MILESTONE SCIENTIFIC INC/NJ
DEF 14A, 1997-08-20
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           PROXY STATEMENT PURSUANT TO SECTION 14(A) OF THE SECURITIES
                      EXCHANGE ACT OF 1934 (AMENDMENT NO. )


Filed by the registrant  /x/
Filed by a party other than the registrant  / /

Check the appropriate box:
/ /  Preliminary Proxy Statement             / /  Confidential, for Use of
                                                  the Commission Only
/x/  Definitive Proxy Statement                   (as permitted by Rule
                                                  14a-6(e)(2))
/ /  Definitive Additional Materials
/ /  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                            Milestone Scientific Inc.
                (Name of Registrant as Specified in Its Charter)

________________________________________________________________________________
   (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of filing fee (Check the appropriate box):

/x/  No fee required.

/ / Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

(1) Title of each class of securities to which transaction applies:

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(2) Aggregate number of securities to which transaction applies:

- --------------------------------------------------------------------------------
(3) Per unit price or other underlying value of transaction computed pursuant
    to Exchange Act Rule 0-11 (Set forth the amount on which the filing fee is
    calculated and state how it was determined.):

- --------------------------------------------------------------------------------
(4) Proposed maximum aggregate value of transaction:

- --------------------------------------------------------------------------------
(5) Total fee paid:

- --------------------------------------------------------------------------------
/ / Fee paid previously with preliminary materials.

- --------------------------------------------------------------------------------
/ / Check box if any part of the fee is offset as provided by Exchange Act Rule
    0-11(a)(2) and identify the filing for which the offsetting fee was paid
    previously. Identify the previous filing by registration state-

<PAGE>

ment number, or the Form or Schedule and the date of its filing.

(1)  Amount Previously Paid:

- --------------------------------------------------------------------------------
(2)  Form, Schedule or Registration Statement No.:

- --------------------------------------------------------------------------------
(3)  Filing Party:

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(4)  Date Filed:

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                                        2
<PAGE>

                            MILESTONE SCIENTIFIC INC.

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                    TO BE HELD ON TUESDAY, SEPTEMBER 23, 1997

                                   ----------


      The Annual Meeting of  Stockholders  of Milestone  Scientific Inc. will be
held at the Hotel Inter-Continental on Tuesday, September 23, 1997 at 9:30 A.M.,
Eastern  Daylight  Savings Time, for the purpose of considering  and acting upon
the following:

     1.   Election of nine Directors.

     2.   Approval of the Company's 1997 Stock Option Plan.

     3.   Confirmation  of the appointment of Grant Thornton LLP as auditors for
          the fiscal year ending December 31, 1997.

     4.   Any and all matters incident to the foregoing, and such other business
          as may  legally  come  before  the  meeting  and any  adjournments  or
          postponements thereof.

      The Board of Director has fixed the close of business on August 1, 1997 as
the record date for determining the  stockholders  having the right to notice of
and to vote at the meeting.

                                            By order of the Board of Directors

                                            Leonard Osser
                                            Chairman of the Board

Livingston, New Jersey
August 20, 1997

- --------------------------------------------------------------------------------
IMPORTANT:     Every stockholder, whether or not he or she expects to attend the
               annual  meeting  in  person,  is urged to  execute  the proxy and
               return it promptly in the enclosed business reply envelope.

               We  shall   appreciate   your  giving  this  matter  your  prompt
               attention.
<PAGE>


                            MILESTONE SCIENTIFIC INC.

                                   ----------

                                 PROXY STATEMENT
                       FOR ANNUAL MEETING OF STOCKHOLDERS
                          TO BE HELD SEPTEMBER 23, 1997

                                   ----------

      Proxies  in the  form  enclosed  with  this  Statement  are  solicited  by
Management of Milestone  Scientific  Inc.  ("Milestone"  or the "Company") to be
used at the  Annual  Meeting  of  Stockholders  to be held at 9:30 A.M.  Eastern
Daylight  Savings Time on September 23, 1997,  for the purposes set forth in the
Notice of Meeting  and this Proxy  Statement.  Milestone's  principal  executive
offices are at 220 South Orange Avenue,  Livingston Corporate Park,  Livingston,
New  Jersey  07039.  The  approximate  date  on  which  this  Statement  and the
accompanying proxy will be mailed to Stockholders is August 20, 1997.

                          THE VOTING AND VOTE REQUIRED

      On the record date for the meeting, August 1, 1997, there were outstanding
5,568,152  shares of Common Stock of the Company (the "Common  Stock"),  each of
which will be entitled to one vote.

      Directors  are  elected by a plurality  of the votes cast at the  meeting.
Confirmation  of the  appointment  of  auditors  and  approval of the 1997 Stock
Option Plan (the "Plan") is by the  affirmative  vote of a majority of the votes
cast at the meeting.

      All shares  represented by valid proxies will be voted in accordance  with
the instructions contained therein. In the absence of instructions, proxies will
be voted FOR each of the stated  matters being voted on at the meeting.  A proxy
may be revoked  by the  stockholder  giving  the proxy at any time  before it is
voted,  either by oral or written  notice,  and a prior  proxy is  automatically
revoked by a  stockholder  giving a subsequent  proxy or attending and voting at
the  meeting.  Attendance  at the  meeting,  however,  in and of itself does not
revoke  a  prior  proxy.  In the  case  of the  election  of  directors,  shares
represented by a proxy which is marked "WITHHOLD AUTHORITY" to vote for all nine
nominees will not be counted in  determining  whether a plurality  vote has been
received for the election of directors.  Shares represented by proxies which are
marked  "ABSTAIN"  on any other  proposal  will not be  counted  in  determining
whether the  requisite  vote has been received for such  proposal.  In instances
where  brokers  are  prohibited  from  exercising  discretionary  authority  for
beneficial  owners who have not returned  proxies  ("broker  non-votes"),  those
shares will not be included  in the vote  totals  and,  therefore,  will have no
effect on the outcome of the vote.

                 SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS

      The following table shows certain  information  with respect to beneficial
ownership of the Company's Common Stock on July 28, 1997 by all persons known to
be the beneficial owners of more than 5% of its outstanding  shares,  and by all
Directors and Officers of the Company, as a group:

      NAME OF BENEFICIAL OWNER           SHARES BENEFICIALLY OWNED    % OF CLASS
      ------------------------           ------------------------     ----------
      Leonard Osser
      c/o Milestone Scientific Inc.
      220 South Orange Avenue
      Livingston Corporate Park
      Livingston, New Jersey 07039            2,395,500(1)               43.1%

      All Directors and Officers as
      a group (10 persons)                    2,699,094(2)               47.2%

- --------------
(1)  Consists of 1,586,000  held in the name of Leonard  Osser,  800,000  shares
     held in the name of U.S. Asian Consulting Group,  Inc., an affiliate of Mr.
     Osser, and 9,000 shares held by Guarantee and Trust Company for the benefit
     of U.S. Asian Consulting Group, Inc.

(2)  Includes (i) 147,500  shares subject to stock options and (ii) 5,297 shares
     subject to warrants  issued in the Company's  March 1997 Private  Placement
     financing, both exercisable within 60 days of the date hereof.

<PAGE>


                              ELECTION OF DIRECTORS

      Nine  Directors are to be elected at the Annual Meeting each for a term of
one year and until the election and qualification of a successor.

      It is intended that votes  pursuant to the enclosed proxy will be cast for
the  election  of the nine  nominees  named  below.  In the event  that any such
nominee should become unable or unwilling to serve as a Director, the Proxy will
be voted for the election of such person,  if any, as shall be designated by the
Board of Directors  (the  "Board").  Management  has no reason to believe  these
nominees will not be available for election.

      The nominees for election and certain  information about them are shown in
the following table:

<TABLE>
<CAPTION>

                                                                      SHARES
                                                                   BENEFICIALLY     PERCENT
                                                                     OWNED ON         OF     
NOMINEES FOR ELECTION                                            JULY 28, 1997 (1)   CLASS
- ---------------------                                            -----------------   -----
<S>                                                                 <C>                <C>  
LEONARD OSSER,  49, has been President,  Chief Executive  Officer
and a director  of the  Company  since July 1991.  From such date
until July 1997, he also served as the Chief Financial Officer of
the Company.  From 1980 until the  consummation  of the Company's
public  offering in November 1995, he had been primarily  engaged
as  the  principal  owner  and  Chief  Executive  of  U.S.  Asian
Consulting Group, Inc., a New Jersey based provider of consulting
services in "work-out" and  "turnaround"  situations for publicly
and privately owned companies in financial difficulty. During his
career,  Mr. Osser has provided  consulting  service for, or with
respect  to,  companies  in such  related  industries  as medical
devices,  resource  recovery and  reprocessing and waste disposal
and  a  wide  variety  of  other  industries   including  fashion
accessories, entertainment,  telecommunications,  wood processing
and securities.  While consulting for, or serving as an executive
in, the securities  industry,  Mr. Osser  structured and arranged
for  financing  and  evaluated  a large  number of  companies  in
diverse industries...............................................   2,395,000(2)       43.1%

GREGORY  VOLOK,  47, has been  Executive  Vice  President,  Chief
Operating  Officer and a director of the Company  since  December
1996.  He  initially  joined  the  Company  in March  1996 as the
President of Princeton  PMC,  Inc., a wholly owned  subsidiary of
the  Company.  For more than ten years prior  thereto,  Mr. Volok
served in various  sales and  marketing  executive  positions  of
increasing responsibility with Dentsply International,  Inc. (the
world's  largest  distributor of dental  supplies and equipment),
including serving as the executive  responsible for launching its
caulk endodontics line and the executive responsible for domestic 
sales of its Cavitron Division...................................       6,700(3)          *

GIOVANNI  MONTONCELLO,  50,  has been a director  of the  Company
since June 1995. He has been a self-employed Interior Designer in
Milan,  Italy for more than 5 years.  He has also  served  during
such period as a part-time instructor in interior design at the G.
Cova Art School in Milan, Italy....................                    20,000(4)          *

MICHAEL J. MCGEEHAN, 29, has been a Vice President of the Company
since January 1997 and a director of the Company since June 1995.
He was the Managing Director of Forefront Information Strategies,
a New Jersey  based  company  specializing  in  business  process
re-engineering  and the design  and  implementation  of  computer
database systems, from July 1994 through March 1997. In addition,
from  August 1994 to January  1995 he was a manager for  American
International  Group, a world-wide property and casualty insurer,
where he  managed  a staff of 12 data base  administrators.  From
January 1991 through July 1994, he held  positions with Microsoft
Corporation,  first as a database  specialist and network systems
engineer and then as a product manager for Microsoft Access......      20,000(4)          *
</TABLE>


                                2
<PAGE>

<TABLE>
<CAPTION>

                                                                      SHARES
                                                                   BENEFICIALLY     PERCENT
                                                                     OWNED ON         OF     
NOMINEES FOR ELECTION                                            JULY 28, 1997 (1)   CLASS
- ---------------------                                            -----------------   -----
<S>                                                                 <C>                <C>
  
DAVID  SULTANIK,  40, has been a director  of the  Company  since
January 1996. He has been the managing/administrative  partner of
the Certified Public  Accounting firm Sultanik and Krumholz,  LLC
since June 1994. For more than five years prior thereto, he was a
principal at the accounting firm Perelson, Johnson & Rones, P.C.       20,000(4)          *

STEPHEN A. ZELNICK,  59, has been a director of the Company since
January  1996.  He has  been a  partner  in the law  firm  Morse,
Zelnick,  Rose & Lander,  LLP since its inception in August 1995.
For more than five  years  prior to that he was of counsel to the
law firm Dreyer and Traub, LLP and has been  practicing  law  for
more than 30 years...............................................     150,000(5)       2.67%

PAUL GREGORY,  62, has been a director of the Company since April
1997. Mr. Gregory has been a business and insurance consultant at
Innovative  Programs  Associates Inc. and Paul Gregory Associates
since  January  1995 and  January  1986,  respectively,  where he
services,  among other entities,  foreign and domestic  insurance
groups, law and accounting firms and international  corporations.
From  January  1992 to January  1993,  Mr.  Gregory  served as an
appointed  Advisor to the  Commissioner of Insurance of the state
of  Louisiana  in  the  areas  of  liquidations,  rehabilitations,
insurance policy risk transfers and reinsurance. ................      10,150(6)          *

LOUIS I.  MARGOLIS,  53, has been a director of the Company since
April  1997.  Mr.  Margolis  has been a General  Partner  of Pine
Street Associates,  L.P., a private  investment  partnership that
invests in other  private  limited  partnerships,  since  January
1994. In January 1997, Mr.  Margolis  formed and is the President
and sole  shareholder  of Chapel Hill Capital  Corp., a financial
services  company.  From 1991 through 1993 he was a Member of the
Management  Committee of Nomura  Securities  International.  From
1993  through  1995 he was  Chairman of Classic  Capital  Inc., a
registered  investment advisor. Mr. Margolis has been a member of
the  Financial  Products  Advisory  Committee  of  the  Commodity
Futures Trading Commission since its formation in 1986, a Trustee
of the  Futures  Industry  Institute  since 1991 and a Trustee of
Saint Barnabas Hospital in Livingston, NJ since 1994.............      10,000(6)          *

LEONARD M. SCHILLER, 55, has been a director of the Company since
April 1997.  Mr.  Schiller  has been a partner in the law firm of
Schiller,  Klein & McElroy, P.C. since 1977 and has practiced law
in the State of Illinois for over 25 years.  He is also President
of The Dearborn Group, a residential property management and real
estate acquisition company. Mr. Schiller is a member of the Board
of   Directors  of  AccuMed  International,  Inc.,  a  laboratory 
diagnostic company...............................................      43,094(7)          *
</TABLE>

- ----------------

*    Less than 1%.

(1)  A person is deemed to be the  beneficial  owner of  securities  that can be
     acquired by such person  within 60 days from the filing of this report upon
     the  exercise  of  options  and  warrants  or  conversion  of   convertible
     securities.  Each beneficial owner's percentage  ownership is determined by
     assuming that options, warrants and convertible securities that are held by
     such person (but not held by any other person) and that are  exercisable or
     convertible  within  60 days  from the  filing  of this  report  have  been
     exercised  or  converted.  Except as  otherwise  indicated,  and subject to
     applicable  community  property and similar laws, each of the persons named
     has sole voting and  investment  power with  respect to the shares shown as
     beneficially owned.
(2)  Consists of 1,586,000  held in the name of Leonard  Osser,  800,000  shares
     held in the name of U.S. Asian Consulting Group,  Inc., an affiliate of Mr.
     Osser, and 9,000 shares held by Guarantee and Trust Company for the benefit
     of U.S. Asian Consulting Group, Inc.
(3)  Consists of 4,000  shares held  jointly with his wife and 2,700 shares held
     personally or in an IRA account.  
(4)  Consists of 20,000 shares  subject to stock options  exercisable  within 60
     days of the date hereof at $5.375 per share.


                                       3
<PAGE>

(5)  Includes an aggregate of 45,000 shares subject to stock options exercisable
     within  60 days of the date  hereof,  20,000 of which  are  exercisable  at
     $5.375 per share and 25,000 of which are  exercisable  at $5.125 per share,
     and 100,000 shares as to which beneficial  ownership is shared with certain
     partners not affiliated with the Company.

(6)  Includes 10,000 shares subject to stock options  exercisable within 60 days
     of the date hereof at $5.125 per share.

(7)  Includes  22,500 and 5,297 shares  subject to stock  options and  warrants,
     respectively,  exercisable  within 60 days of the date hereof at $5.125 and
     $4.72 per share, respectively.

BOARD OF DIRECTORS AND COMMITTEES

      The Board held five  meetings  and the Audit and  Compensation  Committees
held no meetings during fiscal 1996. The Audit Committee is comprised of Messrs.
Margolis,  Schiller and  Sultanik.  The  Compensation  Committee is comprised of
Messrs.  Margolis,  Sultanik and Zelnick. There is no nominating committee.  All
directors  attended  more than 75% of the  aggregate  number of  meetings of the
Board.

      The  Compensation  Committee  reviews  and  recommends  to the  Board  the
compensation and benefits of all officers of the Company, reviews general policy
matters relating to compensation  and benefits of employees of the Company,  and
administers the issuance of stock options to the Company's officers,  employees,
directors and  consultants.  The Company has agreed with the placement  agent in
its March 1997  private  placement  financing  that until  March 13,  2000,  all
compensation  arrangements  between the Company and its directors,  officers and
affiliates shall be reviewed by a compensation committee,  the majority of which
is made up of independent  directors.  The Audit Committee meets with management
and the  Company's  independent  auditors to determine  the adequacy of internal
controls and other financial reporting matters.

      THE BOARD  UNANIMOUSLY  RECOMMENDS  A VOTE FOR THE ELECTION OF EACH OF THE
NOMINEES.


                                       4
<PAGE>

                     COMPENSATION OF DIRECTORS AND OFFICERS
                               AND RELATED MATTERS

SUMMARY COMPENSATION TABLE

      The  following  Summary  Compensation  Table sets  forth all  compensation
earned,  in all capacities,  during the fiscal years ended December 31, 1995 and
1996 by (i) the Company's Chief Executive Officer and (ii) any other of the four
most highly  compensated  executive  officers  earning more than  $100,000  (the
individuals falling within categories (i) and (ii) are collectively  referred to
as  the  "Named  Executives").  Spintech,  Inc.  ("Spintech")  is  a  69%  owned
subsidiary of Milestone.

                           SUMMARY COMPENSATION TABLE

     NAME AND PRINCIPAL POSITION                    YEAR            SALARY ($)
     ---------------------------                    ----            ----------
      Leonard Osser,
      President, CEO                                1996              265,719(1)
      and CFO                                       1995               35,257(2)

      Ronald Spinello, DDS
      Chairman and Director of
      Research of Spintech(3)                       1996              126,306

- ------------------
(1)  Includes  $170,000 earned as President,  Chief Executive  Officer and Chief
     Financial  Officer of Milestone  and $95,719  earned as President and Chief
     Executive Officer of Spintech. Does not include $56,514 paid by the Company
     to Marilyn  Elson,  a certified  public  accountant who was employed by the
     Company to render accounting services. Ms. Elson is the wife of Mr. Osser.
(2)  Includes $22,885 earned as President,  CEO and COO of Milestone and $12,372
     earned as President  and CEO of Spintech.  Does not include  $4,600 paid by
     Milestone  to  Marilyn  Elson  for  book  keeping   services   rendered  as
     Comptroller  of Milestone  and $4,000 paid by Milestone  and $2,250 paid by
     Spintech to the accounting firm of Sultanik and Krumholz, LLC, one of whose
     partners was Ms. Elson.
(3)  Dr. Spinello's positions with Spintech were terminated in April 1997.


OPTION GRANTS IN FISCAL YEAR 1996 AND FISCAL YEAR-END OPTION VALUES

      No options were granted to or are  outstanding  for any Named Executive at
December 31, 1996.

EMPLOYMENT CONTRACTS

      In March 1995, the Company  entered into an employment  agreement with Mr.
Osser  which,  as amended,  provides for a term  expiring in March 2000,  with a
two-year  non-competition  period at the end of the term.  Mr. Osser must devote
substantially  all of  his  time  to  Company  business.  Under  the  employment
agreement Mr. Osser receives  compensation  at the annual rate of $170,000.  Mr.
Osser's  employment  agreement  permits him to assume  executive  positions with
subsidiaries  or other entities in which the Company has invested and to receive
additional compensation from such other entity.

      In November  1995, the Company  entered into an employment  agreement with
Ronald P.  Spinello,  D.D.S.,  providing  for his  employment  as  Chairman  and
Director of Research of Spintech  for a five-year  term  beginning  November 10,
1995 at an initial  salary of $110,000 per annum and  increasing by 10% per year
for each  succeeding  year  throughout the term. The agreement also provides for
the payment to him of up to a $500,000 bonus at the end of the employment  term,
depending on the achievement of certain profit  projections for each year of the
term. Dr. Spinello's positions with Spintech were terminated in April 1997.

      In  November  1996,  the  Company  entered  into  a  five-year  employment
agreement  with Gregory  Volok,  providing for his  employment as Executive Vice
President.  The agreement  provides for an annual base salary of $120,000 and an
18-month non-competition period at the expiration of the term.

      In November  1996, the Company  entered into an employment  agreement with
Joel D. Warady  providing for his  employment  as President and Chief  Operating
Officer of Wisdom  Toothbrush  Co., a wholly  owned  subsidiary  of the  Company
("Wisdom"),  for a three-year term at an annual base salary of $105,000.  If the
income before  Federal  income taxes of Wisdom meets certain levels in the years
1997, 1998, and 1999, Mr. Warady will receive stock 


                                       5
<PAGE>

bonuses of 5,000,  7,000 and 10,000  shares of the Common  Stock of the Company,
respectively.  The agreement also provides for non-competition at the end of the
term for six months or one year,  depending  upon the reason the  employment has
terminated.

INFORMATION ABOUT EXECUTIVE OFFICERS WHO ARE NOT ALSO DIRECTOR NOMINEES

      Joel Warady has been Vice  President of Milestone  since  January 1997 and
President of Wisdom for more than five years.


COMPENSATION OF DIRECTORS

      Non-employee  directors are granted,  upon becoming a director,  five-year
options to purchase  20,000 shares of Common Stock at an exercise price equal to
the fair market value of a share of Common Stock on the date of grant.

They receive no cash compensation.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

      During 1994 and 1995 Leonard  Osser  provided  demand loans to the Company
amounting to $44,559 and $119,000,  bearing  interest at 6% per annum. The loans
were repaid in November 1995.

      From April 1995 until February 28, 1997, Spintech leased its corporate and
administrative offices from LenRon Realty, Inc. ("LenRon"),  pursuant to a lease
expiring  March 31, 2000.  The premises  consisted of 1,500 sq. ft. on the first
and second floors of a two-story frame  building.  According to the terms of the
lease, annual rentals were to increase from $12,600 in the first year to $28,000
in the year 2000 and  Spintech  was to pay  increases  in real estate  taxes and
certain   maintenance   costs.   Spintech   leased   additional   warehouse  and
manufacturing  space from LenRon on a month-to-month  basis at $1,000 per month.
Leonard Osser  founded,  is the President and since December 1996 the sole owner
of LenRon.  On February 28, 1997,  LenRon released  Spintech from its continuing
obligations  under the lease in  anticipation  of  Spintech's  relocation to the
Company's corporate headquarters in New Jersey.

      In March 1996,  the  Company  organized  Princeton  PMC to market and sell
dental  products.  Initially,  Princeton  PMC was a joint  venture  between  the
Company and Gregory Volok. In December 1996, it became a wholly owned subsidiary
when the Company  acquired Mr.  Volok's  one-third  interest in Princeton PMC in
exchange  for 100 shares of Common  Stock and an earnout of up to an  additional
159,900 shares based on the Company's future  earnings.  At such time, Mr. Volok
became  Executive  Vice  President,  Chief  Operating  Officer and a Director of
Milestone.

      From  January 1, 1994  through  March  1997,  Spintech  rented from Ronald
Spinello,  DDS,  on a  month-to-month  basis,  at the  rate of $200  per  month,
laboratory space located in his home.

SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

      Section  16(a)  of the  Securities  Exchange  Act  of  1934  requires  the
Company's officers and directors, and persons who own more than ten percent of a
registered  class  of the  Company's  equity  securities,  to  file  reports  of
ownership and changes in ownership with the  Securities and Exchange  Commission
("SEC").  Officers,  directors  and greater than  ten-percent  stockholders  are
required by SEC  regulation  to furnish  the Company  with copies of all Section
16(a) forms they file.

      To the best of the  Company's  knowledge,  based  solely  on review of the
copies of such forms furnished to the Company, or written  representations  that
no other forms were required, the Company believes that all Section 16(a) filing
requirements  applicable to its officers and directors were complied with during
1996.

                           THE 1997 STOCK OPTION PLAN

      On March 20, 1997,  the Board  adopted the 1997 Stock  Option Plan,  which
provides,  among other matters, for incentive and non-qualified stock options to
purchase   500,000  shares  of  Common  Stock.   The  Board  proposes  that  the
stockholders  approve the Plan. The Board has granted incentive stock options to
purchase  an  aggregate  of  152,500  shares of Common  Stock to four  executive
officers,  including the Company's Chief Executive Officer,  and one employee of
the Company;  provided,  however,  that if  stockholders do not approve the Plan
within  one year  from the date of grant of these  options,  such  options  will
become  non-qualified stock options.  In addition,  the Board 


                                       6
<PAGE>

has granted to the  Company's  Chief  Executive  Officer,  pursuant to the Plan,
non-qualified  stock options to purchase  106,500  shares of Common  Stock.  The
exercise price of the options granted  pursuant to the Plan will equal or exceed
the fair market value of a share of Common Stock on the date of grant.

      The  purpose  of the  Plan  is to  provide  incentives  to  officers,  key
employees, directors,  independent contractors and agents whose performance will
contribute to the long-term success and growth of the Company, to strengthen the
ability of the Company to attract and retain officers, key employees, directors,
independent contractors and agents of high competence,  to increase the identity
of interests of such people with those of the Company's stockholders and to help
build loyalty to the Company  through  recognition and the opportunity for stock
ownership.  The Plan will be administered by the  Compensation  Committee of the
Board.

TERMS OF OPTIONS

      The  Plan  permits  the  granting  of both  incentive  stock  options  and
non-qualified stock options. Generally, the option price of both incentive stock
options and  non-qualified  stock  options must be at least equal to 100% of the
fair market  value of the shares on the date of grant.  The maximum term of each
option is ten years.  For any participant  who owns shares  possessing more than
10% of the voting  rights of the Company's  outstanding  shares of Common Stock,
the exercise price of any incentive  stock option must be at least equal to 110%
of the fair  market  value of the shares  subject to such  option on the date of
grant and the term of the  option  may not be longer  than five  years.  Options
become  exercisable at such time or times as the Board may determine at the time
it grants options.

FEDERAL INCOME TAX CONSEQUENCES

      Non-qualified Stock Options. The grant of non-qualified stock options will
have no immediate tax consequences to the Company or the employee.  The exercise
of a non-qualified stock option will require an employee to include in his gross
income the amount by which the fair market value of the  acquired  shares on the
exercise date (or the date on which any substantial  risk of forfeiture  lapses)
exceeds the option price.

      Upon a subsequent  sale or taxable  exchange of the shares  acquired  upon
exercise of a  non-qualified  stock option,  an employee will  recognize long or
short-term  capital  gain or loss  equal to the  difference  between  the amount
realized on the sale and the tax basis of such shares.

      The Company will be entitled (provided applicable withholding requirements
are met) to a deduction for Federal  income tax purposes at the same time and in
the same amount as the employee is in receipt of income in  connection  with the
exercise of a non-qualified stock option.

      Incentive Stock Options.  The grant of an incentive stock option will have
no immediate tax  consequences  to the Company or the employee.  If the employee
exercises an incentive  stock option and does not dispose of the acquired shares
within two years after the grant of the  incentive  stock  option nor within one
year  after the date of the  transfer  of such  shares to him (a  "disqualifying
disposition"),  he will realize no compensation income and any gain or loss that
he  realizes  on a  subsequent  disposition  of such shares will be treated as a
long-term  capital gain or loss.  For  purposes of  calculating  the  employee's
alternative minimum taxable income,  however,  the option will be taxed as if it
were a non-qualified stock option.

      ELIGIBILITY

      Under the Plan,  incentive  stock  options may be granted only to officers
and  employees  and  non-qualified  stock  options  may be granted to  officers,
employees as well as directors,  independent  contractors and agents.  The Board
has granted  incentive stock options and non qualified stock options to purchase
an aggregate  of 259,000  shares of Common  Stock as detailed  above;  provided,
however,  that if  stockholders do not approve the plan within one year from the
date of grant of these options, such options will all become non-qualified stock
options.  The Company has no present plans or  understandings to grant any other
Options under the Plan. Persons eligible to receive options consist primarily of
five (5) officers and twelve (12) key employees.

      The  Company  believes  that the Plan should be approved so that shares of
Common Stock are available for grant to key employees, officers and directors as
well  as  independent   contractors  and  agents  upon  whose   performance  and
contribution the long-term success and growth of the Company is dependent.

      THE BOARD UNANIMOUSLY RECOMMENDS A VOTE FOR THIS PROPOSAL.


                                       7
<PAGE>

             CONFIRMATION OF APPOINTMENT OF INDEPENDENT ACCOUNTANTS

      The Board proposes that the  stockholders  ratify the appointment of Grant
Thornton LLP as the Company's  independent  accountants for 1997. Grant Thornton
LLP were the Company's  independent  accountants  for 1996.  The report of Grant
Thornton LLP with respect to the Company's  financial  statements appears in the
Company's  Annual  Report  for the  fiscal  year  ended  December  31,  1996.  A
representative  of  Grant  Thornton  LLP  will  be  at  the  Annual  Meeting  of
Stockholders  and will have an  opportunity to make a statement if he desires to
do so and will be available to respond to  appropriate  questions.  In the event
the stockholders  fail to ratify the  appointment,  the Board will consider it a
directive to consider other accountants for a subsequent year.

      THE BOARD RECOMMENDS A VOTE FOR THIS PROPOSAL.


                                  MISCELLANEOUS

OTHER MATTERS

      Management  knows of no matter  other  than the  foregoing  to be  brought
before the Annual Meeting of  Stockholders,  but if such other matters  properly
come before the meeting,  or any adjournment  thereof,  the persons named in the
accompanying  form of proxy will vote such proxy on such  matters in  accordance
with their best judgment.

REPORTS AND FINANCIAL STATEMENTS

      Milestone's  Annual Report for the year ended  December 31, 1996 including
Audited  Financial  Statements  has been  previously  mailed.  Such  Report  and
Financial  Statements contained therein are not incorporated herein by reference
and are not considered part of this soliciting material.

      A Copy of the  Company's  Annual  Report to the  Securities  and  Exchange
Commission on Form 10-KSB, without exhibits,  will be provided without charge to
any stockholder  submitting a written request.  Such request should be addressed
to Mr. Leonard Osser,  President,  Milestone  Scientific  Inc., 220 South Orange
Avenue, Livingston Corporate Park, Livingston, New Jersey 07039.

SOLICITATION OF PROXIES

      The entire cost of the solicitation of proxies will be borne by Milestone.
Proxies  may be  solicited  by  directors,  officers  and regular  employees  of
Milestone, without extra compensation, by telephone, telegraph, mail or personal
interview.  Milestone will also reimburse brokerage houses and other custodians,
nominees and fiduciaries for their  reasonable  expenses for sending proxies and
proxy material to the beneficial owners of its Common Stock.

STOCKHOLDER PROPOSALS

      Stockholder  proposals  intended to be  presented  at the  Company's  1998
Annual  Meeting must be received by the Company for  inclusion in the  Company's
proxy  statement  relating  to that  meeting not later than May 26,  1998.  Such
proposals  should  be  addressed  to Mr.  Leonard  Osser,  President,  Milestone
Scientific Inc., 220 South Orange Avenue, Livingston Corporate Park, Livingston,
New Jersey 07039.

      EVERY  STOCKHOLDER,  WHETHER OR NOT HE OR SHE EXPECTS TO ATTEND THE ANNUAL
MEETING IN PERSON,  IS URGED TO EXECUTE  THE PROXY AND RETURN IT PROMPTLY IN THE
ENCLOSED BUSINESS REPLY ENVELOPE.

                                            By order of the Board of Directors

                                            Leonard Osser
                                            Chairman of the Board

Livingston, New Jersey
August 20, 1997


                                       8
<PAGE>

                                                                      APPENDIX A
                            MILESTONE SCIENTIFIC INC.

                             1997 STOCK OPTION PLAN

      1.  PURPOSES.  The  purposes of this Stock  Option Plan are to attract and
retain  qualified  personnel for  positions of  substantial  responsibility,  to
provide   additional   incentive  to  the   Employees  of  the  Company  or  its
Subsidiaries,  if any (as  defined  in  Section  2  below),  as  well  as  other
individuals  who perform  services for the Company or its  Subsidiaries,  and to
promote the success of the Company's business.

      Options granted  hereunder may be either  "incentive  stock  options",  as
defined in Section 422 of the  Internal  Revenue  Code of 1986,  as amended,  or
"non-qualified  stock options",  at the discretion of the Board and as reflected
in the terms of the written instrument evidencing an Option.

      2. DEFINITIONS. As used herein, the following definitions shall apply:

      (a)"BOARD" shall mean the Board of Directors of the Company.

      (b)"COMMON  STOCK"  shall mean the Common  Stock of the Company (par value
$.001 per share.)

      (c)"COMPANY" shall mean Milestone Scientific Inc., a Delaware corporation.

      (d)"COMMITTEE"  shall  mean  the  Committee  appointed  by  the  Board  of
Directors in accordance  with  paragraph (a) of Section 4 of the Plan, if one is
appointed.

      (e)"CONTINUOUS  STATUS  AS AN  EMPLOYEE"  shall  mean the  absence  of any
interruption or termination of service as an Employee.  Continuous  Status as an
Employee shall not be considered interrupted in the case of sick leave, military
leave, or any other leave of absence approved by the Board.

      (f)"EMPLOYEE"  shall mean any person,  including  officers and  directors,
employed by the Company or any Parent or Subsidiary of the Company.  The payment
of a  director's  fee by the  Company  shall  not be  sufficient  to  constitute
"employment" by the Company.

      (g)"EXCHANGE  ACT"  shall mean the  Securities  Exchange  Act of 1934,  as
amended.

      (h)"INCENTIVE  STOCK OPTION" shall mean a stock option intended to qualify
as an incentive  stock option  within the meaning of Section 422 of the Internal
Revenue Code of 1986, as amended.

      (i)"NON-QUALIFIED  STOCK OPTION" shall mean a stock option not intended to
qualify as an Incentive Stock Option.

      (j)"OPTION" shall mean a stock option granted pursuant to the Plan.

      (k)"OPTIONED STOCK" shall mean the Common Stock subject to an Option.

      (l)"OPTIONEE"  shall mean an  Employee  or other  person who  receives  an
Option.

      (m) "PARENT" shall mean a "parent  corporation",  whether now or hereafter
existing,  as defined in Section 425(e) of the Internal Revenue Code of 1986, as
amended.

      (n)"SECURITIES ACT" shall mean the Securities Act of 1933, as amended.

      (o)"SEC" shall mean the Securities and Exchange Commission.

      (p)"SHARE"  shall  mean a  share  of the  Common  Stock,  as  adjusted  in
accordance with Section 11 of the Plan.

      (q)"SUBSIDIARY"  shall mean a  "subsidiary  corporation",  whether  now or
hereafter existing, as defined in Section 425(f) of the Internal Revenue Code of
1986, as amended.

3.  STOCK.

      Subject to the provisions of Section 11 of the Plan, the maximum aggregate
number of shares which may be optioned and sold under the Plan is 500,000 shares
of Common  Stock.  If an Option should  expire or become  unexercisable  for any
reason without having been exercised in full, the unpurchased  Shares which were
subject  thereto  shall,  unless  the Plan shall  have been  terminated,  become
available for further grant under the Plan.


                                      A-1
<PAGE>

4.  ADMINISTRATION.

      (a) PROCEDURE. The Company's Board of Directors may appoint a Committee to
administer the Plan. The Committee  shall consist of not less than three members
of the Board of Directors who shall  administer  the Plan on behalf of the Board
of Directors, subject to such terms and conditions as the Board of Directors may
prescribe. Once appointed, the Committee shall continue to serve until otherwise
directed by the Board of Directors. From time to time the Board of Directors may
increase  the size of the  Committee  and appoint  additional  members  thereof,
remove members (with or without cause),  and appoint new members in substitution
therefor,  fill vacancies however caused, or remove all members of the Committee
and thereafter directly administer the Plan.

      If a majority of the Board of Directors is eligible to be granted  Options
or has been eligible at any time within the preceding  year, a Committee must be
appointed to administer  the Plan.  The Committee  must consist of not less than
three members of the Board of Directors, all of whom are "disinterested persons"
as defined in Rule 16b-3 of the General Rules and Regulations  promulgated under
the Exchange Act.

      (b) POWERS OF THE BOARD. Subject to the provisions of the Plan, the Board,
or the  Committee  shall have the  authority,  in its  discretion:  (i) to grant
Incentive Stock Options, in accordance with Section 422A of the Internal Revenue
Code of 1986,  as amended,  or to grant  Non-qualified  Stock  Options;  (ii) to
determine,  upon review of relevant  information  and in accordance with Section
8(b) of the Plan, the fair market value of the Common Stock;  (iii) to determine
the exercise price per share of Options to be granted which exercise price shall
be determined in accordance with Section 8(a) of the Plan; (iv) to determine the
persons to whom,  and the time or times at which,  Options  shall be granted and
the number of shares to be  represented  by each Option;  (v) to  interpret  the
Plan; (vi) to prescribe, amend and rescind rules and regulations relating to the
Plan;  (vii) to determine the terms and provisions of each Option granted (which
need not be identical)  and, with the consent of the holder  thereof,  modify or
amend  each  Option;  (viii) to  accelerate  or defer  (with the  consent of the
Optionee)  the  exercise  date of any Option;  (ix) to  authorize  any person to
execute on behalf of the Company any instrument required to effectuate the grant
of an  Option  previously  granted  by the  Board;  and  (x) to make  all  other
determinations deemed necessary or advisable for the administration of the Plan.

      (c)EFFECT  OF THE BOARD'S  DECISION.  All  decisions,  determinations  and
interpretations of the Board shall be final and binding on all Optionees and any
other holders of any Options granted under the Plan.

5.  ELIGIBILITY; NON-DISCRETIONARY GRANTS.

      (a) GENERAL.  Incentive  Stock  Options may be granted only to  Employees.
Non-qualified  Stock  Options may be granted to  employees  as well as directors
(subject to the limitations set forth in Section 4), independent contractors and
agents,  as determined  by the Board.  Any person who has been granted an Option
may, if he is otherwise  eligible,  be granted an additional  Option or Options.
The  Plan  shall  not  confer  upon any  Optionee  any  right  with  respect  to
continuation  of  employment  by the Company,  nor shall it interfere in any way
with his right or the Company's right to terminate his employment at any time.

      (b) LIMITATION ON INCENTIVE  STOCK OPTIONS.  No Incentive Stock Option may
be granted to an Employee if, as the result of such grant,  the  aggregate  fair
market value (determined at the time each option was granted) of the Shares with
respect to which such Incentive Stock Options are exercisable for the first time
by such  Employee  during any calendar year (under all such plans of the Company
and any  Parent  and  Subsidiary)  shall  exceed One  Hundred  Thousand  Dollars
($100,000).

      (c) NON-DISCRETIONARY  GRANTS. Each director who is not an employee of the
Company or a Subsidiary  should,  immediately upon taking office,  be granted an
option for 20,000 shares.

6. TERM OF THE PLAN.  The Plan shall become  effective upon the earlier to occur
of (i) its adoption by the Board of  Directors,  or (ii) its approval by vote of
the holders of a majority of the outstanding  shares of the Company  entitled to
vote on the  adoption of the Plan.  The Plan shall  continue in effect until May
28, 2007 unless sooner terminated under Section 13 of the Plan.

7. TERM OF OPTION. The term of each Option shall be ten (10) years from the date
of grant  hereof  or such  shorter  term as may be  provided  in the  instrument
evidencing the Option. However, in the case of an Incentive Stock Option granted
to an Employee who,  immediately  before the Incentive  Stock Option is granted,
owns stock  


                                      A-2
<PAGE>

representing  more than ten percent  (10%) of the voting power of all classes of
stock of the  Company or any  Parent or  Subsidiary,  the term of the  Incentive
Stock  Option  shall be five (5)  years  from the day of grant  thereof  or such
shorter time as may be provided in the instrument evidencing the Option.

8.  EXERCISE PRICE AND CONSIDERATION.

      (a)The per Share  exercise  price for the Shares to be issued  pursuant to
the exercise of an Option shall be such price as is determined by the Board, but
shall be subject to the following:

           (i) In the case of an Incentive Stock Option:

                  (A) granted to an Employee who,  immediately  before the grant
           of such Incentive Stock Option, owns stock representing more than ten
           percent  (10%) of the  voting  power of all  classes  of stock of the
           Company or any Parent or  Subsidiary,  the per Share  exercise  price
           shall be no less than 110% of the fair market  value per Share on the
           date of grant, as the case may be;

                  (B) granted to an Employee  not subject to the  provisions  of
           Section  8(a)(i)(A),  the per Share  exercise  price shall be no less
           than one hundred percent (100%) of the fair market value per Share on
           the date of grant.

           (ii) In the  case of a  Non-qualified  Stock  Option,  the per  Share
      exercise  price  shall be no less than one hundred  percent  (100%) of the
      fair market value per Share on the date of grant.

      (b) The  fair  market  value  shall  be  determined  by the  Board  in its
discretion;  provided,  however,  that  where  there is a public  market for the
Common  Stock,  the fair market value per Share shall be the mean of the bid and
asked  prices or, if  applicable,  the closing  price of the Common Stock on the
date of grant,  as reported by the National  Association  of Securities  Dealers
Automated  Quotation (NASDAQ) System or, in the event the Common Stock is listed
on a stock exchange,  the fair market value per Share shall be the closing price
on such  exchange  on the date of grant of the  Option,  as reported in the Wall
Street Journal.

      (c)The  consideration to be paid for the Shares to be issued upon exercise
of an Option or in payment  of any  withholding  taxes  thereon,  including  the
method of payment,  shall be determined by the Board and may consist entirely of
(i) cash,  check or promissory  note; (ii) other Shares of Common Stock owned by
the Employee  having a fair market  value on the date of surrender  equal to the
aggregate  exercise  price  of the  Shares  as to  which  said  Option  shall be
exercised;  (iii)  other  Options  owned by the  Employee  having  an  aggregate
in-the-money  value equal to the aggregate  exercise  price of the Options being
exercised  (Options are  in-the-money if the fair market value of the underlying
Shares  exceeds the exercise  price of the  Options),  (iv) an assignment by the
Employee of the net proceeds to be received  from a  registered  broker upon the
sale of the Shares or the proceeds of a loan from such broker in such amount; or
(v) any combination of such methods of payment,  or such other consideration and
method of  payment  for the  issuance  of Shares to the extent  permitted  under
Delaware Law and meeting rules and  regulations  of the SEC to plans meeting the
requirements of Section 16(b)(3) of the Exchange Act.

9.  PROCEDURES AND LIMITATIONS ON EXERCISE OF OPTIONS.

      (a) PROCEDURE FOR EXERCISE;  RIGHTS AS A  STOCKHOLDER.  Any Option granted
hereunder  shall be exercisable at such times and subject to such  conditions as
may be determined by the Board,  including  performance criteria with respect to
the Company and/or the Optionee,  and as shall be permissable under the terms of
the Plan.

           An Option may not be exercised for a fraction of a Share.

           An Option shall be deemed to be exercised when written notice of such
      exercise has been given to the Company in accordance with the terms of the
      instrument  evidencing  the Option by the person  entitled to exercise the
      Option and full payment for the Shares with respect to which the Option is
      exercised  has  been  received  by  the  Company.  Full  payment  may,  as
      authorized  by the  Board,  consist  of any  consideration  and  method of
      payment allowable under Section 8(c) of the Plan; it being understood that
      the Company shall take such action as may be reasonably required to permit
      use of an approved payment method.  Until the issuance,  which in no event
      will be delayed  more than thirty (30) days from the date of the  exercise
      of the Option,  (as evidenced by the appropriate entry on the books of the
      Company or of a duly  authorized  transfer  agent of the  Company)  of the
      stock  certificate  evidencing  such  Shares,  no right to vote or receive
      dividends or any other 


                                      A-3
<PAGE>

      rights as a  stockholder  shall exist with respect to the Optioned  Stock,
      notwithstanding the exercise of the Option. No adjustment will be made for
      a dividend  or other  right for which the record date is prior to the date
      the stock certificate is issued, except as provided in the Plan.

           Exercise of an Option in any manner shall result in a decrease in the
      number of Shares which  thereafter may be available,  both for purposes of
      the Plan and for sale  under  the  Option,  by the  number of Shares as to
      which the Option is exercised.

      (b) TERMINATION OF STATUS AS AN EMPLOYEE.  If any Employee ceases to serve
as an Employee,  he may, but only within  thirty (30) days (or such other period
of time not exceeding  three (3) months as is determined by the Board) after the
date he ceases to be an  Employee  of the  Company,  exercise  his Option to the
extent that he was  entitled to exercise it as of the date of such  termination.
To the extent that he was not  entitled  to  exercise  the Option at the date of
such termination,  or if he does not exercise such Option (which he was entitled
to exercise) within the time specified herein, the Option shall terminate.

      (c) DISABILITY OF AN EMPLOYEE.  Notwithstanding  the provisions of Section
9(b) above,  in the event an Employee is unable to continue his employment  with
the  Company as a result of his total and  permanent  disability  (as defined in
Section 105(d)(4) of the Internal Revenue Code of 1986, as amended), he may, but
only within three (3) months (or such other period of time not exceeding  twelve
(12) months as is determined by the Board) from the date of disability, exercise
his  Option to the extent he was  entitled  to  exercise  it at the date of such
disability. To the extent that he was not entitled to exercise the Option at the
date of  disability,  or if he does  not  exercise  such  Option  (which  he was
entitled  to  exercise)  within the time  specified  herein,  the  Option  shall
terminate.

      (d) DEATH OF OPTIONEE. In the event of the death of an Optionee:

           (i)  during the term of the Option who is at the time of his death an
      Employee of the Company and who shall have been in Continuous Status as an
      Employee  since  the  date of  grant  of the  Option,  the  Option  may be
      exercised,  at any time within  twelve (12) months  following  the date of
      death,  by the Optionee's  estate or by a person who acquired the right to
      exercise the Option by bequest or  inheritance,  but only to the extent of
      the right to exercise  that would have accrued had the Optionee  continued
      living one (1) month after the date of death; or

           (ii)  within  thirty  (30)  days (or such  other  period  of time not
      exceeding  three  (3)  months as is  determined  by the  Board)  after the
      termination  of  Continuous  Status  as an  Employee,  the  Option  may be
      exercised,  at any time  within  three (3)  months  following  the date of
      death,  by the Optionee's  estate or by a person who acquired the right to
      exercise the Option by bequest or  inheritance,  but only to the extent of
      the right to exercise that had accrued at the date of termination.

10.  NON-TRANSFERABILITY  OF  OPTIONS.  An  Option  may  not be  sold,  pledged,
assigned, hypothecated,  transferred, or disposed of in any manner other than by
will or by the laws of descent or distribution and may be exercised,  during the
lifetime of the Optionee, only by the Optionee.

11.  ADJUSTMENTS  UPON  CHANGES  IN  CAPITALIZATION  OR  MERGER.  Subject to any
required  action by the  stockholders  of the  Company,  the number of shares of
Common Stock  covered by each  outstanding  Option,  and the number of shares of
Common Stock which have been  authorized  for issuance  under the Plan but as to
which no Options have yet been  granted or which have been  returned to the Plan
upon  cancellation or expiration of an Option, as well as the price per share of
Common Stock covered by each such outstanding  Option,  shall be proportionately
adjusted for any  increase or decrease in the number of issued  shares of Common
Stock  resulting  from a stock  split or the  payment of a stock  dividend  with
respect to the Common  Stock or any other  increase or decrease in the number of
issued shares of Common Stock effected  without receipt of  consideration by the
Company; provided, however, that conversion of any convertible securities of the
Company  shall  not  be  deemed  to  have  been  "effected  without  receipt  of
consideration".  Such adjustment shall be made by the Board, whose determination
in that  respect  shall be final,  binding and  conclusive.  Except as expressly
provided herein,  no issuance by the Company of shares of stock of any class, or
securities  convertible into shares of stock of any class,  shall affect, and no
adjustment by reason  thereof shall be made with respect to, the number or price
of shares of Common Stock subject to an Option.


                                      A-4
<PAGE>

      In the event of the proposed dissolution or liquidation of the Company, or
in the event of a proposed sale of all or substantially all of the assets of the
Company,  or the merger of the Company  with or into  another  corporation,  the
Board of Directors of the Company shall, as to outstanding  Options,  either (i)
make appropriate provision for the protection of any such outstanding Options by
the substitution on an equitable basis of appropriate stock of the Company or of
the merged,  consolidated  or otherwise  reorganized  corporation  which will be
issuable in respect to one share of Common Stock of the Company;  provided, only
that the excess of the aggregate  fair market value of the shares subject to the
Options  immediately  after such substitution over the purchase price thereof is
not more than the  excess  of the  aggregate  fair  market  value of the  shares
subject to such Options  immediately  before such substitution over the purchase
price  thereof,  or (ii) upon written  notice to an  Optionee,  provide that all
unexercised  Options must be exercised  within a specified number of days of the
date of such notice or they will be  terminated.  In any such case, the Board of
Directors  may,  in  its  discretion,  advance  the  lapse  of  any  waiting  or
installment periods and exercise dates.

12. TIME FOR GRANTING  OPTIONS.  The date of grant of an Option  shall,  for all
purposes,  be the date on which the Board makes the determination  granting such
Option.  Notice of the  determination  shall be given to each  person to whom an
Option is so granted within a reasonable time after the date of such grant.

13.  AMENDMENT AND TERMINATION OF THE PLAN.

      (a)GENERAL. The Board may amend or terminate the Plan from time to time in
such  respects  as the Board may deem  advisable;  provided,  however,  that the
following  revisions or amendments  shall  require  approval of the holders of a
majority of the outstanding shares of the Company entitled to vote:

          (i) any  increase in the number of Shares  subject to the Plan,  other
     than in connection with an adjustment under Section 11 of the Plan;

          (ii) any change in the designation of the class of persons eligible to
     be granted options; or

          (iii) any material  increase in the benefits  accruing to participants
     under the Plan.

      (b) STOCKHOLDER  APPROVAL. If any amendment requiring stockholder approval
under  Section 13(a) of the Plan is made,  such  stockholder  approval  shall be
solicited as described in Section 17(a) of the Plan.

      (c) EFFECT OF AMENDMENT OR TERMINATION.  Any such amendment or termination
of the Plan shall not affect  Options  already  granted and such  Options  shall
remain  in full  force  and  effect  as if this  Plan  had not been  amended  or
terminated, unless mutually agreed otherwise between the Optionee and the Board,
which agreement must be in writing and signed by the Optionee and the Company.

14.  CONDITIONS UPON ISSUANCE OF SHARES.  Shares shall not be issued pursuant to
the  exercise of an Option  unless the  exercise of such Option and the issuance
and  delivery of such Shares  pursuant  thereto  shall  comply with all relevant
provisions of law, including, without limitation, the Securities Act of 1933, as
amended, the Exchange Act, the rules and regulations promulgated thereunder, and
the requirements of any stock exchange upon which the Shares may then be listed,
and shall be further  subject to the  approval of counsel  for the Company  with
respect to such compliance.

      As a condition to the  exercise of an Option,  the Company may require the
person  exercising  such Option to represent and warrant at the time of any such
exercise that the Shares are being purchased only for investment and without any
present  intention  to sell or  distribute  such  Shares  if, in the  opinion of
counsel for the Company,  such a  representation  is required by, or appropriate
under, any of the aforementioned relevant provisions of law.

15.  RESERVATION OF SHARES.  The Company,  during the term of this Plan, will at
all  times  reserve  and  keep  available  such  number  of  Shares  as shall be
sufficient to satisfy the requirements of the Plan.

      Inability  of the Company to obtain  authority  from any  regulatory  body
having  jurisdiction,  which authority is deemed by the Company's  counsel to be
necessary to the lawful issuance and sale of any Shares hereunder, shall relieve
the  Company of any  liability  in respect of the  failure to issue or sell such
Shares as to which such requisite authority shall not have been obtained.


                                      A-5
<PAGE>

16. OPTION AGREEMENT. Options shall be evidenced by written option agreements in
such form as the Board shall approve.

17. STOCKHOLDER APPROVAL.  Continuation of the Plan shall be subject to approval
by the stockholders of the Company within twelve (12) months before or after the
date the Plan is  adopted.  If such  stockholder  approval is obtained at a duly
held  stockholders'  meeting,  it may be obtained by the affirmative vote of the
holders  of a  majority  of the  outstanding  shares of the  Company  present or
represented and entitled to vote thereon.  The approval of such  stockholders of
the Company shall be (1)  solicited  substantially  in  accordance  with Section
14(a) of the Exchange Act and the rules and regulations  promulgated thereunder,
or (2)  solicited  after the  Company  has  furnished  in writing to the holders
entitled to vote substantially the same information  concerning the Plan as that
which would be required by the rules and  regulations  in effect  under  Section
14(a) of the Exchange Act at the time such information is furnished.

      If such stockholder approval is obtained by written consent in the absence
of a  Stockholders'  Meeting,  it must be obtained by the written consent of all
stockholders  of the  Company  who would have been  entitled to cast the minimum
number of votes which would be necessary  to authorize  such action at a meeting
at which all stockholders entitled to vote thereon were present and voting.

18. OTHER PROVISIONS. The Stock Option Agreement authorized under the Plan shall
contain such other provisions, including, without limitation,  restrictions upon
the exercise of the Option,  as the Board of Directors  of the  Company's  shall
deem  advisable.  Any  Incentive  Stock  Option  Agreement  shall  contain  such
limitations and restrictions  upon the exercise of the Incentive Stock Option as
shall be necessary  in order that such option will be an Incentive  Stock Option
as defined in Section 422 of the Internal Revenue Code of 1986, as amended.

19.   INDEMNIFICATION   OF  BOARD.   In  addition   to  such  other   rights  of
indemnification  as they may have as directors  or as members of the Board,  the
members of the Board shall be indemnified by the Company  against the reasonable
expenses,  including  attorneys'  fees  actually  and  necessarily  incurred  in
connection  with the defense of any action suit or proceeding,  or in connection
with any appeal  therein,  to which they or any of them may be a party by reason
of any action  taken or failure to act under or in  connection  with the Plan or
any  Option  granted  thereunder,  and  against  all  amounts  paid  by  them in
settlement  thereof  (provided such settlement is approved by independent  legal
counsel  selected by the Company) or paid by them in  satisfaction of a judgment
in any such  action,  suit or  proceeding,  except in  relation to matters as to
which it shall be adjudged in such action,  suit or  proceeding  that such Board
member is liable for negligence or misconduct in the  performance of his duties,
provided that within sixty (60) days after institution of any such action,  suit
or  proceeding  a  Board  member  shall,  in  writing,  offer  the  Company  the
opportunity, as its own expense, to handle and defend the same.

20.  OTHER  COMPENSATION  PLANS.  The  adoption of the Plan shall not affect any
other stock option or incentive  or other  compensation  plans in effect for the
Company  or any  Subsidiary,  nor  shall  the Plan  preclude  the  Company  from
establishing  any other forms of incentive or other  compensation  for employees
and directors of the Company or any Subsidiary.

21.  COMPLIANCE WITH EXCHANGE ACT RULE 16B-3. With respect to persons subject to
Section 16 of the  Exchange  Act,  transactions  under the Plan are  intended to
comply with all applicable  conditions of Rule 16b-3 or its successors under the
Exchange  Act.  To the extent any  provision  of the Plan or action by the Board
fails to so comply, it shall be deemed null and void, to the extent permitted by
law and deemed advisable by the Board.

22. SINGULAR,  PLURAL; GENDER. Whenever used herein, nouns in the singular shall
include the plural, and the masculine pronoun shall include the feminine gender.

23.  HEADINGS,  ETC., NO PART OF PLAN.  Headings of Articles and Sections hereof
are inserted for convenience and reference; they constitute no part of the Plan.


                                      A-6
<PAGE>

                           MILESTONE SCIENTIFIC INC.

           This proxy is solicited by the Board of Directors for the
                      Annual Meeting on September 23, 1997

     The undersigned  hereby appoints  Leonard Osser and Michael J. McGeehan and
each of them, with full power of substitution,  the attorneys and proxies of the
undersigned to attend the Annual Meeting of Stockholders of Milestone Scientific
Inc.  to be held on  September  23,  1997 at 9:30 a.m.,  and at any  adjournment
thereof,  hereby  revoking any proxies  heretofore  given, to vote all shares of
Common Stock of the Company held or owned by the undersigned as indicated on the
proposals  as  more  fully  set  forth  in the  Proxy  Statement,  and in  their
discretion  upon such other matters as may come before the meeting.  

1.   ELECTION OF DIRECTORS--Leonard  Osser, Gregory Volok, Giovanni Montoncello,
     Michael J.  McGeehan,  David  Sultanik,  Stephen A. Zelnick,  Paul Gregory,
     Louis I. Margolis and Leonard M. Schiller.

[ ]  FOR all nominees.

[ ]  WITHHOLD authority to vote for all nominees.  

[ ]  FOR all nominees,  EXCEPT nominee(s) written below.

     ___________________________________________________________________________

                                                         FOR   AGAINST   ABSTAIN
2.   The approval of the 1997 Stock Option Plan.         [ ]     [ ]       [ ]

3.   Confirmation of the appointment of Grant Thornton   [ ]     [ ]       [ ]
     LLP as auditors for the fiscal year ending 
     December 31, 1997.

                                  (Continued, and to be signed, on Reverse Side)
<PAGE>

     The shares  represented  by this Proxy will be voted as  directed  or if no
direction is indicated, will be voted FOR each of the proposals.

     The  undersigned  hereby  acknowledges  receipt of the Notice of, and Proxy
Statement for, the aforesaid Annual Meeting.

                                           Dated:_________________________, 1997

                                           _____________________________________

                                                   Signature of Stockholder

                                           _____________________________________
                    
                                                    Signature of Stockholder

                                           DATE AND SIGN EXACTLY AS NAME APPEARS
                                           HEREON.  EACH JOINT TENANT MUST SIGN.
                                           WHEN SIGNING AS  ATTORNEY,  EXECUTOR,
                                           TRUSTEE,  ETC.,  GIVE FULL TITLE.  IF
                                           SIGNER IS  CORPORATION,  SIGN IN FULL
                                           CORPORATE NAME BY AUTHORIZED OFFICER.




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