AMERICAN BIOGENETIC SCIENCES INC
DEF 14A, 1997-05-15
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                            SCHEDULE 14A INFORMATION
Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

Filed by the Registrant [X]

Filed by a party other than the Registrant [_]

Check the appropriate box:

[_]    Preliminary Proxy Statement
[_]    Confidential,  for  Use of the  Commission  Only  (as  permitted  by Rule
       14a-6(e)(2))
[X]    Definitive Proxy Statement
[_]    Definitive Additional Materials
[_]    Soliciting Material Pursuant to ss.240.14a-11(c) or ss.240.14a-12

                       American Biogenetic Sciences, Inc.
                ------------------------------------------------
                (Name of Registrant as Specified in Its Charter)


    ------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

[X]    No fee required

[_]    Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11

       1)     Title of each class of securities to which transaction applies:

       2)     Aggregate number of securities to which transaction applies:

       3)     Per unit price or other underlying  value of transaction  computed
              pursuant to Exchange  Act Rule 0-11 (Set forth the amount on which
              the filing fee is calculated and state how it was determined):

       4)     Proposed maximum aggregate value of transaction:

       5)     Total fee paid:

[_]    Fee paid previously with preliminary materials.

[_]    Check box if any part of the fee is offset as provided  by  Exchange  Act
       Rule  0-11(a)(2) and identify the filing for which the offsetting fee was
       paid previously.  Identify the previous filing by registration  statement
       number, or the Form or Schedule and the date of its filing.

       1)     Amount Previously Paid:

       2)     Form, Schedule or Registration Statement No.:

       3)     Filing Party:

       4)     Date Filed:


<PAGE>



                       AMERICAN BIOGENETIC SCIENCES, INC.

                                1375 AKRON STREET
                            COPIAGUE, NEW YORK 11726
                              --------------------

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                              --------------------

                                  June 18, 1997
                              --------------------

           NOTICE IS HEREBY GIVEN that the 1997 Annual  Meeting of  Stockholders
of American Biogenetic  Sciences,  Inc., a Delaware corporation (the "Company"),
will  be  held  at  Boston   University,   595  Commonwealth   Avenue,   Boston,
Massachusetts,  on  Wednesday,  June 18,  1997 at 4:00  p.m.,  Eastern  Daylight
Savings Time. The following matters are to be presented for consideration at the
meeting:

                      1. The election of seven directors to serve until the next
           annual meeting of stockholders and until their respective  successors
           are elected and qualified;

                      2. A proposal to ratify the  selection of Arthur  Andersen
           LLP as  the  Company's  independent  auditors  for  the  year  ending
           December 31, 1997; and

                      3. The  transaction of such other business as may properly
           come before the meeting or any adjournments or postponements thereof.

           The close of  business on April 21, 1997 has been fixed as the record
date for the  determination  of stockholders  entitled to notice of, and to vote
at, the meeting and any  adjournments or postponements  thereof.  A list of such
stockholders  will be open for  examination by any  stockholder  for any purpose
germane to the meeting, during ordinary business hours, for a period of at least
10 days prior to the meeting at the Boston  offices of the  Company,  801 Albany
Street, Boston, Massachusetts.

                                       By Order of the Board of Directors,

                                               Timothy J. Roach
                                                  Secretary

May 15, 1997

WHETHER OR NOT YOU EXPECT TO ATTEND THE MEETING,  PLEASE COMPLETE, DATE AND SIGN
THE  ENCLOSED  PROXY AND MAIL IT PROMPTLY IN THE  ENCLOSED  ENVELOPE IN ORDER TO
ASSURE  REPRESENTATION  OF YOUR  SHARES.  NO  POSTAGE IS NEEDED IF MAILED IN THE
UNITED STATES.



<PAGE>



                       AMERICAN BIOGENETIC SCIENCES, INC.

                                1375 AKRON STREET
                            COPIAGUE, NEW YORK 11726

                              --------------------

                                 PROXY STATEMENT
                              --------------------

           This Proxy  Statement  is  furnished to the holders of Class A Common
Stock  ("Class A Common  Stock") and to the sole holder of Class B Common  Stock
("Class B Common Stock") of American Biogenetic  Sciences,  Inc. (the "Company")
in connection with the  solicitation by the Board of Directors of the Company of
proxies in the  accompanying  form ("Proxy" or "Proxies") to be used at the 1997
Annual  Meeting of  Stockholders  of the Company (the  "Meeting")  to be held on
Wednesday, June 18, 1997, at 4:00 p.m., Eastern Daylight Savings Time, at Boston
University,  595  Commonwealth  Avenue,  Boston,   Massachusetts,   and  at  any
adjournments  and  postponements  thereof,  for the  purposes  set  forth in the
accompanying  Notice of  Annual  Meeting.  It is  anticipated  that  this  Proxy
Statement  and the Proxies  will be mailed to  stockholders  on or about May 15,
1997.  The cost of  preparing,  assembling  and  mailing  the  Notice  of Annual
Meeting,  this Proxy  Statement  and Proxies is to be borne by the Company.  The
Company will also reimburse  brokers who are holders of record of Class A Common
Stock for their expenses in forwarding Proxies and Proxy soliciting materials to
the  beneficial  owners of such  shares.  In  addition  to the use of the mails,
Proxies may be solicited without extra  compensation by directors,  officers and
employees  of  the  Company  by  telephone,   telecopy,  telegraph  or  personal
interview.  Proxies properly  executed and received in time for the Meeting will
be voted. A stockholder who signs and returns a Proxy has the power to revoke it
at any time before it is exercised by giving written notice of revocation to the
Company,  Attention:  Secretary,  by a duly executed  proxy of later date, or by
voting in person at the Meeting.

           The close of  business on April 21, 1997 has been fixed as the record
date for the  determination  of stockholders  entitled to notice of, and to vote
at, the  Meeting.  There were  outstanding,  as of the close of business on that
date,  17,962,995 shares of Class A Common Stock and 1,475,500 shares of Class B
Common  Stock.  A majority  of the total of such  outstanding  shares of Class A
Common Stock and Class B Common Stock,  represented in person or by Proxy at the
Meeting,  is required to constitute a quorum for the  transaction of business at
the  Meeting.  Holders  of Class A  Common  Stock  have one vote for each  share
thereof  held of record and the holder of Class B Common Stock has ten votes for
each share  thereof held of record.  The Class A Common Stock and Class B Common
Stock will vote as one class on all matters  proposed  herein to be submitted to
stockholders  at the Meeting.  Proxies  submitted  which contain  abstentions or
broker  nonvotes  will be deemed  present  at the  Meeting  in  determining  the
presence of a quorum.  Shares subject to abstentions  with respect to any matter
are  considered  shares  entitled  to, and voted,  with  respect to that matter.
Shares subject to broker  nonvotes with respect to any matter are not considered
as shares entitled to vote with respect to that matter.  Therefore,  abstentions
will in effect be deemed  negative votes on each proposal,  but broker  nonvotes
will  not  affect  the  results  of any of the  matters  proposed  herein  to be
submitted to stockholders at the Meeting.

           Unless  otherwise  specified,  all Proxies received will be voted for
the  election of all nominees  named herein to serve as directors  and to ratify
the selection of Arthur Andersen LLP as the Company's independent auditors.  The
Board of Directors  does not intend to bring before the Meeting any matter other
than those  specifically  described above and knows of no matters other than the
foregoing  to come  before the  Meeting.  If any other  matters or motions  come
before the Meeting, it is the intention of the persons named in the accompanying
Proxy to vote such Proxy in  accordance  with their  judgment on such matters or
motions, including any matters dealing with the conduct of the Meeting.




<PAGE>




                          SECURITY HOLDINGS OF CERTAIN
                      STOCKHOLDERS, MANAGEMENT AND NOMINEES

           The  following  table sets forth  information  at April 21, 1997 with
respect to the  beneficial  ownership of Class A Common Stock and Class B Common
Stock by (i) each person known by the Company to  beneficially  own more than 5%
of the  outstanding  shares of Class A Common Stock and/or Class B Common Stock,
(ii) each  director of the Company (each of whom is expected to be a nominee for
election as director at the Meeting),  (iii) each executive officer named in the
Summary Compensation Table under the caption "Executive  Compensation" below and
(iv) all executive  officers and directors of the Company as a group. Each share
of Class A Common  Stock is  entitled  to one vote per share while each share of
Class B Common Stock is entitled to ten votes per share. The Company understands
that,  except  as  noted  below,  each  beneficial  owner  has sole  voting  and
investment power with respect to all shares attributable to such owner.

<TABLE>
<CAPTION>
                               Class A Common Stock(1)      Class B Common Stock
                                                Percent                   Percent
Beneficial Owner              No. Shares        of Class    No. Shares    of Class
- -----------------            ------------       --------    ----------    --------
<S>                           <C>               <C>          <C>            <C> 
Alfred J. Roach (2)           3,284,250(2)      15.9%        1,475,500      100%

Paul E. Gargan                  191,000(3)       1.1%           ---         ---

Ellena M. Byrne                 185,000(3)(4)    1.0%           ---         ---

Timothy J. Roach                570,000(3)       3.1%           ---         ---

Gustav V. R. Born                 5,000(3)           *          ---         ---

Joseph C. Hogan                  40,000(3)           *          ---         ---

William G. Sharwell              45,000(3)           *          ---         ---

All executive officers
 and directors as a group
 (9 persons, including
  the foregoing)              4,516,750(5)      20.8%        1,475,500      100%
</TABLE>
- ----------------------------

(1)   Asterisk  indicates less than one percent.  Shares of Class A Common Stock
      subject to issuance upon the conversion of Class B Common Stock into Class
      A Common Stock and upon the exercise of options that were  exercisable on,
      or become  exercisable within 60 days after, April 21, 1997 are considered
      owned by the holder thereof and  outstanding for purposes of computing the
      percentage of outstanding Class A Common Stock that would be owned by such
      person,  but (except for the  computation  of beneficial  ownership by all
      executive   officers  and  directors  as  a  group)  are  not   considered
      outstanding for purposes of computing the percentage of outstanding  Class
      A Common Stock owned by any other person.

(2)   The address of Mr.  Roach is Route 2 - Kennedy  Avenue,  Guaynabo,  Puerto
      Rico  00657.  Beneficial  ownership  of  Class  A  Common  Stock  includes
      1,475,000  shares of Class A Common Stock  issuable upon the conversion of
      the same  number of  shares  of Class B Common  Stock on a share for share
      basis and 1,160,000  shares of Class A Common Stock subject to outstanding
      options.

                                              (Footnotes continued on next page)


                                       -2-

<PAGE>



(3)   Includes shares of Class A Common Stock subject to options as follows: Dr.
      Paul E. Gargan,  171,000  (including  7,000 subject to options held by his
      wife);  Ellena M. Byrne,  150,000 (including 2,500 subject to options held
      by her  husband);  Timothy J. Roach,  570,000;  Gustav V.R.  Born,  5,000;
      Joseph C. Hogan, 30,000; and William G. Sharwell, 35,000.

(4)   Includes  10,000  shares owned by Ms.  Byrne's son. The inclusion of these
      amounts  should not be  construed  as an  admission  that Ms. Byrne is the
      beneficial owner of these shares.

(5)   Includes  1,475,500  shares  of Class A  Common  Stock  issuable  upon the
      conversion  of the same  number  of  shares  of Class B Common  Stock  and
      2,298,500 shares of Class A Common Stock subject to outstanding options.


                        PROPOSAL 1. ELECTION OF DIRECTORS

           The Company's By-Laws provide that the number of members of the Board
of Directors shall be not less than three or more than nine, the exact number to
be  fixed by  resolution  of the  Board of  Directors.  The  Board of  Directors
presently  consists of seven  members.  Each of the nominees,  other than Gustav
V.R. Born (who was elected as a director by the Board in January 1997), has been
previously elected by stockholders of the Company.

           Unless  authority to do so is withheld,  Proxies will be voted at the
Meeting  for the  election  of each of the  nominees  named  below  to  serve as
directors of the Company until the next annual meeting of stockholders and until
their respective successors are elected and qualified.  In the event that any of
the nominees  should become  unavailable or unable to serve for any reason,  the
holders  of  Proxies  have  discretionary  authority  to  vote  for  one or more
alternate  nominees  designated by the Board of Directors.  The Company believes
that all of the nominees are available to serve as directors.

BACKGROUND OF NOMINEES

           Alfred J. Roach,  81, has been  Chairman of the Board of Directors of
the Company since its  organization  in September  1983 and, from September 1983
until  October  1988,  also served as President  of the  Company.  Mr. Roach has
served as  Chairman  of the  Board  and/or  President  of TII  Industries,  Inc.
("TII"), a corporation engaged in manufacturing and marketing telecommunications
products,  and its  predecessor  since its founding in 1964. Mr. Roach devotes a
majority of his time to the business of the Company.

           Paul E.  Gargan,  Ph.D.,  40,  has  served  the  Company  in  various
capacities since 1984. He has been President and a director of the Company since
January 1994 and Chief  Scientific  Officer  since June 1996 and was Senior Vice
President - Director of Research and  Development of the Company from March 1993
until  January 1994.  From November 1991 until March 1993,  Dr. Gargan served as
Vice  President  -  Cardiovascular  Products  Development  and,  from 1984 until
November  1991,  Dr.  Gargan  served as  Associate  Director  of  Cardiovascular
Research.

           Ellena M. Byrne, 46, has been Executive Vice President and a director
of the Company  since March 1995.  From January 1986 until  December  1991,  Ms.
Byrne served as Vice  President-Administration of the Company and, from December
1991 until March 1995, Ms. Byrne served in various  capacities with the Company,
including Director of Operations for Europe and Asia.

           Timothy J. Roach, 50, has been Treasurer, Secretary and a director of
the Company since  September  1983. He has also been  affiliated  with TII since
1974,  serving as its President since July 1980,  Chief Operating  Officer since
May 1987, Vice Chairman of the Board since October 1993, Chief Executive Officer
since January 1995 and a director  since  January  1978.  Mr. Roach devotes such
time as is necessary  to the business of the Company to discharge  his duties as
Treasurer,  Secretary  and a director.  Timothy J. Roach is the son of Alfred J.
Roach.


                                       -3-

<PAGE>





           Gustav  Victor Rudolf Born,  M.D.,  D.Phil.,  F.R.S.,  75, has been a
director of the  Company  since  January  1997.  Since  1988,  Dr. Born has been
Research Director of The William Harvey Research Institute at St.  Bartholomew's
Hospital Medical College, London, England and Emeritus Professor of Pharmacology
in the University of London.  Among Dr. Born's  distinctions,  appointments  and
activities are: Fellowship and Royal Medal of the Royal Society;  and Foundation
President of the British Society for Thrombosis and Haemostasis.

           Joseph C. Hogan,  Ph.D., 74, has been a director of the Company since
December  1983.  Dr. Hogan served as Dean of the College of  Engineering  of the
University of Notre Dame from 1967 to 1981, following which he performed various
services  for the  University  of Notre Dame until 1985,  where he remains  Dean
Emeritus.  From 1985 until his  retirement  in 1987,  Dr.  Hogan was Director of
Engineering  Research and Resource  Development  at Georgia Tech. Dr. Hogan is a
director of TII.

           William G. Sharwell,  D.C.S.,  76, has been a director of the Company
since October 1986.  Dr.  Sharwell was President of Pace  University in New York
from 1984 until his retirement in 1990. He was Senior Vice President of American
Telephone & Telegraph  Company  between 1976 and 1984, and previously  served as
Executive  Vice  President of  Operations  of New York  Telephone  Company.  Dr.
Sharwell serves as an independent general partner of Equitable Capital Partners,
L.P.  and  Equitable  Capital  Partners  (Retirement  Fund),  L.P.,   registered
investment companies under the Investment Company Act of 1940. He also serves on
the Board of Directors of TII and US Life Corporation.

MEETINGS OF THE BOARD OF DIRECTORS

           During the year ended  December 31, 1996, the Board of Directors held
two meetings and acted by unanimous  written consent on six occasions  following
informal discussions. During 1996, each director attended all of the meetings of
the Board of Directors and committees of the Board on which such director served
that were held during the period such person served as a director.

COMMITTEES OF THE BOARD OF DIRECTORS

           The Board of Directors has an Audit and Compensation  Committee,  but
does not have a nominating committee.

           The Audit  Committee,  which consists of Messrs.  Hogan and Sharwell,
held two meetings during 1996. It is authorized to examine and consider  matters
related  to the audit of the  Company's  accounts,  the  financial  affairs  and
accounts of the Company,  the scope of the independent  auditors' engagement and
their  compensation,  the effect on the  Company's  financial  statements of any
proposed changes in generally accepted accounting principles,  disagreements, if
any, between the Company's  independent auditors and management,  and matters of
concern to the  independent  auditors  resulting  from the audit,  including the
results of the independent  auditors'  review of internal  accounting  controls.
This committee is also authorized to nominate independent  auditors,  subject to
approval by the Board of Directors. The Audit Committee held two meetings during
1996.

           The Compensation Committee is authorized to consider and recommend to
the Board of Directors the salaries, bonuses and other compensation arrangements
with respect to the executive  officers of the Company.  This  Committee is also
empowered to grant all options under, and administer, the Company's stock option
plans. The Compensation  Committee is further  empowered to examine,  administer
and make  recommendations  to the full  Board  with  respect  to other  employee
benefit  plans and  arrangements  of the  Company.  The  Compensation  Committee
presently  consists  of Messrs.  Joseph C. Hogan and  William G.  Sharwell.  The
Compensation  Committee  held one meeting  during  1996,  and acted by unanimous
written consent on eight occasions following informal discussions.




                                       -4-

<PAGE>



REMUNERATION OF DIRECTORS

           Directors  receive no  compensation  for  service on the Board.  Each
director serving on the Audit Committee  receives a fee of $600 for each meeting
of the committee attended by that director in person and not telephonically. All
directors are reimbursed  for travel  expenses  incurred in attending  Board and
committee meetings.

           The Company's 1993 Non-Employee  Director Stock Option Plan, approved
by stockholders at the Company's 1993 Annual Meeting of  Stockholders,  provides
for the  automatic  grant of an option to purchase  10,000 shares of the Class A
Common Stock to each non-employee director holding office immediately after each
annual meeting of  stockholders.  The exercise price for each option is equal to
the fair  market  value of the Class A Common  Stock on the date of  grant.  All
options have a term of five years and are exercisable, on a cumulative basis, at
the rate of one  quarter of the  number of shares  subject to the option in each
year commencing one year after the date of the grant.

           See  "Executive   Compensation"   for   information   concerning  the
compensation of Mr. Alfred J. Roach and Dr. Paul E. Gargan for their services as
executive officers of the Company.  The Company is also a party to an employment
agreement dated October 1, 1996 with Ms. Ellena M. Byrne,  pursuant to which Ms.
Byrne is serving as Executive  Vice  President of the  Company.  The  Employment
Agreement  provides  for  a  term  extending,   subject  to  certain  terms  and
conditions,  until  September 30, 2001 and an annual salary of U.S.  $18,200 and
(pound)50,000  Irish Pounds (U.S. $78,800 at March 31, 1997). Dr. Born serves as
a consultant  to the Company for which he receives  compensation  at the rate of
$12,000 per annum.

REQUIRED VOTE

           A plurality  of the votes cast at the Meeting by the holders of Class
A Common Stock and Class B Common Stock voting together as one class, with Class
A Common  Stock  having one vote per share and Class B Common  Stock  having ten
votes per share,  will be required for the election of  directors.  The Board of
Directors recommends that stockholders vote FOR each of Alfred J. Roach, Paul E.
Gargan, Ellena M. Byrne, Timothy J. Roach, Gustav V.R. Born, Joseph C. Hogan and
William G. Sharwell to serve as directors of the Company.


                               EXECUTIVE OFFICERS

           The only executive officers of the Company,  in addition to Alfred J.
Roach, Paul E. Gargan,  Timothy J. Roach and Ellena M. Byrne (whose  backgrounds
are described under the caption "Election of Directors - Background of Nominees"
above), are:

           Stephen H. Ip, Ph.D., 50, has been Executive Vice President and Chief
Operating  Officer of the  Company  since  January  1997.  Prior to joining  the
Company, Dr. Ip served as Vice President,  Corporate and Business Development at
Paracelsian,  Inc.,  a public  company  engaged  in  clinical  and  pre-clinical
development of drugs and supplements for the treatment of AIDS and cancer,  from
1996.  From 1990  through  1995,  Dr. Ip served as  President,  Chief  Operating
Officer and director of CytoMed,  Inc., a  biopharmaceutical  company engaged in
the  research  and  development  of  synthetic  chemical  drugs and  recombinant
proteins for the treatment of acute and chronic diseases. From 1984 through 1989
he was Vice President and a scientific  co-founder of T Cell  Sciences,  Inc., a
biotechnology company.



                                       -5-

<PAGE>



           Joseph P. Laurino, Ph.D., 39, has been Senior Vice President-Research
and  Development  of the  Company  since  February  1997.  Prior to joining  the
Company,  Dr.  Laurino  served as Director of Clinical  Chemistry  and Assistant
Professor of Pathology in the Department of Pathology and Laboratory Medicine at
Memorial Hospital of Rhode Island, Brown University, from 1990 to February 1996.
Dr.  Laurino was also Senior  Scientist for Roche  Diagnostic  Systems,  Inc., a
multi-national  diagnostic  company,  from  1988 to  1990,  and a  Research  and
Development   Scientist  at  Technicon   Instruments   Corporation   (now  Bayer
Corporation), a multi-national diagnostic company from 1987 to 1988.

           James H.  McLinden,  Ph.D.,  46, has been Vice  President - Molecular
Biology of the Company since November 1991. Prior thereto (and since joining the
Company in January 1987),  Dr. McLinden served as Director of Molecular  Biology
of the Company.

           Josef  C.  Schoell,  47,  joined  the  Company  in  July  1992 as its
Controller and was elected Vice President-Finance and Chief Financial Officer of
the Company in July 1995. For more than four years prior to joining the Company,
Mr.  Schoell  served  as  a  private  consultant  specializing  in  computerized
accounting  systems and networks.  Prior thereto,  Mr. Schoell served in various
capacities, most recently Assistant Controller, with J.P. Stevens & Co., Inc., a
textile  manufacturing  company. Mr. Schoell is a Certified Public Accountant in
the State of New York.


                             EXECUTIVE COMPENSATION

SUMMARY COMPENSATION TABLE

           The following table sets forth information  concerning the annual and
long-term  compensation  of  the  Company's  chief  executive  officer  and  its
President,  the  only  executive  officers  of the  Company  whose  annual  cash
compensation for 1996 exceeded  $100,000,  for services in all capacities to the
Company during 1994, 1995 and 1996:

                                          ANNUAL           LONG-TERM
                                       COMPENSATION      COMPENSATION
     NAME AND                        ----------------    ------------
PRINCIPAL POSITION                   YEAR      SALARY       OPTIONS
- ------------------                   ----      ------       -------

Alfred J. Roach, Chairman            1996     $250,000          --
  of the Board and Chief             1995     $250,000      135,000
  Executive Officer                  1994     $250,000          --

Paul E. Gargan, President            1996     $162,000          --
                                     1995     $150,000       31,500
                                     1994     $148,000       50,000




                                       -6-

<PAGE>



OPTION EXERCISES IN LAST FISCAL YEAR AND YEAR-END VALUES

           No  options  were  granted  during  1996 to either  of the  executive
officers named in the Summary  Compensation  Table. The following table contains
information  concerning  options exercised during 1996, and the number of shares
of Class A Common  Stock  underlying  unexercised  options  held at December 31,
1996, by the executive officers named in the Summary Compensation Table.

<TABLE>
<CAPTION>
                                                                                VALUE OF
                                                          NUMBER OF             UNEXERCISED
                                                          UNEXERCISED           IN-THE-MONEY
                                                          OPTIONS HELD AT       OPTIONS HELD AT
                                                          FISCAL YEAR-END(#)    FISCAL YEAR-END($)
                    SHARES ACQUIRED    VALUE              (EXERCISABLE/         (EXERCISABLE/
         NAME       ON EXERCISE (#)    REALIZED($)(1)     UNEXERCISABLE)        UNEXERCISABLE)(2)
         ----       ---------------    --------------     --------------        -----------------
<S>                     <C>              <C>              <C>       <C>         <C>       <C>    
 Alfred J. Roach        300,000          $127,500         1,126,250/33,750      $ 216,422/$72,141

 Paul E. Gargan (3)         --               --            143,625/32,875       $ 85,570/$18,211
</TABLE>

- --------------
(1)   The  closing  price of the  Company's  Class A Common  Stock on The Nasdaq
      Stock Market's  National Market on the date of exercise of the option less
      the exercise price of the option.

(2)   The closing price of the  Company's  Class A Common Stock The Nasdaq Stock
      Market's  National  Market on December 31, 1996 less the exercise price of
      each option.

(3)   Excludes options held by Dr. Gargan's wife.

EMPLOYMENT AGREEMENTs

           The Company is a party to an employment  agreement dated May 10, 1996
with Dr. Paul E. Gargan,  President of the  Company,  which  provides for a term
extending,  subject to certain terms and  conditions,  until June 30, 1998.  Dr.
Gargan's annual salary was increased from $150,000 to $175,000 effective July 1,
1996

REPORT OF COMPENSATION COMMITTEE CONCERNING EXECUTIVE COMPENSATION

           The Compensation  Committee of the Board of Directors,  consisting of
Messrs.  Joseph C. Hogan and  William  G.  Sharwell,  "non-employee"  directors,
within the meaning of Rule 16b-3  promulgated  by the  Securities  and  Exchange
Commission under the Securities  Exchange Act of 1934, and "outside  directors",
within the meaning of Section  162(m) of the Internal  Revenue Code of 1986,  as
amended ("Section 162(m)"), is authorized to consider and recommend to the Board
of Directors salaries, bonuses and other compensation arrangements for executive
officers and to grant all options under, and administer,  the Company's employee
stock option plans.

           The  Compensation   Committee   believes  that  the  Company,   as  a
development stage company,  should create  compensation  packages to attract and
retain  executives  who can  bring the  experience  and  skills  to the  Company
necessary for the development of the Company and its products. To date, this has
been accomplished by utilizing salary as the base compensation and stock options
to promote long-term incentives. As the Company grows, other forms of annual and
long-term  compensation  arrangements  may be developed  to provide  appropriate
incentives and to reward specific accomplishments.



                                       -7-

<PAGE>



           In determining base salaries,  the Compensation  Committee  examines,
among other factors, the executive's  performance,  degree of responsibility and
experience,  as well as general employment  conditions and economic factors.  No
specific weights are assigned to any of the factors employed by the Compensation
Committee.  In 1996, the salaries of certain executive  officers were increased,
using subjective standards, to recognize their performance.

           The Compensation Committee also makes use of stock options to provide
long-term incentive  compensation to many of the Company's employees,  including
executive officers,  enabling them to benefit,  along with all stockholders,  if
the market  price for Class A Common  Stock rises.  The  Compensation  Committee
believes that the use of stock  options ties employee  interests to those of the
Company's  stockholders  through stock ownership and potential stock  ownership,
while also providing the Company with a means of compensating  employees using a
method which enables the Company to conserve its available  cash for  operations
and  product  development.  To assure  the  long-term  nature of the  incentive,
options  granted have  generally  not become  exercisable  during the first year
after grant and thereafter have become  exercisable over a period of two to four
years. Decisions of the Compensation Committee as to option grants are based, in
large  measure,  upon a  review  of such  factors  as the  executive's  level of
responsibility, other compensation, accomplishments and goals, and when the last
option was granted to such executive, as well as recommendations and evaluations
of the executive's  performance and prospective  contributions  by the Company's
Chief  Executive.  Determinations  have been made  subjectively  without  giving
weight to specific factors.

           Chief Executive Officer Compensation.  The salary of Alfred J. Roach,
the Company's Chief Executive  Officer has remained  unchanged for the past four
years, although he was granted options to purchase shares of the Company's Class
A Common  Stock  during  1995  under the  Company's  1986 Stock  Option  Plan in
recognition of his efforts on behalf of the Company.  No options were granted to
Mr. Roach in 1996.

           Certain Tax  Legislation.  Section 162(m)  precludes a public company
from taking a federal income tax deduction for annual  compensation in excess of
$1,000,000  paid to its chief  executive  officer  or any of its four other most
highly compensated executive officers.  Certain "performance based compensation"
is excluded from the deduction limitation.  Any compensation  resulting from the
exercise  of stock  options  granted  by the  Company  should  be  eligible  for
exclusion. Any compensation resulting from the exercise of stock options granted
by the Company  should be eligible for  exclusion  since all options were either
granted prior to the adoption of Section  162(m) or under a plan approved by the
Company's  stockholders  which  was  designed  to  conform  to  regulations  for
determining  whether options are deemed  "performance  based  compensation." The
Committee  believes that the  limitations on  compensation  deductibility  under
Section 162(m) will have no effect on the Company in the foreseeable future, and
intends to take such action as may be necessary, including obtaining stockholder
approval  where  required,  in order for  compensation  not to be subject to the
limitation on deductibility imposed by Section 162(m) of the Code.

Respectfully submitted,


Joseph C. Hogan
William G. Sharwell




                                       -8-

<PAGE>



PERFORMANCE GRAPH

           The following graph compares the cumulative return to stockholders of
Class A Common  Stock  from  January  1,  1992  (the  first  point  shown in the
following  graph) through December 31, 1996 with the Nasdaq Market Index and the
Dow Jones  Industry  Group BTC -  Biotechnology  Index for the same period.  The
comparison  assumes  $100 was  invested on  December  31, 1991 in Class A Common
Stock  and in  each  of the  comparison  groups,  and  assumes  reinvestment  of
dividends (the Company paid no dividends during the periods):




                                  [GRAPH HERE]



At December 31,                         1991   1992   1993   1994    1995   1996
- --------------------------------------------------------------------------------
American Biogenetic Sciences             100     71     63     19      35     52
Peer Group Index                         100     84     79     71     121    125
NASDAQ Market Index                      100    101    121    127     165    205
- --------------------------------------------------------------------------------


SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

           Section 16(a) of the  Securities  Exchange Act requires the Company's
executive officers and directors, and persons who beneficially own more than 10%
of the Company's Class A Common Stock, to file initial reports of ownership, and
reports of changes of ownership,  of the Company's  equity  securities  with the
Securities  and Exchange  Commission  and furnish copies of those reports to the
Company.  Based  solely on a review of copies of the  reports  furnished  to the
Company, or written  representation  that no reports were required,  the Company
believes  that all reports  required to be filed by such persons with respect to
the Company's  year ended  December 31, 1996 were timely filed,  except that Ms.
Byrne failed to timely file one report  covering the receipt of a gift of Common
Stock by her minor child.

                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

           On January 17, 1997, Mr. Alfred J. Roach purchased  100,000 shares of
the  Company's  Class B Common  Stock for  $343,750,  or $3.4375 per share,  the
closing  bid  price  of the  Company's  Class A Common  Stock  (into  which  the
Company's Class B Common Stock is convertible on a share-for-share basis) on The
Nasdaq Stock Market's National Market on that date.



                                       -9-

<PAGE>




          PROPOSAL 2. RATIFICATION OF SELECTION OF INDEPENDENT AUDITORS

           The Board of Directors  has selected the firm of Arthur  Andersen LLP
as the  independent  auditors of the Company  for the year ending  December  31,
1997. Arthur Andersen LLP has acted for the Company in such capacity since 1987.
The Board proposes that the stockholders ratify such selection at the Meeting.

           Representatives  of Arthur Andersen LLP are expected to be present at
the Meeting and will be afforded an  opportunity  to make a statement if they so
desire and to respond to appropriate questions.

REQUIRED VOTE

           The  affirmative  vote of a majority  of the shares of Class A Common
Stock and Class B Common Stock  present,  in person or by proxy,  at the Meeting
and entitled to vote on this proposal,  voting together as one class, with Class
A Common  Stock  having one vote per share and Class B Common  Stock  having ten
votes per share, will be required to adopt this proposal. The Board of Directors
recommends that stockholders vote FOR approval of this proposal.


                                  MISCELLANEOUS

STOCKHOLDER PROPOSALS

           From time to time  stockholders  may present  proposals  which may be
proper  subjects for inclusion in the proxy statement and form of proxy relating
to that meeting. In order to be considered,  such proposals must be submitted in
writing on a timely basis.  Stockholder proposals intended to be included in the
Company's  proxy  statement  and form of proxy  relating to the  Company's  next
Annual Meeting of Stockholders must be received at 1375 Akron Street,  Copiague,
New  York  11726,  by  January  15,  1998.  Any such  proposals,  as well as any
questions relating thereto, should be directed to the Secretary of the Company.

ANNUAL REPORT ON FORM 10-K

           A copy of the Company's Annual Report on Form 10-K for the year ended
December  31,  1996,  which has been  filed  with the  Securities  and  Exchange
Commission,  is  also  available,   without  charge,  to  stockholders  who  are
interested in more detailed  information about the Company.  Requests for a copy
of that report should be addressed to Timothy J. Roach, Treasurer, at 1375 Akron
Street, Copiague, New York 11726.

                                             By Order of the Board of Directors,


                                                     Timothy J. Roach
                                                        Secretary

May 15, 1997


                                      -10-

<PAGE>



                       AMERICAN BIOGENETIC SCIENCES, INC.
            PROXY FOR ANNUAL MEETING OF STOCKHOLDERS - JUNE 18, 1997

           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

           The  undersigned  hereby  appoints,  as proxies for the  undersigned,
JAMES R. GROVER, JR., TIMOTHY J. ROACH and LEONARD W. SUROFF, or any one or more
of them,  with full power of  substitution,  to vote all  shares of the  capital
stock  of  American  Biogenetic   Sciences,   Inc.  (the  "Company")  which  the
undersigned  is entitled to vote at the Annual  Meeting of  Stockholders  of the
Company to be held on Wednesday,  June 18, 1997, at 4:00 P.M.,  Eastern Daylight
Savings  Time,  at  Boston   University,   595  Commonwealth   Avenue,   Boston,
Massachusetts,  and at any  adjournments or  postponements  thereof,  receipt of
Notice of which  meeting  and the Proxy  Statement  accompanying  the same being
hereby acknowledged by the undersigned, upon the matters described in the Notice
of Meeting and Proxy Statement and upon such other business as may properly come
before  the  meeting  and any  adjournments  or  postponements  thereof,  hereby
revoking any proxies heretofore given.

           EACH PROPERLY  EXECUTED  PROXY WILL BE VOTED IN  ACCORDANCE  WITH THE
SPECIFICATIONS  MADE BELOW AND ON THE REVERSE SIDE HEREOF.  IF NO SPECIFICATIONS
ARE MADE,  THE  PROXIES  WILL BE VOTED  FOR EACH  LISTED  NOMINEE  TO SERVE AS A
DIRECTOR AND FOR PROPOSAL 2.

           A VOTE FOR EACH  NOMINEE  AND FOR  PROPOSAL 2 IS  RECOMMENDED  BY THE
BOARD OF DIRECTORS.


1.    Election of Directors (check one box only)




[_]   FOR EACH NOMINEE LISTED BELOW                [_]    WITHHOLD AUTHORITY
      (except as marked to the contrary below):           to vote for all 
                                                          nominees listed below

            ALFRED J. ROACH, PAUL E. GARGAN,  ELLENA M. BRYNE, TIMOTHY J. ROACH,
            GUSTAV V. R. BORN, JOSEPH C. HOGAN and WILLIAM G. SHARWELL

(Instruction:  To  withhold  authority  to vote  for any  nominee,  circle  that
nominee's name in the above list)

                                    (continued and to be signed on reverse side)






<PAGE>



2.    To ratify the selection of Arthur Andersen LLP as independent auditors for
      the Company.


                                             FOR          AGAINST        ABSTAIN
                                             [_]            [_]             [_]


                                             Dated:_______________________, 1997


                                             ___________________________________
                                                   (SIGNATURE OF STOCKHOLDER)


                                             ___________________________________
                                                   (SIGNATURE OF STOCKHOLDER)


                                             NOTE:  PLEASE  SIGN  YOUR  NAME  OR
                                             NAMES  EXACTLY AS SET FORTH HEREON.
                                             FOR  JOINTLY  OWNED  SHARES,   EACH
                                             OWNER  SHOULD  SIGN.  IF SIGNING AS
                                             ATTORNEY, EXECUTOR,  ADMINISTRATOR,
                                             TRUSTEE   OR    GUARDIAN,    PLEASE
                                             INDICATE  THE CAPACITY IN WHICH YOU
                                             ARE  ACTING.  PROXIES  EXECUTED  BY
                                             CORPORATIONS  SHOULD BE SIGNED BY A
                                             DULY AUTHORIZED  OFFICER AND SHOULD
                                             BEAR THE CORPORATE SEAL.

              PLEASE DATE AND SIGN THIS PROXY AND MAIL IT PROMPTLY
           IN THE ENCLOSED ENVELOPE. NO POSTAGE IS REQUIRED IF MAILED
                              IN THE UNITED STATES.




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