NEOPATH INC
DEF 14A, 1998-04-09
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
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                     SCHEDULE 14A INFORMATION
    Proxy Statement Pursuant to Section 14(a) of the Securities
                       Exchange Act of 1934

   Filed by the Registrant  [x]
   Filed by a Party other than the Registrant  [ ]

   Check the appropriate box:
   [ ]  Preliminary Proxy Statement         [ ]  Confidfential, For Use of the
                                                 Commission Only (as permitted
                                                 by Rule 14a-6(e)(2))
   [x]  Definitive Proxy Statement
   [ ]  Definitive Additional Materials
   [ ]  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12
________________________________________________________________________________

                             NEOPATH, INC.
            (Name of Registrant as Specified in Its Charter)

________________________________________________________________________________
  (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of Filing Fee (Check the appropriate box):
   [x]  No fee required.
   [ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.
   (1)  Title of each class of securities to which transaction applies:

________________________________________________________________________________

   (2)  Aggregate number of securities to which transaction applies:

________________________________________________________________________________

   (3)  Per unit price or other underlying value of transaction computed 
        pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
        filing fee is calculated and state how it was determined):

________________________________________________________________________________

   (4)  Proposed maximum aggregate value of transaction:

________________________________________________________________________________

   (5)  Total fee paid:

________________________________________________________________________________

   [ ]  Fee paid previously with preliminary materials:

________________________________________________________________________________

   [ ]  Check box if any part of the fee is offset as provided by Exchange Act
Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid
previously.  Identify the previous filing by registration statement number, or
the form or schedule and the date of its filing.

   (1)  Amount previously paid:

________________________________________________________________________________

   (2)  Form, Schedule or Registration Statement no.:

________________________________________________________________________________

   (3)  Filing Party:

________________________________________________________________________________

   (4)  Date Filed:

________________________________________________________________________________

<PAGE>

                        [LOGO OF NEOPATH, INC.]
                                   
                          Redmond, Washington
                            April 14, 1998
                                   
                                   
                                   
                                   
Dear Shareholders:

      On  behalf of the Board of Directors and management, I cordially
invite  you  to attend the NeoPath, Inc. (the "Company")  1998  Annual
Meeting of Shareholders (the "Annual Meeting") to be held on Thursday,
May 21, 1998 at 8:30 a.m. (Pacific daylight time) at The Hyatt Regency
Bellevue at Bellevue Place, 900 Bellevue Way NE, Bellevue, Washington.

      At  the Annual Meeting, you will be asked to elect two directors
to  the  Company's Board of Directors and to consider and vote upon  a
proposal  to  amend the NeoPath, Inc. 1989 Restated Stock Option  Plan
(the "1989 Plan") to increase the number of shares issuable under  the
1989  Plan.  Your attention is directed to the accompanying Notice  of
Annual  Meeting of Shareholders and accompanying Proxy  Statement  for
further  information with respect to matters to be acted upon  at  the
Annual Meeting.

      NEOPATH'S  BOARD OF DIRECTORS RECOMMENDS THAT YOU VOTE  FOR  THE
ELECTION  OF  THE NOMINEES FOR DIRECTOR AND FOR THE AMENDMENT  TO  THE
1989 PLAN.

      Whether  or  not you plan to attend the Annual  Meeting,  it  is
important that your shares be represented.  Please sign, date and mail
the  enclosed  proxy card as soon as possible in the enclosed  postage
prepaid  envelope to ensure that your vote is counted.  If you  attend
the  meeting, you will, of course, have the right to vote your  shares
in person.

                                        Very truly yours,



                                        Alan C. Nelson
                                        President and
                                        Chief Executive Officer








                                   
                PLEASE COMPLETE, SIGN, DATE AND RETURN
                        THE ENCLOSED PROXY CARD

<PAGE>
                                   
                        [LOGO OF NEOPATH, INC.]
                                   
                        8271 - 154th Avenue NE
                      Redmond, Washington  98052
                                   
               NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
                                   
                        TO BE HELD MAY 21, 1998


To the Shareholders:

     The 1998 Annual Meeting of Shareholders (the "Annual Meeting") of
NeoPath, Inc., a Washington corporation (the "Company"), will be  held
at  The Hyatt Regency Bellevue at Bellevue Place, 900 Bellevue Way NE,
Bellevue, Washington, on Thursday, May 21, 1998 at 8:30 a.m.  (Pacific
daylight time) for the following purposes:

      1.  To  elect two Class 1 directors to the Company's Board  of
          Directors for terms expiring in 2001.
     
      2.  To consider and vote upon a proposal to amend the NeoPath,
          Inc. 1989 Restated Stock Option Plan (the "1989 Plan")  to
          authorize the issuance of an additional 720,000 shares  of
          Common  Stock upon exercise of options granted  under  the
          1989 Plan.
     
      3.  To  transact  such  other business as  may  properly  come
          before   the   Annual  Meeting  or  any  adjournments   or
          postponements thereof.

      The record date for the Annual Meeting was March 25, 1998.  Only
shareholders  of  record at the close of business  on  that  date  are
entitled  to  notice of, and to vote at, the Annual  Meeting  and  any
adjournments or postponements thereof.

      The affirmative vote of the holders of a plurality of the shares
of  Common Stock present, in person or by proxy, at the Annual Meeting
is  required for the election of directors.  The affirmative  vote  of
the  holders of shares representing a majority of the shares of Common
stock present, in person or by proxy, and entitled to vote thereon  at
the  Annual Meeting is required to approve the amendment of  the  1989
Plan.

                                    By Order of the Board of Directors



                                    Alan C. Nelson
                                    President and
                                    Chief Executive Officer

Redmond, Washington
April 14, 1998
                                   
     WHETHER OR NOT YOU PLAN TO ATTEND THE ANNUAL MEETING, PLEASE SIGN
AND DATE THE ENCLOSED PROXY CARD AND RETURN IT AS PROMPTLY AS POSSIBLE
IN  THE  ENCLOSED  STAMPED AND ADDRESSED ENVELOPE IN  ORDER  THAT  THE
PRESENCE  OF  A QUORUM MAY BE ASSURED.  YOUR STOCK WILL  BE  VOTED  IN
ACCORDANCE  WITH THE INSTRUCTIONS YOU HAVE GIVEN IN THE  PROXY.   YOUR
PROXY  MAY  BE REVOKED AT ANY TIME BEFORE IT IS VOTED BY  SIGNING  AND
RETURNING  A  LATER-DATED PROXY WITH RESPECT TO THE  SAME  SHARES,  BY
FILING  WITH THE SECRETARY OF THE COMPANY A WRITTEN REVOCATION BEARING
A  LATER  DATE,  OR BY ATTENDING AND VOTING IN PERSON  AT  THE  ANNUAL
MEETING.
                                   
<PAGE>

                        [LOGO OF NEOPATH, INC.]
                                   
                        8271 - 154th Avenue NE
                      Redmond, Washington  98052
                                   
                            PROXY STATEMENT
                                  FOR
                    ANNUAL MEETING OF SHAREHOLDERS
                        TO BE HELD MAY 21, 1998

General

     This  Proxy  Statement is furnished by the Board of Directors  of
NeoPath,  Inc.,  a  Washington corporation  (the  "Company"),  to  the
holders  of Common Stock, $.01 par value, of the Company (the  "Common
Stock"),  in connection with the solicitation of proxies by the  Board
of  Directors for use at the 1998 Annual Meeting of Shareholders  (the
"Annual Meeting"), to be held at 8:30 a.m. (Pacific daylight time)  on
Thursday,  May  21,  1998, at The Hyatt Regency Bellevue  at  Bellevue
Place,  900  Bellevue  Way  NE,  Bellevue,  Washington,  and  at   any
adjournments or postponements thereof.

     This  Proxy Statement and the enclosed proxy card are first being
mailed to shareholders on or about April 14, 1998.

Revocability of Proxies

     A  proxy  delivered pursuant to this solicitation is revocable at
the  option  of the person giving the same at any time  before  it  is
exercised.   A  proxy  may  be  revoked, prior  to  its  exercise,  by
executing and delivering a later-dated proxy card with respect to  the
same  shares prior to the Annual Meeting, by delivering written notice
of revocation to the Secretary of the Company at any time prior to the
vote,  or  attending and voting at the Annual Meeting.  Attendance  at
the Annual Meeting, in and of itself, will not constitute a revocation
of  a proxy.  Unless previously revoked, the shares represented by the
enclosed  proxy  will  be voted in accordance with  the  shareholder's
directions  if the proxy is duly executed and returned  prior  to  the
Annual  Meeting.  If no directions are specified, the shares  will  be
voted  "FOR,"  (i)  the election of the Directors recommended  by  the
Board of Directors, (ii) the approval to amend the NeoPath, Inc.  1989
Restated Stock Option Plan (the "1989 Plan") to authorize the issuance
of  an  additional 720,000 shares of Common Stock issuable  under  the
1989  Plan, and (iii) in accordance with the discretion of  the  named
proxies, on other matters properly brought before the Annual Meeting.

Record Date; Shares Entitled to Vote; Vote Required

     The  close of business on March 25, 1998 (the "Record Date")  has
been fixed as the record date for determining the holders of shares of
Common  Stock who are entitled to notice of and to vote at the  Annual
Meeting.   As  of  the  Record Date, there were 14,469,192  shares  of
Common  Stock outstanding and entitled to vote.  The holders of record
on  the Record Date of shares of Common Stock are entitled to one vote
per  share  of Common Stock.  The presence, in person or by proxy,  of
the  holders of shares representing a majority of the voting power  of
the shares of Common Stock entitled to vote is necessary to constitute
a quorum for the transaction of business at the Annual Meeting.

     Under  Washinton law and the Company's Articles of Incorporation,
if a quorum is present at the Annual Meeting, (a) the two nominees for
election  as directors who receive the greatest number of  votes  cast
for  the  election of directors at the Annual Meeting  by  the  shares
present  in  person or represented by proxy at the Annual Meeting  and
entitled  to vote shall be elected directors, and (b) the proposal  to
amend the 1989 Plan will be approved if the votes cast in favor of the
proposal  by the shares present in person or represented by  proxy  at
the  Annual Meeting and entitled to vote exceed the votes cast against
the  proposal.   Abstention from voting will have  no  effect  on  the
election  of  directors or the approval to amend the 1989  Plan  since
they  will  not  represent votes cast at the Annual  Meeting  for  the
purposes  of electing directors and approval to amend the  1989  Plan.
Because brokers have discretion to vote shares of Common Stock held on
behalf  of beneficial owners if no instructions for voting such shares
are received as to the matters to be voted upon at the Annual Meeting,
there will be no "broker nonvotes."

Page 1
<PAGE>

Solicitation of Proxies

     The  accompanying Proxy is being solicited by and on behalf of the
Company's Board of Directors.  The expense of preparing, printing,  and
mailing  this Proxy Statement and the proxies solicited hereby will  be
borne by the Company.  In addition to the use of the mails, proxies may
be  solicited  by  directors,  officers, and  other  employees  of  the
Company,  without additional remuneration, in person, or by  telephone,
or  facsimile  transmission.  The Company will also  request  brokerage
firms,  bank  nominees, custodians, and fiduciaries  to  forward  proxy
materials  to  the beneficial owners of Common Stock as of  the  Record
Date  and  will  provide reimbursement for the cost of  forwarding  the
proxy   materials   in  accordance  with  customary   practice.    Your
cooperation in promptly signing and returning the enclosed  proxy  card
will help avoid additional expense.


         1.  ELECTION OF DIRECTORS AND MANAGEMENT INFORMATION

     The  Company's Articles of Incorporation provide that the members
of  the  Board of Directors be divided into three classes,  as  nearly
equal  as possible.  Each class is elected for a three-year term.   At
each  annual  meeting  of shareholders, one  class  of  the  Board  of
Directors is elected for a three-year term and directors in the  other
classes  remain  in  office  until their respective  three-year  terms
expire.  The Company's Board of Directors presently consists of  seven
members,  with  two members in Classes 1 and 2, and three  members  in
Class  3.  At the expiration of each class' term, continuing directors
are  to  be elected to serve for a term of three years or until  their
respective  successors  have  been elected  and  qualified.   Alan  D.
Frazier, whose term expires in 1998, is leaving the Board of Directors
effective May 21, 1998.

     The two nominees, Alan C. Nelson, Ph.D., and Thomas A. Bonfiglio,
M.D. comprise the class to be elected at the Annual Meeting for three-
year  terms  expiring  at the 2001 annual meeting.   Unless  otherwise
directed, the persons named in the proxy intend to cast all proxies in
favor  of Alan C. Nelson and Thomas A. Bonfiglio to serve as directors
of  the  Company.  It is intended that votes will be cast pursuant  to
the  accompanying  proxy  for the election of  these  nominees  unless
contrary  instructions  are received.  If any  nominee  should  become
unavailable for any reason, it is intended that votes will be cast for
a   substitute  nominee  as  designated  by  the  Company's  Board  of
Directors.   The  Board  of Directors has no reason  to  believe  that
either of the nominees named will be unable to serve if elected.

Information About the Director Nominees

     Alan C. Nelson, Ph.D., (age 48), the Company's founder, President
and  Chief Executive Officer, has been a Director since May 1989.   He
was  the  Company's Chairman of the Board from March 1991  until  June
1994,  when  he  became President and Chief Executive  Officer.   From
September 1986 to September 1992, he was an associate professor at the
Center  for Bioengineering and an adjunct professor in the Departments
of  Pathology, Radiology, and Electrical Engineering at the University
of  Washington, where he directed that university's Center for Imaging
Systems  Optimization from 1990 to 1991.  Since 1991, Dr.  Nelson  has
held an affiliate professorship with the Center for Bioengineering  at
the University of Washington.

     Thomas  A.  Bonfiglio, M.D., (age 55) serves as Senior  Attending
Pathologist  and  Director  of Cytology at  The  Genesee  Hospital  in
Rochester,  New York.  Dr. Bonfiglio is also a Clinical  Professor  at
the  University of Rochester's Department of Pathology and  Laboratory
Medicine,  where  he has maintained various academic  positions  since
1971.   Since  1969,  Dr.  Bonfiglio has held pathology  positions  at
various  hospitals, most recently as Pathologist in  Chief  at  Strong
Memorial  Hospital from 1989 to 1997.  He is a past president  of  the
American Society of Clinical Pathologists and the American Society  of
Cytopathology and has authored numerous medical publications.

Information About Directors Whose Terms of Office Continue  After  the
Annual Meeting

  Terms expire 1999:

     David  A. Thompson,  (age 56),   has  been   a  Director  of  the 
Company  since  June  1995.    Mr.  Thompson  retired  in  June   1995  
from   Abbott   Laboratories    ("Abbott"),   a    manufacturer    and   
distributor   of   pharmaceutical  and  nutritional  products,   where 

Page 2
<PAGE>

he  served in various capacities since 1964.  From August 1983 to  July
1990,  he  was  Abbott's  Vice  President,  Diagnostic  Operations  and
President,  Diagnostics Division; from July 1990 to June 1994,  he  was
Abbott's  Senior Vice President, Diagnostic Operations  and  President,
Diagnostics Division; and from June 1994 until his retirement,  he  was
Abbott's  Senior Vice President, Strategic Improvement Processes.   Mr.
Thompson  is currently Chief Executive Officer of Diagnostic  Marketing
Strategies, a private consulting firm.  Mr. Thompson is also a director
of HYCOR Biomedical, Inc., NABI, and LifeCell Corporation.

     Gail  R.  Wilensky, Ph.D., (age 54), has been a  Director  of  the
Company  since  June 1996.  Dr. Wilensky has served as a John  M.  Olin
Senior  Fellow  of Project HOPE since January 1993, serving as a formal
and  informal  advisor  to  government  and the  private  sector.   Dr.
Wilensky  is  also currently the  chairperson for the Medicare  Payment
Advisory  Commission  where  she  advises the  United  States  Congress
regarding  Medicare and Medicaid.  During 1992 and 1993,  Dr.  Wilensky
was  Deputy Assistant to the  President for Policy Development advising
the   President,   Vice  President  and  other   senior  administration
officials  on issues related to health care  and welfare  reform.   Dr.
Wilensky  is  also  a  director  of  Advanced  Tissue  Sciences,  Inc.,
Pharmerica, Inc.,  Quest  Diagnostics Incorporated,  St. Jude  Medical,
Inc.,   Shared   Medical  Systems   Corporation,  Syncor  International
Corporation and United HealthCare Corporation.

  Terms expire 2000:

     Walter  L.  Robb,  Ph.D., (age 69), has been  a  Director  of  the
Company  since July 1993 and was elected Chairman of the Board in  June
1994.   From  1986 to 1993, when he retired, Dr. Robb was  Senior  Vice
President and Director of Corporate Research and Development of General
Electric  Corporation.  From 1973 to 1986, he was Senior Vice President
and  General  Manager  of GE Medical Systems,  a  division  of  General
Electric   Corporation.   Dr.  Robb  is  the  sole  owner  of   Vantage
Management,  Inc., a private consulting firm.  Dr.  Robb  serves  as  a
director  of  Celgene  Corp., Cree Research,  Inc.,  Marquette  Medical
Systems, Inc. and Mechanical Technology, Inc.

     Cristina  H. Kepner, (age 51), has been a Director of the Company
since  April  1994.   Ms. Kepner has been a Director,  Executive  Vice
President, and Corporate Finance Director of Invemed Associates, Inc.,
an  investment banking firm, since February 1978.  Invemed Associates,
Inc.  served as underwriter for the Company's initial public  offering
in  February  1995  and for the Company's second  public  offering  in
January 1996.  Ms. Kepner is also a director of Quipp, Inc.

     William  L.  Scott, (age 54), the  Company's Vice  President  and
Chief  Financial Officer since March 1997, has been a Director of  the
Company  since  May  1997.  Mr. Scott was Vice President  and  General
Manager   of  Boston  Scientific  Corporation's  Northwest  Technology
Center, Inc. from January 1996 through December 1996.  Prior to Boston
Scientific's  acquisition of Heart Technology,  Inc.,  Mr.  Scott  was
Heart  Technology's Vice Present, Finance and Administration and Chief
Financial Officer from January 1992 through December 1995.  Mr.  Scott
served as Vice President and Chief Financial Officer at various  other
companies, including Pentzer Corporation from 1990 through 1991,  Flow
International  from 1989 through 1990, and Physio-Control  Corporation
from 1975 through 1982.

Compensation of Directors

     Nonemployee  directors  receive $1,000 per board meeting  attended
and  $600  per committee meeting attended, plus out-of-pocket expenses.
In  addition, nonemployee directors receive an annual retainer  fee  of
$10,000,  which  is  paid in $2,500 installments at  the  end  of  each
calendar quarter.

     On June 25, 1996, the Company's shareholders approved the NeoPath,
Inc.  Stock  Option  Plan  for Nonemployee Directors,  as  amended  and
restated  on  April 26, 1996 (the "Nonemployee Directors  Plan")  which
specified  that  a  director is granted an option  to  purchase  10,000
shares of Common Stock annually during his or her term of office on the
first  business  day  following each annual  meeting  of  shareholders.
Options  granted under this Nonemployee Directors Plan  vest  in  three
equal  annual installments, beginning one year after the date of grant,
and  the  exercise  price  is equal to the fair  market  value  of  the
Company's Common Stock on the date of grant.

Page 3
<PAGE>

     On  February 27, 1997, the Board of Directors amended and restated
the   Nonemployee  Directors  Plan  such  that  the  number  of  shares
purchasable  under  options granted annually to  continuing  and  newly
appointed directors during their term in office was reduced from 10,000
to  7,000 shares of the Company's Common Stock.  Under the Amended  and
Restated  Nonemployee  Directors Plan,  such  options  are  granted  to
nonemployee  directors on the last business day prior  to  each  annual
meeting  of shareholders (excluding any director whose term expires  on
the  date  of  the  annual meeting prior to which an option  is  to  be
granted  and who has not been nominated for re-election at such  annual
meeting).  Such options vest and become exercisable in full on the  day
immediately  prior  to the annual meeting next following  the  date  of
grant (disregarding the annual meeting being held immediately after the
date  of  grant).  On May 21, 1997, all nonemployee directors  received
grants to purchase 7,000 shares of Common Stock in accordance with  the
provision of the Amended and Restated Nonemployee Directors Plan.

Information on Committees of the Board of Directors

     The Company's Board of Directors has standing Compensation, Audit
and Nominating Committees.  Each of these committees is responsible to
the  full Board of Directors, and its activities are therefore subject
to  approval of the Board of Directors.  The members of each Committee
and the functions performed thereby are described below:

     Compensation Committee.  During 1997,  the Compensation Committee
was  comprised  of Mr. Thompson, Mr. Frazier, and Dr.  Wilensky.   The
Compensation  Committee  establishes salaries,  incentives  and  other
forms  of  compensation  for directors and officers  of  the  Company,
administers  the  1989 Plan, and recommends policies relating  to  the
Company's benefit plans.  The Compensation Committee met five times in
1997.

     Audit Committee.  During 1997, the Audit Committee was comprised
of  Mr. Frazier, who was a member throughout the year, and Ms. Kepner,
who  became a member effective May 22, 1997.  C. Richard Kramlich, who
left  the  Board of Directors effective May 22, 1997, was a member  of
the  Audit  Committee  in  1997 prior to  his  departure.   The  Audit
Committee   oversees  the  engagement  of  the  Company's  independent
auditors  and,  together  with  the  Company's  independent  auditors,
reviews   the  Company's  accounting  practices,  internal  accounting
controls  and financial results.  The Audit Committee met three  times
in 1997.

     Nominating Committee.  During 1997, the Nominating Committee  was
comprised of Dr. Robb and Ms. Kepner.  The Nominating Committee  makes
recommendations  to  the  Board  of Directors  concerning  prospective
candidates  to  fill  vacancies  on  the  Board  of  Directors.    The
Nominating  Committee met one time in 1997.  The Nominating  Committee
will consider the names and qualifications of candidates for the Board
of   Directors  submitted  by  shareholders  in  accordance  with  the
procedures  referred to in "Proposals of Shareholders" in  this  Proxy
Statement.

     During  1997  there were five meetings of the Board of Directors,
one of which was held telephonically.  Each director attended at least
75  percent of all board meetings and meetings of committees on  which
they  served except Dr. Wilensky, who attended 60 percent of the board
meetings and Compensation Committee meetings.

Page 4
<PAGE>

Executive Officers

     The executive officers of the Company, and their ages as of March
15, 1998, are as follows:

     Name                  Age   Position
     ____                  ___   ________
                          
     Alan C. Nelson        48    President and Chief Executive Officer and
                                 Director
     William L. Scott      54    Vice President and Chief Financial
                                 Officer and Director
     Shih-Jong James Lee   42    Vice President and Chief Technical
                                 Officer
     David H. Robison      48    Vice President, Operations
     Larry A. Nelson       52    Vice President, Intellectual Property and
                                 New Business Development
     Kumar K. Shahani      43    Vice President, Marketing and Business
                                 Assessment
     Robert C. Bateman     35    Corporate Controller and Treasurer
     Volker R. Kettering   48    Former Vice President, Sales
     
     
     For  information regarding Alan C. Nelson see "--Information About
the Director Nominees."
     
     For  information  regarding William L.  Scott  see  "--Information
About Directors Whose Terms of Office Continue After Annual Meeting."
     
     Shih-Jong  James  Lee, Ph.D., Vice President and  Chief  Technical
Officer, joined NeoPath in March 1989.  Dr. Lee served as the Company's
Chief   Scientist  beginning  March  1993  and  Vice  President,  Chief
Scientist  in February 1995.  In 1997, Dr. Lee was named Vice President
and  Chief Technical Officer.  Dr. Lee was Principal Engineer  for  the
High  Technology Center of the Boeing Company from 1986  to  1989,  and
founded its Image Analysis Group.  He currently serves on the Editorial
Board of the Pattern Recognition Journal.
     
     David  H.  Robison, Vice President, Operations, joined NeoPath  in
May 1996.  Prior to joining NeoPath, Mr. Robison was employed by Abbott
Laboratories in various positions from February 1978 through May  1996.
From  February  1995  to  May  1996,  Mr.  Robison  was  Research   and
Development  Director for Abbott's Diagnostic Division,  and  from  May
1990 to February 1995 he was Director, Customer Satisfaction.
     
     Larry  A.  Nelson, Vice President, Intellectual Property  and  New
Business  Development, joined NeoPath in October 1992.  Mr. Nelson  was
NeoPath's Vice President, Research and Engineering until 1997, when  he
was  named  Vice  President,  Intellectual Property  and  New  Business
Development.   Mr.  Nelson was employed at Honeywell,  Inc.  as  Senior
Fellow  from  1990 to 1992, and as Senior Staff Engineer from  1986  to
1990.
     
     Kumar   K.   Shahani,  Vice  President,  Marketing  and   Business
Assessment,  joined  NeoPath in December  1996.   From  April  1995  to
November  1996,  Mr.  Shahani  was  Director  of  Marketing  at   Ostex
International, a biotechnology company.  Mr. Shahani was Global  Market
Development  Manager at Puritan-Bennett Corporation, a  medical  device
manufacturer, from January 1989 to April 1995.
     
     Robert  C.  Bateman,  Corporate Controller and  Treasurer,  joined
NeoPath in March 1996.  Mr. Bateman joined the Company as its Corporate
Controller and was also named Corporate Secretary in May 1996.  In  May
1997,   Mr.   Bateman  was  named  Treasurer  and  Assistant  Corporate
Secretary.   From May 1987 to March 1996, Mr. Bateman was  employed  by
Ernst  &  Young LLP and served in various capacities, most recently  as
Senior  Manager.  Mr. Bateman currently serves as chairman of the  High
Technology Industries Committee of the Washington Society of  Certified
Public Accountants.
     
     Volker R. Kettering served as Vice President, Sales from June 1995
through  January  1998.  Mr. Kettering was employed at Siemens  Medical
Systems,  Inc.,  an electronics manufacturer, from June  1973  to  June
1995,  most recently as its Vice President of the Western Zone  of  the
Imaging  Systems Group from March 1995 to June 1995 and,  from  October
1986  to  March 1995, as its District Manager of the Pacific  Northwest
Region.
     
Page 5
<PAGE>

Section 16(a) Beneficial Ownership Reporting Compliance

     Section  16(a)  of   the  Exchange  Act  requires  the  Company's
directors and executive officers, and persons who own more than 10% of
the  Common Stock, to file with the Securities and Exchange Commission
(the  "SEC")  initial reports of beneficial ownership ("Form  3")  and
reports  of changes in beneficial ownership of Common Stock and  other
equity securities of the Company ("Form 4").  Officers, directors, and
greater  than  10%  shareholders of the Company are  required  by  SEC
regulations  to  furnish to the Company copies of  all  Section  16(a)
reports that they file.  To the best of the Company's knowledge, based
solely  on  a  review of the copies of such reports furnished  to  the
Company  and  written  representations  that  no  other  reports  were
required,  all  Section 16(a) filing requirements  applicable  to  its
officers,  directors,  and  greater than 10%  beneficial  owners  were
complied with during 1997.

Page 6
<PAGE>

Executive Compensation

  Summary of Compensation

     The following table sets forth certain information with respect to
compensation paid by the Company for the fiscal year ended December 31,
1997  and  for  the two prior fiscal years to (i) the  Company's  Chief
Executive  Officer  and  (ii)  the Company's  four  other  most  highly
compensated executive officers whose salary and bonus exceeded $100,000
for  services performed during the fiscal year ended December 31,  1997
(collectively, the "Named Executive Officers").

                      Summary Compensation Table
<TABLE>
<CAPTION>

                                                                              Long-Term
                                                                            Compensation
                                    Annual Compensation                        Awards
                               _________________________________________      __________      
                                                                              Securities
Name and                                                 Other Annual         Underlying
Principal Position      Year   Salary($)  Bonus($)(4)  Compensation($)(5)     Options(#)
__________________      ____   _________  ___________  __________________     __________
<S>                     <C>    <C>         <C>              <C>                <C>
Alan C. Nelson(1)       1997   $ 300,014   $      --        $  1,400            62,160
  President and Chief   1996   $ 257,022   $ 102,150        $    750           100,000
  Executive Officer     1995   $ 156,683   $ 100,000        $    750            50,000
                                                     
Shih-Jong James Lee     1997   $ 182,000   $      --        $  8,836            26,000
  Vice President and    1996   $ 166,985   $  54,146        $  1,500            27,793
  Chief Technical       1995   $ 120,231   $  21,870        $  6,750            20,000
  Officer          
                                                     
David H. Robison(2)     1997   $ 155,616   $      --        $     --            17,680
  Vice President,       1996   $  87,692   $  28,652        $     --            50,000              
  Operations
                                                     
Larry A. Nelson(1)      1997   $ 145,616   $      --        $  1,400            16,570
  Vice President,       1996   $ 139,365   $  38,744        $     --            41,250
  Intellectual          1995   $ 117,673   $  21,405        $     --                --
  Property and New
  Business Development
                                                     
Volker R. Kettering(3)  1997   $ 145,950   $      --        $     --            16,060
  Former Vice           1996   $ 144,750   $  43,858        $     --            15,000
  President, Sales      1995   $  55,385   $  59,642        $     --            35,000
</TABLE>
____________________
(1)  Alan C. Nelson and Larry A. Nelson are not related.
(2)  David H. Robison joined the Company as Vice President, Operations
     in May 1996.
(3)  Volker R. Kettering, the Company's former Vice President, Sales, joined  
     the Company in June 1995.  Mr. Kettering left the Company in January 1998.
(4)  Unless otherwise noted, bonuses were earned by achievement of
     specified corporate goals approved by the Compensation Committee of the
     Board of Directors.  Payment of such bonuses was made within 60 days
     following the respective year end.
(5)  Represents compensation paid in connection with the filing of patent 
     applications.
 
 Page 7
 <PAGE>
 
 Grants of Stock Options

     The following table sets forth certain information regarding stock
options granted during the fiscal year ended December 31, 1997  to  the
Named Executive Officers.

                   Option Grants in Last Fiscal Year

                         Individual Grants                       
___________________________________________________________________   
<TABLE>
<CAPTION>
                                                                     
                                                                     Potential Realizable   
                                                                            Value at
                                                                         Assumed Annual
                                  Percent of                                Rates of
                   Number of     Total Options                             Stock Price          
                   Securities     Granted to                            Appreciation for
                   Underlying      Employees   Exercise                  Option Term(2)
                    Options           in        Price    Expiration    __________________
Name              Granted(#)(1)   Fiscal Year   ($/Sh)      Date        5%($)      10%($)
_______           _____________   ___________  ________   _________    ______      ______
<S>                   <C>            <C>        <C>        <C>      <C>        <C>
Alan C. Nelson        62,160         7.7%       $18.00     5/22/07  $ 703,658  $ 1,783,207
Shih-Jong James Lee   26,000         3.2         18.00     5/22/07    294,323      745,871
David H. Robison      17,680         2.2         18.00     5/22/07    200,139      507,193
Larry A. Nelson       16,570         2.1         18.00     5/22/07    187,574      475,350
Volker R. Kettering   16,060         2.0         18.00     5/22/07    181,801      460,719
</TABLE>
__________
(1)  One-quarter of the options vest on each anniversary of the
     date of grant.  All such stock options had an exercise price per
     share equal to the per share market price of the Common Stock on
     the date of grant.
(2)  Based on the exercise price per share on the date of grant.  There  
     can be no assurance that the actual value per share realized
     by a Named Executive Officer will approximate the potential
     realizable values set forth in the table.


  Exercise of Stock Options and Year-End Values

     The following table sets forth certain information regarding stock
options  exercised during the fiscal year ended December 31,  1997  and
options held at December 31, 1997 by the Named Executive Officers.

                 Aggregated Option Exercises in Last Fiscal Year 
                           and Year-End Option Values
<TABLE>
<CAPTION>
                                                                     
                                                       
                                                                        
                                                         Number of         
                                                   Securities Underlying        Value of Unexercised
                                                    Unexcercised Options        In-the-Money Options
                     Shares                        at Fiscal Year-End(#)       at Fiscal Year-End($)(2)
                   Acquired on       Value       __________________________  __________________________
Name               Exercise(#)   Realized($)(1)  Exercisable  Unexercisable  Exercisable  Unexercisable
_________            _______     ______________  ___________  _____________  ___________  _____________
<S>                  <C>         <C>               <C>           <C>         <C>             <C>                               
Alan C. Nelson        36,000       $ 439,680       164,233       141,328     $ 990,051       $     --               
Shih-Jong James Lee   21,045         322,325        28,811        49,377        43,011          8,850
David H. Robison          --              --        19,790        47,890            --             --
Larry A. Nelson       16,500         281,325        16,328        41,492            --             --
Volker R. Kettering       --              --        27,812        38,248            --             --
</TABLE>
__________
(1)  Based on the closing price of the Company's Common Stock on
     the date of exercise.
(2)  Based on the closing price of the Company's Common Stock on
     December 31, 1997 of $13.00 per share as reported by The Nasdaq
     Stock Market.

Page 8
<PAGE>

Compensation Committee Interlocks and Insider Participation

     During  1997,  the Compensation Committee was comprised of Messrs.
Frazier and Thompson and Dr. Wilensky.  Mr. Frazier is an affiliate  of
Frazier & Company, L.P., and Frazier Healthcare Investments, L.P.   Mr.
Frazier's  affiliates  invested in certain  of  the  Company's  private
financings since January 1, 1992.

Compensation Committee Report on Executive Compensation

     The  Compensation   Committee   of  the  Board  of  Directors  is
responsible  for  establishing  the  compensation  for  the  Company's
executive   officers  and  making  recommendations   concerning   such
compensation to the Board of Directors.  In addition, the Compensation
Committee  is  responsible  for  administering  the  1989  Plan.   The
Compensation  Committee is composed of nonemployee directors.   During
1997, the Compensation Committee was comprised of Messrs. Frazier  and
Thompson and Dr. Wilensky.

     In  1996,  the  Compensation  Committee  engaged  a  compensation
consulting  firm  to  review the Company's  compensation  program  for
officers.   The purpose of the study was to ensure that the  Company's
compensation  program  is competitive and that it  supports  NeoPath's
strategies  and  objectives.   The  study  continues  to  serve  as  a
guideline for determining the type and amount of officer compensation.
The   Committee  intends  to  provide  overall  compensation  to  each
executive at the 50th percentile of competitive survey data;  this  is
accomplished   through targeting executive salaries  at  five  percent
below  the  50th  percentile and targeting annual incentives  at  five
percent above the 50th percentile of surveyed competitive data.

     The  underlying objectives of the Company's compensation strategy
are  to  attract  and  retain the best possible executive  talent,  to
motivate those executives to achieve optimum operating performance for
the  Company,  to  link  executive and shareholder  interests  through
equity-based  plans,  and  to  provide  a  compensation  package  that
recognizes  individual  contributions  as  well  as  overall  business
results.   The  Compensation  Committee  believes  that  the   overall
compensation  philosophy  should  be  to  allow  for  total  executive
compensation  in  the upper quartiles of the competitive  survey  data
described  below  for  exceptional performance in achieving  corporate
goals, and that compensation in the lower quartiles should be used, as
appropriate, for less-than-expected achievement of goals.   There  are
three  components  to  the Company's executive  compensation  program:
base  salary, incentive (bonus) payments, and long-term incentives  in
the form of stock options.

     Base  Salary.  Base  salary for each executive officer  is  based
primarily  on  competitive  survey data for  comparable  positions  at
medical   products,  biotechnology  and  high  technology   companies,
supplemented by an assessment of each officer's sustained performance,
advancement  potential,  experience,  responsibility,  and  scope  and
complexity  of  management  position.  The companies  in  this  survey
include  some  but not all of the companies in the Hambrecht  &  Quist
Healthcare  Section  Excluding Biotech Index  included  in  the  Stock
Performance Graph.

     Annual  Incentives.  The  Compensation  Committee  believes  that
executives'  performance  is  most  appropriately  measured  based  on
progress  toward  achieving operating goals  that  are  formulated  to
promote  advancement  of key aspects of the Company's  business.   The
Board  of  Directors  and  Compensation Committee  approved  NeoPath's
corporate  goals  for 1997 and approved management's establishment  of
specified  minimum  financial goals for officers to  receive  bonuses.
The  corporate goals included achieving defined financial performance,
filing an amendment to the Pre-Market Approval Supplement to the  U.S.
Food  and  Drug  Administration for use of the  AutoPap  System  as  a
Primary  Pap  Smear Screening System, and developing specific  product
enhancements.  The defined minimum 1997 financial goals were not  met;
therefore,  no  bonuses  were  paid  to  officers.   The  Compensation
Committee  intends  to continue to base future annual  incentives  for
officers on the achievement of defined goals and milestones, with  the
range of potential awards based primarily on competitive survey data.

     Long-Term    Incentives.     The    long-term    performance-based
compensation   of   executive  officers  takes  the  form   of   option  
awards   under   the   1989   Plan.    The   Compensation     Committee 
believes   that  the   equity-based   compensation   ensures  that  the   
Company's    executive   officers   have   a   continuing   stake    in  
the  long-term  success  of  the  Company.  Since the Company's initial

Page 9
<PAGE>

public  offering, all options granted by the Company have been  granted
with an exercise price equal to or in excess of the market price of the
Company's  Common Stock.  Accordingly, stock options  will  have  value
only  if  the  Company's stock price increases.   Vesting  is  used  to
encourage employees to continue in the employ of the Company.

  1997 Compensation for the Chief Executive Officer

     In  determining  Dr.  Nelson's  salary  for  1997,  the  Committee
considered  competitive compensation data for chief executive  officers
of  similar companies within the medical device, biotechnology and high
technology industries, taking into account Dr. Nelson's experience  and
knowledge.   No  change was made to Dr. Nelson's salary  in  1997.   As
further described under "--Long-Term Incentives," long-term performance-
based compensation of executive officers takes the form of stock option
grants.  During 1997, Dr. Nelson was awarded a grant to purchase 62,160
shares  of the Company's Common Stock, with the exercise price  of  the
options equal to the market price of NeoPath's Common Stock on the date
of  grant.   The grant was based on the Committee's use of  a  formula-
based  model applied to all eligible NeoPath employees.  No  bonus  was
paid to Dr. Nelson.

  Section 162(m) Limitations on Executive Compensation

     Section 162(m)  of the Internal Revenue Code of 1986, as amended,
makes   certain  nonperformance-based  compensation   in   excess   of
$1  million  paid  to executives of public companies nondeductible  by
such  companies.  Certain performance-based compensation that has been
approved  by shareholders is not subject to the deduction limit.   The
1989  Plan is structured to qualify options granted under the plan  as
performance-based compensation under Section 162(m).  At this time, no
executive  officer of the Company has received, nor is it  anticipated
that  any  executive  officer will receive, any such  compensation  in
excess  of  this limit.  Therefore, no action was required  to  comply
with  the limit.  The Compensation Committee will continue to  monitor
the  situation and will take appropriate action if it is warranted  in
the future.

                                              Compensation Committee



                                              David A. Thompson
                                              Alan D. Frazier
                                              Gail R. Wilensky, Ph.D.

Page 10
<PAGE>

Stock Performance Graph

     The  following  graph  compares the cumulative total  shareholder
return  on the Company's Common Stock with the cumulative total return
of  The  Nasdaq  Stock  Market and the Hambrecht  &  Quist  Healthcare
Section  Excluding Biotech Index for the period beginning  on  January
26,  1995, the Company's first day of trading after its initial public
offering, and ending on December 31, 1997.

                      Comparison of Cumulative Total Return Among
                                     NeoPath, Inc.,
                              The Nasdaq Stock Market and
            Hambrecht & Quist Healthcare Section Excluding BioTechnology Index
                            (Period Ended December 31, 1997)

Measurement   
Period                                                   
(Quarterly 
from
January 26,                            The Nasdaq            Hambrecht & Quist
1995)           NeoPath, Inc.         Stock Market                 Index
______________________________________________________________________________

Jan-26-95          100.00                100.00                    100.00
Mar-31-95          122.92                108.11                    110.88
Jun-30-95          137.50                123.66                    113.90
Sep-30-95          220.83                138.56                    142.48
Dec-31-95          193.75                140.27                    158.05
Mar-31-96          193.75                146.80                    169.08
Jun-30-96          210.42                158.79                    158.91
Sep-30-96          160.42                164.44                    174.39
Dec-31-96          152.08                172.53                    175.47
Mar-31-97          114.58                163.24                    166.68
Jun-30-97          158.33                193.17                    199.54
Sep-30-97          162.50                225.84                    209.14
Dec-31-97          108.33                211.80                    209.11
       
       
       Assumes $100 invested in the Company's Common Stock, The  Nasdaq
       Stock  Market  and  the  Hambrecht  &  Quist  Healthcare Section
       Excluding  Biotech Index, with all dividends reinvested.   Stock
       performance  shown in the above chart for the  Common  Stock  is
       historical   and  not  necessarily indicative  of  future  price
       performance.

Page 11
<PAGE>

Employment  Contracts  and  Termination of  Employment  and  Change-in-
  Control Agreements

     In  December  1996, the Compensation Committee approved  a  Senior
Management   Employment  Agreement  (the  "Agreement")   for   officers
(including  the Named Executive Officers) and key management  personnel
that  provides  for  continued employment  terms  equivalent  to  those
applicable immediately prior to a change in control for the  two  years
following  a change in control.  A one-time cash payment equal  to  two
times  the executive's annual salary and bonus is immediately triggered
if,  following a change in control, employment is terminated by (i) the
employee  for  "good reason" or (ii) the employer for any reason  other
than  death, disability or for "cause."  The Agreement was approved  by
the  Company's  Board  of Directors in February  1997.   The  Committee
believes  that the Agreement enables NeoPath management to focus  their
efforts on the long-term achievement of Company goals.
     
     The  1989  Plan provides optionees with the right to exercise  all
stock  options, whether or not the vesting requirements have been  met,
immediately prior to defined changes in the Company's ownership.

Page 12
<PAGE>

Security Ownership of Certain Beneficial Owners and Management

     The  following table sets forth as of February 27, 1998, except as
otherwise  noted,  certain information with respect to  the  beneficial
ownership  of the Common Stock by (i) each person known by the  Company
to  beneficially  own  more  than 5% of the  Common  Stock,  (ii)  each
director  and  nominee  for director of the Company,  (iii)  the  Named
Executive  Officers, and (iv) all directors and executive  officers  of
the  Company  as  a group. Except as otherwise indicated,  the  Company
believes  that the beneficial owners of the Common Stock listed  below,
based  on  information furnished by such owners, have sole  voting  and
investment power with respect to such shares.

                                          Shares        Percent
                                       Beneficially       of
        Name and Address                   Owned        Class
        ________________                 ________       _____
                                                   
        Alan C. Nelson(1)                488,414        3.4%
        Shih-Jong James Lee(2)            29,150         *
        David H. Robison(3)               24,209         *
        Volker R. Kettering(4)            27,812         *
        Larry A. Nelson(5)                38,071         *
        Thomas A. Bonfiglio                   --         *
        Alan D. Frazier(6)               157,442        1.1%
        Cristina H. Kepner(7)             51,819         *
        Walter L. Robb(8)                150,427        1.0%
        William L. Scott(9)               18,750         *
        David A. Thompson(10)             18,665         *
        Gail R. Wilensky(11)               3,333         *
        Trustees of General Electric   
          Pension Trust(12)            1,526,463       10.6%        
          3033 Summer Street          
          Stamford, CT 06904-7900
        Soros Fund Management LLC,                 
        George Soros, Stanley F.        
        Druckenmiller(13)              1,307,827        9.1%
          888 Seventh Avenue, 
          33rd Floor
          New York, NY  10106
        Duquesne Capital Management,     
          LLC(13)                        157,500        1.1%
          2579 Washington Road, 
          Suite 322
          Pittburgh, PA  15241-2591
        The Capital Group Companies,               
          Inc., Capital Research                     
          and Management Company, and    
          SMALLCAP World Fund, Inc.(14)  900,000        6.2%
          333 South Hope Street
          Los Angeles, CA  90071
        The TCW Group, Inc.(15)          614,300        4.3%
          865 South Figueroa Street
          Los Angeles, CA  90017
        Robert Day(15)                   614,300        4.3%
          200 Park Avenue,          
          Suite 2200                 
          New York, NY  10166          
        T. Rowe Price Associates,        
          Inc.(16)                       946,278        6.6%
          100 E. Pratt Street                       
          Baltimore, MD  21202                      
        All Directors and Named                    
        Executive Officers as a group
          (11 persons)(17)             1,036,702        6.9%                  
______________________
* Less than 1%

Page 13
<PAGE>

(1)    Represents  309,682  outstanding shares, 176,732 shares issuable
   upon  exercise of options that are exercisable within 60  days,  and
   2,000  shares  held  by Dr. Nelson's wife for  the  benefit  of  her
   nephew.   Dr.  Nelson disclaims beneficial ownership  of  the  2,000
   shares held by his wife for the benefit of her nephew.
(2)   Includes 29,150 shares issuable upon exercise of options that are
   exercisable within 60 days.
(3)   Includes 23,957 shares issuable upon exercise of options that are
   exercisable within 60 days.
(4)    Consists  of  shares issuable upon exercise of options that  are
   exercisable within 60 days.
(5)    Includes 19,766  shares  issuable upon exercise of options  that
   are exercisable within 60 days.
(6)    Represents  1,898  outstanding shares and 11,333 shares issuable
   upon  exercise of options that are exercisable within 60  days  held
   by  Mr.  Frazier;  14,146 outstanding shares, 7,500 shares  issuable
   upon  exercise of options that are exercisable within  60  days  and
   109,455 shares issuable upon exercise of warrants held by Frazier  &
   Company   L.P.;  and  13,110  outstanding  shares  held  by  Frazier
   Management LLC.  The general partner of Frazier & Company  L.P.,  is
   Frazier Management LLC.
(7)    Includes  24,068  outstanding  shares,  11,333  shares  issuable
   upon  exercise of options that are exercisable within 60  days,  and
   16,418  shares  issuable  upon exercise  of  warrants  held  by  Ms.
   Kepner.
(8)   Includes 60,427 shares issuable upon exercise of options that are
   exercisable within 60 days.
(9)   Consists of 18,750 shares issuable upon exercise of options  that
   are exercisable within 60 days.
(10)      Includes 13,665 shares issuable upon exercise of options that
   are exercisable within 60 days.
(11)       Consists  of 3,333 shares issuable upon exercise of  options
   that are exercisable within 60 days.
(12)       Consists of shares outstanding as of December 31,  1997  per
   filing on Schedule 13G.
(13)     The following information represents ownership information  as
   of  March 5, 1998 per filing on Schedule 13G.  Soros Fund Management
   LLC  ("SFM LLC") may be deemed to be the beneficial owner of 799,000
   shares  held for the account of Quantum Partners.  Mr. Soros may  be
   deemed  the  beneficial  owner of 1,138,686  shares,  consisting  of
   799,000  shares  held  for  the  account  of  Quantum  Partners  and
   339,686  shares  held for the account of the Open Society  Institute
   ("OSI").   Mr. Druckenmiller may be deemed the beneficial  owner  of
   968,141  shares, consisting of 799,000 shares held for  the  account
   of  Quantum  Partners, 157,500 shares held for the accounts  of  the
   Duquesne  LLC  Clients, and 11,641 shares held for  the  account  of
   Druckenmiller  Foundation ("DF").  Duquesne LLC may  be  deemed  the
   beneficial owner of the 157,500 shares held for the accounts of  the
   Duquesne  LLC  Clients.   SFM  LLC  expressly  disclaims  beneficial
   ownership  of any shares held for the accounts of OSI,  DF  and  the
   Duquesne  LLC  clients.   Mr. Soros expressly  disclaims  beneficial
   ownership  of  any  shares  held for the  accounts  of  DF  and  the
   Duquesne   LLC  clients.   Mr.  Druckenmiller  expressly   disclaims
   benefical  ownership  of any shares held for  the  account  of  OSI.
   Duquesne LLC expressly disclaims beneficial ownership of any  shares
   held for the accounts of Quantum Partners, OSI and DF.
(14)     Represents ownership information as of December  31,  1997  as
   disclosed  on  Schedule  13G.  SMALLCAP  World  Fund,  Inc.  is  the
   beneficial  owner of the 900,000 shares.  Each of The Capital  Group
   Companies, Inc. and Capital Research and Management Company  may  be
   deemed  to  have  beneficial ownership of the  900,000  shares,  but
   specifically disclaim beneficial ownership.
(15)     Represents outstanding shares held by The TCW Group, Inc.  and
   Robert  Day,  an  individual who may be deemed to  control  The  TCW
   Group,  Inc.; outstanding shares as of December 31, 1997 per  filing
   on Schedule 13G.
(16)     The  outstanding shares are as of December 31, 1997 per filing
   on  Schedule 13G.  These securities are owned by various  individual
   and  institutional  investors which T. Rowe Price  Associates,  Inc.
   (Price  Associates)  serves  as investment  advisor  with  power  to
   direct  investments and/or sole power to vote the  securities.   For
   purposes  of  the reporting requirements of the Securities  Exchange
   Act of 1934, Price Associates is deemed to be a beneficial owner  of
   such  securities;  however,  Price  Associates  expressly  disclaims
   beneficial ownership.
(17) Includes 403,758 shares issuable upon exercise of options that are
   exercisable  within  60  days  and  125,873  shares  issuable   upon
   exercise of warrants.
                                   
  2.   PROPOSED AMENDMENT OF NEOPATH, INC. 1989 RESTATED 
                        STOCK OPTION PLAN

     The  Company's  1989   Plan  provides  a  means  whereby  selected
employees,  directors,  officers,  agents,  consultants,  advisors  and
independent  contractors of the Company may be granted incentive  stock
options  ("ISOs")  or nonqualified stock options ("NSOs")  to  purchase
shares  of  Common Stock.  A copy of the 1989 Plan, as proposed  to  be
amended,  is  attached  to this Proxy Statement  as  Appendix  A.   The
following description of the 1989 Plan is a summary and is not intended
to be fully descriptive.  See Appendix A for more detailed information.
Approximately 175 persons are eligible for participation  in  the  1989
Plan.   Currently, subject to adjustment required in the event  of  any
recapitalization  of  the Company, the aggregate number  of  shares  of
Common  Stock  that may be issued upon exercise of all options  granted
under  the  1989 Plan may not exceed 2,750,000.  On February 26,  1998,
the  Board  approved  an amendment to the 1989 Plan  that,  subject  to
shareholder approval, would authorize an additional 720,000  shares  to
be  available for option grants under the 1989 Plan.  As of the date of
this proxy statement, approximately 120,000 shares remain available for
future  grant  under the 1989 Plan (exclusive of the  proposed  720,000
share increase).

Page 14
<PAGE>

     The Board of Directors believes that the additional options would,
among  other  things,  promote the interests of  the  Company  and  its
shareholders  by  assisting  the Company in attracting,  retaining  and
stimulating the performance of officers and key employees.   The  Board
believes  that  the existing options have contributed substantially  to
the successful achievement of these objectives.

     The  Compensation Committee of the Board of Directors is currently
the administrator of the 1989 Plan (the "Plan Administrator").  Subject
to  the  terms of the 1989 Plan, the Plan Administrator determines  the
terms  and conditions of options granted under the 1989 Plan, including
the exercise price.  The 1989 Plan provides that the Plan Administrator
must  establish an exercise price for ISOs that is not  less  than  the
fair market value per share at the date of grant.  Each ISO must expire
within 10 years of the date of grant.  However, if ISOs are granted  to
persons  owning more than 10% of the Company's voting stock,  the  1989
Plan  provides that the exercise price shall not be less than  110%  of
the  fair market value per share at the date of grant and that the term
of the ISOs shall not exceed five years.  NSOs expire 10 years from the
date  of  grant.   Unless otherwise provided by the Plan Administrator,
one-quarter of the options vest on the first anniversary of the day  of
grant  (for options granted to new employees, the first vesting  period
is  from grant date to one year after hire date) and the remainder vest
in equal annual installments at the end of the three succeeding years.

     No option may be transferred by the optionee other than by will or
the laws of dissent or distribution.  Notwithstanding the foregoing, to
the  extent permitted by Section 422 of the Internal Revenue Code,  the
Plan  Administrator may permit an Optionee to (i) during the Optionee's
lifetime,  designate  a person who may exercise the  option  after  the
Optionee's  death by giving written notice of such designation  to  the
Company  or  (ii)  transfer the option and the  rights  and  privileges
conferred  hereby; provided, however, that any option  so  assigned  or
transferred  shall  be  subject to all the same  terms  and  conditions
contained  in  the instrument evidencing the award.  An optionee  whose
relationship with the Company or any related corporation ceases for any
reason  (other  than termination for cause, death or total  disability)
may   exercise  options  in  the  three-month  period  following   such
cessation,  (unless such options terminate or expire  sooner  by  their
terms),  or in such longer period determined by the Plan Administrator.
If the optionee is terminated for cause, the options terminate upon the
Company's  discovery of such cause.  If the optionee  dies  or  becomes
totally  disabled,  options  vested at  the  date  of  death  or  total
disability  may  be  exercised prior to the  earlier  of  the  options'
specified  expiration date or one year from the date of the  optionee's
death or disability.

     Unexercised options granted under the 1989 Plan terminate upon the
occurrence of certain events, including mergers (other than a merger of
the  Company in which the holders of shares of Common Stock immediately
before  the merger have the same proportionate ownership of  shares  of
Common  Stock  in  the  surviving  corporation  immediately  after  the
merger).  In such event, the optionee has the right immediately  before
a  merger to exercise the optionee's option in whole or in part whether
or not the vesting requirements have been satisfied.

Federal Income Tax Consequences

     The  following  discussion summarizes the material federal  income
tax consequences of participation in the 1989 Plan.  The discussion  is
general  in  nature  and does not address issues  related  to  the  tax
circumstances of any particular optionee.  The discussion is  based  on
federal income tax laws in effect on the date hereof and is, therefore,
subject  to  possible future changes in law.  The discussion  does  not
address state, local or foreign consequences.

     There  are no tax consequences to the Company or the optionee upon
the  grant of an NSO under the 1989 Plan.  Upon exercise of an NSO, the
optionee recognizes ordinary income equal to the difference between the
exercise price of the shares and the fair market value of the shares on
the date of exercise.  The Company is entitled to a tax deduction equal
to  the  income recognized by the optionee, provided that the deduction
is not otherwise disallowed by the Internal Revenue Code.

     Upon   grant   or   exercise   of   an   ISO,  an   optionee  does 
not   recognize   income,   except   that   the   excess  of  the  fair 
market   value   of   the   shares   at   the   time  of exercise (with 
adjustments  in certain  circumstances)  over   the  option  price will   
be alternative minimum taxable income for  purposes  of calculating the 
optionee's  alternative  minimum  tax, if any.  If an optionee does not

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make a "disqualifying disposition" (defined below) of an ISO, the gain,
if  any,  upon  a  subsequent sale (i.e., the excess  of  the  proceeds
received  over the option price) will be a long-term capital  gain  for
income tax purposes.

     For   shares  acquired   through   the  exercise  of  an  ISO,   a
"disqualifying disposition" is a transfer of the shares (i) within  two
years  after  the grant of the ISO or (ii) within one  year  after  the
transfer  of the shares to the optionee pursuant to the ISO's exercise.
If  the  optionee  makes  a  disqualifying  disposition,  the  optionee
generally  will  recognize  income in the  year  of  the  disqualifying
disposition equal to the excess of the amount received for  the  shares
over the option price. If, however, the optionee sells the shares to an
unrelated party at a price that is below the fair market value  of  the
shares  at  the  time  the  ISO  was  exercised,  and  the  sale  is  a
disqualifying  disposition,  the amount  of  ordinary  income  will  be
limited  to  the  amount realized on the sale over  the  option  price.
While  the  position of the Internal Revenue Service on this  issue  is
presently  unclear, any ordinary income recognized on  a  disqualifying
disposition  of  an  option  may  be  subject  to  payroll  taxes   and
withholding.

     The Company is entitled to a deduction with respect to an ISO only
if  a  disqualifying disposition occurs.  In that event, the  deduction
would  be  equal  to  the ordinary income, if any,  recognized  by  the
optionee upon disposition of the shares, provided that the deduction is
not otherwise disallowed under the Internal Revenue Code.

New Plan Benefits

     Since  awards  under   the  1989 Plan  are  discretionary,  awards
thereunder  for the current fiscal year are not presently determinable.
During 1997, options to purchase an aggregate of 138,470 shares  at  an
average exercise price of $18.00 per share were granted under the  1989
Plan  to  the Named Executive Officers of the Company as a  group,  and
options  to  purchase  an aggregate of 668,855  shares  at  an  average
exercise  price of $16.12 per share were granted to all other optionees
of  the  Company  as  a group (including officers  who  are  not  Named
Executive  Officers).   Options granted during 1997  to  the  Company's
Named  Executive  Officers for whom compensation is  reported  in  this
Proxy Statement are set forth under "Executive Compensation--Grants  of
Stock Options."

     On  February 27, 1998, the last reported sales price of the Common
Stock as reported on the Nasdaq National Market was $13.0625 per share.

     The  Board of Directors recommends a vote FOR the amendment to the
1989 Stock Option Plan.
     
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                         INDEPENDENT AUDITORS
                                   
     Representatives of Ernst & Young LLP,  the Company's  independent
public accountants, will  be  present  at the  Annual Meeting and will
have an opportunity to make a statement and to  respond to appropriate
questions from shareholders.
                                   
                       PROPOSALS OF SHAREHOLDERS

     Shareholder  proposals  to be presented  at  the  Company's  1999
Annual  Meeting  of Shareholders and included in the  Company's  Proxy
Statement relating to such meeting must be received by the Company  no
later  than  December 15, 1998.  Such proposals should be directed  to
the  Corporate  Secretary  of the Company, 8271  -  154th  Avenue  NE,
Redmond, Washington  98052.

                            OTHER BUSINESS

     It  is  not intended by the Board of Directors to bring any other
business  before the meeting, and so far as is known to the Board,  no
matters  are  to be brought before the meeting except as specified  in
the  notice  of the meeting.  However, as to any other business  which
may properly come before the meeting, it is intended that proxies,  in
the  form  enclosed, will be voted in respect thereto,  in  accordance
with the judgment of the persons voting such proxies.

                      ANNUAL REPORT AND FORM 10-K

     A   copy  of  the  Company's  1997  Annual  Report  is  enclosed.
Shareholders  not  receiving a copy of such Annual Report  may  obtain
one, without charge, upon request to the Company by writing or calling
the Company's investor relations representative, NeoPath, Inc., 8721 -
154th Avenue NE, Redmond, WA  98052, 1-800-NEOPATH.

     A  copy  of the Company's Annual Report on Form 10-K for the year
ended  December  31, 1997, as filed with the Secruities  and  Exchange
Commission,  will  be provided without charge to each  shareholder  of
record  who  submits  a  written request addressed  to  the  Company's
investor relations representative, NeoPath, Inc., 8721 - 154th  Avenue
NE, Redmond, WA  98052.

                                    By Order of the Board of Directors



                                    Alan C. Nelson
                                    President and
                                    Chief Executive Officer


Redmond, Washington
April 14, 1998

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<PAGE>
     
                                                                  
                                                                  
                                                        APPENDIX A
                                   
                             NEOPATH, INC.
                                   
                        1989 STOCK OPTION PLAN
             As Amended and Restated on February 26, 1998

Section 1.  Purpose

     The  purpose  of  the NeoPath, Inc. 1989 Stock Option  Plan  (this
"Plan")  is  to provide a means whereby selected employees,  directors,
officers, agents, consultants, advisors and independent contractors  of
NeoPath,  Inc.  (the  "Company"), or of any parent  or  subsidiary  (as
defined  in  subsection  5.8 and referred to  hereinafter  as  "related
corporations")  thereof, may be granted incentive stock options  and/or
nonqualified stock options to purchase the Common Stock (as defined  in
Section  3) of the Company, in order to attract and retain the services
or  advice of such employees, directors, officers, agents, consultants,
advisors and independent contractors and to provide added incentive  to
such persons by encouraging stock ownership in the Company.

Section 2.  Administration

     This  Plan shall be administered by the Board of Directors of  the
Company (the "Board") or a committee or committees (which term includes
subcommittees) appointed by, and consisting of two or more members  of,
the  Board.   The  administrator  of this  Plan  shall  hereinafter  be
referred  to  as  the "Plan Administrator."  So long as  the  Company's
common stock (the "Common Stock") is registered under Section 12(b)  or
12(g) of the Securities Exchange Act of 1934, as amended (the "Exchange
Act"),  the  Board shall consider, in selecting the Plan  Administrator
and  the  membership of any committee acting as Plan  Administrator  of
this  Plan  with  respect to any persons subject or likely   to  become
subject  to Section 16 under the Exchange Act, the provisions regarding
(a)  "outside  directors," as contemplated by  Section  162(m)  of  the
Internal  Revenue  Code  of  1986, as amended  (the  "Code"),  and  (b)
"nonemployee  directors,"  as contemplated  by  Rule  16b-3  under  the
Exchange   Act.    The  Board  may  delegate  the  responsibility   for
administering this Plan with respect to designated classes of  eligible
participants  to different committees, subject to such  limitations  as
the Board deems appropriate.

     The  members of any committee serving as Plan Administrator  shall
be  appointed  by the Board for such term as the Board  may  determine.
The Board may from time to time remove members from, or add members to,
the  committee.  Vacancies on the committee, however caused,  shall  be
filled by the Board.
     
     2.1  Procedures

     The  Board  shall  designate  one  of  the  members  of  the  Plan
Administrator as chairman.  The Plan Administrator may hold meetings at
such times and places as it shall determine.  The acts of a majority of
the  members of the Plan Administrator present at meetings at  which  a
quorum  exists, or acts reduced to or approved in writing by  all  Plan
Administrator members, shall be valid acts of the Plan Administrator.
     
     2.2  Responsibilities

     Except  for the terms and conditions explicitly set forth in  this
Plan,  the  Plan  Administrator  shall  have  the  authority,  in   its
discretion,  to  determine all matters relating to the  options  to  be
granted under this Plan, including selection of the individuals  to  be
granted options, the number of shares to be subject to each option, the
exercise  price,  and all other terms and conditions  of  the  options.
Grants under this Plan need not be identical in any respect, even  when
made  simultaneously.  The interpretation and construction by the  Plan
Administrator  of any terms or provisions of this Plan  or  any  option
issued  hereunder,  or  of  any  rule  or  regulation  promulgated   in
connection  herewith, shall be conclusive and binding on all interested
parties,  so long as such interpretation and construction with  respect
to  incentive stock options correspond to the requirements  of  Section
422  of  the  Code,  the  regulations  thereunder  and  any  amendments
thereto.
     
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<PAGE>
     
     2.3  Rule 16b-3 Compliance and Bifurcation of Plan

     Notwithstanding anything in this Plan to the contrary, the  Board,
in  its absolute discretion, may bifurcate this Plan so as to restrict,
limit  or  condition the application of any provision of this  Plan  to
participants who are subject to Section 16 of the Exchange Act  without
so  restricting,  limiting or conditioning this Plan  with  respect  to
other participants.

Section 3.  Shares Subject to This Plan

     The  shares  subject  to  this  Plan shall be  the  Common  Stock,
currently  authorized  but  unissued or subsequently  acquired  by  the
Company.  Subject to adjustment as provided in Section 7, the aggregate
amount of Common Stock to be delivered upon the exercise of all options
granted  under  this Plan shall not exceed 3,470,000  shares.   If  any
option  granted  under  this  Plan  shall  expire  or  be  surrendered,
exchanged  for  another option, canceled or terminated for  any  reason
without  having been exercised in full, the unpurchased shares  subject
thereto  shall thereupon again be available for purposes of this  Plan,
including for replacement options which may be granted in exchange  for
such expired, surrendered, exchanged, canceled or terminated options.

Section 4.  Eligibility

     An  incentive  stock option may be granted only to  an  individual
who,  at  the time the option is granted, is an employee of the Company
or  a  related corporation.  A nonqualified stock option may be granted
to  any  employee,  director, officer, agent,  consultant,  advisor  or
independent  contractor  of  the Company or  any  related  corporation,
whether  an  individual or an entity.  Any party to whom an  option  is
granted  under  this  Plan  shall  be referred  to  hereinafter  as  an
"Optionee."

Section 5.  Terms and Conditions of Options

     Options  granted  under this Plan shall be  evidenced  by  written
agreements which shall contain such terms, conditions, limitations  and
restrictions as the Plan Administrator shall deem advisable  and  which
are  not  inconsistent with this Plan.  Notwithstanding the  foregoing,
options  shall include or incorporate by reference the following  terms
and conditions:
     
     5.1  Number of Shares and Price

     The maximum number of shares that may be purchased pursuant to the
exercise of each option and the price per share at which such option is
exercisable (the "exercise price") shall be as established by the  Plan
Administrator;  provided, however, that the maximum  number  of  shares
with  respect  to  which an option or options may  be  granted  to  any
Optionee  in  any  one  fiscal year of the  Company  shall  not  exceed
400,000  shares  (the  "Maximum  Annual  Optionee  Grant").   The  Plan
Administrator  shall act in good faith to establish an  exercise  price
which  shall  be not less than the fair market value per share  of  the
Common  Stock  at  the  time  the option is  granted  with  respect  to
incentive  stock  options  and  also provided  that,  with  respect  to
incentive  stock options granted to greater than 10% shareholders,  the
exercise price shall be as required by subsection 6.1.
     
     5.2  Term and Maturity

     Subject to the restrictions contained in Section 6 with respect to
granting incentive stock options to greater than 10% shareholders,  the
term of each incentive stock option shall be as established by the Plan
Administrator  and, if not so established, shall be 10 years  from  the
date  it is granted but in no event shall it exceed 10 years.  The term
of  each nonqualified stock option shall be as established by the  Plan
Administrator and, if not so established, shall be 10 years.  To ensure
that the Company or a related corporation will achieve the purpose  and
receive  the benefits contemplated by this Plan, any option granted  to
any Optionee hereunder shall, unless the condition of this sentence  is
waived  or  modified  in  the agreement evidencing  the  option  or  by
resolution   adopted  at  any  time  by  the  Plan  Administrator,   be
exercisable according to the following schedule:
     
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<PAGE>
     
     For options granted prior to December 10, 1996:
                                                 
   Period of Optionee's                          
  Continuous Relationship                        
With the Company or Related      
 Corporation From the Date       Portion of Total Option Which Is
   the Option Is Granted                   Exercisable
___________________________      ________________________________

       after 1 year                            25%

   each month completed               an additional 1/36th
        thereafter                    of the remaining 75%

       after 4 years                           100%

For options granted after December 9, 1996:
                                                 
   Period of Optionee's                          
  Continuous Relationship                        
With the Company or Related      
 Corporation From the Date       Portion of Total Option Which Is
   the Option Is Granted                   Exercisable
____________________________     ________________________________

       after 1 year*                           25%

each year completed thereafter           an additional 25%

       after 4 years                           100%
________________
*For  options granted to new employees, the period shall be from  grant
date to 1 year after date of employment
     
     5.3  Exercise

     Subject to the vesting schedule described in subsection 5.2,  each
option  may be exercised in whole or in part at any time and from  time
to  time;  provided,  however, that only whole shares  will  be  issued
pursuant  to the exercise of any option.  An Option shall be  exercised
by  delivery  to  the Company of notice of the number  of  shares  with
respect to which the option is exercised, together with payment of  the
exercise price.
     
     5.4  Payment of Exercise Price

     Payment of the option exercise price shall be made in full at  the
time  the notice of exercise of the option is delivered to the  Company
and  shall  be in cash, bank certified or cashier's check, or  personal
check  (unless  at  the time of exercise the Plan  Administrator  in  a
particular  case  determines not to accept a personal  check)  for  the
shares being purchased.

     The  Plan  Administrator can determine at any time before exercise
that  additional  forms of payment will be permitted.   To  the  extent
permitted  by  applicable  laws  and regulations  (including,  but  not
limited  to, federal tax and securities laws and regulations and  state
corporate  law),  and  unless  the  Plan  Administrator  in  its   sole
discretion  determines  otherwise, an option  may  be  exercised  by  a
combination  of  cash  and/or check and one or both  of  the  following
additional forms:

     (a)   tendering  (either  actually or by  attestation)  shares  of
Common  Stock of the Company held by an Optionee having a  fair  market
value  equal  to  the  exercise price, such fair  market  value  to  be
determined in good faith by the Plan Administrator; provided,  however,
that payment in stock held by an Optionee shall not be made unless  the
stock  shall have been owned by the Optionee for a period of  at  least
six  months (or any shorter period necessary to avoid a charge  to  the
Company's earnings for financial accounting purposes); or

     (b)   delivery  of  a properly executed exercise notice,  together
with  irrevocable instructions to a broker, all in accordance with  the
regulations  of the Federal Reserve Board, to promptly deliver  to  the
Company  the amount of sale or loan proceeds to pay the exercise  price
and  any  federal, state or local withholding tax obligations that  may
arise in connection with the exercise.
     
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<PAGE>
     
     In  addition,  the  exercise price for shares purchased  under  an
option may be paid, either singly or in combination with one or more of
the  alternative  forms of payment authorized by this Section  5.4,  by
(y)  delivery  of  a  full-recourse promissory  note  executed  by  the
Optionee; provided that (i) such note delivered in connection  with  an
incentive  stock  option shall, and such note delivered  in  connection
with  a  nonqualified stock option may, in the sole discretion  of  the
Plan  Administrator,  bear interest at a rate  specified  by  the  Plan
Administrator  but  in  no case less than the rate  required  to  avoid
imputation  of  interest (taking into account  any  exceptions  to  the
imputed interest rules) for federal income tax purposes, (ii) the  Plan
Administrator in its sole discretion shall specify the term  and  other
provisions  of  such  note  at the time an incentive  stock  option  is
granted  or  at  any  time prior to exercise of  a  nonqualified  stock
option,  (iii)  the  Plan Administrator may require that  the  Optionee
pledge  to the Company for the purpose of securing the payment of  such
note  the  shares  of Common Stock to be issued to  the  Optionee  upon
exercise   of   the  option  and  may  require  that  the   certificate
representing  such  shares be held in escrow in order  to  perfect  the
Company's  security  interest, and (iv) the Plan Administrator  in  its
sole  discretion  may at any time restrict or rescind this  right  upon
notification  to the Optionee; or (z) such other consideration  as  the
Plan Administrator may permit.
     
     5.5  Withholding Tax Requirement

     At  its  discretion, the Company may require an Optionee receiving
shares  of Common Stock to reimburse the Company for any taxes required
by  any  government to be withheld by the Company or otherwise deducted
and  paid  with respect to an option, and may withhold any distribution
in  whole  or  in  part  until the Company is so reimbursed.   In  lieu
thereof, the Company shall have the right to withhold from any cash  or
other amounts due or to become due from the Company to the Optionee  an
amount  equal to such taxes.  The Company may also retain and  withhold
or  the  Optionee  may elect, unless the Plan Administrator  determines
otherwise, to have the Company retain and withhold a number  of  shares
having  a  market value not less than the amount of such taxes required
to  be  withheld by the Company to reimburse the Company for  any  such
taxes and cancel (in whole or in part) any such shares so withheld.
     
     5.6  Holding Periods
          
          5.6.1     Securities and Exchange Act Section 16

     If  an  individual subject to Section 16 of the Exchange Act sells
shares  of  Common Stock obtained upon the exercise of a  stock  option
within six months after the date the option was granted, such sale  may
result  in  short-swing profit liability under  Section  16(b)  of  the
Exchange Act.
          
          5.6.2     Taxation of Stock Options

     In  order  to  obtain certain tax benefits afforded  to  incentive
stock options under Section 422 of the Code, an Optionee must hold  the
shares  issued upon the exercise of an incentive stock option  for  two
years after the date of grant of the option and one year from the  date
of exercise.  An Optionee may be subject to the alternative minimum tax
at the time of exercise of an incentive stock option.

     The Plan Administrator may require an Optionee to give the Company
prompt notice of any disposition of shares acquired by the exercise  of
an  incentive  stock  option prior to the expiration  of  such  holding
periods.

     Tax  advice should be obtained by an Optionee when exercising  any
option  and  prior  to the disposition of the shares  issued  upon  the
exercise of any option.
     
     5.7  Transferability of Options

     Options   granted   under   this   Plan   and   the   rights   and  
privileges   conferred   hereby  may   not  be  transferred,  assigned,  
pledged   or   hypothecated  in   any  manner  (whether  by   operation 
of  law  or  otherwise)  other  than  by  will  or  by  the  applicable  
laws  of  descent   and  distribution  and  shall  not  be  subject  to  
execution,  attachment  or  similar  process.   During  an   Optionee's 
lifetime,  any   options  granted   under  this Plan  are  personal  to  
him or her and are exercisable  solely  by such Optionee or a permitted 
assignee   or  transferee  of  such   Optionee   (as  provided  below).   
Any  attempt  to  transfer,  assign,  pledge,  hypothecate or otherwise

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<PAGE>
     
dispose  of  any  option under this Plan or of any right  or  privilege
conferred  hereby,  contrary to the Code or to the provisions  of  this
Plan, or the sale or levy or any attachment or similar process upon the
rights  and  privileges  conferred  hereby  shall  be  null  and  void.
Notwithstanding the foregoing, to the extent permitted by  Section  422
of  the  Code,  the  Plan  Administrator  may  permit  an  Optionee  to
(i) during the Optionee's lifetime, designate a person who may exercise
the  option after the Optionee's death by giving written notice of such
designation to the Company (such designation may be changed  from  time
to  time  by  the  Optionee by giving written  notice  to  the  Company
revoking  any  earlier  designation and making a  new  designation)  or
(ii)  transfer  the  option  and the rights  and  privileges  conferred
hereby;  provided, however, that any option so assigned or  transferred
shall be subject to all the same terms and conditions contained in  the
instrument evidencing the award.
     
     5.8  Termination of Relationship

     If  the  Optionee's relationship with the Company or  any  related
corporation  ceases for any reason, then the portion of the  Optionee's
option  that  is  not exercisable at the time of such  cessation  shall
terminate   immediately   upon   such  cessation,   unless   the   Plan
Administrator  determines  otherwise.  If the  Optionee's  relationship
with the Company or any related corporation ceases for any reason other
than  termination for cause, death or total disability, and  unless  by
its  terms  the option sooner terminates or expires, then the  Optionee
may  exercise, for a three-month period, that portion of the Optionee's
option  which  is  exercisable at the time of such cessation,  but  the
Optionee's  option shall terminate at the end of such period  following
such  cessation as to all shares for which it has not theretofore  been
exercised,  unless such provision is waived in the agreement evidencing
the  option, or at any time prior to the expiration of the  option,  by
the  Plan  Administrator in its sole discretion.  If, however,  in  the
case  of an incentive stock option, the Optionee does not exercise  the
Optionee's  option within three months after cessation  of  employment,
the  option  will no longer qualify as an incentive stock option  under
the Code.

     If  an  Optionee  is  terminated for cause,  each  option  granted
hereunder  shall automatically terminate as of the first  discovery  by
the  Company of any reason for termination for cause, and such Optionee
shall  thereupon have no right to purchase any shares pursuant to  such
option.   "Termination for cause" shall mean dismissal for  dishonesty,
conviction  or confession of a crime (except minor violations),  fraud,
misconduct or disclosure of confidential information.  If an Optionee's
relationship  with the Company or any related corporation is  suspended
pending  an  investigation  of whether or not  the  Optionee  shall  be
terminated  for cause, the Optionee's rights under each option  granted
hereunder   likewise   shall  be  suspended  during   the   period   of
investigation.

     If  an  Optionee's relationship with the Company  or  any  related
corporation  ceases because of a total disability, the portion  of  the
Optionee's  option  that is exercisable at the time of  such  cessation
shall not terminate or, in the case of an incentive stock option, cease
to  be  treated as an incentive stock option until the end of  the  12-
month  period following such cessation (unless by its terms  it  sooner
terminates  or  expires).   As  used in  this  Plan,  the  term  "total
disability"  refers to a mental or physical impairment of the  Optionee
which is expected to result in death or which has lasted or is expected
to  last for a continuous period of 12 months or more and which  causes
the  Optionee  to  be  unable, in the opinion of the  Company  and  two
independent  physicians, to perform his or her duties for  the  Company
and   to  be  engaged  in  any  substantial  gainful  activity.   Total
disability shall be deemed to have occurred on the first day after  the
Company and the two independent physicians have furnished their opinion
of total disability to the Plan Administrator.

     The  Plan Administrator, in its absolute discretion, may determine
all  questions  of  whether particular leaves of absence  constitute  a
termination  of  services;  provided, however,  that  with  respect  to
incentive  stock options, such determination shall be  subject  to  any
requirements  contained  in  the Code.  The foregoing  notwithstanding,
with respect to incentive stock options, employment shall not be deemed
to  continue  beyond  the  first 90 days  of  such  leave,  unless  the
Optionee's  reemployment  rights  are  guaranteed  by  statute  or   by
contract.

     As  used herein, the term "related corporation," when referring to
a  subsidiary corporation, shall mean any corporation (other  than  the
Company)  in,  at the time of the granting of the option,  an  unbroken
chain of corporations ending with the Company, if stock possessing  50%
or  more of the total combined voting power of all classes of stock  of
each of the corporations other than the Company is owned by one of  the
other   corporations  in  such  chain.   When  referring  to  a  parent
corporation, the term "related corporation" shall mean any  corporation
in an unbroken chain of corporations ending with the Company if, at the
time of the granting of the option, each of the corporations other than
the  Company  owns stock possessing 50% or more of the  total  combined
voting  power  of all classes of stock in one of the other corporations
in such chain.
     
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<PAGE>
     
     5.9  Death of Optionee

     If  an  Optionee dies while he or she has a relationship with  the
Company or any related corporation or within the three-month period (or
12-month  period  in the case of totally disabled Optionees)  following
cessation of such relationship, any option held by such Optionee to the
extent  that  the  Optionee would have been entitled to  exercise  such
option, may be exercised within one year after his or her death by  the
personal  representative  of his or her estate  or  by  the  person  or
persons  to  whom  the Optionee's rights under the  option  shall  pass
(i)  by  will or by the applicable laws of descent and distribution  or
(ii) by a designation or transfer pursuant to Section 5.7.
     
     5.10 No Status as Shareholder

     Neither the Optionee nor any party to which the Optionee's  rights
and  privileges under the option may pass shall be, or have any of  the
rights  or privileges of, a shareholder of the Company with respect  to
any  of  the  shares issuable upon the exercise of any  option  granted
under this Plan unless and until such option has been exercised.
     
     5.11 Continuation of Relationship

     Nothing  in  this  Plan  or in any option shall  confer  upon  any
Optionee  any right to continue in the employ or other relationship  of
the  Company or of a related corporation, or to interfere  in  any  way
with  the  right  of the Company or of any such related corporation  to
terminate his or her employment or other relationship with the  Company
at any time.
     
     5.12 Modification and Amendment of Option

     Subject  to  the requirements of Code Section 422 with respect  to
incentive stock options and to the terms and conditions and within  the
limitations  of this Plan, the Plan Administrator may modify  or  amend
any  outstanding  option granted under this Plan.  The modification  or
amendment  of an outstanding option shall not, without the  consent  of
the Optionee, impair or diminish any of his or her rights or any of the
obligations  of  the  Company under such option.  Except  as  otherwise
provided  in  this  Plan,  no outstanding option  shall  be  terminated
without the consent of the Optionee.
     
     5.13 Limitation on Value for Incentive Stock Options

     As  to all incentive stock options granted under the terms of this
Plan,  to the extent that the aggregate fair market value of the shares
(determined  at  the time the incentive stock option is  granted)  with
respect to which incentive stock options are exercisable for the  first
time by the Optionee during any calendar year (under this Plan and  all
other   incentive  stock  option  plans  of  the  Company,  a   related
corporation  or  a  predecessor  corporation)  exceeds  $100,000,  such
options  shall be treated as nonqualified stock options.  The  previous
sentence  shall  not  apply if the Internal Revenue  Service  issues  a
public  rule, issues a private ruling to the Company, any  Optionee  or
any  legatee, personal representative or distributee of an Optionee  or
issues regulations changing or eliminating such annual limit.

Section 6.  Greater Than 10% Shareholders
     
     6.1  Exercise Price and Term of Incentive Stock Options

     If  an  incentive stock option is granted under this Plan  to  any
employee  who owns more than 10% of the total combined voting power  of
all  classes  of  stock of the Company or any related corporation,  the
term  of  such incentive stock options shall not exceed five years  and
the exercise price shall be not less than 110% of the fair market value
of  the shares at the time the incentive stock option is granted.  This
provision shall control notwithstanding any contrary terms contained in
an option agreement or any other document.
     
     6.2  Attribution Rule

     For    purposes   of   subsection   6.1,   in   determining  stock 
ownership,  an  employee   shall   be   deemed   to   own   the  shares  
owned,  directly  or  indirectly,  by  or  for  his  or  her  brothers, 
sisters,   spouse,  ancestors  and  lineal  descendants.  Shares owned,
     
A-6
<PAGE>
     
directly or indirectly, by or for a corporation, partnership, estate or
trust  shall  be  deemed  to be owned proportionately  by  or  for  its
shareholders, partners or beneficiaries.  If an employee  or  a  person
related  to  the  employee owns an unexercised  option  or  warrant  to
purchase  shares of the Company, the shares subject to that portion  of
the  option  or  warrant which is unexercised shall not be  counted  in
determining  stock ownership.  For purposes of this Section  6,  shares
owned  by  an  employee shall include all shares  actually  issued  and
outstanding immediately before the grant of the incentive stock  option
to the employee.

Section 7.  Adjustments Upon Changes in Capitalization

     The aggregate number and class of shares for which options may  be
granted under this Plan, the Maximum Annual Optionee Grant set forth in
Section 5.1, the number and class of shares covered by each outstanding
option  and  the exercise price per share thereof (but  not  the  total
price),  shall  all  be proportionately adjusted for  any  increase  or
decrease in the number of issued shares of Common Stock of the  Company
resulting  from  a  split-up or consolidation of  shares  or  any  like
capital adjustment, or the payment of any stock dividend.
     
     7.1  Effect of Liquidation or Reorganization

          7.1.1  Cash, Stock or Other Property for Stock

     Except as provided in subsection 7.1.2, upon a merger (other  than
a  merger of the Company in which the holders of shares of Common Stock
immediately  prior to the merger have the same proportionate  ownership
of  shares  of  Common  Stock in the surviving corporation  immediately
after  the  merger), consolidation, acquisition of property  or  stock,
separation,  reorganization (other than a mere reincorporation  or  the
creation  of  a  holding company) or liquidation of the Company,  as  a
result of which the shareholders of the Company receive cash, stock  or
other  property in exchange for or in connection with their  shares  of
Common  Stock,  any option granted hereunder shall terminate,  but  the
Optionee  shall  have the right immediately prior to any  such  merger,
consolidation,   acquisition   of  property   or   stock,   separation,
reorganization  or  liquidation to exercise such Optionee's  option  in
whole  or in part whether or not the vesting requirements set forth  in
the option agreement have been satisfied.

          7.1.2  Conversion of Options on Stock for Stock Exchange

     If  the  shareholders  of  the Company receive  capital  stock  of
another corporation ("Exchange Stock") in exchange for their shares  of
Common Stock in any transaction involving a merger (other than a merger
of  the Company in which the holders of Common Stock immediately  prior
to  the merger have the same proportionate ownership of Common Stock in
the surviving corporation immediately after the merger), consolidation,
acquisition  of property or stock, separation or reorganization  (other
than a mere reincorporation or the creation of a holding company),  all
options  granted hereunder shall be converted into options to  purchase
shares of Exchange Stock unless the Company and the corporation issuing
the Exchange Stock, in their sole discretion, determine that any or all
such  options granted hereunder shall not be converted into options  to
purchase  shares  of  Exchange Stock but  instead  shall  terminate  in
accordance  with the provisions of subsection 7.1.1.   The  amount  and
price  of converted options shall be determined by adjusting the amount
and  price  of the options granted hereunder in the same proportion  as
used for determining the number of shares of Exchange Stock the holders
of  the  shares  of Common Stock receive in such merger, consolidation,
acquisition  of  property or stock, separation or reorganization.   The
converted  options  shall be fully vested whether or  not  the  vesting
requirements  set  forth in the option agreement  have  been  satisfied
provided  that such acceleration will not occur if, in the  opinion  of
the  Company's  outside  accountants, such  acceleration  would  render
unavailable  "pooling  of  interests"  accounting  treatment  for   any
reorganization,  merger  or consolidation  of  the  Company  for  which
pooling of interests accounting treatment is sought by the Company.

     Upon  a merger of the Company in which the holders of Common Stock
immediately  prior to the merger have the same proportionate  ownership
of  common  stock  in the surviving corporation immediately  after  the
merger,  a  mere reincorporation or the creation of a holding  company,
each  option  outstanding  under this  Plan  shall  be  assumed  or  an
equivalent option shall be substituted by the successor corporation  or
a  parent  or subsidiary of such corporation, and the vesting  schedule
set  forth  in the instrument evidencing the option shall  continue  to
apply to such assumed or equivalent option.
     
A-7
<PAGE>
     
     7.2  Fractional Shares

     In  the event of any adjustment in the number of shares covered by
any  option, any fractional shares resulting from such adjustment shall
be disregarded and each such option shall cover only the number of full
shares resulting from such adjustment.
     
     7.3  Determination of Board to Be Final

     All  Section  7  adjustments shall be made by the Board,  and  its
determination  as  to what adjustments shall be made,  and  the  extent
thereof,  shall be final, binding and conclusive.  Unless  an  Optionee
agrees otherwise, any change or adjustment to an incentive stock option
shall be made in such a manner so as not to constitute a "modification"
as  defined  in Code Section 425(h) and so as not to cause his  or  her
incentive stock option issued hereunder to fail to continue to  qualify
as an incentive stock option as defined in Code Section 422(b).

Section 8.  Securities Regulation

     Shares shall not be issued with respect to an option granted under
this  Plan  unless  the exercise of such option and  the  issuance  and
delivery of such shares pursuant thereto shall comply with all relevant
provisions of law, including, without limitation, any applicable  state
securities  laws, the Securities Act of 1933, as amended, the  Exchange
Act,  the  rules  and  regulations  promulgated  thereunder,  and   the
requirements of any stock exchange upon which the shares  may  then  be
listed, and shall be further subject to the approval of counsel for the
Company with respect to such compliance, including the availability, if
applicable, of an exemption from registration for the issuance and sale
of  any shares hereunder.  Inability of the Company to obtain, from any
regulatory  body  having  jurisdiction, the  authority  deemed  by  the
Company's counsel to be necessary for the lawful issuance and  sale  of
any  shares  hereunder  or  the unavailability  of  an  exemption  from
registration  for the issuance and sale of any shares  hereunder  shall
relieve  the Company of any liability in respect of the nonissuance  or
sale of such shares as to which such requisite authority shall not have
been obtained.

     As  a  condition  to the exercise of an option,  the  Company  may
require  the Optionee to represent and warrant at the time of any  such
exercise  that  the shares are being purchased only for investment  and
without any present intention to sell or distribute such shares if,  in
the  opinion  of  counsel  for the Company, such  a  representation  is
required by any relevant provision of the aforementioned laws.  At  the
option  of  the  Company, a stop-transfer order against any  shares  of
stock  may  be  placed on the official stock books and records  of  the
Company,  and  a legend indicating that the stock may not  be  pledged,
sold or otherwise transferred, unless an opinion of counsel is provided
(concurred in by counsel for the Company) stating that such transfer is
not in violation of any applicable law or regulation, may be stamped on
stock certificates in order to assure exemption from registration.  The
Plan  Administrator may also require such other action or agreement  by
the  Optionees as may from time to time be necessary to comply with the
federal  and state securities laws.  THIS PROVISION SHALL NOT  OBLIGATE
THE   COMPANY  TO  UNDERTAKE  REGISTRATION  OF  THE  OPTIONS  OR  STOCK
HEREUNDER.

     Should any of the Company's capital stock of the same class as the
stock  subject  to options granted hereunder be listed  on  a  national
securities  exchange,  all  stock issued hereunder  if  not  previously
listed  on  such  exchange shall be authorized  by  that  exchange  for
listing thereon prior to the issuance thereof.

Section 9.  Amendment and Termination
     
     9.1  Board Action

     The  Board may at any time suspend, amend or terminate this  Plan,
provided  that, to the extent required for compliance with Section  422
of  the  Code  or  by any applicable law or regulation,  the  Company's
shareholders must approve any amendment which will:

      (a)  increase the total number of shares that may be issued under
this Plan;

      (b)   modify the class of participants eligible for participation
in this Plan; or

A-8
<PAGE>

      (c)   otherwise require shareholder approval under any applicable
law or regulation.

     Such shareholder approval must be obtained within 12 months of the 
adoption by the Board of such amendment.

     Any  amendment made to this Plan since its original adoption which
would   constitute   a  "modification"  to  incentive   stock   options
outstanding  on the date of such amendment, shall not be applicable  to
such  outstanding  incentive stock options, but shall have  prospective
effect only, unless the Optionee agrees otherwise.
     
     9.2  Automatic Termination

     Unless  sooner terminated by the Board, this Plan shall  terminate
ten  years  from  the  earlier of (a) the date on which  this  Plan  is
adopted by the Board or (b) the date on which this Plan is approved  by
the  shareholders of the Company.  No option may be granted after  such
termination  or during any suspension of this Plan.  The  amendment  or
termination of this Plan shall not, without the consent of  the  option
holder,  alter  or  impair any rights or obligations under  any  option
theretofore granted under this Plan.

Section 10.  Effectiveness of This Plan

     This  Plan  shall become effective upon adoption by the  Board  so
long as it is approved by the Company's shareholders at any time within
12  months  of such adoption of this Plan or, if earlier,  and  to  the
extent required for compliance with Rule 16b-3 under the Exchange  Act,
at the next annual meeting of shareholders after adoption by the Board.

     Original Plan adopted by the Board on May 23, 1989 and approved by
the  shareholders on May 30, 1989.  Plan was amended on March 15, 1991,
July  15,  1991, and November 18, 1991.  Plan amended and  restated  on
March 27, 1992, on January 22, 1993 and on August 19, 1993; restated by
the  Board  on  October 26, 1994 and approved by  the  shareholders  on
November 17, 1994; amended and restated by the Board on April 25,  1996
and  approved by the Company's shareholders on June 25, 1996.   Amended
and  restated  by  the Board on December 10, 1996 and on  February  26,
1998,  and  approved  by the Company's shareholders on  ______________,
1998.

A-9
<PAGE>
     
                             NEOPATH, INC.
       This Proxy is Solicited by the Board of Directors for the
            Annual Meeting of Shareholders -- May 21, 1998

      The  undersigned hereby appoint(s) Alan C. Nelson and William  L.
Scott and each of them as proxies, with full power of substitution,  to
represent and vote as designated all shares of Common Stock of NeoPath,
Inc.  held of record by the undersigned on March 25, 1998 at the Annual
Meeting  of Shareholders of the Company to be held at The Hyatt Regency
Bellevue  at Bellevue Place, 900 Bellevue Way NE, Bellevue, Washington,
at  8:30  a.m. (Pacific daylight time) on Thursday, May 21, 1998,  with
authority  to  vote upon the matters listed on the other side  of  this
proxy  card  and with discretionary authority as to any  other  matters
that  may  properly  come  before the meeting  or  any  adjournment  or
postponement thereof.

         IMPORTANT -- PLEASE DATE AND SIGN ON THE OTHER SIDE.
                                   
<PAGE>

                   Please date, sign and mail your
                 proxy card back as soon as possible!
                                   
                    Annual Meeting of Shareholders
                             NEOPATH, INC.
                                   
                             May 21, 1998
                                   
                                   
                                   
                                   
____________________________________________________________
A [x]  Please mark your votes as in this example.

The Board of Directors recommends a vote "FOR all Nominees" in Item  1,
and "FOR" Item 2.

                                        WITHHOLD
                         FOR            AUTHORITY
                    all Nominees   to vote for all Nominees
(1)  ELECTION
          OF
     DIRECTORS           [ ]               [ ]
     
WITHHOLD for the following only:  (Write the name of the nominee(s) in
the space below)

____________________________________________________________

     NOMINEES: Alan C. Nelson
               Thomas A. Bonfiglio

                            FOR     AGAINST     ABSTAIN
(2)  Amendment of 1989      [ ]       [ ]        [ ]
     Restated Stock
     Option Plan
     
SHARES  REPRESENTED  BY THIS PROXY WILL BE VOTED  AS  DIRECTED  BY  THE
SHAREHOLDERS  IN THE SPACE PROVIDED.  IF NO DIRECTION  IS  GIVEN,  THIS
PROXY WILL BE VOTED "FOR ALL NOMINEES" IN ITEM 1 AND "FOR" ITEM 2.

I plan to attend the Annual Meeting [ ]

PLEASE DATE,SIGN AND RETURN PROMPTLY.

SIGNATURE(S)________________________ DATE____________

NOTE:  Please  sign  exactly  as your name appears  hereon.  Attorneys,
trustees,  executors and other fiduciaries acting in  a  representative
capacity  should sign their names and give their titles.  An authorized
person   should   sign   on   behalf  of  corporations,   partnerships,
associations, etc. and give his or her title.  If your shares are  held
by  two  or more persons, each person must sign.  Receipt of the notice
of meeting and proxy statement is hereby acknowledged.



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