AVANIR PHARMACEUTICALS
DEFS14A, 1999-04-13
PHARMACEUTICAL PREPARATIONS
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<PAGE>   1
 
                            SCHEDULE 14A INFORMATION
                                (Rule 14a-101)
 
                  PROXY STATEMENT PURSUANT TO SECTION 14(A) OF
             THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )
 
Filed by the Registrant [X]
 
Filed by a Party other than the Registrant [ ]
 
Check the appropriate box:
 
[ ]  Preliminary Proxy Statement                
[ ]  Confidential, for Use of the Commission Only
     (as permitted by Rule 14a-6(e)(2))
[X]  Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to sec.240.14a-11(c) or sec.240.14a-12
 
                            AVANIR PHARMACEUTICALS
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)
 
- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)
 
Payment of Filing Fee (Check the appropriate box):
 
[X]  No fee required.
 
[ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.
 
     (1)  Title of each class of securities to which transaction applies:
 
     (2)  Aggregate number of securities to which transaction applies:
 
     (3)  Per unit price or other underlying value of transaction computed
          pursuant to Exchange Act Rule 0-11 (Set forth the amount on which the
          filing fee is calculated and state how it was determined):
 
     (4)  Proposed maximum aggregate value of transaction:
 
     (5)  Total fee paid:
 
[ ]  Fee paid previously with preliminary materials.
 
[ ]  Check box if any part of the fee is offset as provided by Exchange Act Rule
     0-11(a)(2) and identify the filing for which the offsetting fee was paid
     previously. Identify the previous filing by registration statement number,
     or the Form or Schedule and the date of its filing.
 
     (1)  Amount Previously Paid:
 
     (2)  Form, Schedule or Registration Statement No.:
 
     (3)  Filing Party:
 
     (4)  Date Filed:
<PAGE>   2
 
                             AVANIR PHARMACEUTICALS
                       9393 TOWNE CENTRE DRIVE, SUITE 200
                        SAN DIEGO, CALIFORNIA 92121-3016
 
                            ------------------------
 
                   NOTICE OF SPECIAL MEETING OF SHAREHOLDERS
                           TO BE HELD ON MAY 11, 1999
                            ------------------------
 
     We will hold a Special Meeting of Shareholders on May 11, 1999, at 11:00
a.m., at our offices at 9393 Towne Centre Drive, Suite 200, San Diego,
California 92121, for the following purposes:
 
     1. Approve the issuance of more than 20% of the outstanding shares of Class
        A Common Stock pursuant to certain financing transactions.
 
     2. Transact such other business as may properly come before the meeting or
        any adjournment or postponement of the meeting.
 
     The foregoing items of business are more fully described in the Proxy
Statement accompanying this Notice.
 
     Only shareholders of record at the close of business on March 25, 1999 will
be entitled to notice of and to vote at the meeting or any adjournment thereof.
As a shareholder, you are cordially invited to be present and vote at the
meeting in person.
 
                                          By Order of the Board of Directors,
                                          /s/ Gregory P. Hanson
                                          GREGORY P. HANSON
                                          Secretary
 
San Diego, California
   
April 13, 1999
    
 
     PLEASE ENTER YOUR VOTE, SIGN AND DATE THE ENCLOSED PROXY CARD AND RETURN IT
PROMPTLY IN THE ENCLOSED ENVELOPE. YOUR VOTE IS VERY IMPORTANT TO US. A MAJORITY
OF THE ISSUED AND OUTSTANDING SHARES MUST BE REPRESENTED, EITHER IN PERSON OR BY
PROXY, TO CONSTITUTE A QUORUM FOR THE MEETING. IF YOU ATTEND THE MEETING, YOU
MAY VOTE IN PERSON EVEN THOUGH YOU SEND IN YOUR PROXY NOW.
<PAGE>   3
 
                             AVANIR PHARMACEUTICALS
 
                                PROXY STATEMENT
                                      FOR
 
                        SPECIAL MEETING OF SHAREHOLDERS
                           TO BE HELD ON MAY 11, 1999
 
                               TABLE OF CONTENTS
 
<TABLE>
<CAPTION>
                                                              PAGE
                                                              ----
<S>                                                           <C>
GENERAL INFORMATION.........................................    1
 
SHARES OUTSTANDING AND VOTING RIGHTS........................    1
 
PROPOSAL ONE
  APPROVAL OF ISSUANCE OF MORE THAN 20% OF THE OUTSTANDING
     SHARES OF CLASS A COMMON STOCK.........................    6
 
OTHER BUSINESS..............................................    8
 
ATTACHMENT A -- DESCRIPTION OF THE PREFERRED STOCK
  AGREEMENT, SERIES D PREFERRED STOCK, THE WARRANTS AND THE
  EQUITY LINE AGREEMENT.....................................  A-1
</TABLE>
 
                                        i
<PAGE>   4
 
                             AVANIR PHARMACEUTICALS
                       9393 TOWNE CENTRE DRIVE, SUITE 200
                        SAN DIEGO, CALIFORNIA 92121-3016
 
                            ------------------------
 
                              PROXY STATEMENT FOR
                        SPECIAL MEETING OF SHAREHOLDERS
                           TO BE HELD ON MAY 11, 1999
                            ------------------------
 
                              GENERAL INFORMATION
 
     The Board of Directors (the "Board") of AVANIR Pharmaceuticals, a
California corporation (the "Company"), solicits your proxy (in the enclosed
form) for use at the special meeting of the Company's shareholders (the
"Shareholders") to be held on May 11, 1999 at 11:00 a.m. at the Company's
offices at 9393 Towne Centre Drive, Suite 200, San Diego, California 92121 (the
"Meeting"). The purposes of the Meeting are set forth in the accompanying
notice. The mailing of this Proxy Statement and the accompanying form of proxy
to the Shareholders is expected to occur on or about April 14, 1999.
 
     The shares represented by any proxy in the enclosed form will be voted in
accordance with the instructions given on the proxy if the proxy is properly
executed and is received by the Company prior to the close of voting at the
Meeting or any adjournment or postponement thereof. Proxies received by the
Company on which no contrary instruction has been given will be voted "FOR" the
issuance of more than 20% of the Company's outstanding shares of Class A Common
Stock and, as recommended by the Board of Directors in its discretion, with
regard to all other matters which may properly come before the Meeting. A
shareholder giving a proxy has the power to revoke it at any time before it is
exercised. A proxy may be revoked by filing with the Secretary of the Company an
instrument revoking it or a duly executed proxy bearing a later date. The powers
of the proxy holders will be suspended if the person executing the proxy is
present at the Meeting and votes in person.
 
     Copies of solicitation material will be furnished to brokerage houses,
fiduciaries, and custodians holding shares in their names which are beneficially
owned by others ("record holders") to forward such material to the beneficial
owners. The Company may reimburse such persons for their cost of forwarding the
solicitation material to the beneficial owners. Original solicitation of proxies
by mail may be supplemented, if deemed desirable or necessary, by one or more of
telephone, telegram, facsimile, or personal solicitation by directors, officers,
or employees of the Company. The Company will not pay any additional
compensation to its directors, officers or employees for any such services. The
Company reserves the right, if deemed desirable or necessary, to retain a proxy
solicitation firm or other third parties to deliver solicitation material to
record holders for distribution by them to the beneficial owners and to assist
the Company in collecting or soliciting proxies from such holders. The costs of
these services, exclusive of out-of-pocket costs, is not expected to exceed
$25,000. Except as described above, the Company does not intend to solicit
proxies other than by mail.
 
                      SHARES OUTSTANDING AND VOTING RIGHTS
 
     Only holders of shares of Class A Common Stock and Class B Common Stock of
record as of the close of business on March 25, 1999 are entitled to notice of
and to vote at the Meeting. On the record date, there were issued and
outstanding 40,941,292 shares of Class A Common Stock and 65,000 shares of Class
B Common Stock (collectively, the "Shares"). (There is currently a dispute with
Dr. David H. Katz, the former president and chief executive officer and a former
director of the Company, as to the status of certain of his shares of Class A
Common Stock and Class B Common Stock. See Footnotes 20 and 21 to "Security
Ownership of Certain Beneficial Owners and Management"). Each share of Class A
Common Stock is entitled to one vote and each share of Class B Common Stock is
entitled to five votes on all matters to be voted on at the Meeting.
 
                                        1
<PAGE>   5
 
     The presence, in person or by proxy duly authorized, of the holders of a
majority of the Shares will constitute a quorum for the transaction of business
at the Meeting and any continuation or adjournment thereof. Shares that are
voted "FOR", "AGAINST" or "ABSTAIN" on a proposal are treated as being present
at the Meeting for the purpose of establishing a quorum and are treated as
shares entitled to vote at the Meeting ("Votes Cast") with respect to such
proposal.
 
     The proposal to issue more than 20% of the Company's outstanding shares of
Class A Common Stock, submitted to the Shareholders in the enclosed proxy, must
be approved by the vote of a majority of the Votes Cast, whether in person or by
proxy. Abstentions therefore will have the same effect as a vote against the
proposal. Broker non-votes (i.e. shares held by a broker or nominee which are
represented at the Meeting, but with respect to which such broker or nominee is
not empowered to vote on a particular purpose) will be counted for the broker
purpose of establishing a quorum for the transaction of business, but such
non-votes will not be counted for purposes of determining the number of Votes
Cast with respect to the particular proposal on which a broker has expressly not
voted. A broker non-vote will not affect the outcome of the voting on a
proposal.
 
     Your execution of the enclosed proxy will not affect your right as a
shareholder to attend the Meeting and to vote in person. Any Shareholder giving
a proxy has a right to revoke it at any time by either (i) a later-dated proxy,
(ii) a written revocation sent to and received by the Secretary of the Company
prior to the Meeting, or (iii) attendance at the Meeting and voting in person.
 
                                        2
<PAGE>   6
 
                         SECURITY OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT
 
     The following table sets forth certain information regarding the beneficial
ownership (as defined by Rule 13d-3 under the Securities Exchange Act of 1934,
as amended (the "Exchange Act")) of the Company's voting shares (Class A Common
Stock and Class B Common Stock) as of March 25, 1999 by: (i) each director and
named executive officer of the Company; (ii) all current executive officers and
directors of the Company as a group; and (iii) each person or "group" of persons
(as defined under Section 13(d)(3) of the Exchange Act) known by the Company to
own beneficially 5% or more of the outstanding shares or voting power of the
Company's voting securities. The table is based upon information supplied by
directors, officers and principal shareholders. Unless otherwise indicated, each
of the listed persons has sole voting and sole investment power with respect to
the shares of the Shares beneficially owned, subject to community property laws
where applicable.
 
<TABLE>
<CAPTION>
                                                           AMOUNT AND                 PERCENT OF
                              NAME AND ADDRESS OF          NATURE OF                    TOTAL
                                  BENEFICIAL               BENEFICIAL    PERCENT OF     VOTING
   TITLE OF CLASS        OWNER OR IDENTITY OF GROUP(1)    OWNERSHIP(2)    CLASS(2)     POWER(3)
   --------------       -------------------------------   ------------   ----------   ----------
<S>                     <C>                               <C>            <C>          <C>
Class A Common Stock    Gerald J. Yakatan(4)                 423,451       1.02%        1.02%
Class B Common Stock                                              --         --
Class A Common Stock    George P. Rutland(5)                 252,500         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Dennis J. Carlo(6)                    30,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Michael W. George(7)                  32,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    James B. Glavin(8)                    30,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Edward L. Hennessy, Jr.(9)            80,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Kenneth E. Olson(10)(11)             250,067         *            *
Class B Common Stock                                          16,000       24.62%
Class A Common Stock    Stuart A. Samuels(12)                 71,667         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Joseph E. Smith(13)                   30,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    James E. Berg(14)                    158,408         *            *
Class B Common Stock                                              --         --
Class A Common Stock    J. David Hansen(15)                   55,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Gregory P. Hanson(16)                 56,000         *            *
Class B Common Stock                                              --         --
Class A Common Stock    Timothy R. Russell(17)               285,951         *            *
Class B Common Stock                                              --         --
Class A Common Stock    All officers and directors as a    1,755,044       4.15%        4.30%
                        group
Class B Common Stock    (thirteen persons)(18)(19)            16,000       24.62%
Class A Common Stock    David H. Katz(20)(21)              3,441,193       7.97%        11.73%
Class B Common Stock                                         375,000       88.44%
</TABLE>
 
- ---------------
  *  Indicates less than one percent (1%).
 
 (1) The address for all persons shown, except for Dr. Katz, is c/o AVANIR
     Pharmaceuticals, 9393 Towne Centre Drive, Suite 200, San Diego, California
     92121. The address for Dr. Katz is 1775 La Jolla Rancho Road, La Jolla,
     California 92037.
 
 (2) Based upon 40,941,292 shares of Class A Common Stock and 65,000 shares of
     Class B Common Stock outstanding as of March 25, 1999. The percentage
     ownership and voting power for each shareholder (or
 
                                        3
<PAGE>   7
 
all directors and executive officers as a group), is calculated by assuming the
exercise or conversion of all warrants, options and convertible securities
exercisable or convertible within 60 days of March 25, 1999 held by such
     shareholder and the nonexercise and nonconversion of all other outstanding
     warrants, options and convertible securities. See Footnote 20, below.
 
 (3) Percentage of total voting power is based upon total cumulative voting
     power of Class A Common Stock and Class B Common Stock combined as of March
     25, 1999. Each share of Class A Common Stock entitles the holder to one
     vote per share on matters to be voted on by shareholders; each share of
     Class B Common Stock entitles the holder to five votes per share on matters
     to be voted on by shareholders. The percentage ownership and voting power
     for each shareholder (or all directors and executive officers as a group),
     is calculated by assuming the exercise or conversion of all warrants,
     options and convertible securities exercisable or convertible within 60
     days of March 25, 1999 held by such shareholder and the nonexercise and
     nonconversion of all other outstanding warrants, options and convertible
     securities.
 
 (4) Includes 37,500 shares of Class A Common Stock and options to purchase
     385,951 shares of Class A Common Stock. Does not include options to
     purchase 354,049 shares of Class A Common Stock which are not exercisable
     within 60 days of March 25, 1999.
 
 (5) Includes 222,500 shares of Class A Common Stock over which Mr. Rutland
     exercises sole voting and investment power, and options to purchase 30,000
     shares of Class A Common Stock. Does not include options to purchase 65,000
     shares of Class A Common Stock which are not exercisable within 60 days of
     March 25, 1999.
 
 (6) Includes options to purchase 30,000 shares of Class A Common Stock. Does
     not include options to purchase 65,000 shares of Class A Common Stock which
     are not exercisable within 60 days of March 25, 1999.
 
 (7) Includes 2,000 shares of Class A Common Stock and options to purchase
     30,000 shares of Class A Common Stock. Does not include options to purchase
     65,000 shares of Class A Common Stock which are not exercisable within 60
     days of March 25, 1999.
 
 (8) Includes options to purchase 30,000 shares of Class A Common Stock. Does
     not include options to purchase 55,000 shares of Class A Common Stock which
     are not exercisable within 60 days of March 25, 1999.
 
 (9) Includes 50,000 shares of Class A Common Stock and options to purchase
     30,000 shares of Class A Common Stock. Does not include options to purchase
     65,000 shares of Class A Common Stock which are not exercisable within 60
     days of March 25, 1999.
 
(10) Includes 36,400 shares of Class A Common Stock and options to purchase
     213,667 shares of Class A Common Stock. Does not include options to
     purchase 53,333 shares of Class A Common Stock which are not exercisable
     within 60 days of March 25, 1999.
 
(11) Includes 16,000 shares of Class B Common Stock.
 
(12) Includes options to purchase 71,667 shares of Class A Common Stock. Does
     not include options to purchase 53,333 shares of Class A Common Stock which
     are not exercisable within 60 days of March 25, 1999.
 
(13) Includes options to purchase 30,000 shares of Class A Common Stock. Does
     not include options to purchase 65,000 shares of Class A Common Stock which
     are not exercisable within 60 days of March 25, 1999.
 
(14) Includes options to purchase 158,408 shares of Class A Common Stock. Does
     not include options to purchase 130,592 shares of Class A Common Stock
     which are not exercisable within 60 days of March 25, 1999.
 
(15) Includes 5,000 shares of Class A Common Stock and options to purchase
     50,000 shares of Class A Common Stock. Does not include options to purchase
     200,000 shares of Class A Common Stock which are not exercisable within 60
     days of March 25, 1999.
 
                                        4
<PAGE>   8
 
(16) Includes 6,000 shares of Class A Common Stock and options to purchase
     50,000 shares of Class A Common Stock. Does not include options to purchase
     200,000 shares of Class A Common Stock which are not exercisable within 60
     days of March 25, 1999.
 
(17) Includes 30,000 shares of Class A Common Stock and options to purchase
     255,951 shares of Class A Common Stock. Does not include options to
     purchase 114,049 shares of Class A Common Stock which are not exercisable
     within 60 days of March 25, 1999.
 
(18) Includes 389,400 shares of Class A Common Stock and options to purchase
     1,365,644 shares of Class A Common Stock. Does not include 1,485,356
     options to purchase Class A Common Stock not exercisable within 60 days of
     March 25, 1999.
 
(19) Includes 16,000 shares of Class B Common Stock.
 
(20) Dr. Katz ceased to serve as a director of the Company on February 19, 1999.
     Table includes 1,196,003 shares of Class A Common Stock held by Dr. Katz
     and 2,000 shares held by his wife, options to purchase 1,827,000 shares of
     Class A Common Stock and 386,190 shares of Class A Common Stock issuable
     upon the exercise of Class D Warrants and options to purchase 30,000 shares
     of Class A Common Stock held by his wife.
 
     In Amendment No. 2 to Schedule 13D dated September 3, 1998 (the "Schedule
     13D Amendment No. 2"), filed by Dr. Katz with the Securities and Exchange
     Commission (the "SEC"), Dr. Katz stated that he and his wife (collectively,
     the "Katz Parties") entered into a Settlement and Rescission Agreement to
     settle certain litigation with Mitchell J. Stein, HealthMed, Inc.
     ("HealthMed"), National Trust Properties and the Trammel Trust
     (collectively, the "HealthMed Parties") relating to the Stock Purchase
     Agreement, the Purchase Rights Agreement, the Voting Trust Agreement, each
     dated January 12, 1998, between Dr. Katz and HealthMed, and the Promissory
     Note entered into between Dr. Katz and HealthMed on January 12, 1998
     (collectively the "Katz Agreements") as described in Amendment No. 1 to
     Schedule 13D filed by Dr. Katz, dated March 27, 1998. Pursuant to the terms
     of the Settlement and Rescission Agreement ("Settlement Agreement") and
     related court order, the Katz Agreements have been rescinded in their
     entirety as between the parties. Dr. Katz has taken the position that one
     effect of the Settlement Agreement is that 234,000 shares of Common Stock
     (which had converted into Class A Common Stock at the date the Katz
     Agreements were executed by operation of the Company's Articles of
     Incorporation which require such conversion upon transfer of the shares of
     Class B Common Stock into trust) should be reinstated to shares of Class B
     Common Stock. The Company has informed Dr. Katz that it disagrees with his
     claim that these shares of Class A Common Stock should be reclassified to
     shares of Class B Common Stock based on its interpretation of its Articles
     of Incorporation. (These shares are referred to below as the "Disputed
     shares of Class A Common Stock.") Dr. Katz is seeking a judicial
     determination of his rights to shares of Class B Common Stock (in lieu of
     the Disputed shares of Class A Common Stock) under the Company's Articles
     of Incorporation. If Dr. Katz obtains a determination in his favor in
     advance of the Meeting, the Company intends to provide to Dr. Katz the
     voting rights he would have enjoyed had he held these shares of Class B
     Common Stock on the Record Date of the Meeting. The effect of such a
     determination could increase Dr. Katz's voting rights by as much as 936,000
     votes and his beneficial ownership to as high as 14%. Dr. Katz has further
     stated in his Amendment No. 3 to Schedule 13D dated September 18, 1998
     ("Schedule 13D Amendment No. 3") that he is the beneficial owner of
     3,264,096 share of Class A Common Stock and 619,000 shares of Class B
     Common Stock. Of that total, he states that he has the sole power to vote
     and dispose of 3,215,193 shares of Class A Common Stock and 609,000 shares
     of Class B Common Stock, and that his wife has the sole power to vote and
     dispose of 46,903 shares of Class A Common Stock and 10,000 shares of Class
     B Common Stock. The Schedule 13D Amendment No. 3 reports the 234,000
     Disputed shares of Class A Common Stock as shares of Class B Common Stock
     in the number of shares of Class B Common Stock Dr. Katz reports as
     beneficially owned. As discussed above, the Company treats these shares as
     outstanding shares of Class A Common Stock. Additionally, Dr. Katz' filing
     appears to include canceled options to purchase 40,000 and 14,952 shares of
     Class A Common Stock issued to Dr. Katz and his wife, respectively, and
     10,000 canceled options to exercise Class B Common Stock issued to his
     wife. Such options have been
 
                                        5
<PAGE>   9
 
canceled because the options were not exercised within the defined exercise
period specified by the stock option plans following the termination dates of
employment.
 
(21) Includes options to purchase 375,000 shares of Class B Common Stock. On
     June 1, 1998, Dr. Katz notified the Company of his intent to exercise his
     right to purchase 375,000 shares of Class B Common Stock under a
     non-qualified stock option grant. The Company did not fulfill Dr. Katz's
     request for exercise of the option at that time because he previously
     signed a commitment letter to the Company in June 1996 in which he agreed
     not to exercise his option until an adequate number of Class B Shares were
     available. On February 19, 1999, the shareholders approved an amendment to
     the Company's Articles of Incorporation to reapportion the allocation of
     the authorized number of shares of common stock to allow for a sufficient
     number of shares of Class B Common Stock underlying all Class B stock
     options. On March 5, 1999, the Company notified Dr. Katz that it would
     honor his request to exercise his stock option, provided he paid the
     applicable federal and state withholding taxes to the Company. Dr. Katz has
     not made the withholding tax payments to the Company, and he disputes the
     Company's right to require such payments. As a result, the Company has not
     honored his request to exercise the option.
 
                                  PROPOSAL ONE
                     APPROVAL OF ISSUANCE OF MORE THAN 20%
                   OF THE OUTSTANDING SHARES OF COMMON STOCK
                           (ITEM 1 ON THE PROXY CARD)
 
OVERVIEW
 
   
     The Company has entered into two financing arrangements with certain
investors -- an offering of shares of its Series D Convertible Preferred Stock
and an investment equity line. The purpose of the financing arrangements is to
raise potentially up to $18 million in capital to enable the Company to pursue
its current marketing plan with respect to docosanol cream and to provide
working capital for operations, including continuing current research and
development programs. Because the aggregate number of shares of Class A Common
Stock potentially issuable under these two arrangements may exceed 20% of the
currently outstanding shares of Class A Common Stock at a purchase price below
market value at the time of issuance, the Company must obtain the approval of
its shareholders in accordance with the rules of The Nasdaq Stock Market, Inc.
and pursuant to the financing agreements to issue more than 20% of such shares.
    
 
     Issuance and Sale of Shares of Series D Convertible Preferred Stock and
Warrants. On March 22, 1999, the Company entered into a Securities Purchase
Agreement (the "Preferred Stock Agreement") with certain investors (the "Series
D Investors"), pursuant to which the Company has raised $2,000,000 through the
issuance and sale to the Series D Investors of (i) 200 shares of Series D
Convertible Preferred Stock (with the rights, preferences and privileges
described in Attachment A to this Proxy Statement) (the "Series D Preferred
Stock"), and (ii) an equal number of five-year warrants ("Warrants"), each
exercisable into 500 shares of Class A Common Stock. The Series D Investors also
will be required to purchase 100 additional shares of Series D Preferred Stock
and an equal number of related Warrants for additional proceeds to the Company
of $1,000,000, subject to the satisfaction of certain conditions described in
the Preferred Stock Agreement. In addition, the Series D Investors will have the
right to purchase up to 200 additional shares of Series D Preferred Stock and an
equal number of related Warrants for additional proceeds to the Company of up to
$2,000,000, subject to the satisfaction of certain conditions described in the
Preferred Stock Agreement. The purchase price for one share of Series D
Preferred Stock and the related Warrant is $10,000.
 
     The Series D Investors may convert any or all of the shares of Series D
Preferred Stock that they acquire into fully paid and nonassessable shares of
Class A Common Stock at a conversion rate equal to $10,000 divided by a
conversion price equal to the lesser of (i) the Fixed Conversion Price (as
defined below) or (ii) the Variable Conversion Price (as defined below). The
"Fixed Conversion Price" is equal to (a) $1.05 per share of Class A Common Stock
during the first 120 calendar days following the initial closing, and (b)
thereafter, 120% of the five-day average of the closing bid prices per share of
the Class A Common Stock during the five (5) trading days immediately preceding
the 121st calendar day after the initial closing (subject
 
                                        6
<PAGE>   10
 
to adjustment if the Company does not secure a line of credit for at least
$2,000,000 within 110 days after the initial closing). The "Variable Conversion
Price" is equal to (x) 100% of the Market Price (as defined below) during the
first 75 calendar days following the initial closing for shares of Class A
Common Stock and (y) thereafter, 86% of the Market Price. The Series D Investors
and their respective affiliates may not convert, however, a number of shares of
Series D Preferred Stock that would result in their beneficial ownership
exceeding 4.99% of the total outstanding shares of Class A Common Stock
following such conversion.
 
     In addition, the exercise price of the Warrants is equal to (i) $1.05 per
share of Class A Common Stock during the first 120 calendar days after the
initial closing, and (ii) thereafter, 120% of the five-day average of the
closing bid prices of the Class A Common Stock immediately preceding the 121st
calendar day (subject to adjustment in the event that the Company does not
secure a line of credit for at least $2,000,000 within the first 110 days after
the initial closing).
 
     Equity Line Agreement. The Company also entered into a Class A Common Stock
Investment Agreement (the "Equity Line Agreement") with an investment fund (the
"Equity Line Investor"). Pursuant to the Equity Line Agreement, the Company may
cause the Equity Line Investor to purchase up to $10,000,000 in shares of Class
A Common Stock (the "Equity Line Shares"). The Company will sell the Equity Line
Shares at the higher of (i) a six percent (6%) discount from market price of the
shares of Class A Common Stock or (ii) subject to certain stock price and
trading volume conditions, a designated fixed price set by the Company. The
Company must satisfy certain other conditions, including the approval of this
proposal by the Company's shareholders. The Equity Line Agreement also gives to
the Equity Line Investor the option to purchase up to an additional $3,000,000
in shares of Class A Common Stock by purchasing such shares in amounts equal to
30% of the respective dollar amounts that the Company sets forth in its "put"
notices to the Equity Line Investor.
 
     The Equity Line Agreement and the Preferred Stock Agreement are referred to
below, collectively, as the "Investment Agreements." A summary of certain terms
and conditions of the Series D Preferred Stock, Warrants and the Investment
Agreements are described in Attachment A to this Proxy Statement.
 
   
     Requirement of Shareholder Approval. The Class A Common Stock is traded on
the Nasdaq National Market System. Nasdaq requires the Company to obtain
shareholder approval in connection with the sale or issuance of shares of its
Class A Common Stock (or securities convertible into or exercisable for shares
of Class A Common Stock) when (i) the number of additional shares of Class A
Common Stock being issued equals or exceeds 20% of the number of shares of Class
A Common Stock that are outstanding prior to such sale or issuance and (ii) the
shares of Class A Common Stock will be sold at a price per share which is less
than the greater of the (x) per share book value or (y) per share market value
of the shares of Class A Common Stock at the time of such sale or issuance. The
Company is seeking shareholder approval of this proposal, because the aggregate
number of shares of Class A Common Stock issuable under the Preferred Stock
Agreement and the Equity Line Agreement likely will exceed 20% of the currently
outstanding shares of Class A Common Stock, and will be less than the per share
market value at the time of issuance.
    
 
     If the shareholders approve this proposal, then the Company will apply to
list on Nasdaq the additional shares of Class A Common Stock to be issued under
the Investment Agreements.
 
EFFECT OF THE FAILURE TO APPROVE THIS PROPOSAL
 
     Failure to obtain shareholder approval of this proposal (i) will make
unavailable to the Company the financing pursuant to the Equity Line Agreement
so long as any shares of Series D Preferred Stock are outstanding, (ii) will
limit the number of shares of Class A Common Stock that can be issued, (iii) may
result in the Company paying certain penalties and/or redeeming certain shares
of Series D Preferred Stock at a premium, and (iv) will limit the Company's
ability to finance continuing operations. The Company has agreed, among other
things, to pay certain penalties under the Preferred Stock Agreement if the
Meeting is not held on or before May 31, 1999 or if this proposal is not
approved by the shareholders at the Meeting. In addition, if the Series D
Investors are not able to exercise their conversion rights because the Company
has not received approval for the issuance of greater than 20% of the
outstanding shares of Class A Common Stock, then the Series D Investors may,
with respect to the unconverted shares of Series D Preferred Stock, require
                                        7
<PAGE>   11
 
the Company to redeem and retain such shares of Series D Preferred Stock. If the
Company is unable or refuses to redeem such shares, then the Series D Investors
may cause the Company to be delisted from Nasdaq.
 
CERTAIN RISKS OF THE ISSUANCE OF SHARES OF SERIES D PREFERRED STOCK AND WARRANTS
AND SHARES OF CLASS A COMMON STOCK UNDER THE EQUITY LINE
 
     Potential Dilution. Due to the indeterminate nature of the conversion price
of the shares of Series D Preferred Stock and the exercise price of the
Warrants, the number of shares of Class A Common Stock potentially issuable
cannot be determined, potentially resulting in substantial dilution to the
ownership interest of existing holders of Class A Common Stock. This dilution
will be in addition to the dilution resulting from the issuance and sale of
shares of Class A Common Stock under the Equity Line Agreement. Approval of this
proposal will increase the potential for dilution of the ownership interests of
existing holders of Class A Common Stock.
 
     Resale of Shares. The Company has granted registration rights to the
holders of (i) the shares of Class A Common Stock issuable upon the conversion
of the Series D Preferred Stock and the exercise of the Warrants and (ii) shares
of Class A Common Stock pursuant to the Equity Line Agreement. Consequently, a
large number of shares of Class A Common Stock is likely to become freely
tradeable without restriction under the Securities Act of 1933. Such sales could
materially and adversely affect the market price of the Class A Common Stock.
 
RECOMMENDATION
 
   
     The affirmative vote of the holders of a majority of the Shares of the
Company present in person or represented by proxy at the Meeting and voted is
required for the approval of the foregoing proposal. THE BOARD OF DIRECTORS
UNANIMOUSLY RECOMMENDS A VOTE "FOR" THE APPROVAL OF THE ISSUANCE OF MORE THAN
20% OF THE OUTSTANDING SHARES OF CLASS A COMMON STOCK.
    
 
                                 OTHER BUSINESS
 
     The Company knows of no other matters to be submitted at the Meeting. If
any other matters are properly brought before the Meeting or any adjournment
thereof, it is the intention of the persons named in the enclosed proxy to vote
the Shares that they represent in accordance with their judgment.
 
     We urge you as a Shareholder to complete, date, sign and promptly return
the enclosed proxy card.
 
                                          By Order of the Board of Directors
                                          /s/ Gregory P. Hanson
                                          GREGORY P. HANSON
                                          Secretary
 
San Diego, California
 
                                        8
<PAGE>   12
 
                                  ATTACHMENT A
 
         SUMMARY DESCRIPTION OF THE PREFERRED STOCK AGREEMENT, SERIES D
          PREFERRED STOCK, THE WARRANTS AND THE EQUITY LINE AGREEMENT
 
     The following summary is qualified in its entirety by the terms and
provisions of the final versions of the Preferred Stock Agreement, the Equity
Line Agreement and related agreements, copies of which the Company has filed
with the SEC.
 
DESCRIPTION OF THE PREFERRED STOCK AGREEMENT
 
     Pursuant to the Preferred Stock Agreement, the Company may sell up to 500
shares of the Series D Preferred Stock (and related Warrants) at a price per
share of $10,000 for an aggregate purchase price of up to $5,000,000. A summary
description of the offering of Series D Preferred Stock to the Series D
Investors follows:
 
     - At the initial closing, the Company sold and issued 200 shares of Series
       D Preferred Stock to the Series D Investors for an aggregate purchase
       price of $2,000,000.
 
     - Subject to the Company's satisfaction of various closing conditions, the
       Series D Investors will be required to purchase (i) 100 additional shares
       of Series D Preferred Stock for the aggregate purchase price of
       $1,000,000 under the same terms and conditions as the initial closing
       (revised to reflect the Company's then current market price of its Class
       A Common Stock) and (ii) an equal number of related Warrants. These
       conditions include, among other things, shareholder approval for the
       issuance of more than 20% of the outstanding shares of Class A Common
       Stock pursuant to conversion of the shares of Series D Preferred Stock.
 
     - Subject to the Company's satisfaction of various closing conditions, the
       Series D Investors will have the right to purchase up to 200 additional
       shares of Series D Preferred Stock and an equal number of related
       Warrants for the aggregate purchase price of $2,000,000.
 
DESCRIPTION OF SERIES D PREFERRED STOCK
 
     Conversion Price. The Company's Board of Directors has designated 500
shares of the Company's 10,000,000 authorized shares of Preferred Stock as
Series D Preferred Stock. The Series D Investors may convert any or all of the
shares of Series D Preferred Stock that they acquire into fully paid and
nonassessable shares of Class A Common Stock at a conversion rate equal to
$10,000 divided by a conversion price equal to the lesser of (i) the Fixed
Conversion Price (as defined below) or (ii) the Variable Conversion Price (as
defined below). The "Fixed Conversion Price" is equal to (a) $1.05 per share of
Class A Common Stock during the first 120 calendar days following the initial
closing, and (b) thereafter, 120% of the five-day average of the closing bid
prices per share of the Class A Common Stock during the five (5) trading days
immediately preceding the 121st calendar day after the initial closing (subject
to adjustment if the Company does not secure a line of credit for at least
$2,000,000 within 110 days after the initial closing). The "Variable Conversion
Price" is equal to (x) 100% of the Market Price (as defined below) during the
first 75 calendar days following the initial closing for shares of Class A
Common Stock and (y) thereafter, 86% of the Market Price. "Market Price" is
defined as the lower of (i) the average of the five lowest closing bid prices
per share of Class A Common Stock on the Nasdaq National Market System during
the 25 trading days immediately preceding a given date of determination (ii) or
the closing bid price per share of Class A Common Stock on the Nasdaq National
Market System on the date of determination.
 
     Dividend Rate and Voting Rights. A cumulative dividend of 5% per annum is
payable either quarterly in cash or upon conversion in shares of Class A Common
Stock, at the Company's option. Holders of Series D Preferred Stock shall have
no voting rights, except as required by law, and as expressly provided in the
Certificate of Determination for Series D Preferred Stock. In particular, the
rights of the shares of Class A Common Stock shall be subject to the preferences
and relative rights of the shares of Series D Preferred Stock. In addition, the
Company will require the prior express written consent of the holders of not
less than two-thirds of the then outstanding shares of Series D Preferred Stock
to effect certain transactions, including
                                       A-1
<PAGE>   13
 
(i) the authorization or issuance of additional or other capital stock that is
of rank senior to or equal in status to the Series D Preferred Stock and (ii)
any amendment to the Company's Articles of Incorporation or By-laws which would
impair the rights or relative priority of the holders of Series D Preferred
Stock relative to the holders of the Class A Common Stock or the holders of any
other class of capital stock. Furthermore, in the event of the merger or
consolidation of the Company with or into another corporation, the shares of
Series D Preferred Stock shall maintain their relative powers, designations and
preferences provided for in the Certificate of Determination.
 
     Automatic Conversion. Any shares of Series D Preferred Stock still
outstanding five years from issuance automatically convert into Class A Common
Stock at the then applicable conversion price.
 
     Company's Right to Force Conversion. Immediately following at least (i) 90
consecutive calendar days of effectiveness of the registration statement
(described below) and (ii) 30 consecutive trading days during which the
Company's Class A Common Stock closes at 200% of the Fixed Conversion Price in
effect at the beginning of such 30-day period, the Company may elect to deliver
a notice of conversion to the Series D Investors ("Forced Conversion Notice").
Upon receipt of a Forced Conversion Notice, a Series D Investor is required to
convert the shares of Series D Preferred Stock held by such Series D Investor
and specified within such Forced Conversion Notice within 30 to 40 trading days
immediately following receipt of such Forced Conversion Notice ("Forced
Conversion Period"). The notice will be null and void under certain conditions,
including if at any time during the Forced Conversion Period either (i) the
Company's Class A Common Stock is suspended from trading, (ii) the effectiveness
of the registration statement is suspended or (iii) the closing bid price of the
Company's Class A Common Stock during each day of the Forced Conversion Period
is less than 85% of the closing bid price on the trading day immediately
preceding receipt of the Forced Conversion Notice.
 
     Company's Options to Redeem. Upon at least 30 trading days written notice,
the Company may elect to redeem, on the date which is the third anniversary of
effectiveness of the registration statement, all of the outstanding shares of
Series D Preferred Stock at a price per share equal to 120% of the purchase
price ($10,000) plus accrued but unpaid dividends, if any. In addition, the
Company may make a redemption election stating that, if any shares of Series D
Preferred Stock are presented for conversion during the thirty calendar days
beginning on the fifth business day following receipt of such notice by the
Series D Investors at a conversion price which is less than $1.00 per share,
then the Company intends to redeem those shares of Series D Preferred Stock at a
price per share equal to the product of (x) the number of shares otherwise
issuable upon conversion of each share of Series D Preferred Stock and (y) the
closing market price of the Class A Common Stock on the day such shares of
Series D Preferred Stock are presented for conversion. The Company may specify
that it will redeem up to a certain dollar amount of conversions, while allowing
conversions on the remaining portion. The Company may terminate the redemption
period anytime by delivering to the Series D Investors a termination notice. If
the Company fails to complete a redemption pursuant to its giving notice of its
intent to redeem shares of Series D Preferred Stock, then the Company will need
to seek Series D Investor consent prior to delivering any additional notices of
intent to redeem shares of Series D Preferred Stock.
 
     Registration Rights. The Company has agreed to file a registration
statement covering the shares of Class A Common Stock underlying the shares of
Series D Preferred Stock within 45 days of the initial closing and use its best
efforts to cause such registration statement to become effective as soon as
practicable. If such registration statement has not been declared effective by
the 75th calendar day following the initial closing, both the Fixed Conversion
Price and the Variable Conversion Price would be reduced by 1.5%, and would be
reduced further by an additional 0.05% for each calendar day thereafter until
such registration statement became effective and the Series D Investors can sell
under the registration statement.
 
DESCRIPTION OF THE WARRANTS.
 
     Each five-year Warrant is exercisable into 500 shares of Class A Common
Stock. The exercise price of the Warrants is equal to (i) $1.05 per share of
Class A Common Stock during the first 120 calendar days, and (ii) thereafter,
120% of the five-day average of the closing bid prices of the Class A Common
Stock
 
                                       A-2
<PAGE>   14
 
immediately preceding the 121st calendar day after the initial closing (subject
to adjustment in the event that the Company does not secure a line of credit for
at least $2,000,000 within the first 110 days after the initial closing).
 
DESCRIPTION OF EQUITY LINE AGREEMENT
 
     Up to $13,000,000 in shares of Class A Common Stock ($10,000,000 at the
option of the Company and $3,000,000 at the option of the Equity Line Investor)
can be issued under the terms and conditions of the Equity Line Agreement.
 
     Term. The Equity Line Agreement automatically terminates upon the earlier
of (i) when the Equity Line Investor has purchased an aggregate of $10,000,000
in shares of Class A Common Stock (excluding the $3,000,000 option of the Equity
Line Investor), (ii) on the date that is 24 months after the effective date of
the related registration statement, or (iii) the date that is 30 months after
January 22, 1999, the date of the Equity Line Agreement.
 
     Company Right to Put Stock. At any time during effectiveness of the
registration statement described below, the Company may deliver put notice(s) to
the Equity Line Investor which specify a minimum dollar amount of Class A Common
Stock that the Company requires the Equity Line Investor to purchase within the
next 25 business days following receipt of such put notice ("Purchase Period").
Put notice(s) generally can be reactivated every 30 business days. The market
price of Class A Common Stock must be equal to or greater than $1.00 when the
Company delivers put notices(s) to the Equity Line Investor.
 
     Purchase Amount Upon Put and Other Terms. Upon receipt of a put notice, the
Equity Line Investor is required to purchase the dollar amount of Class A Common
Stock equal to the lesser of (i) a minimum dollar amount determined by the
Company (the "Minimum Dollar Amount"); (ii) $1,000,000; and (iii) 12% of the
applicable dollar value of the Company's Class A Common Stock traded during the
20 trading days following receipt of such put notice (in either case, the
"Investor Obligation Amount" during each Purchase Period.) The Company has an
option to elect, in connection with each put notice, a minimum purchase price
per share of Class A Common Stock ("Minimum Purchase Price"). The price per
share at which the Equity Line Investor must purchase shares ("Purchase Price")
equals the greater of (i) 94% of the lowest daily dollar volume-weighted average
price of the Class A Common Stock during the six business days including and
immediately preceding the date of delivery of each respective Purchase Notice or
(ii) the Minimum Purchase Price. The Equity Line Investor must purchase at least
the Investor Obligation Amount by the end of the applicable Purchase Period.
During the first 12 months of the Equity Line Agreement, the Company is required
to deliver a number of put notices such that the Equity Line Investor is caused
to purchase an Investor Obligation Amount of $2,500,000. If the Company fails to
do so, then the Company must immediately pay the Equity Line Investor $150,000
in cash. Upon execution of the Equity Line Agreement, the Company paid to the
Equity Line Investor $100,000 in cash. The Company also will provide the Equity
Line Investor with an additional $150,000 in the aggregate, payable either in
cash or unrestricted shares of the Class A Common Stock, depending on whether
the related registration statement is filed on or before August 15, 1999 and
whether the SEC declares such registration statement effective on or before 45
days or 75 days after the filing date of such registration statement.
 
     Registration Rights. The Company has agreed to file a registration
statement for the shares of the Class A Common Stock to be purchased by the
Equity Line Investor on or prior to August 15, 1999, provided however, that the
Company cannot file the registration statement within 45 days after the
registration statement for the Series D Preferred Stock transaction has been
declared effective.
 
                                       A-3
<PAGE>   15
                             AVANIR PHARMACEUTICALS

                       9393 Towne Centre Drive, Suite 200
                        San Diego, California 92121-3016

           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS


   
        The undersigned hereby constitutes and appoints Gerald J. Yakatan and
Gregory P. Hanson, and each of them, his true and lawful agents and proxies with
full power of substitution in each, to represent the undersigned at the Special
Meeting of Shareholders of AVANIR Pharmaceuticals to be held at the Company's
offices at 9393 Towne Centre Drive, Suite 200, San Diego, California 92121, on
May 11, 1999, at 11:00 a.m., local time, and at any adjournments thereof, and to
vote as designated.
    


THIS PROXY WHEN PROPERLY EXECUTED WILL BE VOTED IN THE MANNER DIRECTED HEREIN BY
THE UNDERSIGNED SHAREHOLDER. IF NO DIRECTION IS MADE, THIS PROXY WILL BE VOTED
"FOR" THE ISSUANCE OF MORE THAN 20% OF THE OUTSTANDING SHARES OF COMMON STOCK.


PLEASE MARK, SIGN, DATE AND RETURN THIS PROXY CARD PROMPTLY USING THE ENCLOSED
ENVELOPE.


                      YOUR VOTE IS IMPORTANT! PLEASE VOTE.

                           (Continued on reverse side)



                                      B-1


<PAGE>   16
                                  BACK OF CARD

- --------------------------------------------------------------------------------

THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" APPROVAL OF THE FOLLOWING
PROPOSAL:


1.      TO APPROVE THE ISSUANCE OF MORE THAN 20% OF THE OUTSTANDING SHARES OF
        COMMON STOCK

- --------------------------------------------------------------------------------
        Vote For ____           Vote Against ____             Abstain ____
- --------------------------------------------------------------------------------

2.      AND TO VOTE ON SUCH OTHER BUSINESS AS MAY PROPERLY COME BEFORE THE
        MEETING

                                    Dated:                                , 1999

                                    Signature of Shareholder(s)

                                    Signature of Shareholder(s)

                                    Please sign exactly as name appears hereon.
                                    When shares are held by joint tenants, both
                                    should sign. When signing as attorney,
                                    executor, administrator, trustee or
                                    guardian, please give full title as such. If
                                    a corporation, please sign in full corporate
                                    name by president or other authorized
                                    officer. If a partnership, please sign in
                                    partnership name by authorized person.

THANK YOU FOR VOTING



                                      B-2


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