BIOCIRCUITS CORP
SC 13D, 1997-04-25
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                         UNITED STATES
              SECURITIES AND EXCHANGE COMMISSION
                    Washington, D.C.  20549

                          SCHEDULE 13D

            Under the Securities Exchange Act of 1934
                    (Amendment No. ______)*

                    Biocircuits Corporation                 
     ______________________________________________________
                        (Name of Issuer)

               Common Stock, $0.001 Par Value
      ______________________________________________________
                 (Title of Class of Securities)

                         09058W200
               ____________________________________
                         (CUSIP Number)
     Austin W. Marxe, 153 East 53rd Street, 51st fl., NY NY 10022
                         (212) 832-5300
      ______________________________________________________
     (Name, Address and Telephone Number of Person Authorized to
               Receive Notices and Communications)          

                         April 15, 1997
     _________________________________________________________
     (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule
13G to report the acquisition which is the subject of this
Schedule 13D, and is filing this schedule because of Rule 13d-
I(b)(3) or (4), check the following box ___.

Note: Six copies of this statement, including all exhibits,
should be filed with the Commission.  See Rule 13d-1(a) for other
parties to whom copies are to be sent.

*The remainder of this cover page shall be filled out for a
reporting person's initial filing on this form with respect to
the subject class of securities, and for any subsequent amendment
containing information which would alter the disclosures provided
in a prior cover page.

The information required in the remainder of the cover page shall
not be deemed to be "filed" for the purpose of Section 18 of the
Securities Exchange Act of 1934 ("Act") or otherwise subject to
the liabilities of that section of the Act but shall be subject
to all other provisions of the Act (however, see the Notes).




                    SCHEDULE 13D

CUSIP No. 09058W200                      Page  2  of  9 Pages
- ----------------------------------------------------------------
(1)  NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     Special Situations Fund III, L.P.  
     F13-3737427
     MGP Advisers Limited Partnership *
     F13-3263120
- ----------------------------------------------------------------
(2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*  (a) | |
                                                        (b) |X|
- ----------------------------------------------------------------
(3)  SEC USE ONLY

- ----------------------------------------------------------------
(4)  SOURCE OF FUNDS*   00
________________________________________________________________
(5)  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
PURSUANT TO 2(d) OR 2(e)                               ____
_________________________________________________________________
(6)  CITIZENSHIP OR PLACE OF ORGANIZATION
     Delaware
- ----------------------------------------------------------------
 NUMBER OF     (7) SOLE VOTING POWER   See Marxe/Greenhouse
  SHARES       -------------------------------------------------
BENEFICIALLY   (8) SHARED VOTING POWER             None
 OWNED BY      -------------------------------------------------
   EACH        (9) SOLE DISPOSITIVE POWER  See Marxe/Greenhouse  
  REPORTING     ------------------------------------------------
PERSON WITH    (10) SHARED DISPOSITIVE POWER        None
- ----------------------------------------------------------------
(11)  AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON
     811,875 Shares (including 408,125 Warrants)
- ----------------------------------------------------------------
(12) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*
- ----------------------------------------------------------------
(13) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     5.9
- ----------------------------------------------------------------
(14) TYPE OF REPORTING PERSON*
     IV/IA
- ----------------------------------------------------------------
* AWM Investment Company, Inc., a Delaware corporation is the
General Partner of this entity.






                         SCHEDULE 13D

CUSIP No. 09058W200                    Page  3   of  9 Pages
- ----------------------------------------------------------------
(1)  NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     Special Situations Private Equity Fund, L.P. 
     F13-3916551
     MG Advisers, L.L.C. F13-3916549
- ----------------------------------------------------------------
(2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*  (a) | |
                                                        (b) |X|
- ----------------------------------------------------------------
(3)  SEC USE ONLY

- ----------------------------------------------------------------
(4)  SOURCE OF FUNDS* 00
 ________________________________________________________________
(5)  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
PURSUANT TO 2(d) OR 2(e)                               ____
_________________________________________________________________
(6)  CITIZENSHIP OR PLACE OF ORGANIZATION
     Delaware
- ----------------------------------------------------------------
 NUMBER OF     (7) SOLE VOTING POWER  See Marxe/Greenhouse
  SHARES       -------------------------------------------------
BENEFICIALLY   (8) SHARED VOTING POWER             None
 OWNED BY      -------------------------------------------------
   EACH        (9) SOLE DISPOSITIVE POWER  See Marxe/Greenhouse
 REPORTING     -------------------------------------------------
PERSON WITH    (10) SHARED DISPOSITIVE POWER        None
- ----------------------------------------------------------------
(11)  AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON
   208,126 shares (including 114,792 Warrants)
- ----------------------------------------------------------------
(12) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*
- ----------------------------------------------------------------
(13) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     1.5  
- ----------------------------------------------------------------
(14) TYPE OF REPORTING PERSON*

     IV/IA
- ----------------------------------------------------------------








                    SCHEDULE 13D

CUSIP No. 09058W200                      Page  4   of  9 Pages
- ----------------------------------------------------------------
(1)  NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     Special Situations Cayman Fund, L.P.  ("CAY")
     98-0132442
     AWM Investment Company, Inc. 11-3086452
- ----------------------------------------------------------------
(2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*  (a) | |
                                                        (b) |X|
- ----------------------------------------------------------------
(3)  SEC USE ONLY

- ----------------------------------------------------------------
(4)  SOURCE OF FUNDS*  00
________________________________________________________________
(5)  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
PURSUANT TO 2(d) OR 2(e)                               ____
_________________________________________________________________
(6)  CITIZENSHIP OR PLACE OF ORGANIZATION
     Cayman Islands 
- ----------------------------------------------------------------
 NUMBER OF     (7) SOLE VOTING POWER  See Marxe/Greenhouse
  SHARES       -------------------------------------------------
BENEFICIALLY   (8) SHARED VOTING POWER             None
 OWNED BY      -------------------------------------------------
   EACH        (9) SOLE DISPOSITIVE POWER See Marxe/Greenhouse   
  REPORTING     ------------------------------------------------
PERSON WITH    (10) SHARED DISPOSITIVE POWER        None
- ----------------------------------------------------------------
(11)  AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON
   425,000 Shares (including 212,500 Warrants)
- ----------------------------------------------------------------
(12) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*

- ----------------------------------------------------------------
(13) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
     3.1
- ----------------------------------------------------------------
(14) TYPE OF REPORTING PERSON*
     IV/IA
- ----------------------------------------------------------------







          
                         SCHEDULE 13D

CUSIP No. 09058W200                     Page  5  of  9 Pages
- ----------------------------------------------------------------
(1)  NAME OF REPORTING PERSON
     S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

     Austin W. Marxe ###-##-####
     David M. Greenhouse ###-##-####
- ----------------------------------------------------------------
(2)  CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*  (a) | |
                                                        (b) |X|
- ----------------------------------------------------------------
(3)  SEC USE ONLY

- ----------------------------------------------------------------
(4)  SOURCE OF FUNDS* 00
________________________________________________________________
(5)  CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
PURSUANT TO 2(d) OR 2(e)                               ____
_________________________________________________________________
(6)  CITIZENSHIP OR PLACE OF ORGANIZATION
     United States of America 
- ----------------------------------------------------------------
 NUMBER OF     (7) SOLE VOTING POWER            1,445,001
  SHARES       -------------------------------------------------
BENEFICIALLY   (8) SHARED VOTING POWER             None
 OWNED BY      -------------------------------------------------
   EACH        (9) SOLE DISPOSITIVE POWER       1,445,001
 REPORTING     -------------------------------------------------
PERSON WITH    (10) SHARED DISPOSITIVE POWER        None
- ----------------------------------------------------------------
(11)  AGGREGATE AMOUNT BENEFICALLY OWNED BY EACH REPORTING PERSON

   1,445,001 Shares (including 735,417 Warrants)
- ----------------------------------------------------------------
(12) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
     CERTAIN SHARES*

- ----------------------------------------------------------------
(13) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
        10.2
- ----------------------------------------------------------------
(14) TYPE OF REPORTING PERSON*

     IN
- ----------------------------------------------------------------







                                        Page  6 of  9 Pages

Item 1.   Security and Issuer.  This Schedule relates to Units of
          Biocircuits Corporation (the "Issuer"), each consisting
          of one share of Common Stock and one warrant (exercise
          price of $0.75 per share) to purchase one share of
          Common Stock (collectively, the "Securities").  The
          Issuer's principal executive offices are located at
          1324 Chesapeake Terrace, Sunnyvale, CA 94089.

Item 2.   Identity and Background.  This Schedule is filed on
          behalf of (i) Special Situations Fund III, L.P., a
          Delaware limited partnership ("SSF III"); (ii) Special
          Situations Private Equity Fund, L.P., a Delaware
          limited partnership (the "Private Equity Fund"); (iii)
          Special Situations Cayman Fund, L.P., a Cayman Islands
          limited partnership (the "Cayman Fund"); (iv) MGP
          Advisers Limited Partnership , a Delaware limited
          partnership ("MGP"); (v) MG Advisers. L.L.C., a New
          York limited liability company ("MG"); (vi) AWM
          Investment Company, Inc., a Delaware corporation
          ("AWM"); (vii) Austin W. Marxe and (viii) David
          Greenhouse.  Each of the foregoing is hereinafter
          referred to, individually, as a "Reporting Person" and,
          collectively, as the "Reporting Persons."
          
          The principal office and business address of the
          Reporting Persons, other than the Cayman Fund, is 153
          East 53rd Street, 51st floor, New York, NY  10022.  The
          principal office and business address of the Cayman
          Fund is c/o CIBC Bank and Trust Company (Cayman)
          Limited, CIBC Bank Building, P. O. Box 694, Grand
          Cayman, Cayman Islands, British West Indies.

          The principal business of SSF III, the Private Equity
          Fund and the Cayman Fund (individually, a "Fund" and,
          collectively, the "Funds") is to invest in equity and
          equity related securities.  The principal business of
          MGP is to act as the general partner of and the
          investment adviser to SSF III.  The principal business
          of MG is to act as general partner of and the
          investment adviser to the Private Equity Fund. The
          princiap business of AWM is to act as the general
          partner of MGP and as the general partner of and the
          investment adviser to the Cayman Fund.  MGP, MG, and
          AWM are referred to herein, individually, as an
          "Adviser" and, collectively, as the "Advisers."  The
          principal occupation of Austin W. Marxe and David
          Greenhouse, both of whom are United States citizens, is
          to serve as officers, directors and members or
          principal shareholders of the Advisers. 



                                        Page 7 of 9 Pages

          Neither any Fund, any Adviser, Austin W. Marxe nor
          David Greenhouse, during the last 5 years, has been
          convicted in any criminal proceeding or was or is
          subject to a judgement, decree or final order enjoining
          future violations of, or prohibiting or mandating
          activities subject to, Federal or state securities laws
          or finding any violations with respect to such laws. 

Item 3.   Source and Amount of Funds or Other Consideration.
          Each Fund utilized available cash assets to purchase
          the Securities. 

Item 4.   Purpose of the Transaction.  Each of the Reporting
          Persons has acquired and is holding the Securities
          solely for investment purposes and not with the purpose
          or the effect of changing or influencing control of the
          Issuer.  Each Fund acquired the Securities in the
          ordinary course of business and is holding such
          Securities for the benefit of its third party
          investors. 
          
Item 5.   Interest in Securities of the Issuer.  See pps. 2-5 of
          this Schedule, setting forth the aggregate number and
          percentage of the Securities beneficially owned by each
          Reporting Person, the number of shares as to which
          there is sole or shared power to vote, or to direct the
          vote, and sole or shared power to dispose or to direct
          the disposition.
          
          On April 15, 1997, the following Funds acquired the
          following Securities in a private placement transaction
          directly from the issuer at a price per Unit of $1.00:

          1.  SSF III --                255,000 Units
          2.  Private Equity Fund --    212,500 Units
          3.  Cayman Fund --             63,750 Units

          Within the last 60 days, the following Funds disposed
          of the following shares of Common Stock in open market
          trades:

          1.  SSF III --
          3/4/97    30,000 shares at a price of $1.75 per share
          3/10/97    5,000 shares at a price of $1.75 per share
          3/18/97   12,500 shares at a price of $1.375 per share
          3/20/97   25,000 shares at a price of $1.375 per share






                                        Page 8 of 9 Pages

          2.  Cayman Fund --

          3/4/97    95,000 shares at a price of $1.75 per share
          3/10/97   15,000 shares at a price of $1.75 per share
          3/11/97   10,000 shares at a price of $1.9375 per share
          3/18/97   37,500 shares at a price of $1.375 per share
          
Item 6.   Contracts, Arrangements, Understandings or
          Relationships with Respect to Securities of the Issuer. 
          See Item 2 and Item 4 of this Schedule.  Based on such
          Items. Messrs. Marxe and Greenhouse maintain sole
          voting power and sole dispositive power with respect to
          the Securities. 

Item 7.   Material to be Filed as Exhibits. 
          None

          After reasonable inquiry and to the best of my
          knowledge and belief, I certify that the information
          set forth in this statement is true, complete and
          correct.


April 25, 1997

                    /s/ Austin W. Marxe
                    --------------------------------
                    Special Situations Fund III, L.P.
                    by: Austin W. Marxe, Managing Director
               

                    /s/ Austin W. Marxe
                    _________________________________
                    Special Situaitons Private Equity Fund, L.P.
                    by: Austin W. Marxe, Managing Director
     

          
                    /s/ Austin W. Marxe
                    _____________________________
                    Special Situations Cayman Fund,L.P.        
                    by: Austin Marxe, Managing Director        


                    /s/ Austin W. Marxe
                    _____________________________
                    MGP Advisers Limited Partnership           
                    by: Austin Marxe, President and CEO




                                        PAge 9 of 9 Pages
                    

                    /s/ Austin W. Marxe
                    _____________________________
                    MG Advisers, L.L.C.                        
                    by: Austin Marxe, President and CEO        
                              
                    /s/ Austin W. Marxe
                    _____________________________
                    AWM Investment Company, Inc.               
                    by: Austin Marxe, President and CEO

                              


                    /s/ Austin W. Marxe
                    _____________________________
                    Austin W. Marxe                            


                    /s/ David Greenhouse
                    _____________________________
                    David Greenhouse                           




                                   






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