AMERICAN BIOGENETIC SCIENCES INC
SC 13G/A, 1997-02-24
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                               (Amendment No. 5)*



                          AMERICAN BIOGENETIC SCIENCES, INC.
                -------------------------------------------------
                                (Name of Issuer)

                     CLASS A COMMON STOCK, $.001 par value per share
                -------------------------------------------------
                         (Title of Class of Securities)

                                   024611 10 5
                       -----------------------------------
                                 (CUSIP Number)

Check the following box if a fee is being paid with the statement [_]. (A fee is
not required only if the reporting person:  (1) has a previous statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7.)

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for  any  subsequent   amendment   containing   information  which  would  alter
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).



<PAGE>

                                       13G
- ----------------------                                         -----------------
CUSIP No.  024611 10 5                                         Page 2 of 5 Pages
- ----------------------                                         -----------------



1        NAME OF REPORTING PERSON
         S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON

         ALFRED J. ROACH
         
- --------------------------------------------------------------------------------
2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*              (a) [_]
                                                                        (b) [_]


- --------------------------------------------------------------------------------
3        SEC USE ONLY


- --------------------------------------------------------------------------------
4        CITIZENSHIP OR PLACE OF ORGANIZATION

         United States of America
- --------------------------------------------------------------------------------
                                 5       SOLE VOTING POWER
       
                                         3,050,500

                              --------------------------------------------------
 NUMBER OF                       6       SHARED VOTING POWER
   SHARES   
BENEFICIALLY                             -0-
  OWNED BY                    
    EACH                      --------------------------------------------------
 REPORTING                       7       SOLE DISPOSITIVE POWER
   PERSON   
    WITH                                 3,050,500

                              --------------------------------------------------
                                 8       SHARED DISPOSITIVE POWER

                                         -0-
- --------------------------------------------------------------------------------
9        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

         3,050,500

- --------------------------------------------------------------------------------
10       CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES*
                                                                           [_]


- --------------------------------------------------------------------------------
11       PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

         16.2%

- --------------------------------------------------------------------------------
12       TYPE OF REPORTING PERSON*

         IN

- --------------------------------------------------------------------------------
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!



<PAGE>

- ----------------------                                         -----------------
CUSIP No.  024611 10 5                                         Page 3 of 5 Pages
- ----------------------                                         -----------------







Item 1(a)      Name of Issuer:

               AMERICAN BIOGENETIC SCIENCES, INC.

Item 1(b)      Address of Issuer's Principal Executive Offices:

               1375 Akron Street
               Copiague, New York 11726

Item 2(a)      Name of Person Filing:

               Alfred J. Roach

Item 2(b)      Address of Principal Business Office or, if none, Residence:

               1375 Akron Street
               Copiague, NY 11726

Item 2(c)      Citizenship:

               United  States of America.

Item 2(d)      Title of Class of Securities:

               Common Stock, $.001 par value per share

Item 2(e)      CUSIP Number:

               024611 10 5

Item 3         Statements filed pursuant to Rule 13d-1(b) or 13d-2(b)

               Not Applicable

Item 4         Ownership of Securities:

               The following information is as at December 31, 1996:

               (a)  Amount Beneficially Owned:  3,050,500

                    Consists of (i) 548,750 shares of Class A Common Stock; (ii)
                    1,375,500  shares  of Class A  Common  Stock  issuable  upon
                    conversion  of the same  number of  shares of the  Company's
                    Class B Common  Stock,  $.001  par  value  ("Class  B Common
                    Stock"), each of which is convertible into

<PAGE>

- ----------------------                                         -----------------
CUSIP No.  024611 10 5                                         Page 4 of 5 Pages
- ----------------------                                         -----------------


                    one share of Class A Common Stock;   (iii) 1,126,250  shares
                    of Class A Common Stock which are not  outstanding but which
                    are  subject to  issuance  upon  exercise  of the portion of
                    options  which  were   exercisable   on,   or  which  become
                    exercisable  within   sixty  days  of,  December  31,  1996,
                    granted to Mr. Roach  under the Company's  Stock Option Plan
                    (the  "Options").   Each  share of  Class B Common  Stock is
                    entitled   to ten times the number of votes of each share of
                    Class  A Common Stock.

               (b)  Percent of Class:  16.2%

                    Based  on  16,270,994   shares   of  Class  A  Common  Stock
                    outstanding on December 31, 1996  and assuming conversion of
                    all shares of Class B Common Stock beneficially owned by Mr.
                    Roach and the execise of the Options.

               (c)  Number of shares to which such person has:


                     (i)    sole power to vote or to direct the vote - 3,050,500
                     (ii)   shared power to vote or to direct the vote - 0
                     (iii)  sole power to  dispose or to direct the  disposition
                            of - 3,050,500
                     (iv)   shared power to dispose or to direct the disposition
                            of - 0

Item 5.        Ownership of Five Percent or Less of a Class:

               Not applicable

Item 6.        Ownership of More than Five Percent on Behalf of Another Person:

               Not applicable

Item 7         Identification   and   Classification  of  the  Subsidiary  Which
               Acquired the Security Being  Reported  on  By  the Parent Holding
               Company:

               Not Applicable.

Item 8         Identification and Classification of Members of the Group:

               Not Applicable.



<PAGE>

- ----------------------                                         -----------------
CUSIP No.  024611 10 5                                         Page 5 of 5 Pages
- ----------------------                                         -----------------

Item 9         Notice of Dissolution of Group:

               Not Applicable.

Item 10        Certification:

               Not Applicable.




           After reasonable  inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and
correct.


Dated:  February 14, 1997

                                        /s/ Alfred J. Roach
                                     -------------------------------
                                     Alfred J. Roach


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