AVANIR PHARMACEUTICALS
8-K, 1999-04-01
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549


                                    FORM 8-K


                                 CURRENT REPORT
                       Pursuant to Section 13 or 15(d) of
                       The Securities Exchange Act of 1934


                         Date of Report: March 22, 1999
                        (Date of earliest event reported)


                             AVANIR PHARMACEUTICALS
             (Exact name of registrant as specified in its charter)


                                   CALIFORNIA
                 (State or other jurisdiction of incorporation)


            0-18734                                     33-0314804
   (Commission File Number)                 (IRS Employer Identification No.)


       9393 Towne Centre Drive, Suite 200, San Diego, California 92121
               (Address of principal executive offices)        (Zip code)


                                 (619) 558-0364
               (Registrants telephone number, including area code)



<PAGE>   2
Item 5.  OTHER EVENTS

        On March 22, 1999, AVANIR Pharmaceuticals (the "Company") entered into a
letter amendment (the "Letter Amendment") to the Class A Common Stock Investment
Agreement, dated as of January 22, 1999 (the "Equity Line Agreement"), which
agreement allows the Company to access potentially up to $10 million in equity
line financing over a two-year period through sales of its Class A Common Stock
to a New York City-based private investment firm (the "Investor"). The Letter
Amendment amends the Equity Line Agreement (and related Registration Rights
Agreement) to provide, among others, the following terms:

1.  The Letter Amendment adjusts certain time periods during which the Company
    can sell shares of its Class A Common Stock to the Investor under the equity
    line.

2.  Under the Equity Line Agreement, the Investor cannot own more than 4.99% of
    the total outstanding shares of the Company's Class A Common Stock at any
    one time; the Letter Amendment includes in this share calculation shares of
    Class A Common Stock acquired by any affiliate of the Investor pursuant to
    the Company's Series D Convertible Preferred Stock financing (the "Preferred
    Stock Financing").

3.  If any shares of the Company's Series D Convertible Preferred Stock are
    outstanding or if certain shares of the Company's Series D Convertible
    Preferred Stock are issuable under the Preferred Stock Financing, then the
    Company must obtain the approval of its shareholders to issue (i) all of the
    shares of Class A Common Stock under the Equity Line Agreement and (ii) all
    of the securities in connection with the Preferred Stock Financing.

4.  The Equity Line Agreement automatically terminates upon the earlier of (i)
    when the Investor has purchased an aggregate of $10,000,000 in shares of
    Class A Common Stock (excluding the Investor's $3,000,000 option), (ii) the
    date that is 24 months after the effective date of the related registration
    statement or (iii) 30 months (rather than 27 months) after January 22, 1999,
    the date of the Equity Line Agreement.


<PAGE>   3
5.  The Letter Amendment extends the Company's deadline for filing a
    registration statement covering the shares of Class A Common Stock to be
    issued under the Equity Line Agreement until August 15, 1999.

        Additional information relating to the equity line financing is
incorporated by reference herein to (i) the Letter Amendment attached hereto as
Exhibit 10.1 and (ii) the Equity Line Agreement attached as an exhibit to the
Company's Current Report on Form 8-K filed with the Commission on January 25,
1999.

Item 7.  FINANCIAL STATEMENTS AND EXHIBITS

        (c)     Exhibits

                (i)     Exhibit 10.1 - Letter Amendment to Class A Common Stock
                        Investment Agreement dated March 22, 1999


                                   SIGNATURES

        Pursuant to the requirements of the Securities and Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                            AVANIR PHARMACEUTICALS

Date:  April 1, 1999                        By:\s\Gregory P. Hanson
                                            -----------------------
                                            Gregory P. Hanson
                                            Vice President, Finance and
                                            Chief Financial Officer



<PAGE>   1


                                                                    EXHIBIT 10.1



                                 March 22, 1999



AVANIR Pharmaceuticals, Inc.
9393 Towne Center Drive, Suite 200
San Diego, California 92121


Attention:  Gregory P. Hanson


               RE:    CLASS A COMMON STOCK INVESTMENT AGREEMENT


Dear Mr. Hanson:

        We refer to the Class A Common Stock Investment Agreement dated as of
January 22, 1999 (the "Investment Agreement") by and among AVANIR
Pharmaceuticals, Inc. (the "Company") and Promethean Investment Group, L.L.C.
(the "Investor") relating to the investment by the Investor of up to $10,000,000
of the Company's Class A common stock, no par value per share. Contemporaneously
with the execution and delivery of the Investment Agreement, the Company and the
Investor executed a Registration Rights Agreement (the "Registration Rights
Agreement") pursuant to which the Company agreed to provide certain registration
rights under the 1933 Act, and the rules and regulations promulgated thereunder,
and applicable state securities laws.

        The Company and the Investor have agreed to the following changes to the
Investment Agreement:

        1. The first sentence of Section 1(c) is amended to read as follows:

           At least 10 days but not more than 20 days prior to the Company's
           delivery of a Put Notice to the Investor, the Company shall deliver
           written notice to the Investor (a "PRELIMINARY PUT NOTICE") stating
           that the Company may deliver a Put Notice to the Investor; provided,
           however, that, following a Purchase Period, the Company shall not
           deliver a Preliminary Put Notice on or prior to the date which is 5
           Business Days after the last day of the Purchase Period.

        2. Section 1(e) is amended and restated in its entirety as follows:

           Limitation on Investor's Obligation to Purchase Shares.
           Notwithstanding anything to the contrary in this Agreement, in no
           event shall the Investor be required to purchase, and a Required
           Dollar Amount may not include, an amount, which when added to the sum
           of (i) the additional number of Shares which the Investor has the
           right to purchase with respect to such Required Dollar Amount (as set
           forth in the second sentence of Section 1(d)), (ii) all other Shares
           acquired by the Investor pursuant to this Agreement during the 61
           days preceding the Put Notice Date with respect to which this
           determination of the permitted Required Dollar Amount is being made
           and (iii) the number of shares of Class A Common Stock acquired by
           any affiliate of the Investor pursuant to conversion of the Company's
           Series D Convertible Preferred Stock (the "PREFERRED STOCK") or
           exercise of the warrants issued pursuant to the Securities Purchase
           Agreement (as defined below) or otherwise during the 61 days
           preceding the Put Notice Date with respect to which this
           determination of the permitted Required Dollar Amount is being made,
           would exceed 4.99% of the number of shares of Class A Common Stock
           outstanding on the Put Notice Date for such Purchase Period, as
           determined in accordance with Section 13(d) of the Securities
           Exchange Act of 1934, as amended (the "1934 ACT"). Each Put Notice
           shall include a representation of the Company as to the number of
           shares of Class A Common Stock outstanding on the related Put Notice
           Date as determined in accordance with Section 13(d) of the 1934 Act.
           In the event that the number of shares of Class A Common Stock
           outstanding as determined in accordance with Section 13(d) of the
           1934 Act is different on any date during a Purchase Period than on
           the Put Notice Date associated with such Purchase Period, then the



<PAGE>   2

Gregory P. Hanson
AVANIR Pharmaceuticals, Inc.
March 22, 1999
Page 4



           number of shares of Class A Common Stock outstanding on such date
           during such Purchase Period shall govern for purposes of determining
           whether the Investor, when aggregating all purchases of shares of
           Class A Common Stock by the Investor and its affiliates in the 61
           days preceding such date, would have acquired more than 4.99% of the
           number of shares of Class A Common Stock outstanding during such
           period.

        3. Section 1(f) is amended and restated in its entirety as follows:

           Conditions to Investor's Obligation to Purchase Shares.
           Notwithstanding anything to the contrary in this Agreement, the
           Company shall not be entitled to deliver a Put Notice and require the
           Investor to purchase any Shares at a Closing (as defined in Section
           1(h)) unless each of the following conditions are satisfied: (i) the
           Applicable Trading Price of the Class A Common Stock on the Business
           Day immediately preceding the Put Notice Date shall not be less than
           $1.00 (equitably adjusted for stock splits, stock dividends,
           combinations and similar transactions); (ii) a Registration Statement
           shall have been declared effective and shall remain effective and
           available for sale of all the Registrable Securities (as defined in
           the Registration Rights Agreement) at all times during the period
           beginning on the date of delivery of the related Preliminary Put
           Notice and ending on and including the related Closing Date (as
           defined in Section 1(h)); (iii) at all times during the period
           beginning on the date that the Company delivers the related
           Preliminary Put Notice and ending on and including the related
           Closing Date, the Class A Common Stock shall have been listed on The
           American Stock Exchange, Inc. or The New York Stock Exchange, Inc. or
           designated on the Nasdaq National Market (the "PRINCIPAL MARKET") and
           shall not have been suspended from trading thereon and the Company
           shall not have been notified of any pending or threatened (except as
           set forth in the letter to the Company dated February 8, 1999 from
           the Nasdaq Stock Market, Inc., provided that the Company has
           satisfied the requirements set forth in such letter) proceeding or
           other action to delist or suspend the Class A Common Stock; (iv)
           during the period beginning on the date of this Agreement and ending
           on and including the applicable Closing Date, there shall not have
           occurred a Major Transaction (as defined below) or the public
           announcement of a pending Major Transaction which has not been
           abandoned or terminated; (v) the Company has complied with its
           obligations and is otherwise not in breach of, or in default under,
           this Agreement, the Registration Rights Agreement, the Securities
           Purchase Agreement dated as of March 22, 1999 between the Company and
           the buyers named therein relating to the sale by the Company of the
           Preferred Stock and related warrants (the "SECURITIES PURCHASE
           AGREEMENT"), and the Certificate of Determination of the Company's
           Series D Convertible Preferred Stock; (vi) during the period
           beginning on the date of this Agreement and ending on and including
           the applicable Closing Date, there shall not have occurred a
           Triggering Event (as defined in the Securities Purchase Agreement);
           and (vii) if any shares of Preferred Stock are outstanding or if any
           Additional Preferred Shares (as defined in the Securities Purchase
           Agreement) are issuable pursuant to the Securities Purchase
           Agreement, then the Company shall have obtained the approval of its
           shareholders for the Company's issuance of (A) all of the Class A
           Common Stock as described in this Agreement and (B) all of the
           Securities (as defined in the Securities Purchase Agreement) as
           described in the Securities Purchase Agreement. If any of the
           conditions described in clauses (ii) through (vi) is not satisfied
           after an effective Put Notice is so delivered, and if any such
           condition described above is not satisfied at all times before the
           entire Required Dollar Amount of Class A Common Stock covered by such
           Put Notice shall have been purchased during the Purchase Period, then
           the Investor shall have no further obligation to purchase the balance
           of such Required Dollar Amount of Class A Common Stock during such
           Purchase Period; provided, however, that on any day during the
           balance of such Purchase Period upon which such conditions described
           in clauses (ii) through (vi) above are not satisfied, the Investor
           may, in its sole discretion, but shall not be required to, give the
           Company one or more Purchase Notices



<PAGE>   3

Gregory P. Hanson
AVANIR Pharmaceuticals, Inc.
March 22, 1999
Page 5



           (as defined in Section 1(h)) covering some or all of such balance of
           the Required Dollar Amount, as well as some or all of the additional
           amounts of Class A Common Stock which the Investor may elect to
           purchase during such Purchase Period pursuant to Section 1(d) above.
           The "APPLICABLE TRADING PRICE" with respect to the Class A Common
           Stock on any Business Day, shall mean the Weighted Average Price (as
           defined below) of the Class A Common Stock on such Business Day.
           "WEIGHTED AVERAGE PRICE" means, for any security as of any date, the
           dollar volume-weighted average price for such security on the
           Principal Market (as reported by Bloomberg through its "Volume at
           Price" function) or, if the Principal Market is not the principal
           securities exchange or trading market for such security, the dollar
           volume-weighted average price of such security on the principal
           securities exchange or trading market where such security is listed
           or traded (as reported by Bloomberg through its "Volume at Price"
           function), or if the foregoing do not apply, the dollar
           volume-weighted average price of such security in the
           over-the-counter market on the electronic bulletin board for such
           security as reported by Bloomberg, or, if no dollar volume-weighted
           average price is reported for such security by Bloomberg, the average
           of the bid prices of any market makers for such security as reported
           in the "pink sheets" by the National Quotation Bureau, Inc. If the
           Weighted Average Price cannot be calculated for such security on such
           date on any of the foregoing bases, the Weighted Average Price of
           such security on such date shall be the fair market value as mutually
           determined by the Company and the Investor.

           For purposes of this Agreement, a "MAJOR TRANSACTION" shall be deemed
           to have occurred at the closing of any of the following events: (i)
           the consolidation, merger or other business combination of the
           Company with or into another person (other than pursuant to a
           migratory merger effected solely for the purposes of changing the
           jurisdiction of incorporation of the Company); (ii) the sale or
           transfer of all or substantially all of the Company's assets; or
           (iii) the consummation of a purchase, tender or exchange offer made
           to, and accepted by, the holders of more than 30% of the economic
           interest in, or the combined voting power of all classes of voting
           stock of, the Company.

        4. Section 1(l) is amended and restated in its entirety as follows:

           Overall Limit on Class A Common Stock Issuable. Notwithstanding
           anything contained herein to the contrary, the number of Shares
           issuable by the Company and purchasable by the Investor hereunder
           shall not exceed that number of shares of Class A Common Stock which
           the Company may issue hereunder without breaching the Company's
           obligations, if any, under the rules or regulations of the Nasdaq
           Stock Market or such exchange on which the stock is then traded (the
           "MAXIMUM COMMON STOCK ISSUANCE"), unless the issuance of Shares
           hereunder in excess of the Maximum Common Stock Issuance shall first
           be approved by the Company's shareholders in accordance with
           applicable law and the By-laws and Articles of Incorporation of the
           Company. Without limiting the generality of the foregoing, such
           shareholders' approval must duly authorize the issuance by the
           Company of shares of Class A Common Stock totaling 19.99% or more of
           the shares of Class A Common Stock outstanding on the date hereof.
           The parties understand and agree that the Company's failure to seek
           or obtain such shareholder approval shall in no way adversely affect
           the validity and due authorization of the issuance and sale of Shares
           hereunder or the Investor's obligation in accordance with the terms
           and conditions hereof to purchase a number of Shares in the aggregate
           up to the Maximum Common Stock Issuance limitation, and that such
           approval pertains only to the applicability of the Maximum Common
           Stock Issuance limitation provided in this Section 1(l).





<PAGE>   4

Gregory P. Hanson
AVANIR Pharmaceuticals, Inc.
March 22, 1999
Page 6



        5. Section 8(b) is amended and restated in its entirety as follows:

           Automatic Termination. This Agreement shall automatically terminate
           without any further action of either party hereto upon the earlier of
           (i) when the Investor has purchased an aggregate of $10,000,000 in
           the Class A Common Stock of the Company pursuant to this Agreement,
           apart from additional amounts which may be purchased pursuant to
           Section 1(d); provided that the representations, warranties and
           covenants contained in this Agreement insofar as applicable to the
           transactions consummated hereunder prior to such termination, shall
           survive the termination of this Agreement for the period of any
           applicable statute of limitations, (ii) on the date which is 24
           months after the Effective Date or (iii) on the date which is 30
           months after the date hereof.

           All representations, warranties and covenants shall survive the
           termination of this Agreement.

        6. Section 10(b)(i) is amended and restated in its entirety as follows:

           As an inducement to the Investor to enter into this Agreement, the
           Company shall deliver to the Investor on the date hereof an amount
           equal to $100,000 by wire transfer of immediately available funds. As
           a further inducement to the Investor to enter into this Agreement,
           the Company shall pay to the Investor the "SECOND INSTALLMENT," the
           definition of which will depend on whether or not the Registration
           Statement is filed with the SEC on or prior to August 15, 1999. If
           the Registration Statement is not filed on or prior to August 15,
           1999, then the Second Installment shall mean that the Company shall
           deliver to the Investor an amount equal to $150,000 by wire transfer
           of immediately available funds within one Business Day of August 15,
           1999. If the Registration Statement is filed on or prior to August
           15, 1999, then the Second Installment shall mean (A) if the
           Registration Statement is declared effective by the SEC on or before
           the date which is 45 days after the date the Registration Statement
           is filed with the SEC, then within one Business Day of the date that
           the Registration Statement is declared effective by the SEC, the
           Company shall deliver to the Investor either (x) an amount equal to
           $150,000 by wire transfer of immediately available funds or (y) stock
           certificates representing the number of Shares (the "FIRST COMMITMENT
           SHARES") having an aggregate price (based on a price per First
           Commitment Share equal to 94% of the lowest Applicable Trading Price
           during the six consecutive trading days ending on and including the
           date the Registration Statement is declared effective) of $150,000,
           and (B) if the Registration Statement is not declared effective on or
           before the date which is 45 days after the date the Registration
           Statement is filed with the SEC, then (x) the Company, on the first
           Business Day after such 45th day, shall pay to the Investor an amount
           equal to $50,000 by wire transfer of immediately available funds and
           (y) on the earlier of the date on which the Registration Statement is
           declared effective by the SEC and the date which is 75 days after the
           date the Registration Statement is filed with the SEC, the Company,
           on the first Business Day after such date, shall deliver to the
           Investor either (i) an amount equal to $100,000 by wire transfer of
           immediately available funds or (ii) provided that the Registration
           Statement is declared effective by the SEC on or before the date
           which is 75 days after the date the Registration Statement is filed
           with the SEC, stock certificates representing the number of Shares
           (the "SECOND COMMITMENT SHARES" and, collectively with the First
           Commitment Shares, the "COMMITMENT SHARES") having an aggregate price
           (based on a price per Second Commitment Share equal to 94% of the
           lowest Applicable Trading Price during the six consecutive trading
           days ending on and including the date the Registration Statement is
           declared effective) of $100,000 (in any such case, and along with the
           amount described in the first sentence of this Section 10(b)(i), the
           "COMMITMENT FEE"). The Company shall notify the Investor of the
           Company's election to make the payments described in the immediately
           preceding sentence in cash or in Commitment Shares by delivering
           written notice to the Investor at least three Business Days prior to
           the date that such payment is due. Notwithstanding


                                     
<PAGE>   5

Gregory P. Hanson
AVANIR Pharmaceuticals, Inc.
March 22, 1999
Page 7



           anything herein to the contrary, the Company may pay the portion of
           the Commitment Fee described in the second sentence of this Section
           10(b)(i) in Commitment Shares if, and only if, at the time of their
           delivery, such Commitment Shares are registered for public resale
           under the 1933 Act and state securities laws and listed or quoted on
           the Principal Market. If the Company fails to pay any portion of the
           Commitment Fee when due, then the Company shall pay to the Investor,
           on the first Business Day following the date such payment was due (in
           addition to and not in lieu of any remedy the Investor may have in
           law or in equity) an amount equal to 2% of the Commitment Fee, in
           cash by wire transfer, plus compounded annual interest of 18% on such
           portion of the Commitment Fee during the period, beginning on the
           Business Day after such portion of the Commitment Fee was due, during
           which such amount, or any portion thereof, is outstanding. In the
           event that the Company elects to pay any the portion of the
           Commitment Fee described in the second sentence of this Section
           10(b)(i) in Commitment Shares, then to the extent possible the
           Company shall deliver such Commitment Shares through DTC.

        In addition, the Company and Promethean have agreed to the following
change to the Registration Rights Agreement:

        1.     Section 2(a) is amended and restated in its entirety as follows:

           Mandatory Registration. The Company shall prepare, and, on or prior
           to August 15, 1999, file with the SEC a Registration Statement or
           Registration Statements (as is necessary) (provided, however, that in
           no event shall such Registration Statement be filed prior to the date
           which is 45 days after the date the Convertible Registration
           Statement (as defined below) is declared effective by the SEC) on
           Form S-3 (or, if such forms is unavailable for such a registration,
           on such other form as is available for such a registration, subject
           to the consent of the Holders holding a majority of the Registrable
           Securities, which consent shall not be unreasonably withheld),
           covering the resale of all of the Registrable Securities, which
           Registration Statement(s) shall state that, in accordance with Rule
           416 promulgated under the 1933 Act, such Registration Statement(s)
           also covers such indeterminate number of additional shares of Class A
           Common Stock as may become issuable upon stock splits, stock
           dividends or similar transactions. Such Registration Statement shall
           initially register for resale 19.99% of the shares of Class A Common
           Stock outstanding (not including the 234,000 shares of common stock
           of the Company held by David H. Katz as to which there is a dispute
           as to their class) on the date the Registration Statement is filed
           with the SEC. The Company shall use its best efforts to have the
           Registration Statement(s) declared effective by the SEC as soon as
           practicable. The "CONVERTIBLE REGISTRATION STATEMENT" shall mean the
           Initial Registration Statement referred to in the registration rights
           agreement dated as of March 22, 1999 executed in connection with the
           Securities Purchase Agreement dated as of March 22, 1999 between the
           Company and the buyers named therein relating to the sale by the
           Company of shares of its Series D Convertible Preferred Stock, and
           related warrants.

        Section 3(a) is amended and restated in its entirety as follows:

           The Company shall promptly prepare and file with the SEC a
           Registration Statement with respect to the sale by the Holders of the
           Registrable Securities on or prior to August 15, 1999; provided,
           however, that in no event shall such Registration Statement be filed
           prior to the date which is 45 days after the date the Convertible
           Registration Statement is declared effective by the SEC; and use its
           best efforts to cause such Registration Statement relating to the
           Registrable Securities to become effective as soon as practicable
           after the date hereof for the registration of Registrable Securities
           pursuant to Section 2(a), and keep such Registration Statement
           effective pursuant to Rule 415 at all times until the earlier of (i)
           the date as of which the Holders may sell all of the Registrable
           Securities without restriction pursuant to Rule 144(k) promulgated
           under the 1933 Act (or successor thereto) or (ii) the date on which
           (A) the Holders shall have sold all


                                     
<PAGE>   6

Gregory P. Hanson
AVANIR Pharmaceuticals, Inc.
March 22, 1999
Page 8



           the Registrable Securities and (B) the Investor has no right to
           acquire any additional shares of Class A Common Stock under the
           Investment Agreement (the "REGISTRATION PERIOD"), which Registration
           Statement (including any amendments or supplements thereto and
           prospectuses contained therein) shall not contain any untrue
           statement of a material fact or omit to state a material fact
           required to be stated therein, or necessary to make the statements
           therein, in light of the circumstances in which they were made, not
           misleading.

        Except as modified above, the Investment Agreement and the Registration
Rights Agreement remain in full force and effect in accordance with their terms.

        The Company agrees that, on or before the first (1st) Business Day after
the Initial Closing Date (as defined in the Securities Purchase Agreement, dated
March 22, 1999, among the Company and the Buyers named therein relating to the
Company's Series D Convertible Preferred Stock), the Company shall publicly
disclose the terms of this letter agreement by filing a Current Report on Form
8-K, which Current Report on Form 8-K shall include a description of the
material terms of this letter agreement and shall include as an exhibit a copy
of this letter agreement.

        This letter agreement is effective March 22, 1999 and shall be binding
upon the parties and their successors and assigns and may be amended or
terminated only by a writing signed by all the parties hereto.



                                   *   *   *


<PAGE>   7


        Please indicate your agreement to the above by signing in the space
provided below and faxing a signed copy to each of the Buyers listed below.



PROMETHEAN INVESTMENT GROUP, L.L.C.:


By: \s\E. Kurt Kim
Name:   E. Kurt Kim
Title:  Authorized Signatory

                                          Accepted and agreed to this
                                          22nd day of March, 1999:

                                          AVANIR PHARMACEUTICALS, INC.


                                          By:  /s/ Gregory P. Hanson
                                              ----------------------------------
                                                   Gregory P. Hanson
                                                   Chief Financial Officer









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