MILESTONE SCIENTIFIC INC/NJ
SC 13D, 1997-09-22
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                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549


                                SCHEDULE 13D 

                    Under the Securities Exchange Act of 1934


                           Milestone Scientific, Inc.
- --------------------------------------------------------------------------------
                                (Name of Issuer)


                     Common Stock, par value $.001 per share
                         (Title of Class of Securities)

                                    59935P100
                                 (CUSIP Number)
- --------------------------------------------------------------------------------

                    Paramount Capital Asset Management, Inc.
                         c/o Lindsay A. Rosenwald, M.D.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4300

                                 with a copy to:

                              David R. Walner, Esq.
                    Paramount Capital Asset Management, Inc.
                               787 Seventh Avenue
                               New York, NY 10019
                                 (212) 554-4372
- --------------------------------------------------------------------------------
       (Name, Address and Telephone Number of Person Authorized to Receive
                           Notices and Communications)


                               September 11, 1997
- --------------------------------------------------------------------------------
                 (Date of Event which Requires Filing of this Statement)

If the filing person has previously  filed a statement on Schedule 13G to report
the  acquisition  which is the subject of this  Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following:     [_]

Note: Six copies of this statement, including all exhibits, should be filed with
the  Commission.  See Rule 13d- 1(a) for other  parties to whom copies are to be
sent.

Check the following box if a fee is being paid with this Statement:     [_]


                               Page 1 of 10 Pages

<PAGE>


- --------------------------                       -------------------------------
CUSIP No. 59935P100              13D                     Page 2 of 10 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Paramount Capital Asset Management, Inc.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 415,832
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          415,832
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           415,832
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           5.5% /1/ 
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           CO
- -------------------------------------------------------------------------------

- --------

/1/ As of September 11, 1997, the date of the first event  requiring this filing
Paramount Capital Asset Management,  Inc.  beneficially  owned 521,465 shares of
common  stock of the  Issuer  or 6.9%.  As a result  of  certain  sales  further
described  in Item  5(c),  as of the date of  hereof,  Paramount  Capital  Asset
Management,  Inc. beneficially owned 416,332 shares of common stock resulting in
beneficial ownership of 5.5% as shown in box 13 above.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 59935P100              13D                     Page 3 of 10 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Aries Domestic Fund, L.P.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Delaware

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 141,412
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          141,412
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           141,412
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           1.9% /2/
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           PN
- -------------------------------------------------------------------------------

- -------- 

/2/ As of September 11, 1997,  Aries  Domestic  Fund,  L.P.  beneficially  owned
178,389  shares of common  stock of the  Issuer or 2.4%.  As a result of certain
sales further  described in Item 5(c), as of the date of hereof,  Aries Domestic
Fund,  L.P.  beneficially  owned  141,412  shares of common  stock  resulting in
beneficial ownership of 1.9% as shown in box 13 above.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 59935P100              13D                     Page 4 of 10 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           The Aries Fund, A Cayman Island Trust
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           Cayman Islands

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 274,420
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          274,420
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           274,420
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           3.6% /3/
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           OO (see Item 2)
- -------------------------------------------------------------------------------

- --------

/3/ As of September 11, 1997, the Aries Fund, a Cayman Island Trust beneficially
owned  343,076  shares of  common  stock of the  Issuer  or  3.6%.As a result of
certain  sales further  described in Item 5(c), as of the date of hereof,  Aries
Domestic Fund, L.P.  beneficially owned 343,076 shares of common stock resulting
in beneficial ownership of 4.6% as shown in box 13 above.


<PAGE>

- --------------------------                       -------------------------------
CUSIP No. 59935P100              13D                     Page 5 of 10 Pages
- --------------------------                       -------------------------------

- -------------------------------------------------------------------------------
    1      NAMES OF REPORTING PERSONS
           S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

           Lindsay A Rosenwald, M.D.
- -------------------------------------------------------------------------------
    2      CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP    (a)   [_]
                                                               (b)   [_]


- -------------------------------------------------------------------------------
    3      SEC USE ONLY



- -------------------------------------------------------------------------------
    4      SOURCE OF FUNDS*

           OO (see Item 3)
- -------------------------------------------------------------------------------
    5      CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED 
           PURSUANT TO ITEM 2(d) or 2(e)
                                                                     [_]
- -------------------------------------------------------------------------------
    6      CITIZENSHIP OR PLACE OF ORGANIZATION

           United States

- -------------------------------------------------------------------------------
                                   7      SOLE VOTING POWER

                                          None
                 NUMBER OF         --------------------------------------------
                  SHARES           8      SHARED VOTING POWER    
               BENEFICIALLY
                 OWNED BY                 415,832
                   EACH            --------------------------------------------
                REPORTING          9      SOLE DISPOSITIVE POWER 
                  PERSON
                   WITH                   None 
                                   --------------------------------------------
                                   10     SHARED DISPOSITIVE POWER

                                          415,832
- -------------------------------------------------------------------------------
    11     AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

           415,832
- -------------------------------------------------------------------------------
    12     CHECK BOX IF THE AGGREGATE AMOUNT IN ROW 11 EXCLUDES CERTAIN SHARES*

                                                                     [_]
- -------------------------------------------------------------------------------
    13     PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

           5.5% /4/
- -------------------------------------------------------------------------------
    14     TYPE OF REPORTING PERSON*

           IN
- -------------------------------------------------------------------------------

- --------

/4/ As of September 11, 1997,  Lindsay A.  Rosenwald,  M.D.  beneficially  owned
415,832  shares of common  stock of the  Issuer or 5.5%.  As a result of certain
sales further  described in Item 5(c), as of the date of hereof,  Aries Domestic
Fund,  L.P.  beneficially  owned  521,465  shares of common  stock  resulting in
beneficial ownership of 5.5% as shown in box 13 above.


<PAGE>

Item 1.  Security and Issuer.

     (a)  Common Stock, $.001 par value ("Shares")

           Milestone Scientific, Inc.
           220 South Orange Avenue
           Livingston, N.J. 07039

Item 2.  Identity and Background.

         Names of Persons Filing:

     (a)  This  statement  is  filed  on  behalf  of  Paramount   Capital  Asset
          Management,  Inc.  ("Paramount  Capital "), Aries Domestic Fund,  L.P.
          ("Aries  Domestic"),  The Aries Fund, A Cayman  Island  Trust  ("Aries
          Trust") and Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald")(collectively,
          "Reporting Parties").  See attached Exhibit A which is a copy of their
          agreement in writing to file this statement on behalf of each of them.

     (b)  The business  address of  Paramount  Capital,  Aries  Domestic and Dr.
          Rosenwald  is 787  Seventh  Avenue,  New York,  New York,  10019.  The
          business address for Aries Trust is c/o MeesPierson  (Cayman) Limited,
          P.O.  Box 2003,  British  American  Centre,  Phase 3, Dr. Roy's Drive,
          George Town, Grand Cayman.

     (c)  Dr.  Rosenwald is an investment  banker,  venture  capitalist and fund
          manager  and  is the  sole  shareholder  of  Paramount  Capital,/5/  a
          Subchapter S corporation  incorporated in Delaware.  Paramount Capital
          is the General  Partner of Aries  Domestic,/6/  a limited  partnership
          incorporated  in  Delaware  and is the  Investment  Manager  to  Aries
          Trust,/7/ a Cayman Islands Trust.

     (d)  Dr. Rosenwald,  Paramount Capital,  Aries Domestic and Aries Trust and
          their respective  officers,  directors,  general partners,  investment
          managers,  or  trustees  have not,  during the five years prior to the
          date  hereof,  been con  victed in a  criminal  proceeding  (excluding
          traffic violations or similar misdemeanors).

     (e)  Dr. Rosenwald,  Paramount Capital,  Aries Domestic and Aries Trust and
          their respective  officers,  directors,  general partners,  investment
          managers,  or trustees  have not been,  during the five years prior to
          the date  hereof,  parties  to a civil  proceeding  of a  judicial  or
          administrative  body of competent juris diction,  as a result of which
          such  person was or is subject  to a  judgment,  

- -------- 

/5/  Please  see  attached  Exhibit B  indicating  the  executive  officers  and
directors of Paramount Capital and providing information called for by Items 2-6
of this  statement  as to said  officers  and  directors.  Exhibit  B is  herein
incorporated  by  reference.

/6/  Please see  attached  Exhibit C  indicating  the  general  partner of Aries
Domestic  and  the  general  partner's  executive  officers  and  directors  and
providing  information  called  for by Items  2-6 of this  statement  as to said
general partners,  officers and directors.  Exhibit C is herein  incorporated by
reference.

/7/ Please see attached Exhibit D indicating the investment manager of the Aries
Trust  and the  investment  manager's  executive  officers  and  direc  tors and
providing  information  called  for by Items  2-6 of this  statement  as to said
investment manager and officers and directors.  Exhibit D is herein incorporated
by reference.


                               Page 6 of 10 Pages

<PAGE>

          decree or final order enjoining  future  violations of, or prohibiting
          or mandating  activities  subject to, Federal or State securities laws
          or finding any violation with respect to such laws.

     (f)  Dr. Rosenwald is a citizen of the United States.

Item 3.  Source and Amount of Funds or Other Consideration.

          On  March  13,  1997,  in a  private  placement  (the  "March  Private
          Placement")  of the  Issuer's  securities,  Aries  Domestic  used  its
          general funds to acquire 37,077 Units,  each "Unit"  consisting of (a)
          one (1) share of common stock of the Issuer (the  "Common  Stock") and
          (b) one (1) warrant to purchase  one (1) share of Common  Stock of the
          Issuer at an exercise  price equal to $4.72 for an aggregate  purchase
          price of  $350,000,  and the Aries  Trust  used its  general  funds to
          acquire  68,856  Units  for  an  aggregate  purchase  price  equal  to
          $650,000.   On  September  11,  1997,  in  a  private  placement  (the
          "September Private Placement") of the Issuer's  securities,  the Aries
          Domestic used its general funds to acquire  70,606 units,  each "Unit"
          consisting  of (a) one (1) share of Common Stock of the Issuer and (b)
          one (1)  warrant  to  purchase  one (1) share of  Common  Stock of the
          Issuer at an exercise  price equal to $9.00 for an aggregate  purchase
          price of  $423,636,  and the Aries  Trust  used its  general  funds to
          acquire 137,060 Units for an aggregate purchase price of $822,360.

Item 4.  Purpose of Transaction.

          The  Reporting  Parties  acquired  securities  of  the  Issuer  as  an
          investment in the Issuer.

          In the past sixty (60) days,  the Reporting  Parties have sold certain
          shares  of Common  Stock of the  Issuer  as  reported  in Item 5, and,
          although the  Reporting  Parties have not  formulated  any  definitive
          plans to do so,  they may from time to time  acquire,  dispose  of, or
          engage in other  transactions  with respect to the Common Stock and/or
          other  securities of the Issuer if and when they deem it  appropriate.
          The Reporting Parties may formulate other purposes, plans or proposals
          relating to any of such  securities of the Issuer to the extent deemed
          advisable in light of market conditions, investment policies and other
          factors.

          Except as  indicated  in this  Schedule  13D,  the  Reporting  Parties
          currently have no plans or proposals that relate to or would result in
          any of the matters  described in subparagraphs (a) through (j) of Item
          4 of Schedule 13D.

Item 5.  Interest in Securities of the Issuer.

          (a)  As of September 11, 1997,  Dr.  Rosenwald and Paramount  Capital,
               through  acquisition  of the shares by the Aries  Trust and Aries
               Domestic,  beneficially  owned  521,465  shares  or  6.9%  of the
               Issuer's  securities  and  Aries  Domestic  and the  Aries  Trust
               beneficially owned as follows:

                                                  Amount Owned
               Aries Domestic                     178,289 Shares
               Aries Trust                        343,076 Shares

               As a result of the sales  described in Item 5(c), as of September
               18, 1997, Dr. Rosenwald and Paramount Capital  beneficially owned
               416,332  shares  or 5.5% of the  Issuer's  securities  and  Aries
               Domestic and the Aries Trust beneficially owned as follows:


                               Page 7 of 10 Pages

<PAGE>

                                                   Amount Owned
                Aries Domestic                     141,412 Shares
                Aries Trust                        274,920 Shares

          (b)  Dr. Rosenwald and Paramount Capital share the power to vote or to
               direct the vote, to dispose or to direct the disposition of those
               shares owned by each of Aries Domestic and Aries Trust.

          (c)  The  following  sales  were  made by Aries  Domestic  in the open
               market in the past 60 days:


               Date                      No. of Shares              Sales Price
               ----                      -------------              -----------
                9/05/97                       17,000                     8.798
                9/08/97                       19,977                     9.175
                9/16/97                       15,000                    13.5833
                9/17/97                       10,000                    12.8125
                9/18/97                       11,962                    12.97

               The  following  sales were made by Aries Trust in the open market
               in the past 60 days:

                Date                      No. of Shares              Sales Price
                ----                      -------------              -----------
                 9/05/97                      35,000                     8.798
                 9/08/97                      33,756                     9.175
                 9/16/97                      30,000                    13.5833
                 9/17/97                      15,000                    12.8125
                 9/18/97                      23,756                    12.97
                                                                  
                Other than as set forth herein the Reporting  Parties
                have not  engaged in any  transactions  in the Common
                Stock of the Issuer during the past 60 days.

                Other than as set forth herein the Reporting  Parties
                have not  engaged in any  transactions  in the Common
                Stock of the Issuer during the past 60 days.

          (d) & (e) Not applicable.

Item 6.  Contracts, Arrangements, Understandings or Relationships
         with respect to Securities of the Issuer

          Paramount Capital is the Investment Manager of the Aries Trust and the
          General  Partner  of Aries  Domestic  and in such  capacities  has the
          authority  to make  certain  investment  decisions  on  behalf of such
          entities,  including  decisions  relating  to  the  securities  of the
          Issuer. In connection with its investment management duties, Paramount
          Capital receives certain  management fees and performance  allocations
          from  the  Aries  Trust  and  Aries  Domestic.  Dr.  Rosenwald  is the
          President and sole shareholder of Paramount Capital.

          In  connection  with the March  Private  Placement  and the  September
          Private Placement,  Aries Domestic and the Aries Trust,  respectively,
          entered into certain  agreements with the Company,  including  without
          limitation, a subscription agreement,  warrant and registration rights
          agreement (See Exhibits B, C and D to Schedule 13D filed by New Valley
          Corp.  on  September  15,  1997  for form of  subscription  agreement,
          warrant and registration rights agreement).


                               Page 8 of 10 Pages

<PAGE>

                  Except  as  indicated  in this 13D and  exhibits,  there is no
                  contract,  arrangement,  understanding or relationship between
                  the Reporting  Parties and any other  person,  with respect to
                  any securities of the Issuer.

Item 7.  Material to be Filed as Exhibits:

Exhibit A  -   Copy  of  an  Agreement  between  Dr.  Rosenwald,  Paramount
               Capital, Aries Domestic and Aries Trust to file this Statement on
               Schedule 13D on behalf of each of them.

Exhibit B  -   List of  executive  officers  and  directors  of Paramount
               Capital  and  information  called  for by  Items  2-6 of  this
               statement relating to said officers and directors.

Exhibit C  -   List of executive officers and directors of Aries Domestic
               and  information  called  for by Items  2-6 of this  statement
               relating to said officers and direc tors.

Exhibit D  -   List of executive  officers  and  directors of Aries Trust
               and  information  called  for by Items  2-6 of this  statement
               relating to said officers and directors.


                               Page 9 of 10 Pages

<PAGE>

                                   SIGNATURES

         After  reasonable  inquiry and to the best  knowledge and belief of the
undersigned,  the  undersigned  certify that the  information  set forth in this
statement is true, complete and correct.

                                PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   September 19, 1997
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President

                                 ARIES DOMESTIC FUND, L.P.
                                 By: Paramount Capital Asset Management, Inc.
                                 General Partner

Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


                                 THE ARIES TRUST
                                 By: Paramount Capital Asset Management, Inc.
                                      General Partner

Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.



                               Page 10 of 10 Pages

<PAGE>

                                    EXHIBIT A

         The  undersigned  hereby  agrees  to  jointly  prepare  and  file  with
regulatory  authorities  a  Schedule  13D  and  any  future  amendments  thereto
reporting  each  of the  undersigned's  ownership  of  securities  of  Milestone
Scientific,  Inc.  and hereby  affirm that such  Schedule  13D is being filed on
behalf of each of the undersigned.

                                PARAMOUNT CAPITAL ASSET MANAGEMENT, INC.

Dated:   September 19, 1997
         New York, NY            By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President

                                 ARIES DOMESTIC FUND, L.P.
                                 By: Paramount Capital Asset Management, Inc.
                                      General Partner

Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


                                 THE ARIES TRUST
                                 By: Paramount Capital Asset Management, Inc.
                                      General Partner

Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.
                                     President


Dated:   September 19, 1997
         New York, NY             By: /s/ Lindsay A. Rosenwald
                                     ---------------------------------------
                                     Lindsay A. Rosenwald, M.D.


<PAGE>

                                    EXHIBIT B

         The name and principal occupation or employment, which in each instance
is with Paramount Capital Asset Management,  Inc. ("Paramount  Capital") located
at 787 Seventh Avenue,  New York, New York, 10019, of each executive officer and
director of Paramount Capital is as follows:

                                                 PRINCIPAL OCCUPATION
         NAME                                        OR EMPLOYMENT
         ----                                        -------------

Lindsay A. Rosenwald, M.D.           Chairman of the Board, President of
                                     Paramount Capital Asset Management, Inc.,
                                     Paramount Capital Investments, LLC and
                                     Paramount Capital, Inc.

Peter Morgan Kash                    Director of Paramount Capital Asset
                                     Management, Inc., Senior Managing Director,
                                     Paramount Capital, Inc.

Dr. Yuichi Iwaki                     Director of Paramount Capital Asset
                                     Management, Inc., Professor, University of
                                     Southern California School of Medicine


Item 2.

         During  the five  years  prior to the date  hereof,  none of the  above
persons  (to the best of  Paramount  Capital's  knowledge)  was  convicted  in a
criminal  proceeding  (excluding traffic violations or similar  misdemeanors) or
was a party  to a civil  proceeding  of a  judicial  or  administrative  body of
competent jurisdiction,  as a result of which such person was or is subject to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, Federal or State securities laws or finding
any violation with respect to such laws.

Items 3-6.

         Please refer to Items 3-6 herein reporting the beneficial ownership.


<PAGE>

                                    EXHIBIT C

         The name and principal  occupation or  employment,  which is located at
787 Seventh Avenue,  New York, New York,  10019, of the General Partner of Aries
Domestic is as follows:

                                                        PRINCIPAL OCCUPATION
         NAME                                               OR EMPLOYMENT
         ----                                               -------------

Paramount Capital Asset Management, Inc.                General Partner

Exhibit B is hereby incorporated by reference.

Item 2.

         During the five years prior to the date  hereof,  the above  person (to
the best of Aries  Domestic's  knowledge)  has not been  convicted in a criminal
proceeding (excluding traffic violations or similar misdemeanors) or was a party
to a  civil  proceeding  of a  judicial  or  administrative  body  of  competent
jurisdiction,  as a result of which such person was or is subject to a judgment,
decree  or final  order  enjoining  future  violations  of,  or  prohibiting  or
mandating activities subject to, Federal or State securities laws or finding any
violation with respect to such laws.

Items 3-6.

         Please refer to Items 3-6 herein reporting the beneficial ownership.

<PAGE>

                                    EXHIBIT D

         The name and principal  occupation or employment,  which in the case of
Paramount Capital Asset Management,  Inc. is located at 787 Seventh Avenue, 44th
Floor,  New York, New York,  10019,  of each  executive  officer and director of
Aries Trust is as follows:

                                                     PRINCIPAL OCCUPATION
         NAME                                            OR EMPLOYMENT
         ----                                            -------------

Paramount Capital Asset Management, Inc.             Investment Manager

MeesPierson (Cayman) Limited                         Trustee
P.O. Box 2003
British American Centre
Phase 3, Dr. Roy's Drive
George Town, Grand Cayman

         Exhibit B is hereby incorporated by reference.

Item 2.

         During the five years  prior to the date  hereof,  neither of the above
persons  (to the best of Aries  Trust's  knowledge)  have  been  convicted  in a
criminal  proceeding  (excluding traffic violations or similar  misdemeanors) or
was a party  to a civil  proceeding  of a  judicial  or  administrative  body of
competent jurisdiction,  as a result of which such person was or is subject to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, Federal or State securities laws or finding
any violation with respect to such laws.

Items 3-6.

         Please refer to Items 3-6 herein reporting the beneficial ownership.





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