EUROMED INC
8-K/A, 1996-10-11
DRUGS, PROPRIETARIES & DRUGGISTS' SUNDRIES
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<PAGE>   1



                       SECURITIES AND EXCHANGE COMMISSION

                            Washington, D.C.  20549


                                   FORM 8-K/A
                                AMENDMENT NO. 1

                                 CURRENT REPORT


     Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934



   Date of Report (Date of earliest event reported)    July 5, 1996          
                                                    -------------------

                               EuroMed, Inc.                        
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)



            Nevada                      0-27720                    88-031770 
       --------------                ------------            -------------------
(State or other jurisdiction          (Commission               (IRS Employer
     of incorporation                File Number)            Identification No.)
                                                         


       Wilhelminakanaal Noord 6, NL 4902VR Oosterhout, The Netherlands
- ----------------------------------------------------------------------------
   (Address of principal executive offices)                    (Zip Code)


 Registrant's telephone number, including area code       011-31-16-203-7440   
                                                    ---------------------------
<PAGE>   2


     Reference is made to the Current Report on Form 8-K (the "Form 8-K") filed
by EuroMed, Inc. on July 19, 1996.  The Item 7 of the Form 8-K is hereby
amended to read in its entirety as follows:

ITEM 7.  FINANCIAL STATEMENTS AND EXHIBITS.

         (a)     Financial Statements of business acquired in the 
                 Transaction.(1)

                 (i)      Consolidated Balance Sheet.

                 (ii)     Interim Consolidated Balance Sheet.

                 (iii)    Consolidated Statement of Income.

                 (iv)     Interim Consolidated Statement of Income.

                 (v)      Consolidated Statement of Cash Flows.

                 (vi)     Interim Consolidated Statement of Cash Flows.

         (b)     Pro forma Financial Information for the Transaction.(1)

                 (i)      Pro forma Condensed Balance Sheet.

                 (ii)     Pro forma Condensed Consolidated Statement of Income.

         (c)     Exhibits.

         The following is a list of exhibits filed as part of this Current
Report on Form 8-K:

             Exhibit No.                    Description
             -----------                    -----------

                 2.1      Stock Purchase Agreement dated as of June 19, 1996,
                          by and among Registrant, Purchaser, Doets,
                          Roozekrans, Mutarestes, Pluripharm and FDNW.(4)

                 2.2      Stock Purchase Agreement, dated as of June 19, 1996,
                          by and among Registrant, Purchaser, Doets and
                          Roozekrans.(1)

                 4.1      Restated Articles of Incorporation of the Company.(2)

                 4.2      Bylaws of the Company.(2)




                                      2
<PAGE>   3
                 4.3      Specimen of Common Stock Certificate.(3)

                 10.1     Consulting, Management and Noncompetition Agreement,
                          dated as of July 5, 1996, by and between Purchaser
                          and Doets.(1)

                 10.2     Consulting, Management and Noncompetition Agreement,
                          dated as of July 5, 1996, by and between Purchaser
                          and Roozekrans.(1)

                 10.3     Consulting, Management and Noncompetition Agreement,
                          dated as of July 5, 1996, by and between Purchaser
                          and Hinnen.(1)




- ------------------------------

         (1)     Filed herewith.


         (2)     Previously filed as an exhibit to Registration No. 33-80801 on
                 Form S-1 and incorporated herein by reference.

         (3)     Previously filed as an exhibit to Amendment No. 1 to
                 Registration No. 33-80801 on Form S-1 and incorporated herein
                 by reference.

         (4)     Previously filed.








                                      3
<PAGE>   4
                                                                            1/13


Financial statements prepared
under US-Generally accepted
accounting principles of


Mutarestes B.V.
at Heerhugowaard


Velsen-Noord,
June 10, 1996
<PAGE>   5
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 2/13
at Heerhugowaard                                            3457202-1995-637bf-4


INDEX                                                                       Page




FINANCIAL STATEMENTS PREPARED UNDER US-GAAP

Financial statements
                                                                            
o        Auditors' report                                                    4
o        Consolidated balance sheet                                          5
o        Consolidated statement of income                                    6
o        Statement of shareholders' equity                                   7
o        Consolidated statement of cash flows                                8
o        Notes to the consolidated financial statements                      9
<PAGE>   6
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 3/13
at Heerhugowaard                                            3457202-1995-637bf-4





                                                   FINANCIAL STATEMENTS PREPARED
                                                   UNDER US-GAAP
                                                   (included on pages
                                                   4-13)

                                                   o       Financial statements
<PAGE>   7
                         [DELOITTE & TOUCHE LETTERHEAD]

                                                                       Page 4/13



To the Board of Directors of
Mutarestes B.V. at Heerhugowaard,
The Netherlands




June 10, 1996                                      L.M. van der Pal RA


AUDITOR'S REPORT

We have audited the consolidated balance sheets of Mutarestes B.V. as of
December 31, 1995 and 1994, and the related consolidated statements of income,
shareholders' equity, and cash flows for each of the three years in the period
ended December 31, 1995 (all expressed in Dutch Guilders).  These consolidated
financial statements are the responsibility of Mutarestes' management.  Our
responsibility is to express an opinion on these financial statements based on
our audits.

We conducted our audits in accordance with auditing standards generally
accepted in the Netherlands and the United States of America.  Those standards
require that we plan and perform the audit to obtain reasonable assurance about
whether the financial statements are free of material misstatement.  An audit
includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements.  An audit also includes assessing the
accounting principles used and significant estimates made by management, as
well as evaluating the overall financial statement presentation.  We believe
that our audits provide a reasonable basis for our opinion.

In our opinion, such consolidated financial statements present fairly, in all
material respects, the financial position of Mutarestes B.V. as of December 31,
1995 and 1994, and the results of its operations and its cash flows for each of
the three years in the period ended December 31, 1995 in conformity with
accounting principles generally accepted in the United States of America.

DELOITTE & TOUCHE
<PAGE>   8
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 5/13
at Heerhugowaard                                            3457202-1995-637bf-4

CONSOLIDATED BALANCE SHEET
(after appropriation of result)

<TABLE>
<CAPTION>
                               Notes                             December 31, 1994                      December 31, 1995
                               -----       ---------------------------------------   ------------------------------------
                                                                               DFL                                    DFL
 <S>                                  <C>              <C>              <C>              <C>                <C>
 ASSETS

 CURRENT ASSETS

 Cash and cash equivalents                                               2,784,778                            7,059,432
 -------------------------                                                                                             

 Accounts receivable-trade                              4,646,379                         4,676,034
 Other receivables                     1                  557,421                           223,817
                                                       ----------                        ----------

                                                                         5,203,800                            4,899,851
 Inventory                                                               1,840,889                            2,144,310

 FIXED ASSETS

 Tangible fixed assets
 ---------------------

 Machinery and equipment                                                    22,735                              179,200
                                                                        ----------                           ----------

 Total assets                                                            9,852,202                           14,282,793
                                                                        ==========                           ==========


 LIABILITIES

 CURRENT LIABILITIES

 Accounts payable                                       2,678,083                         2,794,160
 Payable to shareholders               2                1,597,259                         3,685,259
 Current tax liability                                  1,131,196                         1,544,077
 Other liabilities                     3                4,317,664                         5,963,103
                                                       ----------                        ----------
                                                                         9,724,202                           13,986,599

 SHAREHOLDERS' EQUITY                  4

 Paid-up share capital *)                                 128,000                            40,000
 Retained earnings                                              0                           256,194
                                                       ----------                        ----------

                                                                           128,000                              296,194
                                                                        ----------                           ----------
 Total liabilities and
 shareholders' equity                                                    9,852,202                           14,282,793
                                                                        ==========                           ==========
</TABLE>


*)       200 shares are authorized, par value of Dfl 1,000 per share,
         128 shares issues and outstanding as of December 31, 1994.
         200,000 shares and authorized, par value of Dfl 1 per share,
          40,000 shares issued are outstanding as of December 31, 1995.
<PAGE>   9
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 6/13
at Heerhugowaard                                            3457202-1995-637bf-4



CONSOLIDATED STATEMENT OF INCOME

          
          
          
<TABLE>   
<CAPTION>
                                                                        Fiscal years ended
                                                          ----------------------------------------------                    
                                           Notes               1993              1994               1995
                                           -----          ---------         ---------          ---------
                                                                DFL               DFL                DFL
 <S>                                         <C>         <C>               <C>                <C>
 Sales                                        5          46,376,683        49,356,531         61,059,320
 Discounts                                                7,251,626         7,755,417         10,395,751
 Cost of sales                                           36,595,566        38,994,336         46,523,220
                                                         ----------        ----------         ----------
                                                          2,529,491         2,606,778          4,140,349
                                                                                        
 Selling, general and                                       642,891           451,380            760,467
 administrative expenses                                 ----------        ----------         ----------
                                                                                        
                                                          1,886,600         2,155,398          3,379,882
                                                                                        
 Net financial income and expenses                        1,075,987           660,074             89,249
                                                         ----------        ----------         ----------
                                                                                        
 OPERATING INCOME                                         2,962,587         2,815,472          3,469,131
                                                                                        
 Corporate income tax                                     1,063,553         1,004,175          1,212,937
                                                         ----------        ----------         ----------
 NET INCOME                                               1,899,034         1,811,297          2,256,194
                                                         ==========        ==========         ==========
</TABLE>
<PAGE>   10
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 7/13
at Heerhugowaard                                            3457202-1995-637bf-4



STATEMENT OF SHAREHOLDERS' EQUITY


<TABLE>
<CAPTION>
                              Number of                                                                  Total
                               ordinary      Issued share          Retained    Unappropriated    shareholders'
                                 shares          capitial          earnings            result           equity
                              ---------      ------------          --------    --------------    -------------
                                                      DFL               DFL               DFL              DFL
<S>                              <C>              <C>           <C>                <C>              <C>
Balance at January
1, 1993                             128           128,000         9,305,328         1,336,506        10,769,834
Appropriation result
1992                                                              1,336,506        -1,336,506
Dividends paid to
shareholders                                                     -2,804,440                          -2,804,440
Net income                                                                          1,899,034         1,899,034
                                                  -------       -----------        ----------       -----------
Balance at December
31, 1993                                          128,000         7,837,394         1,899,034         9,864,428

Appropriation 
result 1993                                                       1,899,034        -1,899,034
Net income                                                        1,811,297                           1,811,297
Dividend paid to
shareholders                                                    -11,547,725                         -11,547,725
                                                  -------       -----------        ----------       -----------

Balance at December
31, 1994                                          128,000                 -                 -           128,000

Return of capital                                 -88,000                                               -88,000
Change in par value                -128
of shares                        40,000
Net income                                                        2,256,194                           2,256,194
Dividend paid to
shareholders                                                     -2,000,000                          -2,000,000
                                 ------           -------       -----------        ----------       -----------

Balance at December
31, 1995                         40,000            40,000           256,194                 -           296,194
                                 ======           =======       ===========        ==========       ===========
</TABLE>
<PAGE>   11
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 8/13
at Heerhugowaard                                            3457202-1995-637bf-4

CONSOLIDATED STATEMENT OF CASH FLOWS

<TABLE>
<CAPTION>
                                                           Fiscal years ended               
                                                  -----------------------------------------
                                                    1993          1994               1995
                                                  --------      --------           --------
                                                   DFL 000       DFL 000            DFL 000
<S>                                               <C>           <C>                  <C>
Operating activities
- --------------------

Net income                                          1,899         1,811              2,256
Adjustments to reconcile net income to
net cash provided by operating
activities:
 Depreciation                                          47            41                 50
Changes in assets and liabilities that
provided (used) cash:
   Accounts receivable                                161        (1,450)               (30)
   Inventory                                        (182)        (1,280)              (303)
   Other assets                                      (70)           121                334
   Accounts payable                                    99           295                116
   Other accrued liabilities                           32         2,167              2,058
                                                ---------    ----------         ----------

Cash provided by operating activities               1,986         1,705              4,481
                                                ---------    ----------         ----------
Investing activities
- --------------------

Increase in marketable securities                    (51)         7,711                 -
Purchases of tangible fixed assets                    (2)           (10)              (206)
                                                ---------    ----------         ----------

Cash used in investing activities                    (53)         7,701               (206)
                                                ---------    ----------         ----------
Financing activities
- --------------------

Dividends paid to shareholders                     (2,804)       (11,548)               -  
                                                ---------    ----------         ----------

                                                   (2,804)       (11,548)               - 
                                                ---------    ----------         ----------

Increase (decrease) in cash and cash                                                      
equivalents                                         (871)        (2,142)             4,275
                                                =========      =========          ========

Summary
- -------
Increase in cash and cash equivalents               (871)        (2,142)             4,275
Cash and cash equivalents at beginning
of year                                             5,797         4,926              2,784
                                                 --------      --------           --------

Cash and cash equivalents at end of
year                                                4,926         2,784              7,059
                                                 ========      ========           ========
Supplemental disclosures of cash flow
information:
Cash paid during the year for:
Interest                                               -             -                  - 
Income taxes                                          694           249                550
</TABLE>
<PAGE>   12
                                                                   June 10, 1996
Mutarestes B.V.                                                        Page 9/13
at Heerhugowaard                                            3457202-1995-637bf-4



NOTES TO THE CONSOLIDATED FINANCIAL STATEMENTS


DESCRIPTION OF BUSINESS
- -----------------------
Mutarestes' operating company Pluripharm International has a primary business
of wholesale distribution of medicines.  The companies' customers are primarily
located in the Netherlands.  The companies' products are readily available and
the company is not dependent on a single supplier or a few suppliers.


GENERAL ACCOUNTING PRINCIPLES
- -----------------------------
The financial statements of Mutarestes B.V. have been prepared under the
historical cost convention.


PRINCIPLES OF CONSOLIDATION
- ---------------------------
The financial statements of Mutarestes B.V. and its wholly-owned subsidiaries
have been included in the consolidation.  The consolidated financial statements
are prepared in accordance with the accounting principles as applied to
Mutarestes B.V. which are substantially the same as US-Generally accepted
accounting principles (US-GAAP).  Included in the consolidation are: 
- - Pluripharm International B.V. (Krommenie, The Netherlands) 
- - B.V. Financieringsmaatschappij De Nieuwe Wereld (Amsterdam, The Netherlands) 
All significant intercompany profits, transactions and balances have been
eliminated upon consolidation.


PRINCIPLES FOR THE VALUATION OF ASSETS AND LIABILITIES  
- ------------------------------------------------------


ASSETS AND LIABILITIES

Current assets

Cash and cash equivalents
- -------------------------
Cash equivalents consist primarily of highly liquid investments, such as bank
deposits, with insignificant interest rate risk and original maturities of
three months or less on the date of acquisition.

Accounts receivable-trade
- -------------------------
The accounts receivable-trade are recorded at face value.
<PAGE>   13
                                                                   June 10, 1996
Mutarestes B.V.                                                       Page 10/13
at Heerhugowaard                                            3457202-1995-637bf-4


Inventory
- ---------
Inventory is stated at the lower of cost (first-in, first-out method) or market
value.
Cost includes the net prices paid for materials purchased and freight
charges for freight.


Tangible fixed assets
- ---------------------
The tangible fixed assets of the subsidiaries have been valued at cost less
depreciation.
Depreciation is based on the estimated useful lives of the
corresponding assets and is calculated by applying fixed percentages to their
historical cost or historical book value.

The estimated useful lives are:
- - cars                              4 years
- - furniture and equipment         4-5 years


Other assets and liabilities
- ----------------------------
Other assets and liabilities are stated at face value, unless otherwise
mentioned in the notes to the accounts.  An evaluation of the fair market value
of the Company's debt and other liabilities does not result in a value
significantly different from face value.


Income taxes
- ------------
The Company's income tax liability has been determined under the provisions of
Statement of Financial Accounting Standards No.109 - Accounting for Income
Taxes.  There are no net operating losses carried forward or temporary
differences between the book carrying amounts and the tax basis of assets and
liabilities at the relevant balance sheet date.  If any of these two elements
occurs in the future a deferred tax amount will be calculated at the enacted
rate of taxation in The Netherlands.


PRINCIPLES FOR DETERMINATION OF FINANCIAL RESULTS
- -------------------------------------------------
The results are determined as the difference between sales and cost of sales
after deduction of the expenses for the year, calculated on the basis of the
aforementioned valuation principles.  Revenues from sales are recognized upon
shipment.


Sales

Sales consist of the revenue of goods and services supplied exclusive of VAT.
<PAGE>   14
                                                                   June 10, 1996
Mutarestes B.V.                                                       Page 11/13
at Heerhugowaard                                            3457202-1995-637bf-4


Use of estimates

The preparation of the Company's consolidated financial statements in
conformity with generally accepted accounting principles necessarily requires
Management to make estimates and assumptions that affect the amounts of assets
and liabilities reported and disclosure of contingent assets and liabilities at
the balance sheet dates and the amounts of revenue and expense reported during
the fiscal year.  Actual results could differ from these estimates.
<PAGE>   15
                                                                   June 10, 1996
Mutarestes B.V.                                                       Page 12/13
at Heerhugowaard                                            3457202-1995-637bf-4


NOTES TO SPECIFIC ITEMS OF THE FINANCIAL STATEMENTS


1 Tangible fixed assets

The accumulated depreciation amounts to Dfl 123,232 as of December 31, 1994 and
Dfl 68,448 as of December 31, 1995.


2 Payable to shareholders

<TABLE>                      
<CAPTION>                    
                                           1994              1995
                                      ---------         ---------
                                            DFL               DFL
 <S>                                  <C>               <C>
 Dividend 1994                        1,597,259         1,597,259
 Dividend 1995                                -         2,000,000
                             
 Return of paid-up           
 share capital                                -            88,000
                                      ---------         ---------
                             
                                      1,597,259         3,685,259
                                      =========         =========
                             
 3 Other liabilities         
  
                             
                                           1994              1995
                                       --------          --------
                                            DFL               DFL

 Payable to customers                 4,285,197         5,918,923
                             
 Other                                   32,467            44,180
                                      ---------         ---------
                             
                                      4,317,664         5,963,103
                                      =========         =========
</TABLE>

The amount payable to customers are volume-discounts which are payable
annually.  A separate agreement has been made regarding these discounts, which
does not allow customers to offset amounts payable to the company by such
discounts.


4 Shareholders' equity

During 1995 the legal structure of the Company changed from a Dutch N.V.
(public limited) into Dutch B.V. (private limited company).  This change of
legal structure was followed by a repayment of paid-up share capital and a
change of the nominal value of the shares.  As of December 31, 1995 the issued
and fully paid-up share capital is Dfl 40,000.
<PAGE>   16
                                                                   June 10, 1996
Mutarestes B.V.                                                       Page 13/13
at Heerhugowaard                                            3457202-1995-637bf-4


5 Sales

The sales are entirely realized in the Netherlands.  No single customer
accounted for more than 10% of the company's sales in 1995, 1994 or 1993.


6 Contingent liabilities

Lease commitments involve an amount of Dfl 4,124 per month.  The contract can
be cancelled taking into account a four month notice.  The lease commitment for
1996 will be Dfl 49,500, 1997 Dfl 49,500, 1998 Dfl 49,500, 1999 Dfl 49,500,
2000 and following years Dfl 49,500 each year.  The company and its
subsidiaries constitute a fiscal entity for corporate income taxes.  Both the
company and its subsidiaries are liable for obligations which result from this
fiscal entity.


7 Subsequent events

Due to regulation of the Dutch Department of Health the selling prices of
pharmaceuticals decreased significantly as of June 1, 1996.  Currently
management is not able to estimate the effect of this regulation, although
management does not expect no significant decrease of the gross margin, since
the majority of the price change will be transferred to the suppliers.
<PAGE>   17
                                EUROMED, INC.
              PRO FORMA CONDENSED COMBINED FINANCIAL INFORMATION
                                 (UNAUDITED)

        In July 1996, EuroMed, Inc. (EuroMed) acquired all the outstanding
shares of Mutarestes B.V. (Mutarestes), a wholesale distributor of medicines in
the Netherlands, for $5,857,00 cash and 850,000 shares of EuroMed. The
acquisition of Mutarestes will be accounted for by EuroMed as a purchase
whereby the basis for accounting for the Mutarestes assets and liabilities will
be based upon their fair market values at the date of the acquisition.

        The unaudited Pro Forma Condensed Combined Statement of Operations (Pro
Forma Income Statements) for the year ended December 31, 1995 and the six
months ended June 30, 1996 give pro forma effect to the acquisition of
Mutarestes (and other adjustments as described in the accompanying notes) as if
it had occurred on January 1, 1995. The Pro Forma Income Statements are based
on the historical results of operations of EuroMed and Mutarestes for the year
ended December 31, 1995 and the six months ended June 30, 1996. The Pro Forma
Condensed Combined Balance Sheet as of June 30, 1996 (Pro Forma Balance Sheet)
gives pro forma effect to the acquisition of Mutarestes as if it had occurred
on that date. The Pro Forma Income Statements and the Pro Forma Balance Sheet
and the accompanying notes (Pro Forma Financial Information) should be read in
conjunction with and are qualified by the historical financial statements of
EuroMed included in its Form 10-K for the year ended December 31, 1995 and Form
10-Q for the quarter ended June 30, 1996, and the historical financial
statements of Mutarestes and notes thereto appearing elsewhere herein.


The Pro Forma Information is intended for informational purposes only and is
not necessarily indicative of the future position or results of operations of
EuroMed after the acquisition of Mutarestes, or the financial position or the
results of operations of EuroMed that would have actually occurred had the
acquisition of Mutarestes been effected as of the date or for the periods
presented.
<PAGE>   18
                                 EuroMed, Inc.
            Pro Forma Condensed Combined Balance Sheet (Unaudited)
                              As of June 30, 1996

<TABLE>
<CAPTION>
                                                                                            Euromed
                                                Euromed     Mutarestes     Pro forma      Inc. on a pro
                                                  Inc.       B.V. (A)      adjustments     forma basis
                                                -------     ----------    -----------     -------------
                                                                   (in thousands)
<S>                                            <C>          <C>           <C>             <C>
Assets

Current Assets:
Cash and cash equivalents                        3,426         1,518                            4,944
Trade accounts receivable                        1,421         3,754           (108) (B)        5,067
Loan receivable                                    710            --                              710
Due from affiliated                                                                                   
companies and other                                                                                  
related parties                                    536            --                              536
Inventory                                        5,162         1,421                            6,583
Other receivables and                                                                                
prepaid expenses                                   275           359                              634
Total current assets                            11,530         7,052           (108)           18,474
Tangible fixed assets                              382            87                              469   
Intangible assets                                  539            --         10,796 (C)        11,335
                                                ------        ------         ------            ------
Total assets                                    12,451         7,139         10,688            30,278
                                                ======        ======         ======            ======
                                                                                                     
Liabilities                                                                                          
                                                                                                     
Current Liabilities                                                                                  
                                                                                                     
Loan payable                                       293            --                              293
Bank overdraft                                                                                       
Trade accounts payable                           3,963         2,647           (108) (B)        6,502
Taxes payable                                      530           893                            1,423
Due to affiliated companies                                                                           
controlling interests and                                                                            
other related parties                                8            --                                8
Other payables and accrued                                                                           
expenses                                           247         2,686          5,857  (C)        8,790
Total current liabilities                        5,041         6,226          5,749            17,016
Long term debts                                    146            --                              146
                                                                                                     
Shareholders equity                              7,264           913          4,939            13,116
                                                                   0                                  
                                                                   0                                 
                                                ------        ------         ------            ------
Total liabilities and 
stockholders equity                             12,451         7,139         10,688            30,278
                                                ======        ======         ======            ======
</TABLE>
<PAGE>   19
                        EUROMED, INC. AND SUBSIDIARIES
                     NOTES TO THE PRO FORMA BALANCE SHEET
                                 (UNAUDITED)


(A)     Represents the historical balance sheet information of Mutarestes. The
        financial position of Mutarestes as of June 30, 1996 was translated 
        into US dollars using the exchange rate as of June 30, 1996 of 
        Dfl 1.7075 = US$1.00.

(B)     Represents the elimination of intercompany balances between EuroMed and
        Mutarestes.

(C)     Adjusts the assets acquired and liabilities assumed in the acquisition
        of Mutarestes to reflect the allocation of the estimated purchase
        price. The resulting goodwill was calculated as follows:


<TABLE>                                                        
        <S>                                                  <C>       
        Estimated purchase price:                        (in thousands)
                Amount paid to be paid in cash                5,857    
                Issuance of 850,000 shares of EuroMed                  
                  with a fair market value at the date of              
                  acquisition of $6.75 per share              5,737    
                Direct costs of acquisition                     115    
                                                             ------    
                                                             11,709    
        Less assets acquired:                                          
                Current assets                                7,052    
                Other assets                                     87    
                                                                       
        Plus liabilities assumed:                                      
                Current liabilities                           6,226    
                                                             ------    
                                                             10,796    
                                                             ======    
                                                                       
</TABLE>                                                       


<PAGE>   20
                                 EUROMED INC.
                     PRO FORMA CONDENSED INCOME STATEMENT
                         YEAR ENDED DECEMBER 31, 1995
                                 (UNAUDITED)



<TABLE>
<CAPTION>
                                                                   Euromed
                         Euromed     Mutarestes     Pro forma      Inc. on a pro
                         Inc.        b.v. (A)       adjustments    forma basis
                         -------     ----------     -----------    -------------
                                 (in thousands, except per share data)
<S>                      <C>         <C>            <C>            <C>
Sales                   32,978      31,539          (2,914) (B)    61,603
Cost of goods sold      29,622      28,962          (2,914) (B)    55,670
                                              
Gross profit             3,356       2,577                          5,933
                                                                         
                                                                         
Selling, general and                                   540  (C)
administrative expenses  2,100         473             249  (F)     3,362
                                         0                               
                         1,256       2,104            (789)         2,571
                                                                         
Interest (net)             (48)         56                              8
                                                                         
Income before income
taxes                    1,208       2,160            (789)         2,579
                                                                         
                                                                         
Income taxes               372         755             (87) (D)     1,040
                         -----      ------           -----         ------
Net income                 836       1,405            (702)         1,539
                         =====      ======           =====         ======
Pro forma earnings 
per share                                                            0.38
                                                                   ======
Average shares                                                      4,000 (E)
                                                                   ======


</TABLE>
<PAGE>   21
                                EUROMED, INC.
                PRO FORMA CONDENSED COMBINED INCOME STATEMENT
                        SIX MONTHS ENDED JUNE 30, 1996
                                 (UNAUDITED)



<TABLE>
<CAPTION>

                        Euromed    Mutarestes    Pro forma     Euromed
                        Inc.       b.v. (A)      adjustments   Inc on a pro  
                                                               forma basis
                        -------------------------------------
                        (in thousands, except per share data)

<S>                     <C>        <C>           <C>           <C>
Sales                   17,876     17,704        (1,798) (B)   33,782
Cost of goods sold      16,185     16,177        (1,798) (B)   30,564
                        ------     ------        ------        ------
                                                                     
Gross profit             1,691      1,527            --         3,218
                                                                     
                                                                     
Selling, general and
administrative expenses  1,091        373           270 (C)     1,734
                                                                     
                           600      1,154          (270)        1,484
                                                                     
Interest (net)             (48)        28                         (20)
                                                                     
Income before income
taxes                      552      1,182          (270)        1,464
                                                                     
                                                                     
Income taxes               189        427                         616
                        ------     ------        ------        ------
Net income                 363        755          (270)          848
                        ======     ======        ======        ======
Pro forma earnings 
per share                                                        0.21
                                                               ======
Average shares                                                  4,000(E)
                                                               ======



</TABLE>


<PAGE>   22
                        EUROMED, INC. AND SUBSIDIARIES
                   NOTES TO THE PRO FORMA INCOME STATEMENT
                                 (UNAUDITED)

(A)     Represents the historical income statement information of Mutarestes. 
        The results of operations of Mutarestes for the year ended December 31,
        1995 were translated into US dollars using the average exchange rate
        for the year ended December 31, 1995 of Dfl 1.6064 = US$1.00. The
        results of operations of Mutarestes for the six months ended June 30,
        1996 were translated into US dollars using the average exchange rate 
        for the six months ended June 30, 1996 of Dfl 1.6740 = US$1.00.

(B)     Represents the elimination of intercompany transactions between EuroMed
        and Mutarestes.

(C)     Represent the amortization of goodwill on a straight line basis over 20
        years.

(D)     Represents the income tax adjustments related to the pro forma 
        adjustments.

(E)     Adjusted to reflect the issuance of 1,150,000 shares in the initial
        public offering that occurred in March 1996 and the 850,000 shares
        issued in the acquisition of Mutarestes as if it occurred in the
        beginning of fiscal year 1996 and 1995, respectively.

(F)     As of January 1, 1996, the management of Mutarestes receives a
        management fee (included in the income statement ended June 30, 1996).
        For comparison reasons a pro forma adjustment in 1995 has been made.

<PAGE>   23
                                   SIGNATURES


         Pursuant to the requirements of the Securities Exchange Act of 1934,
Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                        EUROMED, INC.
                                        
                                        
                                        
Date:  October 9, 1996                      By:  /s/ JAN BOUWMAN
                                                 ------------------------------
                                                 Jan Bouwman
                                        
                                                 Chief Financial Officer, 
                                                 Secretary & Treasurer
                                        
                                        



                                       4
<PAGE>   24
                               INDEX TO EXHIBITS

<TABLE>
<CAPTION>
                 Exhibit No.                                Description
                 -----------                                -----------
                    <S>                      <C>
                    2.1                      Stock Purchase Agreement dated as of June 19, 1996, by and among
                                             Registrant, Purchaser, Doets, Roozekrans, Mutarestes, Pluripharm and
                                             FDNW.(4)
                   
                    2.2                      Stock Purchase Agreement, dated as of June 19, 1996, by and among
                                             Registrant, Purchaser, Doets and Roozekrans.(1)
                   
                    4.1                      Restated Articles of Incorporation of the Company.(2)
                   
                    4.2                      Bylaws of the Company.(2)
                   
                    4.3                      Specimen of Common Stock Certificate.(3)
                   
                    10.1                     Consulting, Management and Noncompetition Agreement, dated as of July
                                             5, 1996, by and between Purchaser and Doets.(1)
                   
                    10.2                     Consulting, Management and Noncompetition Agreement, dated as of July
                                             5, 1996, by and between Purchaser and Roozekrans.(1)
                   
                    10.3                     Consulting, Management and Noncompetition Agreement, dated as of July
                                             5, 1996, by and between Purchaser and Hinnen.(1)
                   
</TABLE>

- ------------------------------

         (1)     Filed herewith.


         (2)     Previously filed as an exhibit to Registration No. 33-80801 on
                 Form S-1 and incorporated herein by reference.

         (3)     Previously filed as an exhibit to Amendment No. 1 to
                 Registration No. 33-80801 on Form S-1 and incorporated herein
                 by reference.

         (4)     Previously filed.





                                       5

<PAGE>   1
                                                                     EXHIBIT 2.2


                            STOCK PURCHASE AGREEMENT


This Stock Purchase Agreement (the "Agreement"), dated as of June 19, 1996, by
and among Dr. A. Doets ("Doets"), Dr. N. Th.P. Roozekrans ("Roozekrans")
(Doets and Roozekrans together hereinafter "the Shareholders"), EuroMed Europe
B.V., a Netherlands corporation ("Purchaser") and wholly-owned subsidiary of
EuroMed, Inc., a Nevada corporation ("EurOMed") and EuroMed.

W I T N E S S E T H:

WHEREAS, Shareholders hold together all of the issued and outstanding shares of
capital stock ("the Stock") of the Netherlands corporation Nydima B.V.
("Nydima") and N.T.P. Consult B.V. ("Consult") (Nydima and Consult together
also referred to as the "Companies"), which together hold all of the issued and
outstanding stock of the Netherlands corporation Mutarestes B.V.
("Mutarestes"), which in turn owns all of the issued and outstanding stock of
Pluripharm International B.V. ("Pluripharm"), which in turn owns all of the
issued and outstanding stock of De Nieuwe Wereld B.V. ("DNW") (Mutarestes,
Pluripharm and DNW together hereinafter to be referred to as the
"Subsidiaries"), and the Shareholders desire to sell and Purchaser desires to
purchase the Stock;

WHEREAS, this Agreement sets forth the conditions subject to which Purchaser
will purchase from the Shareholders all of the Stock;
<PAGE>   2
                                     - 2 -




WHEREAS, in addition to this Agreement the Shareholders have in a separate
agreement (the Pluripharm Stock Purchase Agreement) agreed to sell to
Purchaser, by means of the present sale of the Companies, the stock in the
Subsidiaries;

WHEREAS, the Shareholders have personally assumed certain liabilities vis-a-vis
Purchaser and Purchaser and EuroMed have accepted certain liabilities vis-a-vis
the Shareholders as set out in the Pluripharm Stock Purchase Agreement in
relation to the Subsidiaries.

NOW, THEREFORE, in consideration of the mutual representations, warranties and
covenants herein contained, and on the terms and subject to the conditions
herein set forth, the parties hereto hereby agree as follows:

ARTICLE 1                 PURCHASE OF THE STOCK

1.1      Subject to the terms and conditions contained herein and the
         conditions precedent included in the Pluripharm Stock Purchase
         Agreement, Purchaser agrees to purchase the Stock from the
         Shareholders, and the shareholders agree to sell the Stock to
         Purchaser at the Closing (as defined in the Pluripharm Stock Purchase
         Agreement).
<PAGE>   3
                                     - 3 -



1.2      The Stock consists of 40 shares with a par value of NLG 1,000 in the
         capital stock of each of Nydima and Consult, which shares represent
         all of the outstanding stock of Nydima and Consult.

ARTICLE 2                 PURCHASE PRICE

The purchase price amounts to the aggregate of:

- -        NLG 10,000,000;

- -        850,000 shares of EuroMed stock with a par value of $0.01;

- -        the intrinsic value of the Stock decreased with the value of the
         Subsidiaries as such value appears from the balance statement of the
         Companies per 1 July 1996.


ARTICLE 3                 THE PLURIPHARM STOCK PURCHASE AGREEMENT

3.1      In addition to the present agreement the parties have entered in the
         Pluripharm Stock Purchase Agreement, which agreement sets out the
         terms and conditions agreed between the parties in respect of the
         Subsidiaries.
<PAGE>   4
                                     - 4 -



ARTICLE 4                 CLOSING

4.1      At the Closing:

         -       the Shareholders will deliver the Stock to Purchaser, by means
                 of the execution of a notarial deed to be executed by civil
                 law notaries Van Apeldoorn/Taselaar at Ede, the Netherlands,

         -       the purchase price will be paid and the EuroMed Stock will be
                 delivered to the Shareholders; such other actions will be
                 taken as have been agreed in the Pluripharm Stock Purchase
                 Agreement and as will be necessary to complete the
                 transactions envisaged by this Agreement and the Pluripharm
                 Stock Purchase Agreement.

ARTICLE 5                 REPRESENTATIONS AND WARRANTIES

5.1      With respect to the Subsidiaries the Shareholders make such
         representations and warranties as have been set out in the Pluripharm
         Stock Purchase Agreement,

5.2      With respect to the companies the Shareholders make such
         representations and warranties and such promises to Purchaser as will
         be required from Purchaser by B.V. Holding Maatschappij "De Hondsrug"
         under paragraphs 3, 4, 5 and 6.5 of the draft
<PAGE>   5
                                     - 5 -



         "overeenkomst tot koop en verkoop van registeraandelen", which is
         attached as Schedule 1 hereto.

ARTICLE 6                 INDEMNIFICATION

The indemnification clauses in the Pluripharm Stock Purchase Agreement apply
equally to this Agreement, be it that in respect of the representations,
warranties and promises made by the Shareholders with respect to the Companies,
the restrictions of Article 12.03.(d) of the Pluripharm Stock Purchase
Agreement do not apply.

ARTICLE 7                 ACKNOWLEDGEMENT

7.1      The parties acknowledge that the structure of the present transaction
         is favoured by Doets and Roozekrans and has been chosen on their
         request. Accordingly the Purchaser has agreed to acquire indirectly
         the stock in the Subsidiaries by means of acquiring the stock in the
         Companies, under the assumption that it will be able to sell and
         transfer immediately upon completion of the present transaction the
         Stock in the Companies at the intrinsic value thereof, after having
         arranged for the divestment of the Subsidiaries by the Companies.
<PAGE>   6
                                     - 6 -



7.2      It is acknowledged that any additional costs resulting from the fact
         that the structure favoured by Doets and Roozekrans has been chosen
         will be charged to Doets and Roozekrans and Doets and Roozekrans
         undertake to reimburse Purchaser for such additional costs.

ARTICLE 8                 CONSENT AS REFERRED TO IN ARTICLE 1:88 OF THE DUTCH
                          CIVIL CODE

8.1      By undersigning this Agreement the spouses of Doets and Roozekrans
         hereby consent to Doets and Roozekrans entering into the present
         transactions and to the entering into by Doots and Roozekrans of the
         obligations and the making of the representations and warranties as
         mentioned therein, such obligations including indemnification and hold
         harmless provisions.

ARTICLE 9                 PHARDIS

9.1      The parties acknowledge that Doets and Roozekrans each hold 20% shares
         in the capital stock of the Netherlands corporation Phardis B.V.
         Purchaser and EuroMed do not object to such shareholding.
<PAGE>   7
                                     - 7 -



9.2      Doets and Roozekrans will consult with Purchaser before taking any
         action in respect of their shares in Phardis B.V., such action to
         include the sale of and the voting on such shares.

ARTICLE 10                ENTIRE AGREEMENT

10.1     This Agreement, together with the Pluripharm Stock Purchase Agreement
         supersedes all previous agreements and understandings between the
         parties concerning the subject matter thereof (including the letter of
         intent dated 7 May, 1996 and the amendment thereto dated 23 May, 1996)
         and constitutes the entire agreement between the parties with respect
         to the subject matter thereof.

ARTICLE 11                CHOICE OF LAWS

11.1     This Agreement and the rights and obligations of the parties hereto
         are governed by and construed and enforced in accordance with the
         substantive laws of the Netherlands. Any dispute arising under this
         Agreement shall be exclusively settled by the competent Court of
         Arnhem, the Netherlands.

ARTICLE 12                NO RESCISSION
<PAGE>   8
                                     - 8 -



12.1     All parties waive their rights to rescind the Agreement,

ARTICLE 13                TERMINATION

13.1     This Agreement shall automatically terminate upon the termination of
         the Pluripharm Stock Purchase Agreement,


ARTICLE 14                GUARANTEE OF EUROMED

14.1     EuroMed guarantees the proper performance by Purchaser of its
         obligations under this Agreement.


IN WITNESS WHEREOF, the parties hereto have duly executed this Agreement as of
the date first written above,


- -----------------------------------------
Dr. A. Doets




- -----------------------------------------
Dr. N. Th.P. Roozekrans
<PAGE>   9
                                     - 9 -






- -----------------------------------------
EuroMed Europe B.V.




- -----------------------------------------
EuroMed, Inc.


For consent in accordance with Article 1:88 Dutch Civil Code




- --------------------------------------     -------------------------------------
spouse Mr. A. Doets                        spouse Mr. N. Th.P. Roozekrans

<PAGE>   1
                                                                    EXHIBIT 10.1


Doc 2/

                            ref.: MS/MANAGEMENT.USU

                              MANAGEMENT AGREEMENT

The undersigned:

1.       the closed corporation EUROMED EUROPE B.V., with registered office in
         Oosterhout, legally represented in this matter by its statutory
         director B.V. Wisteria, (hereafter called: "EuroMed B.V.");

2.       the closed corporation in formation USUS NOTUS B.V. i.o., with
         registered office in Westzaan, legally represented in this matter by
         its organizer, Mr. A. Doets, (hereafter called: "Usus");

3.       a.      the closed corporation MUTARESTES B.V., with registered office
                 in Heerhugowaard, legally represented in this matter by its
                 statutory directors, Mr. A. Doets and Mr. N. Th. P.
                 Roozekrans, (hereafter called: "Mutarestes");

         b.      the closed corporation PLURIPHARM INTERNATIONAL B.V., with
                 registered office in Heerhugowaard, legally represented in
                 this matter by its statutory director, Mutarestes, (hereafter
                 called: "Pluripharm");

         c.      the closed corporation FINANCIERINGSMAATSCHAPPIJ DE NIEUWE
                 WERELD B.V., with registered office in Heerhugowaard, legally
                 represented in this matter by its statutory director,
                 Mutarestes, (hereafter called: "DNW");

         Parties numbered 3.a. through 3.c. hereafter also indicated as: "the
         Corporations"

TAKING INTO CONSIDERATION:

a.       EuroMed B.V., as 100% subsidiary of the corporation under the laws of
         the state of





                                       11
<PAGE>   2
         Nevada, United States, EUROMED INC. ("EuroMed"), is the Netherlands
         holding company of EuroMed's operating companies;

b.       EuroMed B.V. holds 100% of the shares in the closed corporations
         Confedera B.V. ("Confedera") and Galenica B.V.  ("Galenica") and 100%
         of the shares in Mutarestes, which corporation in turn holds 100% of
         the shares in Pluripharm, which corporation in turn holds 100% of the
         shares in DNW;

c.       Confedera, Galenica, and Pluripharm are the operating companies within
         the EuroMed group which engage in the wholesaling of medicines;

d.       EuroMed B.V. wishes to ensure, by entering into management agreements,
         that executives are available who are responsible for the daily
         management of its operating companies during a specified time;

e.       In that connection, Usus is prepared and able to fulfill this need for
         the benefit of Mutarestes and its subsidiaries Pluripharm and DNW, by
         making a qualified executive available to Mutarestes on the following
         conditions;

HAVE AGREED AS FOLLOWS:

Article 1 Activities

1.1      For the duration of this agreement (the "Agreement"), Usus shall make
         a manager available to Mutarestes, i.e.  Mr. A. Doets (hereafter
         called: "Manager"). Mutarestes states that it agrees to this Manager
         and to let him perform the activities which are specified in the
         Agreement.

1.2      In the event that the Manager, for whatever reason, cannot perform his
         activities, Usus can propose a replacement manager to Mutarestes.
         Mutarestes shall inform Usus within





                                       12
<PAGE>   3
         one week in writing whether it agrees to the proposed replacement.

1.3      If it should be necessary for Mutarestes' conduct of business, EuroMed
         B.V. shall consult with Usus if it is of the opinion that the nature
         of the Manager's activities should be adjusted.

1.4      In view of the fact that the Manager is made available to Mutarestes
         by Usus, the parties recognize expressly that the Manager is not in
         the employ of Mutarestes, nor can be considered in any manner as an
         employee of Mutarestes.

1.5      For the execution of its activities, Usus shall be named a statutory
         director of Mutarestes, which corporation during the duration of this
         Agreement shall continue to function as a statutory director of
         Pluripharm and DNW.  With regard to its activities as statutory
         director, NTP shall be represented by the Manager, or by his
         replacement.

1.6      Mutarestes pledges to grant to the Manager that authority and
         cooperation which are required for the proper performance of his
         activities.

Article 2 Compensation

2.1      Mutarestes shall compensate Usus for its activities f 200,000 per
         year, excluding value added tax. Mutarestes shall pay the compensation
         in four equal installments per year. Usus shall send an invoice to
         Mutarestes once per quarter in which the activities of the Manager are
         also explained. Mutarestes shall pay the invoice within 30 days.

         It shall be further agreed among EuroMed B.V. and the Corporations, to
         which of the Corporations the payment obligations arising from the
         Agreement shall be charged.

2.2      Usus shall see to strict compliance with all obligations incumbent
         upon it with regard to added tax and with regard to payroll tax and
         social insurance premiums relating to the





                                       13
<PAGE>   4
         Manager. Usus shall indemnify Mutarestes with regard to all possible
         claims by the tax authorities and/or the trade association against
         Mutarestes in the event that they should take the position that
         Mutarestes has a withholding or payment obligation with regard to the
         Manager for payroll tax and/or social insurance premiums, including
         increases, fines and interest.

2.3      If the Manager for whatever reason, during a period longer than two
         weeks, cannot perform any activities for Mutarestes and no appropriate
         replacement is provided, Mutarestes shall be released from its
         obligation for payment of the compensation, effective the third week,
         for the duration of the default, with the exception of compensation
         for reasonably incurred expenses which have occurred despite the
         absence of the Manager and which can no longer be reversed, provided
         these expenses fall within the ordered activities.

Article 3 Duration of the Agreement

3.1      The Agreement shall take effect retroactively as of 1 January 1996 for
         a period of 5 years and shall therefore terminate by action of law on
         31 December 2000, without a requirement for any further action of the
         parties.

3.2      Extension of the Agreement shall only be possible if the parties
         decide on it in writing.

3.3      EuroMed B.V. and Usus can each cancel the Agreement in the interim,
         with observance of a notice period of 6 months. Cancellation shall
         occur by means of a registered letter addressed to the management of
         the other party.

3.4      The Agreement can be cancelled with immediate effect if:

         a.      Usus or Mutarestes is declared bankrupt or if suspension of
                 payment is granted to Usus or Mutarestes;





                                       14
<PAGE>   5
         b.      the Manager dies, is declared bankrupt or the Manager is
                 granted suspension of payment or, in the event of illness or
                 otherwise during a period of three consecutive months, the
                 Manager has not been able, for more than thirty-five days, to
                 fulfill the obligations of article 1 and Mutarestes has not
                 accepted Usus' offer pursuant to article 1.2.

3.5      Usus and Mutarestes shall have the authority to dissolve the Agreement
         if a party to the Agreement does not comply with, or comply with on
         time, or properly comply with, an obligation from the Agreement.

Article 4 Liability

4.1      Usus and the Manager shall not be liable to Mutarestes, as well as to
         third parties, for damage which arises from the action or failure to
         act of the Manager, performed within the formal sphere of his
         authority, without prejudice to liability which arises from the
         intentional or gross fault of Usus and/or the Manager.

4.2      Mutarestes releases Usus and the Manager in the event of liability of
         Usus and/or the Manager to third parties for actions or failure to act
         of the Manager, performed within the formal sphere of his authority,
         unless the liability arises from the intentional or gross fault of
         Usus and/or the Manager.

Article 5 Competition clause

5.1      Neither Usus nor its direct or indirect shareholder shall, during the
         period from the effective date of the Agreement until five years after
         the termination of the Agreement, conduct any activity, direct or
         indirect, by means of a legal entity or otherwise, alone or in
         cooperation with others, within the Benelux, which in any manner could
         be in competition with the activities of Mutarestes, other than
         activities with regard to having pharmacies. Neither Usus nor its
         direct or indirect shareholder shall make any





                                       15
<PAGE>   6
         investments in competing companies. Interests existing at the time of
         entering into this Agreement can be maintained.

5.2      Upon violation of the competition clause in article 5.1, Usus shall
         owe a fine of f 1,000,000 per violation, with an increase of f 10,000
         per day that the violation continues after notice of default. The
         Manager shall be jointly and severally liable with Usus for this fine.

Article 6 Confidentiality requirement

6.1      Usus shall observe strict confidentiality during the period of the
         Agreement and thereafter regarding all that which it shall learn
         regarding the business and interests of Mutarestes and the companies
         connected with Mutarestes, including particularly (but not limited to)
         knowledge regarding the pricing used by Pluripharm and discounts and
         relationships with customers.

6.2      Usus shall be required to impose this confidentiality requirement upon
         the Manager and his replacements unabridged.

6.3      Regardless of the manner in which this Agreement is terminated, Usus
         shall return all property of the Corporations to the Corporations,
         including (but not limited to) all data carriers, copies, books and
         documents which contain data from the Corporations.

Article 7 Obligation of the Manager

7.1      Usus shall guarantee that the provisions of articles 5, 6 and 8 shall
         be correspondingly applicable to the Manager. As a sign of his
         agreement to be bound by these articles, the Manager shall co-sign the
         Agreement.

Article 8 Intellectual property





                                       16
<PAGE>   7
8.1      The intellectual property rights with regard to new products developed
         during the period of the Agreement by or in cooperation with Usus
         shall rest with Pluripharm and, insofar as necessary, Usus shall
         transfer these unconditionally to Pluripharm and they shall be
         unconditionally accepted by Pluripharm.

8.2      Usus shall not in any manner, directly or indirectly, by means of
         legal entities or otherwise, make use of the industrial property
         rights which have been in the past or are now used by Pluripharm for
         the conduct of Pluripharm's business.

Article 9 Invalid provisions

9.1      If one or more articles of the Agreement should be invalid or in
         another manner not binding, the validity of the remaining articles of
         the Agreement shall not thereby be affected. The parties shall then
         adjust the Agreement in mutual consultation, such that the non-binding
         articles shall be replaced by other provisions which differ as little
         as possible from the relevant non-binding articles.

Article 10 Applicable law and choice of forum

Netherlands law shall be applicable to the Agreement. Any dispute which shall
arise from the Agreement shall be subject exclusively to judgment by the
authorized court in the District of Arnhem.

Article 11       Supplementary clauses

11.1     The Corporations accept joint and several liability for the payment
         obligations of Mutarestes under the Agreement.

11.2     In the performance of the management activities, the reasonable
         interests of the other operating companies of EuroMed B.V. will
         continually be observed, such that the activities to be performed in
         respect of the Agreement shall not be damaging to the other





                                       17
<PAGE>   8
         operating companies.

11.3     a.      The Manager shall agree to consult regularly, but at least
                 once a month, with the management of Galenica and Confedera
                 regarding the state of affairs within the Corporations and the
                 policy to be carried out regarding the Companies.

11.3     b.      Usus shall annually, at the latest on 1 December of a fiscal
                 year, develop a business plan in consultation with and for the
                 approval of the management of Galenica and Confedera, in which
                 the commercial objectives for the Corporations for the
                 following fiscal year shall be established (the "Business
                 Plan").

11.3     c.      During a fiscal year, Usus shall carry out management and
                 policy with regard to the Corporations as much as possible in
                 accordance with the Business Plan.

11.3     d.      If and insofar as Usus notices that the actual developments of
                 the Corporations are going to deviate from the Business Plan,
                 Usus shall notify the management of Galenica and Confedera of
                 this as quickly as possible. Then, in mutual consultation,
                 measures to be taken shall be decided on and, if necessary,
                 the Business Plan for the relevant year shall be modified.

11.4     Manager accepts that, with regard to the actions named below
         concerning the Corporations, the express approval of the management of
         Galenica and Confedera shall be required: 

         a.      any substantial and/or fundamental change in the conduct of 
                 business of the relevant Corporation, such as change in the 
                 distribution and/or production strategy; 

         b.      contracting with or dismissal of employees, or the adjustment 
                 or changing of conditions of employment, other than providing 
                 for the replacement of existing employees; 

         c.      changing of bank relationships or of the conditions thereof 
                 which have already





                                       18
<PAGE>   9
                 been entered into by the relevant corporation;

         d.      entering into transactions which exceed the amount of f
                 100,000; 

         e.      settling any claim which exceeds the amount of f
                 30,000; 

         f.      acquiring or disposing of investments in other
                 corporations.

11.5     EuroMed B.V. agrees not to make any change in the statutory management
         of the Corporations during the period of this Agreement.

11.6     EuroMed B.V. agrees, in its capacity of sole shareholder of
         Mutarestes, that this Agreement shall be signed on behalf of
         Mutarestes by its statutory directors A. Doets and N. Th. P.
         Roozekrans.

Drawn up and signed in duplicate in Amsterdam on 5 July 1996.

1.       EUROMED EUROPE B.V.

         [signature]

(B.V. Wisteria)

2.       USUS NOTUS B.V. I.O.

         [signature]

(A. Doets)

(for him by power of attorney: N. Th. P. Roozekrans)

3.a.     MUTARESTES B.V.

         [signature]              [signature]

(N. Th. P. Roozekrans)            (A. Doets)

                                                  (for him by power of attorney)





                                       19
<PAGE>   10
                                        N. Th. P. Roozekrans

3.b.     PLURIPHARM INTERNATIONAL B.V.

         [signature]

(Mutarestes B.V.)

3.c.     FINANCIERINGSMAATSCHAPPIJ DE NIEUWE WERELD B.V.

         [signature]

(Mutarestes B.V.)

For articles 5.1, 5.2, 6, 8, 11.2, 11.3 and 11.4:

         [signature]

A. Doets

(For him by power of attorney: N. Th. Roozekrans)

EuroMed, Inc. guarantees the compliance with this Agreement by EuroMed B.V. and
by the Corporations.

         [signature]

(EuroMed, Inc.)





                                       20

<PAGE>   1

                                                                    EXHIBIT 10.2

Doc 1/
                            ref.: MS/MANAGEMENT.NTP

                              MANAGEMENT AGREEMENT

The undersigned:

1.       the closed corporation EUROMED EUROPE B.V., with registered office in
         Oosterhout, legally represented in this matter by its statutory
         director B.V. Wisteria, (hereafter called: "EuroMed B.V.");

2.       the closed corporation in formation N.T.P. ADVIES B.V. i.o., with
         registered office in Bergen (North Holland), legally represented in
         this matter by its organizer, Mr. N. Th. P. Roozekrans, (hereafter
         called: "NTP");

3.       a.      the closed corporation MUTARESTES B.V., with registered office
                 in Heerhugowaard, legally represented in this matter by its
                 statutory directors, Mr. A. Doets and Mr. N. Th. P.
                 Roozekrans, (hereafter called: "Mutarestes");
         b.      the closed corporation PLURIPHARM INTERNATIONAL B.V., with
                 registered office in Heerhugowaard, legally represented in
                 this matter by its statutory director, Mutarestes, (hereafter
                 called: "Pluripharm");
         c.      the closed corporation FINANCIERINGSMAATSCHAPPIJ DE NIEUWE
                 WERELD B.V., with registered office in Heerhugowaard, legally
                 represented in this matter by its statutory director,
                 Mutarestes, (hereafter called: "DNW");
         Parties numbered 3.a. through 3.c. hereafter also indicated as: "the
         Corporations"

TAKING INTO CONSIDERATION:

a.       EuroMed B.V., as 100% subsidiary of the corporation under the laws of
         the state of Nevada, United States, EUROMED INC.("EuroMed"), is the
         Netherlands holding company of EuroMed's operating companies;





                                       1
<PAGE>   2
b.       EuroMed B.V. holds 100% of the shares in the closed corporations
         Confedera B.V. ("Confedera") and Galenica B.V.  ("Galenica") and 100%
         of the shares in Mutarestes, which corporation in turn holds 100% of
         the shares in Pluripharm, which corporation in turn holds 100% of the
         shares in DNW;

c.       Confedera, Galenica, and Pluripharm are the operating companies within
         the EuroMed group which engage in the wholesaling of medicines;

d.       EuroMed B.V. wishes to ensure, by entering into management agreements,
         that executives are available who are responsible for the daily
         management of its operating companies during a specified time;

e.       In that connection, NTP is prepared and able to fulfill this need for
         the benefit of Mutarestes and its subsidiaries Pluripharm and DNW, by
         making a qualified executive available to Mutarestes on the following
         conditions;

HAVE AGREED AS FOLLOWS:

Article 1 Activities

1.1      For the duration of this agreement (the "Agreement"), NTP shall make a
         manager available to Mutarestes, i.e.  Mr. N. Th. P. Roozekrans
         (hereafter called: "Manager"). Mutarestes states that it agrees to
         this Manager and to let him perform the activities which are specified
         in the Agreement.

1.2      In the event that the Manager, for whatever reason, cannot perform his
         activities, NTP can propose a replacement manager to Mutarestes.
         Mutarestes shall inform NTP within one week in writing whether it
         agrees to the proposed replacement.

1.3      If it should be necessary for Mutarestes' conduct of business, EuroMed
         B.V. shall consult





                                       2
<PAGE>   3
         with NTP if it is of the opinion that the nature of the Manager's
         activities should be adjusted.

1.4      In view of the fact that the Manager is made available to Mutarestes
         by NTP, the parties recognize expressly that the Manager is not in the
         employ of Mutarestes, nor can be considered in any manner as an
         employee of Mutarestes.

1.5      For the performance of its activities, NTP shall be named a statutory
         director of Mutarestes, which corporation during the duration of this
         Agreement shall continue to function as a statutory director of
         Pluripharm and DNW.  With regard to its activities as statutory
         director, NTP shall be represented by the Manager, or by his
         replacement.

1.6      Mutarestes pledges to grant to the Manager that authority and
         cooperation which are required for the proper performance of his
         activities.

Article 2 Compensation

2.1      Mutarestes shall compensate NTP for its activities f 200,000 per year,
         excluding value added tax. Mutarestes shall pay the compensation in
         four equal installments per year. NTP shall send an invoice to
         Mutarestes once per quarter in which the activities of the Manager are
         also explained. Mutarestes shall pay the invoice within 30 days.

         It shall be further agreed among EuroMed B.V. and the Corporations, to
         which of the Corporations the payment obligations arising from the
         Agreement shall be charged.

2.2      NTP shall see to strict compliance with all obligations incumbent upon
         it with regard to value added tax and with regard to payroll tax and
         social insurance premiums relating to the Manager. NTP shall indemnify
         Mutarestes with regard to all possible claims by the tax authorities
         and/or the trade association against Mutarestes in the event that they
         should take the position that Mutarestes has a withholding or payment
         obligation with





                                       3
<PAGE>   4
         regard to the Manager for payroll tax and/or social insurance
         premiums, including increases, fines and interest.

2.3      If the Manager for whatever reason, during a period longer than two
         weeks, cannot perform any activities for Mutarestes and no appropriate
         replacement is provided, Mutarestes shall be released from its
         obligation for payment of the compensation, effective the third week,
         for the duration of the default, with the exception of compensation
         for reasonably incurred expenses which have occurred despite the
         absence of the Manager and which can no longer be reversed, provided
         these expenses fall within the ordered activities.

Article 3 Duration of the Agreement

3.1      The Agreement shall take effect retroactively as of 1 January 1996 for
         a period of 5 years and shall therefore terminate by operation of law
         on 31 December 2000, without a requirement for any further action of
         the parties.

3.2      Extension of the Agreement shall only be possible if the parties
         decide on it in writing.

3.3      EuroMed B.V. and NTP can each cancel the Agreement in the interim,
         with observance of a notice period of 6 months. Cancellation shall
         occur by means of a registered letter addressed to the management of
         the other party.

3.4      The Agreement can be cancelled with immediate effect if:

         a.      NTP or Mutarestes is declared bankrupt or if suspension of
                 payment is granted to NTP or Mutarestes;

         b.      the Manager dies, is declared bankrupt or the Manager is
                 granted suspension of payment or, in the event of illness or
                 otherwise during a period of three





                                       4
<PAGE>   5
                 consecutive months, the Manager has not been able, for more
                 than thirty-five days, to fulfill the obligations of article 1
                 and Mutarestes has not accepted NTP's offer pursuant to
                 article 1.2.

3.5      NTP and Mutarestes shall have the authority to dissolve the Agreement
         if a party to the Agreement does not comply with, or comply with on
         time, or properly comply with, an obligation from the Agreement.

Article 4 Liability

4.1      NTP and the Manager shall not be liable to Mutarestes, nor to third
         parties, for damages which arise from the action or failure to act of
         the Manager, performed within the formal sphere of his authority,
         without prejudice to liability which arises from the intentional or
         gross fault of NTP and/or the Manager.

4.2      Mutarestes releases NTP and the Manager in the event of liability of
         NTP and/or the Manager to third parties for actions or failure to act
         of the Manager, performed within the formal sphere of his authority,
         unless the liability arises from the intentional or gross fault of NTP
         and/or the Manager.

Article 5 Competition clause

5.1      Neither NTP nor its direct or indirect shareholder shall, during the
         period from the effective date of the Agreement until five years after
         the termination of the Agreement, conduct any activity, direct or
         indirect, by means of a legal entity or otherwise, alone or in
         cooperation with others, within the Benelux, which in any manner could
         be in competition with the activities of Mutarestes, other than
         activities with regard to having pharmacies. Neither NTP nor its
         direct or indirect shareholder shall make any investments in competing
         companies. Interests existing at the time of entering into this
         Agreement can be maintained.





                                       5
<PAGE>   6
5.2      Upon violation of the competition clause in article 5.1, NTP shall owe
         a fine of f 1,000,000 per violation, with an increase of f 10,000 per
         day that the violation continues after notice of default. The Manager
         shall be jointly and severally liable with NTP for this fine.

Article 6 Confidentiality requirement

6.1      NTP shall observe strict confidentiality during the period of the
         Agreement and thereafter regarding all that which it shall learn
         regarding the business and interests of Mutarestes and the companies
         connected with Mutarestes, including particularly (but not limited to)
         knowledge regarding the pricing used by Pluripharm and discounts and
         relationships with customers.

6.2      NTP shall be required to impose this confidentiality requirement upon
         the Manager and his replacements unabridged.

6.3      Regardless of the manner in which this Agreement is terminated, NTP
         shall return all property of the Corporations to the Corporations,
         including (but not limited to) all data carriers, copies, books and
         documents which contain data from the Corporations.

Article 7 Obligation of the Manager

7.1      NTP shall guarantee that the provisions of articles 5, 6 and 8 shall
         be correspondingly applicable to the Manager. As a sign of his
         agreement to bound by these articles, the Manager shall co-sign the
         Agreement.

Article 8 Intellectual property

8.1      The intellectual property rights with regard to new products developed
         during the period of the Agreement by or in cooperation with NTP shall
         rest with Pluripharm and, insofar





                                       6
<PAGE>   7
         as necessary, NTP shall transfer these unconditionally to Pluripharm
         and they shall be unconditionally accepted by Pluripharm.

8.2      NTP shall not in any manner, directly or indirectly, by means of legal
         entities or otherwise, make use of the industrial property rights
         which have been in the past or are now used by Pluripharm for the
         conduct of Pluripharm's business.

Article 9 Invalid provisions

9.1      If one or more articles of the Agreement should be invalid or in
         another manner not binding, the validity of the remaining articles of
         the Agreement shall not thereby be affected. The parties shall then
         adjust the Agreement in mutual consultation, such that the non-binding
         articles shall be replaced by other provisions which differ as little
         as possible from the relevant non-binding articles.

Article 10 Applicable law and choice of forum

Netherlands law shall be applicable to the Agreement. Any dispute which shall
arise from the Agreement shall be subject exclusively to judgment by the
authorized court in the District of Arnhem.

Article 11       Supplementary clauses

11.1     The Corporations accept joint and several liability for the payment
         obligations of Mutarestes under the Agreement.

11.2     In the performance of the management activities, the reasonable
         interests of the other operating companies of EuroMed B.V. will
         continually be observed, such that the activities to be performed in
         respect of the Agreement shall not be damaging to the other operating
         companies.





                                       7
<PAGE>   8
11.3     a.      The Manager shall agree to consult regularly, but at least
                 once a month, with the management of Galenica and Confedera
                 regarding the state of affairs within the Corporations and the
                 policy to be carried out regarding the Corporations.

11.3     b.      NTP shall annually, at the latest on 1 December of a fiscal
                 year, develop a business plan in consultation with and for the
                 approval of the management of Galenica and Confedera, in which
                 the commercial objectives for the Corporations for the
                 following fiscal year shall be established (the "Business
                 Plan").

11.3     c.      During a fiscal year, NTP shall carry out the management and
                 policy with regard to the Corporations as much as possible in
                 accordance with the Business Plan.

11.3     d.      If and insofar as NTP notices that the actual developments of
                 the Corporations are going to deviate from the Business Plan,
                 NTP shall notify the management of Galenica and Confedera of
                 this as quickly as possible. Then, in mutual consultation,
                 measures to be taken shall be decided on and, if necessary,
                 the Business Plan for the relevant year shall be modified.

11.4     Manager accepts that, with regard to the actions named below
         concerning the Corporations, the express approval of the management of
         Galenica and Confedera shall be required:

         a.      any substantial and/or fundamental change in the conduct of
                 business of the relevant Corporation, such as change in the
                 distribution and/or production strategy;
         b.      contracting with or dismissal of employees, or the adjustment
                 or changing of conditions of employment, other than providing
                 for the replacement of existing employees;
         c.      changing of bank relationships or of the conditions thereof
                 which have already been entered into by the relevant
                 corporation;





                                       8
<PAGE>   9
         d.      entering into transactions which exceed the amount of f
                 100,000; 
         e.      settling any claim which exceeds the amount of f 30,000; 

         f.      acquiring or disposing of investments in other
                 corporations.

11.5     EuroMed B.V. agrees not to make any change in the statutory management
         of the Corporations during the period of this Agreement.

11.6     EuroMed B.V. agrees, in its capacity of sole shareholder of
         Mutarestes, that this Agreement shall be signed on behalf of
         Mutarestes by its statutory directors A. Doets and N. Th. P.
         Roozekrans.

Drawn up and signed in duplicate in Amsterdam on 5 July 1996.

1.       EUROMED EUROPE B.V.

         [signature]

(B.V. Wisteria)

2.       N.T.P. ADVIES B.V. I.O.

         [signature]

(N. Th. P. Roozekrans)

3.a.     MUTARESTES B.V.

         [signature]              [signature]

(N. Th. P. Roozekrans)            (A. Doets)
                                                  (for him by power of attorney)

                                                            N. Th. P. Roozekrans





                                       9
<PAGE>   10
3.b.    PLURIPHARM INTERNATIONAL B.V.

         [signature]

(Mutarestes B.V.)

3.c.     FINANCIERINGSMAATSCHAPPIJ DE NIEUWE WERELD B.V.

         [signature]

(Mutarestes B.V.)

For articles 5.1, 5.2, 6, 8, 11.2, 11.3 and 11.4:

         [signature]

(N. Th. Roozekrans)

EuroMed, Inc. guarantees the compliance with this Agreement by EuroMed B.V. and
by the Corporations.

         [signature]

(EuroMed, Inc.)





                                       10

<PAGE>   1
                                                                    EXHIBIT 10.3


Doc 3/

                            ref.: MS/MANAGEMENT.WIS

                              MANAGEMENT AGREEMENT

The undersigned:

1.       the closed corporation EUROMED EUROPE B.V., with registered office in
         Oosterhout, legally represented in this matter by its statutory
         director B.V. Wisteria, (hereafter called: "EuroMed B.V.");

2.       the closed corporation B.V. WISTERIA, with registered office in
         Arnhem, legally represented in this matter by its statutory director,
         Pantapharma B.V. (hereafter called: "Wisteria");

3.       a.      the closed corporation GALENICA B.V., with registered office
                 in Bilthoven, legally represented in this matter by its
                 statutory director, B.V. Wisteria, (hereafter called:
                 "Galenica");

         b.      the closed corporation CONFEDERA B.V., with registered office
                 in Oosterhout, legally represented in this matter by its
                 statutory director, B.V. Wisteria, (hereafter called:
                 "Confedera");

         Parties numbered 3.a. and 3.b. hereafter also indicated as: "the
         Corporations"

TAKING INTO CONSIDERATION:

a.       EuroMed B.V., as 100% subsidiary of the corporation under the laws of
         the state of Nevada, United States, EUROMED INC.("EuroMed"), is the
         Netherlands holding company of EuroMed's operating companies;





                                       21
<PAGE>   2
b.       EuroMed B.V. holds 100% of the shares in Confedera and Galenica and
         100% of the shares in the closed corporation Mutarestes B.V.
         ("Mutarestes"), which corporation in turn holds 100% of the shares in
         Pluripharm International B.V. ("Pluripharm"), which corporation in
         turn holds 100% of the shares in Financieringsmaatschappij De Nieuwe
         Wereld ("DNW");

c.       Confedera, Galenica, and Pluripharm are the operating companies within
         the EuroMed group which engage in the wholesaling of medicines;

d.       EuroMed B.V. wishes to ensure, by entering into management agreements,
         that executives are available who are responsible for the daily
         management of its operating companies during a specified time;

e.       In that connection, Wisteria is prepared and able to fulfill this need
         for the benefit of Confedera and Galenica, by making a qualified
         executive available to Confedera and Galencia on the following
         conditions;

HAVE AGREED AS FOLLOWS:

Article 1 Activities

1.1      For the duration of this agreement (the "Agreement"), Wisteria shall
         make a manager available to the Corporations, i.e. Mr. A. F. Hinnen
         (hereafter called: "Manager"). The Corporations state that they agree
         to this Manager and to let him perform the activities which are
         specified in the Agreement.

1.2      In the event that the Manager, for whatever reason, cannot perform his
         activities, Wisteria can propose a replacement manager to the
         Corporations. The Corporations shall inform Wisteria within one week
         in writing whether they agree to the proposed replacement.





                                       22
<PAGE>   3
1.3      If it should be necessary for the Corporations' conduct of business,
         EuroMed B.V. shall consult with Wisteria if it is of the opinion that
         the nature of the Manager's activities should be adjusted.

1.4      In view of the fact that the Manager is made available to the
         Corporations by Wisteria, the parties recognize expressly that the
         Manager is not in the employ of the Corporations, nor can be
         considered in any manner as an employee of the Corporations.

1.5      For the performance of its activities, Wisteria shall be named a
         statutory director of the Corporations and during the duration of this
         Agreement shall continue to function as a statutory director of the
         Corporations.  With regard to its activities as statutory director,
         Wisteria shall be represented by the Manager, or by his replacement.

1.6      The Corporations pledge to grant to the Manager that authority and
         cooperation which are required for the proper performance of his
         activities.

Article 2 Compensation

2.1      The Corporations shall compensate Wisteria for its activities together
         in total f 200,000 per year, excluding value added tax. The
         Corporations shall pay the compensation in four equal installments per
         year. Wisteria shall send an invoice to the Corporations once per
         quarter in which the activities of the Manager are also explained. The
         Corporations shall pay the invoice within 30 days.

         It shall be further agreed among EuroMed B.V. and the Corporations, to
         which of the Corporations the payment obligations arising from the
         Agreement shall be charged.

2.2      Wisteria shall see to strict compliance with all obligations incumbent
         upon it with regard to value added tax and with regard to payroll tax
         and social insurance premiums relating to the Manager. Wisteria shall
         indemnify the Corporations with regard to all possible





                                       23
<PAGE>   4
         claims by the tax authorities and/or the trade association against the
         Corporations in the event that they should take the position that the
         Corporations have a withholding or payment obligation with regard to
         the Manager for payroll tax and/or social insurance premiums,
         including increases, fines and interest.

2.3      If the Manager for whatever reason, during a period longer than two
         weeks, cannot perform any activities for the Corporations and no
         appropriate replacement is provided, the Corporations shall be
         released from their obligation for payment of the compensation,
         effective the third week, for the duration of the default, with the
         exception of compensation for reasonably incurred expenses which have
         occurred despite the absence of the Manager and which can no longer be
         reversed, provided these expenses fall within the ordered activities.

Article 3 Duration of the Agreement

3.1      The Agreement shall take effect retroactively as of 1 January 1996 for
         a period of 5 years and shall therefore terminate by operation of law
         on 31 December 2000, without a requirement for any further action of
         the parties.

3.2      Extension of the Agreement shall only be possible if the parties
         decide on it in writing.

3.3      EuroMed B.V. and Wisteria can each cancel the Agreement in the
         interim, with observance of a notice period of 6 months. Cancellation
         shall occur by means of a registered letter addressed to the
         management of the other party.

3.4      The Agreement can be cancelled with immediate effect if:

         a.      Wisteria or one of the Corporations is declared bankrupt or if
                 suspension of payment is granted to Wisteria or one of the
                 Corporations;





                                       24
<PAGE>   5
         b.      the Manager dies, is declared bankrupt or the Manager is
                 granted suspension of payment or, in the event of illness or
                 otherwise during a period of three consecutive months, the
                 Manager is not able, for more than thirty-five days, to
                 fulfill the obligations of article 1 and the Corporations have
                 not accepted Wisteria's offer pursuant to article 1.2.

3.5      Wisteria and the Corporations shall have the authority to dissolve the
         Agreement if a party to the Agreement does not comply with, or comply
         with on time, or properly comply with, an obligation from the
         Agreement.

Article 4 Liability

4.1      Wisteria and the Manager shall not be liable to the Corporations, as
         well as to third parties, for damage which arises from the action or
         failure to act of the Manager, performed within the formal sphere of
         his authority, without prejudice to liability which arises from the
         intentional or gross fault of Wisteria and/or the Manager.

4.2      The Corporations release Wisteria and the Manager in the event of
         liability of Wisteria and/or the Manager to third parties for actions
         or failure to act of the Manager, performed within the formal sphere
         of his authority, unless the liability arises from the intentional or
         gross fault of Wisteria and/or the Manager.

Article 5 Competition clause

5.1      Neither Wisteria nor its direct or indirect shareholder shall, during
         the period from the effective date of the Agreement until five years
         after the termination of the Agreement, conduct any activity, direct
         or indirect, by means of a legal entity or otherwise, alone or in
         cooperation with others, within the Benelux, which in any manner could
         be in competition with the activities of the Corporations, other than
         activities with regard to having pharmacies. Neither Wisteria nor its
         direct or indirect shareholder shall make any





                                       25
<PAGE>   6
         investments in competing companies. Interests existing at the time of
         entering into this Agreement can be maintained.

5.2      Upon violation of the competition clause in article 5.1, Wisteria
         shall owe a fine of f 1,000,000 per violation, with an increase of f
         10,000 per day that the violation continues after notice of default.
         The Manager shall be jointly and severally liable with Wisteria for
         this fine.

Article 6 Confidentiality requirement

6.1      Wisteria shall observe strict confidentiality during the period of the
         Agreement and thereafter regarding all that which it shall learn
         regarding the business and interests of the Corporations and the
         companies connected with the Corporations, including particularly (but
         not limited to) knowledge regarding the pricing used by the
         Corporations and discounts and relationships with customers.

6.2      Wisteria shall be required to impose this confidentiality requirement
         upon the Manager and his replacements unabridged.

6.3      Regardless of the manner in which this Agreement is terminated,
         Wisteria shall return all property of the Corporations to the
         Corporations, including (but not limited to) all data carriers,
         copies, books and documents which contain data from the Corporations.

Article 7 Obligation of the Manager

7.1      Wisteria shall guarantee that the provisions of articles 5, 6 and 8
         shall be correspondingly applicable to the Manager. As a sign of his
         agreement to be bound by these articles, the Manager shall co-sign the
         Agreement.

Article 8 Intellectual property





                                       26
<PAGE>   7
8.1      The intellectual property rights with regard to new products developed
         during the period of the Agreement by or in cooperation with the
         Corporations shall rest with the Corporations and, insofar as
         necessary, Wisteria shall transfer these unconditionally to the
         Corporations and they shall be unconditionally accepted by the
         Corporations.

8.2      Wisteria shall not in any manner, directly or indirectly, by means of
         legal entities or otherwise, make use of the industrial property
         rights which have been in the past or are now used by the Corporations
         for the conduct of the Corporations' business.

Article 9 Invalid provisions

9.1      If one or more articles of the Agreement should be invalid or in
         another manner not binding, the validity of the remaining articles of
         the Agreement shall not thereby be affected. The parties shall then
         adjust the Agreement in mutual consultation in the sense that the
         non-binding articles shall be replaced by other provisions which
         differ as little as possible from the relevant non-binding articles.

Article 10 Applicable law and choice of forum

Netherlands law shall be applicable to the Agreement. Any dispute which shall
arise from the Agreement shall be subject exclusively to judgment by the
authorized court in the District of Arnhem.

Article 11       Supplementary clauses

11.1     The Corporations accept joint and several liability for the payment
         obligations of the Corporations under the Agreement.

11.2     In the performance of the management activities, the reasonable
         interests of the other operating companies of EuroMed B.V. will
         continually be observed, such that the





                                       27
<PAGE>   8
         activities to be performed in respect of the Agreement shall not be
         damaging to the other operating companies.

11.3     a.      The Manager shall agree to consult regularly, but at least
                 once a month, with the management of Mutarestes, Pluripharm
                 and De Nieuwe Wereld regarding the state of affairs within the
                 Corporations and the policy to be carried out regarding the
                 Corporations.

11.3     b.      Wisteria shall annually, at the latest on 1 December of a
                 fiscal year, develop a business plan in consultation with and
                 for the approval of the management of Mutarestes, Pluripharm
                 and De Nieuwe Wereld, in which the commercial objectives for
                 the Corporations for the following fiscal year shall be
                 established (the "Business Plan").

11.3     c.      During a fiscal year, Wisteria shall carry out the management
                 and policy with regard to the Corporations as much as possible
                 in accordance with the Business Plan.

11.3     d.      If and insofar as Wisteria notices that the actual
                 developments of the Corporations are going to deviate from the
                 Business Plan, Wisteria shall notify the management of
                 Mutarestes, Pluripharm and De Nieuwe Wereld of this as quickly
                 as possible. Then, in mutual consultation, measures to be
                 taken shall be decided on and, if necessary, the Business Plan
                 for the relevant year shall be modified.

11.4     Manager accepts that, with regard to the actions named below
         concerning the Corporations, the express approval of the management of
         Mutarestes, Pluripharm and De Nieuwe Wereld shall be required: 

         a.      any substantial and/or fundamental change in the conduct of 
                 business of the relevant Corporation, such as change in the 
                 distribution and/or production strategy;





                                       28
<PAGE>   9
         b.      contracting with or dismissal of employees, or the adjustment
                 or changing of conditions of employment, other than providing
                 for the replacement of existing employees;

         c.      changing of bank relationships or of the conditions thereof
                 which have already been entered into by the relevant
                 corporation;

         d.      entering into transactions which exceed the amount of f
                 100,000;

         e.      settling any claim which exceeds the amount of f 30,000;

         f.      acquiring or disposing of investments in other corporations.

         g.      ending this Management Agreement in the manner stated in
                 article 3.3.

11.5     EuroMed B.V. agrees not to make any change in the statutory management
         of the Corporations during the period of this Agreement.

11.6     EuroMed B.V. agrees, in its capacity of sole shareholder of the
         Corporations, that this Agreement shall be signed on behalf of the
         Corporations by their statutory director Wisteria.

Drawn up and signed in duplicate in Amsterdam on 5 July 1996.

1.       EUROMED EUROPE B.V.

         [signature]

(B.V. Wisteria)

2.       B.V. WISTERIA

         [signature]

(A. F. Hinnen)

3.a.     GALENICA B.V.





                                       29
<PAGE>   10
         [signature]

(B.V. Wisteria)

3.b.     CONFEDERA B.V.

         [signature]

(B.V. Wisteria)

For articles 5.1, 5.2, 6, 8, 11.2, 11.3 and 11.4:

         [signature]

A. F. Hinnen

EuroMed, Inc. guarantees the compliance with this Agreement by EuroMed B.V. and
by the Corporations.

         [signature]

(EuroMed, Inc.)





                                       30


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