MILESTONE SCIENTIFIC INC/NJ
10QSB, 2000-05-15
MISCELLANEOUS MANUFACTURING INDUSTRIES
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-QSB

Mark One

|X|   QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
        SECURITIES EXCHANGE ACT OF 1934

For the Quarterly Period ended March 31, 2000

                                       OR

|_|   TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF
        THE SECURITIES EXCHANGE ACT OF 1934

For the transition period from _________ to ___________

Commission File Number 0-26284
                       -------

                            MILESTONE SCIENTIFIC INC.
                            -------------------------
             (Exact name of Registrant as specified in its charter)

              Delaware                                       13-3545623
     ---------------------------------------------------------------------
     State or other jurisdiction                          (I.R.S. Employer
     of organization)                                  Identification No.)

              220 South Orange Avenue, Livingston, New Jersey 07039
              -----------------------------------------------------
               (Address of principal executive office) (Zip Code)

                                 (973) 535-2717
                                 --------------
              (Registrant's telephone number, including area code)

      Indicate by check mark whether the Registrant (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
Registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days. Yes |X| No |_|

As of May 12, 2000 the Registrant had a total of 10,652,898 shares of Common
Stock, $.001 par value, outstanding.


                                       1
<PAGE>

Forward looking statements

When used in this Quarterly Report on Form 10-Q, the words "may", "will",
"should", "expect", "believe", "anticipate", "continue", "estimate", "project",
"intend" and similar expressions are intended to identify forward-looking
statements within the meaning of Section 27A of the Securities Act and Section
21E of the Exchange Act regarding events, conditions and financial trends that
may affect the Company's future plans of operations, business strategy, results
of operations and financial condition. The Company wishes to ensure that such
statements are accompanied by meaningful cautionary statements pursuant to the
safe harbor established in the Private Securities Litigation Reform Act of 1995.
Prospective investors are cautioned that any forward-looking statements are not
guarantees of future performance and are subject to risks and uncertainties and
that actual results may differ materially from those included within the
forward-looking statements as a result of various factors. Such forward-looking
statements should, therefore, be considered in light of various important
factors, including those set forth herein and others set forth from time to time
in the Company's reports and registration statements files with the Securities
and Exchange Commission (the "Commission"). The Company disclaims any intent or
obligation to update such forward-looking statements.


                                       2
<PAGE>

                                      INDEX

PART I.    FINANCIAL INFORMATION                                            Page

  ITEM 1.  Condensed Consolidated Financial Statements (unaudited)

           Condensed Consolidated Balance Sheets at March 31,
           2000 and December 31, 1999                                        4

           Condensed Consolidated Statements of Operations
           for the three months ended March 31, 2000 and 1999                5

           Condensed Consolidated Statements of Cash Flows
           for the three months ended March 31, 2000 and 1999                6

           Notes to Condensed Consolidated Financial Statements              8

  ITEM 2.  Management's Discussion and Analysis of Financial
           Condition and Results of Operations                               14

PART II.   OTHER INFORMATION

  ITEM 6.  Exhibits and Reports on Form 8-K                                  16

SIGNATURES                                                                   17


                                       3
<PAGE>

                          Part 1. Financial Information

ITEM 1. Condensed Consolidated Financial Statements

                   Milestone Scientific Inc. and Subsidiaries
                      CONDENSED CONSOLIDATED BALANCE SHEETS

                                     ASSETS         March 31       December 31
                                                      2000            1999
                                                  (unaudited)           *
                                                  -----------------------------
CURRENT ASSETS
  Cash and cash equivalents                       $    458,065     $    242,843
  Accounts receivable                                  470,612          297,778
  Inventories                                        1,467,668        1,717,094
  Prepaid expenses                                     161,604          192,636
                                                  ------------     ------------

      Total current assets                           2,557,949        2,450,351

PROPERTY AND EQUIPMENT, NET                          1,557,390        1,669,769

PATENTS, NET                                         1,430,585        1,491,724

OTHER ASSETS                                            10,318           10,318
                                                  ------------     ------------

      Total assets                                $  5,556,242     $  5,622,162
                                                  ============     ============

                      LIABILITIES AND STOCKHOLDERS' EQUITY

CURRENT LIABILITIES
  Accounts payable                                $  1,039,444     $    996,120
  Accrued expenses                                     146,097          246,453
                                                  ------------     ------------

      Total current liabilities                      1,185,541        1,242,573
                                                  ------------     ------------

3% SENIOR CONVERTIBLE NOTES                                 --        2,250,000
                                                  ------------     ------------

10% SENIOR CONVERTIBLE NOTES                         1,000,000               --
                                                  ------------     ------------

COMMITMENT AND CONTINGENCIES                                --               --
                                                  ------------     ------------

  STOCKHOLDERS' EQUITY
    Common stock, par value $.001; authorized,
    25,000,000 shares; 10,752,898 issued as of
    March 31, 2000 and 8,864,898 issued
    as of December 31, 1999                             10,753            8,865
  Additional paid-in capital                        33,328,987       30,877,375
  Accumulated deficit                              (29,057,523)     (27,845,135)
  Treasury stock, at cost, 100,000 shares             (911,516)        (911,516)
                                                  ------------     ------------

      Total stockholders' equity                     3,370,701        2,129,589
                                                  ------------     ------------

      Total liabilities and stockholders' equity  $  5,556,242     $  5,622,162
                                                  ============     ============

*Derived from audited financial statements at December 31, 1999

The accompanying notes are an integral part of these statements


                                       4
<PAGE>

                   Milestone Scientific Inc. and Subsidiaries

                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                      For the three months ended March 31,
                                   (unaudited)

                                                    2000               1999
                                                    ----               ----

Revenues                                        $  1,410,793       $    668,170
Cost of sales                                        639,708            499,314
                                                ------------       ------------

Gross profit                                         771,085            168,856
                                                ------------       ------------

Selling, general and
    administrative expenses                        1,635,327          1,688,464
Research and development expenses                    101,200             68,846
                                                ------------       ------------

                                                   1,736,527          1,757,310
                                                ------------       ------------

        Loss from operations                        (965,442)        (1,588,454)

Settlement costs - Spinello lawsuit                 (228,501)                --

Interest income (expense), net                       (18,445)            19,632
                                                ------------       ------------

           NET LOSS                             $ (1,212,388)      $ (1,568,822)
                                                ============       ============

Loss per share - basic and diluted              $       (.12)      $       (.18)
                                                ============       ============

Weighted average shares outstanding               10,000,063          8,717,882
                                                ============       ============

See notes to consolidated financial statements.


                                       5
<PAGE>

                   Milestone Scientific Inc. and Subsidiaries
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                      For the three months ended March 31,
                                   (unaudited)

<TABLE>
<CAPTION>
                                                                  2000            1999
<S>                                                           <C>             <C>
Cash flows from operating activities
   Net loss                                                   $(1,212,388)    $(1,568,822)
   Adjustments to reconcile net loss to
   net cash used in operating activities
     Amortization                                                  61,139          61,139
     Depreciation                                                 117,600         118,314
     Non cash portion of Settlement of Spinello lawsuit           203,500              --
   Changes in assets and liabilities
     Other assets                                                      --             606
     Accounts receivable                                         (172,834)       (109,862)
     Inventories                                                  249,426        (374,862)
     Prepaid expenses                                              31,032         (50,881)
     Accounts payable                                              43,324         310,936
     Accrued expenses                                            (100,356)        (20,355)
                                                              -----------     -----------

Net cash used in operating activities                            (779,557)     (1,633,787)
                                                              -----------     -----------

Cash flows from investing activities
     Capital expenditures                                          (5,221)        (58,625)
     Sale and (purchase) of treasury bills, net                        --       1,517,940
                                                              -----------     -----------
     Net cash provided by (used in) investing activities           (5,221)      1,459,315
                                                              -----------     -----------

Cash flows from financing activities
     Net proceeds from issuance of senior notes                 1,000,000       2,250,000
                                                              -----------     -----------
     Repayment under line of credit                                    --          50,000
     Net cash provided by financing activities                  1,000,000       2,300,000
                                                              -----------     -----------

NET INCREASE IN CASH
AND CASH EQUIVALENTS                                              215,222       2,125,528

Cash and cash equivalents at beginning of period                  242,842         316,706
                                                              -----------     -----------

Cash and cash equivalents at end of period                    $   458,065     $ 2,442,234
                                                              ===========     ===========
Supplemental disclosures of cash flow information:
   Cash paid during the period for interest                   $    27,375     $     3,931
                                                              ===========     ===========
</TABLE>

See notes to consolidated financial statements


                                       6
<PAGE>

                   Milestone Scientific Inc. and Subsidiaries
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                   For the three months ended March 31, 2000
                                   (unaudited)

Supplemental schedule of noncash financing activities:

In December 1999, the holders of 3% Convertible Notes agreed, and in February
2000 formalized the agreement to convert at a modified price of $1.25 per share,
all $2,250,000 of such notes into 1,800,000 shares common stock.


                                       7
<PAGE>

                   Milestone Scientific Inc. and Subsidiaries

                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
                                 March 31, 2000

NOTE 1 - SUMMARY OF ACCOUNTING POLICIES

      The unaudited interim financial statements of Milestone Scientific Inc.
      and Subsidiaries (the "Company") have been prepared in accordance with
      generally accepted accounting principles for interim financial
      information. Accordingly, they do not include all of the information and
      footnotes required by generally accepted accounting principles for
      complete financial statements.

      These financial statements should be read in conjunction with the
      financial statements and notes thereto for the year ended December 31,
      1999 included in the Company's Annual Report on Form 10-KSB. The
      accounting policies used in preparing these financial statements are the
      same as those described in the December 31, 1999 financial statements.

      In the opinion of the Company, the accompanying unaudited financial
      statements contain all adjustments (consisting of normal recurring
      entries) necessary to present fairly the financial position as of March
      31, 2000 and the results of operations for the three month period ended
      March 31, 2000 and March 31, 1999 and cash flows for the three month
      period ended March 31, 2000 and 1999, respectively.

      The results reported for the three month period ended March 31, 2000 are
      not necessarily indicative of the results of operations, which may be
      expected for a full year.

NOTE 2 -LIQUIDITY OF ASSETS

      The accompanying financial statements have been prepared in conformity
      with generally accepted accounting principles, which contemplate
      continuation of the Company as a going concern. However, subsequent to its
      first fiscal quarter in 1998, the Company has incurred substantial losses
      from operations. In addition, the Company has used, rather than provided,
      cash in its operations during the three months ended March 31, 2000.

      In view of the matters described in the preceding paragraph,
      recoverability of a major portion of the recorded asset amounts shown in
      the accompanying balance sheet is dependent upon continued operations of
      the Company, which in turn is dependent upon the success of the Company's
      Wand(R) product and the Company's ability to obtain necessary financing
      through January 1, 2001. The financial statements do not include any
      adjustments relating to the recoverability and classification of recorded
      asset amounts or amounts and classification of liabilities that might be
      necessary should the Company be unable to continue in existence.

      Based on management's belief that The Wand(R), is a major advance in
      dentistry and may ultimately become the accepted method for delivering
      local dental anesthesia, the Company continues to take steps aimed at
      growing and strengthening the end user base thereby gaining


                                       8
<PAGE>

      greater acceptance of The Wand(R) and translating to increased revenue
      through higher disposable handpiece usage. On October 1, 1999, the Company
      began a new sales initiative, permitting dentists in the United States to
      order the Wand(R) directly through Milestone and to avail themselves of
      certain quantity discounts when purchasing disposable handpieces and
      dental needles. During the first quarter of 2000, the Company increased
      its sales force and customer service staff. Furthermore, it continues to
      a) develop its market overseas; b) provide assistance to dental and dental
      hygiene schools which include The Wand(R) in their curriculum; c) visit,
      obtain feedback and provide further support to current Wand(R) users; d)
      distribute The Wand(R) technique videos and technical bulletins to its
      current users; and e) sell additional units to current Wand(R) users.

      As of March 31, 2000, the Company had $458,065 in aggregate cash and cash
      equivalents. Management believes that through the proper utilization of
      these existing funds, revenues generated from international distributors
      and from continued increases in domestic disposable handpiece sales,
      expense reductions achieved through cost containment programs, and the
      additional financing described below, it will have sufficient cash to meet
      its needs over the next twelve months.

      In addition, on April 5, 2000 Leonard Osser, the Chairman and CEO of the
      Company, signed an agreement which provides the Company through December
      31, 2000 with the following: 1) a $200,000 line of credit with a maturity
      of February 1, 2001 and a 9% annual interest rate; 2) payment guarantees
      on year 2000 sales to certain foreign countries through two specified
      distributors; and 3) the option, should the line of credit be
      insufficient, to defer payment of his full salary until January 3, 2001.
      Furthermore, Mr. Osser and one other participant in the February 2000
      private placement agreed to amend the Company's promissory note agreement
      so as to defer all payments including interest until January 3, 2001.
      These notes comprised $300,000 of the $1,000,000 private placement.

NOTE 3 - LOSS PER SHARE

      Basic loss per common share is computed using the weighted average number
      of common shares outstanding. Diluted loss per common share is computed
      using the weighted average common shares outstanding after giving effect
      to potential common stock from stock options based on the treasury stock
      method, plus any other potentially dilutive securities outstanding, unless
      the effect is anti-dilutive.

      For the three months ended March 31, 2000 and 1999, the assumed exercise
      of certain dilutive options and warrants were anti-dilutive. Accordingly,
      basic and diluted loss per share is based on the weighted average common
      shares outstanding.

      Options and warrants, in aggregate, to purchase 38,000 shares of common
      stock at $2.063 per share were issued to certain employees during the
      quarter ended March 31, 2000 but were not included in the computation of
      diluted earnings per share because their exercise price was greater than
      the average market price of the common shares.

      Options and warrants, in aggregate, to purchase 83,000 shares of common
      stock at $3 per share were issued in aggregate to one officer and certain
      key personnel during the three


                                       9
<PAGE>

      month ended March 31, 1999 but were not included in the computation of
      diluted loss per share because the effect would have been anti-dilutive.

NOTE 4 - LITIGATION

      Spinello Lawsuits

      On March 26, 1997, Milestone and Spintech commenced legal action in the
      United States District Court of New Jersey against Ronald Spinello, DDS,
      former Chairman and Director of Research of Spintech. In the complaint,
      plaintiffs sought recovery of compensatory and punitive damages for
      extortion and tortuous interference with existing and prospective contract
      and business relationships, a declaratory judgment that Dr. Spinello has
      no personal rights to certain technology developed while he was employed
      as Director of Research of Spintech relating to the design and production
      of ancillary components of its computer controlled local anesthetic
      delivery system, a declaratory judgment that plaintiffs have not breached
      Dr. Spinello's employment agreement or the agreement for the initial
      purchase by Milestone of a 65% equity interest in Spintech and injunctive
      relief. On May 21, 1997, Dr. Spinello filed an answer and counterclaim,
      ascertaining violation of his employment agreement and other claims. On
      May 20, 1997 Glenn R. Spinello filed a Complaint in the Court of Common
      Pleas, York County Pennsylvania which was subsequently removed to the
      United States District Court for the Middle District of Pennsylvania,
      alleging violation of his employment agreement. Milestone and Spintech
      filed an answer and counterclaims Glen Spinello's complaint.

      As a result of various pretrial motions, the only claims remaining in the
      litigation with Dr. Spinello were Milestone's claims against Dr. Spinello
      and Dr. Spinello's counterclaim for unpaid salary for the period
      subsequent to his alleged wrongful termination, and a portion of his
      indemnification claim against Spintech.

      In January 2000, prior to trial, the Company agreed to settle its claim
      against Dr. Spinello, the counterclaims asserted by Dr. Spinello and the
      claims asserted by and against Glenn Spinello. Various stipulations
      incorporating that settlement were executed in February 2000.

      Under the agreement, Dr. Spinello has assigned to Milestone any rights
      which he has to technology relating to "The Wand(R)" handpiece or
      technology developed while he was employed at Spintech and has agreed to
      cooperate in filing and to assign to Milestone any future patent
      applications covering that technology. Dr. Spinello and Glenn Spinello
      each also agreed to convey to Milestone all of his equity interests in
      Spintech. In return for the


                                       10
<PAGE>

      assignment of technology, the conveyance of Spintech equity and the
      resolution of all disputes between the parties, including the
      discontinuance with prejudice of pending legal actions, Milestone has paid
      $25,000 to Dr. Spinello and issue to him 80,000 shares or shares with a
      market value of $80,000 and to Glenn Spinello 8,000 shares.

      Class Action Lawsuit

      In 1998, several class action lawsuits were commenced against the Company,
      certain present and former executive officers, one outside director and
      consultants in the United States District Court for the District of New
      Jersey. The District Judge before whom the cases are pending has entered
      an order consolidating all of the class actions into one consolidated
      action. The Complaints contain generally overlapping and similar
      allegations of violations of the Securities Exchange Act of 1934,
      including allegations that the Company and certain of the other defendants
      violated the Act by issuing false and misleading financial statements and
      disseminating misleading statements about, among other things, the demand
      for the Company's principal product, its expected sales growth, the
      acceptance of that product by dental professionals, shipments during
      certain time periods and misrepresentations as to third-party evaluations
      of the efficacy of the product through failure to disclose the issuance of
      stock options to certain consultants. On October 22, 1998, the District
      Judge entered an order appointing lead plaintiff to represent the
      interests of all class members. On March 28, 1999, the District Judge
      appointed lead counsel to represent the class. On April 28, 1999, the
      class filed a Consolidated and Amended Class Action Complaint, naming as
      defendants the Company and three present and former executive officer and
      director. The Consolidated Complaint alleges that the Company issued false
      and misleading statements concerning, among other things, certain studies
      and reports on the Company's products, the Company's backlog and the
      amount of reserve taken for returns. Milestone believes that the material
      allegations of the Consolidated Complaint do not state a cause of action
      under the Federal Securities Law and on May 21, 1999 served a motion to
      dismiss the Consolidated Complaint for failure to state a claim. The class
      has responded to the motion and the Company filed a reply. The Motion was
      submitted to the Court in September 1999, but no decision has yet been
      rendered. Instead, on March 1, 2000, the Court held oral argument on the
      Motion to Dismiss, at the end of which the court requested supplemental
      memoranda of law on one issue. The Supplemental Memoranda Of Law were
      filed on March 16 and 22, 2000. If the Motion to Dismiss is not granted,
      the company believes that the allegations contained in the Class Action
      Complaint are without merit and it intends to vigorously defend the
      action. Specifically, Milestone believes that its financial statements
      presented fairly its results of operations, that the information which it
      has publicly disclosed did not contain any material misstatements or
      misrepresentations and that stock options issued to persons who published
      research reports were issued for other services for the Company,
      principally service as spokespersons and demonstrators of the Company's
      product. Further, the Company continues to believe that The Wand(R)
      embodies superior technology, is a major advance in dentistry and may
      ultimately become the accepted method for delivering local dental
      anesthesia.


                                       11
<PAGE>

      Derivative Action Lawsuit

      In February 1999, a purported owner of Milestone stock, commenced a
      derivative action on behalf of the Company, in the Court of Chancery of
      the State of Delaware in Newcastle County, against certain present and
      former executive officers and directors. In the action, plaintiff alleges
      that, based on the same facts as the class actions described above, the
      defendants engaged in violations of the securities laws, committed fraud
      and securities fraud, wasted corporate assets and damaged the Company's
      reputation. As a derivative action, even if the plaintiff is successful,
      any award, after deduction of plaintiff's costs and disbursements, would
      be payable to the Company. Nevertheless, Milestone believes that the
      material allegations of the complaint lack merit and intends to provide a
      legal defense for its present and former officers and directors in
      accordance with the indemnification provisions of its Certificate of
      Incorporation. Because the allegations of the Derivative Complaint are so
      closely tied to the allegations of the Class Complaint, the Derivative
      Plaintiff's counsel has agreed with the Company that no response to the
      Derivative Complaint is due until 60 days after the Court in the Class
      Action decides the motion to dismiss.

      Insurance Broker and Carrier

      In January 1999, the Company filed a complaint against its insurance
      broker (Frank Crystal Financial Services) and the two excess insurers
      [American Alliance and St. Paul] in the United States District Court for
      the District of New Jersey. American Alliance and St. Paul were in dispute
      with the Company because they claim that the Company did not timely submit
      the appropriate application. As a result, American Alliance refused to
      issue a policy and St. Paul, which issued a policy, has refused to cover
      the class actions described above. In April 1999, the Company reached a
      settlement of this action, as a result of which American Alliance issued
      the Excess Director's and Officer's Insurance Policy; the Company agreed
      that claims arising prior to the date of the policy were not covered by
      the policy and the parties reserved all of their arguments and positions
      with respect to any other coverage issues including those that resulted
      from the Consolidated and Amended Class Action Complaint referred to
      above.

      On June 24, 1999, American Alliance filed a complaint in the United States
      District Court for the Southern District of New York seeking a declaratory
      judgment that it is not liable under its policy for the claim asserted in
      the amended class complaint as well as the derivative complaint. On July
      9, 1999 the Company filed its own declaratory judgment action against
      American Alliance and St. Paul in the United States District Court for the
      District of New Jersey seeking a declaration that the claims asserted in
      the Consolidated Complaint in the Class Action and in the Derivative
      Action are covered by the Excess Director's and Officer's Insurance
      Policies. On August 4, 1999, the District Judge in New Jersey
      administratively terminated the Company's action until the previously
      filed New York Action was resolved or dismissed. Thereafter, the Company
      filed an answer in which it denied the material allegations of the
      complaint and counterclaimed in the New York Action seeking the same
      relief as it sought in its complaint in the New Jersey Action. Both
      American Alliance and the Company each requested leave from the Judge in
      the New York Action to make a motion for summary judgment and to dismiss
      the complaint, respectively.


                                       12
<PAGE>

      Instead, since any decision on the scope of coverage of the excess
      policies will, in large part, depend upon whether the Class Action
      complaint is dismissed, in whole or in part, the District Judge in the New
      York Action decided to hold in abeyance any action on American Alliance's
      complaint and Milestone's answer and counterclaim until a decision is
      rendered by the District Court in New Jersey in the Class Action.

NOTE 5 -  PRIVATE PLACEMENT

      As of February 1, 2000, the Company concluded a $1 million institutional
      private placement of 10% Senior Secured Promissory Notes due June 30, 2001
      and Warrants to purchase 142,857 shares of Milestone Common Stock with
      Cumberland Associates LLC, Strategic Restructuring Partnership L.P., a
      former principal of Cumberland Associates, two officers of the
      Corporation, an affiliate of one of its directors and six other
      individuals. The Notes are secured by all present and future inventories
      of Milestone and are prepayable out of a portion of the proceeds generated
      by sales of "Wand(R)" units. The Warrants are exercisable at prices
      increasing from $1.75 per share in the first year of $7.00 per share in
      the fifth year, subject to anti-dilution protection in the event of stock
      dividends and certain capital changes. Purchasers of the Warrants were
      granted rights to participate in certain future security offerings by
      Milestone.

      In March 1999, the Company had concluded a $2 million institutional
      private placement with Cumberland Partners, other investment funds managed
      by or affiliated with Cumberland Associates and certain principals of
      Cumberland Associates. An additional $250,000 was raised from the Chairman
      and Chief Executive Officer of Milestone, on the same terms and
      conditions. The investors purchased, at face value, 3% Senior Convertible
      Notes Due 2003, convertible into Milestone Common Stock.

      In December 1999, the holders of the 3% Convertible Notes agreed, and in
      February 2000 formalized the agreement to convert all $2,250,000 of such
      notes into common stock at a modified price of $1.25 per share. Of the
      1,800,000 shares which were to be issued, only the 200,000 shares to Mr.
      Osser are being held in escrow and pending shareholder approval.

      Since the scheduled conversion price was $2.50 per share, the Company
      recognized a non cash debt conversion expense of $731,250 in the fourth
      quarter of 1999.


                                       13
<PAGE>

ITEM 2. Management's Discussion and Analysis of Financial Condition and Results
        of Operation

      During the first quarter of 2000, the Company took significant steps to
      grow The Wand(R) ownership base and increase the daily utilization by
      domestic dentists. It dramatically increased the direct sales force and
      the Company's presence at national, regional and local trade shows as part
      of its direct sales approach.

      Additionally, the Company received approval to sell The Wand(R) and its
      disposable handpiece in Japan, $1,000,000 was raised through a private
      placement and the Spinello lawsuit was settled.

      Three month ended March 31, 2000 compared to three month ended March 31,
      1999

Statement of Operations

      Net sales for the three months ended March 31, 2000 and March 31, 1999
      were 1,410,793 and 668,170, respectively. The $742,623 increase reflects
      an approximate 100% increase in domestic sales of the Wand(R) and its
      disposable handpiece. It also includes a nearly four fold aggregate
      increase in sales to foreign distributors including Canada. The increase
      in foreign sales includes the initial shipment of 500 Wand(R) units and
      approximately 50,000 disposable handpiece to the Company's authorized
      dealer in Japan. These increases were partially offset by the $189,864 net
      sales generated from the discontinued Wisdom toothbrush line during the
      first quarter of 1999.

      Cost of sales for the three months ended March 31, 2000 and March 31, 1999
      were $639,708 and $499,134, respectively. The $140,574 increase is mainly
      attributable to an increase in Wand(R) unit and disposable handpiece sales
      volume partially offset by the recovery of approximately $120,000 in
      previously written down inventory and the $146,817 in cost of sales during
      the first quarter of 1999 which related to the discontinued Wisdom product
      line.

      For the three months ended March 31, 2000, the Company generated a gross
      profit of $771,085 or 54.7% as compared to a gross profit of $168,856 or
      25.2% for the three months ended March 31, 1999.

      Selling, general and administrative expenses for the three months ended
      March 31, 2000 and 1999 were $1,635,327 and $1,688,464, respectively. The
      $53,137 decrease is attributable to a $106,000 aggregate decrease in
      selling and marketing expenses associated with the Wand(R) and $57,400 in
      first quarter 1999 expenses related to the discontinued Wisdom products.
      This was partially offset by an aggregate increase in $30,000 increase in
      director and officer insurance and $36,000 increase in consulting
      expenses.

      Research and development cost for the three months ended March 31, 2000
      and March 31, 1999 were $101,200 and $68,846, respectively. The $32,354
      increase is primarily attributable to costs associated with the Wand(R).


                                       14
<PAGE>

      The loss from operations for the three month ended March 31, 2000 and
      March 31, 1999 were $965,442 and $1,588,454, respectively.

      The Company incurred net interest expenses of $18,445 for the three months
      ended March 31, 2000 as compared to $19,632 of net interest income for the
      same period for calendar 1999. The $38,077 difference is attributable to
      higher average borrowings in 2000 including the $1,000,000 private
      placement and interest income generated from treasury bills during the
      first quarter of 1999.

      The net loss for the three months ended March 31, 2000 was $1,212,388 as
      compared to a net loss of $1,568,822 for the quarter ended March 31, 1999.
      The $356,434 reduction in net loss is attributable to higher sales volume
      for the Wand(R) and its disposable handpiece at a higher average profit
      margin and a reduction in selling general and administrative expenses.
      This was partially offset by costs associated with the settlement of the
      Spinello lawsuit and net interest expense.

      Liquidity and Capital Resources

      At March 31, 2000, the Company's working capital was $1,372,408. It
      consisted primarily of cash generated from private placement in February
      2000 and from inventories.

      For the three month ended March 31, 2000, the Company increased cash and
      cash equivalents by $215,222.

      For the three month ended March 31, 2000, the Company's net cash used in
      operating activities was $779,557. This was primarily attributable to a
      net loss of $1,212,388 adjusted for non cash items of $61,139 for patent
      amortization, $117,600 for depreciation, and $203,500 for a lawsuit
      settlement; a $172,834 increase in accounts receivable, a $249,426
      decrease in inventory; a $31,032 decrease in prepaid expenses; a decrease
      in accrued expenses of $100,356 and a $43,324 increase in accounts
      payable.

      The Company used $5,221 in investing activities for the three month ended
      March 31, 2000. These expenditures covered retooling cost for product
      modifications.

      Financing activities provided $1,000,000 for the period. The Company, as
      described below, raised these funds through a private placement.

      As of March 31, 2000, the Company had $458,065 in aggregate cash. In
      addition, on April 5, 2000 Leonard Osser, the Chairman and CEO of the
      Company, signed an agreement which provides the Company through December
      31, 2000 with the following: 1) a $200,000 line of credit with a maturity
      of February 1, 2001 and a 9% annual interest rate; 2) payment guarantees
      on year 2000 sales to certain foreign countries through two specified
      distributors; and 3) the option, should the line of credit be
      insufficient, to defer payment of his full salary until January 3, 2001.
      Furthermore, Mr. Osser and one other participant in the February 2000
      private placement agreed to amend the Company's promissory note agreement
      so as to defer

                                       15
<PAGE>

      all payments including interest until January 3, 2001. These notes
      comprised $300,000 of the $1,000,000 private placement. Also, the Company
      continues to take steps aimed at growing and strengthening the end user
      base thereby gaining greater acceptance of The Wand(R) and translating to
      increased revenue through higher disposable handpiece usage. On October 1,
      1999, the Company began a new sales initiative, permitting dentists in the
      United States to order the Wand(R) directly through Milestone and to avail
      themselves of certain quantity discounts when purchasing disposable
      handpieces and dental needles. During the first quarter of 2000, the
      Company increased its sales and customer service staff. Furthermore, it
      continues to a) develop its market overseas; b) provide assistance to
      dental and dental hygiene schools which include The Wand(R) in their
      curriculum; c) visit, obtain feedback and provide further support to
      current Wand(R) users; d) distribute The Wand(R) technique videos and
      technical bulletins to its current users; and e) sell additional units to
      current Wand(R) users.

      In August 1999, the Company submitted an application to the FDA to market
      for medical use a similar device The Wand(R). A working prototype of an
      improved device for delivery of multi-volume anesthetic and other
      medicaments and with other added features of interest to medical
      specialists has been developed and will be submitted to the FDA.

      Private Placement

            As of February 1, 2000, the Company concluded a $1 million
      institutional private placement of 10% Senior Secured Promissory Notes due
      June 30, 2001 and Warrants to purchase 142,857 shares of Milestone Common
      Stock with Cumberland Associates, Strategic Restructuring Partnership
      L.P., a former principal of Cumberland Associates, two officers of the
      Corporation, an affiliate of one of its directors and six other
      individuals. The Notes are secured by all present and future inventories
      of Milestone and are prepayable out of a portion of the proceeds generated
      by sales of "Wand" units. The Warrants are exercisable at prices
      increasing from $1.75 per share in the first year to $7.00 per share in
      the fifth year, subject to anti-dilution protection in the event of stock
      dividends and certain capital changes. Purchasers of the Warrants were
      granted rights to participate in certain future security offerings by
      Milestone.

      Subsequent to year end, in February 2000, the holders of the 3%
      Convertible Notes agreed to convert all $2,250,000 of such notes into
      common stock at an $1.25 per share. Of the 1,800,000 shares which were to
      be issued, only the 200,000 shares to Mr. Osser are being held in escrow
      and pending shareholder approval.

Year 2000 Compliance

      The Company experienced no disruption with regards to the year 2000. It
had developed a plan which included the upgrade of its internal information
system and insured that its operating systems were compliant with the
requirements to process transactions in the year 2000. The cost was not
significant for overall compliance. The Company reviewed its own equipment and


                                       16
<PAGE>

determined that the equipment was either Year 2000 compliant or not affected by
the Year 2000 issues. Also, the Company contacted its vendors, on whom it
relies, and they too were Year 2000 complaint.

ITEM 6. EXHIBITS AND REPORTS ON FORM 8-K

(a)   Exhibits:

      Exhibit 10.21 Purchase Agreement

      Exhibit 10.22 Accord and Satisfaction of 3% Convertable Notes

(b)   Reports on Form 8-K:

      NONE


                                       17
<PAGE>

                                   Signatures

In accordance with the requirements of the Exchange Act, the registrant caused
this report to be signed on its behalf by the undersigned

                                       MILESTONE SCIENTIFIC INC.
                                       -------------------------
                                               Registrant


                                       /s/ Mitchell G. Kuhn
                                       -----------------------------------------
                                       Mitchell G. Kuhn, President and
                                       Chief Operating Officer


                                       /s/ Thomas M. Stuckey
                                       -----------------------------------------
                                       Thomas M. Stuckey, Vice President and
                                       Chief Financial Officer

Dated: May 12, 2000


                                       18



                               PURCHASE AGREEMENT

      PURCHASE AGREEMENT (this "Agreement") is made as of January 31, 2000
between MILESTONE SCIENTIFIC INC., a Delaware corporation, with its principal
offices at 220 South Orange Avenue, Livingston, New Jersey 07039 (the
"Company"), and the undersigned (each a "Purchaser" and, collectively, the
"Purchasers").

      WHEREAS, the Company is offering to sell an aggregate of $1,000,000 face
amount of its 10% Senior Secured Notes (the "Notes") and warrants to purchase
100,000 shares of Common Stock (the "Warrants"), substantially in the form
annexed hereto as Exhibits A and B, respectively; and

      WHEREAS, the Company desires to sell to Purchaser and Purchaser desires to
purchase Notes having a principal amount as is set forth on the signature page
hereof and Warrants at the rate of Warrants for 142.857 shares (rounded to the
nearest whole share) for each 1,000 face amount of the Notes being purchased.

      NOW, THEREFORE, in consideration of the premises and the covenants herein
contained, the parties hereto agree as follows:

      1. Purchase and Sale of Notes and Warrants.

            (a) Subject to the terms and conditions hereinafter set forth,
Purchaser hereby subscribes for and agrees to purchase from the Company

            (i)   Notes having the principal amount set forth on the signature
                  page hereto and

            (ii)  Warrants at the rate of Warrants for 142.857 shares (rounded
                  to the nearest whole share) for each 1,000 face amount of the
                  Notes.

The Company hereby agrees to sell Notes and Warrants in such amounts to
Purchaser.

            (b) The purchase price for the Notes and Warrants shall be an amount
equal to 100% of the stated principal amount of the Notes (the "Purchase
Price"). The Purchase Price is payable by certified or bank check made payable
to the Company or by wire transfer of funds, contemporaneously with the
execution and delivery of this Agreement. The Notes and Warrants being purchased
by Purchaser will be delivered by the Company on the Closing Date (as defined
below).

      2. Terms of the Notes and Warrants. Except as otherwise set forth in this
Agreement, the terms of the Notes and Warrants shall be as set forth in the
Notes and Warrants, respectively.

      3. Closing. The closing of the transactions contemplated hereby
("Closing") shall take place on a date (the "Closing Date") within three (3)
business days following the satisfaction of the conditions set forth herein and
at such times as shall be determined by the Company at the offices of Morse,
Zelnick, Rose & Lander, LLP, 450 Park Avenue, New York, New York 10022.

      4. Representations and Warranties of the Company. The Company hereby
represents and warrants to Purchaser, which representations and warranties shall
be true and correct as of the date hereof and as of the Closing Date, as
follows:


                                       1
<PAGE>

            4.1 Organization; Standing and Power. The Company and its
      subsidiaries (a) are corporations duly organized, existing and in good
      standing under the laws of the state of their incorporation, (b) have all
      requisite corporate power and authority to own its properties and to carry
      on their businesses as now conducted and as proposed hereafter to be
      conducted, (c) are duly qualified to do business as foreign corporations
      in each and every jurisdiction where such qualification is necessary
      except where the failure to so qualify would not have a material adverse
      effect on the financial condition, business, operations, assets or
      prospects of the Company and its subsidiaries as a whole and (d) the
      Company has all requisite corporate power and authority to execute and
      deliver, and perform all of its obligations under this Agreement.

            4.2 Capitalization. The total authorized capital stock of the
      Company consists of 25,000,000 shares of Common Stock and no shares of
      preferred stock. As of November 30, 1999, the Company has outstanding
      8,817,882 shares of Common Stock. In addition, there are 1,000,000 shares
      of Common Stock reserved for issuance under the Company's 1997 Stock
      Option Plan of which 778,000 shares are issuable pursuant to the exercise
      of outstanding stock options ranging in exercise price from $1.00 to
      $23.00 per share. The Company also has outstanding other compensatory
      options for 136,000 shares with exercise prices ranging from $5.125 to
      $23.00 per share and warrants and options in connection with financing
      transactions for 197,231 shares at exercise prices ranging from $4.72 to
      $9.00 per share of Common Stock. Except as set forth in this Section 4.2
      and except for the 3% Senior Convertible Notes, the Company does not have
      outstanding any securities convertible into or exchangeable for any shares
      of capital stock or any rights (preemptive or otherwise) to subscribe for
      or to purchase, or any options for the purchase of, or any agreements
      providing for the issuance (contingent or otherwise) of, any capital stock
      or any stock or securities convertible into or exchangeable for any
      capital stock.

            4.3 Authorization. The execution, delivery and performance by the
      Company of its obligations under this Agreement has been duly authorized
      by all requisite corporate action and will not, either prior to or as a
      result of the consummation of the transactions contemplated by this
      Agreement: (a) violate any law, any order of any court or other agency of
      government, any provision of the Certificate of Incorporation or Bylaws of
      the Company or any contract, indenture, agreement or other instrument to
      which the Company is a party, or by which the Company or any of its assets
      or properties are bound, or (b) be in conflict with, result in a breach
      of, or constitute (after the giving of notice or lapse of time or both) a
      default under, or result in the creation or imposition of any lien of any
      nature whatsoever upon any of the property or assets of any Company
      pursuant to, or result in the acceleration of, any such contract,
      indenture, agreement or other instrument. The Company is not required to
      obtain any government approval, consent or authorization from, or to file
      any declaration or statement with, any governmental instrumentality or
      agency in connection with or as a condition to the execution, delivery or
      performance of any of this Agreement other than the filings which have
      heretofore been made. This Agreement is valid, binding and enforceable
      against the Company in accordance with its terms.

            4.4 Non-contravention. To the best of its knowledge, the Company is
      not in violation or breach of or in default with respect to, complying
      with any material provision of any contract, agreement, instrument, lease,
      license, arrangement or understanding to which it is a party, and each
      such contract, agreement, instrument, lease, license, arrangement and
      understanding is in full force and effect and is the legal, valid and
      binding obligation of the Company enforceable as to the Company in
      accordance with its terms (subject to applicable


                                       2
<PAGE>

      bankruptcy, insolvency and other laws affecting the enforceability of
      creditors' rights generally and to general equitable principals). Neither
      the execution and the delivery of this Agreement, nor the consummation of
      the transactions contemplated hereby, will (a) violate any constitution,
      statute, regulation, rule, injunction, judgment, order, decree, ruling,
      charge, or other restriction of any government, governmental agency, or
      court to which the Company is subject or (b) conflict with, result in a
      breach of, constitute a default under, result in the acceleration of,
      create in any party the right to accelerate, terminate, modify, or cancel,
      or require any notice under any agreement, contract, lease, license,
      instrument, or other arrangement to which the Company is a party or by
      which the Company is bound or to which any of the Company's assets are
      subject.

            4.5 Litigation. There is no action, suit or proceeding at law or in
      equity or by or before any governmental instrumentality or other agency
      now pending or, to the knowledge of the Company, threatened in writing
      against the Company, or any of its assets, which, if adversely determined,
      might reasonably be expected to have a material adverse effect on the
      Company's business, operations and financial condition, other than as
      disclosed in its Quarterly Report on Form 10-QSB for the periods ended
      September 30, 1999.

            4.6 SEC Filings. The information set forth in the Form 10-KSB for
      the year ended December 31, 1998 and Form 10-QSB for the nine month period
      ended September 30, 1999 (collectively, the "SEC Filings") as filed by the
      Company with the Securities and Exchange Commission (the "SEC") is true,
      correct and complete in all material respects as of the respective date of
      each such filing and does not omit to state any material fact necessary in
      order to make the statements therein not misleading. The financial
      statements of the Company as set forth in the SEC Filings have been
      prepared in accordance with GAAP applied on a consistent basis throughout
      the periods covered thereby and fairly present in all material respects
      the financial condition and results of operations of the Company as of
      their respective dates. Since September 30, 1999, there has not been any
      material adverse change in the business, financial condition or results of
      operations of the Company except that the Company has continued to operate
      at a loss. Except for the liabilities set forth in the financial
      statements included in the SEC Filings and liabilities which have arisen
      after September 30, 1999 in the ordinary course of business, the Company
      has no material liability.

            4.7 Due Authorization. The issuance of the Notes has been duly
      authorized by all necessary corporate action and when issued will be the
      legal and binding obligations of the Company enforceable in accordance
      with their terms. The shares of Common Stock issuable upon exercise of the
      Warrants or in respect of interest payable on the Notes have been duly
      authorized and reserved for issuance and, when issued in accordance with
      the terms of the Warrants or issued in respect of interest payable on the
      Notes, as applicable, will be fully paid and non-assessable, free and
      clear of any restrictions on transfer (other than any restrictions under
      the Securities Act of 1933, as amended (the "Securities Act") and state
      securities laws), taxes, security interests, options, warrants, purchase
      rights, contracts, commitments, equities, claims, and demands.

            4.8 Securities Law Exemption. Assuming the accuracy of Purchaser's
      representations and warranties set forth herein, the sale of the Notes and
      Warrants pursuant to this Agreement has been made in accordance with the
      provisions and requirements of Regulation D ("Regulation D") or ss.4(6)
      under the Securities Act and any applicable state law.


                                       3
<PAGE>

            4.9 Use of Proceeds. The proceeds from the sale of the Notes and
      Warrants will be used for working capital.

            4.10 Compliance with Laws. The Company is in compliance in all
      material respects with all occupational safety, health, wage and hour,
      employment discrimination, environmental, flammability, labeling, usury
      and other applicable laws which are material to its businesses, and the
      Company is not aware of any state of facts, events, conditions or
      occurrences which may now or hereafter constitute or result in a violation
      of any of such applicable laws, or which may give rise to the assertion of
      any such violation, the effect of which could have a material adverse
      effect on the Company's business, operations and financial condition.

            4.11 Licenses and Permits. The Company has obtained all federal,
      state and local licenses and permits required to be maintained in
      connection with and material to its operations, and all such licenses and
      permits obtained are valid and in full force and effect.

            4.12 Existing Registration Rights. Except for the Registration
      Rights Agreement referred to in Section 7 hereof and the registration
      rights given to the holders of the Company's 3% Senior Convertible Notes,
      the Company is not a party to any agreement under which it is obligated to
      register any of its securities under the Securities Act.

            4.13 Patents, Trademarks, Copyrights, Etc. The Company owns or
      validly licenses all patents, patent rights, patent applications,
      licenses, shop rights, trademarks, trademark applications, tradenames,
      copyrights and other proprietary information (collectively "Rights") used
      in the conduct of its business as currently being conducted. To the actual
      knowledge of the Company, the conduct of its business as currently being
      conducted does not conflict with valid rights of others in any way, nor
      has any material use been made of the Rights, except by the Company or by
      other entities duly licensed to use the same.

            4.14 No Other Representations. The Company shall not be deemed to
      have made any representations, warranties, covenants, agreements or
      indemnifications pertaining to the subject matter of this Agreement,
      whether express or implied, except to the extent that such
      representations, warranties, covenants, agreements or indemnifications are
      made in this Agreement or the Schedules hereto or in any certificate or
      other agreement, document or instrument delivered pursuant to the
      provisions of this Agreement.

      5. Representations and Warranties of the Purchasers. The Purchaser hereby
represents and warrants to the Company, which representations and warranties
shall be true and correct as of the date hereof and the Closing Date, as
follows:

            5.1 Authorization of Agreement. The execution, delivery and
      performance of this Agreement has been duly authorized by all necessary
      action on the part of Purchaser, does not violate any laws or regulations
      applicable to Purchaser and is the valid binding and enforceable
      obligation of Purchaser in accordance with its terms.

            5.2 Non-contravention. Neither the execution and the delivery of
      this Agreement, nor the consummation of the transactions contemplated
      hereby, will (a) violate any constitution, statute, regulation, rule,
      injunction, judgment, order, decree, ruling, charge, or other restriction
      of any government, governmental agency, or court to which Purchaser is
      subject or (b) conflict with, result in a breach of, constitute a default
      under, result in the acceleration of, create in any


                                       4
<PAGE>

      party the right to accelerate, terminate, modify, or cancel, or require
      any notice under any agreement, contract, lease, license, instrument, or
      other arrangement to which Purchaser is a party or by which Purchaser is
      bound or to which any of Purchaser's assets are subject.

            5.3 Accredited Investor. Purchaser is an "accredited investor" as
      that term is defined in Rule 501(a) of the Securities Act, and the rules
      promulgated thereunder.

            5.4 Investment. Purchaser acknowledges that this offering of Notes
      and Warrants has not been reviewed by the United States Securities and
      Exchange Commission ("SEC") and that the sale of the Notes and Warrants
      pursuant hereto is intended to be a nonpublic offering pursuant to
      Sections 4(2), 4(6) or 3(b) of the Securities Act. Purchaser represents
      that the Notes or Warrants are being purchased for his own account, for
      investment and not for distribution or resale to others. Purchaser agrees
      that Purchaser will not sell or otherwise transfer the Notes, Warrants or
      the shares of the Common Stock issuable upon exercise of the Warrants
      unless such securities, as the case may be, are registered under the
      Securities Act or unless an exemption from such registration is available.
      Purchaser understands that neither the Notes, Warrants nor the shares of
      Common Stock issuable upon exercise of the Warrants have been registered
      under the Securities Act and they are or will be issued pursuant to a
      specific exemption from the registration provisions of the Securities Act
      which depends upon, among other things, the bona fide nature of the
      investment intent as expressed herein.

            5.5 Access to Data. Purchaser has been given copies of the SEC
      Filings and has had an opportunity to review same. Purchaser has had an
      opportunity to discuss the SEC Filings and the Company's business,
      management and financial affairs with the Company's management and the
      opportunity to review the Company's facilities, each to Purchaser's
      satisfaction. Purchaser understands that such discussions, as well as any
      written information issued or provided by the Company, were intended to
      describe the aspects of the Company's business and prospects which the
      Company believes to be material but were not necessarily a thorough or
      exhaustive description thereof.

            5.6 Speculative Nature of Investment. Purchaser acknowledges that
      the purchase of the Notes and Warrants involves a high degree of risk and
      that (i) an investment in the Company is highly speculative and only
      investors who can afford the loss of their entire investment should
      consider investing in the Company and purchasing Notes and Warrants; (ii)
      Purchaser may not be able to liquidate his investment; (iii)
      transferability of the Notes, Warrants and the shares of Common Stock
      issuable upon exercise of the Warrants is extremely limited; and (iv)
      Purchaser could sustain the loss of his entire investment.

            5.7 Experience. Purchaser acknowledges that he has prior investment
      experience, including investment in non-listed and non-registered
      securities, or has employed the services of an investment advisor,
      attorney or accountant to review all of the documents furnished or made
      available by the Company and to evaluate the merits and risks of such an
      investment on Purchaser's behalf.

            5.8 Lack of Liquidity. Purchaser understands that there is no public
      market for the Notes or Warrants.

            5.9 Legends. Purchaser consents to the placement of a legend on the
      Notes, Warrants, and shares of Common Stock issued on exercise of the
      Warrants, provided they are not


                                       5
<PAGE>

      then covered by an effective Registration Statement, all as set forth in
      Section 6 of this Agreement.

            5.10 Address. Purchaser hereby represents that the address of
      Purchaser furnished by him at the end of this Agreement is Purchaser's
      principal residence if Purchaser is an individual or Purchaser's principal
      business address if it is a corporation or other entity.

            5.11 Registered Representative. Purchaser acknowledges that if he is
      a Registered Representative of a National Association of Securities
      Dealers, Inc. ("NASD") member firm, he must give such firm the notice
      required by the NASD Conduct Rules, or any applicable successor rules of
      the NASD receipt of which must be acknowledged by such firm on the
      signature page hereof.

            5.12 No Other Representations. Purchaser hereby represents that,
      except as set forth herein, no representations or warranties have been
      made to the Purchaser by the Company or any agent, employee or affiliate
      of the Company and in entering into this transaction, Purchaser is not
      relying on any information, other than that contained herein, that
      contained in the SEC Filings and the results of independent investigation
      by the Purchaser. The Purchaser shall not be deemed to have made any
      representations, warranties, covenants, agreements or indemnifications
      pertaining to the subject matter of this Agreement, whether express or
      implied, except to the extent that such representations, warranties,
      covenants, agreements or indemnifications are made in this Agreement or
      the Schedules hereto or in any certificate or other agreement, document or
      instrument delivered pursuant to the provisions of this Agreement.

            5.13 Purpose. If Purchaser is a partnership, corporation, trust or
      other entity, it was not formed for the purpose of investing in the
      Company.

            5.14 No Broker. There is no firm, corporation, agency or other
      entity or person that is entitled to a finder's fee or any type of
      commission in relation to or in connection with the transactions
      contemplated by this Agreement as a result of any agreement or
      understanding with Purchaser or any of its directors, officers, employees
      or agents.

            6. Legends. The Notes and Warrants shall be endorsed with the
      following legend:

      THIS SECURITY HAS BEEN ACQUIRED FOR INVESTMENT PURPOSES ONLY AND MAY NOT
      BE SOLD, TRANSFERRED OR OTHERWISE DISPOSED OF UNTIL (I) A REGISTRATION
      STATEMENT UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT") SHALL
      HAVE BECOME EFFECTIVE WITH RESPECT THERETO OR (II) RECEIPT BY THE COMPANY
      OF AN OPINION OF COUNSEL REASONABLY SATISFACTORY TO THE COMPANY TO THE
      EFFECT THAT REGISTRATION UNDER THE ACT IS NOT REQUIRED IN CONNECTION WITH
      SUCH PROPOSED TRANSFER NOR IS IN VIOLATION OF ANY APPLICABLE STATE
      SECURITIES LAWS. THIS LEGEND SHALL BE ENDORSED UPON ANY NOTE ISSUED IN
      EXCHANGE FOR THIS NOTE.

      THIS SECURITY IS SUBJECT TO THE TERMS OF A PURCHASE AGREEMENT, DATED AS OF
      JANUARY 31, 2000, A COPY OF WHICH IS ON FILE AT THE EXECUTIVE OFFICES OF
      MILESTONE SCIENTIFIC INC.


                                       6
<PAGE>

      7. Registration Rights. The Company and the Purchaser will enter into a
registration rights agreement, substantially in the form annexed hereto as
Exhibit C.

      8. Confidentiality. Purchaser covenants and agrees that none of Purchaser,
his agents and representatives will use for their own benefit, convey or
disclose to any third party any information provided by the Company concerning
its current or proposed business, operations and financial conditions, other
than information which is already publicly available, was already known to
Purchaser or is obtained from a source other than the Company and to the extent
required by law.

      9. Covenants.

            9.1 Affirmative Covenants of the Company. The Company covenants and
      agrees that, from the date hereof and until the Notes have been paid in
      full, it shall:

                  (a) Corporate. Do or cause to be done all things necessary to
            at all times (a) other than mergers solely among the Company and any
            of its subsidiaries, preserve, renew and keep in full force and
            effect its corporate existence, patents, trademarks, rights,
            licenses, permits and franchises, (b) comply with this Agreement,
            (c) maintain and preserve all of its material property used or
            useful in the conduct of their respective businesses, and (d) comply
            with all applicable laws material to its businesses, including the
            reporting requirements of the Securities Exchange Act of 1934,
            whether now in effect or hereafter enacted, promulgated or issued.

                  (b) Notice of Proceedings. Give prompt written notice to the
            Purchaser of any proceeding instituted against the Company in any
            federal or state court or before any commission or other regulatory
            body, whether federal, state or local, which, if adversely
            determined, could have a material adverse effect upon their
            business, operations, properties, assets or condition, financial or
            otherwise when taken as a whole.

                  (c) Books and Records; Inspection. Maintain true and accurate
            books and records respecting all of their business operations, and
            permit agents or representatives of the Purchasers to inspect, at
            any time during normal business hours, upon reasonable notice, and
            without undue material disruption of their business operations, all
            of such books and records and to visit the properties and operations
            of the Company and consult with the employees and officers of the
            Company.

                  (d) Notice of Default or Material Adverse Change. Promptly
            advise the Purchaser of any event which could have a material
            adverse effect on the Company's business, operation, property,
            assets or condition, financial or otherwise, or the existence or
            occurrence of any Event of Default (as defined in the Notes), any
            breach of this Section 9.1 or Section 9.2 or any default of the
            Company under any agreement or instrument to which it is a party.

                  (e) Notice of Filings with SEC. Promptly advise the Purchaser
            of any filing of a registration statement under the Securities Act
            with the SEC covering any of the Company's securities.


                                       7
<PAGE>

                  (f) Delivery of Financial Statements and other Reports. The
            Company will deliver to each holder of Notes promptly upon
            transmission thereof, copies of all financial statements,
            information circulars, proxy statements and reports as the Company
            shall send to its stockholders and copies of all registration
            statements, prospectuses and all reports which it shall file with
            the Securities and Exchange Commission or with any securities
            exchange on which any of its securities is listed or with NASDAQ and
            copies of all press releases and other statements made available to
            the public concerning material developments in the business of the
            Company.

                  (g) Stock to be Reserved. The Company covenants that all
            shares of Common Stock that may be issued upon exercise of the
            Warrants or in respect of interest payable on the Notes will, upon
            issuance, be validly issued, fully paid and nonassessable and free
            from all taxes, liens and charges with respect to the issuance
            thereof. The Company covenants that during the period in which the
            Warrants are outstanding it will at all times have authorized and
            reserved a sufficient number of shares of Common Stock to permit the
            exercise of the Warrants.

            9.2 Negative Covenants of the Company. The Company covenants and
      agrees that, until the Notes have been paid in full, unless the holders of
      Notes representing more than 50% of the aggregate principal amount of the
      Notes (the "Requisite Majority") shall otherwise consent in writing, the
      Company shall not directly or indirectly:

                  (a) Restrictions on Debt and Certain Payments. Incur, create,
            assume or suffer to exist any indebtedness that shall be senior to
            or pari passu with (in right of payment) the Notes other than: (i)
            any purchase money obligations incurred by the Company in connection
            with the purchase of property in the ordinary course of business;
            (ii) all payment obligations of the Company pursuant to any
            capitalized lease entered into by the Company; (iii) all payables
            incurred by the Company in the ordinary course of its business; and
            (iv) the Company's 3% Senior Convertible Notes. The Company will not
            prepay any indebtedness or redeem any securities junior to, or pari
            passu with, the Notes.

                  (b) Restrictions on Liens. Create, assume or suffer to exist
            any lien upon any of its property or assets except (i) liens for
            taxes which are not yet due or are being contested in good faith,
            (ii) statutory liens of landlords and liens of carriers,
            warehousemen, mechanics and materialmen incurred in the ordinary
            course of business and (iii) liens made through purchase money
            security interests in the ordinary course of business.

                  (c) Registration and other Rights. Enter into any agreement
            with respect to its securities which is contrary to or inconsistent
            with the rights granted to the holders of Notes in the Registration
            Rights Agreement, this Agreement,the Notes or the Warrants.

      10. Conditions Precedent to the Obligations of the Company. The
obligations of the Company pursuant to this Agreement are subject to the
satisfaction at the Closing of each of the following conditions; provided,
however, that the Company may, in its sole discretion, waive any of such
conditions and proceed with the transactions contemplated hereby.


                                       8
<PAGE>

            10.1 Accuracy of Representations and Warranties. The representations
      and warranties of the Purchaser contained in this Agreement or in any
      document or certificate delivered in connection with the transactions
      contemplated hereby shall be true and correct in all material respects on
      and as of the Closing Date, as if made on and as of the Closing Date.

            10.2 Performance of Agreements. Each Purchaser shall have duly
      executed and delivered this Agreement to the Company and shall have
      performed and complied in all material respects with all covenants,
      obligations and agreements to be performed or complied with by any of them
      on or before the Closing Date pursuant to this Agreement.

      11. Conditions Precedent to the Obligations of the Purchasers. The
obligations of a Purchaser under this Agreement is subject to the satisfaction
at the Closing of each of the following conditions; provided, however, that a
Purchaser may, in such Purchaser's sole discretion, waive any of such conditions
and proceed with the transactions contemplated hereby.

            11.1 Accuracy of Representations and Warranties. The representations
      and warranties of the Company contained in this Agreement or in any
      document or certificate delivered in connection with the transactions
      contemplated hereby shall be true and correct in all material respects on
      and as of the Closing Date, as if made on and as of the Closing Date.

            11.2 Performance of Agreements. The Company shall have duly executed
      and delivered this Agreement and the Registration Rights Agreement and
      shall have performed and complied in all material respects with all
      covenants, obligations and agreements to be performed or complied with by
      it on or before the Closing Date pursuant to this Agreement.

            11.3 Litigation, Material Changes, Defaults, etc. No claim, action,
      suit, proceeding, arbitration or hearing or notice of hearing shall be
      pending (and no action or investigation by any governmental authority
      shall be threatened) which seeks to enjoin, prevent or adversely affect
      the consummation of the transactions contemplated by this Agreement. There
      shall not have been any changes in the business of the Company which have
      or could reasonably be expected to have a material adverse effect on the
      business, operations, properties, assets or condition, financial or
      otherwise, of the Company. There shall exist no defaults under the
      provisions of any instrument evidencing indebtedness of the Company.

            11.4 Officers and Secretary's Certificate. The Purchaser shall have
      received a certificate of the chief executive officer and the chief
      financial officer of the Company, dated the Closing Date, certifying as to
      the fulfillment of the conditions set forth in Sections 11.1, 11.2 and
      11.3 and a certificate of the Company's Secretary certifying copies of the
      Company's Certificate of Incorporation, By-laws and all resolutions
      authorizing the transactions contemplated herein and certifying as to the
      incumbency of officers executing this Agreement and any related document.

            11.5 Good Standing Certificates. The Purchaser shall have received
      (a) "good standing" certificate with respect to the Company from the
      Secretary of State of Delaware stating that the Company is duly
      incorporated and in good standing in Delaware, and (b) a certificate from
      the Secretary of State of New Jersey to the effect that the Company is
      duly qualified to do business in New Jersey as a foreign corporation.


                                       9
<PAGE>

            11.6 Legal Opinion. The Purchaser shall have received an opinion
      from counsel to the Company substantially in the form annexed hereto as
      Exhibit C.

            11.7 Purchase Permitted by Applicable Laws. The purchase of and
      payment for the Notes and Warrants shall not be prohibited by any
      applicable law or governmental regulation (including without limitation
      Regulations G, T and X of the Board of Governors of the Federal Reserve
      System) and shall not subject the holders of the Notes and Warrants to any
      tax, penalty or liability under any applicable law or governmental
      regulation.

            11.8 Simultaneous Closing. The Purchaser shall be required to close
      only if the Company simultaneously closes on the sale of Notes in the
      aggregate face amount of $700,000 and Warrants at the rate set forth in
      Section 1(a).

      12. General Provisions.

            12.1 Survival of Representations, Warranties, Covenants, and
      Agreements. The representations, warranties, covenants and agreements
      contained in this Agreement shall survive the execution of this Agreement.

            12.2 Notices. All notices, requests, demands and other
      communications which are required to be or may be given under this
      Agreement to any party to any of the other parties shall be in writing and
      shall be deemed to have been duly given when (a) delivered in person, (b)
      the day following dispatch by an overnight courier service (such as
      Federal Express or UPS, etc.) or (c) five (5) days after dispatch by
      certified or registered first class mail, postage prepaid, return receipt
      requested, to the party to whom the same is so given or made. Any notice
      or other communication given hereunder shall be addressed to the Company,
      at its principal offices as set forth above and to the Purchaser at his
      address indicated on the signature page hereto.

            12.3 Counterparts. This Agreement may be executed in two or more
      counterparts, each of which shall be deemed an original and all of which
      together shall constitute one and the same instrument.

            12.4 Headings. All headings are inserted for convenience of
      reference only and shall not affect the meaning or interpretation of any
      such provisions or of this Agreement, taken as an entirety.

            12.5 Severability. If and to the extent that any court of competent
      jurisdiction holds any provision (or any part thereof) of this Agreement
      to be invalid or unenforceable, such holding shall in no way affect the
      validity of the remainder of this Agreement.

            12.6 Changes, Waivers, Etc. Subject to Section 12.11, neither this
      Agreement nor any provision hereof may be changed, waived, discharged or
      terminated orally, but rather may only be changed by a statement in
      writing signed by the party against which enforcement of the change,
      waiver, discharge or termination is sought. It is agreed that a waiver by
      either party of a breach of any provision of this Agreement shall not
      operate, or be construed, as a waiver of any subsequent breach by that
      same party.

            12.7 Governing Law. This Agreement shall be governed by and
      construed in accordance with the laws of the State of New York. The
      parties hereby agree that any dispute

                                       10
<PAGE>

      which may arise between them arising out of or in connection with this
      Agreement shall be adjudicated before a court located in New York City and
      they hereby submit to the exclusive jurisdiction of the courts of the
      State of New York located in New York, New York and of the federal courts
      in the Southern District of New York with respect to any action or legal
      proceeding commenced by any party, and irrevocably waive any objection
      they now or hereafter may have respecting the venue of any such action or
      proceeding brought in such a court or respecting the fact that such court
      is an inconvenient forum, relating to or arising out of this Agreement or
      any acts or omissions relating to the sale of the securities hereunder,
      and consent to the service of process in any such action or legal
      proceeding by means of registered or certified mail, return receipt
      requested, in care of the address set forth below or such other address as
      the undersigned shall furnish in writing to the other.

            12.8 Binding Effects. This Agreement shall be binding upon and inure
      to the benefit of the parties hereto and their respective successors,
      legal representatives and assigns.

            12.9 Entire Agreement. This Agreement sets forth the entire
      agreement and understanding between the parties as to the subject matter
      thereof and incorporates and supersedes all prior discussions, agreements
      and understandings of any and every nature among them.

            12.10 Further Assurances. The parties agree to execute and deliver
      all such further documents, agreements and instruments and take such other
      and further action as may be necessary or appropriate to carry out the
      purposes and intent of this Agreement.

            12.11. Waivers and Amendments. With the written consent of the
      Requisite Majority, the obligations of the Company under this Agreement
      may be waived (either generally or in a particular instance and either
      retroactively or prospectively), and with the same consent the Company may
      enter into a supplementary agreement for the purpose of adding any
      provisions to this Agreement or to any supplemental agreement or modifying
      in any manner the rights and obligations of the holders of the Notes and
      of the Company; provided, however, that no such waiver or supplemental
      agreement shall reduce the aforesaid percentage of holders of the Notes
      who are required to consent to any waiver or supplemental agreement
      without the consent of all of the holders of the Notes. Notwithstanding
      anything to the contrary above, the payment of interest, time of payment
      of interest, the interest rate payable, payment of principal and time of
      payment of principal on the Notes may not be changed without the written
      consent of holders then holding at least 80% of the outstanding principal
      amount of the Notes, and this provision may not be waived or amended
      without the written consent of holders then holding at least 80% of the
      outstanding principal amount of the Notes. Written notice of any such
      waiver, consent or agreement of amendment, modification or supplement
      shall be given by the Company to holders of the Notes who have not
      previously consented thereto in writing.

            12.12. Expenses. Each party hereto shall pay all of its own fees and
      expenses in connection with the transactions contemplated hereby;
      provided, however, the Company shall pay the legal fees incurred by
      Purchasers to Willkie Farr & Gallagher in connection with the
      transactions contemplated hereby to the extent such legal fees do not
      exceed $15,000 in the aggregate, plus the disbursements of such legal
      counsel.

      IN WITNESS WHEREOF, the parties have executed this Agreement as of the day
and year first above written.


                                       11
<PAGE>



                                       MILESTONE SCIENTIFIC INC.


                                       By: _____________________________________
                                              Leonard Osser, Chairman and
                                              Chief Executive Officer

PURCHASER:


____________________________________


                                       12



            AGREEMENT dated as of the 31st of January, 2000 between Milestone
Scientific, Inc. ("Milestone") and the undersigned holders of Milestone's
outstanding 3% Convertible Notes.

      1. Milestone hereby agrees to allow each of the undersigned holders of its
3% Convertible Notes to convert such Notes at $1.25 per share, i.e. one half of
the present conversion price, and each of the undersigned agrees to submit his
Notes to Milestone for conversion at that price not later than February 29,
2000.

      2. Each of the undersigned acknowledges that one half of the shares to be
issued on conversion of the Notes have not been registered under the Securities
Act of 1933, as amended, are being acquired for investment without a view to
distribution and will bear a suitable legend to such effect. Milestone hereby
agrees that the Shares issued on conversion of the Notes which are not presently
covered by a Registration Statement shall be deemed to be included within the
definition of "Registerable Securities" set forth in that certain Registration
Rights Agreement between Milestone and the undersigned and shall enjoy all of
the registration rights and other benefits provided for in such Registration
Rights Agreement.

            IN WITNESS WHEREOF the parties have executed this document as of the
day and year first above written.


                                       MILESTONE SCIENTIFIC INC.


                                       By: _____________________________________
                                              Leonard Osser, Chairman and
                                              Chief Executive Officer

     Name                                           Face Amount of 3%   No. of
                                                    Shares Convertible Notes
                                                    to be Converted
                                                       $

     ____________________________________


<TABLE> <S> <C>


<ARTICLE>                     5

<S>                             <C>
<PERIOD-TYPE>                   3-MOS
<FISCAL-YEAR-END>                               DEC-31-2000
<PERIOD-START>                                  JAN-01-1999
<PERIOD-END>                                    MAR-31-2000
<CASH>                                              458,065
<SECURITIES>                                              0
<RECEIVABLES>                                       470,612
<ALLOWANCES>                                              0
<INVENTORY>                                       1,467,668
<CURRENT-ASSETS>                                  2,557,949
<PP&E>                                            1,557,390
<DEPRECIATION>                                            0
<TOTAL-ASSETS>                                    5,556,242
<CURRENT-LIABILITIES>                             1,185,541
<BONDS>                                                   0
                                     0
                                               0
<COMMON>                                             10,753
<OTHER-SE>                                        3,359,948
<TOTAL-LIABILITY-AND-EQUITY>                      5,556,242
<SALES>                                           1,410,793
<TOTAL-REVENUES>                                  1,410,793
<CGS>                                               639,708
<TOTAL-COSTS>                                             0
<OTHER-EXPENSES>                                  1,965,028
<LOSS-PROVISION>                                          0
<INTEREST-EXPENSE>                                   18,445
<INCOME-PRETAX>                                  (1,212,388)
<INCOME-TAX>                                              0
<INCOME-CONTINUING>                              (1,212,388)
<DISCONTINUED>                                            0
<EXTRAORDINARY>                                           0
<CHANGES>                                                 0
<NET-INCOME>                                     (1,212,388)
<EPS-BASIC>                                           (0.12)
<EPS-DILUTED>                                         (0.12)



</TABLE>


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