HOLOGIC INC
DEF 14A, 1998-01-13
X-RAY APPARATUS & TUBES & RELATED IRRADIATION APPARATUS
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                               18
                                
                          SCHEDULE 14A
                         (Rule 14a-101)
             INFORMATION REQUIRED IN PROXY STATEMENT
                                
                    SCHEDULE 14A INFORMATION
   Proxy Statement Pursuant to Section 14(a) of the Securities
                      Exchange Act of  1934
                                
Filed by the registrant [X]
Filed by a party other than the registrant [   ]
Check the appropriate box:
[   ]  Preliminary proxy statement
[X]  Definitive proxy statement
[   ]  Definitive additional materials
[   ]  Soliciting material pursuant to Rule 14a-11(c) or Rule 14a-
12

                          Hologic, Inc.
        (Name of Registrant as Specified in its Charter)
                                
                          Hologic, Inc.
           (Name of Person(s) Filing Proxy Statement)

Payment of filing fee (Check the appropriate box):

[X]   No fee required.
[   ]  Fee computed on table below per Exchange Act Rules 14a-
6(i)(1) and 0-11.
     1)  Title of each class of securities to which transaction
         applies:
     _____________________________________________

     2)  Aggregate number of securities to which transaction
         applies:
     _____________________________________________

     3)  Per unit price or other underlying value of transaction
         computed pursuant to Exchange Act Rule 0-11 [1]:
     _____________________________________________

     4)  Proposed maximum aggregate value  of transaction:

     -----------------------------------------------------

     5)  Total fee paid:

     ------------------------------------------------
   
 [  ]   Fee paid previously with preliminary materials.
________
1 Set forth the amount on which the filing fee is calculated and
state how it was determined.

[   ]  Check box if any part of the fee is offset as provided by
Exchange Act Rule 0-11(a)(2) and identify the filing for which
the offsetting fee was paid previously.  Identify the previous
filing by registration statement number, or the Form or Schedule
and the date of its filing.
     1)  Amount previously paid:

     ------------------------------------------------
     2)  Form, schedule or registration statement no.:

     -------------------------------------------------
     3)  Filing party:
     
     -------------------------------------------------
     4)  Date filed:

     --------------------------------------------------
                                
                          HOLOGIC, INC.
                          ____________
                                
            NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                        FEBRUARY 24, 1998

TO THE STOCKHOLDERS OF HOLOGIC, INC.

   NOTICE  IS  HEREBY  GIVEN  that  the  Annual  Meeting  of  the
Stockholders  of  Hologic,  Inc.,  a  Delaware  corporation  (the
"Company"), will be held on Tuesday, February 24, 1998  at  10:00
a.m.,  local  time,  at the offices of the Company,  590  Lincoln
Street, Waltham, Massachusetts 02154 for the following purposes:

      1.    To elect seven (7) directors to serve for the ensuing
            year and until their successors are duly elected.

      2.   To ratify the appointment of Arthur Andersen LLP as
           independent public accountants of the Company.

      3.   To transact such other business as may properly come
           before the meeting or any adjournment thereof.

  The foregoing items of business are more fully described in the
Proxy Statement accompanying this Notice.

  Only stockholders of record at the close of business on January
5,  1998 are entitled to notice of and to vote at the meeting and
any  continuation  or adjournment thereof.  All stockholders  are
cordially  invited  to  attend the Annual Meeting.   However,  to
assure your representation at the meeting, you are urged to mark,
sign,  date and return the enclosed proxy as promptly as possible
in  the  postage-paid envelope enclosed for  that  purpose.   Any
stockholder attending the meeting may vote in person even  if  he
or she returned a proxy.

                              By order of the Board of Directors

                              Lawrence M. Levy, Secretary
Waltham, Massachusetts
January 9, 1998
                                
                            IMPORTANT
                                
 WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE SIGN  AND
 RETURN  THE ENCLOSED PROXY CARD AS PROMPTLY AS POSSIBLE IN  THE
 ENCLOSED POSTAGE-PREPAID ENVELOPE.  IF A QUORUM IS NOT REACHED,
 THE  COMPANY  WILL  HAVE THE ADDED EXPENSE OF RE-ISSUING  THESE
 PROXY  MATERIALS.  EVEN IF YOU HAVE GIVEN YOUR PROXY, THE PROXY
 MAY BE REVOKED AT ANY TIME PRIOR TO EXERCISE BY FILING WITH THE
 SECRETARY  OF THE COMPANY A WRITTEN REVOCATION, BY EXECUTING  A
 PROXY  WITH  A  LATER DATE, OR BY ATTENDING AND VOTING  AT  THE
 MEETING.
                                
                 THANK YOU FOR ACTING PROMPTLY.
                                
 
 
                          HOLOGIC, INC.
                         ______________
                                
                         PROXY STATEMENT
                                
               1998 ANNUAL MEETING OF STOCKHOLDERS
                        FEBRUARY 24, 1998
                                
         INFORMATION CONCERNING SOLICITATION AND VOTING

General

      The  enclosed proxy is solicited on behalf of the Board  of
Directors of Hologic, Inc. (the "Company"), for use at the Annual
Meeting of Stockholders to be held on Tuesday, February 24, 1998,
at  10:00  a.m.,  local time (the "Annual Meeting"),  or  at  any
continuation or adjournment thereof, for the purposes  set  forth
herein  and  in  the  accompanying Notice of  Annual  Meeting  of
Stockholders.  The Annual Meeting will be held at the offices  of
the  Company,  590 Lincoln Street, Waltham, Massachusetts  02154.
This  proxy statement, the accompanying proxy card and the annual
report to stockholders are first being mailed to stockholders  on
or about January 9, 1998.

Record Date and Stock Ownership

      Only  stockholders of record at the close  of  business  on
January 5, 1998, are entitled to receive notice of and to vote at
the  Annual Meeting.  At the close of business on January 5, 1998
there were outstanding and entitled to vote 13,143,183 shares  of
common  stock  of the Company, par value $.01 per share  ("Common
Stock").  Each stockholder is entitled to one vote for each share
of Common Stock.

Revocability of Proxies

      Any  person  giving a proxy in the form  accompanying  this
statement  has the power to revoke it at any time  before  it  is
voted.   It  may be revoked by filing with the Secretary  of  the
Company  at the Company's principal executive office, 590 Lincoln
Street,   Waltham,   Massachusetts  02154,  written   notice   of
revocation or a duly executed proxy bearing a later date,  or  it
may  be  revoked by attending the Annual Meeting  and  voting  in
person.

Voting and Solicitation

      The  affirmative vote of the holders of a plurality of  the
shares  of  Common Stock present or represented by proxy  at  the
Annual  Meeting  is required for the election of directors.   The
affirmative  vote  of a majority of the shares  of  Common  Stock
present or represented by proxy at the Annual Meeting is required
for the approval of each of the other matters to be voted upon at
the  Annual  Meeting.  A majority of the shares of  Common  Stock
outstanding is required to be present or represented by proxy  at
the Annual Meeting in order to constitute the quorum necessary to
take action at the Annual Meeting.

      Votes cast by proxy or in person at the Annual Meeting will
be  tabulated  by  the inspector of elections appointed  for  the
Annual Meeting.  The inspector of elections will treat broker non-
votes  and  abstentions  as  Common Stock  that  is  present  and
entitled  to vote for purposes of determining the presence  of  a
quorum  but as not voted for purposes of determining the approval
of any matter submitted to stockholders for a vote.  Abstentions,
including broker non-votes, will have no effect on the outcome of
the  vote  for  the election of directors or the ratification  of
auditors.

      All costs of this solicitation of proxies will be borne  by
the Company.  The Company has retained American Stock Transfer  &
Trust  Company  to  aid  in  the  solicitation  of  proxies  from
stockholders,  banks  and  other  institutional  nominees.    The
Company   may   reimburse  brokerage  firms  and  other   persons
representing  beneficial owners of shares  for  their  reasonable
expenses  incurred in forwarding solicitation materials  to  such
beneficial owners.  Original solicitation of proxies by mail  may
be supplemented by telephone, telegram, or personal solicitations
by   directors,  officers,  or  employees  of  the  Company.   No
additional compensation will be paid for any such services.

Deadline for Receipt of Stockholder Proposals

      Proposals of stockholders of the Company which are intended
to be presented by such stockholders at the Company's 1999 Annual
Meeting of Stockholders must be received by the Company no  later
than  September 10, 1998, in order to be considered for inclusion
in  the  proxy  statement  and form of  proxy  relating  to  that
meeting.
                                
                           PROPOSAL 1
                                
                      ELECTION OF DIRECTORS

      A  board  of  seven (7) directors is to be elected  at  the
Annual  Meeting. Unless otherwise instructed, the  proxy  holders
will  vote  the  proxies  received  by  them  for  the  Board  of
Directors' nominees named below.  All nominees, except  Steve  L.
Nakashige,  are currently directors of the Company.  In the event
that any nominee is unable or declines to serve as a director  at
the time of the Annual Meeting, the proxies will be voted for the
nominee, if any, who shall be designated by the present Board  of
Directors  to  fill  the vacancy.  It is not  expected  that  any
nominee will be unable or will decline to serve as director.  The
proposed  nominees  are  not  being  nominated  pursuant  to  any
arrangement or understanding with any person. The term of  office
of each person elected as a director will continue until the next
Annual  Meeting  of  Stockholders or until a successor  has  been
elected and qualified.

       Set   forth  below  is  certain  biographical  information
regarding the nominees, including information furnished  by  them
as  to  their principal occupation for the last five  (5)  years,
certain  other directorships held by them and their  ages  as  of
January 5, 1998.
<TABLE>
<CAPTION>
                                                                     Director
     Name               Age            Position                       Since
     ----               ---            --------                      --------
<S>                     <C>       <C>                                <C>    
S. David Ellenbogen     59      Chairman of the Board and
                                    Chief Executive Officer          1985
Steve L. Nakashige      48      President and
                                    Chief Operating Officer        nominated
Jay A. Stein            55      Senior Vice President, Chief
                                    Technical Officer and
                                    Director                         1985
Irwin Jacobs            60      Director                             1990
William A. Peck         64      Director                             1990
Gerald Segel            76      Director                             1990
Elaine  Ullian          50      Director                             1996
</TABLE>

      Mr. Ellenbogen, a co-founder of the Company, has served  as
its Chief Executive Officer and a director since its organization
in  October 1985, as its Chairman of the Board of Directors since
May  1994,  as its President from October 1985 until May 1994 and
as its Treasurer from October 1985 until February 1992.  Prior to
founding   the  Company,  Mr.  Ellenbogen  served  as  President,
Treasurer and a director of Diagnostic Technology, Inc.  ("DTI"),
which  he co-founded with Dr. Stein in 1981. DTI, which developed
an x-ray product for digital angiography, was acquired in 1982 by
Advanced  Technology Laboratories, Inc. ("ATL"),  a  wholly-owned
subsidiary of Squibb Corporation.  Mr. Ellenbogen was involved in
the  management of the digital angiography group of ATL from 1982
to  1985.   Since  July 1989, Mr. Ellenbogen has  also  been  the
President,  and a director of Vivid Technologies, Inc.  ("Vivid")
and  typically devotes approximately sixteen hours  per  week  to
Vivid pursuant to a management agreement between the Company  and
Vivid.  See "Certain Transactions".

      Mr.  Nakashige has served as President and Chief  Operating
Officer  of the Company since May 1994.  From 1988 to  1994,  Mr.
Nakashige was with General Electric Medical Systems where he held
the position of Senior Manager, Ultrasound Business from 1990  to
1994  and Manager, Ultrasound Marketing Operations from  1988  to
1990.   From  1986 to 1988, Mr. Nakashige was Vice  President  of
Operations of Biosound Inc., a medical equipment manufacturer.

      Dr.  Stein, a co-founder of the Company, has served as  its
Senior  Vice  President, Chief Technical Officer and  a  director
since  its  organization.   Dr. Stein  co-founded  DTI  with  Mr.
Ellenbogen  in  1981,  served  as Vice  President  and  Technical
Director  of  DTI  and  was  Technical Director  of  the  digital
angiography group of its successor, ATL, from 1982 to 1985.   Dr.
Stein   received  a  Ph.D.  in  Physics  from  The  Massachusetts
Institute  of Technology.  He is the principal author of  fifteen
patents  involving x-ray technology.  Since July 1989, Dr.  Stein
has also been the Senior Vice President, Technical Director and a
director of Vivid and has been devoting approximately eight hours
per  week to Vivid pursuant to a management agreement between the
Company and Vivid.  See "Certain Transactions".

      Mr. Jacobs has been a director of the Company since January
1990.   Mr.  Jacobs,  currently retired,  was  the  President  of
Dataviews,  Inc.,  a company which manufactures  and  distributes
software  products, from January 1992 to September  1997.   Since
December 1990, Mr. Jacobs has also been the Chairman of the Board
of   Personal  Protection  Consultants,  Inc.,  a  company  which
provides  specialized training to hospitals and  law  enforcement
agencies.   From May 1990 to December 1990, Mr. Jacobs was a Vice
President  of  Ask Computers, Inc., a computer system  developer.
From  1987 to May 1990, Mr. Jacobs was the President and Chairman
of  the  Board  of  Directors of Perception Technology  Corp.,  a
manufacturer of voice response systems.

      Dr.  Peck has been a director of the Company since  January
1990.   In 1989, Dr. Peck became the Vice Chancellor for  Medical
Affairs at Washington University (Executive Vice Chancellor since
1993) and Dean of the Washington University School of Medicine in
St.  Louis,  Missouri.  From 1976 until his appointment  as  Vice
Chancellor,  Dr.  Peck was a Professor of Medicine  and  the  Co-
Chairman  of the Department of Medicine at Washington University,
and  the Physician-in-Chief at the Jewish Hospital of St.  Louis.
Dr.  Peck  is  a member of the Board of Trustees of the  National
Osteoporosis Foundation and served as its President from 1985  to
1990.   Dr.  Peck also serves as a director of Allied  Healthcare
Products,  Inc.,  Angelica  Corporation,  Reinsurance  Group   of
America, Inc. and Boatman's Trust Company.

      Mr.  Segel  has been a director of the Company since  March
1990.  Mr. Segel, currently retired, was Chairman of the Board of
Tucker Anthony Incorporated from January 1987 to May 1990.   From
1983  through  January  1987 he served  as  President  of  Tucker
Anthony  Incorporated.  Mr. Segel also serves as  a  director  of
Litchfield  Financial,  Inc.,  Vivid  and  Boston  Communications
Group, Inc.

     Ms. Ullian has been a director of the Company since February
1996.   In  1996,  Ms. Ullian was appointed President  and  Chief
Executive   Officer  of  Boston  Medical  Center,  the  successor
corporation  of  Boston University Medical Center  Hospital.   In
April   1994,  Ms.  Ullian  was  appointed  President  and  Chief
Executive  Officer of Boston University Medical Center  Hospital.
From January 1987 to March 1994, Ms. Ullian held the position  of
President    and    Chief   Executive   Officer    of    Faulkner
Corporation/Faulkner Hospital. From 1984 to 1987,  she  was  Vice
President for Clinical Operations at New England Medical  Center.
Ms.  Ullian  is currently a member of the Governor's  Council  on
Economic Growth and Technology.

Board of Directors' Meetings and Committees

      The  Board of Directors met six times during the year ended
September 27, 1997.  Each director attended at least 75%  of  the
meetings of the Board of Directors and each of its Committees  on
which they served.

      Standing  committees  of  the Board  include  an  Executive
Committee, an Audit Committee and a Compensation Committee.   The
Board  does  not  have  a  nominating committee  or  a  committee
performing a similar function.

      Messrs.  Ellenbogen, Jacobs and Segel  and  Dr.  Stein  are
currently  the members of the Executive Committee.  The Executive
committee did not meet formally during fiscal 1997. The Executive
Committee  has  all  the powers and authority  of  the  Board  of
Directors, except those powers that may not lawfully be delegated
by  the  Board  of  Directors and except  those  specific  powers
delegated  by  the  Board  of Directors to  any  other  committee
appointed by it.

      Messrs. Jacobs and Segel are currently the members  of  the
Audit  Committee.   During fiscal 1997, the Audit  Committee  met
twice   with  the  Company's  independent  auditors.   The  Audit
Committee  reviews  with the Company's independent  auditors  the
scope  of  the audit for the year, the results of the audit  when
completed, the adequacy of the Company's internal control systems
and  financial reporting procedures and the independent auditors'
fee for services performed.

      Messrs.  Jacobs  and Segel, Dr. Peck  and  Ms.  Ullian  are
currently  the  members of the Company's Compensation  Committee.
During  fiscal 1997, the Compensation Committee met  twice.   The
Compensation Committee determines the compensation to be paid  to
key  officers of the Company and administers the Company's  Stock
Incentive  Plans,  Executive  and  Key  Employee  Bonus  Program,
Performance-Bonus  Plan, 1995 Employee Stock Purchase  Plan,  and
401(k) Plan.

Compensation of Directors

      In fiscal 1997, each non-employee director received (i)  an
annual  retainer of $12,000, payable $3,000 per quarter,  (ii)  a
director's meeting fee of $1,500 for each meeting of the Board of
Directors at which the director was physically present  and  $600
for  each meeting at which the director participated by telephone
and (iii) a committee meeting fee for each meeting of a committee
of  the  Board of Directors at which the director was  physically
present, in the amount of $1,200 if the meeting was held on a day
other  than the day of the meeting of the Board of Directors  and
$600  if  held  on the same day as the meeting of  the  Board  of
Directors,  but no fee if the committee meeting was held  at  the
same  time or immediately in conjunction with the meeting of  the
Board of Directors.

      Non-employee  directors are also eligible to receive  stock
options pursuant to the Company's Amended and Restated 1990  Non-
Employee Director Stock Option Plan (the "Director's Plan").  The
Director's Plan provides that each eligible director will receive
an  option to purchase 10,000 shares of Common Stock at the  time
the  director is first elected to the Board of Directors.   These
options become exercisable in increments of 2,000 shares  over  a
five  year  period  for  each  year  that  the  director  remains
affiliated with the Company.  Each director who has served  as  a
director  for  a full fiscal year will be granted  an  option  to
purchase  an additional 8,000 shares of Common Stock on  December
15  of  each year, provided he or she continues to be an eligible
director,  until  the director has received options  to  purchase
44,000  additional shares.  These options become  exercisable  in
full  six months after the date of grant.     The exercise  price
for  all  options granted under the Director's Plan is  the  fair
market  value  of  the Common Stock at the  time  the  option  is
granted.   The  exercise price may be paid in cash,  with  Common
Stock  (valued at fair market value on the date of purchase),  or
by a combination of cash and Common Stock.  On December 15, 1996,
options  to purchase 8,000 shares of Common Stock, at an exercise
price of $24.00 per share, were granted to each of Messrs. Jacobs
and Segel and Dr. Peck and Ms. Ullian under the Director's Plan.
                                
                                
                                
                                
                           PROPOSAL 2
                                
                                
  RATIFICATION OF APPOINTMENT OF INDEPENDENT PUBLIC ACCOUNTANTS

      The  Board  of  Directors recommends that the  stockholders
ratify the selection of Arthur Andersen LLP as independent public
accountants  to examine the consolidated financial statements  of
the  Company  and  its subsidiaries for the  fiscal  year  ending
September  26,  1998.   Arthur  Andersen  LLP  has  audited   the
Company's financial statements annually since 1986, and the Board
of  Directors believes it is desirable and in the best  interests
of  the  Company  to  continue  employment  of  that  firm.   The
affirmative  vote  of  a majority of the Company's  Common  Stock
present  in person or represented by proxy is required to  ratify
the   appointment  of  Arthur  Andersen  LLP  as  the   Company's
independent  public accountants.  Action by stockholders  is  not
required  by  law  in  the  appointment  of  independent   public
accountants, but their appointment is submitted by the  Board  of
Directors  in  order  to give the stockholders  a  voice  in  the
designation  of accountants.  If the appointment is not  ratified
by  the stockholders, the Board of Directors will reconsider  its
choice of Arthur Andersen LLP as the Company's independent public
accountants.

      A representative of Arthur Andersen LLP will be present at
the  meeting to make a statement if such representative  desires
to do so and to respond to appropriate questions.
                                
                                
                                
                        OTHER INFORMATION
                                                                 
            SHARE OWNERSHIP OF DIRECTORS, OFFICERS
                 AND CERTAIN BENEFICIAL OWNERS

      The  following table sets forth certain information  as  of
January 5, 1998 with respect to the beneficial ownership  of  the
Company's  Common  Stock  of  each  director,  each  nominee  for
director,   each   named  executive  officer   in   the   Summary
Compensation  Table  under "Executive Compensation",  below,  all
executive  officers  and directors as a group,  and  each  person
known by the Company to be the beneficial owner of 5% or more  of
the  Company's  Common  Stock.  This information  is  based  upon
information received from or on behalf of the named individuals.
<TABLE>
<CAPTION>

                                        Beneficial Ownership (1)
          Name of                        Number        Percent of
      Beneficial Owner                  of  Shares    Common Shares
      ----------------                  ----------    --------------
<S>                                      <C>             <C>
S. David Ellenbogen (2)                   537,169        4.1%
Jay A. Stein (3)                          386,309        2.9%
Steve L. Nakashige (4)                    138,810        1.1%
Jean Chaintreuil (4)                       16,332         *
Mark A. Duerst (4)                         86,228         *
Glenn P. Muir (4)                          79,158         *
Irwin Jacobs (4)                           32,000         *
William A. Peck (4)                        14,000         *
Gerald Segel (4)                           28,000         *
Elaine Ullian (4)                          12,000         *

All directors and executive
 officers as a group(11 persons)(4)     1,528,053       11.6%
</TABLE>
_____________________

*    Less than one percent.

(1)   Unless  otherwise  noted, each person identified  possesses
sole voting and investment power with respect to the shares listed.

(2)   Includes  (i) 48,110 shares held by, or in trust  for,  Mr.
Ellenbogen's  children and grandchildren and  (ii)  7,150  shares
held  by  Mr.  Ellenbogen as trustee, all  of  which  shares  Mr.
Ellenbogen disclaims beneficial ownership. Also includes  options
to  purchase 110,996 shares of Common Stock which are exercisable
within 60 days after January 5, 1998.

(3)   Includes  (i) 7,230 shares held by, or in  trust,  for  Dr.
Stein's  children  and (ii) 23,170 shares held by  Dr.  Stein  as
trustee  or  custodian, all of which shares Dr.  Stein  disclaims
beneficial ownership.  Also includes options to purchase  110,996
shares of Common Stock which are exercisable within 60 days after
January 5, 1998.

(4)   Includes the following shares subject to options which  are
exercisable within 60 days after January 5, 1998: Mr. Nakashige -
138,332; Mr. Chaintreuil - 16,332; Mr. Duerst - 85,164; Mr.  Muir
- -  77,332;  Mr. Jacobs - 32,000; Dr. Peck - 14,000; Mr.  Segel  -
28,000;  Ms.  Ullian - 12,000; and all executive  officers  as  a
group - 753,484.




                       EXECUTIVE OFFICERS
                                
      The names of the executive officers of the Company who  are
not   directors   of   the  Company,  and  certain   biographical
information furnished by them, are set forth below:
<TABLE>
<CAPTION>
     Name                     Age                 Title
     ----                     ---                 -----
<S>                            <C>                  <C>
Jean  Chaintreuil              42             Vice President of
                                                European Operations
Mark  A.  Duerst               41             Vice President of
                                                Sales and Marketing
Glenn  P.  Muir                38             Vice President of
                                                Finance and Treasurer
Joel  B.  Weinstein            47             Vice President of
                                                Business Development
</TABLE>

     Executive officers are chosen by and serve at the discretion
of the Board of Directors of the Company.

      Mr.  Chaintreuil has served as Vice President  of  European
Operations  of the Company since February 1993.  Mr.  Chaintreuil
has  held the position of President, Hologic Europe since joining
the  Company in October 1991.  From 1986 to 1991, Mr. Chaintreuil
held   a  variety  of  positions  with  General  Electric/C.G.R.,
including  International Marketing Manager  for  mammography  and
stand-alone  products and Regional Sales and Service Manager  for
the Paris and west France territory.

      Mr.  Duerst   has  served as Vice President  of  Sales  and
Marketing  since September 1994.  Prior to that, Mr. Duerst  held
the  position of Director of North American Sales since 1990  and
the  position of Central Regional Sales Manager since joining the
Company  in  1989.   From  1988  to  1989,  Mr.  Duerst  was   an
independent marketing and sales consultant and from 1983 to  1987
he was Director of Sales and Marketing of Lunar Corporation.

      Mr. Muir, a Certified Public Accountant, has served as Vice
President of Finance and Treasurer of the Company since  February
1992.   Prior  to that, Mr. Muir held the position of  Controller
since  joining the Company in October 1988.  From 1986  to  1988,
Mr.  Muir  was  Vice President of Finance and Administration  and
Chief Financial Officer of Metallon Engineered Materials Corp., a
manufacturer  of composite materials.  Mr. Muir received  an  MBA
from  the  Harvard Graduate School of Business Administration  in
1986.

      Mr.  Weinstein  has  served as Vice President  of  Business
Development since August 1993.  Prior to that, Mr. Weinstein held
the  position  of Vice President of Marketing since  joining  the
Company in 1987.  From 1980 to 1987, Mr. Weinstein held a variety
of   positions  with  Advanced  Technology  Laboratories,   Inc.,
including  Marketing  Director  from  1982  to  1984   and   Vice
President, Business Development from 1984 to 1987.

                                 
                                
                                
                             
               COMPENSATION OF EXECUTIVE OFFICERS

Summary Compensation Table

      The  following table sets forth information concerning  the
compensation during the last three fiscal years of the  Company's
Chief   Executive  Officer  and  the  four  other   most   highly
compensated  executive  officers whose annual  salary  and  bonus
exceeded  $100,000 for services in all capacities to the  Company
during the last fiscal year (the "named executive officers").
<TABLE>
<CAPTION>
 
                                                             Long-Term
                                                            Compensation
Name and                Fiscal     Annual Compensation   Securities Underlying        All Other
Principal Position       Year      Salary ($) Bonus ($)       Options  (#)       Compensation ($)(1)
- ------------------      -----      ------     --------    --------------------   --------------------
<S>                       <C>       <C>        <C>               <C>                  <C>
S. David Ellenbogen       1997     $201,382   $150,000          25,000               $3,325         
Chairman and CEO          1996     $179,822   $180,000            ---                $3,325
                          1995     $167,775   $ 42,500         130,000               $2,310    

Steve L. Nakashige        1997     $152,441   $ 75,000          20,000               $3,325
President and COO         1996     $153,283   $100,000            ---                $3,325  
                          1995     $133,909   $ 40,000          80,000               $3,954 

Jean Chaintreuil          1997     $242,031   $ 15,000          15,000                 ---   
Vice President            1996     $227,671   $ 20,000            ---                  --- 
European Operations       1995     $218,406   $  5,000            ---                  ---

Mark A. Duerst            1997     $197,909   $ 35,000          15,000               $3,325
Vice President            1996     $199,252   $ 20,000            ---                $3,223
Sales and Marketing       1995     $169,592   $  5,000          40,000               $2,310

Glenn P. Muir             1997     $145,104   $ 75,000          20,000               $3,541
Vice President            1996     $143,784   $100,000            ---                $4,019
Finance                   1995     $116,817   $ 45,000          90,000               $2,159
__________________
</TABLE>
(1)  The amounts reported in this column consist of the Company's
matching contribution under its 401(k) Profit-Sharing Plan.



Stock Option Grants in Last Fiscal Year

      The  following table sets forth the stock options granted  to
the Company's named executive officers during the fiscal year ended
September 27, 1997.
<TABLE>
<CAPTION>
                                                                               Potential Realizable Value
                       Individual Grants                                       at Assumed Annual Rates
                  Number of        % of Total                                  of Stock Price Appreciation
                  Securities     Options Granted     Exercise                  for Option Term  (3)       
             Underlying Options    to Employees       Price    Expiration      ---------------------------
Name             Granted (1)      in Fiscal Year  ($/share)(2)     Date        5% ($)        10% ($)        
- ---          ------------------   --------------   -----------  ---------      ------        -------   
<S>                   <C>              <C>           <C>            <C>           <C>           <C>    
S.D. Ellenbogen      25,000             9%           $19.25       5/5/07       $302,656       $766,989  

S. Nakashige         20,000             7%           $19.25       5/5/07       $242,124       $613,591

J. Chaintreuil       15,000             5%           $19.25       5/5/07       $181,593       $460,193

M. Duerst            15,000             5%           $19.25       5/5/07       $181,593       $460,193

G. Muir              20,000             7%           $19.25       5/5/07       $242,124       $613,591
_____________
</TABLE>
(1)  Options vest at the rate of 20% per year, beginning on May  5,
1998.   Th options were granted under the Company's 1995
Combination Stock Option Plan.

(2)   The exercise price is equal to the fair market value of the
stock on the date of grant.

(3)   The 5% and 10% assumed rates of annual compounded stock price
appreciation are mandated by the rules of the SEC and do not
represent the Company's estimate or projection of future Common
Stock prices.

Aggregated Option Exercises in Last Fiscal Year and Fiscal Year
    End Option Values

      The  following table sets forth certain information regarding
the exercise of stock options during the fiscal year ended
September 27, 1997 and the fiscal year-end value of unexercised
options for the Company's named executive officers.
<TABLE>
<CAPTION>
   
    
                                                           Number of
                                                     Securities Underlying            Value of Unexercised
                                                      Unexercised Options            In-the-Money Options at
                   Shares Acquired      Value        at FiscalYear End (#)            Fiscal Year End ($)(2)     
Name               on Exercise (#)  Realized ($)(1)  Exercisable /Unexercisable     Exercisable/Unexercisable
- ----               ---------------  ---------------  --------------------------     --------------------------
<S>                 <C>               <C>                 <C>        <C>            <C>              <C>          
S. D. Ellenbogen      ---               ---              57,998  /  90,002         $1,109,528  /  $1,362,847   
S. Nakashige         50,000           $1,001,563         71,666  /  93,334         $1,473,322  /  $1,584,178
J. Chaintreuil        4,000           $   94,625          7,666  /  25,334         $   94,867  /  $  245,258
M. Duerst             ---               ---              47,032  /  60,468         $  942,631  /  $1,012,332
G. Muir               ---               ---              39,666  /  66,334         $  757,134  /  $  991,866
___________________
</TABLE>
(1)    The amount "realized" reflects the appreciation on the date
of exercise (based on the excess of the fair market value of the
shares on the date of exercise over the exercise price).  However,
because the executive officers may keep the shares they  acquired
upon the exercise  of the options (or sell them  at  a  different
price), these amounts do not necessarily reflect cash realized upon
the sale of those shares.

(2)      Based upon the $25.625 closing  market  price of the
Company's Common Stock as reported on the Nasdaq National Market
System on September 27, 1997 minus the respective option exercise
price.


Executive Bonus Program

      The  Compensation  Committee  of  the  Board  of  Directors
approved  an Executive and Key Employee Bonus Program for  fiscal
1998  under which executive officers, senior management  and  key
contributors  selected  by  the  Compensation  Committee  may  be
eligible  for  cash  bonuses, awarded at the  discretion  of  the
Compensation Committee, to be paid in the first quarter of fiscal
1999.  Under this program, if pre-tax profits exceed $15,000,000,
a  bonus pool is expected to be created equal to up to 5% of  the
Company's  pre-tax  profits.  No bonus pool  is  expected  to  be
created   if   the  Company's  pre-tax  profits  do  not   exceed
$15,000,000.   For fiscal 1997, bonuses of $725,000 were  granted
under a similar program approved for that year.

Compensation Committee Interlocks and Insider Participation

      Decisions regarding executive compensation are made by  the
Company's Compensation Committee of the Board of Directors, which
is  composed of Irwin Jacobs, William A. Peck, Gerald  Segel  and
Elaine  Ullian.  The Compensation Committee also administers  the
Company's Stock Incentive Plans, Executive and Key Employee Bonus
Program, Performance - Bonus Plan, and 401(k) Plan.  None of  the
members of the Compensation Committee has ever been an officer or
employee  of  the Company or any of its subsidiaries.   Glenn  P.
Muir, the Vice President of Finance and Treasurer of the Company,
serves  on  the Board of Directors and the Compensation Committee
of  Vivid.   S. David Ellenbogen, the Chairman of the  Board  and
Chief  Executive Officer of the Company, and Jay  A.  Stein,  the
Senior Vice President, Chief Technical Officer and a director  of
the  Company,  are  executive officers of  Vivid.   See  "Certain
Transactions".
                                
                                
                                
 REPORT OF THE COMPENSATION COMMITTEE ON EXECUTIVE COMPENSATION

      The  Compensation  Committee of  the  Board  of  Directors,
consisting  entirely  of   independent non-management  directors,
approves all policies under which compensation is paid or awarded
to  the Company's executive officers.  The Committee is comprised
of Messrs. Jacobs, Peck and Segel and Ms. Ullian.

Hologic's Compensation Philosophy and Plan

      The Company's executive compensation program is designed to
attract   and  retain  superior  executive  talent,  to   provide
incentives  and rewards to executive officers who will contribute
to  the  long-term  success of Hologic and to closely  align  the
interests of executives with those of Hologic's stockholders.

      The  Committee reviews the Company's executive compensation
program  through  the  application  of  the  subjective  business
judgment of each of its members and through an informal survey of
executive   compensation  programs  of   peer   companies.    The
Compensation Committee does not use a quantitative method or  use
a  mathematical formula to set any element of compensation for  a
particular  executive officer.  The Compensation  Committee  uses
discretion   and   considers  all  elements  of  an   executive's
compensation  package when setting each portion  of  compensation
which   is   based  upon  corporate  performance  and  individual
initiatives  and  performance.  The  principle  elements  of  the
Company's  executive compensation program consist  of:  (i)  base
annual  salary,  (ii)  executive bonus program  and  (iii)  stock
options.

Base   Annual  Salaries.   Base  annual  salaries  for  executive
officers    are   initially   determined   by   evaluating    the
responsibilities of the position and the experience and knowledge
of   the  individual.   Also  taken  into  consideration  is  the
competitiveness   of  the  marketplace  for   executive   talent,
including  a  comparison of base annual salaries  for  comparable
positions at peer companies.  Individual adjustments are made  at
the   discretion  of  the  Compensation  Committee,  taking  into
consideration factors such as the Company's  performance and  the
Compensation   Committee's   subjective   perception    of    the
individual's performance.

Executive  Bonus  Program.   The Company maintains  an  Executive
Bonus  Program which provides for a bonus pool to be  established
for executive officers, senior management and key contributors of
the  Company based upon the amount by which the Company's pre-tax
profits  exceed  certain specified targets  for  a  fiscal  year.
Bonuses from this pool are allocated among the executive officers
and   other   eligible  employees  at  the  discretion   of   the
Compensation  Committee, based upon the Compensation  Committee's
subjective determination of the participant's performance  during
the  year.   For  Fiscal 1997, bonuses aggregating $725,000  were
granted  under the Executive Bonus Program. The 1997 program  was
based  upon pre-tax profits exceeding $15,000,000, with up to  5%
of  the  pre-tax profits available to fund the bonus pool.    See
"Compensation  of  Executive  Officers  --  Summary  Compensation
Table" and "-- Executive Bonus Program".

Stock   Options.  The  third  component  of  executive  officers'
compensation  is  the Company's 1986 and 1995  Combination  Stock
Option  Plans pursuant to which the Company has granted  to  non-
director executive officers options to purchase shares of  Common
Stock.

      Stock  options are designed to align the interests  of  the
executive  with  those of the stockholders.   Stock  options  are
granted  at an exercise price equal to the fair market  value  of
the  Common Stock on the date of grant.  These options  generally
vest  at  the  rate  of  20%  or 25% per  year,  with  the  first
installment  vesting  either at the end  of  one  or  two  years,
respectively,  from the date of employment (for  options  granted
upon initial employment) or the date of grant and are exercisable
within  ten years from the date of grant.  This plan is  designed
to provide incentives for the creation of long-term value for the
Company's  stockholders as the full benefit of  the  compensation
package cannot be realized unless stock price appreciation occurs
over a number of years.  The size of individual stock grants  are
based   upon  the  Committee's  subjective  review  of  the   job
responsibility  and  individual  contribution  to  the  Company's
success.  Previous stock option grants are considered when awards
are determined.

Compensation of the Chief Executive Officer

      In January 1997, Mr. Ellenbogen's base salary was increased
to  $200,000 from $180,000, which the Committee considers  to  be
comparable  to the salaries of chief executive officers  of  peer
companies  based on the Committee's informal survey of  executive
compensation  at peer companies.  In fiscal 1997, Mr.  Ellenbogen
also  received  a  bonus of $150,000.  The bonus represented  the
amount  of  the  fiscal  1997  bonus  pool  under  the  Company's
Executive  Bonus  Program  allocated to  Mr.  Ellenbogen  by  the
Compensation    Committee.    This   allocation   reflects    the
Compensation   Committee's   subjective   judgment    that    Mr.
Ellenbogen's  efforts contributed significantly to the  Company's
success  during fiscal 1997.  In fiscal 1997, Mr. Ellenbogen  was
instrumental in, among other things, the Company achieving record
sales and operating results.

Conclusion

      Through  these  programs,  a  significant  portion  of  the
Company's executive compensation is linked directly to individual
and  Company performance in pursuance of strategic goals as  well
as  stock price appreciation.  The Compensation Committee intends
to  continue  the  policy  of linking executive  compensation  to
Company  performance and stockholder return, recognizing however,
that  fluctuations in the operating results of the  business  may
result over time.

          The Compensation Committee

          Irwin Jacobs
          William A. Peck
          Gerald Segel
          Elaine Ullian



                        PERFORMANCE GRAPH

       The   following  Performance  Graph  compares  the  yearly
percentage  change in the Company's cumulative total  shareholder
return  on  the  Company's  Common  Stock  for  the  period  from
September  30,  1992 through September 27, 1997, based  upon  the
market  price of the Company's Common Stock, with the  cumulative
total return on the Standard and Poor's 500 Stock Index (the "S&P
500")  and the Standard and Poor's Medical Products and  Supplies
Index  (the  "S&P  Medical  Products")  for  that  period.    The
Performance Graph assumes the investment of $100 on September 30,
1992  in  the  Company's Common Stock, the S&P 500  and  the  S&P
Medical Products, and the reinvestment of any and all dividends.












<TABLE>
<CAPTION>

                                    Cumulative Total Return

               September   September   September  September  September  September
                 1992        1993        1994       1995       1996       1997
               ---------   ---------   ---------  ---------   --------   --------
<S>               <C>         <C>        <C>         <C>        <C>        <C>
Hologic,Inc.     $100        $ 67        $231       $378       $890       $837
S&P 500          $100        $113        $117       $152       $183       $257
S&P Medical
  Products       $100        $ 76        $ 97       $157       $188       $233

</TABLE>
                                
                          
                                      
                      CERTAIN TRANSACTIONS
                                
     For the fiscal year ended September 27, 1997, the following
transactions  occurred which involved more than $60,000  between
the  Company  and any director, executive officer, five  percent
(5%)  beneficial  owner of the Company's  Common  Stock  or  any
member of the immediate family of any of the foregoing persons.

Vivid Technologies, Inc.

      In  June  1989, the Company granted an exclusive perpetual
license  to  use certain patent rights and technology  to  Vivid
Technologies, Inc. for the development, manufacture and sale  of
X-ray screening security systems for explosives, drugs, currency
and other contraband (subject to termination by either party for
certain  defaults).  In September 1996, this license was amended
to  grant Vivid a nonexclusive license to use these patents  and
technology for the development, manufacture and sale  of  X-ray-
based  products  capable  of  being  used  for  process  control
applications   in   the  food  and  beverage  industries.    Mr.
Ellenbogen and Dr. Stein are directors of Vivid and hold similar
offices in Vivid as they do in the Company.  Mr. Ellenbogen  and
Dr. Stein collectively beneficially own approximately 12% of the
outstanding voting stock of Vivid.

      Under the license agreement, Vivid is required to pay  the
Company  royalties of 5% of the first  $50 million of net  sales
of  screening  security systems using the Company's  technology,
and 3% of net sales in excess of $50 million, up to a maximum of
$200  million  of net sales of these products.   Vivid  is  also
required to pay royalties of 3% up to a maximum of $200  million
of net sales of products covered by the nonexclusive license for
food  and  beverage  process  control.   The  maximum  aggregate
royalties  payable by Vivid to the Company under this  exclusive
arrangement   are   $7  million,  and  under  the   nonexclusive
arrangement,  are $6 million.  In fiscal 1997,  Vivid  paid  the
Company  royalties of approximately $950,000 under  the  license
agreement,   on   aggregate  sales  through   fiscal   1997   of
approximately $77 million.

      Under  a management agreement, the Company provided  Vivid
with the part-time management services of Mr. Ellenbogen and Dr.
Stein.  Under this arrangement, Vivid was required  to  pay  the
Company its proportionate share of the Company's salary  of  the
employees rendering services to Vivid.  Currently, the  payments
made  under this arrangement are Vivid's proportionate share  of
Mr.  Ellenbogen's  and  Dr.  Stein's compensation.   Under  this
arrangement,  no compensation is paid by Vivid  to  any  of  the
Company's employees.  The management agreement may be terminated
by  either party on six month's written notice.  For the  fiscal
year  ended  September 27, 1997, Vivid was charged approximately
$130,000  by  the  Company  for  services  rendered  under   the
agreement.  In December 1997, Vivid paid the Company  a  $76,000
bonus for the management services provided in fiscal 1997.   The
Company  estimates  that  Mr.  Ellenbogen  and  Dr.  Stein  have
typically  devoted  approximately sixteen and  eight  hours  per
week, respectively, on matters involving Vivid.


                    SECTION 16(a) BENEFICIAL
                 OWNERSHIP REPORTING COMPLIANCE
                                
      Under  the  securities  laws of  the  United  States,  the
Company's  directors, its executive officers,  and  any  persons
holding more than ten percent of the Company's Common Stock  are
required  to  report their initial ownership  of  the  Company's
Common Stock and any subsequent changes in that ownership to the
Securities  and  Exchange Commission ("SEC").   Specific  filing
deadlines of these reports have been established and the Company
is  required to disclose in this Proxy Statement  any failure to
file  by these dates during the fiscal year ended September  27,
1997.   To  the  best of the Company's knowledge, all  of  these
filing  requirements  have  been  satisfied.   In  making   this
statement,   the   Company   has  relied   solely   on   written
representations of its directors and executive officers and  any
ten  percent  stockholders and copies of the reports  that  they
filed with the SEC.
                                
                          OTHER MATTERS

      The  Company knows of no other matters to be submitted  at
the  meeting.   If  any other matters properly come  before  the
meeting,  it  is  the  intention of the  persons  named  in  the
accompanying  proxy  to vote the shares represented  thereby  on
such matters in accordance with their best judgment.

Incorporation by Reference

     To the extent that this Proxy Statement has been or will be
specifically  incorporated by reference into any filing  by  the
Company  under  the Securities Act of 1933, as amended,  or  the
Securities Exchange Act of 1934, as amended, the sections of the
Proxy  Statement entitled "Report of the Compensation  Committee
on  Executive Compensation" and "Performance Graph" shall not be
deemed  to  be  so  incorporated, unless specifically  otherwise
provided in any such filing.
                                
             FINANCIAL MATTERS AND FORM 10-K REPORT

      The  Company's  annual report for the  fiscal  year  ended
September 27, 1997, is being mailed with this proxy statement to
stockholders   entitled  to  notice   of   the   meeting.    The
consolidated financial statements, unaudited selected  quarterly
data  and  management's  discussion and  analysis  of  financial
condition  and  results  of operations included  in  the  annual
report are incorporated by reference herein.

     THE  COMPANY  WILL  PROVIDE EACH BENEFICIAL  OWNER  OF  ITS
SECURITIES  WITH  A  COPY  OF AN ANNUAL  REPORT  ON  FORM  10-K,
INCLUDING  THE  FINANCIAL  STATEMENTS  AND  SCHEDULES   THERETO,
REQUIRED TO BE FILED WITH THE SECURITIES AND EXCHANGE COMMISSION
FOR  THE COMPANY'S MOST RECENT FISCAL YEAR, WITHOUT CHARGE, UPON
RECEIPT  OF  A  WRITTEN REQUEST FROM SUCH PERSON.  SUCH  REQUEST
SHOULD BE SENT TO INVESTOR RELATIONS, HOLOGIC, INC., 590 LINCOLN
STREET, WALTHAM, MASSACHUSETTS 02154.
                                                                 
                         VOTING PROXIES

      The  Board of Directors recommends an affirmative vote  on
all  proposals  specified.  Proxies will be voted as  specified.
If signed proxies are returned without specifying an affirmative
or negative vote on any proposal, the shares represented by such
proxies  will  be  voted  in favor of the  Board  of  Directors'
recommendations.

                              By order of the Board of Directors


                              Lawrence M. Levy, Secretary


Waltham, Massachusetts
January 9, 1998



           HOLOGIC, INC. PROXY FOR ANNUAL MEETING OF  STOCKHOLDERS
590 Lincoln Street        FEBRUARY 24, 1998
Waltham, MA  02154
(617) 890-2300

   The undersigned stockholder of HOLOGIC, INC., a Delaware corporation
(the  "Company"), acknowledges receipt of the Notice of Annual  Meeting
of Stockholders and Proxy Statement, dated  January 9, 1998, and hereby
appoints S. David Ellenbogen and Jay A. Stein, and each of them  acting
singly,  with  full  power of substitution, attorneys  and  proxies  to
represent the undersigned at the Annual Meeting of Stockholders of  the
Company  to be held at the offices of the Company, 590 Lincoln  Street,
Waltham,  Massachusetts 02154, on Tuesday, February 24, 1998, at  10:00
A.M.  local time, and at any adjournment or adjournments thereof,  with
all  power  which the undersigned would possess if personally  present,
and  to  vote all shares of stock which the undersigned may be entitled
to  vote  at said meeting upon the matters set forth in the  Notice  of
Meeting  in  accordance  with  the  following  instructions  and   with
discretionary authority upon such other matters as may come before  the
meeting.  All previous proxies are hereby revoked.

    1.  The  election of seven (7) directors nominated by the Board  of
        Directors for the ensuing year:
        
        FOR all nominees listed below            WITHHOLD AUTHORITY
        (except  as  indicated)        to vote for all nominees listed below

              ------------                        ---------------

       S. David Ellenbogen, Irwin Jacobs, Steve L. Nakashige,
       William A. Peck, Gerald Segel, Jay A. Stein, Elaine Ullian

    (INSTRUCTIONS:   To withhold authority to vote for any individual
    nominee, write that nominee's name on the space provided below.)
     _____________________________________________________________



     2.  To ratify the selection of Arthur Andersen LLP as the Company's
         independent public accountants:

             FOR_______      AGAINST_______     ABSTAIN______


This  proxy  is  solicited on behalf of the Board of  Directors.  This
proxy will be voted as specified or, where no direction is given, will
be voted for the proposals in Items 1& 2

PLEASE  SIGN,  DATE  AND MAIL THIS PROXY IMMEDIATELY  IN  THE  ENCLOSED
ENVELOPE.

Dated........................................, 1998
 .............................................
 .............................................

Please  sign your name exactly as it appears hereon.  When  signing  as
attorney,  executor,  administrator, trustee or guardian,  please  give
your  full title as it appears hereon.  When signing as joint  tenants,
all parties in the joint tenancy must sign.  When a proxy is given by a
corporation,  it  should  be signed  by an authorized officer  and  the
corporate seal affixed.




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