MEDICIS PHARMACEUTICAL CORP
8-K, 1999-04-23
PHARMACEUTICAL PREPARATIONS
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                               UNITED STATES
                    SECURITIES AND EXCHANGE COMMISSION


                          Washington, D.C. 20549


                                 FORM 8-K


                              CURRENT REPORT


                  Pursuant to Section 13 or 15(d) of the
                      Securities Exchange Act of 1934


             Date of Earliest Event Reported:  April 19, 1999



                    MEDICIS PHARMACEUTICAL CORPORATION
          (Exact name of registrant as specified in its charter)


      Delaware                    0-18443                 52-1574808
  (State or other               (Commission             (IRS Employer
  jurisdiction of               file number)         Identification No.)
   incorporation)

                         4343 East Camelback Road
                          Phoenix, Arizona 85018
           (Address of principal executive offices)  (Zip code)

            Registrant's telephone number, including area code:
                              (602) 808-8800


       (Former Name or Former Address, if Changed Since Last Report)


==========================================================================





Item 5.   Other Events

     Effective as of April 1, 1999, the Registrant purchased all the issued
and outstanding common stock of Ucyclyd Pharma, Inc. ("Ucyclyd"), a
Maryland corporation (the "Acquisition") pursuant to a Stock Purchase
Agreement by and among the Registrant, Ucyclyd and the Sellers signatory
thereto.  A description of the Acquisition is contained in the press
release attached hereto as Exhibit 99.1 and incorporated herein by
reference.

Item 7.   Financial Statements and Exhibits

          (c)  Exhibits

               The following Exhibits are filed as part of this report:

               99.1 -    Press Release dated April 19, 1999.




                                 SIGNATURE

     Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by
the undersigned thereunto duly authorized.

                              MEDICIS PHARMACEUTICAL CORPORATION


                              /S/ MARK A. PRYGOCKI, SR.
                              -----------------------------------
                              Mark A. Prygocki, Sr.
                              Chief Financial Officer

Date:  April 22, 1999.





                               EXHIBIT INDEX


Exhibit
Number         Description
- -------        -----------

 99.1    --   Press Release dated April 19, 1999.




                                     EXHIBIT 99.1

                                               FOR IMMEDIATE RELEASE


CONTACT:
Libby Retherford, Director, Corporate Communications,
(602) 808-3854


                     MEDICIS PHARMACEUTICAL CORPORATION ANNOUNCES
                           ACQUISITION OF UCYCLYD PHARMA INC.


PHOENIX---April 19, 1999---Medicis Pharmaceutical Corporation (NYSE:MRX)
today announced the strategic acquisition of Ucyclyd Pharma Inc., a
privately held pharmaceutical company based in Baltimore, for approximately 
$23.4 million in cash.  Under terms of the agreement, Medicis will pay $15 
million at the close of the transaction; $5.7 million on the first anniversary 
of the closing date, subject to certain manufacturing conditions; and $2.7 
million upon regulatory approval of a line extension.  Medicis will also 
receive certain technologies that will further enhance the Company's 
research and development pipeline.

Ucyclyd Pharma's principal product is the orphan drug BUPHENYL(TM), the
only approved drug substance indicated in the treatment of Urea Cycle
Disorders (UCDs).  UCDs are a group of rare genetic metabolic disorders where 
one or more of the key enzymes needed to eliminate waste nitrogen from the body
are missing. Most UCD patients are required to maintain BUPHENYL(TM) therapy
for the duration of their lives.  Typically, this disorder is treated by 
pediatric specialists. Historically, this product has had approximately $6 
million in annual sales.

"We are pleased to announce this strategic acquisition and the Company's
entrance into the specialty niche orphan drug market," said Jonah Shacknai,
Chairman and Chief Executive Officer.  "This acquisition contributes strong
gross profit margins and will be predictably accretive to earnings.  Urea
Cycle Disorders present an interesting market niche requiring little
promotional effort and a lack of management dilution.  The profitability of 
this transaction will help to fund additional research and development 
efforts."

Medicis is the leading independent pharmaceutical company in the United
States focusing primarily on the treatment of dermatological conditions.
Medicis develops and markets leading products for major segments within
dermatology including acne, psoriasis, eczema, rosacea, dandruff and
cosmesis (improvement in the texture and appearance of skin).  Primary 
products include prescription brands (all of which are registered trademarks 
of Medicis) DYNACIN, TRIAZ, LUSTRA, LIDEX, SYNALAR, LOPROX, TOPICORT, NOVACET, 
ZONALON and A/T/S, and over-the-counter brands ZOSTRIX, ESOTERICA and 
THERAPLEX.

Except for historical information, this news release contains certain
forward-looking statements that involve risks and uncertainties which may
cause actual results to differ materially from the statements made, including 
the Company's dependence on sales of key products, uncertainty of future
financial results and fluctuations in operating results, dependence on the 
Company's acquisition strategy, new product introductions and other risks 
described from time to time in the Company's SEC filings. These forward-looking
statements represent the judgment of the Company, as of the date of this 
release, and Medicis disclaims any intent or obligation to update these 
forward-looking statements.


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