believes that Porex has a valid claim for indemnification under
the Distribution Agreement with respect to any liabilities that could result
from pending actions or claims by recipients of implants or any similar actions
or claims that may be commenced in the future.  However, Porex's right to
indemnification is subject to a disagreement with the Manufacturer.  Pending the
resolution of such disagreement, the Manufacturer has been paying a portion of
the costs of the settled claims.

ACQUISITION PROGRAM

     The Company maintains an acquisition program and intends to concentrate its
acquisition efforts on businesses which are complementary to the Company's
healthcare communications strategy, but such emphasis is not intended to limit
in any manner the Company's ability to pursue acquisition opportunities in other
healthcare-related businesses or in other industries. The Company anticipates
that it may enter into acquisitions, joint ventures, strategic alliances or
other business combinations. These transactions may materially change the nature
and scope of the business. Any transactions will be limited, as required by
agreements to which the Company is a party, to areas of business that would not
be competitive with certain businesses of Merck & Co., Inc. and its subsidiaries
or with the Institutional Pharmacies Business (as defined in "Business--Certain
Corporate History"). See "Business--Certain Corporate History" below and
"Certain Relationships and Related Transactions" in the 1996 10-K. Although
management of the Company will endeavor to evaluate the risks inherent in any
particular transaction, there can be no assurance that the Company will properly
ascertain all such risks. In addition, no assurances can be given that the
Company will succeed in consummating any such transactions, that such
transactions will ultimately provide the Company with the ability to offer the
products and services described or that the Company will be able to successfully
manage or integrate any resulting business.

                                       11
<PAGE>
 
     The success of the Company's acquisition program will depend on, among
other things, the availability of suitable candidates, the availability of funds
to finance transactions, and the availability of management resources to oversee
the operation of resulting businesses.  Financing for such transactions may come
from several sources, including, without limitation, (a) cash and cash
equivalents on hand and marketable securities and (b) proceeds from the
incurrence of indebtedness or the issuance of additional Common Stock, preferred
stock, convertible debt or other securities, which could result in substantial
dilution of the percentage ownership of the stockholders of the Company at the
time of any such issuance.  The proceeds from any financing may be used for
costs associated with identifying and evaluating prospective candidates, and for
structuring, negotiating, financing and consummating any such transactions and
for other general corporate purposes.  The Company does not intend to seek
stockholder approval for any such transaction or security issuance unless
required by applicable law or regulation.  Although Mr. Martin J. Wygod,
Chairman of the Board of the Company, has indicated his intention to assist the
Company in its acquisition program by bringing opportunities for potential
transactions to the Company and to assist the Company in negotiating such
transactions and in seeking financing in the event any such transaction were to
be financed by the Company, he is not an officer or an employee of the Company
nor is he required pursuant to any contractual obligation to provide such
support or assistance.  See "Business--Acquisition Program."

DISCRETIONARY USE OF PROCEEDS

     The Company currently intends to use the net proceeds from the sale of the
Debentures for general corporate purposes, which may include acquisitions.  The
Company's management has broad discretion with respect to the specific
application of the net proceeds of this Offering.

HOLDING COMPANY STRUCTURE

     The Company is a holding company that has no significant operations other
than those incidental to its ownership of its Porex and Avicenna subsidiaries.
It is anticipated that future acquisitions will be operated through
subsidiaries. As a holding company, to the extent that the Company would require
funds to meet its debt service and other obligations and such funds are not
available at the holding company level, the Company would be dependent on
dividends or other intercompany transfers of funds from Porex and Avicenna or
such other subsidiaries. Claims of creditors of the Company's subsidiaries,
including trade creditors, generally will have priority as to the assets of such
subsidiaries over the claims of the Company and the holders of the Company's
indebtedness, including the Debentures. The indenture pursuant to which the
Debentures will be issued will not restrict borrowing at either the Company or
the subsidiary level, including borrowings in connection with the Company's
acquisition program. See "Description of Debentures."

SUBORDINATION OF DEBENTURES

     The Debentures will be subordinated to existing and future Senior Debt of
the Company.  As of the date of this Prospectus, the Company had no Senior Debt
outstanding.  The company is a holding company and, accordingly, the Debentures
will be effectively subordinated to all existing and future liabilities of the
Company's subsidiaries.  As of the date of this Prospectus, the Company's
subsidiaries had no indebtedness for borrowed money.  Upon any distribution of
assets of the Company upon any dissolution, winding up, liquidation or
reorganization, the payment of the principal of, premium, if any and interest on
the Debentures will be subordinated to the extent provided in the Indenture in
right of payment to the prior payment in full of all Senior Debt.  By reason of
this provision, in the event of the Company's dissolution or insolvency, holders
of Senior Debt may receive more, ratably, and holders of the Debentures may
receive less, ratably, than the other creditors of the Company.  See
"Description of Debentures--Subordination."

ABSENCE OF AN ESTABLISHED MARKET FOR THE DEBENTURES

     Prior to the offering of the Debentures, there has been no public trading
market for the Debentures.  Although the Company intends to make application to
list the Debentures on the Nasdaq National Market, there can be no assurance
that an active public market for the Debentures will develop or, if a public
market develops, that

                                       12
<PAGE>
 
the market price will exceed the public offering price set forth on the covering
page of this Prospectus.  If an active public trading market for the Debentures
does not develop, the market prices and liquidity of the Debentures may be
adversely affected.  Because the Debentures are convertible into Common Stock,
the prices at which the Debentures trade in the market will likely be affected
by the price of the Company's Common Stock.

SHARES AVAILABLE FOR FUTURE SALE

     The 5,061,857 Wygod Shares (as defined in "Business - Certain Corporate
History") are "restricted securities," within the meaning of Rule 144
promulgated pursuant to the Securities Act ("Rule 144"), subject to the volume
restrictions of Rule 144 but for which the two-year holding period has expired.
In addition, as more fully set forth in "Certain Relationships and Related
Transactions" in the 1996 10-K, the Wygod Shares are subject to certain
restrictions on transfer.  Upon expiration of such restrictions, SN Investors,
L.P. ("SN Investors") may be able to sell without registration under the
Securities Act the number of such shares permitted under Rule 144.  The Company
has granted certain demand registration rights to Mr. Wygod with respect to the
Wygod Shares that are assignable to SN Investors.  Any sales by SN Investors
pursuant to Rule 144 or such registration rights could have a material adverse
effect on the prevailing market price for the Common Stock.   See "Business--
Certain Corporate History" and "Description of Capital Stock--Shares Eligible
for Future Sale."

     As of January 31, 1996, the Company has reserved an aggregate of 7,001,156
shares of Common Stock for issuance pursuant to stock option agreements and
stock option plans and an additional 250,000 shares for issuance upon the
exercise of warrants exercisable after December 23, 1998.  The sale of a
substantial amount of such additional shares of Common Stock following their
issuance could have a material adverse effect on the market price of the Common
Stock.

CERTAIN ANTITAKEOVER EFFECTS

     Provisions in the Certificate of Incorporation of the Company relating to a
staggered Board of Directors, super-majority requirements and delegation of
rights to issue Preferred Stock may have the effect not only of discouraging
tender offers or other stock acquisitions but also of deterring existing
stockholders from making management changes.  See "Description of Capital Stock-
- -Common Stock."

                                       13
<PAGE>
 
                                USE OF PROCEEDS

     The net proceeds from the sale of the Debentures are estimated to be
approximately $_______ ($_______ if the Underwriter's over-allotment option is
exercised in full).  The Company currently intends to use the net proceeds for
general corporate purposes, which may include acquisitions. As of the date of
this Prospectus, the Company has no agreement or understanding with a
prospective acquisition candidate in respect of a specific transaction. Pending
the use of the net proceeds as described above, the Company intends to maintain
the net proceeds in short-term or demand interest-bearing instruments or
accounts. See "Prospectus Summary--The Company" and "Risk Factors--The
Acquisition Program."

                          PRICE RANGE OF COMMON STOCK

     The Common Stock is traded on the Nasdaq National Market under the symbol
SNTC.  The following table sets forth for the periods indicated the high and low
sale prices for the Company's Common Stock as reported by the Nasdaq National
Market.

<TABLE>
<CAPTION>
 
                                                High      Low
                                                ----      ---   
<S>                                            <C>      <C>
   FISCAL YEAR 1995
   ----------------
   First Quarter.............................  $16 1/4   $11 1/2
   Second Quarter............................   20 1/4    14 3/4
   Third Quarter.............................   25 1/2    19
   Fourth Quarter............................   26 1/4    23 1/4
 
   FISCAL YEAR 1996
   ----------------
   First Quarter.............................   26 1/4    22 1/4
   Second Quarter............................   29 5/8    22 1/2
   Third Quarter.............................   39 1/2    27 1/2
   Fourth Quarter............................   38 3/4    32 1/2
 
   FISCAL YEAR 1997
   ----------------
   First Quarter.............................   37 1/4    30 3/4
   Second Quarter............................   55 7/8    31 1/2
   Third Quarter (through January 31, 1997)..   49 3/4    45
</TABLE>

     On January 31, 1997, the last sale price of the Common Stock as reported by
the Nasdaq National Market was $48 1/2.  As of January 31, 1997, the Company's
Common Stock was held by 167 stockholders of record.  The Company believes that
its Common Stock is beneficially held by at least 400 stockholders.

                                DIVIDEND POLICY

     The Company has never paid a cash dividend to the holders of its Common
Stock.  The Company intends to continue to retain earnings to finance its
business and, accordingly, does not currently anticipate paying cash dividends
to holders of its Common Stock.

                                       14
<PAGE>
 
                                 CAPITALIZATION

     The following table sets forth the capitalization of the Company at
December 31, 1996 and as adjusted to give effect to the receipt by the Company
of the anticipated net proceeds from the sale of the Debentures.

<TABLE>
<CAPTION>
                                                                                   DECEMBER 31, 1996
                                                                                 ----------------------
                                                                                  ACTUAL    AS ADJUSTED
                                                                                 ---------  -----------
                                                                                     (IN THOUSANDS)
<S>                                                                              <C>        <C>
Cash and marketable securities(1)..............................................  $171,551    $ 269,051
                                                                                 ========   ===========
Long-term debt:
 
   __% Convertible Subordinated Debentures due 2007............................        --      100,000
 
Stockholders' equity:
   Preferred stock, $.01 par value, 10,000,000 shares authorized; none issued..        --           --
   Common stock, $.01 par value, 50,000,000 shares authorized; 17,323,958
     shares issued and outstanding; _______ shares as adjusted(2)..............       226          226
   Additional paid-in capital..................................................   185,890      185,890
   Treasury Stock, at cost; 5,268,463 shares...................................   (38,287)     (38,287)
   Retained earnings...........................................................    35,672       35,672
                                                                                 --------    ----------
     Total stockholders' equity................................................   183,501      183,501
                                                                                 --------   -----------
       Total capitalization....................................................  $183,501   $  283,501
                                                                                 ========   ===========
 
- ----------------
</TABLE>
(1) Includes current cash balance as of December 31, 1996 and short-term
    marketable securities.

(2) Does not include at December 31, 1996 (i) an aggregate of 6,279,513 shares
    reserved for issuance pursuant to certain stock option agreements and stock
    option plans, (ii) 250,000 Shares reserved for issuance upon exercise of
    warrants issued in connection with the acquisition of Avicenna and (iii) ___
    shares reserved for issuance upon conversion of the Debentures.  See
    "Description of Debentures."

                                       15
<PAGE>
 
                                    BUSINESS
GENERAL

     Synetic, Inc. operates in two principal lines of business, plastics
technologies and healthcare communications.  Porex Technologies Corp. (together
with its subsidiaries, "Porex"), a wholly owned subsidiary of the Company,
designs, manufactures and distributes porous and solid plastic components and
products used in healthcare, industrial and consumer applications.  Porex's
principal products, which incorporate porous plastics, are used to filter, wick,
drain, vent or control the flow of fluids or gases.  Through its recently
acquired wholly owned subsidiary, Avicenna Systems Corporation, the Company has
directed its efforts in a new area of business relating to the use of Internet
technology to expand the channels of communication in the healthcare industry.
The creation of these new channels is intended to benefit providers and payors
of healthcare services by improving the quality of patient care, securing
appropriate utilization of healthcare services, reducing administrative costs
and enforcing benefit plan guidelines.

PLASTICS TECHNOLOGIES BUSINESS

   General

     Porex designs, manufactures and distributes porous and solid plastic
components and products used in healthcare, industrial and consumer
applications.  Porous plastics are permeable plastic structures having omni-
directional (i.e., porous in all directions to the flow of fluids or gases)
interconnecting pores.  Porous plastics are manufactured by Porex with pore
sizes between approximately 5 and 500 micrometers (one micrometer is equal to
one-millionth of a meter; an object of 40 micrometers in size is about as small
as can be discerned by the naked eye).  Porous plastic materials can be molded
from several thermoplastic raw materials and are produced by Porex at its own
manufacturing facilities as fabricated devices, custom-molded shapes, sheets,
tubes or rods depending on application or manufacturer specifications.  Porex
also purchases for resale through its distribution channels certain products
which are complementary to its manufactured product lines. As a result of the
Company's development activities, the Company anticipates future opportunities
in several areas of Porex's business, which may include drug-delivery systems,
personal care products and micro-electronics.

   Healthcare Products

     Porex's proprietary products for life sciences, clinical and surgical
applications include blood serum filters, blood tube closure devices, pipette
tips and a line of medical/surgical products designed primarily for use in
plastic and reconstructive surgery and maxillofacial surgery.  Porex also
manufactures and sells a line of plastic vials and produces components made to
the specifications of original equipment manufacturers for incorporation into
their healthcare products.

   Porex's blood serum filters are used to separate microscopic particles and
fibrous matter (fibrin) from centrifuged blood serum to prevent clogging of
automated laboratory chemical analysis equipment.  The filters allow the serum
to pass through while blocking passage of particulate materials.  Analysis of
the serum provides specific information as to a patient's health.  Porex also
manufactures a line of closure devices that are used with blood serum filters
and tubes.  In response to health concerns regarding the handling of human
blood, new blood testing equipment has been developed by other companies which
does not require filtered blood serum for analysis, or which eliminates the need
for handling of blood serum by medical personnel.  The use of such new equipment
has reduced the demand for Porex's current line of blood serum filters.

                                       16
<PAGE>
 
   Porex produces a line of filtered and non-filtered pipette tips which are
used for dispensing fluids, primarily in industrial research laboratories.

   Porex's surgical products are marketed primarily to surgeons who specialize
in plastic and reconstructive surgery and maxillofacial surgery.  The product
line includes MEDPOR(R) Surgical Implant material, which is polymeric
biomaterial used for craniofacial reconstruction and augmentation, and TLS(R)
Surgical Drainage Systems for small wound sites.  Porex also markets TLS(R)
Surgical Marker pens to mark the areas of proposed surgical incision.  Porex
manufactures MEDPOR(R) Surgical Implant material and distributes, and in some
cases assembles, the other items in its surgical product line.

   Porex manufactures various porous plastic components that it sells to other
healthcare product manufacturers for incorporation into their finished products.
These porous plastics are used to vent or diffuse gases or fluids and are used
as membrane supports in other manufacturers' products.  The components include
(i) disks used to support membranes, modules and other filtration devices, (ii)
a venting system for catheters which allows air to vent from a catheter as it is
inserted into a vein, while at the same time preventing blood spillage and
possible contamination of hospital personnel, (iii) a porous disk used in
pipette tips to prevent the fluid to be pipetted from passing into the pipette
instrument, and (iv) an oxygen diffuser, which is typically used in oxygen
therapy equipment to humidify oxygen.

   Porex manufactures and sells a full line of plastic vials for
pharmaceuticals.  Porex also produces close tolerance solid plastic components
which use most thermoplastic resins, but primarily polystyrene, polypropylene
and thermoplastic rubber for medical and industrial applications.  These
products are custom designed and produced to satisfy individual customer
specifications.

   Industrial Products

     Porex manufactures a variety of custom porous plastic components for
industrial applications.  These components are produced as molded shapes, and in
sheets, tubes and rods, individually designed to customer specifications as to
size, rigidity, porosity and other needs.

     Porex's industrial applications include (i) automotive products, primarily
porous plastic vents used in automobile batteries as a flame arrester, (ii)
wastewater treatment filter support media, (iii) filters to remove particulate
matter, oil and water residues from compressed air lines, (iv) silencers and
mufflers to reduce sound levels produced by compressed air exhaust, and (v)
products for facilitating the movement of powdered materials.  Porex also
manufactures a large variety of highly specialized plastic components to meet
specific applications for manufacturers.

   Consumer Products

     Porex manufactures a line of porous plastic components used in a variety of
home and office products and appliances.  Porex's consumer products include a
variety of writing pen tips or "nibs" which Porex supplies to manufacturers of
marking and highlighting pens.  The porous nib conducts the ink stored in the
pen barrel to the writing surface by capillary action.  Porex produces a variety
of porous plastic filters used in home water filters and conditioners.  The
filters are used for particle and sediment removal through devices attached to a
sink or faucet.  The Company also manufactures filters incorporating activated
carbon used to reduce chlorine levels in drinking water thereby improving its
taste and odor.  Porex's porous plastic components are used in health and beauty
aid products (such as deodorant and fragrance applicators).

                                       17
<PAGE>
 
HEALTHCARE COMMUNICATIONS BUSINESS

   Industry Background

     The U.S. healthcare industry continues to undergo rapid and dramatic
change. According to industry sources, current healthcare expenditures now
exceed $1 trillion and represent approximately 14% of gross domestic product.
The aging of the U.S. population should continue to fuel growth in aggregate
costs since older Americans consume more healthcare services.  Increasing
concern over the rising cost of healthcare in the United States has caused a
shift away from fee-for-service indemnity plans into health maintenance
organizations (HMOs) and other managed healthcare benefit plans.  This trend has
been accompanied by the emergence of various managed care techniques that such
organizations use to control costs.  These techniques include, but are not
limited to, negotiated price discounts with healthcare providers, restrictions
on physician access, increased emphasis on preventative healthcare services,
utilization review/case management functions, and shifting the economic risk for
the delivery of care to providers through alternative reimbursement models, such
as capitation and fixed fees.  Management believes that while these techniques
have initially been helpful in containing healthcare costs, managed care
organizations need an effective means of communicating with physicians and other
healthcare providers at the time of care delivery in order to further reduce
administrative and medical costs.  The fragmented healthcare information
infrastructure in place today makes it difficult for managed care organizations
to effectively communicate and implement benefit rules and care guidelines.

     Healthcare providers are also facing new pressures in this changing
practice environment.  Physicians in general have experienced declining incomes
and increased levels of financial risk due to the rise of managed care.  It is
management's belief that a physician's ability to absorb price decreases, comply
with plan guidelines and manage risk is frustrated by a lack of automation and
efficient communication in managed care processes and by payor fragmentation.
With approximately 80% of healthcare expenditures under physician control and a
significant portion of their time being spent on administrative tasks, an
effective channel of communication at the point of care should provide
measurable benefits to both payors and providers.  Management believes that
giving providers access to detailed clinical and administrative information in a
way that is easy to use, consistent among payors, and compatible with existing
information systems is critical to achieving further cost containment and
improved patient care.

     The growth of Internet technology has established the opportunity for a
low-cost solution to inter-enterprise connectivity while preserving investment
in legacy systems. Internet technology permits the integration of systems across
various healthcare constituencies regardless of differences in architectures,
platforms or operating systems. Technological improvements have converged with
changes in the healthcare industry in a way which enables new products and
services, that were previously not possible, to be offered.  See "Risk Factors-
- -Reliance on Rapidly Changing Technology."

     Business Strategy

     The Company's objective is to use Internet technology to create the most
influential interactive health services channel linking physicians with the
payors, suppliers and consumers of healthcare in order to control healthcare
costs and improve patient outcomes.  The Company expects to provide a content-
neutral, application rich utility thereby creating a channel which serves as a
conduit for the private content that any healthcare organization wishes to
communicate to physicians and other healthcare providers.  Key elements of the
Company's strategy are to:

 .  Accelerate the development of a low-cost service to provide a suite of
   communication, information and transaction functions by integrating the
   Avicenna and CareAgents acquisitions (see "Recent Transactions").  Avicenna
   develops and markets Intranets to managed care plans, hospitals and physician
   groups.  These Intranets provide organizations the ability to quickly link
   physicians, providers and suppliers to a vast array of public reference
   material, proprietary plans rules, treatment guidelines and managed care
   transactions.

                                       18
<PAGE>
 
   
 .  In addition, CareAgents had been developing complementary software focused
   on providing physicians, health plans and patients tools to conduct clincial
   commerce via the public Internet and private Intranets. Since these services
   will enable physicians and their offices to perform high volume, routine
   transactions in a uniform manner for all patients, it will help them practice
   medicine more effeciently in today's managed care environment.

 .  Differentiate this suite of client server applications by its ability to
   allow physicians and their staffs to conduct not only administrative but also
   clinical transactions. These transactions would include but not be limited to
   eligibility verification, referrals, treatment authorizations, claims and
   encounter submissions, as well as laboratory test submission and reporting,
   prescription writing, drug utilization and formulary review, and pharmacy
   routing. The ability to integrate payor-specific content such as benefit
   rules and care guidelines with patient-specific information at the time of
   treatment will significantly enhance the delivery of high quality, cost
   effective care.

 .  Contract with managed care organizations, integrated health delivery systems,
   pharmacy benefit managers and clinical laboratories so that they might
   provide physicians with access to their proprietary benefit plan information
   and treatment guidelines as well as their administrative and managed care
   processes.  Management believes that this new channel of communications will
   allow each of the parties to (i) leverage their existing healthcare
   information systems infrastructure, (ii) to integrate their proprietary rules
   and guidelines with transactions, and (iii) to realize administrative and
   medical resource savings while improving provider relationships and
   streamlining managed care processes.  The Company anticipates it will be
   compensated by such parties as a result of the value created.

     The Company is not aware of any business which currently provides the scope
and breadth of the services described above.  However, various companies
including, but not limited to, certain physician office management information
systems companies, EDI/data networking companies, online medical information
service companies, and systems integration companies, some of which may have
greater resources than the Company, have announced that they are developing a
combination of one or more of these products and services.  There can be no
assurance that such companies will not develop and successfully market the
healthcare communications products and services described herein in a manner
which would have a material adverse effect on the Company.  The Company's
management believes that its advantage lies in its prior experiences and
backgrounds in the healthcare industry which have resulted in a unique
understanding of the economics underlying the transaction capabilities it seeks
to provide.  Through direct experience, the Company's management also
understands the difficulties faced by healthcare payors and providers in
adopting and promoting a standard communication utility.  This knowledge base
combined with the technology resources described below in "Recent Acquisitions"
gives the Company a strong platform for executing its business strategy.

     Recent Acquisitions

     The Company recently completed two acquisitions in the healthcare
communications area. On December 24, 1996, the Company acquired Avicenna, a
privately held development stage company located in Cambridge, Massachusetts.
Avicenna's business plan has been to market and build Intranets for managed care
organizations, hospitals and physician groups. Avicenna's controlled access
Intranet systems are designed to allow payors and providers to exchange
transactional, procedural, patient outcomes and educational information. On
January 23, 1997, the Company acquired privately held CareAgents to add
management resources with expertise in large-scale commercial clinical
applications, medicine and information technology. CareAgents was an early
development stage company focussed on developing Internet clinical commerce
applications. The Company is presently integrating these acquisitions and
expects them to be the foundation on which its business strategy will be
developed. Avicenna and CareAgents have, collectively, approximately 50
employees.

     The Company acquired all of Avicenna's outstanding equity and indebtedness
(including stock options) for shares of Synetic Common Stock with a market value
of $30.5 million.  As additional consideration, the Company

                                       19
<PAGE>
 
issued to certain of the sellers nontransferable warrants covering 250,000
shares of Synetic Common Stock, exercisable after December 23, 1998 at a price
of $54.50 per share. Synetic acquired CareAgents for shares of Synetic Common
Stock with a market value of $5 million.

     During the quarter ended December 31, 1996, the Company recorded a non-
recurring charge of $28,600,000 relating to purchased research and development
costs in conjunction with its acquisition of Avicenna. Under generally accepted
accounting principles, the amount of purchase price allocable to purchased
research and development costs is required to be expensed immediately after the
acquisition. The Company expects to record a non-recurring charge in the quarter
ended March 31, l997 relating to purchased research and development costs in
conjunction with its acquisition of CareAgents in January, l997. While the exact
amount of the charge is not yet determinable, the Company does not expect this
charge to exceed $3 million.

     As a result of the acquisition of Avicenna and CareAgents, the Company
expects to incur significant research and development expenses and incur
additional operating losses in connection with this new area of business until
the products and services are successfully developed or marketed.  There can be
no assurances that the products or services will be successfully developed or
marketed.  The rate of aggregate expenditures at Avicenna and CareAgents
immediately prior to their acquisition was approximately $1,600,000 per quarter.
Research and development expenses may be materially greater in the future than
current amounts until the Company successfully develops its products and
services.  The Company, however, anticipates that such research and development
expenses will not exceed $2,500,000 per fiscal quarter for the third and fourth
quarters for the fiscal year ending June 30, 1997 and will not result in net
losses for the current fiscal year (excluding the non-recurring charges for
purchased research and development costs relating to the acquisition of Avicenna
and CareAgents) or for either of the fiscal quarters ending March 31, l997 or
June 30, l997.

     The Company is pursuing the development of its healthcare communications
business through the use of its internal resources as well as pursuing the
acquisition of complementary businesses.  The Company anticipates that it may
enter into acquisitions, joint ventures, strategic alliances or other business
combinations.  These transactions may materially change the nature and scope of
this business.  There can be no assurance that the Company will succeed in
consummating such transactions or that such transactions will ultimately provide
the Company with the ability to offer the products and services described.

ACQUISITION PROGRAM

     The Company maintains an acquisition program and intends to concentrate its
acquisition efforts in businesses which are complementary to the Company's
healthcare communications strategy.  This emphasis, however, is not intended to
limit in any manner the Company's ability to pursue acquisition opportunities in
other healthcare-related business or in other industries.  See "Risk Factors--
Acquisition Program" and "Business--Healthcare Communications Business--Recent
Acquisitions."

CERTAIN CORPORATE HISTORY

     Prior to June 28, 1989, the date of the initial public offering of the
Company, the Company was an indirect wholly owned subsidiary of Medco
Containment Services, Inc. ("Medco").  Thereafter, the Company became a publicly
held, partially owned subsidiary of Medco.  Medco provided healthcare cost
containment services, principally managed prescription drug programs, to benefit
plan sponsors.  On November 18, 1993, Medco was acquired by Merck & Co., Inc.
("Merck") in a merger transaction, and as a result, the Company became an
indirect, partially owned subsidiary of Merck.  Merck is a pharmaceutical
manufacturer.  Until December 14, 1994, the Company's operations consisted of
Porex and a group of subsidiaries that provided institutional pharmacy services
(the "Institutional Pharmacies Business").

                                       20
<PAGE>
 
     On December 14, 1994, the Company consummated certain transactions pursuant
to which:  (1) the Company sold the Institutional Pharmacies Business to
Pharmacy Corporation of America, an indirect wholly owned subsidiary of Beverly
Enterprises, Inc. (such sale is referred to herein as the "Divestiture"), for
approximately $107,300,000; (2) the Company purchased 5,268,463 shares of its
Common Stock from Merck for an aggregate purchase price of $37,764,019, pursuant
to the Purchase and Sale Agreement, dated as of May 24, 1994, between the
Company and Merck; and (3) SN Investors, a limited partnership the general
partner of which is SYNC, Inc. (the "General Partner"), whose sole stockholder
is Mr. Wygod, purchased 5,061,857 shares of Common Stock (the "Wygod Shares")
from Merck for an aggregate purchase price of $36,283,079, pursuant to an
assignment by the Company of the right to purchase such shares from Merck
contained in an Investment Agreement between Mr. Wygod, and the Company, dated
as of September 13, 1994 (the "Investment Agreement").  The Investment Agreement
also governs the terms and conditions under which the Wygod Shares will be held
by Mr. Wygod and his permitted assignees and transferees.  SN Investors has
agreed to be bound by all of the restrictions and obligations applicable to Mr.
Wygod under the Investment Agreement.  The purchases of shares of Common Stock
from Merck by the Company and SN Investors are hereinafter referred to as the
"Purchase."  As a result of the consummation of the Purchase, Mr. Wygod and SN
Investors own an aggregate of approximately 29.8% of the outstanding Common
Stock as of January 31, 1997 and Merck no longer owns an equity interest in the
Company.  The shares of Common Stock purchased by the Company are being held as
treasury shares and are no longer outstanding or entitled to vote.

     As more fully described in the 1996 10-K, the Investment Agreement provides
that, until the earliest to occur of December 14, 1998, the death or
adjudication of incompetency of Mr. Wygod or a Change of Control (as defined in
the Investment Agreement) (the "Restriction Period"), (a) Mr. Wygod and SN
Investors are required to vote (or cause to be voted) the Wygod Shares (i) with
respect to election of directors, for the nominees who would have been elected
based on the vote of all shares of Common Stock, other than the Wygod Shares, in
proportion to the votes that such nominees received, and (ii) on all other
matters to come before the stockholders of the Company, in the same manner as a
majority of the outstanding shares of Common Stock (other than the Wygod Shares)
are voted and (b) except for sales pursuant to a tender or exchange offer for
the shares of Common Stock that is not opposed by the Board of Directors of the
Company, neither Mr. Wygod nor SN Investors may transfer interests in the Wygod
Shares (except that Mr. Wygod may transfer interests in SN Investors to the
extent otherwise permitted by the Investment Agreement).  A "Change of Control"
under the Investment Agreement includes (A) various types of business
combination or other extraordinary transactions, (B) certain changes in the
composition of a majority of the Board of Directors of the Company and (C) the
issuance by the Company following the closing of the Purchase of shares of
Common Stock constituting in the aggregate more than 50% of the shares of Common
Stock outstanding as of immediately following the closing of the Purchase.  As
of January 31, 1997, the Company had issued 5,014,748 shares of Common Stock
since the closing of the Purchase.  Accordingly, the issuance of an aggregate of
1,241,002 additional shares of Common Stock would be a "Change of Control" as
described in clause (C) above.

                                       21
<PAGE>
 
                                   MANAGEMENT

DIRECTORS AND EXECUTIVE OFFICERS OF THE COMPANY

   The directors and executive officers of the Company are as follows:
<TABLE>
<CAPTION>
 
 
           NAME              AGE                         POSITION
           ----              ---                         --------                           
<S>                          <C>   <C>
James V. Manning...........    50  President and Chief Executive Officer; Director (4)
Inder-Jeet Gujral..........    38  Executive Vice President--President of Avicenna
David Margulies............    46  Executive Vice President--Chief Scientist
Ray E. Hannah..............    60  Vice President--PlasticTechnologies Group;
                                   Director[;President and Chief Executive Officer of Porex]
Victor L. Marrero..........    40  Vice President--Finance and Chief Financial Officer
Charles A. Mele............    40  Vice President--General Counsel; Director
Thomas R. Ferguson.........    69  Director(1)(2)(3)(4)
Mervyn L. Goldstein, M.D...    59  Director
Roger H. Licht.............    42  Director
Per G.H. Lofberg...........    49  Director
Herman Sarkowsky...........    71  Director(1)(2)(3)
Paul C. Suthern............    44  Director
Albert W. Weis.............    69  Director(1)(2)(3)(4)
Martin J. Wygod............    56  Chairman of the Board; Director
 
- -----------
</TABLE>
(1)  Member of the Audit Committee
(2)  Member of the Stock Option Committee
(3)  Member of the Compensation Committee
(4)  Member of the Executive Committee

     Pursuant to the terms of the Company's Certificate of Incorporation, the
Board of Directors is divided into three classes with staggered three-year
terms.  Not more than one class of directors is elected at any annual meeting of
stockholders.

     Messrs. Hannah, Licht, Lofberg and Sarkowsky have been elected for a term
expiring at the 1997 Annual Meeting.  Messrs. Manning, Mele and Weis have been
elected for a term expiring at the 1998 Annual Meeting.  Messrs. Ferguson,
Suthern, Wygod and Dr. Goldstein have been elected for a term expiring at the
1999 Annual Meeting.  See "Description of Capital Stock--Voting Rights."

     James V. Manning has been a director of the Company for more than five
years.  Mr. Manning has been Chief Executive Officer of the Company since
January 1995 and President of the Company since August 1996 and has been an
executive officer of the Company for more than five years.  Prior to December
1994, Mr. Manning

                                       22
<PAGE>
 
was an executive officer of Medco for more than five years.  He has also
been Chairman of the Board of COMNET Corporation ("Comnet"), a computer software
company, since 1993.

     Inder-Jeet Gujral has been Executive Vice President--President of Avicenna
of the Company since January 1997. Mr. Gujral was a founder of Avicenna. He was
a founder and principal of Lancet Technologies, Inc., a worldwide provider of
data management systems for hospital and healthcare-related agencies since 1988.
He earned a master's degree in business administration from Stanford University;
a master's degree in computer science from Rensselear Polytechnic Institute; and
a master's degree in physics from the Indian Institute of Technology, New Delhi,
India.

     Dr. David Margulies has been Executive Vice President--Chief Scientist of
the Company since January 1997. He was founder and president of CareAgents and
from 1990 to early 1996. Dr. Margulies was Executive Vice President and Chief
Scientist of the Cerner Corporation, a leading supplier of enterprise-level
clinical applications. Prior to such time, he was Vice President and Chief
Information Officer at Boston Children's Hospital and on the medical faculties
of the Harvard Medical College and Columbia College of Physicians and Surgeons.
He received his medical degree from Harvard Medical School.

     Ray E. Hannah has been a director of the Company for more than five years.
Mr. Hannah has been President of Porex since September 1987 and its Chief
Executive Officer since November 1992.  Mr. Hannah was the Chief Operating
Officer of Porex from November 1984 to November 1992.

     Victor L. Marrero has been Vice President--Finance and Chief Financial
Officer of the Company since December 1994 and has been an officer of the
Company for more than the last five years and was, until December 1994, an
officer of Medco for more than five years.

     Charles A. Mele has been a director of the Company for more than five
years.  Mr. Mele has been Vice President--General Counsel of the Company since
July 1995, was an executive officer of Medco for more than five years
until March 1995 and was an executive officer of the Company from May 1989 until
December 1994. Mr. Mele is also a director of Comnet and of Group 1 Software,
Inc., computer software companies.

     Thomas R. Ferguson has been a director of the Company for more than five
years.  He has been a member of the law firm of Ferguson, Case, Orr, Paterson &
Cunningham; for more than five years.

     Mervyn L. Goldstein, M.D. has been a director of the Company for more than
five years.  He has been a physician in private practice, Associate Clinical
Professor of Medicine at the Albert Einstein College of Medicine in New York
City and Attending Physician in Medicine and Oncology at Montefiore Medical
Center in New York City for more than five years.  Since December 1988 he has
been Physician Director of Quality Assurance at Montefiore Medical Center.

     Roger H. Licht has been a director of the Company for more than five years.
He has been a member of the law firm of Licht & Licht for more than five years.

     Per G.H. Lofberg has been a director of the Company since January 1995.
Mr. Lofberg has been President of the Merck--Medco Managed Care Division of
Merck since November 1993. Prior to that, Mr. Lofberg was Senior Executive Vice
President--Strategic Planning and Sales and Marketing of Medco for more than
five years.

     Herman Sarkowsky has been a director of the Company for more than five
years. He has been Chairman of the Board and Chief Executive Officer of
Sarkowsky Investment Corporation, a diversified investment company, for more
than five years. Mr. Sarkowsky is a director of Seafirst Bank, Eagle
Hardware & Garden Inc. and Hollywood Park, Inc.

                                       23
<PAGE>
 
     Paul C. Suthern has been a director of the Company since 1993.
Mr. Suthern has been Vice Chairman of the Company since July 1996 and was the
President and Chief Operating Officer of the Company from February 1993 until
July 1996 and was also the Chief Executive Officer from October 1993 until
January 1995.  Mr. Suthern was also the President and Chief Operating Officer of
Medco from November 1992 through December 1994 and Assistant to Medco's Chairman
from December 1991 to November 1992.  Prior thereto he was Executive Vice
President--Operations of Medco for more than five years.

     Albert M. Weis has been a director of the Company for more than five years.
He has been President of A.M. Weis & Co., Inc., a commodities trading
corporation, for more than five years.  Mr. Weis is a member of the Board of the
Commodities Clearing Corporation.

     Martin J. Wygod has been a director of the Company for more than five
years.  Mr. Wygod has been Chairman of the Board of the Company since May 1989.
From May 1989 to February 1993, Mr. Wygod also served as the Company's President
and Chief Executive Officer and until May 1994 was an executive officer of the
Company.  Until May 1994, Mr. Wygod was Chairman of the Board of Medco for more
than five years, and until January 1993 he also served as Chief Executive
Officer of Medco.  He is also engaged in the business of racing, boarding and
breeding thoroughbred horses and is President of River Edge Farm, Inc., which is
engaged in the business of breeding and boarding thoroughbred horses.

                                       24
<PAGE>
 
                           DESCRIPTION OF DEBENTURES


     The Debentures will be issued pursuant to an Indenture dated as of February
___, 1997 (the "Indenture"), a copy of which is filed as an exhibit to the
Registration Statement, between the Company and United States Trust Company of
New York, as trustee (the "Trustee").

     The terms of the Debentures include those stated in the Indenture and those
made part of the Indenture by reference to the Trust Indenture Act of 1939 (the
"Trust Indenture Act") as in effect on the date of the Indenture.  The
Debentures are subject to all such terms, and holders of the Debentures are
referred to the Indenture and the Trust Indenture Act for a statement thereof.
A copy of the Form of Indenture is filed an exhibit to the Registration
Statement of which this Prospectus is a part.  The following summary of certain
provisions of the Indenture does not purport to be complete and is qualified in
its entirety by reference to the Indenture, including the definition therein of
certain terms used below.  As used in the "Description of Debentures" references
to "the Company" refer to Synetic, Inc. and not to any of its subsidiaries.

GENERAL

     The Debentures will be general unsecured obligations of the Company,
subordinate in right of payment to certain other obligations of the Company, and
convertible at any time prior to maturity unless previously redeemed or
repurchased into Common Stock of the Company as described below. The Debentures
will be limited to $100,000,000 aggregate principal amount at maturity
($115,000,000 aggregate principal amount at maturity if the Underwriter's over-
allotment option is exercised in full). The Debentures will bear interest from
the date of initial issuance, 1997, at the rate per annum shown on the cover
page of this Prospectus, payable semiannually on August 15 and February 15 in
each year to holders of record of Debentures at the close of business on the
August 1 or February 1 next preceding the interest payment date. The first
interest payment date will be August 15, 1997. Interest will be computed on the
basis of a 360-day year of twelve 30-day months. The Debentures will mature on
February 15, 2007, and will be issued in denominations of $1,000 and integral
multiples thereof and will be issued only in fully registered form.

     Prior to the offering of the Debentures, there has been no public trading
market for the Debentures.  Although the Company intends to make application to
list the Debentures on the Nasdaq National Market, there can be no assurance
that an active public market for the Debentures will develop or, if a public
market develops, that the market price will exceed the public offering price set
forth on the covering page of this Prospectus.  If an active public
trading market for the Debentures does not develop, the market prices and
liquidity of the Debentures may be adversely affected.  Because the Debentures
are convertible into Common Stock, the prices at which the Debentures trade in
the market will likely be affected by the price of the Company's Common Stock.

     Principal and interest on the Debentures are to be payable at the offices
of the Company or its agent maintained for such purposes; provided that the
payment of interest may, at the option of the Company, be made by check mailed
to a holder at his registered address.  The Debentures will be convertible at
the aforesaid offices of the Company or its agent.

CONVERSION OF DEBENTURES

     The holder of any Debenture will be entitled at any time prior to the close
of business on February 15, 2007, subject to prior redemption or repurchase, to
convert such Debenture (or portions thereof which are in denominations of $1,000
or integral multiples thereof) at the principal amount thereof, into shares of
Common Stock, at the conversion price set forth on the cover page of this
Prospectus, subject to adjustment as described below.  Interest will be paid on
any semiannual interest payment date with respect to Debentures surrendered for
conversion after the record date for the payment of interest to the registered
holder on such record date.  Debentures

                                       25
<PAGE>
 
surrendered for conversion after a record date but prior to the next succeeding
interest payment date must be accompanied by payment of an amount equal to the
interest thereon which is to be paid on such interest payment date.  No payment
or adjustment will be made on conversion of any Debenture for interest accrued
thereon or dividends on any Common Stock issued.  The Company is not required to
issue fractional shares of Common Stock upon conversion of Debentures, and, in
lieu thereof, will pay a cash adjustment based upon the market price of the
Common Stock on the last Trading Day (as defined in the Indenture) prior to the
date of conversion.  In the case of Debentures called for redemption, conversion
rights will expire at the close of business on the business day prior to the
redemption date.

     The initial conversion price is subject to adjustment as set forth in the
Indenture in certain events, including: (i) the issuance of stock of the Company
as a dividend or distribution on the Common Stock; (ii) certain subdivisions,
combinations, and reclassification of the Common Stock; (iii) the issuance to
all holders of Common Stock of certain rights or warrants entitling them to
subscribe for Common Stock at less than the current market price (as defined);
(iv) the distribution to all holders of Common Stock of assets or debt
securities of the Company or rights or warrants (other than as referred to
above) to purchase assets, debt securities or other securities of the Company
(excluding cash dividends or distributions from current or retained earnings);
(v) the issuance, in certain circumstances, of shares of Common Stock for
consideration less than the then current market price and conversion price; and
(vi) the issuance, in certain circumstances, of securities convertible into or
exchangeable for shares of Common Stock (other than pursuant to transactions
described above) for a consideration per share of Common Stock deliverable on
such conversion or exchange that is less than the then current market price and
conversion price of the Common Stock on the date of issuance of such security.
As used above, the "current market price" per share of Common Stock is the lower
of (x) the average of the last reported sales prices of the Common Stock (as
reported by the Nasdaq National Market) for 15 consecutive trading days
commencing 25 trading days before the date in question or (y) the last reported
sales price at the most recent close of trading prior to the time in question
(except that, in the case of an issuance of rights or warrants or a distribution
of assets or securities to holders of Common Stock, clause (y) will not apply).
No adjustment in the conversion price will be required unless such adjustment
would require a change of at least 1% in the price then in effect; but any
adjustment that would otherwise be required to be made shall be carried forward
and taken into account in any subsequent adjustment. The Company may at any time
reduce the conversion price by any amount for any period of time, provided that
the conversion price is not less than the par value of a share of Common Stock,
the period during which the reduced price is in effect is at least 20 days or
such longer period as may be required by law and the reduced price is
irrevocable during such period.

     If the Company consolidates or mergers into or sells, leases, conveys or
otherwise disposes of all or substantially all of its assets to any person, as a
result of which holders of Common Stock shall be entitled to receive stock,
other securities, other property or assets (including cash) with respect to or
in exchange for such Common Stock, the Debentures will become convertible only
into the kind and amount of securities, cash or other assets which the holders
of the Debentures would have owned immediately after the transaction if the
holders had converted the Debentures immediately before the effective date of
the transaction at the conversion price in effect immediately prior to such
effective date.

     If at any time the Company makes a distribution of property to its
stockholders which would be taxable to such stockholders as a dividend for
federal income tax purposes (e.g., distributions of evidences of indebtedness or
assets of the Company, but generally not stock dividends) and, pursuant to the
anti-dilution provisions of the Indenture, the conversion price of the
Debentures is reduced, such reduction may be deemed to be the receipt of taxable
income by the holders of Debentures.

     OPTIONAL REDEMPTION OF DEBENTURES

     The Debentures will be redeemable, at the option of the Company, in whole
at any time or in part from time to time, on or after February 15, 2000, at the
redemption prices (expressed as percentages of the principal

                                       26
<PAGE>
 
amount) set forth below plus accrued and unpaid interest to the redemption date,
if redeemed during the 12-month period beginning February 15 of the years
indicated below: 

 
           YEAR                                 PERCENTAGE
           ----                                 ---------- 
 
           ____..............................      ___%
           ____..............................      ___%
           ____..............................      ___%
           ____..............................      ___%
           ____ and thereafter...............      100%
 

     In the event of redemption of less than all of the Debentures, the
Debentures will be chosen for redemption by the Trustee as provided in the
Indenture, but generally pro rata or by lot.  Notice of redemption will be
mailed at least 15 days but not more than 60 days before the redemption date to
each holder of Debentures to be redeemed at its registered address.  On and
after the redemption date interest ceases to accrue on Debentures or portions
thereof called for redemption.

REPURCHASE AT OPTION OF HOLDER UPON OCCURRENCE OF A DESIGNATED EVENT

     If at any time there occurs any Designated Event (as defined below) with
respect to the Company, each holder of Debentures shall have the right, at the
holder's option, to require the Company to repurchase all such holder's
Debentures, or a portion thereof which is $1,000 or any integral multiple
thereof, promptly following the 30th day after the date of the Company Notice
(as defined below), at 100% of their principal amount, together with accrued and
unpaid interest to the date fixed for repurchase.

     Within 15 days after the occurrence of a Designated Event, the Company is
obligated to mail to holders of record of the Debentures a notice (the
"Company Notice") of the occurrence of such Designated Event and of the
repurchase right arising as a result thereof.  The Company shall deliver a copy
of the Company Notice to the Trustee and shall cause a copy of such notice to be
published in a newspaper of general circulation in the Borough of Manhattan, The
City of New York.  To exercise the repurchase right, holders of Debentures must
deliver on or before the 30th day after the date of the Company Notice
irrevocable written notice to the Company (or an agent designated by the Company
for such purpose) of the holder's exercise of such right, together with the
Debentures with respect to which the right is being exercised, duly authorized
for transfer.

     A Designated Event shall be deemed to have occurred, subject to the
provisions below, upon the consummation of a purchase, merger, acquisition,
transfer or other transaction involving a "Change in Control".  As used herein,
a "Change in Control" of the Company shall be deemed to have occurred at such
time as any person, together with such person's "affiliates" or "associates" (as
such terms are defined in Rule 12b-2 under the Exchange Act, as in effect on the
date of the Indenture), other than a Permitted Holder (collectively, an
"Acquiring Person"), first is or becomes the "beneficial owner" (as such term is
defined in Rule 13d-3 under the Exchange Act, as in effect on the date of the
Indenture), directly or indirectly, through such purchase, merger, acquisition,
transfer or other transaction, of shares of capital stock of the Company
entitling the Acquiring Person to exercise more than 50% of the total voting
power of all shares of capital stock of the Company entitled to vote in
elections of directors.

                                       27
<PAGE>
 
     A "Permitted Holder" will be defined to mean Martin J. Wygod, his family 
members, any of their spouses and any Person controlled, directly or indirectly,
or beneficially owned by Martin J. Wygod or such family members or spouses and, 
upon the death of Martin J. Wygod, shall also include any executors, 
administrators, testamentary trustees, heirs, legatees or beneficiaries of 
Martin J. Wygod and any Person controlled, directly or indirectly, or 
beneficially owned by any such executors, administrators, testamentary trustees,
heirs, legatees or beneficiaries.

     Notwithstanding the foregoing, a Designated Event shall be deemed not to
have occurred (i) if the last sale price of the Common Stock for any five
trading days during the ten trading days immediately preceding the Change in
Control is at least equal to 105% of the conversion price in effect immediately
preceding the Change in Control or (ii) if at least 80% of the consideration
(excluding cash payments for fractional shares or cash payments for appraisal
rights) in the transaction or transactions constituting the Change in Control
consists of shares of common stock or securities convertible into common stock
that are, or upon issuance will be, traded on a national securities exchange or
through the NASDAQ National Market System and the consolidated net worth of the
surviving entity (or the entity issuing common stock or securities convertible
into shares of common stock in such transaction or transactions, if such entity
guarantees the Company's obligations under the Debentures) immediately after
such transaction or transactions, as measured according to generally accepted
accounting principles as in effect on the date hereof, is equal to or greater
than the consolidated net worth of the Company immediately preceding the Change
in Control or (iii) if, in the case of an acquisition by the Company or a
subsidiary of the Company of a business for consideration consisting of or
including shares of Common Stock and/or securities convertible into Common
Stock, the terms of such acquisition provide that, (I) from and after the
consummation of such acquisition and until at least the earlier of (x) two years
from the date of such acquisition or (y) the date on which the Acquiring Person
transfers substantially all of such shares of Common Stock and/or convertible
securities, the Acquiring Person will cause the shares of capital stock of the
Company owned by it at the time of any stockholder vote or action by consent for
the election of directors of the Company to be voted in favor of the election,
as a majority of the members of the Board of Directors of the Company, of
persons who were directors or executive officers of the Company immediately
prior to entry into the agreement or agreements pursuant to which the
transaction or transactions were consummated ("Pre-Acquisition Managers"),
provided that at least a majority of the Pre-Acquisition Managers so elected
were directors or executive officers of the Company for at least twelve months
immediately prior to entry into such agreement or agreements, and (II) the
Acquiring Person will not, for a period of two years from the consummation of
the acquisition, permit persons designated by it to become a majority of the
members of the Board of Directors of the Company. As used in the first sentence
of the preceding paragraph, the term "transfer" shall include, without
limitation, a transfer of the type referred to in clause (iii)(I)(y) of the
preceding sentence but shall exclude a transfer referred to in such clause
(iii)(I)(y) as to any transferee who agrees to be bound by the agreements of the
Acquiring Person described in clause (iii) of the preceding sentence for the
remainder of the two-year period referred to therein.

SUBORDINATION

     The indebtedness evidenced by the Debentures will be subordinated to the
prior payment when due of the principal of, premium, if any, and interest on all
present and future Senior Debt (as defined below). Upon maturity of any Senior
Debt, payment in full must be made on such Senior Debt before any payment of the
principal of, or interest on, the Debentures is made. During the continuance of
any default in payment of principal or premium, if any, or interest on Senior
Debt (a "Payment Default"), no payment of the principal of, or interest on, the
Debentures may be made by the Company unless and until such default is cured or
waived. Upon any distribution of assets of the Company in any dissolution,
winding-up, liquidation or reorganization of the Company, payment of the
principal of, and interest on, the Debentures will be subordinated, to the
extent and in the manner set forth in the Indenture, to the prior payment in
full of all Senior Debt. Such subordination will not prevent the occurrence of
any Event of Default (as defined in the Indenture).

     "Senior Debt" means (a) the principal of, premium, if any, and interest on
all Debt (other than the Debentures), whether outstanding on the date of the
Indenture as originally executed or thereafter created or incurred, unless, in
the agreement or instrument creating or evidencing the same or pursuant to which
the same is outstanding, it is provided that such Debt is not superior in right
of payment to the Debentures, and (b) any amendment, modification, deferral,
renewal, refunding or extension of any such Senior Debt, or debentures, notes or
other evidences of indebtedness issued in exchange for any such Senior Debt.
"Debt" means (a) all indebtedness of the Company for borrowed money, (b) all
indebtedness of the Company which is evidenced by a

                                       28
<PAGE>
 
note, debenture, bond or other similar instrument (including capitalized lease
and purchase money obligations) and (c) all indebtedness of the Company
(including capitalized lease obligations) incurred, assumed or given in the
acquisition (whether by way of purchase, merger or otherwise) of any business,
real property or other assets, except assets acquired in the ordinary course of
the acquiror's business; any indebtedness of others described in the preceding
clauses (a), (b) and (c) which the Company has guaranteed or for which it is
otherwise liable; and any amendment, renewal, extension or refunding of any such
indebtedness. Notwithstanding the foregoing, Senior Debt shall not include (A)
indebtedness evidenced by the Debentures, (B) indebtedness of the Company that
is expressly subordinated in right of payment to the Debentures and (C)
indebtedness of the Company to an affiliate or a subsidiary of the Company.

     The Debentures are obligations exclusively of the Company.  Since the
operations of the Company are currently conducted through subsidiaries, the cash
flow of the Company and the consequent ability to service debt of the Company,
including the Debentures, are dependent[, in part,] upon the earnings of its
subsidiaries (and the distribution of those earnings to the Company or upon
loans or other payments of funds by those subsidiaries to the Company).  The
subsidiaries are separate and distinct legal entities and have no obligation,
contingent or otherwise, to pay any amounts due pursuant to the Debentures or to
make any funds available therefor, whether in dividends, loans or other
payments.  In addition, the payment of dividends and the making of loans and
advances to the Company by its subsidiaries may be subject to statutory or
contractual restrictions, are contingent upon the earnings of those subsidiaries
and are subject to various business considerations.

     The Debentures will be effectively subordinated to all indebtedness and
other liabilities, including current liabilities and commitments under leases,
if any, of the Company's subsidiaries.  Any right of the Company to receive
assets of its subsidiaries upon liquidation or reorganization of the
subsidiaries (and the consequent right of the holders of the Debentures to
participate in those assets) will be effectively subordinated to the claims of
the subsidiaries' creditors (including the subsidiaries' trade creditors),
except to the extent that the Company is itself recognized as a creditor of the
subsidiaries, in which case the claims of the Company would still be
subordinated to any security interests in the assets of such subsidiaries and
any indebtedness of such subsidiaries senior to that held by the Company.

     As of the date of this Prospectus, the Company had no Senior Debt
outstanding and the Company's subsidiaries had no indebtedness for borrowed
money.  The Indenture will not restrict the incurrence of Senior Debt or other
indebtedness, secured or unsecured, by the Company or any subsidiary.

MERGER, CONSOLIDATION OR SALE OF ASSETS

     The Company may not consolidate or merge with or into, or sell, lease,
convey or otherwise dispose of all or substantially all of its assets to,
another corporation, person or entity unless (i) the Company is the surviving
person or the successor or transferee is a corporation organized under the laws
of the United States, any state thereof or the District of Columbia, or a
corporation or comparable legal entity organized under the laws of a foreign
jurisdiction and whose equity securities are listed on a national securities
exchange in the United States or authorized for quotation on the Nasdaq National
Market (provided, however, that in the case of a transaction where the surviving
entity is organized under the laws of a foreign jurisdiction, the Company may
not consummate the transaction without first making provision for the
satisfaction of its obligations to repurchase Debentures following a Designated
Event, if any), (ii) the successor assumes all the obligations of the Company
under the Debentures and the Indenture and (iii) after such transaction no Event
of Default exists.

COVENANTS

     The Company shall not adopt any plan of liquidation (other than a plan of
liquidation incident to a permitted merger, consolidation, sale of assets or
other transaction described in the preceding paragraph) which provides for,

                                       29
<PAGE>
 
contemplates or the effectuation of which is preceded by, (i) the sale, lease,
conveyance or other disposition of all or substantially all of the assets of the
Company otherwise than substantially as an entirety and (ii) the distribution of
all the proceeds of such sale, lease, conveyance or other disposition unless the
Company makes provisions for satisfaction of the Company's obligation to pay
principal and interest on the Debentures.

EVENTS OF DEFAULT AND REMEDIES

     An Event of Default is: default for 30 days in payment of interest on the
Debentures; default in payment when due of principal and premium, if any;
failure by the Company for 30 days after notice to comply with any of its other
agreements in the Indenture or the Debentures, or in the case of failure by the
Company to comply with the restrictions on liquidation and on consolidation,
merger or transfer or lease of substantially all of its assets or the provisions
regarding the conversion of Debentures, with such notice but without such
passage of time; default by the Company or a Significant Subsidiary (as defined
below) under and acceleration prior to maturity of, or the failure to pay at
maturity, certain other indebtedness of the Company or a Significant Subsidiary
for money borrowed aggregating in excess of $10,000,000 and continuance of such
default for 30 days after notice; failure by the Company or a Significant
Subsidiary to pay certain final judgments aggregating in excess of $5,000,000
(excluding amounts covered by insurance as to which the insurer has not denied
liability); and certain events of bankruptcy or insolvency.  "Significant
Subsidiary" means a "significant subsidiary" as defined in Rule 1-02 of
Regulation S-X under the Securities Act and the Exchange Act (as such Regulation
is in effect on the date of issuance of the Debentures).

     If any Event of Default occurs and is continuing, the Trustee or the
holders of at least 25% in principal amount of the then outstanding Debentures
may declare all the Debentures to be due and payable immediately; except that in
the case of an Event of Default arising from certain events of bankruptcy or
insolvency, all outstanding Debentures become due and payable without any action
or notice by the Trustee or any holder.  Holders of the Debentures may not
enforce the Indenture or the Debentures except as provided in the Indenture.
Subject to certain limitations, holders of a majority in principal amount of the
then outstanding Debentures may direct the Trustee in its exercise of any trust
or power.  The Trustee may withhold from holders of the Debentures notice of any
continuing Default or Event of Default (except a Default or Event of Default in
payment of principal or interest) if it determines that withholding notice is in
their interest.

     The holders of a majority in aggregate principal amount of the Debentures
then outstanding may on behalf of the holders of all of the Debentures waive any
past Default or Event of Default under the Indenture and its consequences except
a Default in the payment of interest on, or the principal of, the Debentures or
a Default or an Event of Default arising with respect to the conversion rights
of holders.

     The Company is required to deliver to the Trustee annually a statement
regarding compliance with the Indenture, and upon becoming aware of any Default
or Event of Default, a statement specifying such Default or Event of Default.

     A director, officer, employee or stockholder, as such, of the Company shall
not have any liability for any obligations of the Company under the Debentures
or the Indenture or for any claim based on, in respect of, or by reason of, such
obligations or their creation.  Each holder of the Debentures by accepting a
Debenture waives and releases all such liability.  The waiver and release are
part of the consideration for issuance of the Debentures.

SATISFACTION AND DISCHARGE OF THE INDENTURE

     The Company may terminate its obligations under the Indenture at any time
by delivering all outstanding Debentures to the Trustee for cancellation.  After
all the Debentures have been called for redemption, the Company may terminate
all of its obligations under the Indenture, other than its obligations to pay
the principal of and interest on the Debentures and certain other obligations,
at any time, by depositing with the Trustee money or non-callable U.S.
Government obligations sufficient to pay all remaining indebtedness on the
Debentures.

                                       30
<PAGE>
 
AMENDMENT, SUPPLEMENT AND WAIVER

     Subject to certain exceptions, the Indenture or the Debentures may be
amended or supplemented with the consent of the holders of at least a majority
in principal amount of such then outstanding Debentures, and any existing
default or compliance with any provision may be waived with the consent of the
holders of a majority in principal amount of the then outstanding Debentures.
Without the consent of any holder of the Debentures, the Company and the Trustee
may amend or supplement the Indenture or the Debentures to cure any ambiguity,
defect or inconsistency, to provide for uncertificated Debentures in addition to
or in place of certificated Debentures, to provide for the assumption of the
Company's obligations to holders of the Debentures in the case of a merger or
acquisition, or to make any change that does not materially adversely affect the
legal rights of any holder of the Debentures.  Without the consent of each
holder affected, the Company may not reduce the principal amount of Debentures
the holders of which must consent to an amendment of the Indenture; reduce the
rate or change the interest payment time of any Debenture; reduce the principal
of or change the fixed maturity of any Debenture or alter the redemption
provision with respect thereto; make any Debenture payable in money other than
that stated in the Debenture; make any change in the provisions concerning
waiver of Defaults or Events of Default by holders of the Debentures or rights
of holders to receive payment of principal or interest; make any change that
adversely affects the right to convert any Debenture; or make any change in the
subordination provisions that adversely affects the rights of any holder.

CONCERNING THE TRUSTEE

     United States Trust Company of New York will be Trustee under the
Indenture.  The Trustee has certain banking relationships with the Company.

     The Indenture contains certain limitations on the rights of the Trustee,
should it become a creditor of the Company, to obtain payment of claims in
certain cases, or to realize on certain property received in respect of any such
claim as security or otherwise.  The Trustee will be permitted to engage in
other transactions; however, if it acquires any conflicting interest (as
defined), it must eliminate such conflict or resign.

     The holders of a majority in principal amount of the then outstanding
Debentures will have the right to direct the time, method and place of
conducting any proceeding for exercising any remedy available to the Trustee.
The Indenture provides that in case an Event of Default shall occur (which shall
not be cured), the Trustee will be required, in the exercise of its power, to
use the degree of care of a prudent man in the conduct of his own affairs.
Subject to such provisions, the Trustee will be under no obligation to exercise
any of its rights or powers under the Indenture at the request of any of the
holders of the Debentures, unless they shall have offered to the Trustee
security and indemnity satisfactory to it.

REPORTS TO DEBENTUREHOLDERS

     The Company intends to furnish to holders of the Debentures all quarterly
and annual reports which it furnishes to holders of its Common Stock.

                                       31
<PAGE>
 
                          DESCRIPTION OF CAPITAL STOCK

     The following description of the capital stock of the Company is subject to
the Delaware General Corporation Law and to provisions contained in the
Company's Certificate of Incorporation and By-Laws, copies of which are exhibits
to the 1996 10-K that is incorporated by reference into this Prospectus.
Reference is made to such exhibits for a detailed description of the provisions
thereof summarized below.

     The authorized capital stock of the Company consists of 10,000,000 shares
of Preferred Stock, $.01 par value (the "Preferred Stock"), and 50,000,000
shares of Common Stock, $.01 par value.  None of the Preferred Stock is issued
and outstanding.  At January 31, 1997, there were 17,526,247 shares of Common
Stock outstanding.  Holders of capital stock of the Company have no preemptive
or other subscription rights.

PREFERRED STOCK

     The Preferred Stock may be issued from time to time in one or more series,
without stockholder approval.  The Board of Directors is authorized to determine
(subject to limitations prescribed by law) the other rights including voting
rights, if any, preferences, terms and limitations to be granted to and imposed
upon any wholly unissued series of Preferred Stock and to fix the number of
shares of any series of Preferred Stock and the designation of any such series.
The Company has no present plans to issue any shares of Preferred Stock.
Because of its broad discretion with respect to the creation and issuance of any
series of Preferred Stock without stockholder approval, the Board of Directors
could adversely affect the voting power of Common Stock.  The issuance of
Preferred Stock may have the effect of delaying, deferring or preventing a
change in control of the Company.

COMMON STOCK

     Subject to prior rights of any Preferred Stock then outstanding, the
holders of outstanding shares of Common Stock are entitled to receive dividends
out of assets legally available therefor declared and paid by the Company.  The
Company does not currently anticipate paying cash dividends to holders of its
Common Stock.

     Upon liquidation, dissolution or winding up of the Company, the assets
legally available for distribution to stockholders are distributable ratably
among the holders of the Common Stock at the time outstanding, subject to the
rights, if any, of the holders of any Preferred Stock then outstanding.  Since
the Company's Board of Directors has the authority to fix the rights and
preferences of, and to issue, the Company's authorized but unissued Preferred
Stock without approval of the holders of its Common Stock, the rights of such
holders may be materially limited or qualified by the issuance of the Preferred
Stock.

Voting Rights

     Stockholders are entitled to one vote for each share of Common Stock held
of record, except that for the election of directors, stockholders have
cumulative voting rights.  Cumulative voting for directors means that, at each
election of directors, the number of shares eligible to be voted by a
stockholder is multiplied by the number of directors to be elected.  A
stockholder may cast all such stockholder's votes for a single candidate, or may
allocate them among two or more candidates in any manner such stockholder
chooses.  For example, if three directors are to be elected, holders of one-
third of the shares would be able, by cumulating their votes, to elect one
director, regardless of how the other shares are voted.  Currently, the Company
has 11 directors.  The maximum number of directors permitted under the Company's
Certificate of Incorporation is 12. The Company expects to propose to its
stockholders to expand the number of permitted directors at its next annual
meeting of stockholders.

     The affirmative vote of the holders of at least two-thirds of the Company's
shares entitled to vote in an election of directors is required to amend (i) the
provisions of the Company's Certificate of Incorporation relating to cumulative
voting, classification of the Company's directors into three classes, election
of only one-third of the Board at each annual meeting of stockholders and the
power to remove directors or fill vacancies, and (ii) the By-

                                       32
<PAGE>
 
Laws to increase the number of directors above 12.  The Company's Certificate of
Incorporation also provides that any or all directors may be removed with or
without cause prior to completion of their term only upon the vote of holders of
two-thirds of the outstanding shares of Common Stock entitled to vote generally
in the election of directors.

     The provisions in the Certificate of Incorporation of the Company relating
to a staggered Board of Directors, super-majority requirements and delegation of
rights to issue Preferred Stock may have the effect not only of discouraging
tender offers or other stock acquisitions but also of deterring existing
stockholders from making management changes.  A staggered Board, while promoting
stability in Board membership and management, also moderates the pace of any
change in control of the Board of Directors by extending the time required to
elect a majority, effectively requiring action in at least two annual meetings.
Moreover, a staggered Board makes it more difficult for minority stockholders,
even with cumulative voting, to elect a director.  For example, to elect one
director of a non-staggered 12-member Board, stockholders with cumulative voting
would need only one-twelfth of the votes cast.  To elect one member of a
staggered Board with three classes and 12 members, stockholders with cumulative
voting would need one-fourth of the votes cast.  The provisions with respect to
removal of directors, while intended to prevent circumvention of benefits
derived from classification of directors and to prevent a transfer of control of
the Board of Directors through the removal process, also have the effect of
preventing removal of a director for just cause by a majority of outstanding
voting shares.  The ability of the Board of Directors to issue Preferred Stock,
while providing flexibility in connection with possible acquisitions and other
corporate purposes, could make it more difficult for a third party to secure a
majority of outstanding voting stock.  See "Risk Factors--Certain Antitakeover
Effects."  In addition, for a description of voting restrictions on shares held
by SN Investors, see "Business--Certain Corporate History" contained elsewhere
in this Prospectus and "Certain Relationships and Related Transactions" in the
1996 10-K.

Transfer Agent and Registrar

     The transfer agent and registrar for the Common Stock is Registrar &
Transfer Company.

                        SHARES ELIGIBLE FOR FUTURE SALE

     As of January 31, 1997, the Company has 17,526,247 shares of Common Stock
outstanding.  The 5,061,857 Wygod Shares (as defined in "Business--Certain
Corporate History") are "restricted securities" within the meaning of Rule 144,
subject to the volume restrictions of Rule 144 but for which the two-year
holding period has expired.  Additionally, 45,390 shares issued in connection
with the Avicenna Acquisition and all 106,209 shares issued in connection with
the acquisition of CareAgents are subject to a two year lock-up.  In the
Avicenna Acquisition, certain employees of Avicenna received options to purchase
161,015 shares of Common Stock, 80,522 of which vested on December 24, 1996 and
80,493 of which will vest on December 24, 1998.  As additional consideration in
the Avicenna Acquisition, certain selling stockholders also received, in the
aggregate, nontransferable warrants covering 250,000 shares of Common Stock,
which are exercisable after December 23, 1998.

     Of the outstanding shares as of January 31, 1997, 12,312,791 shares not
owned by SN Investors are freely tradable without restrictions or further
registration under the Securities Act; provided, however, that any shares owned
by an "affiliate" of the Company (as that term is defined in the rules and
regulations under the Securities Act) may not be resold in a public distribution
except in compliance with the registration requirements of the Securities Act or
pursuant to Rule 144 thereunder.  In general, Rule 144 under the Securities Act
provides that an affiliate of the Company or any holder of restricted
securities, subject to any applicable holding period, may sell within any three-
month period a number of shares that does not exceed the greater of 1% of the
then outstanding shares of the Common Stock or the average weekly trading volume
in composite trading on all exchanges during the four calendar weeks preceding
such sale.  In addition, sales under Rule 144 may be made only through
unsolicited "broker's transactions" and are subject to various other conditions.

                                       33
<PAGE>
 
     As more fully set forth in "Certain Relationships and Related Transactions"
in the 1996 10-K, the Wygod Shares are subject to certain contractual
restrictions on transfer.  Upon expiration of such restrictions, SN Investors
may be able to sell without registration under the Securities Act the number of
such shares permitted under Rule 144, in a transaction complying with the
registration requirements of the Securities Act or in a private transaction not
subject to such requirements.  The Investment Agreement (as more fully described
in "Certain Relationships and Related Transactions" in the 1996 10-K), provides
certain demand registration rights to Mr. Wygod at Mr. Wygod's expense, which
are assignable to any permitted transferee of the Wygod Shares; provided that in
no event is the Company required to file in the aggregate more than two
registration statements in connection therewith.  Mr. Wygod has not assigned
such registration rights to SN Investors.  While Mr. Wygod currently intends to
assign such registration rights to SN Investors in the event the General Partner
determines to sell or otherwise transfer the Wygod Shares under circumstances in
which registration would be required, Mr. Wygod is under no obligation to do so.

     For information concerning shares which may be issued under the Company's
stock option plans, see "Risk Factors--Shares Available for Future Sale."

                                       34
<PAGE>
 
                                  UNDERWRITING

     Subject to the terms and conditions set forth in a purchase agreement (the
"Purchase Agreement") between the Company and Merrill Lynch, Pierce, Fenner &
Smith Incorporated (the "Underwriter"), the Company has agreed to sell to the
Underwriter, and the Underwriter has agreed to purchase from the Company, the
entire principal amount of the Debentures.  The Purchase Agreement provides that
the obligations of the Underwriter are subject to certain conditions precedent
set forth in the Purchase Agreement and that the Underwriter will be obligated
to purchase all of the principal amount of Debentures offered hereby if any of
such Debentures are purchased.

     The Underwriter has advised the Company that it proposes initially to offer
the Debentures to the public at the public offering price set forth on the cover
page of this Prospectus, and to certain dealers at such price less a concession
not in excess of ____% of the principal amount thereof.  The Underwriter may
allow, and such dealers may reallow, a discount not in excess of ___% of the
principal amount thereof to certain other dealers.  After the offering
contemplated hereby, the offering price, concession and discount may be changed.

     The Company has granted the Underwriter an option, exercisable for 30 days
after the date of this Prospectus, to purchase up to an additional $15,000,000
principal amount of Debentures to cover over-allotments, if any, at the public
offering price set forth on the cover page hereof, less the underwriting
discount.

     The Company has been advised by the Underwriter that the Underwriter
presently intends to make a market in the Debentures offered hereby; however, it
is not obligated to do so.  Any market making may be discontinued at any time
without notice, and there can be no assurance that an active public market for
the Debentures will develop.

     The Company and SN Investors have agreed not to sell, contract to sell,
transfer or otherwise dispose of, directly or indirectly, any Common Stock, any
securities convertible into or exchangeable for Common Stock or any rights to
purchase or acquire Common Stock for a period of 60 days after the date of this
Prospectus without the prior written consent of the Underwriter, other than (i)
Common Stock issuable upon the exchange of the Debentures; (ii) Common Stock
issued or sold pursuant to employee benefit plans; (iii) Common Stock issued
upon exercise of currently outstanding options or warrants; or (iv) Common Stock
issued in connection with investments in, acquisitions of, or mergers or other
combinations with other companies.

     The Company has agreed to indemnify the Underwriter against certain
liabilities, including certain liabilities under the Securities Act, or to
contribute to payments the Underwriter may be required to make in respect
thereof.

     As set forth on the cover page of this Prospectus, at the request of the
Company, the Underwriter has reserved a portion of the Debentures for sale at
the initial offering price to certain directors, officers and employees of, and
consultants to, the Company and its subsidiaries.  The aggregate principal
amount of Debentures available for sale to the general public will be reduced to
the extent such persons purchase such Debentures.  Any reserved Debentures not
so purchased will be offered by the Underwriter to the general public on the
same basis as the other Debentures offered by this Prospectus.

                                 LEGAL MATTERS

     Certain legal matters with respect to the legality of the issuance of the
Debentures offered hereby will be passed upon for the Company by Shearman &
Sterling, New York, New York.  Certain legal matters will be passed upon for the
Underwriter by Brown & Wood LLP, New York, New York.  Shearman & Sterling is a
limited partner in SN Investors.

     The statements of law under the caption "Risk Factors--Government
Regulation of Porex" in this Prospectus and under the caption "Business--Porex--
Regulation" in the Company's 1996 10-K, incorporated by reference herein, are

                                       35
<PAGE>
 
based upon the opinion of Emens, Kegler, Brown, Hill & Ritter Co., L.P.A.,
Columbus, Ohio, special regulatory counsel to the Company.  Robert D. Marotta,
Esq., of counsel to such firm, holds 75,000 options to purchase Common Stock.

                                    EXPERTS

     The audited Consolidated Financial Statements and schedules of the Company
that are incorporated by reference into this Prospectus have been audited by
Arthur Andersen LLP, independent public accountants, as indicated in their
report with respect thereto, and are included herein in reliance upon the
authority of said firm as experts in accounting and auditing in giving said
report.

                                       36
<PAGE>
 
                        INDEX TO UNAUDITED CONSOLIDATED
                              FINANCIAL STATEMENTS

<TABLE>
<CAPTION>
                                                                                Page
                                                                                ----
<S>                                                                             <C>
 
          FINANCIAL INFORMATION:
 
          Financial Statements
 
          Consolidated Balance Sheets -- December 31, 1996 and June 30, 1996    F-2
 
          Consolidated Statements of Income --
               Six Months Ended December 31, 1996 and 1995                      F-4
 
          Consolidated Statements of Cash Flows --
               Six Months Ended December 31, 1996 and 1995                      F-5
 
          Notes to Consolidated Financial Statements                            F-6
 
          Management's Discussion and Analysis of Results of Operations
               and Financial Condition                                          F-9
</TABLE> 
 
                   ---------------                         

                                      F-1
<PAGE>
 
                         SYNETIC INC. AND SUBSIDIARIES
                          CONSOLIDATED BALANCE SHEETS
                                 (in thousands)

                                     ASSETS
<TABLE>
<CAPTION>
 
                                                                            December 31,    June 30,
                                                                                1996          1996
                                                                            -------------  ----------
<S>                                                                         <C>            <C>
                                                                            (unaudited)
CURRENT ASSETS:
  Cash and cash equivalents...............................................      $ 20,538    $ 22,210
  Marketable securities...................................................       151,013     140,268
            Accounts receivable, net of allowances for doubtful accounts           6,889       7,299
             and sales returns of $643 and $671 at December 31, 1996
             and June 30, 1996, respectively..............................
  Inventories.............................................................         5,871       5,253
  Other current assets....................................................         3,817       4,821
                                                                                --------    --------
    Total current assets..................................................       188,128     179,851
                                                                                --------    --------
 
PROPERTY, PLANT AND EQUIPMENT:
  Land and improvements...................................................           823         823
  Building and improvements...............................................         9,292       8,992
  Machinery and equipment.................................................        20,965      19,295
  Furniture and fixtures..................................................         2,966       2,856
  Construction in progress................................................         2,029       1,306
                                                                                --------    --------
                                                                                  36,075      33,272
  Less:  Accumulated depreciation.........................................       (17,255)    (16,014)
                                                                                --------    --------
    Property, plant and equipment, net....................................        18,820      17,258
                                                                                --------    --------
OTHER ASSETS:
  Other...................................................................         3,765       2,483
                                                                                --------    --------
    Total other assets....................................................         3,765       2,483
                                                                                --------    --------
                                                                                $210,713    $199,592
                                                                                ========    ========
</TABLE>
The accompanying notes are an integral part of these consolidated balance
sheets.

                                      F-2
<PAGE>
 
                         SYNETIC INC. AND SUBSIDIARIES
                          CONSOLIDATED BALANCE SHEETS
                     (in thousands, except per share data)

                      LIABILITIES AND STOCKHOLDERS' EQUITY
<TABLE>
<CAPTION>
 
                                                                       December 31,    June 30,
                                                                           1996          1996
                                                                       -------------  ----------
<S>                                                                    <C>            <C>
                                                                       (unaudited)
CURRENT LIABILITIES:
  Accounts payable...................................................      $  1,538    $  1,303
  Accrued liabilities................................................        12,932       7,014
  Income taxes payable...............................................         4,014       5,206
                                                                           --------    --------
    Total current liabilities........................................        18,484      13,523
                                                                           --------    --------
DEFERRED TAXES AND OTHER LIABILITIES.................................         8,728       4,980
 
STOCKHOLDERS' EQUITY:
            Preferred stock, $.01 par value; 10,000,000 shares                   --          --
             authorized; none issued.................................
            Common stock,$.01 par value; 50,000,000 shares                      226         220
             authorized; 17,323,958 and 16,738,827 shares issued at
             December 31, 1996 and June 30, 1996, respectively.......
  Paid-in capital....................................................       185,890     158,227
  Treasury stock, at cost; 5,268,463 shares at December 31, 1996.....       (38,287)    (36,575)
  Retained earnings..................................................        35,672      59,217
                                                                           --------    --------
    Total stockholders' equity.......................................       183,501     181,089
                                                                           --------    --------
                                                                           $210,713    $199,592
                                                                           ========    ========
 
</TABLE>
The accompanying notes are an integral part of these consolidated balance
sheets.

                                      F-3
<PAGE>
 
                         SYNETIC, INC. AND SUBSIDIARIES
                       CONSOLIDATED STATEMENTS OF INCOME
            Quarters and Six Months Ended December 31, 1996 and 1995
                     (in thousands, except per share data)
                                  (unaudited)
<TABLE>
<CAPTION>
 
 
                                                Quarters Ended        Six Months Ended
                                                 December 31,            December 31,
                                               1996       1995        1996         1995         
                                            ----------  ---------  ----------   ----------      
<S>                                         <C>         <C>        <C>          <C>             
Net Sales.................................   $ 11,899    $10,283    $ 23,084       $21,319      
   Cost of sales..........................      6,348      5,820      12,474        12,160      
   Selling, general and administrative....      3,839      3,337       7,590         6,949      
   Interest and other income..............     (2,343)    (1,998)     (4,562)       (4,041)     
   Other expenses.........................     28,600         --      28,600            --      
                                             --------    -------    --------       -------      
Income before provision for income taxes..    (24,545)     3,124     (21,018)        6,251      
Provision for income taxes................      1,389      1,051       2,527         2,254      
                                             --------    -------    --------       -------      
Net income (loss).........................   $(25,934)   $ 2,073    $(23,545)      $ 3,997      
                                             ========    =======    ========       =======      
Net income (loss) per share...............     $(1.39)      $.12      $(1.28)         $.22      
                                             ========    =======    ========       =======      
Weighted average shares outstanding.......     18,653     17,885      18,455        17,858      
                                             ========    =======    ========       =======      
 
 
</TABLE>
The accompanying notes are an integral part of these consolidated statements.

                                      F-4
<PAGE>
 
                         SYNETIC, INC. AND SUBSIDIARIES
                     CONSOLIDATED STATEMENTS OF CASH FLOWS
                  Six Months Ended December 31, 1996 and 1995
                     (in thousands, except per share data)
                                  (unaudited)
<TABLE>
<CAPTION>
 
Cash flows from operating activities:                                               1996        1995
                                                                                 ----------  ----------
<S>                                                                              <C>         <C>
Net income (loss)..............................................................  $ (23,545)  $   3,997
Adjustments to reconcile net income (loss) to
   net cash provided by operating activities:..................................
       Write-off of purchased research and
         development costs.....................................................     28,600          --
       Depreciation and amortization...........................................      1,163       1,294
 
Changes in operating assets and liabilities:
   Accounts receivable, net....................................................        410         341
   Inventories.................................................................       (618)        522
   Other assets................................................................      1,277         182
   Accounts payable............................................................        235         108
   Accrued liabilities.........................................................         96      (4,110)
   Income taxes payable........................................................      3,351        (378)
                                                                                 ---------   ---------
       Net cash provided by (used for)
         operating activities..................................................  $  10,969   $   1,956
                                                                                 ---------   ---------
 
Cash flows from investing activities:
   Sales of marketable securities..............................................    218,457     338,443
   Purchase of marketable securities...........................................   (229,202)   (334,800)
   Capital expenditures........................................................     (2,668)     (1,234)
   Acquisition of businesses, net of cash
     acquired..................................................................        596          --
                                                                                 ---------   --------- 
       Net cash provided by (used for)
         investing activities..................................................    (12,817)      2,409
                                                                                 ---------   --------- 
 
Cash flows from financing activities:
   Payments for treasury stock.................................................     (1,712)         --
   Proceeds from exercise of stock options and
     401(k) purchases..........................................................      1,888         808
   Payments of long-term debt..................................................         --        (216)
                                                                                 ---------   ---------
       Net cash provided by (used for)
         financing activities..................................................        176         592
                                                                                 ---------   ---------
 
Net increase (decrease) in cash and
  cash equivalents.............................................................     (1,672)      4,957
Cash and cash equivalents, beginning of period.................................     22,210       7,499
                                                                                 ---------   ---------
Cash and cash equivalents, end of period.......................................  $  20,538   $  12,456
                                                                                 =========   =========
 
The accompanying notes are an integral part of these consolidated statements.
</TABLE>

                                      F-5
<PAGE>
 
                         SYNETIC, INC. AND SUBSIDIARIES
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

(1)  Financial statement presentation:

     In the opinion of management, the accompanying consolidated financial
statements contain all normal and recurring adjustments necessary to present
fairly the financial position of Synetic, Inc. and subsidiaries (the "Company")
as of December 31, 1996 (unaudited) and June 30, 1996 (audited), and the results
of their operations and their cash flows for the six months ended December 31,
1996 and 1995 (unaudited).

     Principles of Consolidation--

     The accompanying consolidated financial statements include the accounts of
the Company and its wholly owned operating subsidiaries, Porex Technologies
Corp. ("Porex") and Avicenna Systems Corp., after elimination of all material
intercompany accounts and transactions.

     The accounting policies followed by the Company are set forth in the Notes
to Consolidated Financial Statements included in the Company's Annual Report on
Form 10-K for the fiscal year ended June 30, 1996 (the "1996 10-K"), which notes
are incorporated herein by reference.

     The results of operations for the interim periods presented are not
necessarily indicative of the results to be expected for the full fiscal year.

     Certain reclassifications have been made to prior year amounts to conform
to the current year presentation.

(2)  Inventories:

     Inventories consisted of the following (in thousands):

 
                                December 31,  June 30,
                                    1996        1996
                                ------------ ----------
                                 (unaudited)
Raw materials and supplies..        $2,621     $2,468
Work-in-process.............           517        548
Finished goods..............         2,733      2,237
                                    ------     ------
                                    $5,871     $5,253
                                    ======     ======

(3)  Marketable securities:

     At December 31, 1996, marketable securities consisted primarily of U.S.
Treasury Notes, U.S. Agency Notes and Money Market Preferred Stock.

(4)  Computation of net income per share:

     Net income per share is determined by dividing net income by the weighted
average number of shares of common stock and common stock equivalents
outstanding during the applicable period.  Common stock equivalents consist of
common stock which may be issuable upon exercise of outstanding stock options as
calculated using the treasury stock method.

                                      F-6
<PAGE>
 
(5)  Supplemental cash flow information (in thousands):

     For the six months ended December 31, 1996 and 1995, the Company recognized
tax benefits related to the exercise of stock options as increases to additional
paid-in capital and decreases to income taxes payable of $4,542,000 and
$248,000, respectively.

 
                                      December 31,
                                     --------------
Cash paid during the periods for:     1996    1995
                                     ------  ------
    Interest.......................  $  --   $    6
    Income taxes...................   1,239   2,414
 

(6)  Acquisitions:

     Avicenna --

     On December 24, 1996, the Company acquired the outstanding equity and
indebtedness (including employee stock options) of Avicenna Systems Corp.
("Avicenna"), a privately held, development stage company located in Cambridge,
Massachusetts, for shares of the Company's common stock with a market value of
$30.5 million. As additional consideration, the Company agreed to issue to
certain sellers, nontransferable warrants covering 250,000 shares of Synetic,
Inc., exercisable after December 23, 1998 at a price of $54.50 per share.
Avicenna's business plan has been to market and build Intranets for managed care
organizations, hospitals and physician groups. The acquisition was accounted for
using the purchase method with the purchase price being allocated to assets
acquired and liabilities assumed based on their appraised fair values.
Avicenna's results of operations have been included in the Company's financial
statements as of December 24, 1996.

     A summary of the purchase price allocation is as follows (in thousands):


          Cash................................   $    42
          Short-term investments..............       240
          Other assets........................       216
          Property, plant and equipment.......       759
          Purchased research and development..    28,600
          Intangible assets...................     1,502
          Goodwill............................       116
                                                 -------
                                                 $31,475
                                                 ------- 

     The amount allocated to purchased research and development of $28.6 million
was determined based on an appraisal using known valuation techniques and was
immediately expensed with no corresponding tax benefit in the period of
acquisition because such research and development was in process and had no
alternative commercial use. Remaining amounts have been allocated to intangible
assets and goodwill.

                                      F-7
<PAGE>
 
     The following summary, prepared on a pro forma basis, combines the results
of operations of the Company and Avicenna assuming the acquisition was
consummated at the beginning of the period presented (in thousands, except per
share amount):
 
                                        Six months ended 
                                       December 31, 1996 
                                       ------------------
                                          (unaudited)    
                 Sales...............           $ 23,084 
                 Net Loss............            (25,466)
                 Net Loss per share..           $  (1.35) 

     The pro forma results are not necessarily indicative of what actually would
have occurred if the acquisition had been in effect for the entire period
presented.  In addition, they are not intended to be a projection of future
results.  The pro forma impact of the acquisition for the six months ended
December 31, 1995 was not material.

     CareAgents, Inc.--

     On January 23, 1996, the Company acquired privately held CareAgents, Inc.
("CareAgents") to add management resources with expertise in large-scale
commercial clinical applications, medicine and information technology.
CareAgents was an early development stage company focussed on developing
Internet-based clinical commerce applications. The Company acquired CareAgents
for shares of the Company's common stock with a market value of $5.0 million.
Such acquisition will be recorded in the quarter ended March 31,1997. The
Company expects to record a non-recurring charge to expense in the quarter ended
March 31, 1997 relating to purchased research and development costs in
conjunction with its acquisition of CareAgents in January 1997. While the exact
amount of the charge is not yet determinable, the Company does not expect this
charge to exceed $3 million.

                                      F-8
<PAGE>
 
     MANAGEMENT'S DISCUSSION AND ANALYSIS OF
     RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

QUARTER AND SIX MONTHS ENDED DECEMBER 31, 1996 COMPARED WITH QUARTER AND SIX
MONTHS ENDED DECEMBER 31, 1995.

Consolidated Results of Operations:
- ---------------------------------- 

     Net sales for the quarter and six months ended December 31, 1996 increased
by $1,616,000, or 15.7%, and $1,765,000, or 8.3%, respectively, over the
comparable prior year periods as a result of sales improvements across several
product lines. The increase in sales was due principally to an increase in sales
of medical OEM porous and surgical products in the Healthcare sector and writing
instrument components in the Consumer sector.

     Cost of sales for the quarter and six months ended December 31, 1996
increased by $528,000, or 19.1%, and $314,000, or 2.6%, respectively, over the
comparable prior year periods due to the increase in sales volume noted above.
As a percent of net sales, cost of sales for the quarter and six months ended
December 31, 1996 decreased to 53.3% and 54.0% from 56.6% and 57.0%,
respectively, in the comparable prior year periods due principally to an
improvement in labor utilization and the leverage of fixed manufacturing costs.

     Selling, general and administrative expenses for the quarter and six months
ended December 31, 1996 increased by $502,000, or 15%, and $641,000, or 9.2%,
respectively, over the comparable prior year periods due primarily to an
increase in expenses associated with the increase in sales volume noted above
and an increase in corporate overhead expenses.  As a percent of net sales,
selling, general and administrative expenses for the quarter and six months
ended December 31, 1996 did not vary materially from the comparable prior year
periods.

     Interest and other income for the quarter and six months ended December 31,
1996 increased by $345,000, or 17.3%, and $521,000, or 12.9%, respectively, over
the comparable prior year periods principally as a result of an increase in
funds available for investment generated by cash flow from operations.

     During the quarter ended December 31, 1996, the Company recorded a charge
to income of $28,600,000 for purchased research and development ("R&D") costs
relating to the acquisition of Avicenna.

     Excluding the R&D charge discussed above, for which no tax benefit is
recognized, the effective tax rate for the quarter ended December 31, 1996
remained relatively constant at 34% as compared to the prior year period. For
the six months ended December 31, 1996, the effective tax rate decreased to 34%
from 36% primarily due to an increase in income in the current year eligible for
dividends received deductions.

Capital Resources and Liquidity:
- ------------------------------- 

     Cash, cash equivalents and marketable securities increased by $9,073,000 to
$171,551,000 during the six months ended December 31, 1996 principally due to
the income earned from operations. Of the $171,551,000 in cash and marketable
securities, $157,238,000 is attributable to Synetic and not its subsidiaries and
$14,313,000 is attributable to Porex.

     The Company believes that its cash flow from operations, cash and
marketable securities and the income earned on its investments are sufficient to
meet the anticipated working capital requirements of its business.

                                      F-9
<PAGE>
 
     As a result of the acquisition of Avicenna and CareAgents, the Company
expects to incur significant research and development expenses and incur
additional operating losses in connection with this new area of business until
the products and services are successfully developed or marketed.  There can be
no assurances that the products or services will be successfully developed or
marketed.  The rate of aggregate expenditures at Avicenna and CareAgents
immediately prior to their acquisition was approximately $1,600,000 per quarter.
Research and development expenses may be materially greater in the future than
current amounts until the Company successfully develops its products and
services.  The Company, however, anticipates that such research and development
expenses will not exceed $2,500,000 per fiscal quarter for the third and fourth
quarters of the fiscal year ending June 30, 1997 and will not result in net
losses for the current fiscal year (excluding the non-recurring charges for
purchased research and development costs relating to the acquisition of Avicenna
and CareAgents) or for either of the fiscal quarters ending March 31, 1997 or
June 30, 1997.

     The Company continues to pursue an acquisition program pursuant to which it
seeks to effect one or more acquisitions or other similar business combinations
with businesses it believes have significant growth potential.  Financing for
such acquisitions may come from several other sources, including, without
limitation, (a) its cash, cash equivalents and marketable securities and (b)
proceeds from the incurrence of additional indebtedness or the issuance of
common stock, preferred stock, convertible debt or other securities. The Company
currently intends to use the net proceeds from the sale of the Debentures for
general corporate purposes, which may include acquisitions. For a further
description of the Company's Acquisition Program, see "Risk Factors--Acquisition
Program" and "Business--Acquisition Program".

                                     F-10
<PAGE>
 
          -----------------------------------------------------------

NO DEALER, SALESPERSON OR OTHER INDIVIDUAL HAS BEEN AUTHORIZED TO GIVE ANY
INFORMATION OR TO MAKE ANY REPRESENTATIONS OTHER THAN THOSE CONTAINED OR
INCORPORATED BY REFERENCE IN THIS PROSPECTUS IN CONNECTION WITH THE OFFER MADE
BY THIS PROSPECTUS.  IF GIVEN OR MADE, SUCH INFORMATION OR REPRESENTATIONS MUST
NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED BY THE COMPANY OR THE UNDERWRITER.
THIS PROSPECTUS DOES NOT CONSTITUTE AN OFFER TO SELL OR A SOLICITATION OF AN
OFFER TO BUY THE DEBENTURES OFFERED HEREBY IN ANY JURISDICTION IN WHICH, OR TO
ANY PERSON TO WHOM, IT IS UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION.  NEITHER
THE DELIVERY OF THIS PROSPECTUS NOR ANY SALES MADE HEREUNDER SHALL, UNDER ANY
CIRCUMSTANCES, CREATE ANY IMPLICATION THAT THERE HAS BEEN NO CHANGE IN THE
AFFAIRS OF THE COMPANY SINCE THE DATE HEREOF.

                             _____________________


                               TABLE OF CONTENTS

                                                   Page                  
                                                   ----          
                Available Information............     1          
                Incorporation of Certain                         
                  Documents by Reference.........     2          
                Prospectus Summary...............     3          
                Risk Factors.....................     8          
                Use of Proceeds..................    14          
                Price Range of Common Stock......    14          
                Dividend Policy..................    14          
                Capitalization...................    15          
                Business.........................    16          
                Management.......................    22          
                Description of Debentures........    25          
                Description of Capital Stock.....    32          
                Shares Eligible for Future Sale..    33          
                Underwriting.....................    35          
                Legal Matters....................    35          
                Experts..........................    36          
                Index to Unaudited Consolidated                  
                    Financial Statements.........   F-1          


          ===========================================================

          ===========================================================




                                  $100,000,000


                                 SYNETIC, INC.


                                 _% CONVERTIBLE
                                  SUBORDINATED
                              DEBENTURES DUE 2007



                                 ______________

                                   PROSPECTUS
                                 ______________



                              MERRILL LYNCH & CO.



                                     , 1997

          ===========================================================
                                          
<PAGE>
 
                                    PART II


                     INFORMATION NOT REQUIRED IN PROSPECTUS


ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

     The following expenses, other than the Securities and Exchange Commission
registration fee, are estimated.  All expenses of the offering will be paid by
the Company.

  SEC Registration Fee.........................    $34,849
  Printing and Engraving.......................
  Legal Fees and Expenses......................
  Accounting Fees and Expenses.................
  Trustee's Fees...............................
  Blue Sky Fees and Expenses...................
  Miscellaneous................................
                                                   ___ ___
     Total                                         $
                                                   =======

ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

     Section 145 of the General Corporation Law of the State of Delaware (the
"DGCL") provides, in summary, that directors and officers of Delaware
corporations such as the Registrant are entitled, under certain circumstances,
to be indemnified against all expenses and liabilities (including attorneys'
fees) incurred by them as a result of suits brought against them in their
capacity as a director or officer if they acted in good faith and in a manner
they reasonably believed to be in or not opposed to the best interests of the
Registrant and, with respect to any criminal action or proceeding, if they had
no reasonable cause to believe their conduct was unlawful; provided that no
indemnification may be made against expenses in respect of any claim, issue or
matter as to which they shall have been adjudged to be liable to the Registrant,
unless and only to the extent that the court in which such action or suit was
brought shall determine upon application that, despite the adjudication of
liability but in view of all the circumstances of the case, they are fairly and
reasonably entitled to indemnity for such expenses which such court shall deem
proper.  Any such indemnification may be made by the company only as authorized
in each specific case upon a determination by the stockholders or disinterested
directors that indemnification is proper because the indemnitee has met the
applicable standard of conduct.  Article Eleven of the Registrant's Certificate
of Incorporation and Section 6.5 of the Registrant's By-Laws entitles officers,
directors and controlling persons of the Registrant to indemnification to the
full extent permitted by Section 145 of the DGCL, as the same may be
supplemented or amended from time to time.

     Article Thirteen of the Registrant's Certificate of Incorporation provides
that no director shall have any personal liability to the Registrant or its
stockholders for any monetary damages for breach of fiduciary duty as a
director, provided that such provision does not limit or eliminate the liability
of any director (i) for breach of such director's duty of loyalty to the
Registrant or its stockholders, (ii) for acts or omissions not in good faith or
which involve intentional misconduct or a knowing violation of law, (iii) under
Section 174 of the DGCL (involving certain unlawful dividends or stock
repurchase) or (iv) for any transaction from which such director derived an
improper personal benefit.  Amendment to such article does not affect the
liability of any director for any act or omission occurring prior to the
effective time of such amendment.

     Reference is made to the Form of Indemnification Agreement between the
Registrant and its directors and officers filed as Exhibit 10.1 to this
Registration Statement pursuant to which the registrant has agreed to indemnify
such directors and officers to the fullest extent permitted by Delaware law, as
the same may be amended from time to time.

                                      II-1
<PAGE>
 
ITEM 16.  EXHIBITS

          Exhibits:

     1.1  Form of Purchase Agreement.

     4.1  Specimen Common Stock Certificate of the Registrant.  Incorporated by
          reference to Exhibit 4.1 to the Registrant's Registration Statement on
          Form S-1 (No. 33-28654) (the "Registration Statement").

     4.2  Form of Indenture to be dated as of _____________________, between the
          Registrant and United States Trust Company of New York, including form
          of _____% Convertible Subordinated Debenture due 2007.

     4.3  Certificate of Incorporation of the Company, as amended.  Incorporated
          by reference to Exhibit 3.1 to the Company's Registration Statement on
          Form S-1 (No. 33-28654).

     4.4  By-Laws of the Company, as amended.  Incorporated by reference to
          Exhibit 3.2 to the Company's Annual Report on Form 10-K for the fiscal
          year ended June 30, 1994.

     5.1  Opinion of Shearman & Sterling.

     10.1 Form of Indemnification Agreement between the Company and the
          directors and officers of the Company.  Incorporated by reference to
          Exhibit 10.6 to the Registration Statement.

     12.1 Calculation of ratios of earnings to fixed charges.
 
     23.1 Consent of Arthur Andersen LLP.

     23.2 Consent of Emens, Kegler, Brown, Hill & Ritter Co., L.P.A.

     23.3 Consent of Shearman & Sterling (included in Exhibit 5.1).

     24.1 Powers of Attorney of the Registrant.

     25.1 Form T-1 Statement of Eligibility and Qualification of United States
          Trust Company of New York.


ITEM 17.  UNDERTAKINGS

     (a) The undersigned Registrant hereby undertakes that:

          (1) For purposes of determining any liability under the Securities Act
     of 1933, the information omitted from the form of prospectus filed as part
     of this registration statement in reliance upon Rule 430A and contained in
     a form of prospectus filed by the registrant pursuant to Rule 424(b)(1) or
     (4) or 497(h) under the Securities Act shall be deemed to be part of this
     registration statement as of the time it was declared effective.

          (2) For the purpose of determining any liability under the Securities
     Act of 1933, each post-effective amendment that contains a form of
     prospectus shall be deemed to be a new registration statement relating to
     the securities offered therein, and the

                                      II-2
<PAGE>
 
     offering of such securities at that time shall be deemed to be the initial
     bona fide offering thereof.

     (b) The undersigned Registrant hereby undertakes that, for purposes of
determining any liability under the Securities Act of 1933, each filing of the
Registrant's annual report pursuant to Section 13(a) or 15(d) of the Securities
Exchange Act of 1934 (and, where applicable, each filing of an employee benefit
plan's annual report pursuant to Section 15(d) of the Securities Exchange Act of
1934) that is incorporated by reference in this Registration Statement shall be
deemed to be a new Registration Statement relating to the securities offered
herein, and the offering of such securities at that time shall be deemed to be
the initial bona fide offering thereof.

     (c) Insofar as indemnification for liabilities arising under the Securities
Act of 1933 may be permitted to directors, officers and controlling persons of
the Registrant pursuant to the foregoing provisions, or otherwise, the
Registrant has been advised that in the opinion of the Securities and Exchange
Commission such indemnification is against public policy as expressed in the
Act and is, therefore, unenforceable.  In the event that a claim for
indemnification against such liabilities (other than the payment by the
Registrant of expenses incurred or paid by a director, officer or controlling
person of the Registrant in the successful defense of any action, suit or
proceeding) is asserted by such director, officer, or controlling person in
connection with the securities being registered hereby, the Registrant will,
unless in the opinion of its counsel the matter has been settled by controlling
precedent, submit to a court of appropriate jurisdiction the question whether
such indemnification by it is against public policy as expressed in the Act and
will be governed by the final adjudication of such issue.

                                      II-3
<PAGE>
 
                                  SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the Registrant,
Synetic, Inc., a corporation organized and existing under the laws of the State
of Delaware, certifies that it has reasonable grounds to believe that it meets
all of the requirements for filing on Form S-3 and has duly caused this
Registration Statement to be signed on its behalf by the undersigned, thereunto
duly authorized, in the Borough of Elmwood Park, State of New Jersey, on the 3rd
day of February, 1997.


                                    SYNETIC, INC.


                                    By  /s/Victor L. Marrero
                                        --------------------
                                        Victor L. Marrero
                                        Vice President--Finance and     
                                        Chief Financial Officer

     Pursuant to the requirements of the Securities Act of 1933, this
Registration Statement has been signed below by the following persons in the
capacities and on the date indicated.
<TABLE>
<CAPTION>
 
 
 
         Signature                               Title                            Date
         ---------                               -----                            ----
<S>                           <C>                                           <C>
 
 
             *                      President and Chief Executive Officer;  February 3, 1997 
- ----------------------------        Director
     James V. Manning             
                 
 
             *                      Vice President--Technologies Group;     February 3, 1997 
- ----------------------------        Director
       Ray E. Hannah
 
 
/s/  Victor L. Marrero              Vice President--Finance and Chief
- ----------------------------        Financial Officer (Principal Accounting 
     Victor L. Marrero              and Financial Officer)                  February 3, 1997 
                  
 
             *                      Vice President--General Counsel;        February 3, 1997 
- ----------------------------        Director 
      Charles A. Mele
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
    Thomas R. Ferguson
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
    Mervyn L. Goldstein
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
      Roger H. Licht
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
     Per G. H. Lofberg
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
      Herman Sarkowsky
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
      Paul C. Suthern
</TABLE> 

                                      II-4
<PAGE>

<TABLE> 
<S>                                 <C>                                     <C>  
             *                      Director                                February 3, 1997 
- ----------------------------  
       Albert M. Weis
 
 
             *                      Director                                February 3, 1997 
- ----------------------------  
      Martin J. Wygod
 
*By   /s/Victor L. Marrero                                                  February 3, 1997 
Victor L. Marrero
Attorney-in-fact
============================================================================================
</TABLE>

                                      II-5
<PAGE>
 
                               INDEX TO EXHIBITS


Exhibit
  No.          Description of Document
- -------        -----------------------

1.1            Form of Purchase Agreement

4.1            Specimen Common Stock Certificate of the Registrant.
               Incorporated by reference to Exhibit 4.1 to the Registrant's
               Registration Statement on Form S-1 (No. 33-28654) (the
               "Registration Statement")

4.2            Form of Indenture to be dated as of __________, between the
               Registrant and United States Trust Company of New York, including
               form of ________% Convertible Subordinated Debenture due 2007.

4.3            Certificate of Incorporation of the Company,
               as amended.  Incorporated by reference to
               Exhibit 3.1 to the Company's Registration
               Statement on Form S-1 (No. 33-28654) (the
               "Registration Statement")

4.4            By-Laws of the Company, as amended.
               Incorporated by reference to Exhibit 3.2 to
               the Company's Annual Report on Form 10-K
               for the fiscal year ended June 30, 1994

5.1            Opinion of Shearman & Sterling

10.1           Form of Indemnification Agreement between
               the Company and the directors and officers of
               the Company.  Incorporated by reference to
               Exhibit 10.6 to the Registration Statement

12.1*          Calculation of ratios of earnings to fixed charges.

23.1*          Consent of Arthur Andersen LLP

23.2*          Consent of Emens, Kegler, Brown,
               Hill & Ritter Co., L.P.A.

23.3           Consent of Shearman & Sterling
               (included in Exhibit 5.1)

24.1*          Powers of Attorney of the Registrant

25.1           Form T-1 Statement of Eligibility and Qualification of United
               States Trust Company of New York.
 
*Filed herewith

<PAGE>

                                                                    EXHIBIT 12.1

 
<TABLE> 
<CAPTION> 
                                                           SYNETIC, INC.

                                                RATIO OF EARNINGS TO FIXED CHARGES
                                                   (in thousands, except ratios)


                                                                                                                   
                                                                                                 Six Months Ended  
                                                                Year Ended June 30,                December 31,    
                                          -----------------------------------------------------  ----------------  
                                             1992      1993       1994       1995       1996       1995     1996   
                                          ---------  --------  ---------  ---------  ----------  -------   ------  
<S>                                      <C>        <C>       <C>        <C>        <C>         <C>       <C>      
                                                                                                                   
Fixed Charges:                                                                                                     
  Interest expense                         $3,405     $3,786    $5,734     $3,469         --         --       --   
  Amortization of debt insurance costs        143        241       241        150         --         --       --   
  Estimated interest element of                                                                                    
    rental payments                            65         46        49         66        106         33        53  
                                          ---------  --------- ---------  ---------  ----------  -------   ------- 
        Total fixed charges                 3,613      6,073     6,024      3,685        106         33        53  

Adjusted earnings(1):
  Add: Income from continuing 
    operations before income taxes          6,031      5,430     1,643 (2)  7,741 (3) 13,202      6,251     7,582 (4)
                                          ---------  --------- ---------  ---------  ----------  -------   -------  
      Adjusted earnings                    $9,644    $11,503   $ 7,667    $11,426    $13,308     $6,284    $7,635   
                                          =========  ========= =========  =========  ==========  =======   =======  
Ratio of earnings to fixed charges            2.7 x      1.9 x     1.3 x      3.1 x    125.5 x    191.4 x   144.1 x 
                                          =========  ========= =========  =========  ==========  =======   =======  

</TABLE> 

(1)  Earnings used in computing the ratio of earnings to fixed charges consist
     of earnings from continuing operations before taxes, excluding non-
     recurring charges, and fixed charges. Fixed charges consist of interest
     expense, amortization of debt issuance costs and the estimated interest
     element of rental payments.

(2)  Excludes a non-recurring charge consisting of one-time payments in the
     aggregate of $563 made to certain executive officers in conjunction with
     the acquisition of the Company's former parent company.

(3)  Excludes non-recurring charges of: (i) $5,580 primarily related to the
     award of stock options to certain officers in connection with the
     completion of the sale of the Institutional pharmacy business and the
     purchase of shares of Company stock owned by Merck & Co., Inc., and (ii)
     $1.083 related to the conversion and redemption of the Company's debentures
     in February 1995.

(4)  Excludes a non-recurring charge consisting of the write-off of purchased
     research and development costs of $28,600 associated with the Company's
     purchase of Avicenna Systems Corp.




<PAGE>
 
                                                                    EXHIBIT 23.1

                   CONSENT OF INDEPENDENT PUBLIC ACCOUNTANTS


As independent public accountants, we hereby consent to the incorporation by 
reference in this Registration Statement on Form S-3 of our report dated 
September 27, 1996 included in Synetic, Inc.'s Annual Report on Form 10-K for 
the fiscal year ended June 30, 1996, and to all references to our Firm in this 
Registration Statement.


                                                /s/ Arthur Andersen LLP

                                                ARTHUR ANDERSEN LLP


New York, New York
January 31, 1997
                                                

<PAGE>
 
              [Letterhead of EMENS, KEGLER, BROWN, HILL & RITTER]
                                                                        Ex. 23.2

Dear Ladies and Gentlemen:

        We hereby consent to the incorporation by reference into the Synetic,
Inc. Registration Statement on Form S-3 (File No. 333-     ) filed with the
Securities and Exchange Commission, of the Company's Annual Report on Form 10-K
for the fiscal year ended June 30, 1996.  We also consent to all references to 
our firm included in such Registration Statement.


Columbus, Ohio
January 31, 1997                            Very truly yours,
                        
                                            EMENS, KEGLER, BROWN, HILL
                                              & RITTER CO., L.P.A.



                                            By: /s/ Jack A. Bjerke
                                                ------------------------------
                                                Jack A. Bjerke, Vice President

<PAGE>
 
                                                                        EX. 24.1
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ James V. Manning
                                                --------------------------
                                                Signature

                                                JAMES V. MANNING
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Ray E. Hannah
                                                --------------------------
                                                Signature

                                                RAY E. HANNAH
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.



                                                /s/ Charles A. Mele
                                                --------------------------
                                                Signature
                                               
                                                CHARLES A. MELE
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Thomas R. Ferguson
                                                --------------------------
                                                Signature

                                                THOMAS R. FERGUSON
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Mervyn L. Goldstein
                                                --------------------------
                                                Signature

                                                MERVYN L. GOLDSTEIN
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Roger Licht
                                                --------------------------
                                                Signature

                                                /s/ ROGER LICHT
                                                --------------------------
                                                Print Name

<PAGE>
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Per G.H. Lofberg
                                                --------------------------
                                                Signature


                                                PER G.H. LOFBERG
                                                --------------------------
                                                Print Name

<PAGE>
 
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Herman Sarkowsky
                                                --------------------------
                                                Signature

                                                HERMAN SARKOWSKY
                                                --------------------------
                                                Print Name

<PAGE>
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Paul C. Suthern
                                                --------------------------
                                                Signature

                                                PAUL C. SUTHERN
                                                --------------------------
                                                Print Name

<PAGE>
 

                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Albert Weis
                                                --------------------------
                                                Signature

                                                ALBERT WEIS
                                                --------------------------
                                                Print Name

<PAGE>
 
                                 SYNETIC, INC.

                               POWER OF ATTORNEY

        KNOWN ALL MEN BY THESE PRESENTS, that the undersigned does hereby 
constitute and appoint James V. Manning, Charles A. Mele and Victor L. Marrero,
and each of them, each with full power to act without the other, his true and 
lawful attorneys-in-fact and agents, EACH with full power of substitution and 
resubstitution, for him and in his name, place and stead, in any and all 
capacities, to sign a Registration Statement on Form S-3 (the "Registration 
Statement") relating to the sale of convertible debentures of Synetic, Inc. 
and to sign any and all amendments to the Registration Statement, and to file 
the same, with all exhibits thereto, and all other documents in connection 
therewith, with the Securities and Exchange Commission, granting unto said 
attorneys-in-fact and agents, full power and authority to do and perform each 
and every act and thing requisite and necessary to be done as fully to all 
intents and purposes as the undersigned might or could do in person, hereby 
ratifying and confirming all that said attorneys-in-fact and agents may 
lawfully do or cause to be done by virtue hereof.


        IN WITNESS WHEREOF, the undersigned has executed this Power of Attorney 
as of the 29th day of January, 1997.


                                                /s/ Martin J. Wygod
                                                --------------------------
                                                Signature

                                                MARTIN J. WYGOD
                                                --------------------------
                                                Print Name


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