SAFECO CORP
SC 13G/A, 1998-09-10
FIRE, MARINE & CASUALTY INSURANCE
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<PAGE>


                              UNITED STATES
                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C. 20549

                                SCHEDULE 13G

                 Under the Securities Exchange Act of 1934
                          (Amendment No.    1  )*
                                         ------
                                

                       Dura Pharmaceuticals
- --------------------------------------------------------------------------------
                              (Name of Issuer)

                          Common Stock                
- --------------------------------------------------------------------------------
                       (Title of Class of Securities)

                                26632S109
                     ----------------------------------
                              (CUSIP Number)

                                 8/31/98
- --------------------------------------------------------------------------------
               (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this 
Schedule is filed:

     /X/ Rule 13d-1(b)

     / / Rule 13d-1(c)

     / / Rule 13d-1(d)


   *The remainder of this cover page shall be filled out for a reporting 
person's initial filing on this form with respect to the subject class of 
securities, and for any subsequent amendment containing information which 
would alter the disclosures provided in a prior cover page.

   The information required in the remainder of this cover page shall not 
be deemed to be "filed" for the purpose of Section 18 of the Securities 
Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that 
section of the Act but shall be subject to all other provisions of the Act 
(however, see the Notes).

                (Continued on following page(s))


<PAGE>

CUSIP No. 26632S109
          ---------

- -------------------------------------------------------------------------------
 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

     SAFECO Common Stock Trust
- -------------------------------------------------------------------------------
 (2) Check the Appropriate Box if a Member   (a)  / /
     of a Group (See Instructions)           (b)  / /
- -------------------------------------------------------------------------------
 (3) SEC Use Only

- -------------------------------------------------------------------------------
 (4) Citizenship or Place of Organization

     State of Delaware
- -------------------------------------------------------------------------------
 Number of Shares             (5) Sole Voting Power
 Beneficially                       0
 Owned by                    --------------------------------------------------
 Each Reporting               (6) Shared Voting Power
 Person With:                       2,873,700
                             --------------------------------------------------
                              (7) Sole Dispositive Power
                                    0
                             --------------------------------------------------
                              (8) Shared Dispositive Power
                                    2,873,700
- -------------------------------------------------------------------------------
 (9) Aggregate Amount Beneficially Owned by Each Reporting Person
                                    2,873,700
- -------------------------------------------------------------------------------
(10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See
     Instructions)        / /
- -------------------------------------------------------------------------------
(11) Percent of Class Represented by Amount in Row (9)
                                    6.198%
- -------------------------------------------------------------------------------
(12) Type of Reporting Person (See Instructions)
                                    IV
- -------------------------------------------------------------------------------

                                 Page 2 of 8


<PAGE>

CUSIP No. 26632S109
          ---------

- -------------------------------------------------------------------------------
 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

     SAFECO Asset Management Company
- -------------------------------------------------------------------------------
 (2) Check the Appropriate Box if a Member   (a)  / /
     of a Group (See Instructions)           (b)  / /
- -------------------------------------------------------------------------------
 (3) SEC Use Only

- -------------------------------------------------------------------------------
 (4) Citizenship or Place of Organization
     State of Washington
- -------------------------------------------------------------------------------
 Number of Shares             (5) Sole Voting Power
 Beneficially                       0
 Owned by                    --------------------------------------------------
 Each Reporting               (6) Shared Voting Power
 Person With:                       3,265,700
                             --------------------------------------------------
                              (7) Sole Dispositive Power
                                    0
                             --------------------------------------------------
                              (8) Shared Dispositive Power
                                    3,265,700
- -------------------------------------------------------------------------------
 (9) Aggregate Amount Beneficially Owned by Each Reporting Person
                                    3,265,700(1)
- -------------------------------------------------------------------------------
(10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See
     Instructions)        / /
- -------------------------------------------------------------------------------
(11) Percent of Class Represented by Amount in Row (9)
                                    7.043%
- -------------------------------------------------------------------------------
(12) Type of Reporting Person (See Instructions)
                                    IA
- -------------------------------------------------------------------------------

- -------------
(1)  The Reporting Person disclaims any beneficial ownership of the shares
     reported on this joint 13G. The reported shares are owned beneficially
     by registered investment ocmpanies for which the Reporting Person serves
     as an adviser, and include the shares reported in this joint 13G by
     SAFECO Common Stock Trust.

                                 Page 3 of 8


<PAGE>

CUSIP No. 26632S109
          ---------

- -------------------------------------------------------------------------------
 (1) Names of Reporting Persons.
     I.R.S. Identification Nos. of above persons (entities only).

     SAFECO Corporation
- -------------------------------------------------------------------------------
 (2) Check the Appropriate Box if a Member   (a)  / /
     of a Group (See Instructions)           (b)  / /
- -------------------------------------------------------------------------------
 (3) SEC Use Only

- -------------------------------------------------------------------------------
 (4) Citizenship or Place of Organization
     State of Washington
- -------------------------------------------------------------------------------
 Number of Shares             (5) Sole Voting Power
 Beneficially                       0
 Owned by                    --------------------------------------------------
 Each Reporting               (6) Shared Voting Power
 Person With:                       3,492,200
                             --------------------------------------------------
                              (7) Sole Dispositive Power
                                    0
                             --------------------------------------------------
                              (8) Shared Dispositive Power
                                    3,492,200
- -------------------------------------------------------------------------------
 (9) Aggregate Amount Beneficially Owned by Each Reporting Person
                                    3,492,200(2)
- -------------------------------------------------------------------------------
(10) Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See
     Instructions)        / /
- -------------------------------------------------------------------------------
(11) Percent of Class Represented by Amount in Row (9)
                                    7.532%
- -------------------------------------------------------------------------------
(12) Type of Reporting Person (See Instructions)
                                    HC
- -------------------------------------------------------------------------------

- -------------
(2)  The Reporting Person disclaims any beneficial ownership of the shares
     reported on this joint 13G. The reported shares are owned beneficially
     by registered investment ocmpanies for which a subsidiary of the Reporting
     Person serves as adviser and by employee benefit plans for which the  
     Reporting Person is a plan sponsor.

                                 Page 4 of 8


<PAGE>

CUSIP No. 26632S109
          ---------

ITEM 1.

    (a)   Name of Issuer

          See front cover
          ---------------------------------------------------------------------
    (b)   Address of Issuer's Principal Executive Offices

          5880 Pacific Center Blvd., San Diego, CA 92121
          ---------------------------------------------------------------------


ITEM 2.

    (a)   Name of Person Filing

          See Item 1 on cover page (pp 2-4)
          ---------------------------------------------------------------------
    (b)   Address of Principal Business Office or, if none, Residence

          SAFECO Common Stock Trust: 10865 Williows Road NE, Redmond, WA 98052
          SAFECO Corporation: SAFECO Plaza, Seattle, WA 98185
          SAFECO Asset Management Company: 601 Union Street, Suite 2500,
            Seattle, WA 98101
          ---------------------------------------------------------------------
    (c)   Citizenship

          See Item 4 on cover page (pp2-4).
          ---------------------------------------------------------------------
    (d)   Title of Class of Securities

          See front cover page.
          ---------------------------------------------------------------------
    (e)   CUSIP Number
    
          See front cover page.
          ---------------------------------------------------------------------

ITEM 3.  IF THIS STATEMENT IS FILED PURSUANT TO SECTIONS 240.13d-1(b) OR
         240.13d-2(b) OR (c), CHECK WHETHER THE PERSON FILING IS A:

    (a) / / Broker or dealer registered under section 15 of the Act
            (15 U.S.C. 78o).

    (b) / / Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

    (c) / / Insurance company as defined in section 3(a)(19) of the Act
            (15 U.S.C. 78c).

    (d) /X/ Investment company registered under section 8 of the Investment
            Company Act of 1940 (15 U.S.C. 80a-8).

    (e) /X/ An investment adviser in accordance with section
            240.13d-1(b)(1)(ii)(E).

    (f) / / An employee benefit plan or endowment fund in accordance with
            section 240.13d-1(b)(1)(ii)(F).

    (g) /X/ A parent holding company or control person in accordance with
            section 240.13d-1(b)(1)(ii)(G).

    (h) / / A savings association as defined in section 3(b) of the Federal
            Deposit Insurance Act (12 U.S.C. 1813).

    (i) / / A church plan that is excluded from the definition of an investment
            company under section 3(c)(14) of the Investment Company Act of 1940
            (15 U.S.C. 80a-3).

    (j) / / Group, in accordance with section 240.13d-1(b)(1)(ii)(J).


                                 Page 5 of 8


<PAGE>

CUSIP No. 26632S109
          ---------

ITEM 4.  OWNERSHIP

    Provide the following information regarding the aggregate number and
percentage of the class of securities of the issuer identified in Item 1.

          Items (a) through (c): See items 1 and 5-11 of the cover pages 
          (pp 2-5).

          SAFECO Asset Management Company and SAFECO Corporation
          expressly declare that the filing of this statement on
          Schedule 13G shall not be construed as an admission
          that they are, for the purposes of Section 13(d) or
          13(g) of the Securities and Exchange Act of 1934, the
          beneficial owners of any securities covered by this
          statement.  Each of such companies is filing this
          statement because it is considered an indirect
          beneficial owner of such securities based on its
          ownership or control of one or more investment
          companies which directly own such shares.

    (a) Amount beneficially owned:

    ---------------------------------------------------------------------------

    (b) Percent of class:

    ---------------------------------------------------------------------------

    (c) Number of shares as to which the person has:

          (i) Sole power to vote or to direct the vote

              -----------------------------------------------------------------
         (ii) Shared power to vote or to direct the vote

              -----------------------------------------------------------------
        (iii) Sole power to dispose or to direct the disposition of

              -----------------------------------------------------------------
         (iv) Shared power to dispose or to direct the disposition of

              -----------------------------------------------------------------

ITEM 5.  OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

    If this statement is being filed to report the fact that as of the date
hereof the reporting person has ceased to be the beneficial owner of more than
five percent of the class of securities, check the following.  / /

    Not applicable.

ITEM 6.  OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON

    Not applicable.

ITEM 7.  IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED
         THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

         SAFECO Asset Management Company is the subsidiary on
         which SAFECO Corporation is reporting as the parent
         holding company.  SAFECO Asset Management Company is an
         investment adviser as specified in Item 12 on the cover
         page (p. 3), and reported shares are owned beneficially
         by registered investment companies for which SAFECO
         Asset Management Company serves as investment adviser.

ITEM 8.  IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

    Not applicable.

ITEM 9.  NOTICE OF DISSOLUTION OF GROUP
 
    Not applicable.


ITEM 10. CERTIFICATION

    (a)  The following certification shall be included if the statement is filed
pursuant to section 240.13d-1(b):

         By signing below I certify that, to the best of my
         knowledge and belief, the securities referred to above
         were acquired and are held in the ordinary course of
         business and were not acquired and are not held for the
         purpose of or with the effect of changing or
         influencing the control of the issuer of such
         securities and were not acquired and are not held in
         connection with or as a participant in any transaction
         having that purpose or effect.


                                 Page 6 of 8


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CUSIP No. 26632S109
          ---------          

                                   EXHIBITS.

     The statement required by Rule 13d-1(f) is attached as Exhibit A.


                                  SIGNATURE.

    After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.



Date: September 10, 1998           SAFECO Corporation


                                   By /s/ Ronald L. Spaulding        
                                      --------------------------------
                                      Ronald L. Spaulding, Treasurer



                                   SAFECO Common Stock Trust


                                   By /s/ Ronald L. Spaulding      
                                      --------------------------------
                                      Ronald L. Spaulding, Treasurer   

     

                                   SAFECO Asset Management Company


                                   By /s/ Neal A. Fuller             
                                      --------------------------------
                                      Neal A. Fuller, Secretary

                                 Page 7 of 8


<PAGE>

CUSIP No. 26632S109
          ---------          

                                  EXHIBIT A

Agreement for filing Schedule 13-G.

Pursuant to the requirements of Regulation 13d-1(d), SAFECO Corporation, 
SAFECO Asset Management Company, and SAFECO Common Stock Trust each agree 
that Schedule 13-G filed by them with regard to Dura Pharmaceuticals' common 
stock is filed on behalf of each of them.



Date: September 10, 1998           SAFECO Corporation


                                   By /s/ Ronald L. Spaulding        
                                      --------------------------------
                                      Ronald L. Spaulding, Treasurer



                                   SAFECO Common Stock Trust


                                   By /s/ Ronald L. Spaulding        
                                      --------------------------------
                                      Ronald L. Spaulding, Treasurer
                              
                              
   
                                  SAFECO Asset Management Company
 

                                  By  /s/ Neal A. Fuller            
                                      --------------------------------
                                      Neal A. Fuller, Secretary


                                 Page 8 of 8




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