AMERICAN BIOGENETIC SCIENCES INC
SC 13G/A, 1998-02-10
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G


                    Under the Securities Exchange Act of 1934
                               (AMENDMENT NO. 6 )*




                       American Biogenetic Sciences, Inc.
     ---------------------------------------------------------------------
                                (Name of Issuer)

                 CLASS A COMMON STOCK, $.001 par value per share
     ---------------------------------------------------------------------
                         (Title of Class of Securities)

                                   024611 10 5
                -------------------------------------------------
                                 (CUSIP Number)


Check the following box if a fee is being paid with the statement [_]. (A fee is
not required  only if the filing  person:  (1) has a previous  statement on file
reporting  beneficial  ownership  of more  than  five  percent  of the  class of
securities  described  in Item 1;  and (2) has  filed  no  amendment  subsequent
thereto reporting  beneficial  ownership of five percent or less of such class.)
(See Rule 13d-7).

*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).


SEC 1745 (2-95)
<PAGE>



- ---------------------                                          -----------------
CUSIP NO. 024611 10 5                 13G                      PAGE 2 OF 5 PAGES
- ---------------------                                          -----------------



- --------------------------------------------------------------------------------
     1        NAME OF REPORTING PERSON
              S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON\

              Alfred J. Roach
- --------------------------------------------------------------------------------
     2        CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
                                                                        (a) [_]
                                                                        (b) [_]
- --------------------------------------------------------------------------------
     3        SEC USE ONLY


- --------------------------------------------------------------------------------
     4        CITIZENSHIP OR PLACE OF ORGANIZATION

              United States
- --------------------------------------------------------------------------------
                                 5       SOLE VOTING POWER
                              
                                          3,618,750
                              --------------------------------------------------
                                 6       SHARED VOTING POWER 
       NUMBER OF                                                         
         SHARES                              -0-                 
      BENEFICIALLY            --------------------------------------------------
        OWNED BY                 7       SOLE DISPOSITIVE POWER
          EACH    
       REPORTING                         3,618,750
         PERSON               --------------------------------------------------
          WITH                   8       SHARED DISPOSITIVE POWER
      
                                             -0-
- --------------------------------------------------------------------------------
     9        AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              3,618,750
- --------------------------------------------------------------------------------
    10        CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
              SHARES*                                                      [_]

- --------------------------------------------------------------------------------
    11        PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

              16.3%
- --------------------------------------------------------------------------------
    12        TYPE OF REPORTING PERSON*

              IN
- --------------------------------------------------------------------------------
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!


SEC 1745 (2-95)

<PAGE>


- ---------------------                                          -----------------
CUSIP NO. 024611 10 5                 13G                      PAGE 3 OF 5 PAGES
- ---------------------                                          -----------------


Item 1(a)   Name of Issuer:

            AMERICAN BIOGENETIC SCIENCES, INC.

Item 1(b)   Address of Issuer's Principal Executive Offices:

            1375 Akron Street
            Copiague, New York 11726

Item 2(a)   Name of Person Filing:

            Alfred J. Roach

Item 2(b)   Address of Principal Business Office or, if none, Residence:

            1375 Akron Street
            Copiague, NY 11726

Item 2(c)   Citizenship:

            United  States of America.

Item 2(d)   Title of Class of Securities:

            Common Stock, $.001 par value per share

Item 2(e)   CUSIP Number:

            024611 10 5

Item 3      Statements filed pursuant to Rule 13d-1(b) or 13d-2(b):

            Not Applicable

Item 4      Ownership of Securities:

            The following information is as at December 31, 1997:

            (a)  Amount Beneficially Owned:  3,618,750

            Consists  of (i)  733,250  shares  of  Class A  Common  Stock;  (ii)
            1,725,500 shares of Class A Common Stock issuable upon conversion of
            the same  number of shares of the  Company's  Class B Common  Stock,
            $.001  par  value  ("Class  B  Common  Stock"),  each  of  which  is
            convertible into

SEC 1745 (2-95)

<PAGE>


- ---------------------                                          -----------------
CUSIP NO. 024611 10 5                 13G                      PAGE 4 OF 5 PAGES
- ---------------------                                          -----------------


            one share of Class A Common Stock; (iii) 1,160,000 shares of Class A
            Common  Stock  which are not  outstanding  but which are  subject to
            issuance  upon  exercise  of  the  portion  of  options  which  were
            exercisable  on, or which become  exercisable  within sixty days of,
            December 31, 1997,  granted to Mr. Roach under the  Company's  Stock
            Option Plan (the  "Options").  Each share of Class B Common Stock is
            entitled  to ten times the  number of votes of each share of Class A
            Common Stock.

            (b)    Percent of Class: 16.3%

            Based on 19,341,617  shares of Class A Common Stock  outstanding  on
            December 31, 1997 and assuming  conversion  of all shares of Class B
            Common Stock beneficially owned by Mr. Roach and the exercise of the
            Options.

            (c)    Number of shares to which such person has:

                   (i)   sole power to vote or to direct the vote - 3,618,750
                   (ii)  shared power to vote or to direct the vote - 0
                   (iii) sole power to dispose or to direct the disposition of -
                         3,618,750
                   (iv)  shared power to dispose or to direct the disposition of
                         - 0

Item 5.     Ownership of Five Percent or Less of a Class:

            Not applicable.

Item 6.     Ownership of More than Five Percent on Behalf of Another Person:

            Not applicable.

Item 7      Identification  and  Classification of the Subsidiary Which Acquired
            the Security Being Reported on By the Parent Holding Company:

            Not Applicable.

Item 8      Identification and Classification of Members of the Group:

            Not Applicable.



SEC 1745 (2-95)

<PAGE>


- ---------------------                                          -----------------
CUSIP NO. 024611 10 5                 13G                      PAGE 5 OF 5 PAGES
- ---------------------                                          -----------------

Item 9      Notice of Dissolution of Group:

            Not Applicable.

Item 10     Certification:

            Not Applicable.


            After reasonable inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and
correct.


Dated:  February 9, 1998


                                                     /s/ Alfred J. Roach
                                                     ------------------------
                                                     Alfred J. Roach


SEC 1745 (2-95)


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