NORTH AMERICAN VACCINE INC
424B3, 1997-04-04
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
 
           PROSPECTUS SUPPLEMENT TO PROSPECTUS DATED NOVEMBER 5, 1996
 
                                U.S.$86,250,000
              6.50% CONVERTIBLE SUBORDINATED NOTES DUE MAY 1, 2003
 
     This Prospectus Supplement supplements the Prospectus dated November 5,
1996 (as supplemented, the "Prospectus") relating to the offering for resale of
the 6.50% Convertible Subordinated Notes (the "Notes") issued under an
Indenture, dated May 7, 1996, between North American Vaccine, Inc. (the
"Company") and Marine Midland Bank, as Trustee (the "Trustee"), and the shares
of common stock, no par value ("Common Shares"), of the Company issuable upon
conversion of the Notes. The Notes were issued and sold (the "Original
Offering") on May 7, 1996 (the "Original Offering Date") to the Underwriters (as
defined) and were simultaneously sold by the Underwriters, in transactions
exempt from the registration requirements of the Securities Act of 1933, as
amended (the "Securities Act"), in the United States to persons reasonably
believed by the Underwriters to be qualified institutional buyers as defined in
Rule 144A under the Securities Act, to a limited number of institutional
investors that are accredited investors within the meaning of Rule 501(a) under
the Securities Act and outside the United States to non-U.S. persons in offshore
transactions in reliance on Regulation S under the Securities Act.
 
     The Notes and the Common Shares issuable upon conversion of the Notes (the
"Offered Securities") may be offered and sold from time to time by the holders
of the Offered Securities or by their transferees, pledgees, donees or their
successors (collectively, the "Selling Holders") pursuant to the Prospectus. The
Offered Securities may be sold by the Selling Holders from time to time directly
to purchasers or through agents, underwriters or dealers. See "Selling Holders."
If required, the names of any such agents or underwriters involved in the sale
of the Offered Securities and the applicable agent's commission, dealer's
purchase price or underwriter's discount, if any, will be set forth in a
supplement to the Prospectus. The Selling Holders will receive all of the net
proceeds from the sale of the Offered Securities and will pay all underwriting
discounts and selling commissions, if any, applicable to any such sale. The
Company is responsible for payment of all other expenses incident to the offer
and sale of the Offered Securities. The Selling Holders and any broker/dealers,
agents or underwriters that participate in the distribution of the Offered
Securities may be deemed to be "Underwriters" within the meaning of the
Securities Act, and any commission received by them and any profit on the resale
of the Offered Securities purchased by them may be deemed to be underwriting
commissions or discounts under the Securities Act.
 
     The Notes are convertible into Common Shares at any time prior to the close
of business on the maturity date, unless previously redeemed or repurchased, at
a conversion price of $24.858 per share (equivalent to a conversion rate of
40.2293 shares per $1,000 principal amount of Notes), subject to adjustment in
certain events. On April 2, 1997, the last reported sale price of the Common
Shares, which are listed on the American Stock Exchange ("AMEX") under the
symbol "NVX," was $19 1/2 per share. For a detailed description of the Notes,
including the payment of interest, redemption and subordination, see
"Description of Notes" in the Prospectus.
 
     PROSPECTIVE INVESTORS SHOULD CAREFULLY CONSIDER THE MATTERS DISCUSSED UNDER
THE CAPTION "RISK FACTORS" COMMENCING ON PAGE 7 OF THE PROSPECTUS.
 
     THESE SECURITIES HAVE NOT BEEN APPROVED OR DISAPPROVED BY THE SECURITIES
AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION NOR HAS THE
SECURITIES AND EXCHANGE COMMISSION OR ANY STATE SECURITIES COMMISSION PASSED
UPON THE ACCURACY OR ADEQUACY OF THIS PROSPECTUS SUPPLEMENT. ANY REPRESENTATION
TO THE CONTRARY IS A CRIMINAL OFFENSE.
 
            THE DATE OF THIS PROSPECTUS SUPPLEMENT IS APRIL 4, 1997.
<PAGE>   2
 
                                SELLING HOLDERS
 
     The Notes were originally issued by the Company and sold by Goldman Sachs
International and UBS Securities LLC (the "Underwriters"), in transactions
exempt from the registration requirements of the Securities Act, to persons
reasonably believed by such Underwriters to be "qualified institutional buyers"
(as defined in Rule 144A under the Securities Act), to a limited number of
institutional investors that are accredited investors within the meaning of Rule
501(a) of the Securities Act, or outside the United States to non-U.S. persons
in offshore transactions in reliance on Regulation S under the Securities Act.
The Selling Holders may from time to time offer and sell pursuant to the
Prospectus any or all of the Notes and Common Shares issued upon conversion of
the Notes. The term Selling Holder includes the holders listed herein and in any
additional Prospectus Supplement and the beneficial owners of the Notes and
their transferees, pledgees, donees or other successors. Any such additional
Prospectus Supplement will contain certain information with respect to the
Selling Holders and the respective aggregate principal amount of Notes
beneficially owned by each Selling Holder that may be offered pursuant to the
Prospectus. Such information will be obtained from the Selling Holders and the
Trustee.
 
     The following table sets forth, as of a recent practicable date, certain
information with respect to the Selling Holders and the respective principal
amounts of Offered Securities beneficially owned by each Selling Holder that may
be offered pursuant to the Prospectus. Such information has been obtained from
the Selling Holders.
 
<TABLE>
<CAPTION>
                                                   PRINCIPAL
                                                   AMOUNT OF    COMMON SHARES
                                     PRINCIPAL       NOTES       OWNED PRIOR    COMMON SHARES
                                     AMOUNT OF      OFFERED          TO            OFFERED
      NAME OF SELLING HOLDER        NOTES OWNED     HEREBY       OFFERING(1)      HEREBY(2)
- ----------------------------------  -----------   -----------   -------------   -------------
<S>                                 <C>           <C>           <C>             <C>
Catholic Mutual Relief Society of
  America.........................  $   100,000   $   100,000         4,022           4,022
Catholic Mutual Relief Society of
  America Retirement Plan and
  Trust...........................      150,000       150,000         6,034           6,034
ZaZove Convertible Fund, L.P......      500,000       500,000        20,114          20,114
Lincoln National Life Insurance...    5,605,000     5,605,000       225,480         225,480
Lincoln National Convertible
  Securities Fund.................    2,460,000     2,460,000        98,962          98,962
Weirton Trust.....................      670,000       670,000        26,953          26,953
United National Insurance
  Company.........................      115,000       115,000         4,626           4,626
Julius Baer Securities Inc.
  on Behalf of Premier Global
  Yield
  Plus Fund.......................      400,000       400,000        16,091          16,091
Boston Harbor Trust Co., N.A......      350,000       350,000        14,079          14,079
Och-Ziff Capital Management,
  L.P.............................      600,000       600,000        63,937          24,137
Declaration of Trust for the
  Defined Benefit Plan of ZENECA
  Holdings Inc....................      640,000       640,000        25,746          25,746
Thermo Electron Balanced
  Investment Fund.................      875,000       875,000        35,200          35,200
Hillside Capital Incorporated
  Corporate Account...............      350,000       350,000        14,080          14,080
Declaration of Trust for the
  Defined Benefit Plan of ICI
  American Holdings Inc...........      950,000       950,000        38,217          38,217
Delaware State Employees'
  Retirement Fund.................    3,290,000     3,290,000       132,352         132,352
General Motors Employees Domestic
  Group Trust.....................    8,900,000     8,900,000       358,034         358,034
</TABLE>
 
                                       S-2
<PAGE>   3
 
<TABLE>
<CAPTION>
                                                   PRINCIPAL
                                                   AMOUNT OF    COMMON SHARES
                                     PRINCIPAL       NOTES       OWNED PRIOR    COMMON SHARES
                                     AMOUNT OF      OFFERED          TO            OFFERED
      NAME OF SELLING HOLDER        NOTES OWNED     HEREBY       OFFERING(1)      HEREBY(2)
- ----------------------------------  -----------   -----------   -------------   -------------
<S>                                 <C>           <C>           <C>             <C>
Highbridge Capital Corporation....  $ 2,500,000   $ 2,500,000       100,571         100,571
UBS Securities LLC................      720,000       720,000        38,964          28,964
Putnam Convertible Income-Growth
  Trust...........................    4,530,000     4,530,000       182,235         182,235
Putnam Health Sciences Trust......    1,400,000     1,400,000        56,319          56,319
Putnam Balanced Retirement Fund...      275,000       275,000         8,045           8,045
Museum of Fine Arts, Boston.......      105,000       105,000         4,223           4,223
Boston College Endowment..........      245,000       245,000         9,855           9,855
Promutual.........................      540,000       540,000        21,723          21,723
Hartford Fire Insurance Company...      525,000       525,000        21,119          21,119
Employers Reinsurance
  Corporation.....................      500,000       500,000        20,114          20,114
Putnam Convertible Opportunities
  and Income Trust................      480,000       480,000        19,309          19,309
New Hampshire State Retirement
  System..........................      645,000       645,000        25,947          25,947
Boston Harbor Trust Co., N.A......      350,000       350,000        15,537          14,079
Atlantic Trust Co., N.A...........        5,000         5,000           201             201
HBK Main Street Investments L.P...    2,760,000     2,760,000       111,030         111,030
HBK Securities Ltd. c/o HBK
  Investments.....................    1,430,000     1,430,000        57,526          57,526
OCM Convertible Trust.............    1,705,000     1,705,000        68,590          68,590
OCM Convertible Limited
  Partnership.....................       80,000        80,000         3,218           3,218
Delta Air Lines Master Trust......    1,155,000     1,155,000        46,464          46,464
State Employees' Retirement Fund
  of the State of Delaware........      475,000       475,000        19,109          19,109
State of Connecticut Combined
  Investment Funds................    1,435,000     1,435,000        57,728          57,728
Goldman, Sachs & Co. .............    1,442,000     1,442,000        58,009          58,009
Walker Art Center.................      250,000       250,000        10,057          10,057
                                    -----------   -----------   -------------   -------------
SUBTOTAL..........................   49,507,000    49,507,000     2,039,820       1,988,562
Unnamed holders of Offered
  Securities or any future
  transferees, pledgees, donees or
  successors of or from any such
  unnamed holder (3)..............   36,743,000    36,743,000     1,478,116(4)    1,478,116
                                    -----------   -----------   -------------   -------------
          TOTAL...................  $86,250,000   $86,250,000     3,517,936       3,466,678(5)
                                    ============  ============  =============   =============
</TABLE>
 
- ---------------
(1) Includes Common Shares as to which the Selling Holder has sole or shared
     voting or investment power and Common Shares issuable pursuant to options
     and/or warrants exercisable within the next 60 days. Also includes the
     Common Shares into which the Notes held by such Selling Holder are
     convertible at the initial conversion rate. The conversion rate and the
     number of Common Shares issuable upon conversion of the Notes are subject
     to adjustment under certain circumstances. Accordingly, the number of
     Common Shares issuable upon conversion of the Notes may increase or
     decrease from time to time.
(2) Assumes conversion into Common Shares of the full amount of Notes held by
     the Selling Holder at the initial conversion rate and the offering of such
     shares by such Selling Holder
 
                                       S-3
<PAGE>   4
 
     pursuant to the Registration Statement of which the Prospectus forms a
     part. The conversion rate and the number of Common Shares issuable upon
     conversion of the Notes is subject to adjustment under certain
     circumstances. Accordingly, the number of Common Shares issuable upon
     conversion of the Notes may increase or decrease from time to time.
     Fractional shares will not be issued upon conversion of the Notes; rather,
     cash will be paid in lieu of fractional shares, if any.
(3)  No such holder may offer Notes or Common Shares that have been issued upon
     conversion of the Notes pursuant to the Registration Statement of which the
     Prospectus forms a part until such holder is included as a Selling Holder
     in a supplement to the Prospectus in accordance with the Registration
     Rights Agreement.
(4)  Assumes that the unnamed holders of Offered Securities or any future
     transferees, pledgees, donees, or successors of or from any such unnamed
     holder do not beneficially own any Common Shares other than the Common
     Shares issuable upon conversion of the Notes at the initial conversion
     rate.
(5)  Due to rounding, the total of this column may not exactly equal the
     aggregate number of Common Shares issuable upon conversion of the Notes at
     the initial conversion rate.
 
     None of the named Selling Holders has, or within the past three years has
had, any position, office or other material relationship with the Company or its
affiliates. Because the Selling Holders may, pursuant to the Prospectus, offer
all or some portion of the Notes or the Common Shares issuable upon conversion
of the Notes, no estimate can be given as to the principal amount of the Notes
or the number of Common Shares issuable upon conversion of the Notes that will
be held by the Selling Holders upon termination of any such sales. In addition,
the Selling Holders identified above may have sold, transferred or otherwise
disposed of all or a portion of their Notes, since the date on which they
provided the information regarding their holdings of Notes, in transactions
exempt from the registration requirements of the Securities Act. Selling Holders
that wish to transfer pursuant to the Registration Statement of which the
Prospectus forms a part the Notes or Common Shares issuable upon conversion of
the Notes must complete and sign a Notice of Transfer Pursuant to Registration
Statement in substantially the form of Appendix A attached hereto.
 
     Information concerning the Selling Holders may change from time to time and
any such changed information will be set forth in supplements to the Prospectus
if and when necessary. In addition, the per share conversion price, and,
therefore, the number of Common Shares issuable upon conversion of the Notes, is
subject to adjustment under certain circumstances. Accordingly, the number of
Common Shares issuable upon conversion thereof offered hereby may increase or
decrease.
 
                                       S-4
<PAGE>   5
 
                                                                      APPENDIX A
 
             NOTICE OF TRANSFER PURSUANT TO REGISTRATION STATEMENT
 
Marine Midland Bank, as Trustee
North American Vaccine, Inc.
c/o Marine Midland Bank
140 Broadway, 12th Floor
New York, New York 10005
Attention: Corporate Trust Services -- North American Vaccine, Inc.
 
          Re: North American Vaccine, Inc. (the "Company") 6.50% Convertible
              Subordinated Notes due May 1, 2003 (the "Notes")
 
Dear Sirs:
 
     Please be advised that                                           has
transferred $          aggregate principal amount of the above-referenced Notes,
or           number of shares of the Company's Common Stock, no par value (the
"Common Shares"), issued upon conversion of the Notes, pursuant to an effective
Registration Statement on Form S-3 (File No. 333-8851) filed by the Company.
 
     We hereby certify that the prospectus delivery requirements, if any, of the
Securities Act of 1933, as amended, have been satisfied and that the above-named
beneficial owner of the Notes or Common Shares is named as a "Selling Holder" in
the Prospectus Supplement dated April 4, 1997 or in supplements thereto, and
that the aggregate principal amount of the Notes or Common Shares transferred
are (or are included in) the Notes or Common Shares listed in such Prospectus
Supplement opposite such owner's name.
 
Dated:
 
<TABLE>
<C>                                            <S>
                                               Very truly yours,
 
                                               ----------------------------------------------
                                               (Name)
 
                                          By:
                                               ----------------------------------------------
                                               (Authorized Signature)
</TABLE>
 
                                       A-1
<PAGE>   6
 
================================================================================
 
  NO DEALER, SALESPERSON OR OTHER PERSON HAS BEEN AUTHORIZED TO GIVE ANY
INFORMATION OR TO MAKE ANY REPRESENTATIONS NOT CONTAINED IN THIS PROSPECTUS
SUPPLEMENT OR THE PROSPECTUS AND, IF GIVEN OR MADE, SUCH INFORMATION OR
REPRESENTATION MUST NOT BE RELIED UPON AS HAVING BEEN AUTHORIZED BY THE COMPANY
OR ANY OF ITS AGENTS. THIS PROSPECTUS SUPPLEMENT AND THE PROSPECTUS DO NOT
CONSTITUTE AN OFFER TO SELL OR A SOLICITATION OF AN OFFER TO BUY ANY OF THE
SECURITIES OFFERED HEREBY IN ANY JURISDICTION TO ANY PERSON TO WHOM IT IS
UNLAWFUL TO MAKE SUCH OFFER OR SOLICITATION IN SUCH JURISDICTION. NEITHER THE
DELIVERY OF THIS PROSPECTUS SUPPLEMENT OR THE PROSPECTUS NOR ANY SALE MADE
HEREUNDER OR THEREUNDER SHALL, UNDER ANY CIRCUMSTANCES, CREATE ANY IMPLICATION
THAT THE INFORMATION CONTAINED HEREIN IS CORRECT AS OF ANY TIME SUBSEQUENT TO
THE DATE HEREOF OR THAT THERE HAS BEEN NO CHANGE IN THE AFFAIRS OF THE COMPANY
SINCE SUCH DATE.
 
                               ------------------
 
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                        PAGE
                                        ----
<S>                                     <C>
           PROSPECTUS SUPPLEMENT
Selling Holders.......................  S-2
 
                 PROSPECTUS
Available Information.................    2
Incorporation of Certain Documents by
  Reference...........................    2
The Company...........................    3
Risk Factors..........................    7
Use of Proceeds.......................   12
Determination of Offering Price.......   12
Description of Notes..................   13
Certain Income Tax Considerations.....   28
Description of Capital Stock..........   34
Selling Holders.......................   35
Plan of Distribution..................   36
Legal Opinions........................   37
Independent Public Accountants........   37
Enforceability of Civil Liabilities
  Against Foreign Persons.............   37
</TABLE>
 
================================================================================


================================================================================
                                  $86,250,000
                                 NORTH AMERICAN
                                 VACCINE, INC.
                         6.50% CONVERTIBLE SUBORDINATED
 
                             NOTES DUE MAY 1, 2003
                               ------------------
 
                             PROSPECTUS SUPPLEMENT
                               ------------------
 
                              DATED APRIL 4, 1997
================================================================================


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