MEDICIS PHARMACEUTICAL CORP
10-K, 1996-08-15
PHARMACEUTICAL PREPARATIONS
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                                  United States
                       Securities and Exchange Commission
                             Washington, D.C. 20549

                     . . . . . . . . . . . . . . . . . . . .

                                    FORM 10-K

[X]      ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
                              EXCHANGE ACT OF 1934
                    For the fiscal year ended June 30, 1996.

                                       or

[]       TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
                              EXCHANGE ACT OF 1934
                 For the transition period from ____ to _____.

                         Commission file number 0-18443

                       MEDICIS PHARMACEUTICAL CORPORATION
           ----------------------------------------------------------
             (Exact name of registrant as specified in its charter)

        Delaware                                      52-1574808
- ---------------------------------         ------------------------------------
(State of other jurisdiction              (I.R.S. Employer Identification No.)
of incorporation or organization)

4343 East Camelback Road, Suite 250, Phoenix, AZ                    85018-2700
- -----------------------------------------------------------        ------------
        (Address of principal executive office)                      (Zip Code)

Registrant's telephone number, including area code:       (602)  808-8800

Securities registered pursuant to Section 12(b) of the Act:        NONE

<TABLE>
<S>                                                            <C>                                        <C> 
Securities registered pursuant to Section 12(g) of the Act:    Class A Common Stock, $.014 par value Preference Share
                                                               Purchase Rights
                                                               (Title of each Class)
</TABLE>

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the preceding 12 months (or for such shorter period that the registrant was
required to file such reports), and (2) has been subject to such filing
requirements for the past 90 days. Yes X   No
                                      ---    ---
Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of the registrant's knowledge, in definitive proxy or information
statements incorporated by reference in Part III of this Form or any amendment
to this Form 10-K [ ].

The aggregate market value on August 5, 1996, of the voting stock held on August
5, 1996, by non-affiliates of the registrant was $225,476,449 (calculated by
excluding all shares held by executive officers, directors and holders of five
percent or more of the voting power of the registrant's Common Stock, without
conceding that such persons are "affiliates" of the Registrant for purposes of
the federal securities law).

As of August 3, 1996 there were 6,832,633 shares of Class A Common Stock $0.014
par value, 125,322 shares of Class B Common Stock $0.014 par value, and 62,660
shares of Series B Preferred Stock, $0.01 par value outstanding.

Documents incorporated by reference:

     Portions of the Proxy Statement for the Registrant's 1996 Annual Meeting of
Stockholders are incorporated herein by reference in Part III of this Form 10-K
to the extent stated herein.

                                      
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                                     PART I

         This Report contains forward-looking statements which involve risks and
uncertainties. The actual results of Medicis Pharmaceutical Corporation
(together with its wholly-owned subsidiaries, the "Company" or "Medicis") could
differ materially from those anticipated in these forward-looking statements as
a result of certain factors, including those set forth in this Form 10-K and the
Company's other Securities and Exchange Commission filings. See Item 7,
Management's Discussion and Analysis of Financial Condition and Results of
Operations.

ITEM 1.           BUSINESS

THE COMPANY

         Medicis is the leading independent pharmaceutical company in the United
States that offers prescription and non-prescription (over-the-counter) 
products exclusively to treat dermatological conditions. Emphasizing the
clinical effectiveness, quality, affordability and cosmetic elegance of its
products, the Company has achieved a leading position in the treatment of acne
and acne-related conditions using prescription pharmaceuticals, while also
offering the leading domestic over-the-counter ("OTC") fade cream product. The
Company has built its business through the successful introduction of DYNACIN
and TRIAZ products for the treatment of acne and the acquisition of the
ESOTERICA fade cream product line.

PRINCIPAL PRODUCTS AND PRODUCT LINES

         Medicis currently offers products in the following areas of
dermatology: acne, hyperpigmentation, inflammatory skin diseases, dry skin and
cosmetic dermatology. The Company addresses these areas with a range of
prescription and OTC products.

     Prescription Pharmaceuticals

         Prescription pharmaceuticals accounted for 83.2% of the Company's net
sales in the fiscal year ended June 30, 1996 ("fiscal 1996"). Medicis currently
focuses its prescription pharmaceutical efforts primarily on treating acne and
related conditions. The Company's principal branded pharmaceuticals are as
follows:

DYNACIN is an oral, systemic antibiotic prescribed for the treatment of moderate
to severe acne vulgaris, the most common form of acne, a condition that resulted
in over 10 million visits to dermatologists in 1995. The most commonly
prescribed systemic acne treatments are tetracycline and its derivatives,
doxycycline and minocycline. Minocycline, the active ingredient in DYNACIN
products, is widely prescribed for the treatment of acne for several reasons. It
has a more convenient schedule of one or two doses per day as compared to other
forms of tetracycline, which can require up to four doses per day. Other forms
of tetracycline require ingestion on an empty stomach and often increase patient
sensitivity to sunlight, creating a greater risk of sunburn. Moreover, the other
forms of tetracycline, including doxycycline, often cause gastric irritation. In
addition, resistance to several commonly used antibiotics, including
erythromycin, clindamycin, doxycycline and tetracycline, by the primary
bacterial organism responsible for acne has been documented. Studies suggest
that bacterial resistance to erythromycin exceeds 60%, and resistance to
doxycycline and tetracycline exceeds 40%, while the bacteria showed virtually no
resistance to minocycline. Thus, although more expensive than other forms of
branded tetracycline and many times more expensive than generic tetracycline,
minocycline is documented to have clinical performance that is superior to other
forms of tetracycline, while avoiding many of its disadvantages. However,
DYNACIN's retail price is approximately 30% lower than the average reported
retail price of the other leading branded minocycline product, Minocin, while
selling at approximately 25% to 30% higher than the average reported retail
price of generic minocycline. DYNACIN is at least comparable in performance to
Minocin and is believed by the Company to enjoy certain performance
characteristics that favorably distinguish it from generic minocycline. DYNACIN
was launched in the second quarter of the fiscal year ended June 30, 1993
("fiscal 1993"). At June 30, 1996, DYNACIN products held approximately 51% of
total branded minocycline market sales and was the leading brand of branded
minocycline in the United States. There can be no assurance that DYNACIN will
not lose significant market share in the future, that it will remain a
competitive product, or that the Company will be able to compete successfully in
the acne treatment 

                                               
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market through the sale of DYNACIN or any other product. The Company has 
entered into a manufacturing and supply agreement with Schein Pharmaceuticals, 
Inc. ("Schein") for the supply of DYNACIN products. See "-- Manufacturing."

TRIAZ is a topical therapy prescribed for the treatment of all forms and varying
degrees of acne, and is available as a gel available in two concentrations and
as a cleanser. The combined domestic sales of topically applied prescription
acne products were in excess of $400 million in 1995. The most frequently
prescribed topical acne treatments include Cleocin-T, generic topical
clindamycin, and Benzamycin. While these therapies are generally effective,
TRIAZ offers advantages over each product, including improved stability, greater
convenience of use, reduced cost and fewer side effects. Benzamycin requires
refrigeration and mixing by a pharmacist and has a relatively short shelf life
of three months. TRIAZ comes in a ready-mixed gel that does not require
refrigeration and has a two-year shelf life. In addition, TRIAZ is aesthetically
pleasing and minimizes the extreme drying and scaling of skin often caused by
competing brands. The average reported retail price of TRIAZ is less than that
of either Cleocin-T or Benzamycin. In addition, bacterial resistance has been
demonstrated with both Cleocin-T and erythromycin, an active ingredient in
Benzamycin. TRIAZ products are manufactured using the active ingredient benzoyl
peroxide in a vehicle containing glycolic acid and zinc lactate. Benzoyl
peroxide is the most efficacious agent available for clearing the bacteria that
cause acne. Glycolic acid enhances the effectiveness of benzoyl peroxide by
exfoliating the outer layer of the skin (thereby providing direct access to the
bacteria), and zinc lactate acts to reduce the appearance of inflammation and
irritation often associated with acne. TRIAZ was developed internally by the
Company's formulation scientists and introduced in the second quarter of fiscal
1996. There can be no assurance that the Company will be able to successfully
market the TRIAZ product line or that the TRIAZ product line will achieve or
retain market acceptance. The Company has a patent application and has certain
licensed patent rights covering varying aspects of TRIAZ. TRIAZ products are
manufactured to the Company's specifications on a purchase order basis by Paco
Laboratories, Inc. See "-- Manufacturing," "-- Trademarks" and "-- Patents and
Proprietary Rights."

THERAMYCIN Z is a topical therapy available as a lotion prescribed for the
treatment of acne. THERAMYCIN Z is erythromycin in a solution containing zinc
acetate, which acts to reduce the appearance of inflammation and irritation
often associated with acne. THERAMYCIN Z competes with other topical acne
treatments, including Cleocin-T, Erycette, ATS, Emgel and other topical
antibiotics. The Company has an exclusive worldwide license to market this
product from a subsidiary of IVAX Corporation ("IVAX"). The Company purchases
THERAMYCIN Z from IVAX pursuant to a manufacturing and supply agreement. See "--
Manufacturing" and "-- Certain License and Royalty Agreements."

BENZASHAVE products are shave creams marketed by the Company as topical
therapies for the treatment of pseudofolliculitis barbae ("PFB") and acne
associated with shaving. PFB, commonly called "razor bumps," is a painful
irritation aggravated by shaving. This condition affects millions of men in the
United States, particularly African Americans and others with relatively coarse
facial hair. However, medical treatment is often not sought, as many men
afflicted with PFB grow facial hair to avoid shaving, or use a variety of
nonprescription shaving products which claim to alleviate the condition. The
Company believes that BENZASHAVE products are the only prescription shaving
products available for treatment of PFB and acne associated with shaving. There
can be no assurance that the Company will be able to successfully market
BENZASHAVE products or that BENZASHAVE will achieve or maintain market
acceptance. The Company entered into an exclusive worldwide license to market
BENZASHAVE with IVAX in the fiscal year ended June 30, 1991 ("fiscal 1991"),
which includes a license of patent rights relating to the use of benzoyl
peroxide in the treatment of PFB. The Company purchases BENZASHAVE pursuant to a
manufacturing and supply agreement. See "-- Manufacturing," "-- Certain License
and Royalty Agreements," "-- Trademarks" and "-- Patents and Proprietary
Rights."

     Over-The-Counter Products

         OTC pharmaceutical products accounted for 16.8% of the Company's net
sales dollars in fiscal 1996. Medicis markets a variety of OTC skin care
products to treat pigmentation, dry skin and certain inflammatory skin
conditions. The Company's principal OTC products are as follows:

ESOTERICA is a line of topical creams used to treat minor skin discoloration
problems such as age spots, uneven skin tones, dark patches, blotches and
freckles. ESOTERICA is the leading line of fade creams in the United States.

                                               
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ESOTERICA product line is in five formulations, consisting of four creams
containing various concentrations of the active ingredient hydroquinone and a
body lotion. Hydroquinone is the only agent proven to reduce
hyperpigmentation and the only product legally sold in the United States for
this purpose. Other OTC products used to treat minor skin discoloration include
Porcelana and AMBI, which are sold in a variety of creams, gels and lotions.
There can be no assurance that the Company will be able to successfully market
the ESOTERICA product line or that the ESOTERICA product line will
maintain market acceptance. The Company acquired the ESOTERICA product line from
SmithKline Beecham Consumer Healthcare L.P. ("SmithKline") in fiscal 1991, and
assumed the marketing of these products in the United States and Canada. The
Company's manufacturing agreement with SmithKline for ESOTERICA expires in March
31, 1997. See "-- Manufacturing."

THERAPLEX is a line of moisturizers that are used for the treatment of dry skin
or certain inflammatory skin conditions, such as are present in psoriasis,
eczema or ichthyosis. The THERAPLEX line consists of three products, THERAPLEX
EMOLLIENT, THERAPLEX CLEARLOTION and THERAPLEX HYDROLOTION, that combine high
molecular weight hydrocarbons, the active component of petrolatum, with certain
silicones. THERAPLEX moisturizers do not contain the normally greasy, sticky and
odoriferous petrolatum components found in competitive products. Skin care
products containing the patented ingredient present in THERAPLEX moisturizers
have been marketed by other companies under other tradenames for several years
in certain European countries, and more recently in Canada. THERAPLEX
moisturizers compete with a variety of other moisturizing products, including
Eucerin, Lubriderm and Keri-Lotion, as well as other mass marketed moisturizers.
The Company acquired a license to the patent underlying the THERAPLEX product
line in 1990. There can be no assurance that the Company will be able to
successfully market the THERAPLEX product line or that the THERAPLEX product
line will achieve or retain market acceptance. The Company has various
agreements for the manufacture of the THERAPLEX product line on a purchase order
basis and is obligated to pay certain royalties on its product sales. See "--
Manufacturing" and "-- Certain License and Royalty Agreements."

PRODUCTS IN DEVELOPMENT

         The Company has developed and obtained rights to certain dermatological
agents in various stages of development, and with potential applications,
ranging from line extensions to new products or reformulations of existing
products. Medicis' strategy involves the rapid evaluation and formulation of new
therapeutics by obtaining preclinical safety and efficacy data (when possible),
followed by rapid safety and efficacy testing in humans. While development
periods may vary, the Company generally selects products for development with
the objective of proceeding from formulation to product launch within a two-year
period. 

         Medicis directs the efforts of contract laboratory research facilities
to perform formulation and research work on active ingredients as well as direct
the third-party conduct of preclinical studies and clinical trials. All products
and technologies under development will require significant commitments of
personnel and financial resources. Several products will require extensive
clinical evaluation and premarketing clearance by the United States Food and
Drug Administrative ("FDA") and comparable agencies in other countries prior to
commercial sale. Certain of the products and technologies under development have
been licensed from third parties. The failure of the Company to meet its
obligations under one or more of these agreements could result in the
termination of the Company's rights under such agreements. In addition, the
Company regularly reevaluates its product development efforts. On the basis of
these reevaluations, the Company has in the past, and may in the future, abandon
development efforts for particular products. No assurance can be given that any
product or technology under development will result in the successful
introduction of any new product. Failure of the Company to introduce and market
new products, whether internally developed or acquired from third parties, could
have a material adverse effect on the Company's business, financial condition or
results of operation. See "--Government Regulation."  

         The Company's research and development costs for Company-sponsored and
unreimbursed co-sponsored pharmaceutical projects for fiscal 1996, fiscal 1995
and fiscal 1994 were $952,000, $770,000 and $1,572,000, respectively. The fiscal
1994 amount includes approximately $727,000 of research and development costs
relating to divested operations. The Company has in the past supplemented, and
may in the future supplement, its research and development efforts by entering
into additional research and development agreements with other pharmaceutical
companies in order to defray the cost of product development. There can be no
assurance that the Company will enter into research and development agreements
acceptable to the Company, or at all.

                                               
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<PAGE>   5
MARKETING AND SALES

     Prescription Pharmaceuticals

         The Company believes its marketing and sales organization is one of the
most productive in the dermatology sector. The marketing effort is focused on
assessing and meeting the needs of dermatologists. The Company's marketing and
sales team, consisting of 30 members at August 3, 1996, regularly calls on
dermatologists. Those dermatologists who are responsible for a relatively
higher volume of prescriptions are visited more frequently. The Company has
created an incentive program based on aggressive goals in market share growth,
and believes that its highest performing sales representatives are among the
best compensated in the industry. The Company believes that its most effective
promotion is achieved by cultivating a relationship of trust and confidence with
dermatologists themselves. Medicis also uses a variety of marketing tactics to
promote its products, including sampling, journal advertising, promotional
material, specialty publications, rebate coupons, product guarantees, a
leadership position in educational conferences and exposure of its products on
the Internet.

     OTC Products

         The Company's OTC products are promoted to retailers and wholesalers by
manufacturers' representatives who also support a substantial number of products
of other manufacturers. The Company also markets its OTC products through trade
promotions, radio advertising, couponing and consumer awareness programs.

WAREHOUSING AND DISTRIBUTION

         The Company utilizes an independent national warehousing corporation to
store and distribute its products from three central warehousing locations in
California, Kansas and Maryland. Upon the receipt of a purchase order through
electronic data input ("EDI"), phone mail or facsimile, the order is processed
into the Company's inventory systems, at which time an inventory picking sheet
is automatically placed via EDI to the most efficient warehouse location for
shipment usually within 24 hours to the customer placing the order. Upon
shipment, the warehouse sends back to the Company via EDI the necessary
information to automatically process the invoice in a timely manner. 

CUSTOMERS

         Medicis' customers include the nation's leading wholesale
pharmaceutical distributors, such as McKesson, Bergen Brunswig Drug Company
("Bergen Brunswig"), Cardinal Health Inc. ("Cardinal"), Foxmeyer Drug Company
("Foxmeyer"), Bindley Western Drug Company ("Bindley") and major drug chains.
During fiscal 1996, McKesson Drug Company ("McKesson"), Bergen Brunswig and
Cardinal, accounted for approximately 15.5%,12.2% and 11.8%, respectively, of
the Company's sales. For fiscal 1995, McKesson and Bergen accounted for
approximately 15.9% and 9.6%, respectively, of the Company's sales. For fiscal
1994, McKesson and Bergen Brunswig accounted for approximately 15.1% and 11.2%,
respectively, of the Company's sales. The distribution network for
pharmaceutical products has, in recent years, been subject to increasing
consolidation. As a result, a few large wholesale distributors control a
significant share of the market. In addition, the number of independent drug
stores and small chains has decreased as retail consolidation has occurred.
Further consolidation among wholesale distributors or retailers could result in
the combination or elimination of warehouses which may stimulate products
returns to the Company, cause a reduction in their inventory levels, or
otherwise result in reductions in purchases of the Company's products, any of
which could result in a material adverse impact upon the Company's business,
financial condition or results of operations. 

MANUFACTURING

         The Company currently contracts for all of its manufacturing needs and
is permitted to contract only with manufacturers that comply with FDA current
Good Manufacturing Practices ("cGMP") regulations and other applicable laws and
regulations. The Company typically does not enter into long-term manufacturing
contracts with third-party manufacturers. Whether or not such contracts exist,
there can be no assurance that the Company will be able to obtain adequate
supplies of such products in a timely fashion, or at all.

                                               
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         The Company's DYNACIN products are manufactured by Schein in compliance
with the Company's stringent, internally developed specifications and quality
standards pursuant to a supply agreement that expires in December 1997. Under
the agreement, Schein manufactures minocycline for sale in the branded market
exclusively for the Company, but may manufacture and sell minocycline for
itself or others as a generic product. Schein currently manufactures minocycline
for the generic market under its own label. The Schein supply agreement is
subject to automatic renewal for successive two-year periods if neither party
gives timely notice of termination and may also be canceled without cause upon
12-months notice. Schein may also terminate the exclusivity portion of the
agreement if its profit margin on sales of DYNACIN products fall below a
specified level. Schein may terminate the agreement upon a material breach by
the Company, in the event that the Company becomes insolvent, or if any lawsuit
is commenced alleging a patent or a proprietary rights violation. The agreement
also provides that the Company will purchase all of its requirements for
minocycline from Schein but may purchase some of its requirements from another
manufacturer if Schein fails to meet certain cost standards or fails to provide
the Company with all of its requirements for two of four consecutive calendar
quarters. In addition, the Company may use alternative sources if Schein
terminates the Company's exclusive rights to purchase branded minocycline based
upon the Company's failure to meet the specified profit margins, as defined.
Either party may terminate the agreement in the event that one party cannot
perform under the agreement for a period of three months or longer for certain
reasons beyond its control, such as war, strike, fire, lockout or acts of God.
The Company believes that it has alternative sources of supply and that it would
be able to use these alternative sources to preserve an adequate supply of
DYNACIN. However, the inability of Schein to fulfill the Company's supply
requirements for DYNACIN, the Company's largest-selling product, could have a
material adverse effect on the Company's business, financial condition or
results of operations.

         The Company's ESOTERICA line of products are manufactured by SmithKline
pursuant to a manufacturing and supply agreement which expires in March 1997.
SmithKline may terminate its agreement in the event of a material breach by the
Company upon 15-days written notice. The Company's Canadian distributor
currently utilized Contract Manufacturing Associates to manufacture its
requirements of ESOTERICA for the Canadian market. In the event the Company or
SmithKline declines to renew such manufacturing and supply agreement, the
Company may utilize Contract Manufacturing Associates for its domestic product
requirements or such other manufacturer as it determines appropriate.

         The Company purchases THERAMYCIN Z and BENZASHAVE products 
exclusively from IVAX, pursuant to a manufacturing agreement expiring in July
2000. In the event that IVAX is prevented from completing performance of its
obligations under the Agreement for specified reasons beyond its control, it is
excused from such performance until such time as the event preventing its
performance ceases. If IVAX is unable to supply the Company's requirements of
either product, the Company is permitted to purchase the unsatisfied
requirements from third parties. The remainder of the Company's products are
produced on a purchase order basis only, including its THERAPLEX EMOLLIENT
products, manufactured by ViFor, S.A., a Swiss manufacturing company ("ViFor");
THERAPLEX CLEARLOTION products, manufactured by Accupac, Inc.; THERAPLEX
HYDROLOTION products, manufactured by Beauty Control Cosmetics, Inc.; TRIAZ
products, manufactured by Paco Laboratories, Inc. and THERAMYCIN Z and
BENZASHAVE products, which are manufactured by IVAX.

         There can be no assurance that the above manufacturers will continue to
meet the FDA's regulations or the Company's product specifications and standards
for the indicated products or that they can continue to meet product demand on a
consistent and timely basis. Schein, IVAX and ViFor are currently the sole
manufacturers of DYNACIN products, THERAMYCIN Z and BENZASHAVE products, and
THERAPLEX EMOLLIENT products, respectively. The Company believes that
alternative sources of manufacturing are available for all of its products.
Because of the FDA requirement for cGMP validation of manufacturing facilities
for particular products, validation of a new facility to serve as a replacement
source of manufacturing requires a substantial period of time. Any loss of a
manufacturer or other manufacturing difficulties could have a material adverse
effect on the Company's business, financial condition or results of operations.
The Company has obtained business interruption insurance to insure against the
loss of income for up to 12 months due to the interruption of manufacturing of
the Company's three principal products due to certain causes. While the Company
believes that the policy provides substantial protection against the covered
events, there can be no assurance that the policy will cover all manufacturing
interruptions or that the amount of such insurance will be adequate to fully
protect the Company for losses associated with such interruptions.

         The Company's third-party manufacturers rely on certain suppliers of
key raw materials. Certain of those materials are purchased from single sources
and others may be purchased from single sources in the future. Although the
Company has no reason to believe that it will be unable to procure adequate
supplies of such raw materials on a timely basis, 


                                               
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disruptions in supplies, including delays due to the inability of the Company or
its manufacturers to procure raw materials, would have a material adverse effect
on the Company's business, financial condition and results of operations.

         Any interruptions in the supply of any of the Company's products due to
shortages in raw materials, changes in manufacturing sources, regulatory changes
or other causes could delay or eliminate the Company's ability to supply such
products. In addition, the Company faces the risk that, upon expiration of the
term of any third-party manufacturing agreement, it may not be able to renew or
extend the agreement with the third-party manufacturer, to obtain an alternative
manufacturing source from other third parties or to develop internal
manufacturing capabilities on commercially viable terms, if at all. To manage
its resources effectively, the Company attempts to retain inventory levels that
are no greater than necessary to meet the currently projected needs of its
customers.

         Manufacture of the Company's THERAMYCIN Z and BENZASHAVE products was
suspended in fiscal 1994 following the acquisition by IVAX of certain assets of
Syosset, the original manufacturer of those products under the agreement, in
Syosset's bankruptcy proceeding. Manufacture of the BENZASHAVE products was
subsequently resumed, and the Company resumed shipping these products during
fiscal year ended June 30, 1995 (fiscal 1995"). During the second quarter of
fiscal 1996, manufacturing of the THERAMYCIN Z product also resumed. This
suspension did not have a material adverse effect on the Company's results of
operations. However, there can be no assurance that the Company will not suffer
future supply insufficiencies or interruptions or that it will be able to obtain
adequate supplies of its products in a timely fashion, or at all. While the
Company believes that its inventory levels are generally adequate, the loss of a
manufacturer, the failure to obtain a replacement manufacturer on a timely
basis, other manufacturing problems or any interruption of supply could have a
material adverse effect on the Company's business, financial condition or
results of operations.

CERTAIN LICENSE AND ROYALTY AGREEMENTS

         In July 1990, the Company entered into two separate license agreements
with IVAX, as successor to Syosset Laboratories, Inc. ("Syosset"), under which
the Company acquired a 10-year exclusive, worldwide license to market and
sublicense the products Erythromycin 2%, which Medicis markets as THERAMYCIN Z,
BENZASHAVE 5% and 10% and certain other products. IVAX also manufactures the
licensed products for the Company pursuant to a manufacturing agreement. The
licensing agreements are subject to termination by IVAX upon a material failure
of the Company to perform its obligations under the agreements for 60 days, or
upon the Company's failure to perform under the payment provisions of the
agreements for 30 days, or upon the filing of a petition in bankruptcy by or
against the Company.

         In April 1989, the Company sublicensed a United States patent relating
to the THERAPLEX line of products pursuant to a modified license agreement among
the Company, Dr. Hans Rudi Seuss and H.R. Seuss, A.G. (collectively, "Seuss")
and Euromerican Trade Resources, Inc. ("Euromerican"). The Company was granted
an exclusive sublicense to market all products manufactured pursuant to the
patent in the United States, Mexico and Japan, until the patent expires in
October 1999. The agreement further grants the Company the right to otherwise
exploit the know-how embodied in the patent. The agreement requires that the
Company make annual payments of specified minimum royalties. The agreement is
subject to termination by Seuss upon Euromerican's failure to perform its
obligations under the agreement for 45 days or by Seuss or Euromerican upon the
Company's failure to perform its obligations under the agreement for 45 days or
upon the occurrence of other standard events of default. The Company has also
received a separate assignment from Dr. Gars and Dr. Suess of certain patent
rights relating to the Company's THERAPLEX HYDROLOTION products.

         There can be no assurance that the Company will fulfill its obligations
under any of the foregoing agreements. The failure to satisfy the requirements
of any agreement could result in the loss of the Company's rights under the
agreements and in other related agreements which could have a material adverse
affect upon the Company's business, financial condition or results of
operations.

TRADEMARKS

         The Company believes that trademark protection is significant in
establishing product recognition. The Company owns 15 federally registered
trademarks. The Company has filed United States applications for registration of
seven additional trademarks and servicemarks. United States federal
registrations for trademarks remain in force for 10 years and may be renewed
every 10 years after issuance provided the mark is still being used in commerce.
There 


                                               
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<PAGE>   8
can be no assurance that any such trademarks or servicemarks will afford the
Company adequate protection, or that the Company will have the financial
resources to enforce its rights under any such trademarks and servicemarks. The
inability of the Company to protect its trademarks or servicemarks from
infringement could result in injury to any goodwill which may be developed in
such trademarks or servicemarks. Moreover, the Company's inability to use one or
more of its trademarks or servicemarks because of successful third-party claims
to such marks could have a material adverse effect on the Company's business,
financial condition or results of operations.

         An opposition to registration of the mark "THERAMYCIN Z" has been filed
and is currently pending in the United States Patent and Trademark Office. While
there can be no assurance as to the outcome of this matter, the Company does not
currently foresee any significant costs or loss of sales associated with the
reintroduction of THERAMYCIN Z under a different trade name.

     From time to time, the Company receives communications from parties who
allege that their trademark interests may be damaged either by the Company's use
of a particular trademark or its registration of such trademark. In general, the
Company seeks to resolve such conflicts before an actual opposition to
registration or suit for infringement is filed. There can, however, be no
assurance that such oppositions will not be filed or that, if filed, they will
not have a material adverse effect upon the Company's business, financial
condition or results of operations.

PATENTS AND PROPRIETARY RIGHTS

         The Company has licensed rights to products covered by certain United
States patents directed to aspects of the THERAPLEX and BENZASHAVE
compounds/formulations, and the Company has obtained patents directed to aspects
of several other compounds. The Company is also pursuing several United States
patent applications. No assurance can be given that patents will be issued with
respect to any of these applications. The Company has acquired rights under
certain patents and patent applications from third-party licensors. The Company
has also acquired from certain of its consultants and principals an assignment
of their rights to certain United States patents or patent applications. Certain
of such patents and patent applications may be subject to claims of rights by
third parties by reason of existing relationships with the party who filed such
patents or patent applications. No assurance can be given that the Company will
be able to obtain any rights under such patents or patent applications, as a
result of such conflicting claims, or that any rights which the Company may
obtain will be sufficient for the Company to market products which may be the
subject of such patents or patent applications. The Company may be required to
obtain licenses and or pay royalties to obtain the rights it acquires under such
patents or patent applications and no assurance can be given that the Company
will be able to obtain rights under such patents or patent applications on terms
acceptable to the Company, or at all.

         The Company believes that its success will depend in part on its
ability to obtain and maintain patent protection for its own inventions, and to
obtain and maintain licenses for the use of patents licensed or sublicensed by
third parties. No assurance can be given that any patent issued to, or licensed
by, the Company will provide protection that has commercial significance. In
this regard, the patent position of pharmaceutical compounds is particularly
uncertain. There can be no assurance that challenges will be not be instituted
against the validity or enforceability of any patent owned by or licensed to the
Company or, if instituted, that such challenges will not be successful. The
Company only conducts complete searches to determine whether its products
infringe upon any existing patents as it deems appropriate. The cost of
litigation to uphold the validity and prevent infringement of patents can be
substantial and require a significant commitment of management time.
Furthermore, there can be no assurance that others will not independently
develop similar technologies or duplicate the technology owned by or licensed to
the Company or design around the patented aspects of such technology. There can
be no assurance that the products and technologies the Company currently
markets, or may seek to market in the future, will not infringe patents or other
rights owned by others. In the event of an adverse outcome of any dispute with
respect to patents or other rights, the Company may be required to license 
such disputed rights to or cease using such disputed rights. There can be no 
assurance that a license would be on terms acceptable to the Company, or at all.

         The Company believes that obtaining foreign patents may be more
difficult than obtaining domestic patents because of differences in patent laws,
and recognizes that its patent position therefore may be stronger in the United
States than in Europe. In addition, the protection provided by foreign patents
once they are obtained may be weaker than that provided by domestic patents.

                                               
                                        8
<PAGE>   9
         The Company relies and expects to continue to rely upon unpatented
proprietary know-how and continuing technological innovation in the development
and manufacture of many of its principal products. The Company's policy is to
require all its employees, consultants and advisors to enter into
confidentiality agreements with the Company. There can be no assurance, however,
that these agreements will provide meaningful protection for the Company's trade
secrets or proprietary know-how in the event of any unauthorized use or
disclosure of such know-how. In addition, there can be no assurance that others
will not obtain access to or independently develop these trade secrets or
know-how.

COMPETITION

         Competition is intense among manufacturers of prescription
pharmaceuticals for the treatment of dermatological diseases, such as the
DYNACIN, TRIAZ, THERAMYCIN Z, and BENZASHAVE products, and in the OTC market for
dermatological products such as the ESOTERICA and THERAPLEX product lines, as
well as other products which the Company may develop and market in the future.
Most of the Company's competitors are large, well-established pharmaceutical,
chemical, cosmetic or health care companies with considerably greater financial,
marketing, sales and technical resources than available to the Company.
Additionally, many of the Company's present and potential competitors have
research and development capabilities that may allow such competitors to develop
new or improved products that may compete with the Company's product lines. The
pharmaceutical industry is characterized by intense competition and rapid
product development and technological change. The Company's pharmaceuticals
could be rendered obsolete or made uneconomical by the development of new
pharmaceuticals to treat the conditions addressed by the Company's products,
technological advances affecting the cost of production, or marketing or pricing
actions by one or more of the Company's competitors. The Company's business,
financial condition or results of operations could be materially adversely
affected by any one or more of such developments. Each of the Company's products
is in competition for a share of the existing market with numerous products
which have become standard treatments recommended or prescribed by
dermatologists. There can be no assurance that the Company will be able to
compete successfully against current or future competitors or that competition
will not have a material adverse effect on the Company's business, financial
condition and results of operations.

         DYNACIN competes with Minocin, a branded minocycline product marketed
by American Home Products Corporation ("AHP"), and generic minocycline products
marketed by Schein, BioCraft Laboratories, Inc. ("BioCraft"), and
Warner-Chilcott Laboratories, Inc. ("Warner-Chilcott"). Other oral antibiotics
utilized for the treatment of acne include erythromycin, doxycycline and
tetracycline marketed in branded and generic form by a variety of companies. The
Company believes that TRIAZ competes with Cleocin-T and a generic topical
clindamycin, manufactured by Pharmacia & Upjohn; Benzac, manufactured by
Galderma, Inc.; and Benzamycin, manufactured by Rhone-Poulenc Rorer. ESOTERICA
primarily competes with Porcelana, marketed by Dep Corp. and AMBI, marketed by
Kiwi Brands, a division of Sara Lee Corporation ("Kiwi").

         Several of the Company's products compete with generic (non-branded)
pharmaceuticals which claim to offer equivalent therapeutic benefits at a lower
cost. In some cases, insurers and other third-party payors seek to encourage the
use of generic products by paying or reimbursing a user or supplier of a branded
prescription product a lower portion of the purchase price then would be paid or
reimbursed for a generic product, making branded products less attractive, from
a cost perspective, to buyers. The aggressive pricing activities of the
Company's generic competitors and the payment and reimbursement policies of
third-party payors could have a material adverse impact on the Company's
business, financial condition or results of operations.

GOVERNMENT REGULATION

     Drug and Cosmetic Regulation

         The manufacture and sale of cosmetics and drugs are subject to
regulation principally by the FDA and state and local authorities in the United
States, and by comparable agencies in certain foreign countries. The Federal
Trade Commission 

                                               
                                        9
<PAGE>   10
("FTC") and state and local authorities regulate the advertising of OTC drugs
and cosmetics. The Federal Food, Drug and Cosmetic Act, the regulations
promulgated thereunder, and other federal and state statutes and regulations,
govern, among other things, the testing, manufacture, safety, effectiveness,
labeling, storage, record keeping, approval, advertising and promotion of the
Company's products. In general, products falling within the FDA's definition of
"new drugs" require premarketing clearance by the FDA. Products falling within
the FDA's definition of "cosmetics" or of "drugs" that are not "new drugs" and
that are generally recognized as "safe and effective" do not require
premarketing clearance.

         The steps required before a pharmaceutical compound may be marketed in
the United States include (i) preclinical laboratory and animal testing, (ii)
submission to the FDA of an Investigatory New Drug ("IND") application, which
must become effective before clinical trials may commence, (iii) adequate and
well-controlled clinical trials to establish the safety and efficacy of the
drug, (iv) submission to the FDA of an NDA and (v) FDA approval of the NDA prior
to any commercial sale or shipment of the drug. In addition to obtaining FDA
approval for each product, each domestic drug manufacturing establishment must
be registered with, and approved by, the FDA. Drug product manufacturing
establishments located in California also must be licensed by the State of
California in compliance with separate regulatory requirements.

         Preclinical testing is generally conducted in laboratory animals to
evaluate the potential safety and the efficacy of a drug. The results of these
studies are submitted to the FDA as a part of an IND, which must be approved
before clinical trials in humans can begin. Typically, clinical evaluation
involves a time consuming and costly three-phase process. In Phase I, clinical
trials are conducted with a small number of subjects to determine the early
safety profile, the pattern of drug distribution and metabolism. In Phase II,
clinical trials are conducted with groups of patients afflicted with a specific
disease in order to determine preliminary efficacy, optimal dosages and expanded
evidence of safety. In Phase III, large-scale, multi- center, comparative trials
are conducted with patients afflicted with a target disease in order to provide
enough data to demonstrate the efficacy and safety required by the FDA. The FDA
closely monitors the progress of each of the three phases of clinical trials and
may, at its discretion, re-evaluate, alter, suspend or terminate the testing
based upon the data which have been accumulated to that point and its assessment
of the risk/benefit ratio to the patient.

         In general, FDA approval is required before a new drug product may be
marketed in the United States. However, most OTC drugs are exempt from the FDA's
premarketing approval requirements. In 1972, the FDA instituted the ongoing OTC
Drug Review to evaluate the safety and effectiveness of OTC drugs then in the
market. Through this process, the FDA issues monographs that set forth the
specific active ingredients, dosages, indications and labeling statements for
OTC drugs that the FDA will consider generally recognized as safe and effective
and therefore not subject to premarket approval. OTC drug products are
classified by the FDA in one or more categories: Category I products, which are
deemed "safe and effective for OTC use," Category II products, which are deemed
"not generally recognized as safe and effective for OTC use," and Category III
products, which are deemed "possibly safe and effective with studies ongoing."
For certain categories of OTC drugs not yet subject to a final monograph, the
FDA usually will not take regulatory action against such a product unless
failure to do so will pose a potential health hazard to customers. Drugs subject
to final monographs, however, are subject to various FDA regulations concerning
for example, cGMP, general and specific OTC labeling requirements (including
warning statements), prohibitions against promotion for conditions other than
those stated in the labeling, and requirement that OTC drugs contain only
suitable inactive ingredients. OTC drug manufacturing facilities are subject to
FDA inspection, and failure to comply with applicable regulatory requirements
may lead to administrative or judicially imposed penalties.

         The active ingredient in DYNACIN products, minocycline, has been
approved by the FDA. The active ingredient in TRIAZ and BENZASHAVE products has
been classified as a Category III product under a tentative final FDA monograph
for over-the-counter distribution for use in treatment of labeled conditions.
The FDA has requested, and a task force of the Non-Prescription Drug
Manufacturers Association has undertaken, further studies to confirm that
benzoyl peroxide, an active ingredient in TRIAZ and BENZASHAVE products, is not
a tumor promoter when tested in conjunction with UV light exposure. TRIAZ and
BENZASHAVE products, which the Company also sells on a prescription basis, have
the same ingredients at the same dosage levels as the over-the-counter products.
In the Company's opinion, TRIAZ and BENZASHAVE products would also be considered
to be generally recognized as safe and effective for their intended uses under
the Food and Drug Act. There can be no assurance these tests will confirm the
status of benzoyl peroxide as generally recognized as safe and effective or that
adverse test results would not result 

                                               
                                       10
<PAGE>   11
in withdrawal of TRIAZ and BENZASHAVE from marketing. An adverse decision by the
FDA with respect to the safety of benzoyl peroxide could result in the
assertion of product liability claims against the Company and could otherwise
have a material adverse effect on the Company's business, financial condition
or results of operation.

         Certain ESOTERICA products contain the active ingredient hydroquinone,
currently a Category I product. Independent expert dermatologists have formally
expressed the view that hydroquinone at a 2% concentration is generally
recognized as safe and effective for its intended use. However, in 1992, with
the concurrence of the FDA, the industry initiated dermatological metabolism and
toxicity studies to fully support hydroquinone's continued Category I status.
Notwithstanding the pendency or results of these tests, which may take up to
three years to complete, the FDA may elect to classify hydroquinone as a
Category III OTC drug. The Company, in conjunction with the Non-Prescription
Drug Manufacturers Association and other manufacturers, is responsible for 50%
of the costs associated with these studies. An adverse decision by the FDA on
the safety of hydroquinone could result in the assertions of product liability
claims against the Company. Moreover, if hydroquinone is not maintained as a
Category I or Category III drug, the Company would be required to cease
marketing ESOTERICA products containing hydroquinone, which would have a
material adverse effect on the Company's business, financial condition and
results of operations.

         The ESOTERICA, TRIAZ and BENZASHAVE products must meet the composition
and labeling requirements established by the FDA for products containing their
respective basic ingredients. The Company believes that compliance with those
established standards avoids the requirement for premarketing clearance of these
products. There can be no assurance that the FDA will not take a contrary
position.

         The Company believes its three THERAPLEX moisturizers, as they are
promoted and intended by the Company for use, fall within the FDA's definition
of "cosmetics" and therefore do not require premarketing clearance. There can be
no assurance that the FDA will not take a contrary position in the future or
that an adverse determination by the FDA would not result in withdrawal of the
THERAPLEX moisturizers from marketing. The Company believes that such products
are subject to regulations governing product safety, use of ingredients,
labeling and promotion and methods of manufacture.

     Certain Factors Affecting the Company's Products

         The Company believes that certain of its products as they are promoted
and intended by the Company for use, are exempt from registration based on the
date of introduction of their active ingredients and therefore do not require
premarketing clearance. There can be no assurance that the FDA will not take a
contrary position. The Company believes that such products are subject to
regulations governing product safety, use of ingredients, advertising, labeling
and promotion and methods of manufacture.

         Clinical trials and the marketing and manufacturing of pharmaceutical
products are subject to the rigorous testing and approval processes of the FDA
and foreign regulatory authorities. The process of obtaining FDA and other
required regulatory approvals is lengthy and expensive. There can be no
assurance that the Company will be able to obtain the necessary approvals to
conduct clinical trials or for the manufacturing and marketing of products, that
all necessary clearances will be granted to the Company or its licensors for
future products on a timely basis or at all or that FDA review or other actions
will not involve delays adversely affecting the marketing and sale of the
Company's products. In addition, the testing and approval process with respect
to certain new products which the Company may develop or seek to introduce is
likely to take a substantial number of years and involve the expenditure of
substantial resources. There can be no assurance that pharmaceutical products
currently in development, or those products acquired or licensed by the Company,
will be cleared for marketing by the FDA. Failure to obtain any necessary
approvals or failure to comply with applicable regulatory requirements could
have a material adverse effect on the Company's business, financial condition or
results of operations. Further, future government regulation could prevent or
delay regulatory approval of the Company's products.

         There can be no assurance that any approval will be granted on a timely
basis, or at all, that the FDA will not require post-marketing testing and
surveillance to monitor the record of the product and continued compliance with
regulatory requirements; that the FDA will not require the submission of any lot
of any product for inspection and will not restrict the release of any lot that
does not comply with FDA standards; that the FDA will not otherwise order the
suspension of manufacturing, recall or seizure of products; or that the FDA will
not withdraw its marketing clearance of any product 

                                               
                                       11
<PAGE>   12
if compliance with regulatory standards is not maintained or if problems
concerning safety or efficacy of the product are discovered following approval.

         From time to time, the FDA has issued correspondence to pharmaceutical
companies, including the Company, alleging that their advertising or promotional
practices are false, misleading or deceptive. The Company has resolved all such
complaints without any adverse findings by the FDA and without incurring
substantial expense. However, there can be no assurance that the Company will
not receive such correspondence from the FDA in the future, or that, if such
notices are received, they will not result in substantial cost, disruption or
expense (including fines and penalties), in material changes to the manner in
which the Company promotes its products, or in loss of sales of the Company's
products or other material adverse effects on the Company's business, financial
condition or results of operations.

         For both currently marketed and future products, failure to comply with
the applicable regulatory requirements could, among other things, result in
fines, suspensions of regulatory approvals, product recalls, operating
restrictions, criminal prosecution, relabeling costs, delays in product
distribution, marketing and sales or seizure or cessation of manufacture of the
products and the imposition of civil or criminal sanctions. There can be no
assurance that the FDA will not change its position with regard to the safety or
effectiveness of the Company's current or future products or that the FDA will
agree with the Company's position regarding the regulatory status of its
products. In the event that the FDA takes a contrary position regarding any of
the Company's current or future products, the Company may be required to change
its labeling or formulation or possibly cease manufacture and marketing of such
products. In addition, even prior to any formal regulatory action, the Company
could decide voluntarily to cease distribution and sale, or to recall, any of
its products if concern about the safety or efficacy of any of its products were
to develop. Any such action could have a material adverse effect on the
Company's business, financial condition or results of operations.

         The Company also will be subject to foreign regulatory authorities
governing clinical trials and pharmaceutical sales if it seeks to market its
products outside the United States. Whether or not FDA approval has been
obtained, approval of a product by the comparable regulatory authorities of
foreign countries must be obtained prior to the commencement of marketing of the
product in those countries. The approval process varies from country to country
and the time required may be longer or shorter than that required for FDA
approval. There can be no assurance that any foreign regulatory agency will
approve any product submitted for review by the Company.

THIRD-PARTY REIMBURSEMENT

         The operating results of the Company will depend in part on the
availability of adequate reimbursement for the Company's products from
third-party payors, such as government entities, private health insurers and
managed care organizations. Third-party payors are increasingly seeking to
negotiate the pricing of medical services and products and to promote the use of
non-branded (generic) pharmaceuticals through payor-based reimbursement policies
designed to encourage their use. In some cases, third-party payors will pay or
reimburse a user or supplier of a prescription drug product only a portion of
the purchase price of the product. In the case of the Company's prescription
products, payment or reimbursement by third-party payors of only a portion of
the cost of such products could make such products less attractive, from a cost
perspective, to users, suppliers and prescribing physicians. There can be no
assurance that reimbursement, if available, will be adequate. Moreover, certain
of the Company's products are not of a type generally eligible for third-party
reimbursement. If adequate reimbursement levels are not provided by government
entities or other third-party payors for the Company's products, or if those
reimbursement policies increasingly favor the use of generic products, the
Company's business, financial condition and results of operations would be
materially adversely affected. In addition, managed care initiatives to control
costs have influenced primary care physicians to refer fewer patients to
dermatologists, resulting in a declining target market for the Company. Further
reductions in referrals to dermatologists could have a material adverse impact
upon the Company's business, financial condition or results of operations.

         In addition, a number of legislative and regulatory proposals aimed at
changing the nation's health care system have been proposed in recent years.
While the Company cannot predict whether any such proposals will be adopted, or
the effect that any such proposal may have on its business, such proposals, if
enacted, could have a material adverse effect on the Company's business,
financial condition or results of operations.

PRODUCT LIABILITY INSURANCE

                                               
                                       12
<PAGE>   13
         The Company faces an inherent risk of exposure to product liability
claims in the event that the use of its products is alleged to have resulted in
adverse effects. Such risk exists even with respect to those products that are
manufactured in licensed and regulated facilities or that otherwise possess
regulatory approval for commercial sale. There can be no assurance that the
Company will avoid significant product liability exposure. The Company currently
has product liability insurance in the amount of $5.0 million per claim and $5.0
million in the aggregate on a claims-made basis. Many of the Company's customers
require the Company to maintain product liability insurance coverage as a
condition to their conducting business with the Company. As the loss of such
insurance coverage could result in a loss of such customers, the Company intends
to take all reasonable steps necessary to maintain such insurance coverage,
although there can be no assurance that adequate insurance coverage will be
available in the future on commercially reasonable terms, or at all, or that
such insurance will be adequate to cover potential product liability claims, or
that the loss of insurance coverage or the assertion of a product liability
claim or claims would not materially adversely affect the Company's business,
financial condition and results of operations.

EMPLOYEES

         As of August 3, 1996, the Company had 58 full-time employees. The
Company believes its relationship with its employees is good. The Company
intends to hire personnel as needed during the next 12 months.
                                               
                                       13
<PAGE>   14
ITEM 2:           PROPERTIES

         The Company presently leases approximately 12,000 square feet of office
space for its headquarters in Phoenix, Arizona, under a Lease Agreement which
expires in May 2005. The Company believes that these facilities will be adequate
to meet its needs for the foreseeable future.

ITEM 3:           LEGAL PROCEEDINGS

         The Company and certain of its subsidiaries are parties to certain
actions and proceedings incident to their business. Liability in the event of
final adverse determinations in any of these matters is either covered by
insurance and/or established reserves, or, the Company believes, will not, in
the aggregate, have a material adverse effect on the business, financial
position or results of operations of the Company.

ITEM 4:           SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

         No matters were submitted to a vote of the security holders of the
Company during the fourth quarter of fiscal 1995.

                                               
                                       14
<PAGE>   15
                                     PART II

ITEM 5:           MARKET FOR REGISTRANT'S COMMON EQUITY AND RELATED STOCKHOLDER
                  MATTERS

DIVIDEND POLICY

         The Company declared a 3-for-2 stock split in the form of a 50% stock
dividend paid on August 2, 1996 to holders of record on July 22, 1996. The
Company has never declared a cash dividend. The Company intends to retain any
earnings to fund future growth and the operation of its business and, therefore,
does not anticipate paying any cash dividends in the foreseeable future.

PRICE RANGE OF COMMON STOCK

         The Company's Common Stock is traded on the Nasdaq National Market
under the symbol "MDRX." The following table sets forth for the fiscal periods
indicated, the range of high and low sales prices for the Common Stock of the
Company on the Nasdaq National Market, as adjusted to reflect the 1-for-14
reverse stock split of the Company's Common Stock effected on October 23, 1995,
and as adjusted to the nearest 1/16 to reflect the 3-for-2 stock split in the
form of a 50% stock dividend paid on August 2, 1996 to holders of record as of
July 22, 1996.

<TABLE>
<CAPTION>

                                            HIGH            LOW
                                          --------        --------
<S>                                       <C>             <C> 
FISCAL YEAR ENDED JUNE 30, 1994
        First Quarter.................    $ 8-3/16        $4-11/16
        Second Quarter................      8-3/16           3-1/2
        Third Quarter.................       7-1/2           3-1/2
        Fourth Quarter................       4-3/8          2-1/16

FISCAL YEAR ENDED JUNE 30, 1995
        First Quarter.................    4-15/16           2-1/16
        Second Quarter................      5-1/4          2-15/16
        Third Quarter.................    3-13/16           2-1/16
        Fourth Quarter................    3-13/16            1-3/4

FISCAL YEAR ENDED JUNE 30, 1996
        First Quarter.................      5-1/4           2-5/16
        Second Quarter................    10-9/16            4-1/2
        Third Quarter.................    21-1/16           9-1/16
        Fourth Quarter................     31-1/2           15-1/2
</TABLE>

         On August 14, 1996, the last reported sale price on the Nasdaq National
Market for the Company's Common Stock was $42.75 per share. As of such date,
there were approximately 750 holders of record of Common Stock.


ITEM 6:           SELECTED FINANCIAL DATA

         The following selected financial data have been derived from the 
consolidated financial statements of Medicis Pharmaceutical Corporation for the
fiscal years 1996, 1995, 1994, 1993 and 1992
                        
                                      15
<PAGE>   16
<TABLE>
<CAPTION>
                                                                             YEAR ENDED JUNE 30,
                                                          ------------------------------------------------------     
                                                            1992       1993(1)     1994(1)    1995(2)     1996
                                                          --------    --------    --------   --------   --------     
                                                                   (in thousands, except per share data)
<S>                                                       <C>         <C>         <C>        <C>        <C>  
STATEMENT OF OPERATIONS DATA:
Net sales                                                 $  7,687    $ 11,088    $ 17,059   $ 19,132   $ 25,310
Gross profit                                                 5,450       7,215      11,239     13,282     18,354
Operating expenses:
     Selling, general and administrative                     9,033      14,237(3)    8,786     10,330     10,868
     Research and development expenses                         823       3,841(4)    1,572        770        952
     Depreciation and amortization                           1,231(5)      616         653        522        559
                                                          --------    --------    --------   --------   --------     
Total operating expenses                                    11,087      18,694      11,011     11,622     12,379
                                                          --------    --------    --------   --------   --------     
Operating income (loss)                                     (5,637)    (11,479)        228      1,660      5,975
Other:
     Minority share of losses of Dyad                         --          --           677       --         --
     Gains on disposition of Dyad                             --          --          --          107       --
     Net interest income (expense)                          (2,330)       (175)       (249)       (94)        79
     Extraordinary loss on extinguishment of debt           (3,824)       --          --         --         --
     Income tax benefit (expense)                             --          --          --          (60)     1,826
Net income (loss)                                         $(11,791)   $(11,654)   $    656   $  1,613   $  7,880
Net income (loss) per share before extraordinary item     $  (2.17)   $  (2.12)   $   0.10   $   0.24   $   1.09
Extraordinary loss per share                                 (1.04)       --          --         --         --
Net income (loss) per share                               $  (3.21)   $  (2.12)   $   0.10   $   0.24   $   1.09
                                                          ========    ========    ========   ========   ========
Shares used in computing per share amount                    3,668       5,507       6,303      6,593      7,242
</TABLE>

<TABLE>
<CAPTION>
BALANCE SHEET DATA:                                                              JUNE 30,
                                                          1992       1993(1)        1994(1)     1995       1996
                                                       --------      --------      --------   --------   --------     
                                                                             (in thousands)
<S>                                                    <C>           <C>           <C>        <C>        <C>     
Cash and cash equivalents                               $ 6,136       $   233       $   775    $   953    $ 7,956
Working capital (deficiency)                             (3,528)       (4,541)       (1,978)       619     12,401
Total assets                                             17,709        11,993        12,726     13,850     26,313
Long-term debt                                            2,320         1,264           899        694        117
Stockholders' equity                                     10,325         2,937         5,263      7,387     19,460
</TABLE>

- -----------


(1)      Fiscal 1994 and fiscal 1993 include the operations of Dyad
         Pharmaceutical Corporation ("Dyad") which were divested in fiscal 1995.

(2)      Fiscal 1995 includes approximately $610,000 of charges associated with
         headquarters relocation; the Company had operating income of $2,270,000
         before relocation charges in fiscal 1995.

(3)      The increase in selling, general and administrative, was primarily
         attributable to advertising costs, most of which were due to the launch
         of DYNACIN products in November 1992.

      
                                       16
                                        
<PAGE>   17
(4)      The increase in research and development costs is primarily
         attributable to the inclusion of the allocation of the purchase price
         of Dyad to research and development and the addition of Dyad's research
         and development expenses in fiscal 1993.

(5)      Fiscal 1992 depreciation and amortization included the write-off of the
         remaining value of a license agreement previously capitalized.



ITEM 7:           MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
                  AND RESULTS OF OPERATION

         The following Management's Discussion and Analysis of Financial
Condition and Results of Operation contains forward-looking statements which
involve risk and uncertainties. The Company's actual results could differ
materially from those anticipated in these forward-looking statements as a
result of certain factors, including those set forth under "Risk Factors" and
elsewhere in this Prospectus.

OVERVIEW

         Medicis was founded in 1987 to develop and market prescription and
over-the-counter products to treat dermatological conditions. Innovative
Therapeutics, Inc. (the predecessor in interest of the Company) was incorporated
under the laws of the District of Columbia on July 1, 1987, subsequently changed
its name to Medicis Corporation and was merged with and into Medicis Corporation
(a corporation incorporated on July 29, 1988 under the laws of Delaware),
pursuant to an Agreement of Merger dated July 29, 1988. Medicis Corporation
subsequently changed its name to Medicis Pharmaceutical Corporation.

         The Company has acquired rights to manufacture and sell certain of its
dermatological products pursuant to several license and asset purchase
agreements. The Company sells these products for use in various segments of the
dermatological market, including the acne segment, the therapeutic emollient and
moisturizer segment and the fade cream segment. The Company has achieved
increases in net sales and net income both through the acquisition of products
sold by others and the launch of new products. The Company's primary
prescription products, DYNACIN products and TRIAZ products, were launched in
fiscal 1993 and fiscal 1996, respectively, and the Company's primary OTC
products, the ESOTERICA products, were acquired in fiscal 1991. Prescription
pharmaceuticals accounted for 83.2% of fiscal 1996 net sales and net sales of
70.6% and 70.7% in fiscal 1995 and fiscal 1994, respectively. DYNACIN products
accounted for a majority of the Company's total sales in fiscal 1996 and 1995.

         The Company believes that sales of DYNACIN products will continue to
constitute the majority of total net sales for the foreseeable future. 
Accordingly, any factor adversely affecting the sale of DYNACIN products would 
have a material adverse effect on the Company's business, financial condition 
and results of operations. DYNACIN products could be rendered obsolete or
uneconomical by regulatory or competitive changes. The sale of DYNACIN products
could also be affected adversely by other factors, including manufacturing or
supply interruptions, the development of new competitive pharmaceuticals to
treat the conditions addressed by DYNACIN products, technological advances,
factors affecting the cost of production, marketing or pricing actions by one or
more of the Company's competitors, changes in the prescription writing practices
of dermatologists, changes in the reimbursement policies of third-party payors,
product liability claims or other factors. See Item 1, "-- Products in
Development," "-- Manufacturing," "-- Certain License and Royalty Agreements,"
"-- Competition" and "-- Government Regulation."

         The Company's results of operation may vary from period to period due
to a variety of factors, including expenditures incurred to acquire, license and
promote pharmaceuticals, changes in prescription writing practices of
dermatologists, the Company's level of research and development, the
introduction of new products by the Company or its competitors, supply
interruptions, cost increases from third-party manufacturers, the availability
and cost of raw materials, the mix of products sold by the Company, changes in
marketing and sales expenditures, market acceptance of the Company's products,
competitive pricing pressures, seasonal fluctuations and general economic and
industry conditions that affect customer demand. In addition, the Company's
business has historically been subject to seasonal fluctuations, with lower
sales generally being experienced in the first quarter of each fiscal year. As a
result of customer buying patterns, a substantial portion of revenues has been
received in the last month of each quarter. The Company schedules its inventory
purchases to meet anticipated customer demand. As a result, relatively small
delays in the receipt of manufactured products could result in revenues being
deferred or lost. The Company's operating expenses are based on anticipated
sales levels, and a high percentage of the Company's expenses are relatively
fixed in the short-term, variations in the timing of recognition of revenue
could cause significant fluctuations from period to period and may result in
unanticipated periodic earnings shortfalls or losses. There can be no assurance
that the Company will maintain or increase revenues, maintain profitability or
avoid losses in any future period.


  
                                       17
<PAGE>   18
         The Company recognizes revenues from sales upon shipment to its
customers. At the time of sale, the Company records reserves for returns based
on estimates using historical experience. Sales are reported net of actual and
estimated product returns and net of pricing adjustments. The Company applies
royalty obligations to the cost of sales in the period the corresponding sales
are recognized.

         Medicis' customers include the nation's leading wholesale
pharmaceutical distributors, such as McKesson, Bergen Brunswig, Cardinal,
Foxmeyer, Bindley and major drug chains. During fiscal 1996, McKesson, Bergen
Brunswig and Cardinal, accounted for 15.5%, 12.2% and 11.8%, respectively, of
the Company's sales. During fiscal 1995, McKesson and Bergen Brunswig accounted
for 15.9% and 9.6%, respectively, of the Company's sales. During fiscal 1994,
McKesson and Bergen Brunswig accounted for 15.1% and 11.2%, respectively, of the
Company's sales. The loss of any of these customer accounts could have a
material adverse effect upon the Company's business, financial condition or
results of operations. See Item 1, "Business -- Customers."

         To enable Medicis to focus on its core marketing and sales activities,
the Company selectively out-sources certain non-marketing functions, such as
laboratory research, manufacturing and warehousing. As the Company expands its
activities in these areas, additional financial resources are expected to be
utilized in these areas. The Company typically does not enter into long-term
manufacturing contracts with third-party manufacturers. Whether or not such
contracts exist, there can be no assurance that the Company will be able to
obtain adequate supplies of such products in a timely fashion, or at all.

         The Company plans to spend substantial amounts of capital to continue
the research and development of its pharmaceutical products. Actual expenditures
will depend on the Company's financial position, as well as the results of
clinical testing, delays or changes in government-required testing and approval
procedures, technological and competitive developments and strategic marketing
decisions. The Company may increase total expenditures for research and
development and expects that research and development expenditures as a
percentage of net sales will fluctuate from period to period. The Company can
give no assurance that the research and development projects will provide
technologies or products that will be patentable, commercially feasible or
acceptable to government agencies whose approval may be necessary.

         The Company intends to seek additional acquisitions of product lines of
niche-market pharmaceuticals to leverage its existing distribution channels and
marketing infrastructure and to market aggressively formulations of existing
products. The success of the Company's efforts is subject to a number of risks
and uncertainties including its dependence upon key pharmaceuticals and
integration of new product acquisitions, its reliance upon third-party
manufacturers to produce certain key products, its ability to effectively manage
a changing business, uncertainties related to pharmaceutical pricing and
reimbursement and on the uncertainty of competitive forces within the
pharmaceutical industry which affect both the market for its products and the
availability of suitable product lines for acquisition which meet the Company's
acquisition criteria. The future results of operations, both annually and from
quarter to quarter, are subject to a variety of factors applicable to the
Company and to the industries and markets in which it operates. See Certain
Factors Affecting Forward Looking Statements -- Safe-Harbor Statement.

RESULTS OF OPERATIONS

     The following discussion and analysis should be read in conjunction with
the Consolidated Financial Statements and Notes to Consolidated Financial
Statements contained elsewhere herein. The following table sets forth certain
data as a percentage of net sales for the periods indicated.


                                             
                                       18
<PAGE>   19

<TABLE>
<CAPTION>
                                                                             PERCENTAGE OF SALES
                                                                              YEAR ENDED JUNE 30,
                                                          ----------------------------------------------------------
                                                            1994                      1995                    1996
                                                          --------                  --------                --------
<S>                                                         <C>                       <C>                     <C>   
Net sales.....................................              100.0%                    100.0%                  100.0%
Gross profit..................................                65.9                      69.4                    72.5
Operating expenses............................                64.6                      60.8                    48.9
Operating income..............................                 1.3                       8.6                    23.6
Net interest income (expense).................               (1.5)                     (0.5)                     0.3
Minority share of losses of Dyad..............                 4.0                        --                      --
Gains on disposition of Dyad..................                  --                       0.6                      --
Income tax benefit (expense)..................                  --                     (0.3)                     7.2
                                                          --------                  --------                --------
Net income....................................                3.8%                      8.4%                   31.1%
                                                          --------                  --------                --------
</TABLE>

<TABLE>
<CAPTION>
                                                 FISCAL 1995 AND 1996 QUARTERLY ANALYSIS
                       --------------------------------------------------------------------------------------------
                                           1995                                             1996
                                           ----                                             ----
                                                    (IN THOUSANDS, EXCEPT PER SHARE DATA)
                           SEPT.      DEC.       MAR.        JUNE            SEPT.      DEC.       MAR.     JUNE

<S>                    <C>         <C>         <C>         <C>             <C>        <C>        <C>       <C>     
Net sales              $   3,690   $  4,725    $ 5,033     $ 5,684         $  4,574   $  6,449   $ 7,016   $  7,271
Gross profit               2,519      3,024      3,659       4,080            3,257      4,667     5,040      5,390
Operating expenses         2,444      2,793      3,335       3,050            2,608      3,260     3,305      3,206
Operating income              75        231        324       1,030              649      1,407     1,735      2,184
Net income             $      26   $    308    $   312     $   967         $    646   $  1,404   $ 1,759   $  4,071
                       =========   ========    =======     =======         ========   ========   =======   ========
Net income per
share                  $      --   $   0.05    $  0.05     $  0.14         $   0.10   $   0.21   $  0.24   $   0.54
                       =========   ========    =======     =======         ========   ========   =======   ========
</TABLE>

Years Ended June 30, 1996 and 1995

     Net Sales

         Net sales for fiscal 1996 increased 32.3%, or $6.2 million, to $25.3
million from $19.1 million for fiscal 1995. The Company's net sales increased in
fiscal 1996 primarily as a result of both unit and dollar sales growth
associated with an increase in market share of the existing prescription
products and the launch of a new prescription product. The Company's
prescription products accounted for 83.2% of net sales in fiscal 1996 and 70.6%
in fiscal 1995. Net sales of the Company's prescription products grew 56.0%, or
$7.6 million, to $21.1 million in 1996 from $13.5 million in fiscal 1995,
primarily due to the Company's launch of TRIAZ products in October 1995, coupled
with an increase in market penetration of DYNACIN products. The increase in
sales of prescription products in fiscal 1996 was partially offset by a decrease
in unit sales of OTC products, primarily the ESOTERICA product line. The OTC
products accounted for 16.8% of net sales in fiscal 1996 and 28.2% in fiscal
1995. The Company continues to invest a majority of its marketing funds in the
Company's prescription products.

     Gross Profit

         Gross profit during fiscal 1996 increased 38.2%, or $5.1 million, to
$18.4 million from $13.3 million in fiscal 1995. As a percentage of net sales,
gross margin grew to 72.5% in fiscal 1996 from 69.4% in fiscal 1995 primarily as
a result of manufacturing cost reductions for DYNACIN products and a change in 
sales mix toward the Company's prescription products, which have higher gross
margins.

     Selling, General and Administrative Expenses

 
                                       19
<PAGE>   20
         Selling, general and administrative expenses in fiscal 1996 increased
5.2%, or $0.5 million, to $10.9 million from $10.3 million in fiscal 1995,
primarily due to a 22.2%, or $1.4 million, increase in selling expenses in
fiscal 1996. This increase was primarily attributable to an increase in
personnel costs commensurate with increased sales volume, yearly salary
escalations and an increase in promotional costs attributable to the launch of
TRIAZ products. Selling, general and administrative expenses in fiscal 1995
included $0.6 million in nonrecurring expenses associated with the Company's
headquarters relocation to Phoenix, Arizona in fiscal 1995.

     Research and Development Expenses

         Research and development expenses in fiscal 1996 increased 23.7%, or
$0.2 million, to $1.0 million from $0.8 million in fiscal 1995 primarily due to
development efforts relating to the introduction in October 1995 of the
Company's TRIAZ products.

     Depreciation and Amortization Expenses

         Depreciation and amortization expenses remained materially unchanged, 
at $0.6 million in fiscal 1996 and $0.5 million in fiscal 1995.

     Operating Income

         Operating income during fiscal 1996 increased 260.0%, or $4.3 million,
to $6.0 million from $1.7 million in fiscal 1995 and increased as a percentage
of net sales to 23.6% from 8.6% in fiscal 1995. This increase was primarily as a
result of higher sales volume, coupled with an increase in the Company's gross
profit margin and the absence of nonrecurring relocation expenses which were
incurred in fiscal 1995.

     Gains on Disposition and Minority Share of Losses of Dyad

         The Company had no related gains or losses in fiscal 1996. During
fiscal 1995, the Company completed the sale of all of its interest in Dyad to
Corporate Trinity. The sale of the Company's interest in Dyad resulted in a gain
of $107,000. The Company had previously consolidated Dyad's operations. As a
result of the divestiture of Dyad, the Company's and Dyad's financial statements
are no longer consolidated, subsequent to June 30, 1994. Minority share of
losses of Dyad in fiscal 1994 is based on the losses of Dyad included in
operating income.

     Net Interest Income (Expense)

         Interest income in fiscal 1996 increased 167.7%, or $96,000, to
$154,000 from $58,000 in fiscal 1995, primarily due to higher cash and cash
equivalent balances in fiscal 1996. Interest expense in fiscal 1996 decreased
49.9%, or $75,000, to $76,000, from $151,000 in fiscal 1995, primarily due to
the repayment of a substantial portion of the Company's debt.

     Income Tax Benefit (Expense)

         Income tax benefit (expense) during fiscal 1996 increased $1.9 million
to a benefit of $1.8 million from an expense of $0.1 million in fiscal 1995.
During the fourth quarter of fiscal 1996, the Company reevaluated the estimated
amount of valuation allowance required to reduce deferred tax assets in
accordance with Statement of Financial Accounting Standard No. 109, "Accounting
for Income Taxes" ("SFAS No. 109") to an amount the Company believed
appropriate. Accordingly, a credit to income tax benefit of $1.9 million was
reflected in the consolidated income statement. The amount of net deferred tax
assets estimated to be recoverable was based upon the Company's assessment of
the likelihood of near term operating income coupled with uncertainties with
respect to the impact of future competitive and market conditions. No such
income tax benefit was recorded in fiscal 1995.

     Net Income

         Net income during fiscal 1996 increased approximately 388.5%, or $6.3
million, to $7.9 million from $1.6 million in fiscal 1995. The increase was
primarily attributable to an increase in sales volume, an increase in gross
margin as a percentage of net sales and the recording of the income tax benefit
in fiscal 1996.

Years Ended June 30, 1995 and 1994

 
                                       20
<PAGE>   21
     Net Sales

         Net sales for fiscal 1995 increased 12.2%, or $2.0 million, to $19.1
million from $17.1 million for fiscal 1994. Net sales increased in fiscal 1995
primarily as a result of unit sales growth attributable to an increase in market
share of existing prescription products. The Company's prescription products
accounted for approximately 70.6% of net sales in fiscal 1995 and 70.7% in
fiscal 1994. Net sales of prescription products grew 12.0%, or $1.4 million, to
$13.5 million in fiscal 1995 from $12.1 million in fiscal 1994, primarily due to
an increase in market penetration of DYNACIN products. Net sales of OTC products
grew 12.6%, or $0.7 million, to $5.6 million in fiscal 1995 from $4.9 million in
fiscal 1994, primarily due to the Company's increased distribution in the food
and drug class of trade and an increased number of store openings by one of the
Company's major customers.

     Gross Profit

         Gross profit during fiscal 1995 increased 18.2%, or $2.1 million, to
$13.3 million from $11.2 million in fiscal 1994. As a percentage of net sales,
margins grew to 69.4% in fiscal 1995 from 65.9% in fiscal 1994, primarily as a
result of manufacturing and royalty cost reductions for DYNACIN products coupled
with a mid-year price increase.

     Selling, General and Administrative Expenses

         Selling, general and administrative expenses in fiscal 1995 increased
17.6%, or $1.5 million, to $10.3 million from $8.8 million in fiscal 1994,
primarily due to an increase in sales bonuses and other variable personnel costs
of $0.6 million and $0.6 million of nonrecurring costs associated with the
Company's relocation to Phoenix, Arizona. The Company's decision to relocate was
made in anticipation of lower operational expenses relating especially to office
lease space, personnel costs and other operating expenses. The Company also
received incentives from the State of Arizona in the form of low-interest
financing, employee training grants and travel vouchers. In addition, selling,
general and administrative expenses increased in fiscal 1995, primarily due to
the increased sampling of DYNACIN products.

     Research and Development Expenses

         Research and development expenses decreased 51.0%, or $0.8 million, to
$0.8 million in fiscal 1995 from $1.6 million in fiscal 1994, primarily due to
the exclusion of research and development expenses incurred by Dyad included in
research and development expenses in fiscal 1994. The Company divested its
entire interest in Dyad during the first quarter of fiscal 1995.

     Depreciation and Amortization Expenses

         Depreciation and amortization expenses in fiscal 1995 decreased 20.1%,
or $0.1 million, to $0.5 million from $0.6 million in fiscal 1994, primarily as
a result of the exclusion of depreciation and amortization expenses incurred by
Dyad coupled with a decrease in the weighted average balance of property and
equipment attributable to the write-off of fully-depreciated assets in fiscal
1995 as compared to fiscal 1994. Depreciation and amortization expenses incurred
by Dyad in fiscal 1995 are not included in the Company's fiscal 1995 operating
results.

     Operating Income

         Operating income during fiscal 1995 increased 627.7%, or $1.5 million,
to $1.7 million from $0.2 million in fiscal 1994, and increased as a percentage
of sales to 8.6% from 1.3% in fiscal 1994. This increase was primarily a result
of higher sales volume, an increase in the Company's gross profit margin and the
exclusion of research and development expenditures associated with Dyad in
fiscal 1995.


 
                                       21
<PAGE>   22
     Gains on Disposition and Minority Share of Losses of Dyad

         During fiscal 1995, the Company completed the sale of all of its
interest in Dyad to Corporate Trinity, resulting in a gain of approximately
$107,000. Minority share of losses of Dyad in fiscal 1994 is based on the losses
of Dyad included in operating income.

     Net Interest Income (Expense)

         Interest income in fiscal 1995 increased 96.5%, or $28,000, to $58,000
from $30,000 in fiscal 1994 primarily due to higher cash and cash equivalent
balances in 1995. Interest expense in fiscal 1995 decreased 45.8%, or $128,000,
to $151,000, from $279,000 in fiscal 1994, primarily due to the repayment of a
substantial portion of the Company's debt.

     Income Taxes

         Income taxes for fiscal 1995 were less than the federal statutory rate
due to the utilization of net operating loss carryforwards. The Company did not
incur income tax expenses for fiscal 1994.

     Net Income

         Net income during fiscal 1995 increased 146.0%, or $1.0 million, to
$1.6 million from $0.6 million in fiscal 1994, primarily due to an increase in
sales volume, coupled with an increase in the Company's gross margins.

LIQUIDITY AND CAPITAL RESOURCES

         At June 30, 1996 and June 30, 1995, the Company had cash and cash
equivalents of approximately $8.0 million and $1.0 million, respectively. The
Company's working capital was $12.4 million and $0.6 million at June 30, 1996 
and June 30, 1995, respectively.

         In fiscal 1996, the Company financed its operations through $4.9
million cash provided by operations and $3.1 million generated from the exercise
of stock options and warrants. In fiscal 1995, the Company financed operations
through cash from operations. During fiscal 1996, the Company retired two notes
with payments aggregating $750,000. During fiscal 1995, the Company made
payments aggregating $2.0 million to reduce outstanding debt and to partially
retire a note incurred in connection with a license agreement. During fiscal
1994, the Company completed a sale of shares of its Common Stock outside of the
United States, resulting in net proceeds of approximately $1.6 million.

         In May 1996, the Company obtained a $5.0 million Credit Facility from
Norwest that expires in May 1997. This Credit Facility replaced a $2.0 million
credit facility obtained from Norwest Business Credit, Inc., an affiliate of
Norwest, in August 1995. The Credit Facility is secured by substantially all of
the assets of the Company. The Company is required to comply with certain
covenants and restrictions, including covenants relating to the Company's
financial condition and results of operations. If the Company is unable or fails
to comply with the covenants and restrictions, the lender would have the right
not to make loans under the Credit Facility and to require early repayment of
any outstanding loans. The Credit Facility, as amended, is no longer subject to
a 0.5% per annum fee on the unused portion of the Credit Facility. Although the
Company has yet to draw down on the Credit Facility, the lack of availability of
loans or the requirement to make early repayment of loans or the inability of
the Company to renew the Credit Facility could have a material adverse effect on
the Company, depending on its liquidity and working capital at such time.

         At June 30, 1996 and June 30, 1995, the Company had inventories of $2.1
million and $0.8 million, respectively. The increase in inventory related to
increased sales levels and the introduction of the TRIAZ product line in October
1995. Inventories also include finished goods held at manufacturers. The
Company's inventory balances are subject to the manufacturers' scheduling of
production in order to meet future demand as conveyed to the manufacturer by the
Company. Inventories at manufacturers recorded on the consolidated balance
sheets of the Company have no effect on working capital.

         During the fourth quarter of 1996, the Company reevaluated the
estimated amount of valuation allowance required to reduce deferred tax assets
available in accordance with SFAS No. 109 to an amount the Company believed
appropriate. Accordingly, a deferred tax asset of $3.0 million was reflected in
the consolidated balance sheet with a corresponding credit to equity of $1.1
million for 1996 tax deductions related to stock option and warrant exercises
and 

    
                                       22
<PAGE>   23

a credit to deferred tax benefit of $1.9 million in the consolidated income
statement. The Company has deferred tax assets available at June 30, 1996 of
$11.6 million, which are comprised principally of the tax effect of the
Company's $26.0 million net operating loss carryforward. Deferred tax assets
available at June 30, 1996 were reduced by an $8.6 million valuation allowance.
The amount of net deferred tax assets available that are estimated to be
recoverable was based upon the Company's assessment of the likelihood of
near-term operating income coupled with the uncertainties with respect to the
impact of future competitive and market conditions. The amount of deferred tax
asset available that ultimately will be realized will depend upon future events
which are uncertain.

         In accordance with various manufacturing agreements, the Company is
required to provide manufacturers with pro forma estimated production
requirements by stock keeping units (skus) and in accordance with minimum
production runs. From time to time, the Company may not take possession of all
merchandise which has been produced by the manufacturer. The Company records its
obligation to the manufacturer at the time production is completed.

         During a portion of fiscal 1995 and prior years, the Company's cash
flow from operations was insufficient to cover its operating expenses, and
the Company relied on external financings to meet its needs for operating cash
flow. As a result of increased sales beginning in the latter half of 1995
associated with the introduction of DYNACIN, the Company experienced an increase
in accounts receivable. The Company expects that its current cash and cash
equivalents, together with additional cash from operations and cash available
from its Credit Facility and the proceeds of this offering, will be sufficient
to meet its current liquidity requirements at least through the fiscal year
ending June 30, 1998. However, depending upon the Company's acquisition and
licensing activity,  and results of operations there can be no assurance that
such resources will be sufficient. If they are not, the Company would need to
obtain additional financing. There is no assurance that such financing would be
on terms advantageous to the Company.

         Adequate additional funds, whether from the financial markets or
from other sources, may not be available on a timely basis, on terms acceptable
to the Company, or at all. Insufficient funds may cause the Company to delay,
scale back, or abandon some or all of its product acquisition, licensing,
marketing or research and development programs or opportunities.

OTHER MATTERS

         Inflation did not have a significant impact upon the results of the
Company during the fiscal 1996, 1995 or 1994.

CERTAIN FACTORS AFFECTING FORWARD LOOKING STATEMENTS - SAFE HARBOR STATEMENT

         This report contains forward-looking statements that involve risks and
uncertainties. the actual results of Medicis could differ materially from those
anticipated in these forward-looking statements as a result of certain factors
discussed elsewhere in this report, as well as the following:

DEPENDENCE ON SALES OF DYNACIN PRODUCTS

 
                                       23
<PAGE>   24
         The Company derives a majority of its revenue from sales of DYNACIN
products. The Company believes that sales of DYNACIN products will continue to
constitute the majority of net sales for the foreseeable future. Accordingly,
any factor adversely affecting the sale of DYNACIN products would have a 
material adverse effect on the Company's business, financial condition and 
results of operations. DYNACIN products could be rendered obsolete or 
uneconomical by regulatory or competitive changes. The sale of DYNACIN 
products could also be affected adversely by other factors, including 
manufacturing or supply interruptions, the development of new competitive 
pharmaceuticals to treat the conditions addressed by DYNACIN products, 
technological advances, factors affecting the cost of production, marketing or
pricing actions by one or more of the Company's competitors, changes in the 
prescription writing practices of dermatologists, changes in the reimbursement
policies of third-party payors, product liability claims or other factors. See 
Item 1, "Business -- Products in Development," "-- Manufacturing," "-- Certain
License and Royalty Agreements," "-- Competition" and "-- Government 
Regulation."

UNCERTAINTY OF FUTURE FINANCIAL RESULTS; FLUCTUATIONS IN OPERATING RESULTS

         The Company's results of operations may vary from period to period due
to a variety of factors, including expenditures incurred to acquire, license and
promote pharmaceuticals, changes in prescription writing practices of
dermatologists, the level of research and development, the introduction of new 
products by the Company or its competitors, cost increases from third-party 
manufacturers, supply interruptions, the availability and cost of raw 
materials, the mix of products sold by the Company, changes in marketing and 
sales expenditures, market acceptance of the Company's products, competitive
pricing pressures, and general economic and industry conditions that affect
customer demand. In addition, the Company's business has historically been
subject to seasonal fluctuations, with lower sales generally being experienced
in the first quarter of each fiscal year. As a result of customer buying
patterns, a substantial portion of the Company's revenues have been in the 
last month of each quarter. The Company schedules its inventory purchases to 
meet anticipated customer demand. As a result, relatively small delays in the 
receipt of manufactured products could result in revenues being deferred or 
lost. The Company's operating expenses are based on anticipated sales levels, 
and a high percentage of the Company's expenses are relatively fixed in the 
short term. Consequently, variations in the timing of recognition of revenue 
could cause significant fluctuations in operating results from period to 
period and may result in unanticipated periodic earnings shortfalls or losses. 
There can be no assurance that the Company maintain or increase revenues 
profitability or avoid losses in any future period.

INTENSE COMPETITION; UNCERTAINTY OF TECHNOLOGICAL CHANGE

         The manufacture and sale of pharmaceuticals is highly competitive. Most
of the Company's competitors are large, well-established pharmaceutical,
chemical, cosmetic or health care companies with considerably greater financial,
marketing, sales and technical resources than those available to the Company.
Additionally, many of the Company's present and potential competitors have
research and development capabilities that may allow such competitors to develop
new or improved products that may compete with the Company's product lines. The
pharmaceutical industry is characterized by intense competition and rapid
product development and technological change. The Company's pharmaceuticals
could be rendered obsolete or made uneconomical by the development of new
pharmaceuticals to treat the conditions addressed by the Company's products,
technological advances affecting the cost of production, or marketing or pricing
actions by one or more of the Company's competitors. The Company's business,
financial condition or results of operations could be materially adversely
affected by any one or more of such developments.

         DYNACIN competes with Minocin, a branded minocycline product marketed
by AHP, and generic minocycline products marketed by Schein, BioCraft and
Warner-Chilcott. Other oral antibiotics utilized for the treatment of acne
include erythromycin, doxycycline and tetracycline marketed in branded and
generic form by a variety of companies. The Company believes that TRIAZ competes
with Cleocin-T and a generic topical clindamycin, manufactured by Pharmacia &
Upjohn; Benzac, manufactured by Galderma, Inc.; and Benzamycin, manufactured by
Rhone-Poulenc Rorer. ESOTERICA primarily competes with Porcelana, marketed by
Dep Corp. and AMBI, marketed by Kiwi.

         Several of the Company's products compete with generic (non-branded)
pharmaceuticals which claim to offer equivalent therapeutic benefits at a lower
cost. In some cases, insurers and other third-party payors seek to encourage the
use of generic products by paying or reimbursing a user or supplier of a branded
prescription product a lower portion of the purchase price than would be paid or
reimbursed for a generic product, making branded products less attractive, from
a cost perspective, to buyers. The aggressive pricing activities of the 
Company's generic competitors and the


                                       24
<PAGE>   25
         payment and reimbursement policies of third-party payors could have a
material adverse effect on the Company's business, financial condition or
results of operations. See Item 1, "Business -- Competition." 

DEPENDENCE ON NEW PRODUCT INTRODUCTIONS AND ACQUISITION STRATEGY

         The Company's strategy for growth is substantially dependent upon its
continued ability to acquire pharmaceuticals targeted at the dermatology market.
The Company engages in limited proprietary research and development of new
products and must rely upon the willingness of other companies to sell or
license product lines. Other companies, including those with substantially
greater financial, marketing and sales resources, compete with the Company to
acquire such products. There can be no assurance that the Company will be able
to acquire rights to additional products on acceptable terms, or at all. The
failure of the Company to acquire additional products or successful products
could have a material adverse effect on the Company's business prospects.
Further, the market conditions, distribution channels and levels and bases of
competition with respect to internally developed or acquired products may be
different than those of the Company's current products, and there can be no
assurance that the Company will be able to compete favorably and attain market
acceptance in any newly acquired product category or successfully integrate any
acquired products or business. Failure of the Company to successfully introduce
and market new products whether internally developed or acquired from third
parties, could have a material adverse effect on the Company's business
prospects.

MANAGING CHANGING BUSINESS

         The Company's business strategy includes potential acquisitions of
products and businesses and introductions of new products. The Company
anticipates that the integration of new businesses or potential products, if
any, would require significant management time and attention. The Company's
ability to manage change will require it to continue to implement and improve
its operational, financial and management information systems and to motivate
and effectively manage an increasing number of employees. Failure to manage such
change effectively would materially adversely affect the Company's business,
financial condition and results of operations. See Item 7 and Item 1, "--
Business Strategy" and "-- Products in Development."

RISK OF PRODUCT RECALL; PRODUCT RETURNS

         Product recalls may be issued at the discretion of the Company, the
FDA, or other government agencies having regulatory authority for product sales
and may occur due to disputed labeling claims, manufacturing issues, quality
defects or other reasons. No assurance can be given that product recalls will
not occur in the future. Any product recall could materially adversely affect
the Company's business, financial condition or results of operations. The
Company's policy is to accept for return only damages or out of date products.
There can be no assurance that the Company will not grant such exceptions in the
future. The Company maintains financial reserves for the anticipated amount of
product returns based upon historical experience. There can be no assurance that
future recalls or returns would not have a material adverse affect upon the
Company's business, financial condition and results of operations.

DEPENDENCE ON KEY PERSONNEL

         The Company is dependent on certain management personnel for the
operation and development of its business. The Company has entered into an
Employment Agreement providing for full-time services with Mr. Jonah Shacknai,
the founder, Chairman and Chief Executive Officer of the Company. The current
term of the agreement of which expires on June 30, 2001, subject to automatic
renewal for periods of five years unless either party gives timely notice of an
intention not to renew the agreement. Mr. Shacknai may also terminate the
agreement prior to the end of the term. Presently, the Company carries key man
insurance on Mr. Shacknai's life in the amount of $1.0 million with the Company
as named beneficiary. Subject to the control and oversight of the Company's
Board of Directors, Mr. Shacknai exercises control over substantially all policy
making functions of the Company. In addition, the Company is dependent upon its
scientific consultants, particularly with respect to the commercial development
of discoveries and technologies as to which they have special expertise. Certain
of such consultants are employed on a full-time basis by employers other than
the Company, and some have consulting 

                                       25


<PAGE>   26
or other advisory arrangements with other entities which may conflict or compete
with their obligations to the Company. The loss of any key person, or a
reduction in the amount of time Mr. Shacknai devotes to the Company, could have
an adverse effect on the Company's business, financial condition or results of
operations.

DEPENDENCE ON LICENSES FROM OTHERS

         The Company has acquired rights to manufacture, use or market certain
of its products, as well as many of its other proposed products and
technologies, pursuant to license agreements with third parties. Such agreements
contain provisions requiring the Company to use its best efforts or otherwise
exercise diligence in pursuing market development for the subject products in
order to maintain the rights granted under the agreements and may be canceled
upon the Company's failure to perform its payment obligations. There can be no
assurance that the Company will fulfill its obligations under one or more of
such agreements due to insufficient resources, lack of successful product
development, lack of product acceptance or other reasons. The failure to satisfy
the requirements of any such agreements may result in the loss of the Company's
rights under that agreement or under related agreements and have a material
adverse effect on the Company. In addition, the Company's licensing agreements
with Seuss and Euromerican for the exclusive rights to market the THERAPLEX line
of products will terminate in October 1999 with the expiration of the related
patent. See Item 1, "Business -- Manufacturing," "-- Certain License and Royalty
Agreements,""-- Trademarks" and "-- Patents and Proprietary Rights."

RISK OF DEBT COVENANT DEFAULT

         The Company has a $5.0 million Credit Facility from Norwest that
expires in May 1997. The Credit Facility is secured by substantially all of the
assets of the Company. The Company is required to comply with certain covenants
and restrictions, including covenants relating to the Company's financial
condition or results of operations. If the Company is unable or fails to comply
with the covenants and restrictions, the lender would have the right not to make
loans under the Credit Facility and to require early repayment of any
outstanding loans. The lack of availability of loans or the requirement to make
early repayment of loans or the inability of the Company to renew the Credit
Facility could have a material adverse effect on the Company's business,
financial condition or results of operations. See Item 1, "Business -- 
Liquidity and Capital Resources."

UNCERTAINTY OF ACCESS TO CAPITAL

         During a portion of fiscal 1995 and prior years, the Company's cash
flow from operations was insufficient to cover its operating expenses, and the
Company relied on external financings to meet its needs for operating cash flow.
As a result of increased sales beginning in the latter half of 1995 associated
with the introduction of DYNACIN, the Company experienced an increase in
accounts receivable. The Company expects that its current cash and cash
equivalents, together with additional cash from operations and cash available
from its Credit Facility and the proceeds of this offering, will be sufficient
to meet its current liquidity requirements at least through the fiscal year
ending June 30, 1998. However, depending upon the Company's acquisition and
licensing activity and results of operations, there can be no assurance that
such resources will be sufficient. If they are not, the Company would need to
obtain additional financing. There is no assurance that such financing would be
on terms advantageous to the Company. Adequate additional funds, whether from
the financial markets or from other sources, may not be available on a timely
basis, on terms acceptable to the Company, or at all. Insufficient funds may
cause the Company to delay, scale back, or abandon some or all of its product
acquisition, licensing, marketing or research and development programs or
opportunities.

VOLATILITY OF COMMON STOCK PRICE

         The market price for the stocks of many publicly traded pharmaceutical
companies and marketers of dermatological products, including the Company, is
highly volatile. A variety of events, both concerning and unrelated to the
Company and the markets in which it participates, may have a significant
negative impact on the market price of the Common Stock. These factors include
regulatory developments in the health care field generally, the performance of
and product announcements by other pharmaceutical companies, manufacturing or
supply disruptions, product recalls, the loss of key personnel, and other
matters affecting the Company's products, acquisitions and financial
performance. Although the Common Stock trades on the Nasdaq National Market,
trading volume, size of institutional holdings and the number of marketmakers
has fluctuated and at times has been quite low. Both the price and volume of
trading has been sensitive to the number of analysts reporting on the Company
and such analysts' comments concerning the Company and the industry in which it
participates. The realization of any of the risks described in these "Certain
Factors Affecting Forward Looking Statements" could have a material and adverse
effect on the price of the Company's Common Stock.

   
                                       26
<PAGE>   27
CONTROL BY DIRECTORS AND OFFICERS

         As of August 3, 1996, the Company's directors and officers beneficially
own 876,623 shares of Class A Common Stock, which have one vote per share, and
112,301 shares of Class B Common Stock, and 56,150 shares of Series B Preferred
Stock, each of which have 10 votes per share, representing approximately 16.9%
of the Company's outstanding capital stock and 32.5% of the total voting power.
Accordingly, such individuals, if they vote together, are able to exercise
substantial power in the election of directors and thereby influence the
policies of the Company.

    Market Risk of Shares Eligible For Future Sales

         Subject to certain specified exceptions relating to charitable gifts,
estate planning transfers and sales relating to the exercise of expiring
options, directors, executive officers and senior staff officers of the Company,
holding in the aggregate, as of August 5, 1996, 922,154 shares of Common Stock
representing 17.5% of the shares to be outstanding upon completion of the
offering, have agreed with the Underwriters not to sell or dispose of any shares
of Common Stock for a period of 90 days following commencement of this offering
without the written consent of Robertson, Stephens & Company LLC. Sales by such
officers and directors are generally subject to the provisions of Rule 144 under
the Securities Act.

         The sale of a significant number of restricted securities, the exercise
of a significant number of options, or the offer or sale of a significant number
of shares of Common Stock acquired upon exercise of options at any one time
could materially adversely affect the market price of the Company's Common
Stock.

    Anti-Takeover Effect of Charter Provisions, Rights Plan, Delaware Law

         The Company's Certificate of Incorporation and Bylaws authorized the
Board of Directors to designate and issue, without stockholder approval,
Preferred Stock with voting, conversion and other rights and preferences that
could differentially and adversely affect the voting power or other rights of
the holders of Common Stock. The issuance of Preferred Stock or of rights to
purchase Preferred Stock could be used to discourage an unsolicited acquisition
proposal. Moreover, the Company has granted a dividend of one Preference Stock
Purchase Right ("Rights") on each outstanding share of Class A Common Stock,
Class B Common Stock and Series B Preferred Stock. Under certain circumstances,
after a person has acquired beneficial ownership of a certain percentage of the
Common Stock, each Right will entitle the holder to purchase, at the Right's
then-current exercise price, stock of the Company or its successor at a
discount. In addition, certain provisions of Delaware law applicable to the
Company and certain provisions of the Company's Certificate of Incorporation and
Bylaws could also delay or make more difficult a merger, tender offer or proxy
contest involving the Company, including Section 203 of the Delaware Business
Corporation Law, which prohibits a Delaware corporation from engaging in any
business combination with any interested stockholder for a period of three years
unless certain conditions are met. All of the Company's stock option plans
provide for the acceleration of vesting in the event of a change in control in
the Company and Mr. Shacknai's Employment Agreement provides for certain
payments upon a change in control, as well as an acceleration of vesting of
options previously granted to him. The possible issuance of Preferred Stock, the
rights granted to stockholders under the Rights Plan, Delaware law, provisions
of the Certificate of Incorporation and Bylaws and the Company's stock option
plans and Mr. Shacknai's Employment Agreement could each have the effect of
delaying, deferring or preventing a change in control of the Company including,
without limitation, discouraging a proxy contest, making more difficult the
acquisition of a substantial block of the Company's Common Stock or limiting the
price that investors might in the future be willing to pay for shares of the
Common Stock. Under certain circumstances, Mr. Shacknai's Employment Agreement
requires the Company to make payments that would constitute excess parachute
payments under the Internal Revenue Code of 1986, as amended. In the event that
the Company was required to make payments constituting excess parachute
payments, payments to Mr. Shacknai would not be deductible by the Company, and
Mr. Shacknai would be required to pay an excise tax.

LACK OF CASH DIVIDENDS

         The Company has never paid any cash dividends on its capital stock and
does not anticipate that any cash dividends will be declared or paid in the
foreseeable future.


ITEM 8:           FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

  
                                       27

<PAGE>   28
         The Company's financial statements and schedule at December 31, 1996
and 1995 and for each of the three years in the period ending June 30, 1996 and
the Independent Auditors' Report thereon and contained on pages F-1 through F-16
and S-1 of this Form 10-K.


ITEM 9:         CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING AND
                FINANCING DISCLOSURE

     Not applicable.

    
                                       28
<PAGE>   29
                                    PART III

ITEM 10:          DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT



ITEM 11:          EXECUTIVE COMPENSATION



ITEM 12:          SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT



ITEM 13:          CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

         The information called for by Items 10, 11, 12 and 13 are incorporated
by reference to the Company's definitive proxy statement for the 1996 Annual
Meeting of Stockholders to be filed pursuant to Regulation 14A.


    
                                       29
<PAGE>   30
                                     PART IV

ITEM 14:        EXHIBITS, FINANCIAL STATEMENT SCHEDULES AND REPORTS ON FORM 8-K

<TABLE>
<CAPTION>
                                                                                                 Page
                                                                                                 ----
<S>                                                                                              <C> 
     (a)  Documents filed as a part of this Report.

          (1)      Financial Statements:

                   Index to Consolidated Financial Statements..............................       F-1

                   Report of Ernst & Young LLP, Independent Auditor.........................      F-2

                   Consolidated balance sheets at June 30, 1996 and 1995...................       F-3

                   Consolidated statements of income for the years ended
                   June 30, 1996, 1995 and 1994............................................       F-5

                   Consolidated statement of stockholders' equity for the years
                   ended June 30, 1996, 1995 and 1994......................................       F-6

                   Consolidated statements of cash flows for the years ended June 30, 1996,
                   1995 and 1994...........................................................       F-7

                   Notes to consolidated financial statements..............................       F-8

          (2)      Financial Statement Schedules:

                   Schedule II - Valuation and Qualifying Account..........................       S-1

                   The financial statement schedule should be read in
                   conjunction with the consolidated financial
                   statements. Financial statement schedules not
                   included in this Annual Report on Form 10-K have been
                   omitted because they are not applicable or the
                   required information is shown in the financial
                   statements or notes thereto.

          (3)      Exhibits filed as part of this Report:
</TABLE>

<TABLE>
<CAPTION>
          Exhibit No.       Description
          -----------       -----------
<S>                         <C>
              3.1       -   Certificate of Incorporation of the Company, as amended.(11)
              3.3       -   By-Laws of the Company.(1)
              4.1       -   Rights Agreement, dated as of August 17, 1995, between the Company and American
                            Stock Transfer & Trust Company, as Rights Agent.(11)
              4.3       -   Form of specimen certificate representing Class A Common Stock.(2)
             
</TABLE>

    
                                       30

<PAGE>   31
<TABLE>
<S>                          <C>

              10.1       -   License Agreement among Euromerican Trade Resources, Inc., Dr. H.R. Suess and
                             H.R. Suess A.G. dated as of September 24, 1987.(3)
              10.2       -   Modification to License Agreement among the Company, Euromerican Trade
                             Resources, Inc., Dr. H.R. Suess and H.R. Suess A.G. dated as of April 6, 1989.(3)
              10.3       -   Letter Agreement between the Company and Euromerican Trade Resources, Inc. dated
                             as of April 6, 1989, relating to Modification to License Agreement among the
                             Company, Euromerican Trade Resources, Inc., Dr. H.R. Suess and H.R. Suess A.G.
                             dated as of April 6, 1989.(3)
              10.8       -   Medicis Pharmaceutical Corporation 1995 Stock Option Plan (incorporated by
                             references to Exhibit C to the definitive Proxy Statement for the 1995 Annual Meeting
                             of Stockholders previously filed with the SEC, File No. 0-18443).
              10.9       -   Employment Agreement between the Company and Jonah Shacknai dated as of
                             July 24, 1996.(15)
             10.10       -   Medicis Pharmaceutical Corporation 1988 Stock Option Plan, as amended.(4)
             10.12       -   License Agreement between the Company and Dr. H.R. Suess dated March 1, 1990.(3)
             10.13       -   License Agreement between Syosset Laboratories, Inc. and Medicis Dermatologics,
                             Inc. dated as of July 25, 1990 and the Guaranty of the Company.(5)
             10.14       -   Non-Exclusive License Agreement between Syosset Laboratories, Inc. and Medicis
                             Dermatologics, Inc. dated as of July 25, 1990 and the Guaranty of the Company.(5)
             10.15       -   Manufacturing Agreement between Syosset Laboratories, Inc. and Medicis
                             Dermatologics, Inc. dated as of July 25, 1990 and the Guaranty of the Company.(5)
             10.16       -   Sales Agency Agreement between Syosset Laboratories, Inc. and Medicis
                             Dermatologics, Inc. dated as of July 25, 1990 and the Guaranty of the Company.(5)
             10.18       -   Medicis Pharmaceutical Corporation 1990 Stock Option Plan, as amended.(4)
</TABLE>

    
                                       31
<PAGE>   32
<TABLE>
<S>                          <C>
             10.46       -   Option to Purchase 2,678 Shares of Class A Common Stock of the Company, dated
                             December 3, 1991.(6)
             10.49       -   Option to Purchase Class A Common Stock granted to Stephen B. Booke.(4)
             10.50       -   Option to Purchase Class A Common Stock granted to Gerald Amato.(4)
             10.58       -   Medicis Pharmaceutical Corporation 1992 Stock Option Plan.(8)
             10.59       -   Supply Agreement, dated as of October 21, 1992, between Schein and the
                             Company.(7)
             10.69       -   Purchase Agreement, dated May 21, 1993, between the Company and Bindley
                             Western Drug Company.(9)
             10.70       -   Amendment to Manufacturing and Supply Agreement, dated March 2, 1993, between
                             Schein and the Company.(10)
             10.71       -   Manufacturing and Supply Agreement, dated as of March 15, 1995, between
                             SmithKline Beecham Consumer Healthcare, L.P. and the Company.(11)
             10.72(a)    -   Credit and Security Agreement, dated as of August 3, 1995, between the Company and
                             Norwest Business Credit, Inc.(12) 
             10.72(b)    -   First Amendment to Credit and Security Agreement, dated as of May 29, 1996,
                             between the Company and Norwest Bank Arizona, N.A.(15)
             10.73(a)   -    Patent Collateral Assignment and Security Agreement, dated as of August 3, 1995, by
                             the Company to Norwest Business Credit, Inc.(13)
             10.73(b)   -    First Amendment to Patent Collateral Assignment and Security Agreement, dated as
                             of May 29, 1996, by the Company to Norwest Bank Arizona, N.A.(15)
             10.74(a)   -    Trademark Collateral Assignment and Security Agreement, dated as of August 3,
                             1995, by the Company to Norwest Business Credit, Inc.(14)
             10.74(b)   -    First Amendment to Trademark Collateral Assignment and Security Agreement, dated as
                             of May 29, 1996, by the Company to Norwest Bank Arizona, N.A.(15)
             10.75      -    Assignment and Assumption of Loan Documents, dated as of May 29, 1996, from
                             Norwest Business Credit, Inc., to and by Norwest Bank Arizona, N.A.(15)
             10.76      -    Multiple Advance Note, dated May 29, 1996, from the Company to Norwest Bank
                             Arizona, N.A.(15)
             21.1       -    Subsidiaries.(15)
             23.1       -    Consent of Ernst & Young LLP(15).
             24.1       -    Power of Attorney (See page 34).
             27.1       -    Financial Data Schedule(15).
</TABLE>

- ------------

         (1)      Incorporated by reference to the exhibit with the same number
                  in the Company's Quarterly Report on Form 10-Q for the quarter
                  ended December 31, 1992, File No. 0-18443, previously filed
                  with the Securities and Exchange Commission (the "SEC").

         (2)      Incorporated by reference to the exhibit with the same number
                  in the Registration Statement on Form S-1 of the Registrant,
                  File No. 33-32918, filed with the SEC on January 16, 1990.

         (3)      Incorporated by reference to the exhibit with the same number
                  in Amendment No. 1 to the Registration Statement on Form S-1
                  of the Company, File No. 33-32918, filed with the SEC on March
                  6, 1990.

         (4)      Incorporated by reference to the exhibit with the same number
                  in the Company's Annual Report on Form 10-K for the fiscal
                  year ended June 30, 1992, as amended, File No. 0-18443
                  previously filed with the SEC.

         (5)      Incorporated by reference to the exhibit with the same number
                  in Amendment No. 2 to the Registration Statement on Form S-1
                  of the Company, File No. 33-34041, filed with the SEC on
                  August 2, 1990.

   
                                       32
<PAGE>   33
         (6)      Incorporated by reference to the exhibit with the same number
                  in Amendment No. 1 to the Registration Statement on Form S-1
                  of the Company, File No. 33-46913, filed with the SEC on April
                  29, 1992.

         (7)      Incorporated by reference to the exhibit with the same number
                  in Registration Statement on Form S-1 of the Company, File No.
                  33-54276, filed with the SEC on June 11, 1993.

         (8)      Incorporated by reference to Exhibit B to the Company's
                  definitive Proxy Statement for its 1992 Annual Meeting of
                  Stockholders, previously filed with the SEC, File No. 0-18443.

         (9)      Incorporated by reference to the exhibit with the same number
                  in Amendment No. 1 to the Registration Statement on Form S-1
                  of the Company, File No. 33-54276, filed with the SEC on May
                  25, 1993.

         (10)     Incorporated by reference to the exhibit with the same number
                  in the Company's Annual Report on Form 10-K for the fiscal
                  year ended June 30, 1993, File No. 0-18443, filed with the SEC
                  on October 13, 1993.

         (11)     Incorporated by reference to the exhibit with the same number
                  in the Company's Annual Report on Form 10-K for the fiscal
                  year ended June 30, 1995, File No. 0-18443, filed with the SEC
                  on September 27, 1995 ("1995 Form 10-K").

         (12)     Incorporated by reference to exhibit number 4.2 in the 1995
                  Form 10-K. 

         (13)     Incorporated by reference to exhibit number 4.4 in the 1995
                  Form 10-K. 

         (14)     Incorporated by reference to exhibit number 4.5 in the 1995
                  Form 10-K. 

         (15)     Filed herewith.

(b)      A Report on Form 8-K was filed with the Securities and Exchange
         Commission on August 12, 1996 relating to the 3-for-2 stock split
         in the form of a 50% stock dividend paid on August 2, 1996 to holders
         of record on July 22, 1996.

(c)      The exhibits to this Form 10-K follow the Company's Financial Statement
         Schedule included in this Form 10-K.

(d)      The Financial Statement Schedule to this Form 10-K appears on page S-1
         of this Form 10-K.

   
                                       33
<PAGE>   34
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                   INDEX TO CONSOLIDATED FINANCIAL STATEMENTS
 
<TABLE>
<CAPTION>
                                                                                        PAGE
                                                                                        -----
<S>                                                                                     <C>
Report of Ernst & Young LLP, Independent Auditors.....................................    F-2
Consolidated Balance Sheets...........................................................    F-3
Consolidated Statements of Income.....................................................    F-5
Consolidated Statement of Stockholders' Equity........................................    F-6
Consolidated Statements of Cash Flows.................................................    F-7
Notes to Consolidated Financial Statements............................................    F-8
</TABLE>
 
                                       F-1
<PAGE>   35
 
               REPORT OF ERNST & YOUNG LLP, INDEPENDENT AUDITORS
 
The Board of Directors and Stockholders
Medicis Pharmaceutical Corporation
 
     We have audited the accompanying consolidated balance sheets of Medicis
Pharmaceutical Corporation as of June 30, 1996 and 1995, and the related
consolidated statements of income, stockholders' equity, and cash flows for each
of the three years in the period ended June 30, 1996. Our audits also included
the financial statement schedule listed in the Index at Item 14(a). These
financial statements and schedule are the responsibility of the Company's
management. Our responsibility is to express an opinion on these financial
statements and schedule based on our audits.
 
     We conducted our audits in accordance with generally accepted auditing
standards. Those standards require that we plan and perform the audit to obtain
reasonable assurance about whether the financial statements are free of material
misstatement. An audit includes examining, on a test basis, evidence supporting
the amounts and disclosures in the financial statements. An audit also includes
assessing the accounting principles used and significant estimates made by
management, as well as evaluating the overall financial statement presentation.
We believe that our audits provide a reasonable basis for our opinion.
 
     In our opinion, the consolidated financial statements referred to above
present fairly, in all material respects, the consolidated financial position of
Medicis Pharmaceutical Corporation at June 30, 1996 and 1995, and the
consolidated results of its operations and its cash flows for each of the three
years in the period ended June 30, 1996, in conformity with generally accepted
accounting principles. Also, in our opinion, the related financial statement
schedule, when considered in relation to the basic financial statements taken as
a whole, presents fairly in all material respects the information set forth
therein.
 
                                          ERNST & YOUNG LLP
 
Phoenix, Arizona
August 2, 1996
 
                                       F-2
<PAGE>   36
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                          CONSOLIDATED BALANCE SHEETS
 
                                     ASSETS
 
<TABLE>
<CAPTION>
                                                                             JUNE 30,
                                                                    ---------------------------
                                                                       1996            1995
                                                                    -----------     -----------
<S>                                                                 <C>             <C>
ASSETS
  Current assets:
     Cash and cash equivalents....................................  $ 7,956,050     $   953,438
     Accounts receivable, less allowance:
       1996: $680,000; 1995: $520,000.............................    5,210,704       4,214,424
     Inventories..................................................    2,080,014         798,956
     Deferred tax assets..........................................    3,000,000              --
     Other current assets.........................................      738,911         251,086
                                                                    -----------     -----------
          Total current assets....................................   18,985,679       6,217,904
Property and equipment, at cost:
  Furniture and equipment.........................................      336,544         201,009
  Leasehold improvements..........................................      170,000         170,000
                                                                    -----------     -----------
                                                                        506,544         371,009
     Less accumulated depreciation................................      100,897          54,907
                                                                    -----------     -----------
          Net property and equipment..............................      405,647         316,102
Intangible assets, at cost:
  Patents, trademarks and licenses................................      203,326         131,554
  Intangible assets related to ESOTERICA product acquisition......    9,168,853       9,168,853
                                                                    -----------     -----------
                                                                      9,372,179       9,300,407
     Less accumulated amortization................................    2,450,705       1,984,269
                                                                    -----------     -----------
          Net intangible assets...................................    6,921,474       7,316,138
                                                                    -----------     -----------
                                                                    $26,312,800     $13,850,144
                                                                    ===========     ===========
</TABLE>
 
                            See accompanying notes.
 
                                       F-3
<PAGE>   37
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                          CONSOLIDATED BALANCE SHEETS
 
                      LIABILITIES AND STOCKHOLDERS' EQUITY
 
<TABLE>
<CAPTION>
                                                                            JUNE 30,
                                                                  -----------------------------
                                                                      1996             1995
                                                                  ------------     ------------
<S>                                                               <C>              <C>
LIABILITIES
  Current liabilities:
     Accounts payable...........................................  $  3,371,184     $  3,227,173
     Accrued officer's salaries.................................       204,750          204,750
     Accrued royalties..........................................       552,952          468,182
     Notes payable..............................................        10,000          140,000
     Accrued incentives.........................................     1,184,111          631,231
     Other accrued liabilities..................................     1,262,134          927,243
                                                                      --------         --------
          Total current liabilities.............................     6,585,131        5,598,579
ESOTERICA products acquisition payables, net of discount of:
  1995: $13,100.................................................            --          586,900
Note payable....................................................       116,580          107,437
Other non-current liabilities...................................       151,437          170,234
COMMITMENTS AND CONTINGENCIES
STOCKHOLDERS' EQUITY
Preferred Stock, $0.01 par value, 4,937,340 shares authorized;
  no shares issued..............................................            --               --
Series B Automatically Convertible Preferred Stock, $0.01 par
  value, shares authorized, issued and outstanding: 62,660 at
  June 30, 1996 and 1995........................................           627              627
Class A Common Stock, $0.014 par value, shares authorized:
  10,000,000; issued and outstanding: 1996: 6,816,318 1995:
  6,498,843.....................................................        95,429           90,984
Class B Common Stock, $0.014 par value, shares authorized,
  issued and outstanding: 1996 and 1995: 125,322................         1,754            1,754
Additional paid-in capital......................................    44,251,722       40,063,251
Accumulated deficit.............................................   (24,889,880)     (32,769,622)
                                                                      --------         --------
          Total stockholders' equity............................    19,459,652        7,386,994
                                                                      --------         --------
                                                                  $ 26,312,800     $ 13,850,144
                                                                      ========         ========
</TABLE>
 
                            See accompanying notes.
 
                                       F-4
<PAGE>   38
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                       CONSOLIDATED STATEMENTS OF INCOME
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED JUNE 30,
                                                      -------------------------------------------
                                                         1996            1995            1994
                                                      -----------     -----------     -----------
<S>                                                   <C>             <C>             <C>
Net sales...........................................  $25,309,743     $19,131,665     $17,058,504
Operating costs and expenses:
  Cost of sales.....................................    6,955,685       5,849,886       5,819,275
  Selling, general and administrative (includes
     relocation charges of $609,762 for the year
     ended June 30, 1995)...........................   10,867,979      10,330,162       8,786,192
  Research and development..........................      951,888         769,577       1,571,769
  Depreciation and amortization.....................      558,802         522,221         653,192
                                                      -----------     -----------     -----------
     Operating costs and expenses...................   19,334,354      17,471,846      16,830,428
                                                      -----------     -----------     -----------
Operating income....................................    5,975,389       1,659,819         228,076
Minority share of losses of Dyad....................           --              --         677,000
Gain on disposition of Dyad.........................           --         106,640              --
Interest income.....................................      154,023          57,543          29,287
Interest expense....................................      (75,670)       (150,895)       (278,652)
                                                      -----------     -----------     -----------
Income before taxes.................................    6,053,742       1,673,107         655,711
Income tax benefit (expense)........................    1,826,000         (60,000)             --
                                                      -----------     -----------     -----------
Net income..........................................  $ 7,879,742     $ 1,613,107     $   655,711
                                                      ===========     ===========     ===========
Net income per common and common equivalent share...  $      1.09     $      0.24     $      0.10
                                                      ===========     ===========     ===========
Shares used in computing net income per common and
  common equivalent share...........................    7,242,162       6,593,164       6,303,453
                                                      ===========     ===========     ===========
</TABLE>
 
                            See accompanying notes.
 
                                       F-5
<PAGE>   39
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY
 
<TABLE>
<CAPTION>
                                 SERIES B
                               AUTOMATICALLY
                                CONVERTIBLE           CLASS A             CLASS B
                              PREFERRED STOCK      COMMON STOCK         COMMON STOCK     ADDITIONAL
                              ---------------   -------------------   ----------------     PAID-IN     ACCUMULATED
                              SHARES   AMOUNT    SHARES     AMOUNT    SHARES    AMOUNT     CAPITAL       DEFICIT         TOTAL
                              ------   ------   ---------   -------   -------   ------   -----------   ------------   -----------
<S>                           <C>      <C>      <C>         <C>       <C>       <C>      <C>           <C>            <C>
Balance at June 30, 1993....  62,660    $627    5,591,227   $78,277   125,322   $1,754   $37,894,565   $(35,038,440)  $ 2,936,783
  Shares issued in
    connection with
    Regulation S offering...                      671,902    9,407                         1,637,542                    1,646,949
  Options issued in lieu of
    payment for services
    rendered................                                                                  24,000                       24,000
  Net income................                                                                               655,711        655,711
                              ------    ----    ---------   -------   -------   ------   -----------   ------------   -----------
Balance at June 30, 1994....  62,660     627    6,263,129   87,684    125,322   1,754     39,556,107   (34,382,729 )    5,263,443
  Shares issued in
    connection with private
    offering................                      235,714    3,300                           507,144                      510,444
  Net income................                                                                             1,613,107      1,613,107
                              ------    ----    ---------   -------   -------   ------   -----------   ------------   -----------
Balance at June 30, 1995....  62,660     627    6,498,843   90,984    125,322   1,754     40,063,251   (32,769,622 )    7,386,994
  Exercise of stock options
    and warrants, net.......                      317,475    4,445                         3,101,471                    3,105,916
  Tax effect of stock
    options exercised.......                                                               1,067,000                    1,067,000
  Options issued in lieu of
    payment for services
    rendered................                                                                  20,000                       20,000
  Net income................                                                                             7,879,742      7,879,742
                              ------    ----    ---------   -------   -------   ------   -----------   ------------   -----------
Balance at June 30, 1996....  62,660    $627    6,816,318   $95,429   125,322   $1,754   $44,251,722   $(24,889,880)  $19,459,652
                              ======    ====    =========   =======   =======   ======   ===========   ============   ===========
</TABLE>
 
                            See accompanying notes.
 
                                       F-6
<PAGE>   40
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                     CONSOLIDATED STATEMENTS OF CASH FLOWS
 
<TABLE>
<CAPTION>
                                                                  YEAR ENDED JUNE 30,
                                                      -------------------------------------------
                                                         1996            1995            1994
                                                      -----------     -----------     -----------
<S>                                                   <C>             <C>             <C>
OPERATING ACTIVITIES:
  Net income........................................  $ 7,879,742     $ 1,613,107     $   655,711
  Adjustments to reconcile net income to net cash
     provided by (used in) operating activities:
     Depreciation and amortization..................      558,802         522,221         653,192
     Non-cash interest..............................       13,100          49,602          45,410
     Other non-cash expenses........................       20,000              --          24,000
     Deferred income tax benefit....................   (1,933,000)             --              --
     Allowance for doubtful accounts and returns....      160,000         120,000         160,000
     Minority share of losses of Dyad...............           --              --        (677,000)
     Changes in operating assets and liabilities:
       Accounts receivable..........................   (1,156,280)     (1,154,922)     (2,380,654)
       Inventories..................................   (1,281,058)       (370,929)      1,457,239
       Other current assets.........................     (487,825)        (48,013)        (29,231)
       Accounts payable.............................      144,011       1,282,949      (1,284,786)
       Accrued officer's salaries...................           --              --          (3,334)
       Accrued royalties............................       84,770          70,601         257,639
       Interest payable.............................           --        (250,016)        (60,743)
       Accrued incentives...........................      552,880         222,711        (107,774)
       Other accrued liabilities....................      334,891        (307,792)       (319,787)
                                                      -----------     -----------     -----------
          Net cash provided by (used in) operating
            activities..............................    4,890,033       1,749,519      (1,610,118)
INVESTING ACTIVITIES:
  Purchase of property and equipment................     (181,911)       (140,754)        (12,029)
  Payments of license agreement and ESOTERICA
     products acquisition...........................           --              --          (8,838)
  Other, net........................................      (71,772)         (7,885)        (31,317)
                                                      -----------     -----------     -----------
          Net cash used in investing activities.....     (253,683)       (148,639)        (52,184)
FINANCING ACTIVITIES:
  Sales of common equity securities.................           --         510,444       1,646,949
  Proceeds from issuance of note payable............        9,143         107,437              --
  Principal payments of debt........................     (748,797)     (2,040,000)       (120,000)
  Proceeds from sale of equity in Dyad..............           --              --         677,000
  Proceeds from the exercise of options/warrants....    3,105,916              --              --
                                                      -----------     -----------     -----------
          Net cash provided by (used in) financing
            activities..............................    2,366,262      (1,422,119)      2,203,949
  Net increase in cash and cash equivalents.........    7,002,612         178,761         541,647
  Cash and cash equivalents at beginning of year....      953,438         774,677         233,030
                                                      -----------     -----------     -----------
  Cash and cash equivalents at end of year..........  $ 7,956,050     $   953,438     $   774,677
                                                      ===========     ===========     ===========
  Supplemental disclosures of cash flow information:
     Cash paid during the year for:
       Interest.....................................  $   243,570     $   351,309     $   301,044
       Taxes........................................      132,233          79,631          79,237
</TABLE>
 
                            See accompanying notes.
 
                                       F-7
<PAGE>   41
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
 
                                 JUNE 30, 1996
 
NOTE 1.  FORMATION AND DEVELOPMENT OF THE COMPANY
 
     Medicis Pharmaceutical Corporation and its wholly owned subsidiaries
("Medicis" or the "Company") is an independent pharmaceutical company in the
United States offering prescription and non-prescription (over-the-counter)
products exclusively to treat dermatological conditions. The Company has
acquired rights to manufacture and sell certain of its dermatological products
pursuant to several license and asset purchase agreements. The Company sells
these products for use in various segments of the dermatological market,
including the acne segment, the therapeutic emollient and moisturizer segment
and the fade cream segment.
 
NOTE 2.  SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES
 
PRINCIPLES OF CONSOLIDATION
 
     The accompanying consolidated financial statements include the accounts of
Medicis and all wholly owned subsidiaries, and through June 30, 1994, the
accounts of Dyad Pharmaceutical Corporation ("Dyad") (see Note 4). The Company
has since sold its interest in Dyad and, accordingly, the accounts of Dyad have
not been consolidated subsequent to June 30, 1994. All significant intercompany
accounts and transactions have been eliminated in consolidation. Certain prior
period amounts have been reclassified to conform to the current period
presentation.
 
RESEARCH AND DEVELOPMENT COSTS
 
     All research and development costs, including payments related to products
under development and research consulting agreements, are expensed as incurred.
 
INTANGIBLE ASSETS
 
     Legal fees and other direct costs incurred in obtaining and protecting
patents and trademarks are capitalized as incurred. When patent applications are
approved or trademarks are registered, these costs are amortized over the
shorter of the useful life of the patent or trademark, or the related product on
the straight-line basis. The costs are expensed if and when it is concluded that
nonapproval is probable or, in the Company's opinion, the patent or trademark
should be abandoned. Intangible assets resulting from the ESOTERICA line of skin
care products (the "ESOTERICA products") acquisition principally consist of the
excess of the acquisition cost over the fair value of the net assets acquired
and are being amortized on a straight-line basis over twenty years. The Company
assesses the recoverability of intangible assets resulting from the ESOTERICA
products acquisition based on the gross profit of the related products over the
remaining amortization period.
 
CASH AND CASH EQUIVALENTS
 
     At June 30, 1996, cash equivalents include highly liquid investments of
approximately $7,500,000 invested largely in money market accounts consisting of
government securities and high-grade commercial paper. These investments are
stated at cost which approximates fair value. The Company considers all highly
liquid investments purchased with a remaining maturity of three months or less
to be cash equivalents.
 
INVENTORIES
 
     The Company utilizes third parties to manufacture and package inventories
held for sale, takes title to certain inventories once manufactured, and
warehouses such goods until packaged for final
 
                                       F-8
<PAGE>   42
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
distribution and sale. Inventories consist of salable dermatological products
held at the Company's warehouses as well as at the manufacturers' facilities and
are valued at the lower of cost or market as more determined by their net
realizable value using the first-in, first-out method.
 
     Inventories are as follows:
 
<TABLE>
<CAPTION>
                                                                          JUNE 30,
                                                                   -----------------------
                                                                      1996          1995
                                                                   ----------     --------
    <S>                                                            <C>            <C>
    Raw materials................................................  $   72,633           --
    Work in progress.............................................      23,749     $ 37,971
    Finished goods...............................................   1,983,632      760,985
                                                                   ----------     --------
      Total inventories..........................................  $2,080,014     $798,956
                                                                   ==========     ========
</TABLE>
 
DEPRECIATION AND AMORTIZATION
 
     Property and equipment are stated at cost. Depreciation is calculated on
the straight-line basis over the estimated useful lives of property and
equipment (three to five years). Leasehold improvements are amortized over the
shorter of their estimated useful lives or the remaining lease term.
 
REVENUE RECOGNITION
 
     The Company recognizes product revenue upon shipment to its customers. The
Company records reserves for returns based on estimates at the time of sale.
 
ADVERTISING
 
     The Company expenses advertising as incurred. Advertising expenses for the
fiscal years ended June 30, 1996 ("Fiscal 1996"), June 30, 1995 ("Fiscal 1995")
and June 30, 1994 ("Fiscal 1994") were approximately $1,887,000, $1,525,000 and
$1,408,000, respectively.
 
STATEMENTS OF CASH FLOWS
 
     Non-cash investing and financing activities were as follows:
 
<TABLE>
<CAPTION>
                                                                 YEAR ENDED JUNE 30,
                                                         -----------------------------------
                                                            1996          1995        1994
                                                         ----------     --------     -------
    <S>                                                  <C>            <C>          <C>
    Property and equipment acquired under capital lease
      obligations......................................          --     $170,234          --
    Options/warrants issued in lieu of payment for
      services rendered................................  $   20,000           --     $24,000
    Tax benefit of stock options exercised.............   1,067,000           --          --
</TABLE>
 
NET INCOME PER COMMON AND COMMON EQUIVALENT SHARE
 
     Net income per common and common equivalent share have been computed by
using the weighted average number of shares outstanding and common equivalent
shares. Net income per share has been adjusted to reflect the 3-for-2 stock
split described in Note 7.
 
INCOME TAXES
 
     Income taxes have been provided using the liability method in accordance
with Statement of Financial Accounting Standards No. 109, Accounting for Income
Taxes("SFAS No. 109").
 
                                       F-9
<PAGE>   43
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
USE OF ESTIMATES
 
     The preparation of the consolidated financial statements in conformity with
generally accepted accounting principles requires management to make estimates
and assumptions that affect the amounts reported in the consolidated financial
statements and accompanying notes. Actual results could differ from those
estimates based upon future events, which could include, among other risks,
changes in the regulations governing the manner in which the Company sells its
products, changes in health care environment and the reliance on contract
manufacturing services.
 
FAIR VALUE OF FINANCIAL INSTRUMENTS
 
     The carrying amount of cash and cash equivalents, accounts receivable,
accounts payable and long-term debt reported in the consolidated balance sheets
approximate their fair value.
 
IMPACT OF RECENTLY ISSUED ACCOUNTING STANDARDS
 
     In March, 1995, the Financial Accounting Standards Board ("FASB") issued
Statement No. 121, Accounting for the Impairment of Long-Lived Assets and for
Long-Lived Assets to be Disposed Of, which requires the revaluation of
long-lived assets used in operations when indicators of impairment are present
and the undiscounted cash flows estimated to be generated by those assets are
less than the assets' carrying value. Statement No. 121 also addresses the
accounting for long-lived assets that are expected to be disposed of. The
Company will adopt Statement 121 in the first quarter of the year ending June
30, 1997 ("Fiscal 1997") as required and, based on current circumstances, does
not believe the effect, if any, of adoption will be material.
 
     In Fiscal 1997, the Company is also required to adopt Statement No. 123,
Accounting for Stock Based Compensation ("SFAS No. 123"). As permitted by SFAS
No. 123, the Company will continue to account for stock based compensation with
its employees, directors, and consultants pursuant to Accounting Board Opinion
No. 25, Accounting for Stock Issued to Employees. The Company grants stock
options for a fixed rate of shares with an exercise price equal to the fair
value of the shares at the date of grant and accordingly recognizes no
compensation expense for the stock option grants. SFAS No. 123 requires
companies which do not choose to account for the effects of stock based
compensation in the financial statements to disclose in the Company's Notes to
the Consolidated Financial Statements the pro forma effects on earnings and
earnings per share as if such accounting had occurred. The Company will adopt
SFAS No. 123 in the first quarter of Fiscal 1997.
 
NOTE 3.  DEBT
 
     Upon the Company's relocation to Arizona, the Company entered into a note
from the Commerce and Economic Development Commission in the amount of
approximately $131,000 bearing interest at a rate of 6.5% due in installments
through June 2, 2000. At June 30, 1996, $126,580 was outstanding on the note.
 
     On June 3, 1996, the Company obtained a revolving line of credit facility
of up to $5 million from Norwest Bank Arizona, N.A ("Norwest"). The facility may
be drawn upon by the Company at its discretion and is collateralized by
substantially all of the assets of the Company. The outstanding balance of the
credit facility bears interest at a floating rate of 1.25% above Norwest's prime
rate per annum and expires in June 1997. The Agreement requires the Company to
comply with certain covenants, including covenants relating to the Company's
financial condition and results of operation. The Company has not drawn on this
credit facility.
 
                                      F-10
<PAGE>   44
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
NOTE 4.  INVESTMENT
 
     The consolidated financial statements for Fiscal 1994 include the accounts
and operations of Dyad, a then majority owned development stage enterprise.
Accordingly, net losses from the operations of Dyad amounting to approximately
$862,000 are included in net income in Fiscal 1994, partly offset by the
minority share in the losses of Dyad of $677,000. The sale of the Company's
interest in Dyad in Fiscal 1995 resulted in a gain of approximately $106,000. As
a result of the disposition of the Dyad Shares, the Company's and Dyad's
financial statements are not consolidated subsequent to June 30, 1994. The sale
contained provisions for possible additional consideration to the Company;
however, the amount to be received, if any, is uncertain.
 
NOTE 5.  COMMITMENTS AND CONTINGENCIES
 
OCCUPANCY ARRANGEMENTS
 
     The Company presently occupies approximately 12,150 square feet of office
space, at an average annual expense of $191,007 per annum, under a lease
agreement which expires in May 2005. The lease contains certain rent escalation
clauses and upon expiration can be renewed for a period of five years. Rent
expense was approximately $207,000, $188,000 and $314,000 for Fiscal 1996, 1995
and 1994, respectively.
 
RESEARCH AND DEVELOPMENT AND CONSULTING CONTRACTS
 
     The Company has in the past and may in the future enter into agreements
with various research organizations and individuals under which the Company
acquires certain patent and marketing rights for therapeutics developed under
such agreements in exchange for providing funding for collaborative research. It
is also anticipated that, before any commercial marketing can be commenced, the
Company will be required to secure certain regulatory approvals on the
technological processes involved.
 
     The Company has various consulting agreements with certain scientists in
exchange for the assignment of certain rights and consulting services. In
addition, the Company has granted options to purchase shares of Class A Common
Stock which are included in the stock option plan described in Note 8. These
options vest annually over the commitment periods. At June 30, 1996, the Company
had approximately $870,000 (solely attributable to the Chairman of the Central
Research Committee of the Company) of commitments payable over the remaining
five years under an agreement, which is cancelable by either party under certain
conditions.
 
LICENSING, MARKETING AND MANUFACTURING AGREEMENTS
 
     The Company has entered into licensing and marketing agreements under which
it has obtained rights to market certain existing and future pharmaceutical
products. Generally, the terms of such agreements vary, but range from 10 to 20
years from the date of the first sale of the related product or until the
expiration of the patent applicable to the product. The agreements provide for
varying royalties with certain stated minimum annual amounts, which vary by
agreement from $17,500 to, for one such agreement, $55,000. A commitment to pay
a minimum annual royalty of $160,000 commences twelve months after the United
States Food and Drug Administration grants approval to market the product
governed by the agreement. Total minimum royalties required to be paid on
products currently being sold approximate $72,500 per year.
 
                                      F-11
<PAGE>   45
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
OTHER
 
     The Company and certain of its subsidiaries are parties to other actions
and proceedings incident to their business. Liability in the event of final
adverse determinations in any of these matters is either covered by insurance
and/or established reserves, or, in the opinion of management, after
consultation with counsel, should not, in the aggregate, have a material adverse
effect on the consolidated financial position or results of operations of the
Company.
 
NOTE 6.  INCOME TAXES
 
     Deferred income taxes reflect the net tax effects of temporary differences
between the carrying amounts of assets and liabilities for financial reporting
purposes and the amounts used for income tax purposes. Significant components of
the Company's net deferred tax assets are as follows:
 
<TABLE>
<CAPTION>
                                                                         JUNE 30,
                                                                ---------------------------
                                                                   1996            1995
                                                                -----------     -----------
    <S>                                                         <C>             <C>
    Deferred tax assets:
      Net operating loss carryforwards........................  $10,500,000     $13,000,000
      Reserves................................................      700,000         630,000
      Research and experimentation credits....................      450,000         450,000
      Alternative Minimum Tax credits.........................       70,000              --
                                                                -----------     -----------
                                                                 11,720,000      14,080,000
    Deferred tax liabilities:
      Tax over book amortization of intangible assets related
         to ESOTERICA products acquisition....................     (120,000)       (120,000)
                                                                -----------     -----------
    Net deferred tax assets available.........................   11,600,000      13,960,000
    Less valuation allowance..................................    8,600,000      13,960,000
                                                                -----------     -----------
    Deferred tax assets.......................................  $ 3,000,000     $        --
                                                                ===========     ===========
</TABLE>
 
     At June 30, 1996, a valuation allowance of $8,600,000 has been recorded.
The valuation allowance decreased by $5,360,000 and $540,000 during Fiscal 1996
and 1995, respectively. Of the decrease in Fiscal 1996, $1,280,000 related to
the utilization of net operating loss carryforwards due to Fiscal 1996 taxable
income, $1,067,000 as a direct credit to equity for Fiscal 1996 tax deductions
related to stock option exercises, $1,080,000 for lower estimated deferred tax
rates based on the Company's relocation, and an additional $1,933,000 with
respect to changes in estimate with respect to the deferred tax assets that are
more likely than not expected to be recovered through future income. In Fiscal
1995, the decrease was as a result of decreases in net deferred tax assets due
to the utilization of net operating loss carryforwards.
 
     During the fourth quarter of Fiscal 1996, the Company reevaluated the
estimated amount of valuation allowance required to reduce deferred tax assets
in accordance with SFAS No. 109 to an amount management believes appropriate.
Accordingly, a credit to deferred tax benefit of $1,933,000 was reflected in the
consolidated income statement. The amount of net deferred tax assets, estimated
to be recoverable, was based upon management's assessment of the likelihood of
near-term operating income coupled with the uncertainties with respect to the
impact of future competitive and market conditions. The amount of deferred tax
assets available that will be ultimately realized will depend upon future events
which are uncertain.
 
     At June 30, 1996, the Company had net operating loss carryforwards for
federal income tax purposes of approximately $26,000,000 and research and
experimentation credits of approximately
 
                                      F-12
<PAGE>   46
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
$450,000, which begin expiring in varying amounts in the years 2005 through 2010
if not previously utilized. During Fiscal 1996, the Company incurred
approximately $70,000 in Alternative Minimum Tax which is available as a future
tax credit. The Alternative Minimum Tax credits do not expire for income tax
purposes.
 
     Components of the provision for income taxes (benefit) are as follows:
 
<TABLE>
<CAPTION>
                                                      YEAR ENDED JUNE 30,     YEAR ENDED JUNE 30,
                                                             1996                    1995
                                                      -------------------     -------------------
    <S>                                               <C>                     <C>
    Current
      Federal.......................................      $    70,000               $35,000
      State.........................................           37,000                25,000
                                                          -----------               -------
                                                              107,000                60,000
    Deferred
      Federal.......................................       (1,500,000)                   --
      State.........................................         (433,000)                   --
                                                          -----------               -------
                                                           (1,933,000)                   --
                                                          -----------               -------
              Total.................................      $(1,826,000)              $60,000
                                                          ===========               =======
</TABLE>
 
     Income tax expense (benefit) for the three years ended June 30, 1996, 1995,
and 1994 differs from the amount computed applying the federal statutory rates
due to the following:
 
<TABLE>
<CAPTION>
                                                                        JUNE 30,
                                                              -----------------------------
                                                              1996        1995        1994
                                                              -----       -----       -----
    <S>                                                       <C>         <C>         <C>
    Statutory federal income tax rate.......................   34.0%       34.0%       34.0%
    State tax rate..........................................    6.0        10.0        10.0
    Utilization of net operating loss carryforwards.........  (38.0)      (43.2)      (65.6)
    Change in estimate valuation allowance..................  (32.0)         --          --
    Losses of Dyad not generating tax benefit...............     --          --        13.5
    Other...................................................     --         2.8         8.1
                                                              -----       -----       -----
    Expense (benefit).......................................  (30.0%)       3.6%         --
                                                              =====       =====       =====
</TABLE>
 
NOTE 7.  STOCK TRANSACTIONS
 
     Class A Common Stock has one vote per share and Class B Common Stock has
ten votes per share. Each share of Class B Common Stock may be converted into
one share of Class A Common Stock at the option of the holder or, in some
circumstances, may automatically be converted upon a vote of the board of
directors and the majority of the Class B Common Stockholders. The Series B
Automatically Convertible Preferred Stock ("Series B Preferred Stock") was
issued as part of the 3-for-2 stock split described in this Note and has all the
relative rights, preferences, privileges and limitations of the Company's Class
B Common Stock and has no liquidation preferences or stated dividend rates. Each
share of Series B Preferred Stock shall be automatically converted into one
share of Class B Common Stock immediately upon approval of the Company's
shareholders of an amendment to the Company's Certificate of Incorporation
increasing the number of authorized shares of Class B Common Stock by a number
equal to or greater than the number of outstanding and issued shares of Series B
Preferred Stock. In addition, shares of Series B Preferred Stock are convertible
into Class A Common Stock on the same terms and conditions applicable to the
conversion of Class B Common Stock into Class A Common Stock.
 
                                      F-13
<PAGE>   47
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
     Pursuant to a Subscription Agreement, dated as of November 17, 1994, (the
"Subscription Agreement") with Frost Nevada Limited Partnership, a Nevada
limited partnership ("Frost Nevada"), the Company issued 235,714 shares of its
Class A Common Stock, $0.014 par value to Frost Nevada for a purchase price of
$600,600. The 235,714 shares of Class A Common Stock issued by the Company were
sold to Frost Nevada as part of a two-part transaction in which Frost Nevada
purchased an aggregate of 342,856 shares of Class A Common Stock. Pursuant to a
Stock Purchase Agreement dated as of November 17, 1994, (the "Stock Purchase
Agreement") between the Chairman of the Company and Frost Nevada, Frost Nevada
purchased from the Chairman 107,142 shares of Class A Common Stock.
 
     On August 17, 1995, the Board of Directors adopted a Preferred Stock
Purchase Rights plan and declared a dividend of one preference share purchase
right for each outstanding share of Class A Common Stock and Class B Common
Stock. Under certain circumstances, after a person has acquired beneficial
ownership of 15% of the Class A Common Stock, each Preference Stock Purchase
Right will entitle the holder to purchase, at the Right's then-current exercise
price, stock of the Company or its successor at a discount.
 
     On August 29, 1995, the Executive Committee of the Board of Directors
declared a one-for-fourteen reverse stock split which was approved by
shareholders on October 23, 1995. As a result of the reverse stock split, the
Company's outstanding shares decreased from approximately 61.0 million to
approximately 4.3 million at that date. Per share amounts and the average number
of shares outstanding at that date were retroactively revised for all periods
presented.
 
     Subsequent to year end, on July 22, 1996, the Board of Directors declared a
3-for-2 stock split effected in the form of a 50% stock dividend payable August
2, 1996, to common shareholders of record at the close of business on July 22,
1996. As a result of the stock split, the Company's outstanding shares increased
from approximately 4.5 million to 6.8 million. Per share amounts and the
weighted average number of shares outstanding have been retroactively revised
for all periods presented.
 
NOTE 8.  STOCK OPTION PLANS
 
     The Company has four Stock Option Plans ("the 1988, 1990, 1992 and 1995
Plans" or collectively, the "Plans") under which options may be granted for the
benefit of certain key employees, non-employee directors, and consultants of the
Company. The 1988, 1990, 1992 and 1995 Plans, as amended, provide originally for
the granting of a maximum of 321,429, 428,571, 535,714, and 535,714
respectively, qualified incentive stock options and non-qualified stock options,
to purchase Class A Common Stock of the Company. On July 22, 1996, the Board of
Directors authorized the granting of 201,474 shares to employees and consultants
at fair market value and has placed limitations on the number of shares
available for grant under the plans in the future. The Plans allow the Company
to designate options as qualified incentive or non-qualified on an as needed
basis.
 
     Qualified and non-qualified stock options vest over a period determined at
the time the options are granted ranging from one to five years, except for
certain non-qualified stock options that vest immediately. In April 1996, the
Plans were amended to provide for acceleration of vesting in the event of a
change in control of the Company. The options are generally granted at the fair
market value on the date of the grant and are exercisable at prices from $1.77
to $31.83, with a weighted average of $6.93 at June 30, 1996. In September 1995,
the Company approved the repricing of certain options under the Plans to
purchase 300,726 shares of Class A Common Stock previously exercisable at a
weighted average option exercise price of $10.85 per share to an exercise price
of $4.39 per share, which was the fair market value of the Class A Common Stock
at the date of repricing. The Company
 
                                      F-14
<PAGE>   48
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
has not previously repriced any of its stock options. Options for the year were
exercised at prices from $1.77 to $20.44. Information as to the options for
Fiscal 1994, 1995 and 1996 is as follows:
 
<TABLE>
<CAPTION>
                                           QUALIFIED     NON-QUALIFIED      TOTAL       EXERCISABLE
                                           ---------     -------------     --------     -----------
    <S>                                    <C>           <C>               <C>          <C>
    Balance at June 30, 1993.............    279,676         398,052        677,728       459,312
                                                                                          =======
    Granted..............................     85,019          87,054        172,073
    Terminated/expired...................    (39,983)         (4,286)       (44,269)
                                            --------        --------       --------
    Balance at June 30, 1994.............    324,712         480,820        805,532       587,589
                                                                                          =======
    Granted..............................    188,695         326,213        514,908
    Terminated/expired...................   (240,381)       (226,682)      (467,063)
                                            --------        --------       --------
    Balance at June 30, 1995.............    273,026         580,351        853,377       524,481
                                                                                          =======
    Granted..............................    211,311         298,709        510,020
    Exercised............................    (25,672)       (117,880)      (143,552)
    Terminated/expired...................   (131,973)       (221,972)      (353,945)
                                            --------        --------       --------
    Balance at June 30, 1996.............    326,692         539,208        865,900       250,455
                                            ========        ========       ========       =======
</TABLE>
 
The table includes 90,716 shares of Common Stock that will be available to
certain employees relating to the stock split described in Note 7 upon
authorization of additional shares by the Company's shareholders.
 
     During Fiscal 1996, 128,568 of non-qualified stock options not subject to
the stock option plans have been exercised by outside parties at $14.56. An
additional 47,121 non-qualified stock options not subject to the plans are
issued and outstanding to outside parties at June 30, 1996 with exercise price
ranges of $14.56 to $28.00. During Fiscal 1996, 45,355 warrants were exercised
at $4.67. At June 30, 1996, there were no outstanding warrants.
 
NOTE 9.  SIGNIFICANT CUSTOMERS
 
     For Fiscal 1996, three customers accounted for approximately 15.5%, 12.2%,
and 11.8% of sales. For Fiscal 1995, two customers accounted for approximately
15.9% and 9.6% of sales. For Fiscal 1994, two customers accounted for
approximately 15.1% and 11.2% of sales.
 
NOTE 10.  FINANCIAL INSTRUMENTS -- CONCENTRATIONS OF CREDIT RISK
 
     Financial instruments which potentially subject the Company to significant
concentrations of credit risk consist principally of cash and cash equivalents
and accounts receivable.
 
     The Company maintains cash and cash equivalents primarily with two
financial institutions that invest funds in short-term, interest bearing,
investment grade, marketable securities. The Company performs periodic
evaluations of the relative credit standing of these financial institutions.
 
     At June 30, 1996 and 1995, five and six customers, respectively, comprised
approximately 55.2% and 48.8%, respectively, of accounts receivable. The Company
does not require collateral from its customers but performs periodic credit
evaluations of its customers' financial condition. Management does not believe
significant credit risk exists at June 30, 1996.
 
                                      F-15
<PAGE>   49
 
                       MEDICIS PHARMACEUTICAL CORPORATION
 
           NOTES TO CONSOLIDATED FINANCIAL STATEMENTS -- (CONTINUED)
 
NOTE 11.  DEFINED CONTRIBUTION PLAN
 
     The Company has a defined contribution plan (the "Plan") that is intended
to qualify under Section 401(k) of the Internal Revenue Code. All employees,
except those with less than three months of service and those who have not
attained the age of 21, are eligible to participate in the Contribution Plan.
Participants may contribute, through payroll deductions, up to 20% of their
basic compensation, not to exceed Internal Revenue Code limitations. Although
the Contribution Plan provides for profit sharing contributions by the Company,
the Company has not made any such contributions since its inception.
 
NOTE 12.  QUARTERLY FINANCIAL INFORMATION (UNAUDITED)
 
     In the table below is the quarterly financial information for Fiscal 1996
and 1995. (All figures are in thousands except per share data).
 
<TABLE>
<CAPTION>
                                                     FISCAL YEAR ENDED JUNE 30, 1996
                                                        (FOR THE QUARTERS ENDED)
                                 -----------------------------------------------------------------------
                                 SEPTEMBER 30, 1995   DECEMBER 31, 1995   MARCH 31, 1996   JUNE 30, 1996
                                 ------------------   -----------------   --------------   -------------
    <S>                          <C>                  <C>                 <C>              <C>
    Net sales..................        $4,574              $ 6,449            $7,016          $ 7,271
    Gross profit...............         3,257                4,667             5,040            5,390
    Net income.................           646                1,404             1,759            4,071
    Net income per share.......          0.10                 0.21              0.24             0.54
</TABLE>
 
<TABLE>
<CAPTION>
                                                     FISCAL YEAR ENDED JUNE 30, 1995
                                                        (FOR THE QUARTERS ENDED)
                                 -----------------------------------------------------------------------
                                 SEPTEMBER 30, 1994   DECEMBER 31, 1994   MARCH 31, 1995   JUNE 30, 1995
                                 ------------------   -----------------   --------------   -------------
    <S>                          <C>                  <C>                 <C>              <C>
    Net sales..................        $3,690              $ 4,725            $5,033          $ 5,684
    Gross profit...............         2,519                3,024             3,659            4,080
    Net income.................            26                  308               312              967
    Net income per share.......            --                 0.05              0.05             0.14
</TABLE>
 
     The quarterly net income per share data disclosed above does not agree with
the amounts reported in the Company's Quarterly Reports on Form 10-Q filed with
the Securities and Exchange Commission as the amounts have been revised to
reflect the stock splits discussed in Note 7 and for certain reclassification
made to conform with fourth quarter presentation. The net income for the quarter
ended June 30, 1996 includes a fourth quarter adjustment to record deferred
income tax benefits of $1,933,000 as described in Note 6.
 
                                      F-16
<PAGE>   50
SCHEDULE II - VALUATION AND QUALIFYING ACCOUNTS



<TABLE>
<CAPTION>
                                      Balance at          Charged to           Charged to                              Balance at
        Description                beginning of year  costs and expenses     other accounts        Deductions          end of year
- ---------------------------------  -----------------  ------------------     --------------        ----------          -----------

<S>                                <C>                <C>                    <C>                   <C>                 <C> 
Year Ended June 30, 1996
   Deducted from Asset Accounts:
   Accounts Receivable:
     Allowances                    $         520,000  $           50,000     $      160,000                            $   680,000

Year Ended June 30, 1995
   Deducted from Asset Accounts:
   Accounts Receivable:
     Allowances                    $         400,000                         $      120,000                            $   520,000

Year Ended June 30, 1994
   Deducted from Asset Accounts:
   Accounts Receivable:
  Allowances                       $         240,000                         $      160,000                            $   400,000

</TABLE>

 Draft August 14, 1996 (10:53am) 

                                      S-1


<PAGE>   51
 
                               POWER OF ATTORNEY
 
     KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears
below constitutes and appoints Jonah Shacknai and Mark A. Prygocki, Sr., or
either of them, as his true and lawful attorneys-in-fact and agents, with full
power of substitution and resubstitution, for him and in his name, place and
stead, in any and all capacities, to sign any and all amendments to this Annual
Report on Form 10-K and any documents related to this report and filed pursuant
to the Securities and Exchange Act of 1934, and to file the same, with all
exhibits thereto, and other documents in connection therewith, with the
Securities and Exchange Commission, granting unto said attorneys-in-fact and
agents, full power and authority to do and perform each and every act and thing
requisite and necessary to be done in connection therewith as fully to all
intents and purposes as he might or could do in person, hereby ratifying and
confirming all that said attorneys-in-fact and agents, or their substitute or
substitutes may lawfully do or cause to be done by virtue hereof.
 
                                   SIGNATURES
 
     Pursuant to the requirements of Section 13 or 15(d) of the Securities
Exchange Act of 1934, the Registrant has duly caused this report to be signed on
its behalf by the undersigned, thereunto duly authorized.
 
Date: August 15, 1996
 
                                        MEDICIS PHARMACEUTICAL CORPORATION
 
                                        By: /s/ JONAH SHACKNAI
 
                                           -------------------------------------
                                           Jonah Shacknai
                                           Chairman of the Board of Directors
                                           and Chief Executive Officer
 
     Pursuant to the requirements of the Securities Exchange Act of 1934, this
report has been signed below by the following persons on behalf of the
Registrant in the capacities and on the dates indicated.
 
<TABLE>
<CAPTION>
              SIGNATURE                                TITLE                         DATE
- -------------------------------------  --------------------------------------  ----------------
<S>                                    <C>                                     <C>
/s/ JONAH SHACKNAI                     Chairman of the Board of Directors      August 15, 1996
- -------------------------------------  and Chief Executive Officer
Jonah Shacknai                         (Principal Executive Officer)

/s/ MARK A. PRYGOCKI, SR.              Chief Financial Officer                 August 15, 1996
- -------------------------------------  (Principal Financial and Accounting
Mark A. Prygocki, Sr.                  Officer)

/s/ JOSEPH SALVANI                     Director                                August 15, 1996
- -------------------------------------
Joseph Salvani

/s/ RICHARD L. DOBSON, M.D.            Director                                August  , 1996
- -------------------------------------
Richard L. Dobson, M.D.

/s/ MICHAEL A. PIETRANGELO             Director                                August 15, 1996
- -------------------------------------
Michael A. Pietrangelo

                                       Director                                August 15, 1996
- -------------------------------------
Philip S. Schein, M.D.

/s/ ARTHUR ALTSCHUL, JR.               Director                                August 15, 1996
- -------------------------------------
Arthur Altschul, Jr.

/s/ LOTTIE SHACKELFORD                 Director                                August 15, 1996
- -------------------------------------
Lottie Shackelford
</TABLE>
 
                                       34
<PAGE>   52


<PAGE>   1
                                                                    EXHIBIT 10.9


                              EMPLOYMENT AGREEMENT

         THIS AGREEMENT is made as of this 24th day of July 1996 between MEDICIS
PHARMACEUTICAL CORP., a corporation organized under the laws of the State of
Delaware (the "Company") with offices located at 4343 East Camelback Road,
Phoenix, Arizona, and Jonah Shacknai (the "Executive"), residing at 5868 East
Berneil Lane, Paradise Valley, Arizona:

                                   WITNESSETH:

         WHEREAS, the Company and the Executive desire to enter into the present
Agreement whereby the Executive will continue to provide personal services to
the Company as Chairman and Chief Executive officer; and

         WHEREAS, in its business, the Company has developed and uses valuable
technical and nontechnical information including information relating to
development, use, manufacture and marketing of certain biologically-active
compounds, and it is necessary for the Company to protect certain of the
information either by patents, copyrights, or by holding it secret or
confidential; and

         WHEREAS, the aforesaid information is vital to the success of the
Company's business, and the Executive through his activities
<PAGE>   2
                                                                               2

may become acquainted therewith, and may contribute thereto, either through
research, inventions, discoveries or otherwise; and

         WHEREAS, in the course of his employment, the Executive has gained and
will gain knowledge of the business affairs, finances, management, marketing
programs and philosophy, customers and methods of operation of the Company; and

         WHEREAS, the Company would suffer irreparable harm if the Executive
were to use such knowledge, information and business acumen in competition with
the Company,

         NOW, THEREFORE, in consideration of the continued employment of
Executive by the Company as Chairman and Chief Executive Officer, the above
premises and the mutual agreements hereinafter set forth, the receipt, adequacy
and sufficiency of which is hereby acknowledged, the parties agree as follows:

         1.       Definitions.

                  (a) "Business of the Company" shall mean and include the
business of developing, manufacturing, marketing, selling and using certain
chemical compounds for use in the dermatologic industry or such other businesses
as the Company derived substantial revenues from, which revenues exceed twenty
(20%) percent of the Company's gross annual revenues in the Company's most
recent fiscal year.

                  (b) "Competing Business" shall mean any business which is the
same or essentially the same as the Business of the Company.
<PAGE>   3
                                                                               3

                  (c) "Confidential Information" shall mean all non public
customer lists, sales and marketing information, customer account records,
training and operations material and memoranda, trade secrets, strategic
planning materials and information product development plans, scientific and
technical information, personnel records, pricing information, and financial
information concerning or relating to the business, accounts, customers,
employees and affairs of the Company, obtained by or furnished, disclosed or
disseminated to the Executive, or obtained, assembled or compiled by the
Executive or under his supervision during the course of his employment by the
Company, and all physical embodiments of the foregoing, all of which are hereby
agreed to be the property of and confidential to the Company, but Confidential
Information shall not include any of the foregoing to the extent the same is or
becomes publicly known through no fault or breach of this Agreement by the
Executive.

         2.       Terms of Employment; Duties.

                  (a) The Company employs the Executive as Chairman of the Board
of Directors of the Company, and Chief Executive Officer of the Company, and the
Executive accepts such employment with the Company in that capacity subject to
the terms and conditions hereof. The Executive shall in such office have the
responsibilities which include presiding over and participating in deliberations
of the Board as its Chairman and as a member of the Board;
<PAGE>   4
                                                                               4

serving on the Executive Committee of the Board; exercising ultimate
responsibility on a reporting basis for sales, marketing, research and
development, operations, regulatory compliance, finance, personnel, corporate
development, public and shareholder relations and governmental relations
activities of the Company; exercising ultimate responsibility for strategic
planning and evaluation, and serving as Company's official spokesman and
representative in all matters.

                  (b) Throughout his employment hereunder, the Executive shall
devote substantially all of his time, energy and skill during regular business
hours to the performance of the duties of his employment (reasonable vacations,
reasonable absences due to illness, and reasonable time as may be necessary for
the Executive to manage his personal investments, excepted), shall faithfully
and industriously perform such duties, and shall diligently follow and implement
all management policies and decisions of the Company.

         3.       Compensation and Related Matters

                  (a) For his services hereunder, the Company shall pay to the
Executive the compensation and provide the benefits set forth in Exhibit A
attached hereto and incorporated herein as part of this Agreement and such
benefits as are otherwise provided for herein.
<PAGE>   5
                                                                               5

                  (b) The Executive shall be eligible to fully participate in
all present or future pension, retirement, medical, dental, disability, life
insurance or any other employee benefit plans of the Company, and in addition,
the Executive shall be eligible to fully participate in all present or future
incentive compensation, bonus, profit sharing, stock option or stock purchase
plans of the Company as and to the extent granted or approved and determined by
the Board of Directors of the Company, subject to the provisions of Exhibit A
hereof.

         4.       Term and Termination of This Agreement.

                  (a) The Executive's employment under this Agreement shall be.
for a period of five (5) years commencing on July 1, 1996 and expiring on June
30, 2001 ("the Initial Term"), which period shall automatically be extended
beyond its current five-year term, without further action by the parties, as of
June 30, 2001 and as of each succeeding five-year period thereafter, for another
five (5) year period beginning on July 1, 2001 and each succeeding five (5) year
period, unless either party shall have served written notice upon the other six
(6) months prior to June 30, 2001, or prior to June 30th of the expiration date
occurring on each succeeding five (5) year period thereafter, of its intention
to terminate or modify this Agreement, subject however to the earlier
termination thereof pursuant to the provisions of this Agreement. Should this
Agreement be automatically renewed for any five (5)
<PAGE>   6
                                                                               6

year period, the terms of said Agreement shall remain the same, except for any
increases in the salary, bonuses or benefits provided by the Company to the
Executive.

                  (b) The term of the Executive's employment hereunder may be
terminated prior to the expiration of the Initial Term (or any extension or
automatic renewal thereof) in the following events:

                           (i)   termination by mutual agreement of the parties;

                           (ii)  termination by the Company without cause upon
                                 sixty (60) days' written notice to the
                                 Executive, as provided for in Section
                                 5(a)(iii);

                           (iii) termination upon the Executive's death or
                                 disability as defined in and as provided for in
                                 Section 5(a)(v);

                           (iv)  termination of the Executive for cause, as
                                 provided for in Sections 5(a)(ii) and 7;

                           (v)   resignation by the Executive for good reason,
                                 as provided for in Sections 5(a)(iii) and 8;
<PAGE>   7
                                                                               7

                           (vi)  termination of the Executive arising as a
                                 result of change in ownership or control, as
                                 provided for in Sections 5(a)(iii) and 9; or

                           (vii) voluntary resignation by the Executive for
                                 reasons other than those falling within
                                 paragraph (i), (v) or (vi) herein.

         5.       Payments Upon Termination

                  (a)      In the event that the Executive's employment
                           hereunder is terminated pursuant to Section 4(b)
                           above, the Company shall pay to Executive the
                           following amounts within thirty (30) days of such
                           termination or as otherwise set forth below:

                           (i)    If the Executive's employment is terminated
                                  pursuant to subsection 4(b)(i), the Company
                                  shall pay to the Executive all amounts owing
                                  to the Executive as Annual Compensation
                                  through the Date of Termination (as defined
                                  herein), consisting of Base Salary through
                                  the end of the calendar month from the Date
                                  of Termination and a pro rata bonus based
                                  upon the Executive's prior year's bonus.
<PAGE>   8
                                                                            8

                           (ii)   If the Executive's employment is terminated
                                  by the Company for Cause (as defined in
                                  Section 7 herein) pursuant to subsection
                                  4(b)(iv), or if the Executive voluntarily
                                  resigns his employment pursuant to Section
                                  4(b)(vii), the Company shall pay to the
                                  Executive all amounts owing to the Executive
                                  as Base Salary through the end of the
                                  calendar month of the Date of Termination.

                           (iii)  (a)  If the Executive's employment is      
                                       terminated by the Company without   
                                       cause (Section 4(b)(ii)), or in the 
                                       event of the termination of this    
                                       Employment Agreement pursuant to    
                                       Section 4(b)(v) and Section 8       
                                       herein (Resignation by Executive    
                                       For Good Reason), or in the event   
                                       the Company shall terminate this    
                                       Employment Agreement for any reason 
                                       other than pursuant to Section      
                                       4(a)(iv) (cause) or Section         
                                       4(a)(iii) (death or disability), or
                                       Section 4(b)(vi) and Section 9   
                                       (Termination of Employment as a     
                                       Result of Change In Ownership or    
                                       Control):                           
<PAGE>   9
                                                                               9

                                            --       the Company shall pay the
                                                     Executive his then current
                                                     annual compensation, and a
                                                     pro rata bonus based on the
                                                     Executive's prior year's
                                                     bonus, through the Date of
                                                     Termination.

                                            --       in lieu of any further
                                                     salary payments to the
                                                     Executive for periods
                                                     subsequent to the Date of
                                                     Termination, the Company
                                                     shall pay as severance to
                                                     the Executive on the fifth
                                                     day following the Date of
                                                     Termination, a lump sum
                                                     payment equal to the number
                                                     of months remaining from
                                                     the date of termination
                                                     until the expiration date
                                                     of this Employment
                                                     Agreement, or any renewal
                                                     thereof, divided by twelve
                                                     (12), times the sum of (a)
                                                     the Executive's annual Base
                                                     Salary at the highest rate
                                                     in effect during the twelve
                                                     (12) months immediately
                                                     preceding the Date of
                                                     Termination and (b) the
                                                     average of the annual bonus
                                                     payments, if any, paid to
                                                     the Executive in the
                                                     preceding three (3) years,
                                                     however in
<PAGE>   10
                                                                              10

                                                     no event shall the amount
                                                     of severance to be paid to
                                                     the Executive be less than
                                                     the amount of payment in
                                                     the event of non renewal of
                                                     the Employment Agreement,
                                                     as provided for in
                                                     paragraph 6 of this
                                                     Agreement, i.e. a lump sum
                                                     payment equal to (i) two
                                                     (2) times the sum of (A)
                                                     the Executive's annual Base
                                                     Salary at the highest rate
                                                     in effect during the twelve
                                                     (12) months immediately
                                                     preceding the Date of
                                                     Termination and (B) the
                                                     average of the Annual bonus
                                                     payments, if any, paid to
                                                     the Executive in the
                                                     preceding three (3) years;
                                                     and (ii) an additional
                                                     amount equal to 1/24 of the
                                                     lump sum payment provided
                                                     in clause (i), above,
                                                     multiplied by each full
                                                     year of the Executive's
                                                     service with the Company.

                                            --       the Company shall pay all 
                                                     other damages to which the
                                                     Executive may be entitled 
                                                     as a result of the
                                                     Company's termination of
                                                     his
<PAGE>   11
                                                                              11

                                                     employment under this
                                                     Agreement, except for
                                                     Cause, including damages
                                                     for any and all loss of
                                                     benefits to the Executive
                                                     under the employee benefit
                                                     plans which he would have
                                                     received had this Agreement
                                                     not been terminated for
                                                     reasons set forth in
                                                     subsections 4(b)(ii)
                                                     4(b)(v) and 4(b)(vi),
                                                     herein, and had the
                                                     Executive's employment
                                                     continued for the full
                                                     Initial Term, or for the
                                                     full period of any
                                                     extension or automatic
                                                     renewal, and including all
                                                     legal fees and expenses
                                                     incurred by the Executive
                                                     in contesting or disputing
                                                     any such termination or in
                                                     seeking to obtain or
                                                     enforce any right or
                                                     benefit provided by this
                                                     Employment Agreement.

                           (iii)(b)         In the event of the termination of
                                            this Employment Agreement pursuant
                                            to Section 4(b)(vi) and Section 9
                                            herein (Termination of Employment as
                                            a Result of Change In Ownership Or
                                            Control):
<PAGE>   12
                                                                              12

                                            --       the Company shall pay the
                                                     Executive his then current
                                                     annual compensation, and a
                                                     pro rata bonus based on the
                                                     Executive's prior year's
                                                     bonus, through the Date of
                                                     Termination.

                                            --       in lieu of any further
                                                     salary payments to the
                                                     Executive for periods
                                                     subsequent to the Date of
                                                     Termination, the Company
                                                     shall pay as severance to
                                                     the Executive on the fifth
                                                     day following the Date of
                                                     Termination, a lump sum
                                                     payment equal to 4 times
                                                     the sum of (a) the
                                                     Executive's annual Base
                                                     Salary at the highest rate
                                                     in effect during the twelve
                                                     (12) months immediately
                                                     preceding the Date of
                                                     Termination and (b) the
                                                     average of the annual bonus
                                                     payments, if any, paid to
                                                     the Executive in the
                                                     preceding three (3) years;
                                                     and

                                            --       the Company shall pay all 
                                                     other damages to which the
                                                     Executive may be entitled 
                                                     as a result of the
<PAGE>   13
                                                                              13

                                                     Company's termination of
                                                     his employment under this
                                                     Agreement, except for
                                                     Cause, including damages
                                                     for any and all loss of
                                                     benefits to the Executive
                                                     under the employee benefit
                                                     plans which he would have
                                                     received had this Agreement
                                                     not been terminated for
                                                     reasons set forth in
                                                     subsections 4(b)(ii)
                                                     4(b)(v) and 4(b)(vi),
                                                     herein, and had the
                                                     Executive's employment
                                                     continued for the full
                                                     Initial Term, or for the
                                                     full period of any
                                                     extension or automatic
                                                     renewal, and including all
                                                     legal fees and expenses
                                                     incurred by the Executive
                                                     in contesting or disputing
                                                     any such termination or in
                                                     seeking to obtain or
                                                     enforce any right or
                                                     benefit provided by this
                                                     Employment Agreement.

                           (iv)   If Executive's employment is terminated
                                  pursuant to subsection 4(b)(iii) by reason
                                  of Executive's death, the Company agrees to
                                  pay to the legal representative of his
                                  estate, (i) for a period of twelve (12)
                                  months
<PAGE>   14
                                                                           14

                                  (commencing with the Date of Termination)
                                  an amount equal to and payable at the same
                                  rate at his then current Base Salary, and
                                  (ii) any payment the Executive's spouse,
                                  beneficiaries, or estate may be entitled to
                                  receive pursuant to any pension or employee
                                  benefit plan or life insurance policy
                                  presently maintained by the Company.

                           (v)    During any period that the Executive fails to
                                  perform his duties hereunder as a result of
                                  incapacity due to his physical or mental or
                                  emotional illness, the Executive shall
                                  continue to receive his full Base Salary
                                  along with any bonus payments awarded by the
                                  Board of Directors until the Executive
                                  returns to his duties or until his employment
                                  is terminated for reason of disability
                                  pursuant to Section 4(b)(iii).

                                  "Disability" shall mean the inability of
                                  the Executive to perform the duties of
                                  Chairman and Chief Exchange Officer of the
                                  Company due to physical, mental or
                                  emotional incapacity or illness, where such
                                  inability is expected to result in death or
                                  to be of long-continued
<PAGE>   15
                                                                           15

                                  and indefinite duration, but in no event
                                  shall such duration be less than One
                                  Hundred Eighty (180) consecutive days. The
                                  determination of "Disability" shall be made
                                  by the Board of Directors of the Company
                                  ("the Board") and the Executive, as
                                  determined by an independent physician
                                  selected by both the Board and the
                                  Executive. In the event of such Disability,
                                  the Company may, at its election and by
                                  providing written notice thereof to the
                                  Executive within sixty (60) days after such
                                  determination, terminate the Executive's
                                  employment hereunder effective on the date
                                  set forth in such notice. If the Board or
                                  the Company does not timely give notice to
                                  the Executive of its election to terminate
                                  the Executive for such Disability, then the
                                  Company shall be deemed to have waived its
                                  right to terminate the Executive based upon
                                  such Disability.

                                  After such termination because of the
                                  Executive's disability, the Executive shall
                                  be paid, in substantially equal monthly
                                  installments, 100% of his Base Salary (at
                                  the rate in effect at the time Notice of
<PAGE>   16
                                                                              16

                                  Termination is given) for twelve (12)
                                  months, and thereafter an annual amount
                                  equal to 50% of such Base Salary for the
                                  balance of the Initial Term, but in no
                                  event for less than a second twelve (12)
                                  month period.

                  (b)      In no event shall any payment pursuant to this
                           Section 5 be made to the extent that it would
                           constitute an "excess parachute payment," as
                           defined in Section 280G of the Internal Revenue
                           Code of 1986.  Should any such payment provided for
                           in section 5 constitute an "excess parachute
                           payment" as defined in Section 280G of the Internal
                           Revenue Code of 1986, the Company and the Executive
                           shall meet in good faith to negotiate a substitute
                           payment to the Executive equal to that amount which
                           constitutes the excess parachute payment, the
                           payment of which amount is permissible under the
                           Internal Revenue Code and regulations promulgated
                           thereunder.

                  (c)      Unless the Executive is terminated for Cause pursuant
                           to Section 4(a)(iii) or voluntarily resigns his
                           employment pursuant to section 4(a)(vii), the Company
                           shall maintain in full force and effect, for the
                           continued benefit of the
<PAGE>   17
                                                                              17

                           Executive, for a period of four (4) years following
                           the Date of Termination all employee benefit plans
                           and programs in which Executive was entitled to
                           participate immediately prior to the Date of
                           Termination, provided that the Executive's continued
                           participation in such employee benefit plans is
                           possible under the general terms and provisions of
                           such plans and programs. In the event that the
                           Executive's participation in any such plan or program
                           is barred at any time during this four (4) year
                           period, the Company shall arrange to provide the
                           Executive with benefits substantially similar to
                           those which the Executive would otherwise have been
                           entitled to receive under such plans and programs
                           from which his continued participation is barred, or
                           alternatively, to provide to the Executive the
                           economic after-tax equivalent of the participation in
                           all of said employee benefit plans in which the
                           Executive's participation is barred. At the end of
                           the period of coverage, the Executive shall have the
                           option to have assigned to him at no cost and with no
                           apportionment of prepaid premiums any assignable
                           insurance policy owned by the Company which relate
                           specifically to the Executive.
<PAGE>   18
                                                                              18

                  (d)      (i) In addition to the foregoing, if the
                               Executive's employment is terminated by the
                               Company without cause pursuant to Section
                               4(b)(ii), upon the Executive's death or
                               disability pursuant to Section 4(b)(iii),
                               upon the Executive's resignation for good
                               reason pursuant to Section 4(b)(v), as a
                               result of a change in ownership or control
                               pursuant to Section 4(b)(vi), or upon the
                               nonrenewal of this Agreement on its expira-
                               tion date, all stock options awarded to the
                               Executive on or before the Date of
                               Termination under the Company's outstanding
                               Incentive Stock Option Plans; or issuable to
                               Executive under any future stock option plans
                               granted by the Company during the term of
                               this Agreement ("the Options"), shall immedi-
                               ately vest to the Executive's benefit or the
                               benefit of the Executive's estate, in the
                               event of his death.  Further, the Executive
                               shall retain the right to exercise his rights
                               under the options for the full term(s)
                               thereof, and the Company shall take all
                               actions as are necessary to transfer the
                               Options from the Company's qualified stock
                               option plan(s) to the Company's nonqualified
<PAGE>   19
                                                                              19

                               stock option plan(s) or such other plans as
                               may be applicable. The intent of this
                               provision is to insure that in the event of
                               termination of the Executive's employment
                               for reasons referenced in this subsection,
                               the Executive shall be fully vested in the
                               Options and shall have the full term of
                               each such option or options to exercise the
                               same.

                          (ii) In the event the Executive's employment is
                               terminated in accordance with Section
                               4(a)(vi) and, as a consequence of such change
                               in ownership or Control the Company's incen-
                               tive Stock option plans in existence at the
                               time of the Executive's termination of
                               employment cease to exist at any time before
                               the Executive's right to exercise the Options
                               pursuant to Section 5(d)(i) above has
                               expired, the Executive's right to the
                               Options, or to the receipt of cash compensa-
                               tion in lieu thereof, shall be governed by
                               the provisions of section 9(b)(ii), below.

                  (e)      The Executive shall not be required to mitigate the
                           amount of any payment provided for in this Section
                           5 by seeking other employment or otherwise, and no
<PAGE>   20
                                                                              20

                           compensation earned by the Executive after his
                           termination of employment with the Company shall be
                           applied to offset any payment provided for in this
                           Agreement.

                  (f)      Any termination of the Executive's employment by the
                           Company or by the Executive (other than termination
                           by reason of the Executive's death) shall be
                           communicated by written Notice of Termination to the
                           other party hereto in accordance with provisions set
                           forth in this Agreement.

                  (g)      "Date of Termination" shall mean:

                           (i)   if the Executive's employment is terminated
                                 by his death, the date of his death,

                           (ii)  if the Executive's employment is terminated
                                 by reason of the Executive's disability,
                                 sixty (60) days after Notice of Termination
                                 is given (provided that the Executive shall
                                 not have returned to the performance of his
                                 duties on a reasonable full-time basis
                                 during such sixty (60) day period),
<PAGE>   21
                                                                              21

                           (iii) if the Executive's employment is terminated
                                 for any other reason, the date specified in
                                 the Notice of Termination; provided that if
                                 within sixty (60) days after the Notice of
                                 Termination is given the party receiving such
                                 Notice of Termination notifies the other
                                 party that a dispute exists concerning the
                                 termination, the Date of Termination shall be
                                 the date on which said dispute is finally
                                 determined, either by mutual written agree-
                                 ment of the parties, or by a final arbitra-
                                 tion award as provided for in Section 18 (the
                                 time for appeal therefrom having expired and
                                 no appeal having been perfected).

         6.       Payment in the Event of Non Renewal of Agreement

                  (a) In the event this Agreement is not renewed by the Company
for a minimum period of three years after its expiration date of June 30, 2001,
the Company shall pay as severance to the Executive on the fifth day following
the Date of Termination, a lump sum payment equal to (i) two (2) times the sum
of (A) the Executive's annual Base Salary at the highest rate in effect during
the twelve (12) months immediately preceding the Date of Termination and (B) the
average of the annual bonus payments, if any, paid to the Executive in the
preceding three (3) years; and
<PAGE>   22
                                                                              22

(ii) an additional amount equal to 1/24 of the lump sum payment provided in
clause (i), above, multiplied by each full year of the Executive's service with
the Company.

                  (b) Upon the non renewal of this Agreement by the Company as
provided in Section 6(a) above, the Company shall maintain in full force and
effect for the continued benefit of the Executive for a period of two (2) years
following the Date of Termination all employee benefit plans and programs in
which the Executive was entitled to participate immediately prior to the Date of
Termination, provided that the Executive's continued participation in such
employee benefit plans is possible under the general terms and provisions of
such plans and programs. In the event that the Executive's participation in any
such plan or program is barred at any time during this two (2) year period, the
Company shall arrange to provide the Executive with benefits substantially
similar to those which the Executive would otherwise have been entitled to
receive under such plans and programs from which his continued participation is
barred, or alternatively, to provide to the Executive the economic after-tax
equivalent of the participation in all of said employee benefit plans in which
the Executive's participation is barred. At the end of the period of coverage,
the Executive shall have the option to have assigned to him at no cost and with
no apportionment of prepaid premiums any assignable insurance policy owned by
the Company which relates specifically to him.
<PAGE>   23
                                                                              23

                  (c) In the event of the non-renewal of the Company of this
Agreement as provided for in Section 6(a), above, all options awarded to the
Executive on or before the Date of Termination under the Company's outstanding
Incentive Stock option Plans, or issuable to Executive under any future stock
option plans established by the Company during the term of this Agreement, shall
immediately vest to the Executive's benefit and the Executive shall retain the
right to exercise his rights under the Options for the full term(s) thereof, and
the Company shall take all actions as are necessary to transfer the "Options"
from the Company's qualified stock option plan(s) to the Company's nonqualified
stock option plan(s) or such other plans as may be applicable.

         7.       Termination for Cause

                  (a) If the Company reasonably shall determine that there are
grounds for discharging the Executive for Cause (as hereinafter defined), the
Company may, through the Board, at its election within thirty (30) days
thereafter, give the Executive notice of its intention to terminate the
Executive for cause, stating the grounds for termination and specifying a date,
within thirty (30) days of such notice, on which the Executive shall be given an
opportunity to discuss such grounds for termination at a meeting of the Board.
<PAGE>   24
                                                                              24

                  (b) If the grounds for termination are those specified in
clause (ii), (iii) or (iv) of paragraph (d) hereof, at such Board meeting the
Board and the Executive shall discuss in good faith and shall determine and set
forth in writing what actions the Executive might take, and by what date, to
cure the material adverse impact or default, as the case may be, to the
reasonable satisfaction of the Board, but in no event earlier than sixty (60)
days after said meeting. When the Board and the Executive have agreed in writing
upon a cure and the date by which it shall be provided, the Board shall take no
further action regarding termination for cause on such grounds until such date,
and on such date it shall provide written notice to the Executive that either
(i) the cure has been satisfactorily provided, and the Board shall continue to
employ the Executive under this Agreement pursuant to the terms hereof, or (ii)
the cure has not been satisfactorily provided and the Board is terminating the
Executive's employment for cause effective immediately.

                  (c) If the grounds for termination are those specified in
clause (i) of paragraph (d) hereof, it is understood and agreed that no
satisfactory cure is available. If following discussion with the Executive of
the grounds for his termination (as specified in clause (i) of paragraph (d)
hereof, at the Board meeting the Board shall continue intent on discharging the
Executive for cause on such grounds, the Company shall provide written notice of
termination to the Executive within thirty (30) days of the date of
<PAGE>   25
                                                                              25

such meeting, and such termination shall be effective upon the date set forth in
such notice.

                  (d)      For purposes of this Agreement the term "cause"
shall mean:

                           (i)    the conviction of the Executive for a felony
                                  involving fraud or moral turpitude;

                           (ii)   The Executive's engaging in activities
                                  prohibited by Section 10 hereof;

                           (iii)  the Executive's frequent willful gross
                                  neglect (other than as a result of
                                  physical, mental or emotional illness) of
                                  his duties and responsibilities under this
                                  Agreement that has a material adverse
                                  impact on the business or reputation of the
                                  Company; or

                           (iv)   the Executive's willful gross misconduct that
                                  has a material adverse impact on the business
                                  or reputation of the Company.

                  (e) For each act or occurrence giving rise to a basis for
termination for cause, failure by the Company to timely give. all written
notices as set forth in this Section, from the date the
<PAGE>   26
                                                                              26

Board or any of its members were either (i) aware of such act or occurrence
giving rise to a basis for termination for cause, or (ii) with reasonable due
diligence should have known of such act or occurrence giving rise to a basis for
termination for cause, shall constitute a waiver of the Company's right to
terminate based upon such cause, but such waiver shall not prejudice the
Company's right to terminate pursuant to this Section based upon another act or
occurrence giving rise to a basis for termination for cause, whether of the same
or a different type.

         8.       Resignation by Executive for Good Reason

         In the event that the Company shall during the term of this contract
(i) fail to continue the appointment of the Executive as Chairman and Chief
Executive Officer, (ii) reduce the Executive's annual salary below the minimum
amount specified in Appendix A, (iii) materially diminish the duties or
responsibilities of the Executive as Chairman and Chief Executive Officer, as
the same are set forth hereinabove, (iv) assign to the Executive such duties and
responsibilities inconsistent with his position as Chairman and Chief Executive
Officer, or (v) after a change in ownership or control of the Company, relocate
its headquarters to a location more than thirty (30) miles, by air, from its
location immediately prior to such charge in ownership or control (each of the
foregoing hereinafter referred to as a "Triggering Event"), then the Executive
may give notice to the Company of his election to
<PAGE>   27
                                                                              27

terminate this Agreement pursuant to this Section, effective sixty (60) days
from the date of such notice, unless the Company shall have cured the default
giving rise to his Notice of Termination. Such notice from the Executive shall
state the Triggering Event that provides the grounds for his termination, and
such notice must be given, if at all, within one hundred and twenty (120) days
of the occurrence of the Triggering Event referred to as providing such grounds
for termination. Within the sixty (60) day period specified in the Executive's
notice to the Company, the Executive and the Board shall discuss in good faith
what actions the Board might take, and by what date, to cure the default
involved in the Triggering Event specified by the Executive. If within that
sixty (60) day period the Board and the Executive are unable to agree in writing
upon a cure or the date by which such cure shall be provided, the Executive's
termination shall be effective on the date specified in his original notice to
the Company. If within such sixty (60) day period the Board and the Executive
shall agree in writing upon a cure and the date by which it shall be provided,
then on such date the Executive shall notify the Board either (i) that the cure
has been satisfactorily provided, and the Executive is willing to continue his
employment under this Agreement pursuant to the terms hereof (except as such
terms may have been altered by the agreed-upon cure), or (ii) that the cure has
not been satisfactorily provided and the Executive is terminating his employment
hereunder effective immediately.
<PAGE>   28
                                                                              28

         9.       Termination of Employment as a Result of Change in
                  Ownership or Control of the Company

                  (a) In the event that the Company shall enter into an
agreement to merge with, or to sell or otherwise dispose of all or substantially
all of its assets or stock to, or is acquired by another corporation or other
entity (hereinafter, a "Change in ownership or Control"), and the parties to
such agreement do not appoint the Executive as Chairman and Chief Executive
Officer (or to such other position of authority and responsibility as may be
acceptable to the Executive in his sole discretion) of the newly created or
merged entity or purchaser, then the Board shall notify the Executive in
writing, specifying such other senior executive position with the new entity
purchaser, or controlling entity, in which the Executive is to serve, the duties
to be assigned to such position, and any other amendments to the terms and
provisions of this Agreement that the above-mentioned parties propose. In no
event, however, shall the remuneration, benefit coverage, stock option
entitlements or severance payments be less than that provided for in this
Agreement. At any time during the period following such notice and ending six
(6) months from the effective date of the Change in Ownership or Control, the
Executive may elect to give notice to the Company, to the purchaser, to the new
entity, or to the controlling entity as the case may be, that he is terminating
this Agreement pursuant to this Section, effective on the date specified in such
notice. If the Agreement is terminated pursuant to this section the Company
shall provide the Executive
<PAGE>   29
                                                                              29

all benefits and obligations as provided in Section 5 hereof; provided, however,
that prior to the effective date of the Change in Ownership or Control, the
Company shall make arrangements satisfactory to the Executive by providing
adequate security that the new entity, purchaser or controlling entity following
the Change in ownership or Control will have the financial resources to make the
payments and provide for the payments and benefits (or the economic equivalent
thereof) to the Executive on a timely basis in accordance with the terms of this
Agreement.

                  (b) In the event the Change in Ownership or Control results in
the dissolution, elimination or modification of the Company's Incentive Stock
Option Plans or any future stock option plan(s) established by the Company, and
the Executive becomes employed by the successor entity in accordance with
Section 9(a), above, the Executive may, at his sole discretion, elect to (i)
accept participation in and the award of stock options in such stock option
plans of the successor or controlling entity, as offered to him by such
successor or controlling entity, or (ii) receive a payment in cash for such
stock options of the Company as calculated in accordance with the following
formula:

         (A)      All stock options awarded to the Executive by the Company
                  shall be deemed to have become fully vested as of the date on
                  which the Company's Incentive Stock Option Plans or any future
                  stock option plans established by the
<PAGE>   30
                                                                              30

                  Company have been dissolved, eliminated or modified ("the Old
                  Vested Options"). The Executive shall retain the right to
                  exercise all such Options for the full term(s) thereof, and
                  the Company shall take all actions as are necessary to
                  transfer the Options from the Company's qualified stock
                  options plan(s) to the Company's non-qualified stock option
                  plan(s) or such other plans as applicable.

                  The cash equivalent of these Stock Options shall be the
                  average of the then present value of all stock options granted
                  to the Executive over the prior three (3) years, and shall be
                  determined pursuant to the "Black-Scholes" options pricing
                  model.

                  The Executive will be provided with a lump-sum payment, within
                  30 days of the dissolution, elimination or modification of the
                  Company's stock options plans, equal to the calculated cash
                  equivalent of the Old Vested options, plus an additional cash
                  amount (grossed up) to cover all taxes required to be paid by
                  the Executive on this cash equivalent.

         (B)      In addition, the Executive will be credited, for the purpose
                  of this Section, with additional stock options equal to 0.5
                  percent (0.5%) of the fully diluted
<PAGE>   31
                                                                              31

                  capitalization of the Company calculated as of the day before
                  the change in ownership or Control, multiplied by the number
                  of years (including fraction thereof) from that date to the
                  end of the term of this Agreement as set forth in Section 4(a)
                  ("the Cash Equivalency Obligation of Successor"). The cash
                  equivalency of stock options provided in this paragraph shall
                  be determined pursuant to the "Black-Scholes" options pricing
                  model.

                  On the first anniversary date of this Agreement following the
                  Change in ownership or Control, the successor entity shall
                  provide the Executive with a cash payment to be calculated as
                  follows: the Cash Equivalency obligation of Successor
                  multiplied by a fraction the numerator of which is the number
                  of months or fraction thereof from the effective date of the
                  Change in ownership or Control to the anniversary date and the
                  denominator of which is the total number of months or fraction
                  thereof from the effective date of the Change in ownership or
                  Control and the end of the term of this Agreement. On each
                  succeeding anniversary date through the end of the term of
                  this Agreement, the successor entity shall provide the
                  Executive with a cash payment to be calculated as follows: the
                  Cash Equivalency obligation of Successor multiplied by a
                  fraction the numerator of which is 12 and the denominator of
                  which is the total number of months
<PAGE>   32
                                                                              32

                  between the effective date of the Change in ownership or
                  Control and the end of the term of this Agreement.

                  (c) In the event the Change in Ownership or Control results in
the Executive's participation in a medical insurance plan which provides a
lesser amount of benefits or coverage than the Company's medical plan for the
Executive and/or members of his immediate family, the successor or controlling
entity shall provide the Executive with a cash payment sufficient to reimburse
the Executive for all medical expenses incurred by the Executive for himself and
for members of his immediate family, and the successor or controlling entity
shall provide the Executive with an additional cash amount (gross up) to cover
all taxes required to be paid by the Executive on such medical expense
reimbursement.

         10.      Agreement Not to Compete.

         The Executive agrees that during his employment by the Company, and for
a period of one (1) year following the termination of such employment, except if
the Executive's termination arises as a result of a change in ownership or
control as provided for in Section 5(a)(iii) and 9 herein, in which case the
Executive shall not be bound by any post-termination agreement not to compete,
he will not, without the prior written consent of the Company, either directly
or indirectly, on his own behalf or in the service or on behalf of others as a
shareholder (other than ownership of less
<PAGE>   33
                                                                              33

than five percent (5%) of the outstanding voting securities of an entity whose
voting securities are traded on a national securities exchange), officer,
trustee, consultant, or executive or managerial employee, engage in, consult
with or be employed by any competing Business.

         11.      Agreement Not to Solicit Customers.

         The Executive agrees that during his employment by the Company and for
a period of one (1) year following the termination of such employment, except if
the Executive's termination is for cause under Section 7, or voluntary
resignation under Section 4(a)(7), or non-renewal of this Agreement under
Section 6, he will not without the prior written consent of the Company, either
directly or indirectly, on his own behalf or in the service or on behalf of
others, solicit, divert or appropriate, or attempt to solicit, divert or
appropriate, to any Competing Business, any person or entity whose account with
the Company was sold or serviced by or under the supervision of the Executive
during the two (2) years preceding the termination of such employment.

         12.      Agreement Not to Solicit Employees.

         The Executive agrees that during his employment by the Company and for
a period of one (1) year following the termination of such employment, except if
the Executive's termination is for cause
<PAGE>   34
                                                                              34

under Section 7, or voluntary resignation under Section 4(a)(7), or non renewal
or this Agreement under Section 6, he will not, either directly or indirectly,
on his own behalf or in the service or on behalf of others, solicit, divert or
hire away, or attempt to solicit, divert or hire away, to any Competing Business
any person employed by the Company, whether or not such employee is a full-time
employee or a temporary employee of the Company, whether or not such employment
is pursuant to written agreement and whether or not such employment is for a
determined period or is at will.

         13.      Ownership, Non-Disclosure and Non-Use of Confidential
                  Information.

                  (a) The Executive acknowledges and agrees that all
Confidential Information as defined in Section 1(c), hereof, and all physical
embodiments thereof, are confidential to and shall be and remain the sole and
exclusive property of the Company. Upon request by the Company, and in any event
upon termination of his employment with the Company for any reason, the
Executive shall promptly deliver to the Company all property belonging to the
Company, including without limitation, all Confidential Information (and all
embodiments thereof), then in his custody, control or possession.

                  (b) The Executive agrees that he will not, either during the
term of his employment by the Company, or for a period of five (5) years after
the termination of his employment, without the
<PAGE>   35
                                                                              35

prior written consent of the Company, disclose or make available any
Confidential Information, as defined in Section 1(c) hereof, to any person or
entity, nor shall he make or cause to be made, or permit or allow, either on his
own behalf or on behalf of others, any use of such Confidential Information
other than in the proper performance of his duties hereunder.

         14.      Ownership of Inventions.

                  (a) The Executive shall promptly disclose to the Company all
discoveries, inventions, and improvements, patentable or unpatentable, conceived
or made by the Executive, individually or jointly with any other person or
persons, during the period of his employment by the Company (whether or not
during working hours) relating in any manner to the business or activities of
the Company, whether such discovery, invention or improvement be a machine,
apparatus, process, composition, article, or other subject. All such
discoveries, inventions and improvements shall be the sole and exclusive
property of the Company in respect to any and all countries, their territories
and possessions. The Executive shall, during his employment within the Company
and thereafter, perform at the request and expense of the Company all lawful
acts and execute, acknowledge and deliver all such instruments deemed necessary
by the Company to vest in the Company the entire right, title and interest in
and to such discoveries, inventions and improvements, and to enable the Company
to properly
<PAGE>   36
                                                                              36

prepare, file and prosecute applications for and obtain patents (including like
kinds of industrial property) thereon in any and all countries selected by the
Company as well as reissues, renewals and extensions thereof, and to obtain and
record title to such applications and patents so that the Company shall be the
sole and absolute owner thereof in any and all countries in which it may desire
patent or like protection.

                  (b) Any provision in this Agreement requiring the Executive to
assign his rights in any invention does not apply to an invention for which no
equipment, supplies, facility, or trade secret information of the Company was
used and which was developed entirely on the Executive's own time, and: (a)
which does not relate (i) to the Business of the Company or (ii) to the
Company's actual or demonstrably anticipated research or development, or (b)
which does not result from any work performed by the Executive for the Company.

         15.      Business and Travel Expense.

         The Executive shall be reimbursed for his out-of-pocket expenses
incurred in carrying out the Company's business, including all travel and
entertainment expenses reasonably required by the Executive in his position as
Chairman and Chief Executive officer, in accordance with Company policy and upon
proof of such expenditures. It is understood that the Executive's wife may
accompany
<PAGE>   37
                                                                              37

him on business travel when the Executive determines that her presence will
enable him to further the interests of the Company and in such circumstances the
Executive shall be reimbursed for her reasonable out-of-pocket travel and
entertainment expenses as well.

         16.      Financial Planning Expenses.

         The Company shall reimburse the Executive for reasonable costs and
expenses incurred by the Executive for financial, estate and tax planning up to
an aggregate of Ten Thousand Dollars ($10,000) annually.

         17.      Legal and Consulting Fees.

         The Company shall pay all reasonable legal fees and consulting expenses
incurred by the Executive in connection with the negotiation and preparation of
this Agreement.

         18.      Resolution of Disputes

                  (a) Any controversy or claim arising out of or relating to
this Agreement, or the breach thereof, shall be settled by arbitration in the
City of Phoenix, in accordance with the rules of the American Arbitration
Association (the "AAA"). The arbitration shall be before three (3) arbitrators,
all of whom shall be attorneys. One arbitrator shall be appointed by the
Executive; one
<PAGE>   38
                                                                              38

arbitrator shall be appointed by the Company, and the third Arbitrator shall be
selected by the two appointed Arbitrators. In the event the two appointed
Arbitrators are unable to agree upon the third Arbitrator, either party may
petition the Superior Court of the State of Arizona, Maricopa County, for
appointment of the third arbitrator. The arbitrators shall not have the
authority to add to, subtract from or in any way modify the express written
terms of the Agreement, and in rendering an award, the arbitrators shall be
required to adhere to the express written provisions of this Agreement and the
intention of the parties appearing therefrom. The decision of the arbitrators
shall be final and binding on the parties hereto and judgment upon the award
rendered by the arbitrators may be entered in any court having jurisdiction
thereof.

                  (b) The costs for the arbitration shall be borne equally by
both parties.

                  (c) Pending the outcome or resolution of any arbitration, the
Company shall continue payment of all amounts when and as due the Executive
under this Agreement without regard to any dispute; provided, however, that if
the arbitration shall be decided in favor of the Company, the, Executive shall
promptly repay to the Company, with interest at the prime rate as published from
time to time by Chemical Bank, all amounts he would not have been entitled to
receive under this Agreement had the dispute not been taken to arbitration, and
the arbitration award in favor of
<PAGE>   39
                                                                              39

the Company shall be deemed an award in the amount of the repayment
due to the Company.

         19.      Compliance With Securities Laws.

         The Executive shall comply with all federal and state securities laws
and Company policies and guidelines relating thereto concerning insider trading,
reporting requirements, and confidentiality of undisclosed internal material
information about the Company.

         20.      Severability, etc.

                  (a) The Executive agrees that the covenants and agreements
contained in sections 10, 11, 12 and 13 of this Agreement, and the subsections
of those Sections, are of the essence of this Agreement; that each of such
covenants is reasonable and necessary to protect and preserve the interests and
properties of the Company and the Business of the Company; that the company is
engaged in the Business of the company; that irreparable loss and damage will be
suffered by the Company should the Executive breach any of such covenants and
agreements; that each of such covenants and agreements is separate, distinct and
severable not only from the other of such covenants and agreements but also from
the other and remaining provisions of this Agreement; that the unenforceability
of any such covenant or agreement shall not affect
<PAGE>   40
                                                                              40

the validity or enforceability of any other such covenant or agreements or any
other provision or provisions of this Agreement; and that, in addition to other
remedies available to it, the Company shall be entitled to seek both temporary
and permanent injunctive relief to prevent a breach or contemplated breach by
the Executive of any of such covenants or agreements.

                  (b) In the event any provision of this Agreement is held by a
court of competent jurisdiction to be unenforceable because it is invalid or in
conflict with any law of any relevant jurisdiction, the validity of the
remaining provisions shall not be affected, and the rights and obligations of
the parties shall be construed and enforced as if this Agreement did not contain
such invalid or unenforceable provisions.

         21.      No Set-Off By the Company.

         The Company shall continue to provide to the Executive all
compensation, benefits and prerequisites of the office of Chairman and Chief
Executive Officer provided for in this Agreement notwithstanding the existence
of any claim, dispute, action or cause of action by the Company against the
Executive, whether based. upon this Agreement or otherwise. Such dispute, claim
or cause of action by the Company against the Executive shall be resolved in
accordance with Section 18 hereof, with the exception
<PAGE>   41
                                                                              41

of the Company's right to seek injunctive relief provided for in
section 20 hereof.

         22.      Headings.

         The headings of the sections contained in this Agreement are for
convenience only and shall not be deemed to control or affect the meaning or
construction of any provision of this Agreement.

         23.      Notices.

         Any notice to either party hereunder shall be in writing, and shall be
deemed to be sufficiently given to or served on such party, for all purposes, if
the same shall be personally delivered to such party, or sent to such party by
registered mail, postage prepaid, at the address of such party given above.
Either party hereto may change the address to which notices are to be sent to
such party hereunder by written notice of such new address given to the other
party hereto.

         24.      Governing Law.

         This Agreement shall be governed by and construed and enforced in
accordance with the laws of the State of Arizona applicable to contracts to be
performed therein, without regard to conflict of laws principles.
<PAGE>   42
                                                                              42

         25.      Assignment.

         This Agreement may not be assigned by the Company without the prior
written consent of the Executive. The Executive shall have the right to
designate a beneficiary, his executor, his administrator or his estate to
receive any payments or benefits payable under this Agreement upon his death.

         26.      Waiver.

         Except as otherwise provided for in this Agreement, no term or
condition of this Agreement shall be deemed to have been waived, nor shall there
be any estoppel against the enforcement of any provision of this Agreement,
except by written instrument of the party charged with such waiver or estoppel.
No such written waiver shall be deemed a continuing waiver unless specifically
stated therein, and each such waiver shall operate only as to the specific term
or condition waived and shall not constitute a waiver of such term or condition
for the future or as to any act other than that specifically waived.

         27.      Amendment of Agreement.

         This Agreement may not be modified or amended except by an instrument
in writing signed by the parties hereto.
<PAGE>   43
                                                                              43

         28.      Entire Agreement.

         This Agreement represents the entire understanding of the parties
hereto and supersedes any prior understandings or agreements between the
parties, except that this Agreement shall not affect or operate to reduce any
benefit or compensation inuring to the Executive of a kind elsewhere provided
and not expressly provided in this Agreement.

         IN WITNESS WHEREOF, the Executive has executed this Agreement and the
Company has caused this Agreement to be executed by its representative thereunto
duly authorized as of the date set forth above.

                                           MEDICIS PHARMACEUTICAL CORPORATION

                                  By: /s/ Michael A. Pietrangelo
                                      -----------------------------------------
                                      Michael A. Pietrangelo
                                      Chairman of the Executive Committee
                                       of the Board of Directors

                                  By: /s/ Joseph Salvani
                                     ------------------------------------------
                                     Joseph Salvani
                                     Chairman, Compensation Committee,
                                      Member of Board of Directors

                                  By: /s/ Jonah Shacknai
                                     ------------------------------------------
                                     Jonah Shacknai
<PAGE>   44
 EXHIBIT A - STOCK OPTION AND COMPENSATION COMMITTEE

The following sets forth the Executive's compensation in accordance with
paragraph 3(a):

1.       Annual base compensation*          $400,000 per year
         ("Base Salary")

2.       Health/Medical and other           Actual cost
         employee benefits pro-
         vided to other employees
         of the Company.

3.       Health Club Membership             $100 per month

4.       Automobile Allowance               $900 per month

5.       Incentive Stock Options            Minimum annual award of .5 percent 
                                            (.5%) of the fully diluted         
                                            capitalization of the Company to be
                                            awarded no earlier than thirty (30)
                                            days before or no later than thirty
                                            (30) days after the anniversary    
                                            date of this Agreement. In the     
                                            event of a change in ownership or  
                                            control of the Company, or if the  
                                            Company's Incentive Stock Option   
                                            Plans are dissolved, eliminated or 
                                            modified, then the Executive shall 
                                            receive in lieu of this minimum    
                                            annual award, a minimum annual     
                                            award equal to the "cash           
                                            equivalent" as set forth and       
                                            provided for in Section 9(b).      
                                            
6.       Annual Cash Bonus                  The Board agrees to determine, in  
                                            good faith, the annual cash bonus  
                                            to be provided to the Executive    
                                            based upon the Executive's         
                                            performance and the performance of 
                                            the Company measured against the   
                                            Company's fiscal plan for the prior
                                            fiscal year.                       

*The Stock Option and Compensation Committee will review the base salary amount
annually and provide an increase in the Executive's base annual compensation as
appropriate and within its discretion.

<PAGE>   1
                                                                EXHIBIT 10.72(b)
                FIRST AMENDMENT TO CREDIT AND SECURITY AGREEMENT

         THIS FIRST AMENDMENT TO CREDIT AND SECURITY AGREEMENT (the "Amendment")
is made as of the 29th day of May, 1996 by and between MEDICIS PHARMACEUTICAL
CORPORATION, a Delaware corporation ("Borrower"), and NORWEST BANK ARIZONA,
NATIONAL ASSOCIATION, a national banking association, as successor-in-interest
to NORWEST BUSINESS CREDIT, INC., a Minnesota corporation ("Lender").

                                R E C I T A L S:

         WHEREAS, Borrower and Norwest Business Credit, Inc. ("NBCI") are
parties to that certain Credit and Security Agreement dated as of August 3,
1995, as modified by letter agreements dated March 6, 1996 and April 11, 1996
(collectively, the "Credit Agreement"), pursuant to which NBCI agreed to make
available to Borrower, on a revolving basis, a sum not to exceed $2,000,000 (the
"Revolving Loan"), which Revolving Loan is evidenced by that certain Promissory
Note dated August 3, 1995 from Borrower to NBCI in an amount not to exceed
$2,000,000 (the "Revolving Note");

         WHEREAS, NBCI has assigned, and Lender has assumed, all of NBCI's
right, title, interest, privileges, obligations and liabilities under the Credit
Agreement, as amended, and any documents, agreements or instruments evidencing,
securing or in any way related to Borrower's obligations under the Credit
Agreement, as amended (the "Loan Documents"), subject to and on the terms and
conditions contained herein; and

         WHEREAS, Borrower has requested that Lender commit to advance an
additional $3,000,000 to finance capital expenditures, product development
costs, brand purchase contracts, licensing agreements and other financial needs
mutually agreed upon in writing by Borrower and Lender in their sole and
absolute discretion, and Lender has agreed thereto on the terms and conditions
set forth herein;

         NOW, THEREFORE, in consideration of the premises and the mutual
covenants contained herein and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged, Borrower and Lender,
intending to be legally bound, agree as follows:

         1. INTERPRETATION. Except as otherwise defined herein, all capitalized
terms used herein shall have the meanings ascribed thereto in the Credit
Agreement.

         2. RECITALS. The recitals set forth above are true and accurate in
every respect.

         3. OUTSTANDING INDEBTEDNESS. As of May 29, 1996: the outstanding
principal balance of the Revolving Loan is $0.00; the accrued and unpaid
interest on the Revolving Loan is $0.00; the prorated Minimum Interest Charge
(including the unused 

                                       -1-
<PAGE>   2
fee described in Section 2.11(b) of the Credit Agreement) payable to NBCI is
$24,843.36; and the collateral examination fee previously incurred by, and
payable to, NBCI is $2,300.

         4. NO OFFSETS. Borrower acknowledges with respect to the amounts owing
to Lender that, as of the date of execution of this Amendment, Borrower has no
offset, defense or counterclaim with respect thereto, no claim or defense in the
abatement or reduction thereof, or any other claim against Lender or NBCI or
with respect to any document forming part of the transaction in respect of which
the Revolving Loan was made or forming part of any other transaction under which
Borrower is indebted to Lender or NBCI. Borrower acknowledges that all interest
imposed under the Revolving Note through the date of execution hereof, and all
fees and other charges that have been collected from or known by Borrower to
have been imposed upon Borrower with respect to the Revolving Loan evidenced by
the Revolving Note were and are agreed to, and were properly computed and
collected, and that NBCI has fully performed all obligations that it may have
had or now has to Borrower, and neither NBCI nor Lender has any obligation to
make any additional loan or extension of credit to or for the benefit of
Borrower, except as provided in the Credit Agreement, as amended by this
Amendment.

         5. REPRESENTATIONS AND WARRANTIES OF BORROWER. To induce Lender to
enter into this Amendment and the arrangement contemplated by this Amendment,
Borrower represents and warrants to Lender as follows:

                  (a) This Amendment and all other instruments executed and
delivered to Lender concurrently herewith, were executed in accordance with the
requirements of law and in accordance with any requirements of Borrower's
certificate of incorporation and bylaws and any amendments thereto.

                  (b) The execution and delivery of this Amendment and any other
instruments executed and delivered to Lender concurrently herewith, and the full
and complete performance of the provisions hereof will not result in any breach
of, or constitute a default under, or result in the creation of any lien, charge
or encumbrance upon any property or assets of Borrower under any indenture,
mortgage, deed of trust, bank loan or credit agreement or other instrument to
which Borrower is a party or by which Borrower is bound.

                  (c) The Loan Documents executed by Borrower and this Amendment
are the legal, valid and binding obligations of Borrower enforceable against
Borrower in accordance with their terms.

                  (d) There is no pending or overtly threatened litigation
involving Borrower.

                                       -2-
<PAGE>   3
                  (e) Borrower has not derived ten percent (10%) or more of
Borrower's Net Sales in any Fiscal Year from any Applicable License as described
in Section 6.14 of the Credit Agreement.

                  (f) The patent applications described in Exhibit F to this
First Amendment are the only patent applications Borrower has pending before the
PTO Office and none of the pending patent applications has yet been approved by
the PTO Office.

                  (g) The Beecham Loan (as defined in the Credit Agreement) has
been paid in full and any collateral securing the Beecham Loan has been duly
released of record.

                  (h) There are no oral agreements, understandings or course of
conduct that would modify, amend, rearrange, vary, diminish or impair the Loan
Documents or the obligation of Borrower to pay the indebtedness evidenced
thereby or to perform fully the obligations of Borrower in strict accordance
with the Loan Documents, or which would permit Borrower to void or avoid its
obligations in whole or in part.

                  (i) The indebtedness relating to the financing statement from
Borrower, as debtor, to Victor T. Weber, as Collateral Agent, as secured party,
filed on August 10, 1993 in File No. 32228383, Financing Records of the Maryland
State Department of Assessments and Taxation, has been paid in full and the
secured party has no further obligation to advance monies to Borrower.

                  (j) All of the respective representations and warranties made
by Borrower in the Loan Documents remain true, complete and correct as of the
date hereof, including, without limitation, the representations and warranties
in Section 5 of the Credit Agreement.

No representation or warranty made by Borrower and contained herein or in the
other Loan Documents, and no certificate, information or report furnished or to
be furnished by Borrower in connection with any of the Loan Documents or any of
the transactions contemplated hereby or thereby, contains or will contain a
misstatement of material fact, or omits or will omit to state a material fact
required to be stated in order to make the statements contained herein or
therein not misleading in the light of the circumstances under which such
statements were made.

         6. CONTINUED ENFORCEABILITY OF LOAN DOCUMENTS. Except as modified
herein, all of the terms and provisions of the Loan Documents remain in full
force and effect. In the event of any conflict between the terms and provisions
of this Amendment and the terms and provisions of the Loan Documents, the terms
and provisions of this Amendment shall govern and prevail. Borrower
acknowledges, confirms and ratifies the enforceability of the Credit Agreement,
the Revolving Note and the Loan Documents, as modified pursuant to this
Amendment, and the continuing validity,

                                       -3-
<PAGE>   4
enforceability and priority of the liens and security interests granted in the
Loan Documents.

         7.       RELEASE OF CLAIMS.

                  (a) Borrower hereby releases Lender and NBCI, their officers,
employees and agents from all claims and demands (known and unknown) it may have
on the date hereof arising out of or in any way relating to the extension or
denial of credit by NBCI or the Lender to Borrower or other matters relating to
the indebtedness, any collateral securing payment and performance of such
indebtedness, or any matter preliminary to the execution and delivery by
Borrower and Lender of this Amendment. The release set forth above shall not
extend to any claim arising after the date hereof to the extent based on acts or
omissions of Lender occurring after such date, except that such release is
specifically intended by the parties to include the transactions leading up to
the execution of this Amendment. This Amendment and the release provisions
contained in this Section 7 are contractual, and not a mere recital.

                  (b) Borrower acknowledges and agrees that Lender is not, and
shall not be, obligated in any way to continue or undertake any loan, financing
or other credit arrangement with Borrower, including, without limitation, any
renewal of the indebtedness evidenced by the Loan Documents, except on the terms
and subject to the conditions set forth in the Loan Documents as hereby amended
and modified.

         8. CONDITIONS OF CLOSING. Lender's obligation to enter into this
Amendment and the other documents and instruments required hereunder shall be
subject to the satisfaction of all of the following conditions on or before May
29, 1996 (the "Closing" or the "Closing Date") in a manner, form and substance
satisfactory to Lender, which conditions may be waived by Lender in its sole and
absolute discretion:

                  (a) On the Closing Date the representations and warranties of
Borrower set forth in the Loan Documents shall be true and correct in all
material respects when made and at and as of the time of the Closing.

                  (b) The following shall have been delivered to Lender, each
duly authorized, executed and acknowledged, where applicable:

                           (i) An Assignment of the Loan Documents from NBCI to
                  Lender.

                           (ii) Assignments by NBCI to Lender of each of the
                  UCC-1 Financing Statement from Borrower to NBCI.

                           (iii) This Amendment.

                                       -4-
<PAGE>   5
                           (iv) A Multiple Advance Note from Borrower payable to
                  Lender in the original principal amount not to exceed
                  $3,000,000.

                           (v) A UCC-1 Financing Statement from Borrower in
                  favor of Lender to be filed in the central filing agency of
                  the State of Maryland.

                           (vi) An Amendment to the Collateral Account
                  Agreement.

                           (vii) An Amendment to the Patent Collateral
                  Assignment and Security Agreement.

                           (viii) An Amendment to the Trademark, Tradename and
                  Service Mark Collateral Assignment and Security Agreement.

                           (ix) An Amendment to the Agreement as to Lockbox
                  Services.

                           (x) A Consent from CEDC in connection with the
                  Intercreditor Agreement between CEDC and NBCI.

                           (xi) A Consent from Londen Center L.L.C. in
                  connection with the Landlord's Subordination, Disclaimer and
                  Consent dated as of August 3, 1995 among NBCI, Borrower and
                  Londen Center L.L.C.

                           (xii) A Consent from USCO Distribution Services, Inc.
                  ("USCO") in connection with the Tri-Party Agreement among
                  NBCI, Borrower and USCO.

                  (c) Borrower shall have performed and complied in all material
respects with all agreements and conditions contained in the Loan Documents to
be performed by or complied with by Borrower prior to or at the Closing, and no
Event of Default or Default shall have occurred and be continuing or would occur
by Borrower entering into this Amendment and each condition precedent to the
effectiveness of each of the Loan Documents shall have been satisfied.

                  (d) Lender shall have received such documents as Lender shall
require to establish the proper organization and good standing of Borrower, the
authority of Borrower to execute this Amendment and any other documents or
instruments required hereunder, and evidence that all approvals and/or consents
of, or other action by, any shareholder, governmental agency or other Person
whose approval or consent is necessary or required to enable Borrower to (a)
enter into and perform its obligations under the Loan Documents and (b) grant to
Lender the Security Interests, have been obtained.

                  (e) All filings of Uniform Commercial Code financing
statements and other filings and actions necessary to perfect and maintain the
Security Interests as

                                       -5-
<PAGE>   6
first, valid and perfected security interest in the Collateral shall have been
filed or taken (or such filings delivered for filing immediately following the
Closing, to Lender or a third party acceptable to Lender) and confirmation
thereof shall have been received by Lender.

                  (f) Lender shall have determined to its satisfaction that, as
of the Closing Date, there has been no material adverse change in the financial
condition of Borrower from the financial statements dated as of March 31, 1996
and other documents submitted by Borrower to Lender prior to the Closing Date.

                  (g) Borrower shall have paid to Lender an origination fee of
$50,000, which shall be fully earned and non-refundable upon Lender's execution
and delivery of this Amendment (Lender shall pay its attorneys' fees associated
with negotiating and preparing this Amendment and the related documents).

                  (h) Lender shall be satisfied that (a) Borrower has good and
indefeasible title to all of the Collateral and (b) Borrower at all times shall
be entitled to the use and quiet enjoyment of all assets necessary and desirable
for the continued ownership and operation of Borrower's business, including,
without limitation, the use of equipment, licenses, fixtures and warehouses.

                  (i) Borrower shall have paid all of Lender's out-of-pocket
costs and expenses incurred in connection with UCC lien, litigation and judgment
searches and verifications and filing and recording fees.

                  (j) Borrower shall have paid all of the fees and reimbursable
costs and expenses due to NBCI pursuant to Section 3 hereof.

         9. DEFINITIONS. (a) The definitions of "Beecham Loan" and "Minimum
Interest Charge" in Section 1.1 of the Credit Agreement is hereby deleted in its
entirety; (b) the definitions of "Base Rate", "Floating Rate", "Loan Documents"
and "Termination Date" in Section 1.1 of the Credit Agreement are hereby deleted
in their entirety and the following inserted therefor:

                           "Base Rate" means the rate of interest publicly
                  announced from time to time by Norwest Bank Arizona, National
                  Association, as its "base rate" or, if such bank ceases to
                  announce a rate so designated, any similar successor rate
                  designated by the Lender.

                           "Floating Rate" means an annual rate equal to the sum
                  of the Base Rate plus 125 basis points, which Floating Rate
                  shall change when and as the Base Rate changes.

                                       -6-
<PAGE>   7
                           "Loan Documents" means this Agreement, the Notes, the
                  Financing Statements Form UCC-1, the Security Documents and
                  all other documents previously, concurrently or hereafter
                  executed or delivered in connection with the Revolving Credit
                  Facility or the Term Credit Facility.

                           "Termination Date" means July 31, 1997.

and (c) Section 1.1 of the Credit Agreement is hereby amended to add the
following definitions in proper alphabetical order:

                           "Borrowing Base Certificate" means a monthly
                  statement, in form approved by Lender, showing Accounts,
                  Eligible Accounts, Inventory and Eligible Inventory by
                  location, and the outstanding principal balance on the
                  Revolving Credit Facility at the last day of each month,
                  certified as correct by Borrower's President or Chief
                  Financial Officer.

                           "Current Assets" means cash, cash equivalents,
                  including Permitted Investments, trade receivables, tax
                  refunds and inventory.

                           "Current Ratio" means, as of any date of
                  determination, on a consolidated basis, the ratio of Current
                  Assets to current liabilities under GAAP.

                           "Maturity Date" means July 31, 2001.

                           "Maximum Amount" means $3,000,000.

                           "Net Worth" means the gross value of the Borrower's
                  Equity plus debt subordinated to the Lender in a manner
                  acceptable to the Lender (using the Lender's standard form).
                  "Equity" means Borrower's retained earnings plus the "book
                  value" of all issued and outstanding stock in Borrower
                  (including all common and preferred), plus paid-in capital
                  less treasury stock.

                           "Permitted Investments" means investments in direct
                  obligations of the United States of America or any agency or
                  instrumentality thereof whose obligations constitute full
                  faith and credit obligations of the United States of America
                  having a maturity of one year or less, commercial paper issued
                  by U.S. corporations rated "A-1" or "A-2" by Standard 

                                       -7-
<PAGE>   8
                  & Poor's Corporation or "P-1" or "P-2" by Moody's Investors
                  Service or certificates of deposit or bankers' acceptances
                  having a maturity of one year or less issued by members of the
                  Federal Reserve System having deposits in excess of
                  $100,000,000 (which certificates of deposit or bankers'
                  acceptances are fully insured by the Federal Deposit Insurance
                  Corporation and "Money Market Funds" acquired through an FDIC
                  insured bank and/or a division or subsidiary thereof.

                           "Revolving Credit Facility" means the working capital
                  credit facility not to exceed the Commitment being made
                  available to Borrower by Lender pursuant to Article 2 hereof.

                           "Tangible Net Worth" means, as of any date of
                  determination, on a consolidated basis, Net Worth less the net
                  book value (after deducting reserves applicable thereto) of
                  all assets classified as intangible assets under GAAP,
                  including, without limitation, goodwill, trademarks, trade
                  names, service marks, copyrights, patents, licenses, permits,
                  covenants not to compete, and rights related thereto, less any
                  stock or other securities or evidences of indebtedness of any
                  other Person, any loans or advances to any other Person, or
                  any investment or interest whatsoever in any other Person,
                  including specifically, but without limitation, any
                  partnership or joint venture, except Permitted Investments.

                           "Term Credit Facility" means term credit facility not
                  to exceed the Maximum Amount being made available to Borrower
                  by Lender pursuant to Article 2 hereof.

                           "Term Note" means the multiple advance promissory
                  note from Borrower payable to Lender in the principal amount
                  not to exceed the Maximum Amount and any amendments,
                  modifications, supplements, consolidations, replacements or
                  consolidations thereto or thereof, including, without
                  limitation, any replacement note issued pursuant to Section
                  2.13 hereof.

                           "Treasury Bill Constant" means the sum of (x)(i) the
                  yield to maturity reported, as of 10:00 a.m. (New York City
                  time) on the third Business Day preceding the Termination
                  Date, on the display designated as "Page 678" on the 

                                       -8-
<PAGE>   9
                  Telerate Service (or such other display as may replace Page
                  678 on the Telerate Service) for actively traded U.S. Treasury
                  securities having a maturity of forty-eight (48) months from
                  the Termination Date (as near as practicable) or (ii) if such
                  yields shall not be reported as of such time or the yields
                  reported as of such time shall not be ascertainable, the
                  Treasury Constant Maturity Series yields reported, for the
                  latest day for which such yields shall have been so reported
                  on or prior to the third Business Day preceding the
                  Termination Date, in Federal Reserve Statistical Release H.15
                  (519) (or any comparable successor publication) for actively
                  traded U.S. Treasury securities having a constant maturity of
                  forty-eight (48) months from the Termination Date (as near as
                  practicable) plus (y) three hundred (300) basis points.

         10. ADVANCES. (a) The preface to Section 2.1 of the Credit Agreement is
hereby deleted in its entirety and the following inserted therefor:

                           Section 2.1 Advances. The Lender agrees, on the terms
                  and subject to the conditions herein set forth, to make
                  Advances to the Borrower from time to time during the period
                  from the date hereof to and including the Termination Date, or
                  the earlier date of termination in whole of the Revolving
                  Credit Facility and Term Credit Facility pursuant to Sections
                  2.4(a) or 8.2 hereof, in an aggregate amount at any time
                  outstanding not to exceed the Borrowing Base, with respect to
                  the Revolving Credit Facility, and the Maximum Amount, with
                  respect to the Term Credit Facility, which Advances shall be
                  secured by the Collateral as provided in Article 3 hereof. The
                  Revolving Credit Facility shall be a revolving facility and it
                  is contemplated that the Borrower will request Advances, make
                  prepayments and request additional Advances thereunder and the
                  Term Credit Facility shall be a term facility and it is
                  contemplated that Borrower will request Advances for capital
                  expenditures, product development costs, brand purchase
                  contracts, licensing agreements and other purposes mutually
                  agreed upon in writing by Borrower and Lender in their sole
                  and absolute discretion, which Advances will be repaid in
                  accordance with the terms of this Agreement. The Borrower
                  agrees to comply with the following procedures in requesting
                  Advances under this Section 2.1:

                                       -9-
<PAGE>   10
and (b) Section 2.1(b) of the Credit Agreement is hereby deleted in its entirety
and the following inserted therefor:

                           (b) Each request for an Advance under this Section
                  2.1 shall be made to the Lender prior to 11:00 a.m. (Phoenix
                  time) of the day of the requested Advance by the Borrower.
                  Each request for an advance may be made in writing or by
                  telephone, specifying the date of the requested Advance and
                  the amount thereof, and (i) shall specify whether it is an
                  Advance under the Revolving Credit Facility or the Term Credit
                  Facility and the purpose of the Advance, and (ii) shall be
                  made by (A) any officer of the Borrower; or (B) any person
                  designated as the Borrower's agent by any officer of the
                  Borrower in a writing delivered to the Lender; or (C) any
                  person reasonably believed by the Lender to be an officer of
                  the Borrower or such a designated agent.

         11. NOTE. Section 2.2 of the Credit Agreement is hereby deleted in its
entirety and the following inserted therefor:

                           Section 2.2 Notes. All Advances made by the Lender
                  under this Section 2.1 shall be evidenced by and repayable
                  with interest in accordance with the Note and the Term Note.
                  The principal of the Note shall be payable as provided herein
                  and on the earlier of the Termination Date or acceleration by
                  the Lender pursuant to Section 8.2 hereof, and shall bear
                  interest as provided herein. The principal of the Term Note
                  shall be payable as provided herein and shall bear interest as
                  provided herein, and, absent acceleration by the Lender
                  pursuant to Section 8.2 hereof, shall be amortized commencing
                  on the Termination Date as provided herein.

         12. INTEREST. Section 2.3(b) of the Credit Agreement is hereby deleted
in its entirety and the following inserted therefor:

                           (b)      INTENTIONALLY DELETED

         13. VOLUNTARY PREPAYMENT; TERMINATION OF AGREEMENT BY THE BORROWER;
PERMANENT REDUCTION OF COMMITMENT. (a) Section 2.4(a) of the Credit Agreement is
hereby deleted in its entirety and the following inserted therefor:

                           (a) Borrower may, in its discretion, prepay the
                  Advances in whole at any time or from time to time in part.
                  The Borrower may terminate this Agreement at any time 

                                      -10-
<PAGE>   11
                  and, subject to payment and performance of all the Borrower's
                  obligations to the Lender, the Lender shall promptly release
                  the Security Interest and the Borrower may obtain any release
                  or termination of the Security Interest to which the Borrower
                  is otherwise entitled by law by giving at least 30 days' prior
                  written notice to the Lender of the Borrower's intention to
                  terminate this Agreement.

and (b) Section 2.4(b) of the Credit Agreement is hereby deleted in its entirety
and the following inserted therefor:

                           (b)      INTENTIONALLY DELETED

         14. MANDATORY PREPAYMENT. Section 2.5 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                           Section 2.5 Mandatory Prepayment. Without notice or
                  demand, if the sum of the outstanding principal balance of the
                  Advances with respect to the Note shall at any time exceed the
                  Borrowing Base, the Borrower shall within forty-eight (48)
                  hours (excluding Saturdays, Sundays and Holidays) thereof
                  prepay the Advances to the extent necessary to reduce the sum
                  of the outstanding principal balance of the Advances with
                  respect to the Note to the Borrowing Base. Any payment
                  received by the Lender under this Section 2.5 or under Section
                  2.4 may be applied to the Advances under the Revolving Credit
                  Facility, including interest thereon and any fees,
                  commissions, costs and expenses due and unpaid hereunder and
                  under the Security Documents, in such order and in such
                  amounts as the Lender, in its discretion, may from time to
                  time determine, and, if a Default or Event of Default has
                  occurred and is continuing, to the Advances under the Term
                  Credit Facility, including interest thereon.

         15. USE OF PROCEEDS. Section 2.8 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                           Section 2.8 Use of Proceeds. The proceeds of Advances
                  with respect to the Revolving Credit Facility shall be used by
                  the Borrower for ordinary working capital purposes and the
                  proceeds of Advances with respect to the Term Credit Facility
                  shall be used by the Borrower for capital expenditures,
                  product development costs, brand purchase contracts, licensing
                  agreements and other purposes 

                                      -11-
<PAGE>   12
                  mutually agreed upon in writing by Borrower and Lender in
                  their sole and absolute discretion.

         16. FEES. (a) Section 2.11(a) of the Credit Agreement is hereby deleted
in its entirety and the following inserted therefor:

                           (a) The Borrower hereby agrees to pay Lender a fully
                  earned and non-refundable origination fee of $50,000 upon the
                  execution of the First Amendment to Credit and Security
                  Agreement dated as of May 29, 1996 between Borrower and Lender
                  (the "First Amendment").

(b) Section 2.11(b) of the Credit Agreement is hereby deleted in its entirety
and the following inserted therefor:

                           (b)      INTENTIONALLY DELETED

and (c) Section 2.11(c) of the Credit Agreement is hereby deleted in its
entirety and the following inserted therefor:

                           (c) Provided that no Default or Event of Default has
                  occurred and is continuing, Lender shall not undertake more
                  than two (2) collateral audits or inspections of the
                  operations or business of the Borrower in any Fiscal Year and
                  Borrower shall not be required to pay any audit fees or
                  out-of-pocket costs and expenses incurred by Lender in
                  connection with any such audits or inspections by the Lender
                  of any collateral or the corresponding operations or business
                  of the Borrower after May 29, 1996. Upon the occurrence of a
                  Default or Event of Default and during the continuance
                  thereof, Lender may undertake such collateral audits and
                  inspections of the operations or business of the Borrower as
                  Lender deems necessary in its sole and absolute discretion and
                  the Borrower hereby agrees to pay the Lender, on demand, audit
                  fees of $50 per hour (or the then applicable rate charged by
                  Lender) per auditor in connection with any such audits or
                  inspections by the Lender of any collateral or the
                  corresponding operations or business of the Borrower, together
                  with all actual out-of-pocket costs and expenses incurred in
                  conducting any such audit or inspection.

         17. AMORTIZATION OF TERM CREDIT FACILITY. Article 2 of the Credit
Agreement is hereby amended to add the following:

                                      -12-
<PAGE>   13
                           Section 2.13 Amortization of Term Credit Facility.
                  Provided that no Default or Event of Default has occurred and
                  is continuing, on the Termination Date, all of the accrued and
                  unpaid interest and other fees and charges shall be due and
                  payable and, at Borrower's election to be made in writing on
                  or prior to the Termination Date, (a) the then outstanding
                  principal balance of the Term Credit Facility shall be
                  amortized over a forty-eight month period and paid in equal
                  principal payments, plus interest at the Floating Rate, on the
                  last day of each month, commencing August 31, 1997 and
                  continuing on the last day of each month thereafter until the
                  Maturity Date, at which time the entire outstanding principal
                  balance of the Term Credit Facility, all accrued and unpaid
                  interest and all other fees and charges shall be due and
                  payable, or (b) the then outstanding principal balance of the
                  Term Credit Facility shall be amortized over a forty-eight
                  month period, with interest calculated at the Treasury Bill
                  Constant, and paid in level principal and interest payments on
                  the last day of each month, commencing August 31, 1997 and
                  continuing on the last day of each month thereafter until the
                  Maturity Date, at which time the entire outstanding principal
                  balance of the Term Credit Facility, all accrued and unpaid
                  interest and all other fees and charges shall be due and
                  payable. At the request of Lender, Borrower shall execute and
                  deliver a replacement promissory note for the Term Note. In
                  the event that Borrower fails to make an election on or prior
                  to the Termination Date, Borrower shall be deemed to have
                  elected clause (a) above.

         18. CONDITIONS PRECEDENT TO THE INITIAL ADVANCE. Section 4.1 of the
Credit Agreement is hereby amended to add the following:

                                    (u) A certificate of the Secretary or an
                  Assistant Secretary of the Borrower, certifying as to the
                  resolutions of the directors and, if required, the
                  shareholders of the Borrower, authorizing the execution,
                  delivery and performance of the First Amendment, the Term Note
                  and the other documents and all documents and instruments
                  incident thereto and to the transactions contemplated thereby,
                  satisfactory to Lender and its counsel.

                                    (v) An opinion of counsel to the Borrower,
                  addressed to Lender, with respect to the transactions

                                      -13-
<PAGE>   14
                  contemplated by the First Amendment, in form and substance
                  satisfactory to Lender and its counsel.

         19. FINANCIAL CONDITION; NO ADVERSE CHANGE. Section 5.5 of the Credit
Agreement is hereby deleted in its entirety and the following inserted therefor:

                           Section 5.5 Financial Condition; No Adverse Change.
                  The Borrower has heretofore furnished to the Lender audited
                  financial statements of the Borrower for its Fiscal Year ended
                  June 30, 1995 and unaudited financial statements of the
                  Borrower for the months ended through March 31, 1996, and
                  those statements fairly present the financial condition of the
                  Borrower on the dates thereof and the results of its
                  operations and cash flows for the periods then ended and were
                  prepared in accordance with generally accepted accounting
                  principles. Since the date of the most recent financial
                  statements of the Borrower, there has been no material adverse
                  change in the business, properties or condition (financial or
                  otherwise) of the Borrower.

         20. REPORTING REQUIREMENTS. (a) Section 6.1(l) of the Credit Agreement
is hereby deleted in its entirety and the following inserted therefor:

                           (c) within 15 days after the end of each month,
                  agings of the Borrower's accounts receivable and its accounts
                  payable and a Borrowing Base Certificate as at the end of such
                  month;

Section 6.1(l) of the Credit Agreement is hereby deleted in its entirety and the
following inserted therefor:

                           (l) promptly after the sending or filing thereof,
                  copies of all regular and periodic financial reports and
                  special reports which the Borrower shall file with the
                  Securities and Exchange Commission or any national securities
                  exchange, including, without limitation, reports on Form 10-Q,
                  Form 10-K and Form 8-K.

         21. INCOME TAX RETURNS. Section 6.1 of the Credit Agreement is hereby
amended to add the following:

                           (o) as soon as available and in any event within
                  thirty (30) days following the filing of Borrower's federal
                  income tax return, a copy of such federal income tax return
                  and, if such federal income tax return is not filed on or

                                      -14-
<PAGE>   15
                  before October 15, then on or before November 15, a copy of
                  the completed request for extension delivered to the Internal
                  Revenue Service followed by the federal income tax return when
                  filed.

         22. LOCKBOX; COLLATERAL ACCOUNT. Section 6.10 of the Credit Agreement
is hereby deleted in its entirety and the following inserted therefor:

                           Section 6.10  Lockbox; Collateral Account.

                           (a) The Borrower will irrevocably direct all present
                  and future Account debtors and other Persons obligated to make
                  payments constituting Collateral to make such payments
                  directly to the Lockbox. All of the Borrower's invoices,
                  account statements and other written or oral communications
                  directing, instructing, demanding or requesting payment of any
                  Account or any other amount constituting Collateral shall
                  conspicuously direct that all payments be made to the Lockbox
                  and shall include the Lockbox address. Upon confirmation of
                  good, collected funds, all payments made to the Lockbox shall
                  be processed to Borrower's operating account no. 6438801379
                  maintained with Lender. In Lender's sole and absolute
                  discretion, all payments received in the Lockbox may be
                  processed to the Collateral Account.

                           (b) Upon the written request of Lender, the Borrower
                  agrees to deposit in the Collateral Account or, at the
                  Lender's option, to deliver to the Lender all collections on
                  Accounts, contract rights, chattel paper and other rights to
                  payment constituting Collateral, and all other cash proceeds
                  of Collateral, which the Borrower may receive directly
                  notwithstanding its direction to Account debtors and other
                  obligors to make payments to the Lockbox, immediately upon
                  receipt thereof, in the form received, except for the
                  Borrower's endorsement when deemed necessary. Until delivered
                  to the Lender or deposited in the Collateral Account, all
                  proceeds or collections of Collateral shall be held in trust
                  by the Borrower for and as the property of the Lender and
                  shall not be commingled with any funds or property of the
                  Borrower. Amounts deposited in the Collateral Account shall
                  not bear interest and shall not be subject to withdrawal by
                  the Borrower, except after full payment and discharge of all
                  Obligations. All such collections shall constitute proceeds of
                  Collateral and shall 

                                      -15-
<PAGE>   16
                  not constitute payment of any Obligation. Collected funds from
                  the Collateral Account shall be transferred to the Lender's
                  general account, and the Lender may deposit in its general
                  account or in the Collateral Account any and all collections
                  received by it directly from the Borrower. The Lender may
                  commingle such funds with other property of the Lender or any
                  other person. The Lender from time to time at its discretion
                  shall, after allowing two (2) Banking Days after deposit in
                  the Collateral Account, apply such funds to the payment of any
                  or all Obligations, in any order or manner of application
                  satisfactory to the Lender. All items delivered to the Lender
                  or deposited in the Collateral Account shall be subject to
                  final payment. If any such item is returned uncollected, the
                  Borrower will immediately pay the Lender, the amount of that
                  item, or Lender at its discretion may charge any uncollected
                  item to the Borrower's operating account or other account. The
                  Borrower shall be liable as an endorser on all items deposited
                  in the Collateral Account, whether or not in fact endorsed by
                  the Borrower.

         23. MINIMUM NET INCOME. Section 6.12 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                           Section 6.12 Tangible Net Worth. Borrower shall
                  maintain on a consolidated basis Tangible Net Worth in the
                  following amounts as of the following dates:
<TABLE>
<CAPTION>
          ===========================================================
           FISCAL QUARTER END                    TANGIBLE NET WORTH
          -----------------------------------------------------------
          <S>                                        <C>
            June 30, 1996                               $5,700,000
          -----------------------------------------------------------
            September 30, 1996                          $7,000,000
          -----------------------------------------------------------
            December 31, 1996                           $8,800,000
          -----------------------------------------------------------
            March 31, 1997                             $10,500,000
          -----------------------------------------------------------
            June 30, 1997 and thereafter               $12,500,000
            during the term of this
            Agreement
          ===========================================================
</TABLE>

         24. NET WORTH INCREASE. Section 6.13 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                                      -16-
<PAGE>   17
                           Section 6.13     INTENTIONALLY DELETED

         25. BEECHAM LOAN. Section 6.16 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                           Section 6.16 Total Liabilities to Tangible Net Worth.
                  Borrower shall maintain on a consolidated basis, measured
                  quarterly as of the last day of March, June, September and
                  December, a ratio of total liabilities under GAAP to Tangible
                  Net Worth of no more than 1.50:1 as of June 30, 1996,
                  September 30, 1996 and December 31, 1996; a ratio of total
                  liabilities under GAAP to Tangible Net Worth of no more than
                  1.25:1 as of March 31, 1997; and a ratio of total liabilities
                  under GAAP to Tangible Net Worth of no more than 1:1 from and
                  including June 30, 1997 through the remaining term of this
                  Agreement.

         26. CURRENT RATIO. Article 6 of the Credit Agreement is hereby amended
to add the following:

                           Section 6.18 Current Ratio. During the term of this
                  Agreement, Borrower shall maintain on a consolidated basis,
                  measured monthly as of the last day of each month commencing
                  June 30, 1996, a Current Ratio of no less than 1.7:1.

         27. INVESTMENTS AND SUBSIDIARIES. Section 7.4(a) of the Credit
Agreement is hereby deleted in its entirety and the following inserted therefor:

                           (a) The Borrower will not purchase or hold
                  beneficially any stock or other securities or evidences of
                  indebtedness of, make or permit to exist any loans or advances
                  to, or make any investment or acquire any interest whatsoever
                  in, any other Person, including specifically, but without
                  limitation, any partnership or joint venture, except for the
                  following:

                                  (i) Permitted Investments;

                                  (ii) advances in the form of progress
                             payments, prepaid rent or security deposits;

                                  (iii) loans to employees in an aggregate
                             amount outstanding at any time not to exceed
                             $25,000; and

                                      -17-
<PAGE>   18
                                  (iv) other uses mutually agreed upon in
                             writing by Borrower and Lender in their sole and
                             absolute discretion.

         28. CAPITAL EXPENDITURES. Section 7.10 of the Credit Agreement is
hereby deleted in its entirety and the following inserted therefor:

                           Section 7.10 Capital Expenditures. The Borrower will
                  not expend, or contract to expend, to purchase Capital Assets
                  more than $100,000 in Fiscal Year 1996 (excluding Borrower's
                  purchase of modular furniture having an approximate value of
                  $60,000); more than $500,000 in Fiscal Year 1997; and,
                  thereafter, during the term this Agreement, more than $200,000
                  in any Fiscal Year.

         29. ADDRESS FOR NOTICES, ETC. (a) For purposes of Section 9.3 of the
Credit Agreement, the address for notices, requests, demands or other
communications provided for under the Loan Documents to Lender shall be as
follows:

                        Norwest Bank Arizona, National Association
                        64 East Broadway
                        Tempe, Arizona   85282
                        Attn:   Mr. Jeffrey R. Wentzel, Vice President
                        Telecopier: (602) 644-8392

(b) Copies of all notices, requests, demands or other communications provided
for under Section 9.3 of the Credit Agreement or other communications provided
for under the Loan Documents to Borrower shall be delivered as follows:

                        Brown & Bain, P.A.
                        2901 North Central Avenue
                        P.O. Box 400
                        Phoenix, Arizona 85001-0400
                        Attn:   Frank M. Placenti, Esq.
                        Telecopier: (602) 351-8516

         30. FINANCING STATEMENT. For purposes of Section 9.4 of the Credit
Agreement, the name and address of the Secured Party shall be as follows:

                        Norwest Bank Arizona, National Association
                        64 East Broadway
                        Tempe, Arizona   85282
                        Attn:   Mr. Jeffrey R. Wentzel, Vice President

                                      -18-
<PAGE>   19
         31. COSTS AND EXPENSES. Section 9.7 of the Credit Agreement is hereby
deleted in its entirety and the following inserted therefor:

                           Section 9.7 Costs and Expenses. Borrower agrees to
                  pay to Lender on demand any and all costs, expenses and fees
                  (including reasonable attorneys' fees) incurred in enforcing
                  or attempting to recover payment of the amount due under this
                  Agreement, including, without limitation, negotiating,
                  documenting and otherwise pursuing or consummating any
                  modifications, extensions, compositions, renewals or other
                  similar transactions pertaining to this Agreement,
                  irrespective of the existence of a default, and including
                  costs, expenses and fees incurred before, after or
                  irrespective of whether suit is commenced and including costs,
                  expenses and fees incurred by Lender in any bankruptcy
                  proceedings (including, without limitation, efforts to modify
                  or vacate any automatic stay or injunction) or appellate
                  proceeding, and in the event suit or arbitration is brought to
                  enforce payment hereof, such costs, expenses and fees and all
                  other issues in such suit shall be determined by a court
                  sitting without a jury or by the arbitrator(s), as applicable.

         32. GOVERNING LAW; JURISDICTION, VENUE; WAIVER OF JURY TRIAL. Section
9.12 of the Credit Agreement is hereby deleted in its entirety and the following
inserted therefor:

                           Section 9.12 Arbitration; Waiver of Jury Trial.
                  EXCEPT FOR "CORE PROCEEDINGS" UNDER THE UNITED STATES
                  BANKRUPTCY CODE, THE PARTIES AGREE TO SUBMIT TO BINDING
                  ARBITRATION ALL CLAIMS, DISPUTES AND CONTROVERSIES BETWEEN
                  THEM, WHETHER IN TORT, CONTRACT OR OTHERWISE (AND THEIR
                  RESPECTIVE EMPLOYEES, OFFICERS, DIRECTORS, ATTORNEYS, AND
                  OTHER AGENTS) ARISING OUT OF OR RELATING TO IN ANY WAY THIS
                  CREDIT AGREEMENT. ANY ARBITRATION PROCEEDING WILL (A) PROCEED
                  IN PHOENIX, ARIZONA; (B) BE GOVERNED BY THE FEDERAL
                  ARBITRATION ACT (TITLE 9 OF THE UNITED STATES CODE); AND (C)
                  BE CONDUCTED IN ACCORDANCE WITH THE COMMERCIAL ARBITRATION
                  RULES OF THE AMERICAN ARBITRATION ASSOCIATION ("AAA"). THIS
                  ARBITRATION REQUIREMENT DOES NOT LIMIT THE RIGHT OF ANY PARTY
                  TO (I) FORECLOSE 

                                      -19-
<PAGE>   20
                  AGAINST REAL OR PERSONAL PROPERTY COLLATERAL OR SUE FOR AND
                  OBTAIN A DEFICIENCY JUDGMENT AFTER FORECLOSURE; (II) EXERCISE
                  SELF-HELP REMEDIES RELATING TO COLLATERAL OR PROCEEDS OF
                  COLLATERAL SUCH AS SETOFF OR REPOSSESSION; OR (III) OBTAIN
                  PROVISIONAL ANCILLARY REMEDIES SUCH AS REPLEVIN, INJUNCTIVE
                  RELIEF, ATTACHMENT OR THE APPOINTMENT OF A RECEIVER, BEFORE,
                  DURING OR AFTER THE PENDENCY OR ANY ARBITRATION PROCEEDING.
                  THIS EXCLUSION DOES NOT CONSTITUTE A WAIVER OF THE RIGHT OR
                  OBLIGATION OF ANY PARTY TO SUBMIT ANY DISPUTE TO ARBITRATION,
                  INCLUDING THOSE DISPUTES ARISING FROM THE EXERCISE OF THE
                  ACTIONS DETAILED IN CLAUSES (I), (II) AND (III) ABOVE. ANY
                  ARBITRATION PROCEEDING WILL BE BEFORE A SINGLE ARBITRATOR. THE
                  PARTIES SHALL USE REASONABLE EFFORTS TO AGREE UPON A SINGLE
                  ARBITRATOR WITHIN TEN (10) DAYS AFTER WRITTEN NOTICE FROM ONE
                  PARTY TO THE OTHER REQUESTING ARBITRATION. IF THE PARTIES ARE
                  UNABLE TO AGREE UPON AN ARBITRATOR WITHIN SUCH TEN (10) DAY
                  PERIOD, AT ANY TIME THEREAFTER EITHER PARTY MAY REQUIRE THAT
                  THE ARBITRATOR BE SELECTED ACCORDING TO THE COMMERCIAL
                  ARBITRATION RULES OF THE AAA. THE ARBITRATOR WILL BE A NEUTRAL
                  ATTORNEY WHO PRACTICES IN THE AREA OF COMMERCIAL OR BUSINESS
                  LAW. THE ARBITRATOR WILL DETERMINE WHETHER OR NOT AN ISSUE IS
                  ARBITRABLE AND WILL GIVE EFFECT TO THE STATUTES OF LIMITATION
                  IN DETERMINING ANY CLAIM. JUDGMENT UPON THE AWARD RENDERED BY
                  THE ARBITRATOR MAY BE ENTERED IN ANY COURT HAVING
                  JURISDICTION. IN ANY ARBITRATION PROCEEDING, THE ARBITRATOR
                  WILL DECIDE (BY DOCUMENTS ONLY OR WITH A HEARING AT THE
                  ARBITRATOR'S DISCRETION) ANY PRE-HEARING MOTIONS WHICH ARE
                  SIMILAR TO MOTIONS TO DISMISS FOR FAILURE TO STATE A CLAIM OR
                  MOTIONS FOR SUMMARY ADJUDICATION. IN ANY ARBITRATION
                  PROCEEDING, DISCOVERY WILL BE PERMITTED AND WILL BE GOVERNED
                  BY THE ARIZONA RULES OF CIVIL PROCEDURE. ALL 

                                      -20-
<PAGE>   21
                  DISCOVERY MUST BE COMPLETED NO LATER THAN 20 DAYS BEFORE THE
                  HEARING DATE AND WITHIN 180 DAYS OF THE COMMENCEMENT OF
                  ARBITRATION PROCEEDINGS. ANY REQUESTS FOR AN EXTENSION OF THE
                  DISCOVERY PERIODS, OR ANY DISCOVERY DISPUTES, WILL BE SUBJECT
                  TO FINAL DETERMINATION BY THE ARBITRATOR UPON A SHOWING THAT
                  THE REQUEST FOR DISCOVERY IS ESSENTIAL FOR THE PARTY'S
                  PRESENTATION AND THAT NO ALTERNATIVE MEANS FOR OBTAINING
                  INFORMATION IS AVAILABLE. THE ARBITRATOR SHALL AWARD COSTS AND
                  EXPENSES OF THE ARBITRATION PROCEEDING IN ACCORDANCE WITH THE
                  PROVISIONS OF THE CREDIT AGREEMENT. EXCEPT AS OTHERWISE
                  PROVIDED HEREIN, THIS AGREEMENT SHALL BE GOVERNED BY AND
                  CONSTRUED IN ACCORDANCE WITH THE LAWS OF THE STATE OF ARIZONA,
                  WITHOUT REGARD TO ITS CONFLICT OF LAWS RULES. IN THE EVENT
                  THAT LENDER EXERCISES ITS RIGHTS TO FORECLOSE AGAINST REAL OR
                  PERSONAL PROPERTY COLLATERAL OR OBTAIN PROVISIONAL ANCILLARY
                  REMEDIES SUCH AS REPLEVIN, INJUNCTIVE RELIEF, ATTACHMENT OR
                  THE APPOINTMENT OF A RECEIVER, THE PARTIES AGREE THAT ANY
                  LAWSUIT ARISING OUT OF ANY SUCH CONTROVERSY SHALL BE TRIED IN
                  A COURT OF COMPETENT JURISDICTION BY A JUDGE SITTING WITHOUT A
                  JURY.

                  ------------                                ------------
                  Initial                                     Initial

         33. COMPLIANCE CERTIFICATE. Exhibit E to the Credit Agreement is hereby
deleted in its entirety and replaced by Exhibit E attached to the First
Amendment, which is incorporated in the Agreement by this reference.

         34. PATENT APPLICATIONS. Exhibit F to the Credit Agreement is hereby
deleted in its entirety and replaced by Exhibit F attached to the First
Amendment, which is incorporated in the Agreement by this reference.

         35. MISCELLANEOUS.

                  (a) Arbitration Agreement; Waiver of Right to Jury Trial. The
Agreement contains an arbitration provision and waiver of right to jury trial.
In the 

                                      -21-
<PAGE>   22
event of any dispute arising out of or related to this Amendment, the provisions
of Section 9.12 of the Agreement shall apply.

                  (b) Voluntary Agreement. Borrower represents and warrants to
Lender that (i) it is, or has had the opportunity to be, represented by legal
counsel of its choice in regard to the transaction provided for by this
Amendment and that such counsel (if engaged) has explained the significance of
the terms, and the meaning and effect of this Amendment; (ii) it is fully aware
and clearly understands all of the terms and provisions contained in this
Amendment; (iii) it has voluntarily, with full knowledge and without coercion or
duress of any kind, entered into this Amendment and the documents executed in
connection with this Amendment; (iv) it is not relying on any representations,
either written or oral, express or implied, made to it by Lender other than as
set forth in this Amendment; and (v) the consideration received by Borrower to
enter into this Amendment and the arrangement contemplated by this Amendment has
been actual and adequate.

                  (c) Entire Agreement. This Amendment and the Loan Documents
constitute the entire agreement among the parties as to the agreements and
understandings contemplated by this Amendment. All parties to this Amendment
acknowledge that there are no agreements, understandings, warranties or
representations among the parties except as set forth in the Loan Documents and
this Amendment.

                  (d) Counterpart Execution. This Amendment may be executed in
counterparts, each of which shall be deemed an original document, and all of
which combined shall constitute a single document.

                  (e) Waiver. Neither this Amendment nor any of the provisions
hereof may be changed, waived, discharged or terminated, except by an instrument
in writing signed by the party against whom enforcement of the change, waiver,
discharge or termination is sought.

                  (f) Headings. Paragraph or other headings contained in this
Amendment are for reference purposes only and are not intended to affect in any
way the meaning or interpretation of this Amendment.

                  (g) Severability. If any clause or provision of this Amendment
is determined to be illegal, invalid, or unenforceable under any present or
future law by the final judgement of a court of competent jurisdiction, such
clause or provision shall be ineffective, but the remainder of this Amendment
will not be affected thereby.

                  (h) Binding Effect. All of the provisions of this Amendment
shall be binding upon and shall inure to the benefit of Borrower and Lender and
their permitted successors and assigns, including, without limitation, any
successor holder of any Note and any successor mortgagee/beneficiary under any
security document.

                                      -22-
<PAGE>   23
                  (i) Time of the Essence. Time is of the essence of each and
every provision under this Amendment.

                  (j) Amendment. Except as specifically set forth herein, the
Agreement and the other Loan Documents shall remain in full force and effect. In
the event of a conflict between the terms and provisions of this Amendment and
the terms and provisions of the Agreement, the terms and provisions of this
Amendment shall govern and control. This Amendment replaces and supersedes in
its entirety those certain letter agreements dated March 6, 1996 and April 11,
1996 between NBCI and Borrower. Nothing contained in this Amendment is intended
to or shall be construed as relieving any person or entity, whether a party to
this Amendment or not, of any of such person's or entity's obligations to
Lender.

                  (k) Power of Attorney. For purposes of compliance with Arizona
Revised Statutes Section 14-5503, Sections 3.2 and 6.11 of the Credit Agreement
and any other provisions in the Credit Agreement or Loan Documents granting a
power of attorney by Borrower to Lender are incorporated herein by this
reference.

                                      -23-
<PAGE>   24
         IN WITNESS WHEREOF, this Amendment is executed to be effective as of
the date first above written.

                                       BORROWER:

                                       MEDICIS PHARMACEUTICAL
                                       CORPORATION, a Delaware corporation
- ----------------------------------
Witness

                                       By:
                                          -------------------------------------
                                       Name:  Jonah Shacknai
                                            -----------------------------------
                                       Title:  Chairman of the Board
                                             ----------------------------------
                                       Execution Date:           May 29, 1996

                                       LENDER:

                                       NORWEST BANK ARIZONA, NATIONAL
                                       ASSOCIATION, a national banking
                                       association

                                       By:
                                          -------------------------------------
                                       Name:  Jeffrey R. Wentzel
                                            -----------------------------------
                                       Title:   Vice President
                                             ----------------------------------
                                       Execution Date:           May 29, 1996

                                      -24-
<PAGE>   25
STATE OF ARIZONA         )
                         ) ss.
County of Maricopa       )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jonah Shacknai, the
Chairman of the Board of MEDICIS PHARMACEUTICAL CORPORATION, a Delaware
corporation, on behalf of the corporation.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------



STATE OF ARIZONA         )
                         ) ss.
County of Maricopa       )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jeffrey R. Wentzel,
the Vice President of NORWEST BANK ARIZONA, NATIONAL ASSOCIATION, a national
banking association, on behalf of the banking association.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------

                                      -25-
<PAGE>   26
                                    EXHIBIT E

                             COMPLIANCE CERTIFICATE

         In accordance with our Credit and Security Agreement dated as of August
3, 1995, as amended (the "Credit Agreement"), attached are the financial
statements of Medicis Pharmaceutical Corporation (the "Borrower") as of and for
the month and year-to-date period ended ______________ __, 199_ (the "Current
Financials")

         I certify that the Current Financials have been prepared in accordance
with generally accepted accounting principles applied on a basis consistent with
the accounting practices reflected in the financial statements referred to in
Section 5.5 of the Credit Agreement, subject to year-end audit adjustments, if
applicable.

Defaults and Events of Default (check one)

    / /           I have no knowledge of the occurrence of any Default or Event
                  of Default under the Credit Agreement which has not previously
                  been reported to you and remedied.

    / /           Attached is a detailed description of all Defaults and Events
                  of Default of which I have knowledge and which have not
                  previously been reported to you and remedied.

         For the date and periods covered by the Current Financials, the
Borrower is in compliance with the covenants set forth in Sections 6.12, 6.16,
6.18 and 7.10 of the Credit Agreement, except as indicated below. The
calculations made to determine compliance are as follows:

<TABLE>
<CAPTION>
Covenant                             Actual             Requirement
<S>                                  <C>                <C>      
6.12     Tangible Net Worth          $__________                $________

6.16     Total Liabilities to

         Tangible Net Worth          ___________                _________

6.18     Current Ratio               ___________                _________

7.10     Capital Expenditures        $__________        Maximum $________
</TABLE>
<PAGE>   27
Date:____________________________, 199__

                                       MEDICIS PHARMACEUTICAL
                                       CORPORATION, a Delaware corporation

                                       By:_____________________________________
                                       Name:___________________________________
                                       Title:__________________________________

<PAGE>   1
                                                                EXHIBIT 10.73(b)

                      FIRST AMENDMENT TO PATENT COLLATERAL
                        ASSIGNMENT AND SECURITY AGREEMENT

         THIS FIRST AMENDMENT TO PATENT COLLATERAL ASSIGNMENT AND SECURITY
AGREEMENT (the "Amendment") is made as of this 29th day of May, 1996 by and
between MEDICIS PHARMACEUTICAL CORPORATION, a Delaware corporation ("Assignor"),
and NORWEST BANK ARIZONA, NATIONAL ASSOCIATION, a national banking association,
the successor-in-interest to Norwest Business Credit, Inc. ("Norwest Bank").

         WHEREAS, Assignor and Norwest Business Credit, Inc. ("NBCI") are
parties to that certain Patent Collateral Assignment and Security Agreement
dated as of August 3, 1995, which was filed with the United States Department of
Commerce Patent and Trademark Office on August 17, 1995 in Reel/Frame: 7596/0504
(the "Agreement");

         WHEREAS, NBCI has assigned, and Norwest Bank has assumed, all of NBCI's
right, title, interest, privileges, obligations and liabilities under the
Agreement;

         WHEREAS, Assignor has filed additional patents with the United States
Department of Commerce Patent and Trademark Office since August 17, 1995, which
patents are intended to be collateral security for the obligations of Assignor
to Assignee; and

         WHEREAS, Assignor and Norwest Bank desire to amend the Agreement as
provided herein;

         NOW, THEREFORE, in consideration of the premises and the mutual
covenants contained herein and other good and valuable consideration, the
receipt and sufficient of which are hereby acknowledged, Assignor and Norwest
Bank, intending to be legally bound, agree as follows:

         1. Interpretation. Except as otherwise defined herein, all capitalized
terms used herein shall have the meanings ascribed thereto in the Agreement.

         2. Assignee. All references to "Assignee" in the Agreement shall
hereafter refer to Norwest Bank Arizona, National Association, a national
banking association.

         3. Recitals. The Section of the Agreement entitled "RECITALS" is hereby
amended to add the following:

                           D. On or about May 29, 1996, Norwest Business Credit,
                  Inc. assigned and transferred to Norwest Bank Arizona,
                  National Association, all of its right, title, interest,
                  privileges, obligations and liabilities under the Note and
                  Loan Agreement and all of the other agreements and documents
                  evidencing, securing or otherwise relating
<PAGE>   2
                  thereto, including, without limitation, this Agreement.

                           E. Assignor and Norwest Bank Arizona, National
                  Association, have concurrently herewith executed and delivered
                  that certain First Amendment to Loan and Security Agreement
                  dated as of May 29, 1996 which provides, among others, for an
                  additional $3,000,000 multiple advance loan from Norwest Bank
                  Arizona, National Association, to Assignor, subject to and on
                  the terms and conditions contained therein, which loan is
                  evidenced by that certain Multiple Advance Note dated May 29,
                  1996 from Assignor to Norwest Bank Arizona, National
                  Association, in the original principal amount of $3,000,000,
                  as it may hereafter be amended, modified, restated, extended,
                  renewed and/or consolidated from time to time (the "Term
                  Note").

         4. Obligations Secured. Section 2(a) of the Agreement is hereby deleted
and the following inserted therefor:

                           (a) The payment of indebtedness in the total
                  principal amount of up to $5,000,000, with interest thereon,
                  evidenced by the Note and the Term Note.

         5. Patent Schedule. Schedule A attached to the Agreement is hereby
deleted in its entirety and replaced by Schedule A attached to the First
Amendment to Patent Collateral Assignment and Security Agreement dated as of May
29, 1996 between Assignor and Assignee, which is incorporated in the Agreement
by this reference.

         6. Governing Law. This Amendment shall be governed by and construed in
accordance with the laws of the State of Arizona.

         7. Counterparts. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original and all of which
combined shall constitute one and the same instrument.

         8. Successors and Assigns. This Amendment shall inure to the benefit of
and be binding upon the parties hereto and their respective successors and
permitted assigns.

         9. Amendment. Except as otherwise amended hereby, all of the terms and
provisions of the Agreement shall remain in full force and effect.

         10. Power of Attorney. For purposes of compliance with Arizona Revised
Statutes Section 14-5503, Section 13 of the Agreement and any other provisions
in the Agreement granting a power of attorney by Assignor to NBCI or Norwest
Bank are incorporated herein by this reference.

                                       -2-
<PAGE>   3
         IN WITNESS WHEREOF, this Amendment is executed as of the date first
above written.

                                       ASSIGNOR:

                                       MEDICIS PHARMACEUTICAL
                                       CORPORATION, a Delaware corporation
__________________________________
Witness

                                       By:
                                          -------------------------------------
                                       Name:    Jonah Shacknai
                                            -----------------------------------
                                       Title:   Chairman of the Board
                                             ----------------------------------

                                       NORWEST BANK:

                                       NORWEST BANK ARIZONA, NATIONAL
                                       ASSOCIATION, a national banking
                                       association

                                       By:
                                          -------------------------------------
                                       Name:  Jeffrey R. Wentzel
                                            -----------------------------------
                                       Title: Vice President
                                             ----------------------------------

                                       -3-
<PAGE>   4
STATE OF ARIZONA          )
                          ) ss.
County of Maricopa        )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jonah Shacknai, the
Chairman of the Board of MEDICIS PHARMACEUTICAL CORPORATION, an Arizona
corporation, on behalf of the corporation.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------





STATE OF ARIZONA         )
                         ) ss.
County of Maricopa       )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jeffrey R. Wentzel,
the Vice President of NORWEST BANK ARIZONA, NATIONAL ASSOCIATION, a national
banking association, on behalf of the banking association.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------

                                       -4-

<PAGE>   1
                                                                EXHIBIT 10.74(b)
 
                         FIRST AMENDMENT TO TRADEMARK,
                      TRADENAME AND SERVICE MARK COLLATERAL
                        ASSIGNMENT AND SECURITY AGREEMENT

         THIS FIRST AMENDMENT TO TRADENAME, TRADEMARK AND SERVICE MARK
COLLATERAL ASSIGNMENT AND SECURITY AGREEMENT (the "Amendment") is made as of
this 29th day of May, 1996 by and between MEDICIS PHARMACEUTICAL CORPORATION, a
Delaware corporation ("Assignor"), and NORWEST BANK ARIZONA, NATIONAL
ASSOCIATION, a national banking association, the successor-in-interest to
Norwest Business Credit, Inc. ("Norwest Bank").

         WHEREAS, Assignor and Norwest Business Credit, Inc. ("NBCI") are
parties to that certain Trademark, Tradename and Service Mark Collateral
Assignment and Security Agreement dated as of August 3, 1995, which was filed
with the United States Department of Commerce Patent and Trademark Office on
August 17, 1995 in Reel/Frame: 1382/0782 (the "Agreement");

         WHEREAS, NBCI has assigned, and Norwest Bank has assumed, all of NBCI's
right, title, interest, privileges, obligations and liabilities under the
Agreement;

         WHEREAS, Assignor has filed additional trademarks, tradenames and/or
service marks with the United States Department of Commerce Patent and Trademark
Office since August 17, 1995, which trademarks, tradenames and/or service marks
are intended to be collateral security for the obligations of Assignor to
Assignee; and

         WHEREAS, Assignor and Norwest Bank desire to amend the Agreement as
provided herein;

         NOW, THEREFORE, in consideration of the premises and the mutual
covenants contained herein and other good and valuable consideration, the
receipt and sufficient of which are hereby acknowledged, Assignor and Norwest
Bank, intending to be legally bound, agree as follows:

         1. Interpretation. Except as otherwise defined herein, all capitalized
terms used herein shall have the meanings ascribed thereto in the Agreement.

         2. Lender. All references to "Lender" in the Agreement shall hereafter
refer to Norwest Bank Arizona, National Association, a national banking
association.

         3. Recitals. The Section of the Agreement entitled "RECITALS" is hereby
amended to add the following:

                           D. On or about May 29, 1996, Norwest Business Credit,
                  Inc. assigned and transferred to Norwest Bank Arizona,
                  National Association, all of its right, title, interest,
<PAGE>   2
                  privileges, obligations and liabilities under the Note and
                  Loan Agreement and all of the other agreements and documents
                  evidencing, securing or otherwise relating thereto, including,
                  without limitation, this Agreement.

                           E. Assignor and Norwest Bank Arizona, National
                  Association, have concurrently herewith executed and delivered
                  that certain First Amendment to Loan and Security Agreement
                  dated as of May 29, 1996 which provides, among others, for an
                  additional $3,000,000 multiple advance loan from Norwest Bank
                  Arizona, National Association, to Assignor, subject to and on
                  the terms and conditions contained therein, which loan is
                  evidenced by that certain Multiple Advance Note dated May 29,
                  1996 from Assignor to Norwest Bank Arizona, National
                  Association, in the original principal amount of $3,000,000,
                  as it may hereafter be amended, modified, restated, extended,
                  renewed and/or consolidated from time to time (the "Term
                  Note").

         4. Obligations Secured. Section 2(a) of the Agreement is hereby deleted
and the following inserted therefor:

                           (a) The payment of indebtedness in the total
                  principal amount of up to $5,000,000, with interest thereon,
                  evidenced by the Note and the Term Note.

         5. Tradename, Trademark and Service Mark Schedule. Schedule A attached
to the Agreement is hereby deleted in its entirety and replaced by Schedule A
attached to the First Amendment to Tradename, Trademark and Service Mark
Collateral Assignment and Security Agreement dated as of May 29, 1996 between
Assignor and Assignee, which is incorporated in the Agreement by this reference.

         6. Governing Law. This Amendment shall be governed by and construed in
accordance with the laws of the State of Arizona.

         7. Counterparts. This Amendment may be executed in one or more
counterparts, each of which shall be deemed an original and all of which
combined shall constitute one and the same instrument.

         8. Successors and Assigns. This Amendment shall inure to the benefit of
and be binding upon the parties hereto and their respective successors and
permitted assigns.

         9. Amendment. Except as otherwise amended hereby, all of the terms and
provisions of the Agreement shall remain in full force and effect.

                                      -2-
<PAGE>   3
         10. Power of Attorney. For purposes of compliance with Arizona Revised
Statutes Section 14-5503, Section 13 of the Agreement and any other provisions
in the Agreement granting a power of attorney by Assignor to Lender are
incorporated herein by this reference.

         IN WITNESS WHEREOF, this Amendment is executed as of the date first
above written.

                                       ASSIGNOR:

                                       MEDICIS PHARMACEUTICAL
                                       CORPORATION, a Delaware corporation
- ----------------------------------
Witness

                                       By:
                                          -------------------------------------
                                       Name:    Jonah Shacknai
                                            -----------------------------------
                                       Title:  Chairman of the Board
                                             ----------------------------------

                                       NORWEST BANK:

                                       NORWEST BANK ARIZONA, NATIONAL
                                       ASSOCIATION, a national banking
                                       association

                                       By:
                                          -------------------------------------
                                       Name:  Jeffrey R. Wentzel
                                            -----------------------------------
                                       Title:   Vice President
                                             ----------------------------------

                                       -3-
<PAGE>   4
STATE OF ARIZONA       )
                       ) ss.
County of Maricopa     )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jonah Shacknai, the
Chairman of the Board of MEDICIS PHARMACEUTICAL CORPORATION, an Arizona
corporation, on behalf of the corporation.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------



STATE OF ARIZONA       )
                       ) ss.
County of Maricopa     )

                  The foregoing instrument was acknowledged before me, the
undersigned notary public, this 29th day of May, 1996, by Jeffrey R. Wentzel,
the Vice President of NORWEST BANK ARIZONA, NATIONAL ASSOCIATION, a national
banking association, on behalf of the banking association.

                                       ---------------------------------
                                       Notary Public

My Commission Expires:

- ----------------------

                                       -4-

<PAGE>   1

                                                                EXHIBIT 10.75


                  ASSIGNMENT AND ASSUMPTION OF LOAN DOCUMENTS

        THIS ASSIGNMENT AND ASSUMPTION OF LOAN DOCUMENTS (the "Assignment") is
dated as of the 29th day of May, 1996 by and between NORWEST BUSINESS CREDIT,
INC., a Minnesota corporation ("Assignor"), and NORWEST BANK ARIZONA, NATIONAL
ASSOCIATION, a national banking association ("Assignee").

        WHEREAS, Assignor and Medicis Pharmaceutical Corporation ("Borrower")
entered into that certain Credit and Security Agreement dated as of August 3,
1995, as modified by letter agreements dated March 6, 1996 and April 11, 1996
(collectively, the "Credit Agreement"), pursuant to which Assignor agreed to
make available to Borrower, on a revolving basis, a sum not to exceed
$2,000,000 (the "Revolving Loan");

        WHEREAS, the following documents evidence, secure or relate to the
Revolving Loan (the "Loan Documents"):

                (a)  The Credit Agreement.

                (b)  Promissory Note dated August 3, 1995 from Borrower to
Assignor in an amount not to exceed $2,000,000 (the "Revolving Note").

                (c)  UCC-1 Financing Statement from Borrower in favor of
Assignor filed on July 12, 1995 in File No. 9519960707, Records of California
Secretary of State.

                (d)  UCC-1 Financing Statement from Borrower in favor of
Assignor filed on July 18, 1995 in File No. 2157162, Records of Kansas
Secretary of State.

                (e)  UCC-1 Financing Statement from Borrower in favor of
Assignor filed on July 12, 1995 in File No. 140451, Records of New York
Secretary of State.

                (f)  UCC-1 Financing Statement from Borrower in favor of
Assignor filed on July 5, 1995 in File No. 837751, Records of Arizona Secretary
of State.

                (g)  Collateral Account Agreement dated as of August 3, 1995
between Assignor and Borrower.

                (h)   Patent Collateral Assignment and Security Agreement dated
as of August 3, 1995 between Assignor and Borrower.

                (i)  Trademark, Tradename and Service Mark Collateral
Assignment and Security Agreement dated as of August 3, 1995 between Assignor
and Borrower.

                (j)  Agreement as to Lockbox Services dated as of August 3,
1995 between Assignor and Borrower.


<PAGE>   2
                (k) Intercreditor Agreement dated as of August 3, 1995 between
Assignor and the Community Economic Development Corporation.

                (l) Landlord's Subordination, Disclaimer and Consent dated as
of August 3, 1995 among Assignor, Borrower and Londen Center L.L.C.

                (m) Tri-Party Agreement among Assignor, Borrower and USCO
Distribution Services, Inc.

                (n) Any and all collateral accounts, lock boxes and funds and
documents contained therein.

                (o) All other instruments, agreements or documents of any kind
affecting or relating to the Revolving Loan executed or delivered in connection
with or as security for the Revolving Loan, including, without limitation, any
and all title insurance policies, insurance policies and certificates,
collateral reports, appraisals, UCC lien, litigation and judgment searches,
financing statements and attorneys' opinion letters.

                (p) Assignor's credit file and transaction history, including,
without limitation, all written correspondence to and from Borrower.

        WHEREAS, Assignor desires to assign, and Assignee desires to assume,
all of Assignor's right, title, interest, privileges, obligations and
liabilities under the Loan Documents, subject to and on the terms and
conditions contained herein;

        NOW, THEREFORE, in consideration of TEN AND NO/100 DOLLARS ($10.00)
and other good and valuable consideration, the receipt and sufficiency of which
are hereby acknowledged, Assignor and Assignee agrees as follows:

        1. Assignment and Transfer of Loan. Assignor hereby grants, bargains,
sells, transfers, assigns, releases and sets over unto Assignee, its successors
and assigns, forever, the Assignor's interest in and to the Loan Document and
Assignor shall deliver all of the original copies of the Loan Document in
Assignor's possession or control.

        2. Authorization to Perform. Assignor hereby directs and authorizes the
parties to any of the Loan Documents to perform any obligations heretofore
owned to Assignor thereunder for the benefit, and at the direction, of Assignee
from and after the date hereof, and the delivery of a copy of this Assignment to
such party may be relied upon by any such party in complying with this
direction and authorization.

        3. Assumption. Assignee hereby agrees to assume and perform all
obligations and agreements of Assignor accruing under the Loan Documents from
and after the date hereof.

        4. Assignor's Representations and Warranties. Assignor represents,
warrants and covenants with and to Assignee that as of the date of this
Assignment:

                                      -2-


<PAGE>   3
        (a)     Assignor is the legal and beneficial owner and holder of the
Revolving Loan, and Assignor has not previously assigned, transferred, conveyed,
hypothecated, encumbered or otherwise transferred its interest in the
Revolving Loan or the Loan Documents.

        (b)     Assignor has the right, power, legal capacity, and authority to
execute and deliver this Assignment and to consummate the transactions
contemplated by the Assignment. This Assignment has been duly and validly
executed and delivered by Assignor, constitutes the valid, legal and binding
agreement of Assignor, and is enforceable against Assignor in accordance with
its terms. Except as set forth in the Loan Documents, no approval of any person
or entity is required for the execution and delivery of this Assignment by
Assignor or the consummation of any of the transactions contemplated by the
Assignment. 

        (c)     Assignor has not received any notice, and has no actual
knowledge, of the occurrence and continuation of any default or event of
default (or other event which, with the passage of time, the giving of notice,
or both, would constitute an event of default) by Borrower under any of the Loan
Documents. 

        (d)     There is no contract, agreement, instrument, document, or
written or oral understanding between Assignor and Borrower which amends,
modifies, waives or rearranges any of the Loan Documents or which diminishes
or impairs the obligation of the Borrower to pay the indebtedness evidenced by
the Revolving Note or to perform fully the obligations of such Borrower in
strict accordance with the Loan Documents, or which impairs, subordinates, or
diminishes the liens created by the Loan Documents, or which would permit the
Borrower to void or avoid its obligations in whole or in part.

        (e)     Except for the Credit Agreement, Borrower is not indebted to
Assignor and Assignor has no obligation or commitment to make any loans or
advance any funds to or for the benefit of Borrower. Except for the prorated
Minimum Interest Charge (including the unused fee described in Section 2.11(b)
of the Credit Agreement) of $24,843.36; and the collateral examination fee of
$2,300, there is no principal or interest, or fees, costs or charges, due
Assignor by Borrower under the Credit Agreement.

        (f)     To Assignor's actual knowledge, there is no action, suit or
proceeding pending, or threatened or asserted, against Assignor affecting the
Revolving Loan, at law or in equity or before or by any federal, state,
municipal or other governmental department, commission, board, bureau, agency
or instrumentality, domestic or foreign.

        (g)     Assignor has not received any notice that the Borrower has
failed to file or has improperly filed any tax return or report required to be
filed by the Borrower, or that the Borrower has failed to pay all taxes,
charges and assessments due and payable.

   5.   Assignee's Representations and Warranties.  Assignee represents,
warrants and covenants with and to Assignor that:

        (a)     Assignee has the right, power, legal capacity, and authority
to execute and deliver this Assignment and to consummate the transactions
contemplated by the Assignment. This Assignment has been duly and validly
executed and delivered by Assignee, constitutes the

                                      -3-
        
<PAGE>   4
valid, legal and binding agreement of Assignee, and is enforceable against
Assignee in accordance with its terms. Except as set forth in the Loan
Documents, no approval of any person or entity is required for the execution
and delivery of this Assignment by Assignee or the consummation of any of the
transactions contemplated by the Assignment.

        6.  Payment to Assignor.  Assignor and Assignee agree that
notwithstanding any terms of this Assignment to the contrary, the sums owing to
Assignor set forth in paragraph 4(e) above shall be paid to Assignor by
Borrower in good funds as a condition precedent to the effectiveness of this
Assignment.

        7.  Severability of Provisions.  Whenever possible, each provision of
this Assignment shall be interpreted in such manner as to be valid under
applicable law, but if any provision of this Assignment shall be invalid or
prohibited hereunder, such provision shall be ineffective to the extent of such
prohibition or invalidation, which shall not invalidate the remainder of such
provisions or the remaining provisions of this Assignment.

        8.  Governing Law.  This Assignment shall be governed by and construed
in accordance with the laws of the State of Arizona, without giving effect to
its conflict of laws rules.

        9.  Enforcement.  In the event of litigation involving this Assignment,
the unsuccessful party shall pay to the prevailing party all costs of suit,
including reasonable attorneys' fees.

       10.  Continuation of Provisions.  The representations and warranties
contained herein shall be effective on the date hereof and shall survive the
execution and delivery of this Assignment.

       11.  Entire Agreement.  This Assignment contains the entire agreement of
the parties hereto with respect to the matters covered hereby and supersedes
all prior arrangements and understandings between the parties, and no other
agreement, statement or promise made by either party hereto which is not
contained herein shall be binding or valid.

       12.  Counterparts.  This Assignment may be executed in one or more
counterparts, each of which shall be deemed an original and all of which
together shall be considered one and the same instrument.

       13.  Binding Effect.  This Assignment shall be binding upon and shall
inure to the benefit Assignor, Assignee and their successors and assigns.

       14.  Further Assurances.  Assignor agrees to execute such separate
assignments of the Loan Documents or other documents as Assignee may reasonably
require for the purpose of giving separate notice of the assignments herein at
the sole expense of Assignee, and Assignee shall reimburse Assignor for fees
and costs incurred by Assignor in the review and execution of such documents.


                                      -4-


<PAGE>   5
        IN WITNESS WHEREOF, the parties have executed this Assignment as of the
day and year first above written.

                                        ASSIGNEE:

                                        NORWEST BANK ARIZONA, NATIONAL
                                        ASSOCIATION, a national banking
                                        association


                                        By: /s/ Jeffrey R. Wentzel
                                            -----------------------------------
                                            Name:   Jeffrey R. Wentzel
                                            Title:  Vice President

                                        ASSIGNOR:


                                        NORWEST BUSINESS CREDIT, INC.,  a
                                        Minnesota corporation


                                        By: /s/ Peter J. Lowney
                                            -----------------------------------
                                            Name:   Peter J. Lowney
                                            Title:  Assistant Vice President


ACKNOWLEDGEMENT OF MEDICIS:


By: /s/ Jonah Shacknai
    -----------------------------------
    Name:   Jonah Shacknai
    Title:  Chairman of the Board

                                      -5-


                                        

<PAGE>   1
                                                                   EXHIBIT 10.76

                              MULTIPLE ADVANCE NOTE

$3,000,000                                                     Phoenix, Arizona
                                                                   May 29, 1996

         For value received, the undersigned, Medicis Pharmaceutical
Corporation, a Delaware corporation (the "Borrower"), hereby promises to pay on
or before July 31, 1997 to the order of Norwest Bank Arizona, National
Association, a national banking association (the "Lender"), at its main office
in Phoenix, Arizona, or at any other place designated at any time by the holder
hereof, in lawful money of the United States of America and in immediately
available funds, the principal sum of Three Million Dollars ($3,000,000) or, if
less, the aggregate unpaid principal amount of all advances made by the Lender
to the Borrower hereunder, together with interest on the principal amount
hereunder remaining unpaid from time to time, computed on the basis of the
actual number of days elapsed and a 360-day year, from the date hereof until
this Note is fully paid at the rate from time to time in effect under the Credit
and Security Agreement dated as August 3, 1995 by and between Norwest Business
Credit, Inc. and the Borrower, as amended (the "Credit Agreement"). Except as
otherwise defined herein, all capitalized terms used herein shall have the
meanings ascribed thereto in the Credit Agreement.

         The principal hereof and interest accruing thereon shall be due and
payable as provided in the Credit Agreement. This Note may be prepaid only in
accordance with the Credit Agreement.

         Provided that no Default or Event of Default has occurred and is
continuing on July 31, 1997, the then outstanding principal balance of this Note
shall be payable in accordance with Section 2.13 of the Credit Agreement. At the
request of Lender, Borrower shall execute and deliver a replacement promissory
note on or before July 31, 1997 in accordance with Section 2.13 of the Credit
Agreement.

         This Note is issued pursuant, and is subject, to the Credit Agreement,
which provides, among other things, for acceleration hereof. This Note is the
Term Note referred to in the Credit Agreement.

         This Note is secured, among other things, pursuant to the Credit
Agreement and the Security Documents (as defined in the Credit Agreement), and
may now or hereafter be secured by one or more other security agreements,
mortgages, deeds of trust, assignments or other instruments or agreements.

         The Borrower hereby agrees to pay all costs of collection, including
attorneys' fees and legal expenses in the event this Note is not paid when due,
whether or not legal proceedings are commenced.
<PAGE>   2
         The Borrower agrees that the interest rate contracted for includes the
interest rate set forth in the Credit Agreement plus any other charges or fees
set forth herein and costs and expenses incident to this transaction paid by the
Borrower to the extent the same are deemed interest under applicable law.

         Presentment or other demand for payment, notice of dishonor and protest
are expressly waived.

         IN WITNESS WHEREOF, this Note is executed and delivered as of the date
first above written.

                                       MEDICIS PHARMACEUTICAL
                                       CORPORATION, a Delaware corporation

                                       By:
                                          -------------------------------------
                                       Name:  Jonah Shacknai
                                            -----------------------------------
                                       Title:   Chairman of the Board
                                             ----------------------------------

<PAGE>   1
                                                                   Exhibit 21.1

                  SUBSIDIARIES OF MEDICIS PHARMACEUTICAL CORP.

<TABLE>
<CAPTION>
NAME                            JURISDICTION OF INCORPORATION           OWNERSHIP
- ----                            -----------------------------           ---------
<S>                                     <C>                               <C>
Medicis Dermatologics, Inc.              Delaware                          100%
</TABLE>


                                           

<PAGE>   1
 
                                                                    EXHIBIT 23.1
 
               CONSENT OF ERNST & YOUNG, LLP INDEPENDENT AUDITORS
 
     We consent to the incorporation by reference in the Registration Statement
(Form S-8 No. 33-45573) pertaining to the 1988 and 1990 Stock Option Plans and
the Registration Statement (Form S-8 No. 33-88590) pertaining to the 1992 Stock
Option Plan of Medicis Pharmaceutical Corporation of our report dated August 2,
1996 with respect to the consolidated financial statements and schedule of
Medicis Pharmaceutical Corporation included in the Annual Report (Form 10-K) for
the year ended June 30, 1996.
 
                                          ERNST & YOUNG, LLP
 
Phoenix, Arizona
August 15, 1996
 

<TABLE> <S> <C>

<ARTICLE> 5
       
<S>                             <C>
<PERIOD-TYPE>                   YEAR
<FISCAL-YEAR-END>                          JUN-30-1996
<PERIOD-START>                             JUL-01-1995
<PERIOD-END>                               JUN-30-1996
<CASH>                                       7,956,050
<SECURITIES>                                         0
<RECEIVABLES>                                5,890,704
<ALLOWANCES>                                   680,000
<INVENTORY>                                  2,080,014
<CURRENT-ASSETS>                            18,985,679
<PP&E>                                         506,544
<DEPRECIATION>                                 100,897
<TOTAL-ASSETS>                              26,312,800
<CURRENT-LIABILITIES>                        6,585,131
<BONDS>                                        116,580
                                0
                                        627
<COMMON>                                        97,183
<OTHER-SE>                                  19,361,842
<TOTAL-LIABILITY-AND-EQUITY>                26,312,800
<SALES>                                     25,309,743
<TOTAL-REVENUES>                            25,309,743
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