CHEMICALS & MATERIALS ENTERPRISE ASSOCIATES L P
SC 13G/A, 1999-02-16
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                               UNITED STATES                    
                      SECURITIES AND EXCHANGE COMMISSION           
                          Washington, D.C. 20549                 
                                                   
                               SCHEDULE 13G                     
                                                   
                   Under the Securities Exchange Act of 1934      
                            (Amendment No. 2)*                  

                            Physiometrix, Inc.
- --------------------------------------------------------------------------------
                              (Name of Issuer)

                        Common Stock, $.001 par value
- --------------------------------------------------------------------------------
                       (Title of Class of Securities)

                                 718928104
                     ----------------------------------
                              (CUSIP Number)

                              December 31, 1998
- --------------------------------------------------------------------------------
               (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this 
Schedule is filed:

     / / Rule 13d-1(b)

     / / Rule 13d-1(c)

     /X/ Rule 13d-1(d)

   *The remainder of this cover page shall be filled out for a reporting 
person's initial filing on this form with respect to the subject class of 
securities, and for any subsequent amendment containing information which 
would alter the disclosures provided in a prior cover page.

   The information required in the remainder of this cover page shall not 
be deemed to be "filed" for the purpose of Section 18 of the Securities 
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that 
section of the Act but shall be subject to all other provisions of the Act 
(however, see the Notes).

                              Page 1 of 10 pages

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ITEM 1(a).  NAME OF ISSUER. Physiometrix, Inc.

ITEM 1(b).  ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 
            5 Billerica Park, 101 Billerica Avenue, North Billerica, MA 01862.

ITEM 2(a).  NAMES OF PERSONS FILING: Chemicals and Materials Enterprise 
            Associates, Limited Partnership ("CMEA"), NEA Chemicals and 
            Materials Partners, Limited Partnership ("CMEA Partners"), which 
            is a general partner of CMEA, Cornelius C. Bond, Jr. ("Bond"), 
            Nancy L. Dorman ("Dorman"), C. Richard Kramlich ("Kramlich"), 
            Arthur J. Marks ("Marks"), Thomas C. McConnell ("McConnell") and 
            Charles W. Newhall III ("Newhall") (the "General Partners"), and 
            Thomas R. Baruch ("Baruch") and Donald L. Murfin ("Murfin"). The 
            General Partners are individual general partners of CMEA 
            Partners. Baruch and Murfin are individual general partners of 
            CMEA. The persons named in this paragraph are referred to 
            individually herein as a "Reporting Person" and collectively as 
            the "Reporting Persons."

ITEM 2(b).  ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: The 
            address of the principal business office of CMEA Partners, 
            Dorman, Marks, Murfin and Newhall is New Enterprise Associates, 
            1119 St. Paul Street, Baltimore, Maryland 21202. The address of 
            the principal business office of Bond, Kramlich and McConnell is 
            New Enterprise Associates, 2490 Sand Hill Road, Menlo Park, 
            California 94025. The address of the principal business office of 
            CMEA and Baruch is 235 Montgomery Street, Suite 920, San 
            Francisco, CA 94104.

ITEM 4.     OWNERSHIP.

            (a) Amount Beneficially Owned: CMEA is the record owner of 
                631,190 shares of Common Stock as of December 31, 1998 (the 
                "CMEA Shares"). As a general partner of CMEA, CMEA Partners 
                may be deemed to own beneficially the CMEA Shares. As a 
                general partner of CMEA, Murfin may be deemed to own 
                beneficially the CMEA Shares. As individual general partners 
                of CMEA Partners, which is a general partner of CMEA, Bond, 
                Dorman, Kramlich, Marks, McConnell and Newhall may be deemed 
                to own beneficially the CMEA Shares. Baruch is the record 
                owner of options to purchase 23,542 shares, which options 
                will be exercisable within 60 days of December 31, 1998. As a 
                general partner of CMEA, Baruch may be deemed to own 
                beneficially the CMEA Shares and the 23,542 shares for a 
                total of 654,732 shares.

            (b) Percent of Class: Each Reporting Person except Baruch: 11.1%. 
                Baruch: 11.5% The foregoing percentages are calculated based 
                on the 9,613,937 shares of Common Stock reported to be 
                outstanding in the Quarterly Report on Form 10-Q of 
                Physiometrix, Inc. for the quarter ended September 30, 1998, 
                as adjusted pursuant to Rule 13d-3(d)(1).

            (c) Number of shares as to which such person has:

                (i) sole power to vote or to direct the vote: 0 shares for 
                    each Reporting Person other than Baruch. 23,542 shares 
                    for Baruch.

                              Page 2 of 10 pages

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               (ii) shared power to vote or to direct the vote: 631,190 
                    shares for each Reporting Person other than Baruch. 
                    654,732 shares for Baruch.

              (iii) sole power to dispose or to direct the disposition of: 
                    0 shares for each Reporting Person other than Baruch. 
                    23,542 shares for Baruch.

               (iv) shared power to dispose or to direct the disposition of: 
                    631,190 shares for each Reporting Person other than 
                    Baruch. 654,732 shares for Baruch.

            Each Reporting Person disclaims beneficial ownership of any shares
            of Common Stock of Physiometrix, Inc., except for those shares, if 
            any, such Reporting Person holds of record.

ITEM 5.     OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.

            Not applicable.

ALL OTHER ITEMS REPORTED ON THE SCHEDULE 13G DATED AS OF FEBRUARY 10, 1998 
AND FILED ON BEHALF OF THE REPORTING PERSONS WITH RESPECT TO THE COMMON STOCK 
OF PHYSIOMETRIX, INC. REMAIN UNCHANGED.



                              Page 3 of 10 pages

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                                  SIGNATURE

    After reasonable inquiry and to the best of its knowledge and belief, each 
of the undersigned certifies that the information set forth in this statement 
is true, complete and correct.


Date: February 10, 1999

CHEMICALS AND MATERIALS ENTERPRISE ASSOCIATES, LIMITED PARTNERSHIP

By: NEA Chemicals and Materials Partners, Limited Partnership

By:                *
   -----------------------------------
   Charles W. Newhall III  
   General Partner         

NEA CHEMICALS AND MATERIALS PARTNERS, LIMITED PARTNERSHIP


By:                *
   ------------------------------------
   Charles W. Newhall III 
   General Partner        


                  *
- -------------------------------------
Cornelius C. Bond, Jr.


                  *
- -------------------------------------
C. Richard Kramlich


                  *
- -------------------------------------
Arthur J. Marks


                  *
- -------------------------------------
Thomas C. McConnell


                                    Page 4 of 10 pages



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                  *
- -------------------------------------
Charles W. Newhall III



                                      */s/ Nancy L. Dorman
                                      -----------------------------------------
                                      Nancy L. Dorman
                                      on her own behalf and as Attorney-in Fact


- -------------------------------------------------------------------------------
*This Schedule 13G was executed by Nancy L. Dorman pursuant to a Power of 
Attorney filed with the Securities and Exchange Commission on February 13, 
1992 in connection with a Schedule 13G for Advanced Interventional Systems 
Inc., which Power of Attorney is incorporated herein by reference and is 
attached hereto as Exhibit 2.


                             Page 5 of 10 pages

<PAGE>

                                                                     EXHIBIT 1


                                 AGREEMENT

    Pursuant to Rule 13d-1(f)(1) under the Securities Exchange Act of 1934, 
the undersigned hereby agree that only one statement containing the 
information required by Schedule 13G need be filed with respect to the 
ownership by each of the undersigned of shares of Common Stock of 
Physiometrix, Inc.

    EXECUTED as a sealed instrument this 10th day of February, 1999.

CHEMICALS AND MATERIALS ENTERPRISE ASSOCIATES, LIMITED PARTNERSHIP

By:  NEA Chemicals and Materials Partners, Limited Partnership

     By:           *
        -------------------------------
         Charles W. Newhall III
         General Partner       


NEA CHEMICALS AND MATERIALS PARTNERS, LIMITED PARTNERSHIP


By:                *
   ------------------------------------
   Charles W. Newhall III 
   General Partner        


                  *
- -------------------------------------
Cornelius C. Bond, Jr.


                  *
- -------------------------------------
C. Richard Kramlich


                  *
- -------------------------------------
Arthur J. Marks


                  *
- -------------------------------------
Thomas C. McConnell


                             Page 6 of 10 pages


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                  *
- -------------------------------------
Charles W. Newhall III



                                      */s/ NANCY L. DORMAN
                                      -------------------------------
                                      Nancy L. Dorman
                                      on her own behalf and as Attorney-in Fact


- -------------------------------------------------------------------------------
*This Agreement was executed by Nancy L. Dorman pursuant to a Power of 
Attorney filed with the Securities and Exchange Commission on February 13, 
1992 in connection with a Schedule 13G for Advanced Interventional Systems 
Inc., which Power of Attorney is incorporated herein by reference and 
attached hereto as Exhibit 2.


                             Page 7 of 10 Pages




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                                                                      EXHIBIT 2


                             POWER OF ATTORNEY


    KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears 
below hereby constitutes and appoints Nancy L. Dorman and Charles W. Newhall 
III, and each of them, with full power to act without the other, his true and 
lawful attorney-in-fact, with full power of substitution, to sign any and 
all instruments, certificates and documents that may be necessary, desirable 
or appropriate to be executed on behalf of himself as an individual or in his 
capacity as a general partner of any partnership, pursuant to section 13 or 
16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), 
and any and all regulations promulgated thereunder, and to file the same, 
with all exhibits thereto, and any other documents in connection therewith, 
with the Securities and Exchange Commission, and with any other entity when 
and if such is mandated by the Exchange Act or by the By-laws of the National 
Association of Securities Dealers, Inc., granting unto said attorney-in-fact 
full power and authority to do and perform each and every act and thing 
necessary, desirable or appropriate, fully to all intents and purposes as 
he might or could do in person, thereby ratifying and confirming all that 
said attorney-in-fact, or his substitutes, may lawfully do or cause to be 
done by virtue hereof.

    IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 23rd 
day of April, 1991.


                                               /S/ RAYMOND L. BANK
                                               --------------------------------
                                               Raymond L. Bank


                                               /S/ THOMAS R. BARUCH
                                               --------------------------------
                                               Thomas R. Baruch


                                               /S/ CORNELIUS C. BOND, JR.
                                               --------------------------------
                                               Cornelius C. Bond, Jr.


                                               /S/ FRANK A. BONSAL, JR.
                                               --------------------------------
                                               Frank A. Bonsal, Jr.


                                               /S/ JAMES A. COLE
                                               --------------------------------
                                               James A. Cole



                             Page 8 of 10 pages



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                                               /S/ NANCY L. DORMAN
                                               --------------------------------
                                               Nancy L. Dorman


                                               /S/ NEAL M. DOUGLAS
                                               --------------------------------
                                               Neal M. Douglas


                                               /S/ JOHN W. GLYNN, JR.
                                               --------------------------------
                                               John W. Glynn, Jr.


                                               /S/ CURRAN W. HARVEY
                                               --------------------------------
                                               Curran W. Harvey


                                               /S/ RONALD KASE
                                               --------------------------------
                                               Ronald Kase


                                               /S/ C. RICHARD KRAMLICH
                                               --------------------------------
                                               C. Richard Kramlich


                                               /S/ ROBERT F. KUHLING
                                               --------------------------------
                                               Robert F. Kuhling


                                               /S/ ARTHUR J. MARKS
                                               --------------------------------
                                               Arthur J. Marks


                                               /S/ THOMAS C. MCCONNELL
                                               --------------------------------
                                               Thomas C. McConnell


                                               /S/ DONALD L. MURFIN
                                               --------------------------------
                                               Donald L. Murfin


                                               /S/ H. LELAND MURPHY
                                               --------------------------------
                                               H. Leland Murphy



                            Page 9 of 10 pages


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                                               /S/ JOHN M. NEHRA
                                               --------------------------------
                                               John M. Nehra


                                               /S/ CHARLES W. NEWHALL III
                                               --------------------------------
                                               Charles W. Newhall III


                                               /S/ TERRY L. OPDENDYK
                                               --------------------------------
                                               Terry L. Opdendyk


                                               /S/ BARBARA J. PERRIER
                                               --------------------------------
                                               Barbara J. Perrier


                                               /S/ C. VINCENT PROTHRO
                                               --------------------------------
                                               C. Vincent Prothro


                                               /S/ C. WOODROW REA, JR.
                                               --------------------------------
                                               C. Woodrow Rea, Jr.


                                               /S/ HOWARD D. WOLFE, JR.
                                               --------------------------------
                                               Howard D. Wolfe, Jr.


                                               /S/ NORA M. ZIETZ
                                               --------------------------------
                                               Nora M. Zietz


                             Page 10 of 10 pages




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