INTERNATIONAL MUREX TECHNOLOGIES CORP
10-K, 1998-03-11
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                  SECURITIES AND EXCHANGE COMMISSION
                        Washington, D.C. 20549

                               FORM 10-K

       [X] ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934 For the Fiscal Year Ended December 31,
1997

     [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934 For the Transition period from ____ to
____

                    Commission File Number 0-26144
                                           -------

             INTERNATIONAL MUREX TECHNOLOGIES CORPORATION
        ------------------------------------------------------
        (Exact name of registrant as specified in its charter)

   BRITISH COLUMBIA, CANADA                           NOT APPLICABLE
   -----------------------------------------------------------------
    (State or other jurisdiction of incorporation or organization)
               (I.R.S. Employer Identification Number)

                 2255 B. QUEEN STREET EAST, SUITE 828
                       TORONTO, ONTARIO M4E 1G3
    --------------------------------------------------------------
    (Address, including zip code, of principal executive officers)

                            (519) 836-8016
              -------------------------------------------
         (Registrant's telephone number, including area code)

      Securities registered pursuant to Section 12(b) of the Act:

                                 NONE

      Securities registered pursuant to Section 12(g) of the Act:

                      COMMON SHARES, NO PAR VALUE

                        SHAREHOLDER RIGHTS PLAN

Indicate by check mark whether the Registrant (1) has filed all
reports required to be filed by Section 13 or 15(d) of the Securities
Exchange Act of 1934 during the preceding 12 months, and (2) has been
subject to such filing requirements for the past 90 days. Yes X     No    .
                                                             ---       ---

Indicate by check mark if disclosure of delinquent filers pursuant to
Item 405 of Regulation S-K is not contained herein, and will not be
contained, to the best of the Registrant's knowledge, in the
definitive proxy statement incorporated by reference in Part III of
this Form 10-K or any amendment to this Form 10-K. [ ]

The aggregate market value of the Registrant's outstanding Common
Shares held by non-affiliates of the Registrant as of March 5, 1998
was U.S. $146,495,755. There were 16,742,372 Common Shares outstanding
as of March 5, 1998.

                 DOCUMENTS INCORPORATED BY REFERENCE:
                 -----------------------------------

Portions of the Registrant's Proxy Statement for the Annual General
Meeting of Shareholders to be held on June 4, 1998 are incorporated by
reference in Part III hereof.



                             Page 1 of 47
                                       ----
                     Index of Exhibits on Page 47



             INTERNATIONAL MUREX TECHNOLOGIES CORPORATION
                      Annual Report on Form 10-K
              For the Fiscal Year Ended December 31, 1997


                           Table of Contents
                           -----------------

Item                                                                       Page
Number                                                                    Number
- ------                                                                    ------

                                              PART I

1.             Business                                                        3
               ..............................................
               ..............................................

2.             Properties                                                     10
               ..............................................
               ..............................................

3.             Legal Proceedings                                              10
               ..............................................
               ..............................................

4.             Submission of Matters to a Vote of Security                    10
               Holders
               ..............................................

                                PART II

5.             Market for the Registrant's Common Shares and                  11
               Related Shareholder Matters....................

6.             Selected Financial Data                                        12
               ..............................................
               ..............................................

7.             Management's Discussion and Analysis of                        13
               Financial Condition and Results of Operations
               ..............................................
               ..............................................

8.             Financial Statements and Supplementary Data                    17
               ..............................................

9.             Changes in and Disagreements with Accountants                  38
               on Accounting and Financial
               Disclosure
               ..............................................
               ..............................................

                               PART III

10.            Directors and Executive Officers of the                        38
               Registrant
               ..............................................

11.            Executive Compensation                                         38
               ..............................................
               ..............................................

12.            Security Ownership of Certain Beneficial                       38
               Owners and Management ........................

13.            Certain Relationships and Related Transactions                 38
               ..............................................

                                PART IV

14.            Exhibits, Financial Statements, and Reports on
               Form 8-K                                                       39
               ..............................................

               Signatures                                                     43
               ..............................................
               ..............................................

               Index of Exhibits                                              47
               ..............................................
               ..............................................



This Form 10-K contains forward-looking statements within the meaning
- ---------------------------------------------------------------------
of Section 27A of the Securities Act of 1933 and Section 21E of the
- -------------------------------------------------------------------
Securities Exchange Act of 1934. The actual results could differ
- ----------------------------------------------------------------
materially from those set forth in the forward- looking statements.
- -------------------------------------------------------------------
Certain factors that might cause such a difference are discussed in
- -------------------------------------------------------------------
the introductory paragraph to Item 7, "Management's Discussion and
- ------------------------------------------------------------------
Analysis of Financial Condition and Results of Operations," within
- ------------------------------------------------------------------
this report.
- ------------


                                PART I
ITEM 1.   BUSINESS

GENERAL

     International Murex Technologies Corporation ("IMTC"), has many
incorporated subsidiaries operating throughout the world generally
under the Murex name (the "Murex Group"). The Murex Group develops,
manufactures and markets medical diagnostic products and provides
medical services for the screening, diagnosis and monitoring of
infectious diseases and other medical conditions.

     In February 1992, the Murex Group acquired all the operating
assets and assumed certain related liabilities of the diagnostics
division of The Wellcome Foundation Limited ("Wellcome"). As a result
of this acquisition, IMTC was converted from a research and
development company with a blood banking operation selling products
through an international distributor network to a holding company
which conducts business in a dozen major world currencies via its
subsidiaries with manufacturing capabilities and an international
direct sales force.

     The Murex Group performs research, develops and manufactures in
vitro diagnostic products mainly in the United Kingdom and markets
them throughout the world, using 15 distribution centers supporting a
direct sales force in 35 countries and a distributor network in more
than 100 countries. The Murex Group also distributes products
manufactured by third parties. Currently, the Murex Group markets
diagnostic tests, reagent components, and systems for use in clinical
laboratories and blood banks. The Murex Group sells approximately 110
products in the United States which meet the U.S. Food and Drug
Administration ("FDA") requirements. The Murex Group does not
presently intend to market its remaining products in the United
States.

     The majority of the Murex Group's products and technologies
relate to two primary product groups: virology and bacteriology assays
for screening, diagnosis and monitoring of infectious diseases.
Worldwide sales of blood viral tests for HIV, Human T- Cell
Lymphotropic Virus ("HTLV") and hepatitis constituted approximately
39%, 42% and 51% of the Company's revenue during 1997, 1996 and 1995,
respectively.

RECENT DEVELOPMENTS

Abbott Litigation

     On or about July 1, 1996, Murex Diagnostics Corporation ("MDC"),
a subsidiary within the Murex Group, filed a patent infringement suit
against Abbott Laboratories ("Abbott") in the District Court for the
Northern District of Georgia (No. 96- CV1676), seeking injunctive
relief against Abbott and damages for infringement of a patent held by
MDC for a particle bound binding component immunoassay. The suit
alleges that two Abbott systems, the Abbott IMx(TM) Immunoassay and
the Abbott AxSYM(TM) System, infringe one or more claims of MDC's
patent. In October 1997, a Summary Judgment motion to dismiss the case
that was filed by Abbott was denied in all aspects. Abbott
subsequently moved for reconsideration of this ruling on the Summary
Judgment; however, a decision on Abbott's motion for reconsideration
is still pending. A trial date has not yet been set, but may occur in
late 1998.

Worldwide Launch of LiPA(R) HIV-1 Reverse Transcriptase Test

     In conjunction with an important strategic alliance partner,
Innogenetics NV ("Innogenetics"), the LiPA (R) HIV-1 Reverse
Transcriptase ("HIV-RT") test was launched worldwide during May 1997.
This test is the first-ever commercially available, rapid assay that
simultaneously identifies HIV resistance associated with the drugs
AZT, ddI, ddC and 3TC. These reverse transcriptase drugs are currently
being utilized, separately and in combination, to treat HIV patients.
Unfortunately, the success of these therapies is greatly jeopardized
if a patient develops resistance to one or more of the drugs.
Resistance occurs as the HIV virus develops mutations that may
eventually cause the drug, or combination of drugs, to become
ineffective against the virus. Resistance mutations occur with all the
approved HIV drugs. Therefore, it is critical to monitor the
development of mutations so therapies can be appropriately combined
and adjusted. With the introduction of the LiPA(R) HIV-1 RT test,
physicians and healthcare providers will have a rapid assay to monitor
the development of key HIV mutations.

     The LiPA(R) HIV-1 RT test provides crucial information relating
to the development of resistance to individual and combination
therapy. By obtaining resistance information, physicians can avoid
using drugs that may not be effective and improve patient care by
selecting more appropriate therapy based on resistance knowledge. In
addition, the expense of unnecessary and ineffective therapy is
eliminated. Furthermore, a physician may utilize resistance
information prior to starting or changing therapy by screening a
patient for the presence of existing drug resistant mutations. See
"Business - Patient Monitoring Products" for further discussion.

South African Manufacturing Facility

     The Murex Group has constructed and opened a new, high technology
manufacturing facility near Johannesburg, South Africa. The new plant
contains state-of-the-art laboratories for production, quality
assurance and research and development, and includes warehousing and
administrative offices. The new site has already been ISO 9002
certified for its manufacturing and distribution systems. It is the
Murex Group's third manufacturing facility, built to international
manufacturing and quality specifications, including those of
regulatory authorities. The facility will manufacture blood screening
and medical diagnostics products with particular emphasis on HIV and
Hepatitis C ("HCV"). The Murex Group plans to export over 80% of the
products manufactured at the new facility to other African countries
and elsewhere throughout the world.

Sale of Certain Technologies

     During June 1997, the Murex Group sold TTP Corporation ("TTP"), a
wholly-owned subsidiary of MDC, to Shield Diagnostics Group plc.
("Shield"). TTP owned the intellectual property and other rights to
ten products used for the diagnosis of thyroid dysfunction and the
measurement of cardiovascular/blood coagulation degradation products.
TTP's assays are targeted to a specific segment of the diagnostics
industry that is not a part of the Murex Group's long-term strategy of
focusing on the screening, diagnosis and monitoring of infectious
diseases. Therefore, the divestiture of TTP is an element of the Murex
Group's overall plan that will allow it to focus its resources on the
infectious disease diagnostics monitoring market. The Murex Group will
continue to manufacture and sell the TTP product line acquired by
Shield for a period of three years, pursuant to a purchase commitment.
This will provide Shield security regarding availability of the
products while they are being integrated into Shield's business, as
well as permit Shield to utilize the Murex Group's worldwide
distribution network.

IMMUNODIAGNOSTIC PRODUCTS

     The health care industry is comprised of four main sectors:
diagnostics, therapeutics, preventive medicine, and health services.
The diagnostics sector involves the diagnosis or detection of specific
diseases or medical conditions. Proper therapy or treatment can only
be provided following an accurate diagnosis of these underlying
diseases or conditions. Diagnostics cover a wide range of products and
services, including items such as X-ray equipment, blood pressure
measurement equipment, analytical chemistry equipment and
immunodiagnostics.

     Immunodiagnostics is the field of diagnostics that employs the
reactions between antibodies and antigens as the basis of tests for
the detection of specific diseases and other medical conditions.
Antibodies are proteins in human or animal blood that are produced by
the immune system in response to exposure to foreign substances or
antigens such as bacteria and viruses. Antibodies and antigens are
complementary with each antibody being directed against, and reacting
with, one specific type of antigen. Antibodies will react with
antigens at very low concentrations, and it is these unique
characteristics that give immunodiagnostic tests their high degree of
sensitivity and specificity.

     The Murex Group's immunodiagnostic product line includes over 600
diagnostic tests, reagent components and systems. Approximately 39%,
42% and 51% of IMTC's revenue for 1997, 1996 and 1995, respectively,
was generated from the sale of virology diagnostics to detect HIV-1
and HIV-2 (the viruses causing AIDS), HTLV-I and II, and hepatitis A,
B and C infections. The Murex Group also markets bacteriology products
worldwide to detect such bacterial infections as strep throat and
salmonella poisoning. United States sales of bacteriology products
account for approximately 15% of the Murex Group's sales. Trade names
of these products include Wellcogen(TM), Wellcolex(TM),
Staphaurex(TM), REVEAL(TM), and Streptex(TM). The Murex Group
developed an in vitro, immunodiagnostic rapid test system, the Single
Use Diagnostic System, or SUDS(R), that can be used to diagnose
numerous specific diseases or medical conditions. The SUDS (R) HIV
test sales increased 42% during 1997 as compared to 1996, as interest
in this rapid test continues to grow due to new guidelines recently
published by the Center for Disease Control regarding occupational
exposure to HIV by healthcare professionals. The SUDS(R) HIV-1 test
was cleared by the FDA in 1992. In late 1993, the SUDS(R) HIV 1+2 test
was introduced by affiliated companies for sale in Europe. The HIV 1+2
test is not currently available, nor planned, for sale in the United
States and certain other countries because of regulatory and other
restrictions. The Murex Group's product introductions during 1995,
1996 and 1997 include HTLV I and II antibody detection assay, syphilis
antibody test, hepatitis C western blot, therapeutic drug
monitoring-quality assessment program, mycoplasma pneumonia antibody
detection kit, HIV 1+2 type O antibody test, Digene Sharps probe
assays, E-coli, Cryptococcus, Staphaurex Plus assays and Sample
Addition Monitor ("SAM(TM)"). See "Business - Patents, Trademarks and
Licenses".

PATIENT MONITORING PRODUCTS

     During February 1996, MDC entered into an exclusive distribution,
development and license agreement with Innogenetics to develop and
market gene probe products for the monitoring of patients and the
classification of viral diseases. This strategic alliance with
Innogenetics has provided the Murex Group with exclusive rights to the
Murex/Innogenetics LiPA(R) HIV-RT monitoring test. This test
simultaneously detects wild-type and HIV mutations associated with the
reverse transcriptase drugs AZT, ddI, ddC and 3TC. The Murex Group
launched the test world-wide, except in the U.S. and France where the
product is distributed for research use only, late in the second
quarter of 1997. In the U.S., Murex Diagnostics, Inc. ("MDI") has had
discussions with the FDA but has not yet filed an application for the
clearance of the test.

     The reverse transcriptase drugs AZT, ddI, ddC and 3TC are
currently being utilized, separately and in combination, to treat HIV
patients. Resistance to the drugs occurs as virus mutations develop
that may eventually cause the drug, or a combination of drugs, to
become ineffective against the virus. The Murex/Innogenetics LiPA (R)
HIV-1 RT test is the first rapid assay to identify HIV mutant strains.

     Resistant mutations occur with all the approved HIV therapies.
Therefore, it is critical to monitor the development of mutations so
therapies can be appropriately combined and adjusted. The new HIV-1 RT
test provides crucial information relating to the development of
resistance to individual and combination therapy. By obtaining
resistance information, physicians can avoid using drugs that may not
be effective, thereby improving patient care and eliminating the
expense of unnecessary and ineffective therapy. In addition, a
physician may utilize resistance information prior to starting or
changing therapy by screening a patient for the presence of existing
drug resistant mutations.

     The broadening of the Murex Group's focus into the world-wide
emerging diagnostics monitoring market, which management expects to
exceed $1 billion by the year 2000, should support revenue growth in
the coming years. The Innogenetics distribution, development and
licensing agreement gives the Murex Group access to the rapidly
growing gene probe market for monitoring patients and the
classification of viral diseases. The monitoring market directly
complements the Murex Group's existing markets of screening and
diagnosis and also leverages its worldwide marketing and distribution
network. The diagnostic monitoring market includes tests that, among
other applications, assess a patient through the course of a disease
or infection, monitor various forms of anti-viral therapies and
monitor conditions associated with transplants. In contrast, screening
and diagnosis tests are used to indicate whether a patient is, or is
not, carrying a disease or infection. In patient use, screening and
diagnosis tests are usually only required to be administered once
while monitoring tests are usually administered numerous times.

     Patient monitoring has become an important and critical element
of patient care and treatment. The Murex Group believes it can capture
a significant portion of this emerging market by strategically
positioning itself in key segments of the market including AIDS
therapy, organ transplantation and other immune compromised
conditions.

     In addition to the agreement above, during May 1997 the Company
licensed its trademarked SAM(TM) technology to Innogenetics. The
color-coded SAM(TM) technology will be utilized in Innogenetics'
enzyme immunoassay products (EIA) with the first being Innogenetics'
HIV Ag assay. Developed by Murex's internal research and development,
SAM(TM)'s color-coded reagents change color in each testing step of an
assay. The technology assists clinicians in ensuring that samples have
been added and the testing procedure has been conducted correctly. The
Murex Group's SAM(TM) technology is utilized in selected Murex
products and it has been licensed to a number of large healthcare
companies, including Chiron Corporation.

ADDITIONAL STRATEGIC ALLIANCES

     As the relationship with Innogenetics demonstrates, management
believes strategic ventures and licensing arrangements position the
Murex Group for the future and play an important role in the
achievement of management's corporate objectives. The worldwide
marketing and distribution capabilities motivate companies like
Innogenetics, Digene Corporation ("Digene"), Eurogenetics N.V.
("Eurogenetics") and Genelabs Diagnostics SA ("Genelabs") to partner
with the Murex Group in licensing agreements and product development
and thereby contribute to the flow of new and creative products. The
alliances provide the Murex Group with access to technology,
strengthen and extend the monitoring market strategy and allow the
Murex Group to further penetrate its existing markets in blood
screening and clinical diagnostics.

Digene Corporation

     Effective February 1997, the Murex Group and Digene entered into
a five year agreement to work together to create a direct European
sales operation for Digene's sexually transmitted disease diagnostics
business. Digene, a leading developer of DNA probe technology, will
sell its Hybrid Capture(R) human papillomavirus ("HPV") DNA test
directly in selected European markets using the Murex Group's existing
distribution infrastructure in exchange for agency and selling service
fees. Additionally, Digene will make fixed payments over two years for
the European HPV business. The strategic alliance with Digene was
further extended during the year whereby the Murex Group received
exclusive rights to market Digene's new Hybrid Capture (R) II HIV RNA,
Cytomegalovirus ("CMV") and Hepatitis B ("HBV") tests in the United
Kingdom, Europe, Africa, the Middle East and Singapore, following
receipt of appropriate import and export authorizations from the FDA
and relevant foreign authorities.

Eurogenetics N.V.

     During January 1997, MDC entered into a ten year, worldwide
Original Equipment Manufacturer ("OEM") distribution agreement with
Eurogenetics. Pursuant to the terms of the agreement, the Murex Group
will distribute Eurogenetics' micro titre plate EIA kits for rubella,
toxoplasmosis, CMV, chlamydia, herpes and beta- 2 microglobulin.

Genelabs Diagnostics SA

     Effective June 1997, Genelabs, of Geneva, Switzerland, appointed
MDC to handle distribution of its diagnostics products in Europe and
South America. The move is expected to benefit hospitals and
laboratories in terms of product availability and technical support,
and expand the supply of Genelabs' speciality tests for the diagnosis
of infectious diseases and immunological disorders to new areas of
need. Agreements made between the two companies, which are exclusive
or co-exclusive depending on the country, provide for the sale of
viral confirmatory tests including, Western Blots for HTLV, HIV,
Epstein-Barr Virus ("EBV") and CMV, Autoblot 36 and Western Blot
instrumentation, as well as Hepatitis E Elisa.

MARKETING AND COMPETITION

     The immunodiagnostic systems industry is fragmented and very
competitive. It consists of large multinationals with very entrenched
market positions and many small to medium size companies competing
within specific market segments. The industry is experiencing some
concentration as some of the larger companies merge or acquire smaller
companies. Within the infectious disease market, segmentation exists
both by product group and the type of testing to be performed: mass
screening tests, confirmatory tests and rapid diagnostic tests. The
Murex Group's products compete in all these market segments. Principal
customer types in the infectious disease market include blood banks,
hospitals, clinical diagnostic laboratories and physicians' offices.
Principal competitors in the high volume mass screening market are
Abbott Laboratories, Ortho Diagnostic Systems, Genetic Systems and
Organon Teknika. Principal competitors in the rapid assay market are
Hybritech, Becton- Dickinson and Abbott Laboratories.

     The Murex Group possesses a significant portfolio of proven
products and technologies. Approximately 74% of product sales are
concentrated in Europe and the United States. Murex Group sales are
supported by regional distribution centers serving direct sales forces
in the United States, the United Kingdom, Germany, Italy, Spain,
France, Switzerland, the Czech Republic, the Netherlands, Canada,
Argentina, Columbia, Brazil, Australia and South Africa. The Murex
Group is represented in the rest of the world by a network of direct
sales representatives, distributors and agents.

     No single customer represented more than 5% of total sales in
1997. For further information concerning IMTC's or the Murex Group's
domestic and foreign operations, see Note 19 to the Consolidated
Financial Statements.

RESEARCH AND DEVELOPMENT

     The principal focus of the Murex Group's research and development
efforts has been and will continue to be the development of
high-volume assays for the detection of infectious agents such as
HTLV, HIV and hepatitis using advanced enzyme immunoassay
technologies. Also, under the terms of the 1992 acquisition of the
diagnostics division of Wellcome, Wellcome agreed to collaborate with
the Murex Group and grant first right of access to future
technological discoveries applicable to medical diagnostics through
February 1997. Pursuant to this agreement, MDC has entered into a
semi-exclusive patent licensing agreement with Glaxo-Wellcome relating
to testing for resistance to AZT.

     During February 1996, MDC entered into an exclusive distribution,
development and license agreement with Innogenetics to develop and
market gene probe products for the monitoring of patients and the
classification of viral diseases. Under the terms of the agreement,
MDC paid $5.9 million during 1996 and $1.6 million during 1997 to
Innogenetics for the exclusive rights to distribute Innogenetics'
LiPA(R) products, excluding HCV, for 15 years. MDC will also pay
Innogenetics a royalty of 10% of the Murex Group's net sales of
Innogenetics' products. Also under this agreement, MDC will fund
agreed-upon research and development programs, beginning in 1998 and
for each of the following 13 years in an amount equal to 20% of the
Murex Group's net sales of Innogenetics' products, subject to a cap.
This strategic alliance with Innogenetics has provided the Murex Group
exclusive rights to the Murex/Innogenetics HIV-RT monitoring test. In
the U.S., MDI has had discussions with the FDA but has not yet filed
an application for the approval of the test. The Murex/Innogenetics
LiPA(R) HIV-1 RT test is the first rapid assay to measure mutant
strains. See "Business - Patient Monitoring Products" for further
information.

     The Murex Group's internal research and development remains
strong as evidenced by its HTLV, syphilis, E. Coli 0157, redeveloped
HIV and HCV tests and other new product introductions. The Murex Group
incurred in-house and third party research and development expenses
aggregating $7,487,000, $6,369,000 and $7,426,000 for the years ended
December 31, 1997, 1996, and 1995, respectively.

MANUFACTURING OPERATIONS

     Worldwide distribution and sales of the majority of the Murex
Group's products originate from Murex Biotech Limited's ("MBL")
manufacturing facility, which is located in Dartford, England, under a
contract manufacturing and services agreement with MDC. Several
products sold by the Murex Group are produced by third party
manufacturers located throughout the world. Raw materials are produced
or acquired from independent suppliers and assembled into finished
products. MBL is fully compliant with the European Economic Community
ISO 9001 manufacturing and design standards. See "Business--Government
Regulation".

     As discussed in the "Business - Recent Developments" section, the
Murex Group recently constructed and opened a manufacturing plant near
Johannesburg, South Africa which is ISO 9002 certified for its
manufacturing and distribution systems.

     MDI operates under Good Manufacturing Practices ("GMP")
guidelines which outline the manufacturing, quality control, quality
assurance and documentation standards mandated by the FDA for a
medical products company. The components of the SUDS(R) test cartridge
and reagent raw materials are purchased by MDI from suppliers and
contract manufacturers and are assembled by MDI. Currently there are
no material adverse effects on capital expenditures, earnings or Murex
Group's competitive position due to compliance with federal, state and
local environmental regulations. See "Business-Government Regulation".

PATENTS, TRADEMARKS, AND LICENSES

     Patents and other proprietary technology are important to
biotechnology companies. Extensive research on a worldwide scale by
many companies has led to competitive claims of technology and patents
ownerships. The Murex Group's assets include a comprehensive patent
and license portfolio. Most of these patents and licenses are owned by
MDC. Patented latex agglutination technologies owned by the Murex
Group serve as the base technologies for the REVEAL and Wellcolex
bacterial product lines. License agreements with the Murex Group as
licensee include technologies and patents covering areas such as HIV-2
and hepatitis B core.

     The Murex Group's business utilizes newly developed technologies
that include patents on processes and devices. These types of
technologies are the focal point for the biotechnology industry. The
ownership and patentability of such processes or devices have become
increasingly complex, resulting in competitive claims of ownership
within the industry.

     As part of a 1996 agreement with Chiron Corporation ("Chiron")
and Ortho Diagnostics Systems, Inc. ("Ortho"), the Murex Group,
through MDC, has a license to sell HCV Serotyping tests worldwide and
other HCV tests in selected countries excluding North America,
European Union members and Japan. The agreement also grants to the
Chiron-Ortho joint business rights to MDC's SAM(TM) technology and an
option to sell MDC's HCV Serotyping test. The agreement also provides
Chiron the opportunity to acquire the Murex Group's HCV immunoassay
business at its then fair value in the event IMTC accepts an offer to
purchase 50% or more of the combined voting power of IMTC's then
outstanding securities, or if IMTC's Board of Directors approves a
merger, or the sale of all, or substantially all, of the Murex Group's
assets. If Chiron does not exercise this option, IMTC is entitled to
transfer its rights and licenses under the agreement described above.

     "Wellcogen", "Wellcolex", "Staphaurex", "Staphaurex Plus",
"Streptex", "REVEAL", "Murex", "SUDS" and "SAM" are among the
registered or licensed trademarks of the Murex Group. MDC has also
applied for a trademark for "Information for Life". Under the terms of
the acquisition of the diagnostics division of Wellcome, the Murex
Group has the right to continue to use the name "Well" in connection
with acquired products until August 2000.



     The Murex Group, largely through MDC, holds various patents on
current and potentially valuable technologies in multiple countries.
The exploitation of the potential value of this intellectual property
is anticipated through a combination of product development and/or
licensing of technology for use by others.

     MDC has licensed certain of its patented technologies to third
parties. MDC completed a non-exclusive, out-licensing transaction
during the second quarter of 1994 by licensing technology, acquired as
part of the 1992 acquisition of the diagnostics division of Wellcome,
to Abbott. This transaction provided MDC with a $10 million minimum
license fee which was paid over four years. Furthermore, MDC earned an
additional $1,075,000, $878,000 and $100,000 in 1997, 1996 and 1995,
respectively, as a result of minimum royalty levels being exceeded.
The underlying revenue stream associated with this licensing agreement
has grown 108% since 1994 and MDC expects the minimum royalty levels
to continue to be exceeded until the expiration of the patents in the
years 2004 and 2008, depending on the country. Beginning in 1998, the
Company anticipates receiving at least $3 million per year from this
licensing arrangement.

     The Murex Group also relies on unpatented technology and
know-how. There can be no assurance that others will not obtain access
to, or independently develop, such know-how. The Murex Group also
protects their proprietary information through confidentiality
agreements executed by all management employees.


GOVERNMENT REGULATION

     The manufacture and marketing of in vitro diagnostic products are
governed by a variety of statutes and regulations in the United States
and by comparable laws and regulations in other countries. Some
countries do not have any such statutes and regulations. The process
mandated by the FDA for clearance of a diagnostic product differs
depending on whether the product is classified as a medical device or
a biological product.

     FDA clearance may be obtained to market medical device products
in the United States through a pre-market notification filing, or
510(k) submission, for a device that is substantially equivalent to
devices on the market. Depending on the device's complexity, the
review period can be in excess of 200 days from the date of filing the
application. Affirmative FDA action is required before marketing may
proceed. Medical devices not substantially equivalent to devices
already on the market must undergo a more elaborate clearance process
requiring the submission to the FDA of an application for pre-market
approval ("PMA") containing substantial technical, manufacturing and
clinical data.

     Clearance by the FDA of a biological product (rather than a
medical device product ) for human use, such as the SUDS(R) HIV-1
test, which was cleared by the FDA in 1992, is a multi-step process.
The process includes: (a) pre-clinical laboratory and animal tests,
(b) submission to the FDA of an application for an Investigational New
Drug exemption ("IND"), which must become effective before human
clinical trials may commence, (c) human clinical trials to establish
the safety and effectiveness of the product, (d) submission to the FDA
of a Product License Application ("PLA"), which summarizes the results
of clinical studies, and a related Establishment License Application
("ELA") for the licensing of the product's manufacturing processes and
facilities, (e) FDA approval of the PLA and ELA, and, (f) FDA
evaluation and release of each manufactured lot prior to distribution.
An ELA provides information on the results of the clinical tests as
well as the details of the manufacturing process, such as raw material
suppliers, manufacturing equipment, quality control and assurance
procedures, and product labeling. Additionally, an ELA discloses the
qualifications of the personnel involved in product development,
manufacturing and testing. FDA's review of an ELA entails examination
of such data and information as well as inspection of the facilities
that will be used for the manufacture of the product. MBL's U.K.
manufacturing facility is ISO 9001 certified. The new facility in
South Africa is ISO 9002 certified for its manufacturing and
distribution systems. ISO 9000 certification is an international
quality management system standard for design, manufacture and
distribution of in vitro diagnostic kits and systems.

     Although the Murex Group anticipates additional FDA clearances
and foreign approvals, it is not possible to estimate when the
application and review processes will be completed with respect to a
given product or facility. There can be no assurance that additional
clearances or approvals from the FDA or other foreign regulators will
be granted.

     The Murex Group is also subject to various federal, state and
local laws and regulations relating to working conditions, laboratory
and manufacturing practices, the experimental use of animals and the
use and disposal of hazardous or potentially hazardous substances,
including radioactive compounds and infectious disease agents, used in
connection with research work and preclinical and clinical trials and
testing. The extent of government regulation which might result from
future legislation or administrative action cannot be accurately
predicted.

EMPLOYEES

     As of January 31, 1998, IMTC and its subsidiaries had 665 full
time employees located world wide, 55 of whom were involved in
research and development, 242 in manufacturing and 280 in sales and
marketing. All other employees perform executive and administrative
functions. Certain Murex Group employees are represented by seven
separate unions which include approximately 56 employees, primarily in
manufacturing and sales in the United Kingdom, Italy and France.
Management considers its relations with all of its employees, both
union and non-union, to be good.

YEAR 2000 SYSTEMS COMPLIANCE

     The Murex Group recognizes that the arrival of the Year 2000
poses a unique challenge to the ability of all systems to recognize
the date change from December 31, 1999 to January 1, 2000 and has
begun to analyze its various administrative and operating systems to
ensure that these systems will be Year 2000 compliant. Many of the
Murex Group's existing systems include new hardware and packaged
software recently purchased from large vendors who have represented
that these systems are already Year 2000 compliant. Management has not
estimated the costs to upgrade the remaining systems, however, they
are not expected to be material to any single year. Management
presently believes that with conversions to new systems and hardware,
the Year 2000 risks can be mitigated. An assessment of the readiness
of external entities, which it interfaces, such as vendors, customers
and others, is ongoing. There can be no guarantee that the systems of
other companies on which the Murex Group's systems rely will be timely
converted, nor that any unforseen costs won't be material to the
operations of the Murex Group.

ITEM 2.  PROPERTIES

     MBL researches, develops, manufactures and ships its products
from a 120,000 square foot facility located in Dartford, England,
leased from Glaxo-Wellcome Limited through 2000, subject to a five
year extension. Murex Biotech SA Limited, one of the Murex Group's
South African subsidiaries, leases a new 16,000 square foot
manufacturing facility close to Johannesburg, South Africa until 2002,
subject to a five year extension. MDI manufactures in a 41,000 square
foot facility located in Norcross, Georgia, leased through 1999.
Executive office and subsidiary sales office leases in various
countries generally expire at various times through 2002.

     The Murex Group believes its facilities are adequate and suitable
for its current and anticipated manufacturing, research, development,
marketing and administrative operations for the foreseeable future.

ITEM 3.  LEGAL PROCEEDINGS

     With the exception of the Abbott patent infringement suit in
which the Murex Group is the plaintiff, as discussed in the "Business
- - Recent Developments" section, the Murex Group is no longer involved
in any other material legal proceedings. The following matters have
been favorably resolved, as discussed below:

CLASS ACTIONS

     Four class action lawsuits were instituted on behalf of all
persons who had purchased IMTC's securities between May 21, 1992 and
August 19, 1992 against IMTC, one former and one present executive
officer of IMTC, and two shareholders. Although the defendants denied
the allegations in the complaints, the parties agreed to settle all
outstanding claims for $5.4 million during 1996. In accordance with
the Stipulation Settlement Agreement, the two shareholders transferred
185,886 common shares of IMTC's stock to IMTC to be used as their
portion of the settlement. During 1997, the claims administrator
finished qualifying claimants and submitted a motion to the U.S.
District court setting out the final distribution for the settlement
fund, which was approved by the Court during October 1997. The sum of
damages claimed and expenses incurred by the claims administrator and
Plaintiffs' counsel was less than the total settlement fund.
Consequently, the Murex Group was entitled to the remaining cash of
approximately $2.1 million and 105,766 common shares of IMTC's stock.
These shares are valued at $615,000 ($5.81 per share), as defined by
the settlement agreement. The reversion of the settlement fund has
been reflected in the accompanying financial statements as an offset
to general and administrative costs for the cash portion and an
increase to additional paid-in capital for the stock portion.

UNITED KINGDOM TAX DISPUTE

     During 1995, the U.K. Inland Revenue questioned the tax basis of
inventory, accounts receivable and property, plant and equipment
related to the 1992 purchase of assets from Wellcome. This matter was
resolved during 1997, resulting in no additional tax payments or
liabilities. The U.K. Inland Revenue have finalized their review of
all tax returns through 1995, and all outstanding issues have been
resolved.


ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

    None.




                                PART II

ITEM 5.  MARKET FOR THE REGISTRANT'S COMMON EQUITY AND RELATED
           SHAREHOLDER MATTERS


     IMTC's Common Shares are listed and traded on the Nasdaq National
Market System ("Nasdaq") under the symbol "MURXF". The following table
sets forth the quarterly high and low closing sale prices of the
Common Shares for the periods noted.


                                               Calendar Year

                                         1997                 1996
- --------------------------------------------------------------------------------
NASDAQ Stock Exchange

(Expressed in U.S
 Dollars)                          High       Low        High        Low
- --------------------------------------------------------------------------------
First Quarter                  $    9.47   $   6.75   $   3.63   $   2.38

Second Quarter                     10.00       6.00       4.63       2.63

Third Quarter                      10.50       8.06       6.38       3.00

Fourth Quarter                     10.13       8.50       7.63       5.25


SHAREHOLDERS

     As of March 5, 1998, IMTC had 16,742,372 Common Shares held by
approximately 1,799 holders of record. The number of holders do not
include all individuals with a beneficial interest in IMTC's Common
Shares.

DIVIDEND POLICY

     IMTC has never paid a cash dividend on its Common Shares and has
no plans to pay cash dividends in the foreseeable future. The policy
of IMTC's Board of Directors is to retain any earnings for use in the
operation and expansion of business. The Bank of America line of
credit facility prohibits the payment of any IMTC dividends except
those paid in Common Shares.

UNREGISTERED SHARES

     During the fourth quarter of 1997, IMTC issued no unregistered
securities.






<PAGE>



ITEM 6.   SELECTED FINANCIAL DATA


<TABLE>
<CAPTION>

- ---------------------------------------------------------------------------------------------------

                                                                 Year Ended December 31,
                                      -------------------------------------------------------------
                                          1997         1996         1995         1994       1993
- ---------------------------------------------------------------------------------------------------
CONSOLIDATED STATEMENTS OF                (In thousands of U.S. Dollars, except per share data)
OPERATIONS DATA
<S>                                   <C>          <C>           <C>          <C>          <C>

Product sales                         $  98,553    $  99,881    $  92,394    $  93,192    $  79,689
License fees                              7,579          970                     9,250           36
                                      -------------------------------------------------------------
Total revenues                          106,132      100,851       92,394      102,442       79,725

Cost and expenses:
    Cost of products sold                39,250       34,887       30,181       24,353       24,368
    Research & development                7,487        6,369        7,426        6,372        5,967
    General & administrative             21,630       25,803       27,541       22,399       15,746
    Sales & marketing                    28,883       29,523       26,898       23,586       22,357
    Royalty expense                       5,625       (2,799)       8,365        9,599        6,430
    Restructuring costs                                2,100
    All other expenses                      104        1,542       (1,016)         547        1,091
                                      -------------------------------------------------------------
Total costs & expenses                  102,979       97,425       99,395       86,856       75,959

Operating income (loss)                   3,153        3,426       (7,001)      15,586        3,766
Interest income                             290          663        1,221          802          285
Interest expense                         (1,422)      (1,306)        (167)        (632)        (917)
All other income (expense), net           7,043         (934)        (663)      (1,532)        (460)
                                      -------------------------------------------------------------

Net income (loss)                     $   9,064    $   1,849    $  (6,610)   $  14,224    $   2,674
                                      =============================================================

Net income (loss) per common share
   Basic                              $    0.55    $    0.11  $     (0.40)   $    0.85    $    0.16
   Diluted                            $    0.52    $    0.11  $     (0.40)        0.85    $    0.16

Weighted average shares outstanding
   Basic, in thousands                   16,484       16,215       16,381       16,661       16,255
   Diluted, in thousands                 17,444       16,507       16,381       16,739       16,340

Cash dividends                                0            0            0            0            0
</TABLE>


<TABLE>
<CAPTION>

                                                               At December 31,
                                      -------------------------------------------------------------
                                          1997         1996         1995        1994        1993
- ---------------------------------------------------------------------------------------------------
CONSOLIDATED                                         (In thousands of U.S. Dollars)
BALANCE SHEET DATA
<S>                                   <C>          <C>           <C>          <C>            <C>

Total assets                          $  95,243    $  95,113    $  85,748    $  85,643    $  58,966

Long term debt                           14,331        9,638            0            0            0

</TABLE>






<PAGE>



ITEM 7. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION
         AND RESULTS OF OPERATIONS

     This report contains or refers to forward-looking information
including future revenues, products and income and is based upon
current expectations that involve a number of business risks and
uncertainties. Among the factors that could cause actual results to
differ materially from any forward-looking statement include, but are
not limited to, technological innovations of competitors, delays in
product introductions, changes in health care regulations and
reimbursements, litigation claims, changes in foreign economic
conditions or currency translation, product acceptance or changes in
government regulation of the Murex Group's products, as well as other
factors discussed in other Securities and Exchange Commission filings
for IMTC.

FINANCIAL CONDITION

     During the year ended December 31, 1997, IMTC and the Murex Group
(collectively referred to herein for consolidated financial purposes
only as the "Company"), continued its profitability, generated cash
from operations and maintained positive working capital.

Litigation and Technology Disputes

     The Murex Group's business utilizes newly developed technologies
that include patents on processes and devices. These types of
technologies are the focal point for the biotechnology industry. The
ownership and patentability of such processes or devices have become
increasingly complex, resulting in competitive claims of ownership
within the industry. The Company is not presently the defendant in any
material judicial proceeding, however, the Company is vigorously
pursuing its patent infringement suit in which the Company is the
plaintiff against Abbott. See "Business - Recent Developments".

Liquidity and Capital Resources

     The Company anticipates that its projected profitability, line of
credit facility, sufficient cash resources and adequate working
capital will enable it to carry on its current business and meet
existing capital requirements over the next twelve months and beyond.
Cash and working capital totaled $10.1 million and $48.9 million,
respectively at December 31, 1997. The Company generated cash from
operations of $6.0 million during the year ended December 31, 1997. On
November 12, 1996, the Company entered into a three year, $15 million
line of credit facility with Bank of America, which is collateralized
by the accounts receivable and inventory of its U.S., U.K. and
Barbados subsidiaries. Based on the value of the collateral, the
borrowings outstanding of $12,996,000 and a letter of credit
outstanding of $825,000, there was $186,000 unused and available under
this credit facility as of December 31, 1997. On January 14, 1998,
management amended the previous interest rate swap agreement with the
lender and fixed the interest rate at 8.98% (LIBOR + 2.5%) for
notional principal amount of $10 million for five years.

     The Company's working capital and capital requirements will
depend upon numerous factors including: the results of research and
development, the levels of resources devoted to the establishment and
expansion of marketing and manufacturing, technological developments,
and the timing and costs of obtaining approvals for new products.
Depending on the outcome of these factors, the Company may need to
raise additional funds in the future for use to complete products in
development or for other general purposes. There are no assurances
that such funds will be available on favorable terms, if at all.

Management Outlook

     The key to the Company's growth is the ability to identify new
needs in the marketplace, and to expeditiously meet these needs
through access to appropriate innovations and technologies, and to
rapidly incorporate them into the Murex Group's product line. However,
there can be no assurance that the Murex Group will successfully add a
significant number of new products to its product line. An alternative
strategy under consideration is to seek to maximize shareholder value
through asset sales or other dispositions. This strategy involves
management balancing its analysis of the Company's future prospects
against any third party proposal. There is no assurance that any third
party proposal would be acceptable to the Company or that management
would continue to explore this alternative.

     The Company is now positioned to benefit from investments made
during 1997 aimed at expansion not only into the patient monitoring
business with new products but also into emerging markets such as
South East Asia, South America and Southern Africa with both
diagnostic and monitoring products. Recent successes in emerging
markets include winning, for the second year, the entire Taiwan Red
Cross tender for over three million HCV, HTLV and HBsAg screening
assays. Also, late in 1997, the Company won a significant tender in
Turkey for 600,000 HCV tests. The Company also anticipates that sales
to South American countries will increase significantly during 1998.
Furthermore, by being the first company to market diagnostic products
which are manufactured in Africa, the Murex Group is positioned to
capitalize on the significant and growing African market.

     Recent Murex Group product innovations, such as SAM(TM), and
tests for HIV, HTLV, syphilis and E-Coli, should contribute to future
sales growth. These and other new or enhanced products, created
through in-house research and development, strengthened the Murex
Group's broad line of well-established virology and bacteriology
products and allowed the Murex Group to enter new markets in targeted
areas around the world.

     In addition to relying on research and development and licensing
of core technologies, management's operation strategy also focuses on
maintaining high quality standards, providing excellent customer
service, reducing costs and improving cash flows.

RESULTS OF OPERATIONS

Year ended December 31, 1997 compared to year ended December 31, 1996

     Total revenues for the year ended December 31, 1997 increased to
$106,132,000 over the prior year's revenues of $100,851,000. This
increase is partially due to the fixed payments made by Digene in
accordance with the February 1997 agreement and the sale of certain
technologies to Shield. An increase in the ongoing royalty revenue
generated from licensing certain technology to Abbott also contributed
to the increased revenues. The technologies sold to Shield are
targeted to a specific segment of the diagnostics industry that is not
part of the Company's long term focused strategy. The strength of the
U.S. Dollar against most major currencies during the year ended
December 31, 1997 relative to the prior year caused a decrease in the
Dollar equivalent product sales revenue. Murex operates a worldwide
distribution network; consequently, approximately 68% of the Company's
product sales are denominated in currencies other than the U.S.
Dollar, the reporting currency of the Company. The changes in product
sales represent actual increases, using a constant currency basis, of
$3,812,000, offset by negative foreign exchange impacts of $5,140,000
for the year ended December 31, 1997. License fees and royalties
increased to $7,579,000 from $970,000 in the previous year, as a
result of the Abbott, Digene and Shield agreements discussed above.

     Gross profit on product sales was 60.2% and 65.1% for the years
ended December 31, 1997 and 1996, respectively. The cost of products
sold was $39,250,000 and $34,887,000 the years ended December 31, 1997
and 1996, respectively. The increase in cost of goods sold is
primarily due to the strength of the British Pound, which also
strengthened against most major currencies during 1997, since the
majority of manufacturing is done in the U.K.
                                            
     Total costs and expenses, excluding cost of products sold, of
$63,729,000 for the year ended December 31, 1997 reflect a net
increase of $1,191,000 over the year ended December 31, 1996. Research
and development costs for 1997 were increased by $1,118,000 due to the
Company's strategy of developing innovative products for its
distribution network and continuously improving its existing products.
During 1997, the Company focused significant research and development
on improving its HIV and HCV test design and manufacturing process to
meet the changing requirements of this important market. General and
administrative expenses decreased $4,173,000 to $21,630,000 for 1997
as compared to $25,803,000 for 1996. The previous year's general and
administrative expenses included legal, employee compensation, and
other expenses associated with settling the patent litigation related
to its HCV test. As discussed in Note 16 of the accompanying financial
statements, the Company received the reversion of the class action
settlement fund, of which the cash portion of $2,133,000 is considered
as a reduction to general and administrative expenses in 1997. Sales
and marketing expenses were $28,883,000 and $29,523,000 for the years
ended December 31, 1997 and 1996, respectively. The decrease of
$640,000 was due to the effect of translating foreign currencies to a
stronger U.S. Dollar. The foreign exchange loss for the year ended
December 31, 1997 was $104,000 compared with a loss of $1,542,000 for
1996. The 1996 foreign exchange losses were caused predominantly by
the strengthening of the British Pound in relation to the U.S. and
German currencies, as well as the weakening of the South African Rand.
The royalty expense for the year ended December 31, 1997 was
$5,625,000 versus a net credit of $2,799,000 for 1996. As a result of
the settlement of HCV patent litigation during the third quarter of
1996, a reversal was made to royalty accruals made in previous years,
which resulted in a net credit to royalty expense. During September
1996, the Company recorded a restructuring charge of $2.1 million
before tax. The restructuring was driven by the need to reposition the
Company for its movement into the patient monitoring business, and
consisted predominantly of estimated costs for employee severance and
other benefits.

     Net interest expense for the year ended December 31, 1997 was
$1,132,000 compared to $643,000 for the year ended December 31, 1996.
The Company currently has access to capital at favorable rates via the
line of credit with Bank of America, however, during the twelve months
ended December 31, 1997, the Company increased the amount borrowed. In
the prior year, the Company factored its Italian receivables to fund
the agreement with Innogenetics. Other income for the year ended
December 31, 1997 was $3,374,000 compared to $386,000 for the year
ended December 31, 1996. The increase of $2,988,000 was primarily from
realized gains on marketable securities. The gain on liquidation of
investee for the year ended December 31, 1997 of $1,114,000 represents
additional proceeds IMTC expects to receive upon the ultimate
liquidation of SDL. Management expects the liquidation process to be
completed during the first quarter of 1998. These additional proceeds
are the result of the final and favorable settlements of claims with
various tax authorities including U.K. Inland Revenue. The equity in
loss of investee for the year ended December 31, 1996 represents SDL's
net loss for that period. For the year ended December 31, 1997, the
provision for income taxes was a benefit of $2,605,000 versus an
expense of $1,016,000 in the prior year. The benefit is due to the
reversal of $2,800,000 of the deferred tax asset valuation reserve for
net operating loss carryforwards in the United States, which is the
portion of the deferred tax asset that management expects to realize.

Year ended December 31, 1996 compared to year ended December 31, 1995
- ---------------------------------------------------------------------

     Revenues for the year ended December 31, 1996 increased to
$100,851,000 over the previous year's revenues of $92,394,000. This
increase is mainly due to a $7,487,000 net increase in product sales
as a result of the newly-acquired Innogenetics' product line, growth
of sales in Eastern Europe, South America and South East Asia as well
as the acquisition of the Company's Canadian distributor. The net
increase in product sales represents an actual increase using a
constant currency basis of $8,836,000 which was partially offset by a
negative foreign exchange impact of $1,349,000. License fees and
royalties revenues increased to $970,000 from $0 in the previous year,
primarily as a result of Abbott exceeding the minimum royalty level as
defined in the 1994 agreement.

     Gross profit on product sales was 65.1% and 67.3% for the years
ended December 31, 1996 and 1995, respectively. Cost of products grew
$4,706,000 as a result of increased sales, increased use of direct
distributors, especially for the newly-acquired Innogenetics'
products, and increased sales of purchased-in products which have
lower gross profit margins. Furthermore, the strengthening of the
British Pound relative to the U.S. Dollar throughout 1996 caused the
translated Dollar equivalent cost of manufacturing in the U.K. to
increase.

     Total operating costs and expenses, excluding cost of products
sold, of $62,538,000 for the year ended December 31, 1996 reflect a
net decrease of $3,553,000 over the year ended December 31, 1995.
Research and development costs for 1996 were reduced by $1,057,000 due
to added efficiencies in internal costs and the Company shifting its
focus to forming strategic business alliances such as with
Innogenetics. General and administrative expenses increased $1,385,000
to $25,803,000 for 1996 as compared to $24,418,000 for 1995. This
increase is due to the legal, employee compensation and other expenses
associated with settling the Company's HCV patent litigation during
the third quarter of 1996. Sales and marketing expenses were
$29,523,000 and $26,898,000 for the years ended December 31, 1996 and
1995, respectively. The increase of $2,625,000 was driven by new
product introductions, including the Innogenetics' LiPA product line,
expansion into the monitoring market and further strengthening of the
Company's overall distribution network. The foreign exchange loss for
the year ended December 31, 1996 was $1,542,000 versus a gain of
$1,016,000 for 1995. The loss is primarily attributable to the
strengthening of the British Pound to its then four year high, as MBL
(the Dartford, England manufacturing facility) carried intercompany
receivables in the local currencies of the various Murex Group
territories. This foreign exchange loss was further exacerbated by the
weakening of the South African Rand. As a result of the 1996 agreement
with Chiron and Ortho, a reversal was made to royalty accruals made in
prior years, which resulted in a net credit to royalty expense of
$2,799,000 for the year ended December 31, 1996. During September
1996, the Company recorded a restructuring charge of $2,100,000 before
tax. The restructuring was driven by a need to reposition the Company
for its movement into the patient monitoring business. The world-wide
plan resulted in personnel reductions from various functions. The
restructuring charge consists predominantly of costs for employee
severance and other benefits, of which $1,402,000 remained accrued at
December 31, 1996.

     Net interest expense for the year ended December 31, 1996 was
$643,000 compared to net interest income of $1,054,000 for the year
ended December 31, 1995 due to the increase in long term debt from the
new line of credit arrangement and the factoring of Italian
receivables. The loss on liquidation of investee of $394,000
represents SDL's net loss for the year ended December 31, 1996, net of
the estimated gain upon ultimate liquidation. As of December 31, 1996,
IMTC and its subsidiaries represented predominantly all creditors of
SDL; therefore, in the financial statements, the subsidiary is assumed
to be fully liquidated.








<PAGE>



ITEM 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA


International Murex Technologies Corporation
CONSOLIDATED BALANCE SHEETS

                                                                  December 31,
                                                               -----------------
(In Thousands of U. S. Dollars)                                  1997      1996
- --------------------------------------------------------------------------------


ASSETS

CURRENT ASSETS
    Cash and cash equivalents                                  $10,087   $ 9,723
    Accounts receivable, net of allowance for doubtful
      accounts of $2,939 and $3,174,  respectively              35,062    33,718
    Inventories                                                 21,164    21,534
    Amounts due from affiliates                                  1,477     4,415
    Prepaid and other                                            3,454     1,207
                                                               -----------------

Total current assets                                            71,244    70,597
- --------------------------------------------------------------------------------

PROPERTY, PLANT AND EQUIPMENT-
    at cost less accumulated depreciation and amortization      13,245    10,091

PATENTS, TRADEMARKS AND LICENSES-
    at cost less accumulated amortization                        7,016     5,738

OTHER ASSETS                                                     3,738     8,687
                                                               -----------------

TOTAL                                                          $95,243   $95,113
================================================================================


See notes to consolidated financial statements.




                                       17

<PAGE>



                                                                December 31,
                                                          --------------------
                                                              1997       1996
- ------------------------------------------------------------------------------

LIABILITIES AND SHAREHOLDERS' EQUITY

CURRENT LIABILITIES
    Trade accounts payable                                 $ 10,215    $  9,757
    Accrued expenses:
          Professional fees                                   1,229       2,222
          Royalty payments                                    1,559       1,978
          Employee related                                    5,032       5,985
          Income taxes payable                                  827       1,508
          Litigation settlements                                155       3,310
          Restructuring                                                   1,402
          Other                                               3,110       2,809
    Current portion of long term debt                            95
    Current portion of capitalized lease obligations            163         151
                                                           --------------------

Total current liabilities                                    22,385      29,122
- -------------------------------------------------------------------------------

DEFERRED RENT                                                    47          77

LONG TERM DEBT,  less current portion                        14,331       9,638

CAPITALIZED LEASE OBLIGATIONS, less current portion             248          93

COMMITMENTS AND CONTINGENCIES

SHAREHOLDERS' EQUITY
Common shares, without par value,
     200,000,000 shares authorized;  16,689,934 and
      16,578,853 shares issued, respectively                 84,780      84,460
Additional paid-in capital                                   14,521      13,906
Accumulated deficit                                         (32,591)    (41,655)
Less cost of  101,043 and 286,929
  common shares held in treasury, respectively                   (5)     (1,085)
Unrealized gain on marketable securities                        676       4,405
Accumulated currency translation adjustment                  (9,149)     (3,848)
                                                           --------------------

Shareholders' equity                                         58,232      56,183
- -------------------------------------------------------------------------------

TOTAL                                                      $ 95,243    $ 95,113
===============================================================================


See notes to consolidated financial statements.




                                       18

<PAGE>




<PAGE>




Second Page for Balance Sheet




<PAGE>



International Murex Technologies Corporation
CONSOLIDATED STATEMENTS OF OPERATIONS



                                                Year Ended December 31,
                                         -----------------------------------
(In Thousands of U.S. Dollars,
except per share data)                    1997          1996         1995
- ----------------------------------------------------------------------------

REVENUES
   Product sales                         $  98,553    $  99,881    $  92,394
   License fees and other (See Note 6)       7,579          970
                                         -----------------------------------
Total revenues                             106,132      100,851       92,394

COSTS AND EXPENSES
   Cost of products sold                    39,250       34,887       30,181
   Research and development                  7,487        6,369        7,426
   General and administrative               21,630       25,803       27,541
   Sales and marketing                      28,883       29,523       26,898
   Foreign exchange loss (gain)                104        1,542       (1,016)
   Royalty expense (credit)                  5,625       (2,799)       8,365
   Restructuring expense                                  2,100
                                         -----------------------------------
Total costs and expenses                   102,979       97,425       99,395
- ----------------------------------------------------------------------------
INCOME (LOSS) FROM OPERATIONS                3,153        3,426       (7,001)

Interest income                                290          663        1,221
Interest (expense)                          (1,422)      (1,306)        (167)
Gain (loss) on asset disposals                 (50)          90          108
Gain (loss) on liquidation of investee       1,114         (394)
Other income (expense)                       3,374          386         (289)
                                         -----------------------------------
INCOME (LOSS) BEFORE INCOME TAXES            6,459        2,865       (6,128)

Income tax benefit (expense)                 2,605       (1,016)        (482)
                                         -----------------------------------
NET INCOME (LOSS)                        $   9,064    $   1,849    $  (6,610)
============================================================================

NET INCOME (LOSS) PER COMMON SHARE
   Basic                                 $    0.55    $    0.11    $   (0.40)
                                         =========    =========    ========= 
   Diluted                               $    0.52    $    0.11    $   (0.40)
                                         =========    =========    ========= 



WEIGHTED AVERAGE SHARES OUTSTANDING
   Basic, in thousands                      16,484       16,215       16,381
                                         =========    =========    =========
   Diluted, in thousands                    17,444       16,507       16,381
                                         =========    =========    =========



See notes to consolidated financial statements.



                                  19
<PAGE>  




<PAGE>



International Murex Technologies Corporation
CONSOLIDATED STATEMENTS OF CHANGES IN SHAREHOLDERS' EQUITY

(In Thousands of U.S. Dollars, except share data)
<TABLE>
<CAPTION>

- ------------------------------------------------------------------------------------------------------------------------------------


                                           Common Stock         Additional
                                      -----------------------    Paid-In   Accumulated
                                        Shares       Amount      Capital     Deficit
- -------------------------------------------------------------------------------------
<S>                                   <C>          <C>         <C>         <C>

January 1, 1995                       16,778,646  $   84,082   $  13,906   $  (36,894)

Issued pursuant to employee
  stock purchase plan                     17,375          54

Shares repurchased for treasury

Retirement of  escrowed shares          (107,144)

Issued in exchange for
  subsidiary shares                           54

Net loss                                                                       (6,610)

Foreign currency translation
                                      -----------------------------------------------

December 31, 1995                     16,688,931      84,136      13,906      (43,504)

Issued pursuant to employee
  stock purchase plan                     23,297          91

Exercise of employee stock options        15,900          50

Issued as stock compensation             281,925       1,692

Shares tendered to treasury

Retirement of treasury shares           (431,200)     (1,509)

Unrealized gain on marketable
   securities

Net income                                                                      1,849

Foreign currency translation
                                      -----------------------------------------------

December 31, 1996                     16,578,853      84,460      13,906      (41,655)

Issued pursuant to employee
  stock purchase plan                     23,617         155

Exercise of employee stock options       218,300         999

Retirement of treasury shares           (185,886)     (1,080)

Issued pursuant to class action
   settlement                             80,120         465

Reversion of settlement shares                                       615

Shares tendered as tax withholding       (25,070)       (219)

Net change in unrealized gain on
   marketable securities

Net income                                                                      9,064

Foreign currency translation
                                      ===============================================

December 31, 1997                     16,689,934  $   84,780   $  14,521   $  (32,591)
                                      ===============================================
</TABLE>



<TABLE>
<CAPTION>
- ------------------------------------------------------------------------------------------
                                                  Unrealized   Accumulated
                                                   Gain on      Currency       Total
                                     Treasury    Marketable    Translation   Shareholders'
                                       Shares     Securities   Adjustment      Equity
- ------------------------------------------------------------------------------------------
<S>                                    <C>         <C>        <C>             <C>

January 1, 1995                        $     (5)              $   (4,585)  $   56,504

Issued pursuant to employee
  stock purchase plan                                                              54

Shares repurchased for treasury          (1,509)                               (1,509)

Retirement of  escrowed shares

Issued in exchange for
  subsidiary shares

Net loss                                                                       (6,610)

Foreign currency translation                                       1,092        1,092
                                      ------------------------------------------------

December 31, 1995                        (1,514)                  (3,493)      49,531

Issued pursuant to employee
  stock purchase plan                                                              91

Exercise of employee stock options                                                 50

Issued as stock compensation                                                    1,692

Shares tendered to treasury              (1,080)                               (1,080)

Retirement of treasury shares             1,509

Unrealized gain on marketable
   securities                                     $    4,405                    4,405

Net income                                                                      1,849

Foreign currency translation                                        (355)        (355)
                                      ------------------------------------------------

December 31, 1996                        (1,085)       4,405      (3,848)      56,183

Issued pursuant to employee
  stock purchase plan                                                             155

Exercise of employee stock options                                                999

Retirement of treasury shares             1,080

Issued pursuant to class action
   settlement                                                                     465

Reversion of settlement shares                                                    615

Shares tendered as tax withholding                                               (219)

Net change in unrealized gain on
   marketable securities                              (3,729)                  (3,729)

Net income                                                                      9,064

Foreign currency translation                                      (5,301)      (5,301)
                                      ===============================================

December 31, 1997                      $     (5)  $      676  $   (9,149)  $   58,232
                                      ================================================

</TABLE>




See notes to consolidated financial statements.


                                  20
<PAGE>




<PAGE>



International Murex Technologies Corporation
CONSOLIDATED STATEMENTS OF CASH FLOWS
<TABLE>
<CAPTION>

                                                                    Year Ended December 31,
                                                              --------------------------------
(In Thousands of U.S. Dollars)                                   1997        1996       1995
- ----------------------------------------------------------------------------------------------
<S>                                                           <C>          <C>          <C>

OPERATING ACTIVITIES:
Net  income (loss)                                            $  9,064    $  1,849    $ (6,610)
Adjustments to reconcile net income (loss) to net
    cash provided by (used in) operating activities:
              Depreciation                                       3,903       3,519       4,199
              Amortization                                         850         459          85
              Loss (gain) on sale of property and equipment         50         (90)       (108)
              Gain on sale of marketable securities             (3,095)
              Deferred taxes                                    (2,800)
              Non-cash compensation                              2,694       1,692
              Changes in assets and liabilities:
                     Accounts receivable                         1,885       1,118      (3,074)
                     Inventories                                   370      (4,593)     (1,154)
                     Prepaid and other assets                   (1,004)     (1,088)      1,388
                     Trade accounts payable                        458       2,171       1,999
                     Accrued expenses                           (6,365)     (9,963)      5,444
- ----------------------------------------------------------------------------------------------
       Net cash (used in) provided by operating activities       6,010      (4,926)      2,169
- ----------------------------------------------------------------------------------------------

INVESTING ACTIVITIES:
Proceeds from sale of property and equipment                       157         269         265
Additions to property and equipment                             (7,805)     (4,558)     (4,994)
Additions to patents and licenses                               (2,128)     (5,968)       (101)
Proceeds from sale of marketable securities                      2,811
- -----------------------------------------------------------------------------------------------
      Net cash used in investing activities                     (6,965)    (10,257)     (4,830)
- -----------------------------------------------------------------------------------------------

FINANCING ACTIVITIES:
Increase in borrowings under line of credit                      3,263       9,638          40
Increase (decrease) of other long-term liabilities               1,342        (289)       (458)
Proceeds from issuance of common shares                          1,154         141          54
Repurchase of shares for treasury                                                       (1,509)
- -----------------------------------------------------------------------------------------------
     Net cash provided by (used in) financing activities         5,759       9,490      (1,873)
- -----------------------------------------------------------------------------------------------

Effect of Exchange Rate Changes                                 (4,440)       (355)      1,092

Net Increase (Decrease) in Cash and Cash Equivalents               364      (6,048)     (3,442)

Cash and Cash Equivalents at Beginning of Period                 9,723      15,771      19,213
- -----------------------------------------------------------------------------------------------
CASH AND CASH EQUIVALENTS AT END OF PERIOD                    $ 10,087    $  9,723    $ 15,771
- -----------------------------------------------------------------------------------------------

Supplemental Disclosure of Cash Flow Information:
       Cash paid for interest                                 $  1,238    $  1,306    $    148
       Cash paid for income taxes                             $    876    $  1,140    $  1,348


</TABLE>



                                  21
<PAGE>




<PAGE>



International Murex Technologies Corporation
- --------------------------------------------
CONSOLIDATED STATEMENTS OF CASH FLOWS (CONTINUED)
(In Thousands of U.S. Dollars)
- ------------------------------

SUPPLEMENTAL DISCLOSURE OF NONCASH INVESTING AND FINANCING ACTIVITIES:

     During the years ended December 31, 1997, 1996 and 1995, the
Company entered into capital lease obligations of approximately $320,
$63 and $53 respectively.

    Unpaid acquisition costs totaled $750 at December 31, 1995.

See notes to consolidated financial statements.




<PAGE>



International Murex Technologies Corporation
- --------------------------------------------
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

(In Thousands of U.S. Dollars, except share amounts)
- ----------------------------------------------------


- --------------------------------------------------------------------------------

1.   NATURE OF THE COMPANY AND BASIS OF PRESENTATION:

     International Murex Technologies Corporation ("IMTC"), is
     incorporated in Canada and has many incorporated subsidiaries
     operating throughout the world under the Murex name (the "Murex
     Group"). The Murex Group develops, manufactures and markets
     medical diagnostic products and provides medical services for the
     screening, diagnosis and monitoring of infectious diseases and
     other medical conditions. (IMTC and the Murex Group are
     collectively referred to herein for consolidated financial
     purposes only as the "Company".)

     The accompanying financial statements include IMTC and its
     wholly-owned, incorporated subsidiaries doing business in various
     territories generally under the name Murex Diagnostics, Murex
     Holdings Corporation ("MHC"), a Delaware corporation; and MHC's
     majority owned subsidiary; Murex Corporation ("Murex"), a
     Delaware corporation; and Murex's wholly owned subsidiaries. In
     August 1995, Murex, a then majority-owned subsidiary was merged
     with MHC and subsequently into Murex Diagnostics, Inc. ("MDI").
     The previous minority interest's portion of Murex's continued
     losses in excess of their basis has not been recorded because
     management considers that it is not currently realizable. At
     December 31, 1996, the U.S. subsidiaries were further
     consolidated by merging the U.S. holding company, IMTC Holdings,
     Inc. into MDI.

     Effective January 1, 1996, IMTC's U.K. operating business was
     restructured into two companies, Murex Diagnostics Limited
     ("MDL") and Murex Biotech Limited ("MBL"). MDL subsequently
     changed its name to Specialist Diagnostics Limited ("SDL") and
     entered voluntary liquidation. As of December 31, 1997 and 1996,
     IMTC and its subsidiaries represented predominately all of the
     creditors of SDL; therefore, in the consolidated financial
     statements, the subsidiary is assumed to be fully liquidated.
     During 1997, approximately $3,888 in cash was returned to the
     Company from the SDL liquidator. During the fourth quarter of
     1997, claims with various tax authorities including Inland
     Revenue were effectively settled which resulted in additional
     expected proceeds of $1,114. As such, management expects to
     receive the remaining net proceeds of $1,477 from the SDL
     liquidator after settlement of all liquidation costs, which is
     reflected as of December 31, 1997 as amounts due from affiliates.

2.   SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES:

     The Company's financial statements have been prepared in
     accordance with United States generally accepted accounting
     principles and reflect the following policies:

     (A)  BASIS OF CONSOLIDATION: The consolidated financial
          statements include the accounts of IMTC and all
          subsidiaries. All significant intercompany accounts and
          transactions are eliminated.

     (B)  CASH EQUIVALENTS: The Company considers all highly liquid
          investments with original maturities of three months or less
          to be cash equivalents.

     (C)  ACCOUNTS RECEIVABLE: Accounts receivable include amounts due
          from customers in Italy and Spain which, if not factored,
          may take approximately one year to collect. An allowance for
          estimated doubtful accounts is provided, as considered
          appropriate, based on identification of specific
          uncollectible receivables.

     (D)  INVENTORIES: Stated at the lower of cost (first-in,
          first-out method) or market.

     (E)  LONG-LIVED ASSETS: At each balance sheet date management
          reviews assets for impairment based on its expectations of
          future non-discounted cash flows. Based on the Company's
          most recent analysis, the Company believes no material
          impairment of assets exists at December 31, 1997.

     (F)  PROPERTY, PLANT AND EQUIPMENT: Stated at cost less
          accumulated depreciation. Depreciation is provided by the
          straight-line method over the useful lives of the assets:
          forty years for buildings, three to ten years for equipment
          and furniture, and the lesser of the useful life or the term
          of the lease for leasehold improvements.

     (G)  PATENTS, TRADEMARKS AND LICENSES: Costs incurred for legal
          expenses in connection with obtaining patent protection,
          trademark rights and licenses for certain technology have
          been deferred. Amortization of such costs is provided by the
          straight-line method over five years for patents and
          trademarks and over the life of the agreement, not to exceed
          seven years, for license agreements.

     (H)  INVESTMENTS: The Company accounts for its long-term
          investment in the marketable securities of Digene
          Corporation in accordance with Statement of Financial
          Accounting Standards No. 115 ("SFAS 115"), "Accounting for
          Certain Investments in Debt and Equity Securities" .

     (I)  INCOME TAXES: Deferred income taxes are determined in
          accordance with Statement of Financial Accounting Standards
          No. 109 ("SFAS No. 109") and reflect the net tax effects of
          (a) temporary differences between the carrying amounts of
          assets and liabilities for financial reporting purposes and
          the amounts used for income tax purposes, and (b) operating
          loss and tax credit carry forwards.

     (J)  REVENUE: Revenue is recognized at the time product is
          shipped or when contract services are rendered .

     (K)  RESEARCH AND DEVELOPMENT: Research and development costs
          include primarily salaries and benefits, rent, laboratory
          materials and supplies, consulting fees, and subcontract
          costs, and are expensed in the period incurred.

     (L)  FOREIGN EXCHANGE: The reporting currency for the Company is
          the U.S. Dollar. The functional currency for all operations
          is the respective local currency. The translation of all
          foreign currencies into U.S. Dollars is performed for asset
          and liability accounts using exchange rates in effect at the
          balance sheet date, for equity accounts at historical rates,
          and for revenue and expense accounts using a weighted
          average exchange rate during the period. Gains and losses
          resulting from the translation of subsidiary financial
          statements and intercompany foreign currency transactions
          that are of a long-term investment nature are classified as
          accumulated currency translation adjustments within
          shareholders' equity. The gains and losses relating to all
          other transactions have been included in the consolidated
          statements of operations.

     (M)  STOCK BASED COMPENSATION: Accounting for stock options
          issued to employees and non-employee directors is based upon
          the "intrinsic value" method set forth in Accounting
          Principles Board Opinion No. 25 ("APB 25"), "Accountin g for
          Stock Issued to Employees" . Accounting for stock options
          issued to non-employees prior to December 16, 1995 is also
          based upon APB 25. Accounting for stock options issued to
          non-employees (excluding non-employee directors) after
          December 15, 1995 is based upon the "fair value" method set
          forth in Statement of Financial Accounting Standards No. 123
          ("SFAS 123"), "Accountin g for Stock- Based Compensati on".
          See footnote 12 for further discussion of SFAS 123.

     (N)  NET INCOME (LOSS) PER COMMON SHARE: Basic earnings per
          common share are computed by dividing net earnings by the
          weighted average number of common shares outstanding during
          each year. Diluted earnings per share include common share
          equivalents, the incremental shares that would have been
          outstanding upon the assumed exercise of dilutive stock
          options and warrants. For 1995, the calculation of loss per
          common share excludes the effect of common share equivalents
          as such effect is anti-dilutive.

     (O)  PERVASIVENESS OF ESTIMATES: The preparation of financial
          statements in conformity with generally accepted accounting
          principles requires management to make estimates and
          assumption s that affect the reported amounts of assets and
          liabilitie s and disclosure of contingent assets and
          liabilitie s at the date of the financial statements and the
          reported amounts of revenues and expenses during the
          reporting period. Actual results could differ from those
          estimates.

     (P)  RECLASSIFICATIONS: Certain reclassifications of prior year
          amounts have been made to conform to the current year
          financial statement reporting format.

     (Q)  NEW ACCOUNTING PRONOUNCEMENTS: In June 1997, the Financial
          Accounting Standards Board ("FASB") issued SFAS 130,
          "Reporting Comprehens ive Income" and 131, "Disclosur es
          about Segments of an Enterprise and Related Informatio n."
          SFAS 130 establishe s standards for reporting and display of
          comprehens ive income and its components (revenues,
          expenses, gains, and losses) in a full set of general
          purpose financial statements . SFAS 131 establishe s
          standards for, among other things, reporting informatio n
          about operating segments in annual financial statements and
          requires that those enterprise s report selected informatio
          n about operating segments in interim financial reports
          issued to shareholde rs. SFAS 130 and 131 are effective for
          financial statements issued for periods beginning after
          December 15, 1997. Management believes that the adoption of
          these statements will not have a material adverse effect on
          the Company's consolidat ed financial statements .

3.   EQUITY INVESTMENT IN DIGENE CORPORATION:

     IMTC's subsidiary, Murex Diagnostics Corporation ("MDC"), owns
     common shares of Digene Corporation ("Digene"). In accordance
     with the provisions of SFAS 115, the Company has classified the
     investment as "available for sale" and reported it at fair value
     in the Other Assets section of the balance sheet, with the
     unrealized gain credited to a separate component of shareholders'
     equity. At December 31, 1997 and 1996, the fair market value of
     the investment was $1,359 and $7,497, respectively, with
     unrealized holding gains of $676 and $4,405, respectively. During
     the year ended December 31, 1997, 301,475 shares were used to
     settle a compensation liability to management. The Company
     realized a gain of $3,095 upon the disposition of shares during
     1997, which is included in the Other Income section of the income
     statement.

4.  INVENTORIES:
                                          December 31,       December 31,
                                              1997              1996
                                          ------------       ------------
Raw materials and supplies                   $  5,355        $  5,911
Work in process                                10,659          10,734
Finished goods                                  9,909          10,379
                                             --------        --------
Total Inventories                              25,923          27,024
Less inventory reserves                        (4,759)         (5,490)
                                             --------        --------
Total Inventories, net                       $ 21,164        $ 21,534
                                             ========        ========

5.  PROPERTY, PLANT AND EQUIPMENT:
                                          December 31,       December 31,
                                              1997              1996
                                          ------------       ------------
Furniture and office equipment               $  8,725        $  8,585
Equipment                                      18,478          16,524
Leasehold improvements                          2,671           2,316
                                             --------        --------
Total                                          29,874          27,425
Less accumulated depreciation and
amortization                                  (16,629)        (17,334)
                                             --------        --------
Property, plant and equipment, net           $ 13,245        $ 10,091
                                             ========        ========

6.   TECHNOLOGY LICENSING AND OTHER AGREEMENTS:

     MDC completed a non-exclusive, out-licensing transaction during
     1994 by licensing technology to Abbott Laboratories. This
     transaction provided MDC with a $10,000 minimum license fee which
     was paid over four years. Furthermore, MDC earned an additional
     $1,075, $878 and $100 in 1997, 1996, and 1995, respectively, as a
     result of minimum royalty levels being exceeded. Licenses have
     also been granted for SAM(TM) technology to Chiron Corporation
     ("Chiron"). MDC also licenses technology and products from other
     diagnostics manufacturers and generally, the Murex Group pays a
     royalty to these companies based on its sales of the products.
     See Note 15.

     MDC earned an additional $6,504 during 1997 as a result of
     strategic alliance transactions with Digene and Shield
     Diagnostics Group plc ("Shield"). Effective February 1997, the
     Murex Group and Digene entered into a five year distribution,
     agency and sales representation agreement whereby Digene will
     sell its Hybrid Capture (R) human papillomavirus ("HPV") DNA test
     directly in selected European markets using the Company's
     existing distribution infrastructure in exchange for selling
     service fees. Additionally, Digene purchased certain intangible
     properties for cash paid during 1997 and notes which are payable
     through 1998. During June 1997, the Murex Group sold TTP
     Corporation ("TTP"), a wholly-owned subsidiary of MDC, to Shield.
     TTP owned the intellectual property and other rights to ten
     products used for the diagnosis of thyroid dysfunction and the
     measurement of cardiovascular/blood coagulation degradation
     products. The Murex Group will continue to manufacture and sell
     the TTP product line acquired by Shield for a period of three
     years, pursuant to a purchase commitment.

     7.   PATENTS, TRADEMARKS AND LICENSES:

                                          December 31,       December 31,
                                              1997              1996
                                          ------------       ------------

Patents                                      $   891          $   663
Trademarks                                       203              159
Licenses                                       8,096            6,240
                                             -------          -------
Total                                          9,190            7,062
Less accumulated amortization                 (2,174)          (1,324)
                                             -------          -------
Total, net                                   $ 7,016          $ 5,738
                                             =======          =======

8.   BORROWINGS UNDER LINES OF CREDIT:

     On November 12, 1996, the Company entered into a three year,
     $15,000 line of credit facility with Bank of America, which is
     collateralized by the accounts receivable and inventory of its
     U.S., U.K. and Barbados subsidiaries. The credit agreement
     requires the Company to maintain certain financial ratios and
     other financial conditions, prohibits the payment of any IMTC
     dividends except those paid in common shares, and limits capital
     expenditures, certain investments and additional indebtedness. At
     December 31, 1997 and 1996, the Company was in compliance with
     all loan covenants. Based on the value of the collateral, the
     borrowings outstanding of $12,996 and a letter of credit
     outstanding of $825, there was $186 unused and available under
     this credit facility as of December 31, 1997. Interest is payable
     monthly at either LIBOR (5.7% at December 31, 1997) plus 2.5% or
     prime (8.5% at December 31, 1997).

     On December 11, 1996, the Company entered into a five year,
     interest rate swap agreement to reduce the impact of changes in
     interest rates on its LIBOR-based line of credit. The five year
     agreement effectively fixed the total interest rate at 8.9%, on a
     notional principal amount of $8,000. The Company specifically
     designated this interest rate swap agreement as a hedge of the
     line of credit, and therefore recognizes the differential paid or
     received as an adjustment to interest expense in the period in
     which it occurs. Therefore, as of December 31, 1997 and 1996,
     there were no carrying amounts related to the interest rate swap
     agreement in the consolidated balance sheets. The estimated fair
     value of the interest rate swap agreement, based on current
     market rates approximated a payable of $122 and $0 at December
     31, 1997 and 1996, respectively. The Company is exposed to credit
     loss in the event of non-performance in the event the other party
     to the interest rate swap agreement, however the Company does not
     anticipate non-performance by the counter party. See also
     Footnote 20.

     In order to finance a new manufacturing facility in South Africa
     as well as provide a partial, natural foreign exchange hedge of
     its long term investment, the Company entered into a Rand
     denominated six year term loan with a capacity of approximately
     $1,600 at an interest rate of 10.5%. The interest rate is
     favorable by South African standards because the loan is part of
     an investment incentive package which includes a tax holiday. At
     December 31, 1997, $1,430 was outstanding under this term loan,
     which is collateralized by the property in South Africa and
     guaranteed by IMTC.

     The scheduled maturities of long term debt are as follows:

     1998                                  $    95
     1999                                   13,282
     2000                                      286
     2001                                      286
     2002                                      286
     Thereafter                                191
                                            ------
     Total                                 $14,426
                                           =======


     The weighted average interest rate on average outstanding debt
     was 9.17%, 8.89% and 9.66% for each of the years ended December
     31, 1997, 1996 and 1995, respectively.

9.   CAPITAL LEASES:

     Capitalized lease obligations for property and equipment bear
     interest at an imputed average rate of 8.08%. The leases are
     collateralized by equipment with an original cost of $792 and
     $689 and a net book value of $257 and $81 at December 31, 1997
     and 1996, respectively. Future minimum lease payments under
     capital leases with terms in excess of one year at December 31,
     1997, together with the present value of minimum lease payments,
     are shown in the table below.

     1998                                  $   194
     1999                                      188
     2000                                      109
     2001                                        3
                                           -------
     Total                                     494
     Less interest                             (83)
                                           -------
     Present value                             411
     Current portion                          (163)
                                           -------
     Long term                             $   248
                                           =======

10.  OPERATING LEASES:

     The Company leases office space and certain office equipment
     under operating lease agreements. Future minimum lease payments
     under noncancellable operating lease agreements with terms in
     excess of one year are as follows:

     1998                                  $ 3,549
     1999                                    3,109
     2000                                    1,462
     2001                                      951
     2002                                      743
     Thereafter                                125
                                           -------
     Total                                 $ 9,939
                                           =======

     Rent expense under all operating leases amounted to approximately
     $3,179, $1,776 and $1,711 for each of the years ended December
     31, 1997, 1996 and 1995, respectively.


11.  INCOME TAXES:

     The taxation of a company that has operations in several
     countries involves many complex variables, such as differing tax
     structures from country to country as well as the existence and
     use of operating loss carryforwards in certain tax jurisdictions.
     These complexities do not permit meaningful comparisons between
     the domestic and international components of income before taxes
     and the provision for income taxes, and disclosures of these
     components do not provide indicators of relationships in future
     periods.

     The Company's deferred tax assets are subject to a valuation
     allowance that reduces the deferred tax assets at December 31,
     1997 and 1996 to $2,800 and $0, respectively. The long-term
     portions of the deferred tax assets were $1,435 and $0 at
     December 31, 1997 and 1996, respectively. The tax effects of
     significant items comprising the Company's deferred taxes are as
     follows:


                                          December 31,       December 31,
                                              1997              1996
                                          ------------       ------------

Deferred tax liabilities:
      Asset basis differences                $    91         $     22
                                            --------         --------

Deferred tax assets:
      Book reserves                            1,231            2,574
      Operating loss carryforwards            15,032           12,378
      All other                                  761            3,040
                                            --------         --------
                                              17,024           17,992
Less: Valuation allowance                    (14,133)         (17,970)
                                            --------         --------
                                               2,891               22
                                            --------         --------
Deferred income taxes                        $ 2,800         $      0
                                            ========         ========
                                                        
     During 1996, the Company increased the beginning balance of the
     valuation allowance by $1,810 to reflect the liquidation of SDL.

     The components of earnings and income tax expense (benefit) are
     as follows:

     Earnings (losses) before income taxes:

                                 1997            1996          1995
                                 ----            ----          ----
U.S.                           $ 2,205        $ 1,964         $   505
Foreign                          4,254            901          (6,633)
                               -------        -------         -------
                               $ 6,459        $ 2,865         $(6,128)
                               =======        =======         =======






Income Tax Provision              1997            1996           1995
                                  ----            ----           ----
Current
    Federal                     $    52         $    35        $    11

    State                            45              31             45
    Foreign                          98             835            423
Deferred
    Federal                      (2,800)
    Foreign                                         115              3
                                -------         -------        -------
    Total                       $(2,605)        $ 1,016        $   482
                                =======         =======        =======

     A reconciliation of differences between the statutory U.S.
     federal income tax rate and the Company's effective rate is as
     follows:

                                          1997       1996      1995
                                          ----       ----      ----

U.S.  Statutory Rate                    $ 2,196    $   974    $(2,084)
State taxes                                 258        115       (125)
Increase (decrease) in valuation
allowance                                (3,873)     2,497       (252)
Increase in unused net operating
losses                                    2,654        243      4,349
Effect of foreign rates differing
from U.S. statutory rate                 (3,840)    (2,813)    (1,406)
                                        -------    -------    -------
Total                                   $(2,605)   $ 1,016    $   482
                                        =======    =======    =======


     At December 31, 1997 the Company had, for tax reporting purposes,
     net operating loss carryforwards of approximately $41,824,
     generated as follows:

                                                          Other
                          U.S.      Canada      U.K.      Foreign     Total
                          ----      ------      ----      -------     -----

     1997                          $   975    $ 3,483    $ 4,734    $ 9,192
     1996                            1,200      2,876      1,938      6,014
     1995                              675                   362      1,037
     1994               $   724                              369      1,093
     1993                 1,076        290                   921      2,287
     Prior periods       18,868      3,333                           22,201
                        -------    -------    -------    -------    -------
     Total              $20,668    $ 6,473    $ 6,359    $ 8,324    $41,824
                        =======    =======    =======    =======    =======

     The company has recorded a deferred tax asset of $2,800
     reflecting the benefit of $7,368 in U.S. loss carryforwards,
     which expire in varying amounts between 1999 and 2009.
     Realization is dependent on generating sufficient taxable income
     prior to expiration of the loss carryforwards. Although
     realization is not assured, management believes it is more likely
     than not that all of the deferred tax asset will be realized. The
     amount of the deferred tax asset considered realizable, however,
     could be reduced in the near term if estimates of future taxable
     income during the carryforward period are reduced.

     The carryforwards expire through 2004 for Canadian purposes.
     Other foreign jurisdiction tax loss carryforwards include
     European countries which generally expire in 1998 or have
     indefinite carryforwards. The 1997, 1996 and 1995 income tax
     provisions primarily represent current amounts due to various
     U.S. state taxing authorities and various foreign taxing
     authorities.

     The net operating losses include the U.S. net operating losses of
     Murex prior to the merger of Murex into MDI. Net operating loss
     carryforwards for income tax purposes of $9,850 are subject to an
     annual limitation of approximately $390 on utilization due to a
     change in ownership in June 1988. As of December 31, 1997, $6,145
     was not yet available for utilization.

12.  COMMON SHARES:

     (A)  NET INCOME (LOSS) PER COMMON SHARE: In February 1997, the
          Financial Accounting Standards Board issued Statement of
          Financial Standards No. 128, "Earnings Per Share" ("SFAS
          128"). SFAS 128 requires disclosure of basic earnings per
          common share based on the net income (loss) and the weighted
          average number of common shares outstanding during the
          period. SFAS 128 also requires disclosure of diluted
          earnings per common share based on the net income (loss) and
          the weighted average number of common shares and common
          share equivalents outstanding during the period. All periods
          presented are retroactively restated to conform to the
          presentation requirements of SFAS 128. The following table
          represents the computation of basic and diluted earnings per
          common share:

<TABLE>
<CAPTION>

                                                           1997      1996        1995
                                                           ----      ----        ----
      <S>                                               <C>         <C>         <C>

     Basic earnings per common share:
           Net income (loss)                            $  9,064   $  1,849   $ (6,610)
           Weighted average common shares outstanding     16,484     16,215     16,381
           Basic net income (loss) per common share     $   0.55   $   0.11   $  (0.40)
     Diluted earnings per common share:
           Net income (loss)                            $  9,064   $  1,849   $ (6,610)
           Weighted average common shares outstanding     16,484     16,215     16,381
           Common stock equivalents                          960        292
                                                        --------   --------   --------
           Total weighted average shares                  17,444     16,507     16,381
           Diluted net income (loss) per common share   $   0.52   $   0.11   $  (0.40)

</TABLE>


     (B)  STOCK OPTIONS: On May 11, 1993, IMTC adopted the
          International Murex Technologies Corporation Employee Equity
          Incentive Plan (the "1993 Plan"), which was approved by
          shareholders in June 1993. The plan was amended and restated
          in June 1994. The number of options issued under this plan
          may not exceed 2 million. The option price per share shall
          be determined by the Compensation Committee at the time any
          option is granted and shall not be less than the closing
          trading price of the stock on the date of grant. Options
          granted to management generally vest at 50% per year over a
          two year period and expire five years from the grant date.
          Options granted to non- employee directors generally vest
          immediately and expire ten years from the grant date. In
          February 1996, the Compensation Committee of IMTC determined
          that certain of the outstanding options no longer provided
          the incentives intended by the original grants and
          authorized replacement of 946,100 of the options
          outstanding. This constituted all of the outstanding options
          except those held by outside directors, terminated employees
          and consultants. Replacement options totaling 946,100 were
          reissued on March 4, 1996 at an exercise price of $3.13 each
          expiring in March 2001.






<PAGE>



     The following table summarizes the stock option activity for the
     three years ended December 31, 1997.


<TABLE>
<CAPTION>

                                       Range of Exercise           Number of            Exercise
                                             Prices                 Options               Price
                                     ----------------------   -------------------   -----------------
<S>                                        <C>                      <C>                <C>

Balance, December 31, 1994                   $5.00 - 7.00             1,694,100           $6.14
Granted                                              3.38                80,000            3.38
Canceled                                      4.20 - 7.00             (123,500)            6.09
                                                              -------------------
Balance, December 31, 1995                    3.38 - 7.00             1,650,600            6.01
Granted                                       3.13 - 6.00             1,390,500            3.24
Canceled                                      3.13 - 7.00           (1,382,100)            6.03
Exercised                                            3.13              (15,900)            3.13
                                                              -------------------
Balance, December 31, 1996                    3.13 - 6.00             1,643,100            3.68
Granted                                       6.44 - 8.88               302,100            7.29
Canceled                                      3.13 - 7.13              (19,250)            4.77
Exercised                                     3.13 - 6.00             (218,300)            4.57
                                                              -------------------
Balance, December 31, 1997                    3.13 - 8.88             1,707,650            4.19
                                                              ===================

</TABLE>

          The weighted average grant date fair value of the options
          granted was $4.17, $1.67 and $2.69 for 1997, 1996 and 1995,
          respectively. At December 31, 1997, 1996 and 1995, the
          number of exercisable options was 1,377,700, 1,338,900 and
          1,677,434, respectively, and the weighted average exercise
          price of those options was $3.91, $3.79 and $6.14,
          respectively.

          The following table summarizes information about stock
          options outstanding and exercisable at December 31, 1997.

<TABLE>
<CAPTION>

                                  Options Outstanding                               Options Exercisable
             -------------------------------------------------------------  -----------------------------------
<S>                <C>                 <C>                   <C>                  <C>                <C>
                                          Weighted
                     Number               average                                 Number            Weighted
  Range of       outstanding at          remaining           Weighted         exercisable at        average
  Exercise        December 31,          contractual          average           December 31,         exercise
   Prices             1997                  life          exercise price           1997              price
- ---------------------------------------------------------------------------------------------------------------
 $3.13 - 4.50           1,169,850           3.4               $3.15                1,027,700         $3.14
  4.51 - 6.00             240,000           6.3                5.42                  230,000          5.40
  6.01 - 7.50             277,800           5.5                7.18                  100,000           7.39

  7.51 - 8.88              20,000            9.0               8.88                   20,000            8.88
             ----------------------                                         ------------------
                        1,707,650           4.2                4.19                1,377,700            3.91
             ======================                                         ==================
</TABLE>


<PAGE>

          The Company has adopted the disclosure only provisions of
          SFAS No. 123, "Accounting for Stock-Based Compensation".
          Accordingly, no compensation cost has been recognized for
          the stock option plans. Had compensation cost for the
          Company's stock option plans been determined based on the
          fair value at the grant date for awards in 1997, 1996 and
          1995, consistent with the provisions of SFAS No. 123, the
          Company's earnings would have been reduced to the pro forma
          amounts indicated below:

<TABLE>
<CAPTION>
                                                       1997        1996         1995
                                                  ---------   ---------    ---------
<S>                                               <C>         <C>          <C>       
Net income (loss) - as reported                   $   9,604   $   1,849    $  (6,610)
Net income (loss) - pro forma                         7,800        (254)      (6,825)
Basic earnings per common share - as reported          0.55        0.11        (0.40)
Basic earnings per common share - pro forma            0.47       (0.02)       (0.42)
Diluted earnings per common share - as reported        0.52        0.11        (0.40)
Diluted earnings per common share - pro forma          0.45       (0.02)       (0.42)

</TABLE>

          The fair value of each option grant is estimated on the date
          of grant using the Black Scholes option-pricing model with
          the following weighted-average assumptions used for grants
          in 1997, 1996 and 1995: dividend yield of 0%; expected
          volatility ranging from 69% to 74%; risk free interest rate
          ranging from 5.3% to 6.7%; and expected lives ranging from
          three to ten years.

     (C)  ISSUANCE OF COMMON SHARE PURCHASE WARRANTS: In February
          1996, IMTC entered into an agreement with an investment
          banking firm. As compensation for its services the
          investment banker received common share purchase warrants to
          purchase an aggregate of 100,000 common shares exercisable
          for a period of two years from February 12, 1996. These
          warrants were issued in two lots of 50,000 with exercise
          prices of $4.50 and $5.50 per share, respectively, and the
          Company recorded an expense of $64 related to these
          warrants. As of December 31, 1997 all of these warrants
          remained outstanding, however, all of the warrants were
          exercised on or before February 11, 1998. 

     (D)  EMPLOYEE STOCK PURCHASE PLAN: On April 14, 1993, IMTC
          adopted the International Murex Technologies Corporation
          Employee Stock Purchase Plan (the "Purchase Plan"), which
          was approved by shareholders in June 1993. Under the
          Purchase Plan, all eligible employees can purchase common
          shares of IMTC's stock at 90% of the closing market price on
          the last day of each month. The number of common shares
          which may be purchased under the plan available to employees
          shall be set from time to time by the Compensation Committee
          and was initially 100,000. On May 13, 1997, the shareholders
          approved an amendment to the Purchase Plan which increased
          the number of shares available by 500,000. Additionally, the
          amendment changed the purchase price to 85% of the lower of
          the fair market value at the beginning or end of a six month
          interval. The new purchase price was incorporated into the
          Purchase Plan effective January 1, 1998.

     (E)  SHARES RESERVED FOR FUTURE ISSUE: At December 31, 1997, IMTC
          has reserved common shares for issuance as shown in the
          table below.

          Options                                  1,851,237
          Employee Stock Purchase Plan               511,135
          Warrant Conversion                         100,000
                                                   ---------
          Total                                    2,462,372
                                                   =========

     (F)  TREASURY SHARES: In November 1996, pursuant to the
          Stipulation Settlement Agreement, Edward J. DeBartolo, Jr.
          and the Estate of Edward J. DeBartolo, Sr. each transferred
          92,943 common shares of the Company's stock to the Company
          to be used as their portion of the settlement of the class
          action lawsuits initiated in 1992. These shares were retired
          during 1997. See Footnote 16.

13.  EMPLOYEE RETIREMENT PLANS:

     The Murex Group has contributory and non-contributory defined
     contribution plans covering substantially all employees. The plan
     funding arrangements are consistent with the United States or
     other applicable governmental laws and regulations. The plans
     provide for employer match up to twice the employee contribution
     percentage to a maximum employer matching contribution of 10%.
     The Murex Group's contributions to these plans amounted to
     approximately $1,777, $1,637 and $1,587 in the years 1997, 1996
     and 1995, respectively.

     Certain of the Murex Group also have defined benefit pension
     plans covering selected employees in certain European locations.
     Pension costs and actuarial data are not significant to the
     consolidated financial statements. The Company currently provides
     no post-retirement benefit plans other than pensions, nor any
     significant post-employment benefits, therefore, the financial
     statements have no such provisions.

14.  FINANCIAL INSTRUMENTS AND CONCENTRATIONS OF CREDIT RISK:

     The Company places its cash and cash equivalents with high credit
     quality financial institutions. As of December 31, 1997, the
     Company had no significant concentrations of credit risk. The
     Company has estimated the fair value of its financial
     instruments, using available market information and appropriate
     valuation methodologies. Considerable judgment is required in
     developing the estimated fair value and therefore the values are
     not necessarily indicative of the amounts that the Company could
     realize in a current market exchange.

15.  COMMITMENTS:

     Certain of the Murex Group also incur royalty obligations on
     certain product sales for the use of patent and license rights.
     Royalty rates may vary depending on particular product sales
     levels. Agreed royalties are payable on defined sales ranging
     from 2% to a combined maximum royalty of 35% for a particular
     product's sales. In addition, the Company also has future minimum
     royalty payments as follows:

     1998                        $1,365
     1999                         1,365
     2000                         1,365
     2001                         1,282
     2002                         1,200
     Thereafter                     600
                                 ------
     Total                       $7,177
                                 ======
    
     During February 1996, MDC entered into an exclusive distribution,
     development and license agreement with Innogenetics to develop
     and market gene probe products for the monitoring of patients and
     the classification of viral diseases. Under the terms of the
     agreement, MDC paid $5,900 during 1996 and $1,600 during 1997 to
     Innogenetics for the exclusive rights to distribute Innogenetics'
     LiPA products, excluding HCV, for 15 years. MDC will also pay
     Innogenetics a royalty of 10% of the Murex Group's net sales of
     Innogenetics' products. Also under this agreement, MDC shall fund
     agreed-upon research and development programs, beginning in 1998
     and for each of the following 13 years in an amount equal to 20%
     of the Murex Group's net sales of Innogenetics' products, subject
     to a cap.

16.  LITIGATION RESOLUTIONS:

     Four class action lawsuits were instituted on behalf of all
     persons who had purchased IMTC's securities between May 21, 1992
     and August 19, 1992 against IMTC, two executive officers of IMTC,
     and two shareholders. Although the defendants denied the
     allegations in the complaints, the parties agreed to settle all
     outstanding claims for $5,400 during 1996. In accordance with the
     Stipulation Settlement Agreement, the shareholders transferred
     185,886 common shares of the Company's stock to the Company to be
     used as their portion of the settlement. During 1997, the claims
     administrator finished qualifying claimants and submitted a
     motion to the U.S. District court setting out the final
     distribution for the settlement fund, which was approved by the
     Court during October 1997. The sum of damages claimed and
     expenses incurred by the claims administrator and Plaintiffs'
     counsel was less than the total settlement fund, consequently,
     the Company was entitled to the remaining cash of approximately
     $2,133 and 105,766 common shares of the Company's stock. These
     shares are valued at $615 ($5.81 per share), as defined by the
     settlement agreement. The reversion of the settlement fund has
     been reflected in the accompanying financial statements as an
     offset to general and administrative costs for the cash portion
     and an increase to additional paid-in-capital for the stock
     portion.

     During 1995, the U.K. Inland Revenue questioned the tax basis of
     inventory, accounts receivable and property, plant and equipment
     related to the 1992 purchase of assets from Wellcome. This matter
     was resolved during 1997, resulting in no additional tax payments
     or liabilities. The U.K. Inland Revenue have finalized their
     review of all tax returns through 1995, and all outstanding
     issues have been resolved.

     Several Subsidiaries of the Murex Group were involved in patent
     infringement litigation in several countries against Chiron and
     Ortho Diagnostic Systems, Inc. ("Ortho") related to Chiron's HCV
     patent. On August 28, 1996, IMTC reached a worldwide agreement
     with Chiron and Ortho concerning tests for HCV under which all
     litigation among the parties permanently ceased. As a result of
     the settlement with Chiron and Ortho, a reversal was made to
     royalty accruals made in prior years, which resulted in a net
     credit to royalty expense of $2,799 for the year ended December
     31, 1996.

17.  RESTRUCTURING:

     During September 1996, the Company recorded a restructuring
     charge of $2,100 before tax. The restructuring was driven by the
     need to reposition the Company for its movement into the patient
     monitoring business. The worldwide plan resulted in personnel
     reductions of approximately 50 people from various functions
     during 1997 and 1996. The restructuring provision consists
     predominantly of estimated costs for employee severance and other
     benefits. As of December 31, 1996, 35 employees left the Company
     related to the restructuring plan, resulting in actual payments
     of $698. As such, the remaining accrual at December 31, 1996 was
     $1,402. All remaining costs were incurred during 1997.

18.  SHAREHOLDER RIGHTS PLAN:

     In August 1995, IMTC adopted a Shareholder Rights Plan
     authorizing the distribution of one Right for each common share
     outstanding. The Rights are attached to the common shares and are
     not initially exercisable. Rights become exercisable in the
     circumstances described in the Shareholder Rights Plan, including
     ten days following the announcement that a person or group
     without prior approval from the Board of Directors has acquired,
     or obtained the right to acquire, beneficial ownership of 20
     percent or more of the outstanding common shares of IMTC or ten
     days following the announcement of a takeover bid, tender offer
     or exchange offer. In certain circumstances, the Rights may be
     redeemed by IMTC at a price of $.001 per Right. If not redeemed,
     the Rights expire in ten years.


19.  DOMESTIC AND FOREIGN OPERATIONS:

     Information concerning the Company's domestic and foreign
     operations for the years ended December 31, 1997, 1996 and 1995
     is summarized below. Murex Group product sales to affiliates are
     priced at market prices less an allowance for marketing,
     advertising and other sales costs.
<TABLE>
<CAPTION>

- -----------------------------------------------------------------------------------------------------------
                                              United                  Far East
                                  Canada      States      Europe     and Other   Eliminations  Consolidated
- -----------------------------------------------------------------------------------------------------------
December 31, 1997
- -----------------
Net Revenues:
<S>                            <C>          <C>         <C>          <C>          <C>             <C>     
      Unaffiliated Customers   $   2,111    $  26,755   $  56,897    $  20,369                 $ 106,132
      Affiliates                                  447      28,728       47,332    $ (76,507)
                               ---------    ---------   ---------    ---------    ---------    ---------
      Total                        2,111       27,202      85,625       67,701      (76,507)     106,132
Net Income (Loss)                 (2,966)       5,169      (7,130)      13,991                     9,064
Identifiable Assets                3,456       12,935      46,693       32,159                    95,243


December 31, 1996
- -----------------
Net Revenues:
      Unaffiliated Customers   $   1,995    $  24,228   $  59,461    $  15,167                 $ 100,851
      Affiliates                                  363      28,529        6,704    $ (35,596)
                               ---------    ---------   ---------    ---------    ---------    ---------
      Total                        1,995       24,591      87,990       21,871      (35,596)     100,851
Net Income (Loss)                 (4,789)       1,568      (2,860)       7,930                     1,849
Identifiable Assets                2,955       10,787      53,818       27,553                    95,113


December 31, 1995
- -----------------
Net Revenues:
      Unaffiliated Customers                $  21,698   $  61,165    $   9,531                 $  92,394
      Affiliates                                1,578      33,076        3,430    $ (38,084)
                                            ---------   ---------    ---------    ---------    ---------
      Total                                    23,276      94,241       12,961      (38,084)      92,394
Net Income (Loss)              $  (4,088)         966      (6,761)       3,273                    (6,610)
Identifiable Assets                4,808       10,305      55,925       14,710                    85,748


</TABLE>

<PAGE>


     EXPORT SALES BY DESTINATION

     Export sales of $112, $339, and $834 for the years ended December
     31, 1997, 1996 and 1995, respectively, originated in the United
     States. Export sales of $12,320, $9,838, and $8,794 for the years
     ended December 31, 1997, 1996 and 1995, respectively, originated
     in the United Kingdom. Additional export sales of $4,751, $6,967
     and $12,694, for the years ended December 31, 1997, 1996 and
     1995, respectively, originated in other European countries and
     $1,193 and $5,181 originated in Barbados for the years ended
     December 31, 1997 and 1996, respectively. Also in 1997, export
     sales from South Africa to other African countries were $911. The
     table below summarizes export sales by destination.

                                           Middle East
                    Europe        Asia      and Africa      Other       Total
- --------------------------------------------------------------------------------
December 31:
1997               $ 6,824      $ 5,118      $ 7,145      $   200      $19,287
1996                 7,388        5,349        9,588                    22,325
1995                13,447        2,160        6,154          561       22,322
- --------------------------------------------------------------------------------


20.  SUBSEQUENT EVENTS:

     On January 14, 1998 the Company amended its existing interest
     rate swap agreement to increase the notional principal amount to
     $10,000 and extend the contract to January 14, 2003. This
     agreement fixed the LIBOR portion of the interest rate at 6.48%.
     The Company specifically designated this interest rate swap
     agreement as a hedge of the line of credit, and therefore will
     recognize the differential paid or received as an adjustment to
     interest expense in the period in which it occurs.

21.  RECONCILIATION OF CANADIAN AND U.S. GENERALLY ACCEPTED ACCOUNTING
     PRINCIPLES ("CANADIAN GAAP" AND "U.S. GAAP") :

     There were no differences between Canadian GAAP and U.S. GAAP
     during the years ended December 31, 1997, 1996 and 1995.



<PAGE>



International Murex Technologies Corporation
- --------------------------------------------
INDEPENDENT AUDITORS' REPORT


To the Board of Directors and Shareholders of
International Murex Technologies Corporation:

     We have audited the accompanying consolidated balance sheets of
International Murex Technologies Corporation and subsidiaries as of
December 31, 1997 and 1996 and the related consolidated statements of
operations, changes in shareholders' equity, and cash flows for each
of the three years in the period ended December 31, 1997. These
financial statements are the responsibility of the Company's
management. Our responsibility is to express an opinion on these
financial statements based on our audits.

     We conducted our audits in accordance with generally accepted
auditing standards. Those standards require that we plan and perform
the audit to obtain reasonable assurance about whether the financial
statements are free of material misstatement. An audit includes
examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements. An audit also includes
assessing the accounting principles used and significant estimates
made by management, as well as evaluating the overall financial
statement presentation. We believe that our audits provide a
reasonable basis for our opinion.

     In our opinion, such consolidated financial statements present
fairly, in all material respects, the financial position of
International Murex Technologies Corporation and its subsidiaries at
December 31, 1997 and 1996 and the results of their operations and
their cash flows for each of the three years in the period ended
December 31, 1997 in conformity with generally accepted accounting
principles.



DELOITTE & TOUCHE LLP
Atlanta, Georgia
February 13, 1998




<PAGE>



ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON ACCOUNTING
        AND FINANCIAL DISCLOSURE

        None.


                               PART III

ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

     The required information is hereby incorporated by reference to
the sections entitled "Election of Directors" and "Shares Held by
Nominees for Election of Directors" in IMTC's Proxy Statement for the
1998 Annual Meeting of Shareholders to be held June 4, 1998. IMTC will
file with the Securities and Exchange Commission pursuant to
Regulation 14A a definitive Proxy Statement involving the election of
directors not later than 120 days after December 31, 1997.

ITEM 11. EXECUTIVE COMPENSATION

     The required information is hereby incorporated by reference to
the section entitled "Compensation of Executive Officers" in IMTC's
Proxy Statement for the 1998 Annual Meeting of Shareholders.

ITEM 12. SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND
         MANAGEMENT

     The required information is hereby incorporated by reference to
the sections entitled "Voting Shares," "Shares Held by Nominees for
Election of Directors," and "Beneficial Owners of More Than 5% of
Voting Stock" in IMTC's Proxy Statement for the 1998 Annual Meeting of
Shareholders.

ITEM 13. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     The required information is hereby incorporated by reference to
the section entitled "Interest of Certain Persons in Matters to be
Acted Upon" in IMTC's Proxy Statement for the 1998 Annual Meeting of
Shareholders.







<PAGE>



                                PART IV

ITEM 14. EXHIBITS, FINANCIAL STATEMENTS, AND REPORTS ON FORM 8-K

     (a)  Documents Filed as Part of This Report:

          (1)  Financial Statements

               Included in Part II, Item 8 of this Report:

               Consolidated Balance Sheets as of December 31, 1997 and
               1996.

               Consolidated Statements of Operations for each of the
               three years in the period ended December 31, 1997.

               Consolidated Statements of Changes in Shareholders'
               Equity for each of the three years in the period ended
               December 31, 1997.

               Consolidated Statements of Cash Flows for each of the
               three years in the period ended December 31, 1997.

               Notes to Consolidated Financial Statements.

               Independent Auditors' Report

          (2)  Financial Statement Schedule:

               Included in Part IV of this Report:
                                                                Schedule   Page
                                                                --------   ----
               Independent Auditors' Consent and Report
                    on Schedule                                    --       44

               Valuation and Qualifying Accounts                   II       45

               All financial statement schedules other than those
               listed above have been omitted as exhibits because they
               are not applicable or required under Regulation S-X.

               Items 10 through 13 of this Report incorporate only the
               indicated portions of IMTC's Proxy Statement for the
               1998 Annual Meeting of Shareholders. No other portion
               of such Proxy Statement shall be deemed to be
               incorporated herein or filed with the Securities and
               Exchange Commission.

        (b)    Reports on Form 8-K

               None

        (c)    Exhibits.

               The following exhibits are filed with or incorporated
               by reference in this Report. If such filing is made by
               incorporation by reference to a previously filed
               report, such report is identified in parentheses. See
               the Index of Exhibits included with the exhibits filed
               as part of this Report.



<PAGE>



Exhibit
Number         Document
- ------         --------

3.1            Memorandum of Association of IMTC dated October 31,
               1983, as amended on June 16, 1986, December 5, 1988,
               February 20, 1989, December 11, 1990 and December 11,
               1990 (Exhibit 3.1 to Registration Statement on Form
               S-1, No. 33-35422 ("Registration Statement") and
               Exhibit 3.3 to Post-Effective Amendment No. 3 to
               Registration Statement)

3.2            Articles of Association of IMTC dated October 31, 1983,
               as amended November 29, 1985 (Exhibit 3.2 to
               Registration Statement)

3.3            Amendments to Memorandum of Association (Exhibit 3.3 to
               the Company's Post-Effective Amendment No. 3 to
               Registration Statements and Schedule A to the Company's
               Proxy Statement dated June 7, 1994)

3.4            Amendments to Articles of Association of IMTC passed by
               Special Resolution on June 7, 1994 as filed on May 2,
               1995 (Exhibit 3.4 to the Company's Annual Report on
               Form 10-K for the fiscal year ended December 31, 1995)

4.1            IMTC Stock Option Plan (Exhibit 4.2 to the Company's
               Annual Report on Form 10-K for the fiscal year ended
               December 31, 1991)

4.2            IMTC Employee Equity Incentive Plan, as amended
               (Schedule A to the Company's Proxy Statement dated June
               7, 1994)

4.3            IMTC Employee Stock Purchase Plan, (Schedule B to the
               Company's Proxy Statement dated May 14, 1993)

4.3.1          IMTC Amended and Restated Employee Stock Purchase Plan
               (Schedule A to the Company's Proxy Statement dated
               April 3, 1997)

4.4            Warrant Indenture dated July 15, 1993 between IMTC and
               Montreal Trust of Canada. (Exhibit 4 to the Company's
               Current Report on Form 8-K dated July 27, 1993)

4.5            Shareholder Protection Rights Agreement between IMTC
               and The Bank of New York, as Rights Agent, dated August
               31, 1996 (Exhibit 4.1 to the Company's Current Report
               on Form 8-K dated August 31, 1995)

10.1           Pooling Agreement dated December 16, 1985 among IMTC,
               Central Guaranty Trust Company and Axon Limited, Murex
               Medical Research Limited, Semiotic Research Limited
               Partnership and Coral Sociedade Brasileira de Pesquisas
               e Desenvolvimento (Exhibit 10.9 to Registration
               Statement)

10.2           Escrow Agreement among Edward J. DeBartolo, Jr.,
               Central Guaranty Trust Company and Murex Clinical
               Technologies Corporation (Exhibit 10.33 to Current
               Report on Form 8-K dated October 26, 1990)

10.3           Employment Agreement dated as of January 1, 1992
               between IMTC and F. Michael P. Warren (Exhibit 10.10 to
               the Company's Annual Report on Form 10-K for the fiscal
               year ended December 31, 1995 (the "1995 Form 10-K"))

10.3.1         Employment Agreement dated as of January 1, 1992
               between MDC (formerly International Murex Technologies
               Limited which was formerly Sishui Funds Limited) and F.
               Michael P. Warren (Exhibit 10.10.1 to the 1995 Form
               10-K)

10.3.2         Employment Agreement dated as of January 1, 1992
               between MDL and F. Michael P. Warren (as assigned to
               MBL effective January 31, 1996) (Exhibit 10.10.2 to the
               1995 Form 10-K)

10.3.3*        Employment Agreement dated August 1, 1997 between IMTC
               and F. Michael P. Warren



<PAGE>

10.3.4*        Employment Agreement dated August 1, 1997 between Murex
               Biotech Limited and F. Michael P. Warren

10.3.5*        Employment Agreement dated August 1, 1997 between Murex
               Diagnostics Corporation and F. Michael P. Warren

10.4           Employment Agreement dated as of January 1, 1995
               between IMTC and C. Robert Cusick (Exhibit 10.11.1 to
               the 1995 Form 10-K)

10.4.1.*       Employment Agreement dated August 1, 1997 between IMTC
               and C. Robert Cusick

10.4.2*        Amendment to Employment Agreement dated November 6,
               1997 between IMTC and C. Robert Cusick

10.5           Employment Agreement dated as of January 1, 1995
               between IMTC and J. David Tholen (Exhibit 10.13.1 to
               the 1995 Form 10-K)

10.5.1         Separation Agreement dated as of January 20, 1997
               between IMTC and J. David Tholen (Exhibit 10.13.1 to
               the 1995 Form 10-K)

10.6           Redemption Agreement dated December 30, 1994 among
               NuBio Technologies Corporation, IMTC, IMTC Holdings,
               Inc. Dominion Biologicals Limited, Blaine MacNeil,
               Patrick Waddy and Samuel A. Brushett (Exhibit 10.18.1
               to the 1995 Form 10-K)

10.7           License Agreement dated May 3, 1994 between IMTC and
               Abbott Laboratories (Exhibit 10.1 to the Company's
               Quarterly Report on Form 10-Q dated May 13, 1994)

10.8           Stock Purchase Agreement dated May 31, 1994 between
               Digene Diagnostics, Inc. ("Digene") and International
               Murex Technologies Limited ("IMTL") for the purchase of
               1994 Series Preferred Stock (Exhibit 10.20 to the 1995
               Form 10- K)

10.8.1         Escrow Agreement dated May 31, 1994 among IMTL, Digene
               and Reid & Priest LLP (Exhibit 10.20.1 to the 1995 Form
               10-K)

10.8.2         Shareholders Agreement dated May 31, 1994 among IMTL,
               Armonk Partners and Digene (Exhibit 10.20.2 to the 1995
               Form 10-K )

10.9           Employment Agreement dated as of July 1, 1995 between
               IMTC and Steven C. Ramsey (Exhibit 10.19 to the 1995
               Form 10-K)

10.9.1*        Amendment to Employment Agreement dated November 6,
               1997 between IMTC and Steven C. Ramsey

10.10          Distribution, Development and License Agreement between
               MDC and Innogenetics dated January 31, 1996 (Exhibit
               10.20 to the 1995 Form 10-K)

10.11          Agreement among Chiron Corporation, Johnson &
               Johnson/Ortho Diagnostics Systems, Inc. and
               International Murex Technologies Corporation dated
               August 27, 1996, without exhibits (Exhibit 10 to the
               Company's Quarterly Report on Form 10-Q for the period
               ended September 30, 1996)

10.12          Letter Agreement dated January 12, 1996 between Guido
               Guidetti and MDL (as assigned to MBL effective January
               31, 1996) (Exhibit 10.12 to the Company's Annual Report
               on Form 10-K for the year ended December 31, 1996 (the
               "1996 Form 10-K"))

10.13          Letter Agreement dated January 12, 1996 between P.
               Silveston and MDL (as assigned to MBL effective January
               31, 1996) (Exhibit 10.13 to the 1996 Form 10-K).

10.14          Credit Agreement (without schedules or exhibits) dated
               as of November 12, 1996 among IMTC, Murex Diagnostics
               International, Inc. ("MDII"), IMTC Holdings, Inc.
               ("Holdings U.S."), MDC, IMTC Holdings (U.K.) Limited
               ("Holdings U.K."), MDI and MBL, as the borrowers; Bank


<PAGE>


               of America Illinois and Bank of America National Trust
               and Savings Association, as issuing banks ("BOA"); Bank
               of America, F.S.B., as agent and lender ("BAFSB"), et
               al.,as the lenders, in the original principal amount of
               $15,000,000 (Exhibit 10.14 to the 1996 Form 10-K).

10.14.1*       First Amendment to Credit Agreement dated December 31,
               1997 among IMTC, MDII, MDC, Holdings U.K., MDI and MBL,
               as the borrowers, and BOA and BAFSB, et.al., as the
               lenders. 10.15 Promissory Note dated November 12, 1996
               executed by IMTC, MDII, Holdings U.S., MDC, Holdings
               U.K., MDI and MBL to the order of BAFSB in the original
               principal amount of $8,000,000 (Exhibit 10.15 to the
               1996 Form 10-K).

10.16          Offshore Currency Promissory Note dated November 12,
               1996 executed by Holdings U.K. and MBL to the order of
               BOA (Exhibit 10.16 to the 1996 Form 10-K).

10.17          Security Agreement (without schedules) executed by
               Holdings U.S., MDI and IMTC in favor of BASFB (Exhibit
               10.17 to the 1996 Form 10-K).

10.18          Deed of Charge executed by Holdings U.K. in favor of
               BOA (Exhibit 10.18 to the 1996 Form 10-K).

10.19          Deed of Charge executed by MBL in favor of BOA (Exhibit
               10.19 to the 1996 Form 10-K).

10.20          Debenture executed by MDII and MDC in favor of BASFB
               (Exhibit 10.20 to the 1996 Form 10-K).

21*            Subsidiaries

24*            Powers of Attorney


*  Filed with this Report


(b)            Exhibits required by Item 601 of Regulation S-K.

               See Item 14(a)(3) above.

(c)            Financial Statement Schedule.

               See Item 14(a)(2) above.




<PAGE>



                              SIGNATURES

     Pursuant to the requirements of Section 13 or 15(d) of the
Securities Exchange Act of 1934, the Registrant has duly caused this
report to be signed on its behalf by the undersigned, thereunto duly
authorized:

                                           INTERNATIONAL MUREX TECHNOLOGIES
                                           CORPORATION



                                           By:   /s/ C. Robert Cusick
                                                --------------------------------
                                                C. Robert Cusick, Vice Chairman,
                                                Chief Executive Officer,
                                                President and Director

DATE: March 6, 1998
      -------------

     Pursuant to the requirements of the Securities Exchange Act of
1934, this report has been signed below by the following persons on
behalf of the Registrant and in the capacities indicated on March 6,
1998.


          Signature                                   Title
          ---------                                   -----

     /s/ C. Robert Cusick                Vice Chairman, CEO/President and
- -------------------------------------      Director
         C. Robert Cusick
       * F. Michael P. Warren, Q.C.        Chairman of the Board of Directors
- -------------------------------------
       F. Michael P. Warren, Q.C.
       * J. Trevor Eyton, O. C.            Director
- -------------------------------------
      J. Trevor Eyton, O. C.
        * Thomas L. Gavan, M.D.            Director
- -------------------------------------
       Thomas L. Gavan, M.D.
        * Norbert Gilmore, M.D.            Director
- -------------------------------------
       Norbert Gilmore, M.D.
       * Jay A. Lefton, Esq.               Director
- -------------------------------------
        Jay A. Lefton, Esq.
 *Hartland M. MacDougall, O.C.             Director
- -------------------------------------
  Hartland M. MacDougall, O.C.
        * Stanley E. Read, M.D.            Director
- -------------------------------------
       Stanley E. Read, M.D.
          *Victor A. Rice                  Director
- -------------------------------------
          Victor A. Rice


                                           Vice President, Chief
*By: /s/ Steven C. Ramsey                  Financial Officer and
- -------------------------------------
       Steven C. Ramsey, as                Authorized  Representative in
         Attorney-in-Fact                  the United States



             INTERNATIONAL MUREX TECHNOLOGIES CORPORATION



<PAGE>



          INDEX TO CONSOLIDATED FINANCIAL STATEMENT SCHEDULES


                                                                            Page
                                                                            ----

   --      Independent Auditors' Consent and Report on Schedules.............45
  II.      Valuation and Qualifying Accounts.................................46





<PAGE>



INDEPENDENT AUDITORS' CONSENT AND REPORT ON SCHEDULE



Board of Directors and Shareholders
International Murex Technologies Corporation:

We consent to the incorporation by reference in Registration
Statements No. 33-40726 and No. 333-44629 of International Murex
Technologies Corporation on Form S-8 of our report dated February 13,
1998 appearing in the Annual Report on Form 10-K of International
Murex Technologies Corporation for the year ended December 31, 1997.

Our audits of the consolidated financial statements referred to in our
aforementioned report also included the financial statement schedule
of International Murex Technologies Corporation, listed in Item 14.
This financial statement schedule is the responsibility of the
Company's management. Our responsibility is to express an opinion
based on our audits. In our opinion, such financial statement
schedule, when considered in relation to the basic consolidated
financial statements taken as a whole, presents fairly in all material
respects the information set forth therein.


DELOITTE & TOUCHE LLP

Atlanta, Georgia
March 10, 1998








<PAGE>



INTERNATIONAL MUREX TECHNOLOGIES CORPORATION
Schedule II - Valuation and Qualifying Accounts
For the years ended December 31, 1997, 1996, and 1995
(Expressed in U.S. Dollars)
- --------------------------------------------------------------------------------

<TABLE>
<CAPTION>
                                               ADDITIONS                         DEDUCTIONS
                                    -------------------------------    ------------------------------
                                 BALANCE AT     CHARGED TO                                                 BALANCE AT
                                  BEGINNING     COSTS AND    TRANSLATION    TRANSLATION                      END OF
     DESCRIPTION                  OF PERIOD     EXPENSES      ADJUSTMENT    ADJUSTMENT     WRITE-OFF        PERIOD
     -----------                  ---------     --------      ----------    ----------     ---------        ------
<S>                               <C>             <C>          <C>            <C>           <C>              <C>

Year ended December 31, 1997:
     Allowance for
      Doubtful Accounts         $ 3,174,000   $   171,000                  $  (249,000)   $  (157,000)   $ 2,939,000
     Inventory Reserve            5,490,000       439,000                     (157,000)    (1,012,000)     4,759,000
Year ended December 31, 1996:
     Allowance for
      Doubtful Accounts           3,410,000       257,000   $   282,000                      (775,000)     3,174,000
     Inventory Reserve            3,954,000     3,669,000       297,000                    (2,430,000)     5,490,000
Year ended
  December 31, 1995:
  Allowances for
    Doubtful Accounts             2,097,000     1,682,000       124,000                      (493,000)     3,410,000
   Inventory Reserve              2,581,000     1,424,000       124,000                      (175,000)     3,954,000


</TABLE>





<PAGE>


                           INDEX OF EXHIBITS

        The exhibits listed below are filed with this Report.


  Exhibit
  Number                           Document
  ------                           --------

10.3.3*      Employment Agreement dated August 1, 1997 between IMTC
             and F. Michael P. Warren

10.3.4*      Employment Agreement dated August 1, 1997 between Murex
             Biotech Limited and F. Michael P. Warren

10.3.5*      Employment Agreement dated August 1, 1997 between Murex
             Diagnostics Corporation and F. Michael P. Warren

10.4.1.*     Employment Agreement dated August 1, 1997 between IMTC
             and C. Robert Cusick

10.4.2*      Amendment to Employment Agreement dated November 6, 1997
             between IMTC and C. Robert Cusick

10.9.1*      Amendment to Employment Agreement dated November 6, 1997
             between IMTC and Steven C. Ramsey

10.14.1*     First Amendment to Credit Agreement dated December 31,
             1997 among IMTC, MDII, MDC, Holdings U.K., MDI and MBL as
             the borrowers; and BOA and BAFSB, et.al., as the lenders.

21           Subsidiaries

24           Powers of Attorney








          THIS AGREEMENT is made      1st day of   August, 1997 ("the
          Effective Date") by and between INTERNATIONAL MUREX TECHNOLOGIES
          CORPORATION, incorporated under the laws of the Province of
          British Columbia (the "Company"), and F MICHAEL P WARREN
          ("Executive").

          WHEREAS, the Company and Executive previously entered into an
          Employment Agreement dated January 1, 1992; and

          WHEREAS, the term of the employment relationship created by such
          Employment Agreement has not expired; and

          WHEREAS, the Company and Executive desire to amend and restate
          the terms and conditions of their employment relationship as it
          relates to the period subsequent to 1 August, 1997.

          NOW THEREFORE, in consideration of the foregoing and the mutual
          agreements contained herein, the Company and the Executive agree
          as follows:

          1.     Employment
                 ----------

                 The Company hereby employs Executive, and Executive
                 accepts such employment and agrees to perform services for
                 the Company, for the period and upon the other terms and
                 conditions set forth in this Agreement.

          2.     Term
                 ----

                 The initial term of Executive's employment hereunder shall
                 be for a period of three (3) years, commencing as of 1
                 August 1997 (the "Commencement Date") subject to earlier
                 termination as hereinafter specified in Section 8.  At
                 each anniversary date of the Commencement Date (each a
                 "Renewal Date"), the then remaining term of this Agreement
                 shall be extended for an additional one year period in
                 addition to the then remaining term unless either party
                 hereto shall have provided written notice to the other
                 party of such non-renewal of this Agreement on or within
                 three (3) months before such Renewal Date.  In the event
                 that either party shall provide the other party with
                 written notice of non-renewal of this Agreement, this
                 Agreement shall not be extended as of any subsequent
                 Renewal Date but shall remain effective in accordance with
                 its terms (subject to termination in accordance with
                 Section 8 hereof) until the end of the then current term
                 of this Agreement.  A non-renewal of this Agreement in
                 accordance with this Section 2 shall not constitute a
                 termination of this Agreement for the purpose of Sections
                 5 or 8.

          3.     Position and Duties  
                 -------------------

          3.1    Service with the Company. During the Term of this
                 Agreement, Executive shall serve in such position as
                 Executive and the Board of Directors shall from time to
                 time agree.  In such position, Executive agrees to perform
                 such executive employment duties consistent with such
                 position as the Board of Directors of the Company shall
                 assign to him from time to time.  Executive also agrees to
                 serve, during the Term hereof, as requested by the Board,
                 and without any additional compensation, as a Director of
                 the Company and as an executive officer and/or director of
                 any corporations affiliated with the Company.  The
                 compensation payable to Executive herein shall be paid by
                 the Company or by a subsidiary of the Company as
                 designated by Executive.

          3.2    Performance of Duties. Executive agrees to serve the
                 Company faithfully and to the best of his ability and to
                 devote the time, attention and efforts necessary to
                 advance the business and affairs of the Company during the
                 Term of this Agreement.  It is understood and agreed that
                 Executive may pursue personal investments requiring time
                 commitments that do not conflict with his obligations to
                 the Company, including those in the preceding sentence. 
                 Executive hereby confirms that he is under no contractual
                 commitments inconsistent with his obligations set forth in
                 this Agreement, and that during the Term of this
                 Agreement, he shall not render or perform services, or
                 enter into any contract to do so, for any other
                 corporation, firm, entity or person which are inconsistent
                 with the provisions of this Agreement.

          4.     Compensation
                 ------------

          4.1    Base Salary
                 -----------

                 As compensation for all services to be rendered by
                 Executive under this Agreement, the Company shall pay to
                 Executive an initial base annual salary (the "Base
                 Salary") of US$11,912 which salary shall be paid in semi-
                 monthly instalments in accordance with the Company's
                 normal payroll procedures and policies.  The base salary
                 shall be increased on January 1, 1998 and on each January
                 1 thereafter by the percentage equal to the percentage
                 increase in the Consumer Price Index maintained by the
                 United States Bureau of Labor Statistics for the Atlanta,
                 Georgia metropolitan area or an equivalent index (the
                 "Index") as of January 1 of such year over the Index for
                 the immediately preceding January 1.  Should the Index be
                 modified or discontinued, appropriate adjustment shall be
                 made to reflect such modification or to refer to a similar
                 index.   Additionally, Executive's Base Salary shall be
                 reviewed annually and may be increased by an amount to be
                 determined by the Compensation/Option Committee (the
                 "Committee") on the basis of Executive's performance.

          4.2    Incentive Compensation
                 ----------------------

                 In addition to the Base Salary described in Section 4.1,
                 Executive shall be eligible to receive incentive
                 compensation pursuant to the Senior Management Incentive
                 Plan as approved by the Committee or such other plans as
                 may from time to time be available.

          4.3    Deferral of Compensation
                 ------------------------

                 Executive shall be entitled to elect to defer the receipt
                 of up to seventy-five percent (75%) of his Base Salary and
                 Incentive Compensation for each calendar year during which
                 this Agreement is in effect.  Executive shall make the
                 election to defer his compensation for a calendar year by
                 giving written notice to the Company of his desire to do
                 so in writing no later than December 31 of the immediately
                 preceding calendar year.  In the event that Executive
                 elects to defer the payment of any compensation due
                 hereunder in the manner contemplated by this Section 4.3,
                 the terms and conditions set forth in Exhibit A hereto
                 with respect to the circumstances under which Executive
                 shall be entitled to the payment of the deferred
                 compensation as well as the interest earned thereon and
                 the timing and method of those payments shall be
                 applicable. Also in such event, each of the periodic
                 payments of Executive's Base Salary for any year in which
                 Executive has elected to defer receipt of a portion of his
                 Base Salary shall be reduced by the percentage amount of
                 his total Base Salary which he has elected to defer.

          4.4    Participation in Benefit Plans
                 ------------------------------

                 Executive shall also be entitled to the extent that his
                 position, title, tenure, salary, age, health and other
                 qualifications make him eligible, to participate in all
                 employee benefit plans or programs (including
                 medical/dental and life insurance, retirement pension,
                 stock option incentives, vacation time, sick leave and
                 holidays) of the Company currently in existence on the
                 date hereof or as may hereafter be instituted from time to
                 time.  Executive's participation in any such plan or
                 program shall be subject to the provisions, rules and
                 regulations applicable thereto.

          4.5    Expenses
                 --------

                 In accordance with the Company's policies established from
                 time to time, the Company shall pay or reimburse Executive
                 for all reasonable and necessary out-of-pocket expenses
                 incurred by him in the performance of his duties under
                 this Agreement, subject to the timely presentment of
                 appropriate vouchers and receipts.

          4.6    Vacation
                 --------

                 Executive will be entitled to the highest number of
                 vacation days with full pay during each twelve months in
                 which this Agreement is in effect as are available to any
                 other key United States corporate executive of the
                 Company, without any reduction based upon length of
                 service to the Company.

          4.7    Double Tax Liability
                 --------------------

                 In the event that in any year during the term of this
                 Agreement Executive is required to pay income taxes on any
                 portion of his income for that year both to Canada and to
                 the United Kingdom, the Company shall pay to Executive the
                 amount which, after taking into account the taxes required
                 to be paid by Executive as a result of Executive's receipt
                 of such payment from the Company, shall cause Executive's
                 after-tax return on his income to equal the amount which
                 would have been available to Executive had no United
                 Kingdom taxes been due with respect to such income.  The
                 amounts due from the Company pursuant to the immediately
                 preceding sentence shall be determined by Executive's tax
                 return preparer, shall take into account any foreign tax
                 credits or other credits and deductions allowed against
                 his Canadian tax liability, and shall be paid to Executive
                 no later than fifteen days following the date on which
                 Executive files the first tax return in which the income
                 subject to taxation in both Canada and the United Kingdom
                 is reported in any year, or within fifteen days following
                 the date on which the relevant taxing authority determines
                 that Executive's income is subject to taxation both in
                 Canada and in the United Kingdom, as the case may be.

          4.8    Tax and Estate Planning
                 -----------------------

                 The Company agrees to reimburse Executive for the cost of
                 financial, tax and estate planning for each 365 day period
                 in which this Agreement is in effect in amount not to
                 exceed US$3,000 (net of any tax required to be paid by
                 Executive on such reimbursement) for each 365 day period. 
                 In the event that Executive is required to pay any tax on
                 such reimbursement, the amount to be reimbursed to
                 Executive shall be grossed up by such amount as shall
                 ensure that Executive receives the same amount as he would
                 have received had no such tax been payable.

          4.9    Additional Benefits
                 -------------------

                 During the term of this Agreement, Executive shall be
                 entitled to participate in all present and future employee
                 benefit plans and all other compensation and benefit
                 plans, programs and structures as may from time to time be
                 made available by the Company to all other key corporate
                 executives of the Company, and on terms and conditions no
                 less favourable than those generally available to other
                 such employees.  In the event that the Company elects to
                 obtain key man life insurance insuring Executive,
                 Executive shall make himself available for the necessary
                 physical examinations and shall co-operate in all other
                 respects with the Company's efforts to obtain such
                 insurance.

          5.     Compensation upon Termination
                 -----------------------------

                 (a)    In the event this Agreement is terminated pursuant
                        to sub-section 8.1(a) hereof, in addition to any
                        benefits to which Executive may then or following
                        the termination of his employment be entitled under
                        any other applicable policy or plan of the Company
                        then in effect (including basic life insurance
                        which coverage equals two times annual salary, and
                        survivor benefits which provide Accidental Death
                        and Dismemberment for each employee at two times
                        the annual salary), the Company shall pay to
                        Executive's estate his Base Salary, incentive
                        compensation and benefits due through the effective
                        date of termination.  In the event that such
                        termination occurs on any date other than the last
                        day of the fiscal year, the incentive compensation
                        shall be based upon the performance goals achieved
                        at the end of the fiscal year, but shall be
                        prorated based upon the number of days which have
                        elapsed in the fiscal year through the date of
                        termination.  Payment of this incentive
                        compensation or release of any stock representing
                        incentive compensation due under this Section 5(a)
                        shall be made no later than 120 days following the
                        end of the fiscal year with respect to which it is
                        being paid.  Payment of all other amounts under
                        this Section 5(a) shall be made not later than the
                        30th day following the effective date of
                        termination.  Executive's estate shall be entitled
                        to receive an amount equal to twenty-four (24)
                        times his then current monthly Base Salary.

                 (b)    In the event this Agreement is terminated pursuant
                        to Sub-section 8.1(b)(i) hereof, Executive or his
                        representative shall be entitled to receive an
                        amount equal to twenty-four (24) times his then
                        current monthly Base Salary, less any disability
                        insurance benefits payable to Executive during such
                        twenty-four month period from disability policies
                        provided by the Company.

                 (c)    In the event this Agreement is terminated pursuant
                        to Sub-section 8.1(b)(ii) or (iii) hereof,
                        Executive shall not be entitled to any compensation
                        other than his then current Base Salary which has
                        accrued through his date of termination, subject to
                        the Company's right of offset based upon acts of
                        Executive which gave rise to the termination.

                 (d)    In the event this Agreement is terminated pursuant
                        to Sub-section 8.1(c) hereof, Executive shall be
                        entitled to a severance allowance equal to the
                        greater of (i) his Base Salary for all months
                        remaining in his then current term, or (ii) his
                        then current monthly Base Salary for twenty-four
                        (24) months.

                 (e)    Subject to Section 5(a) payments or the release of
                        stock representing compensation to Executive
                        pursuant to this Section 5 shall be made in either
                        a lump sum payment or, at the sole discretion of
                        the Company in four (4) equal payments within six
                        (6) months of termination of this Agreement.

                 (f)    In the event that Executive is terminated pursuant
                        to Subsections 8.1(a), 8.1(b)(i) or 8.1(c) hereof,
                        the expiration dates of Executive's options
                        currently outstanding pursuant to any of the
                        Company's stock option plans will be extended
                        twenty-four (24) months from the date of such
                        termination.

          6.     Confidential Information
                 ------------------------

                 Except as permitted or directed by the Company's Board of
                 Directors, Executive shall not during the Term of this
                 Agreement or at any time thereafter divulge, furnish or
                 make accessible to anyone for use in any way (other than
                 in the ordinary course of the business of the Company) any
                 confidential or secret knowledge or information of the
                 Company (for the purposes of Sections 6 through 8 hereof,
                 the term "Company" shall be deemed to include any
                 subsidiary or affiliate of the Company) which Executive
                 has acquired or become acquainted with or will acquire or
                 become acquainted with prior to the termination of the
                 period of his employment by the Company, whether developed
                 by himself or by others, concerning any trade secrets,
                 confidential or secret designs, processes, formulae,
                 plans, devices or material (whether or not patented or
                 patentable) directly or indirectly useful in any aspect of
                 the business of the Company, and confidential customer or
                 supplier lists of the Company, any confidential or secret
                 development or research work of the Company, or any other
                 confidential or secret aspects of the business of the
                 Company.  Executive acknowledges that the above described
                 knowledge or information constitutes a unique and valuable
                 asset of the Company acquired at great time and expense by
                 the Company and its predecessors, and that any disclosure
                 or other use of such knowledge or information other than
                 for the sole benefit of the Company would be wrongful and
                 would cause irreparable harm to the Company.  Both during
                 and after the Term of this Agreement, Executive shall
                 refrain from any acts or omissions that would reduce the
                 value of the use of such knowledge or information to the
                 Company.  The foregoing obligations of confidentiality,
                 however, shall not apply to any knowledge or information
                 which is now published or which subsequently becomes
                 generally publicly known, other than as a direct or
                 indirect result of the breach of this Agreement by
                 Executive.

          7.     Non-Competition, Solicitation of Customers, Solicitation
                 --------------------------------------------------------
                 of Employees
                 ------------

          7.1    Non-Competition
                 ---------------

                 (a)    Executive agrees that, during the period of his
                        employment hereunder and for a period of one (1)
                        year following the termination of such employment,
                        he shall not directly engage in competition with
                        the Company within the "Territory" (as hereinafter
                        defined) in any management capacity in any phase of
                        the Company's business of developing,
                        manufacturing, distributing, marketing, leasing or
                        selling any of the products which the Company is in
                        the business of developing, manufacturing,
                        distributing, marketing, leasing to others or
                        selling (the "Competitive Areas") during the Term
                        of this Agreement or which the Company has
                        definitive plans to develop, manufacture or market.

                 (b)    The "Territory" shall be that area throughout the
                        world in which the Company presently markets its
                        products.  This Agreement shall be deemed
                        automatically amended without the need of further
                        action by any party to add to any new countries or
                        parts thereof where after the date hereof and prior
                        to the termination of Executive's employment the
                        Company begins to market it products and to delete
                        any countries after no Company products have been
                        sold there for a period of six months.

                 (c)    The restrictions in this Section 7 shall not apply
                        with respect to (i) a passive investment by
                        Executive of less than 5% of the outstanding shares
                        of capital stock of any corporation, or (ii)
                        employment by Executive with an entity in a
                        management capacity in an area of business which is
                        not, directly or indirectly, a Competitive Area.

          7.2    Agreement Not to Solicit Customers. Executive agrees that
                 during his employment by the Company hereunder and for the
                 two (2) year period following the termination of such
                 employment, he shall not, without the prior written
                 consent of the Company, within the Territory, either
                 directly or indirectly, on his own behalf or in the
                 service or on behalf of others, solicit, divert or
                 appropriate, or attempt to solicit, divert or appropriate,
                 to any competing business any person or entity whose
                 account with the Company was sold or serviced by or under
                 the supervision of Executive during the year preceding the
                 termination of such employment.

          7.3    Agreement Not to Solicit Employees. Executive agrees that
                 during his employment by the Company hereunder and for the
                 two (2) year period following the termination of such
                 employment, he shall not, either directly or indirectly,
                 on his own behalf or in the service or on behalf of
                 others, solicit, divert, or attempt to solicit or divert
                 any person then employed by the Company.

          8.     Termination
                 -----------

          8.1    Grounds of Termination
                 ----------------------

                 This Agreement shall terminate prior to the expiration of
                 the Initial Term set forth in Section 2 or any extension
                 thereof in the event that at any time during such Initial
                 Term or any extension thereof:

                 (a)    Executive shall die; or

                 (b)    The Board of Directors of the Company shall
                        determine that:

                        (i)    Executive has become disabled; or

                        (ii)   Executive has breached this Agreement in any
                               material respect, which breach is not cured
                               by Executive or is not capable of being
                               cured (as determined in the sole discretion
                               of the Company's Board of Directors) by
                               Executive within thirty (30) days after
                               written notice of such breach is delivered
                               to Executive; or

                        (iii)  in its sole discretion Cause exists. 
                               "Cause" means (A) conduct amounting to
                               fraud, embezzlement or misappropriation as
                               against the Company, (B) the wilful and
                               knowing material breach of any fiduciary
                               duty owed to the Company as an officer of
                               the Company other than done at the direction
                               of the Board of Directors, (C) having been
                               convicted of a criminal offence which may
                               have a material adverse effect on the
                               Company or the ability of Executive to carry
                               out his duties of employment, or (D) the
                               knowing failure of Executive to follow
                               specific directives of the Board of
                               Directors of the Company consistent with his
                               duties.  If the Board of Directors
                               terminates this Agreement pursuant to this
                               Section 8.01(b)(iii), Executive will be
                               provided ninety (90) days written notice.

                 (c)    The Board of Directors of the Company shall
                        determine, in its sole discretion, that the
                        termination of this Agreement is in the best
                        interest of the Company, and in which event
                        Executive shall have no duty to mitigate his
                        damages. If the Board of Directors terminates this
                        Agreement pursuant to this Section 8.1(c) Executive
                        will be provided ninety (90) days written notice.

                 Notwithstanding any termination of this Agreement,
                 Executive, in consideration of his employment hereunder to
                 the date of such termination, shall remain bound by the
                 provisions of this Agreement which specifically relate to
                 periods, activities or obligations upon or subsequent to
                 the termination of Executive's employment.

          8.2    "Disability" Defined
                 --------------------

                 The Board of Directors may determine that Executive has
                 become disabled, for the purpose of this Agreement, in the
                 event that Executive shall fail, because of illness or
                 other physical or mental incapacity, to render services of
                 the character contemplated by this Agreement for an
                 aggregate of more than twelve (12) weeks during any twelve
                 (12) month period.

          8.3    Surrender of Records and Property
                 ---------------------------------

                 Upon termination of his employment with the Company,
                 Executive shall deliver promptly to the Company all
                 records, manuals, books, blank forms, documents, letters,
                 memoranda, notes, notebooks, reports, data tables,
                 calculations or copies thereof, which are the property of
                 the Company and which relate in any way to the business,
                 products, practices or techniques of the Company, and all
                 other property, trade secrets and confidential information
                 of the Company, including, but not limited to, all
                 documents which in whole or in part contain any trade
                 secrets or confidential information of the Company, which
                 in any of these cases are in his possession or under this
                 control.

          9.     Assignment and Enurement
                 ------------------------

                 This Agreement shall enure to the benefit of and be
                 binding upon the parties hereto and their respective
                 heirs, successors, administrators, and permitted assigns. 
                 The Company may, without the consent of Executive, assign
                 its rights and obligations under this Agreement to any
                 corporation, firm or other business entity with or into
                 which the Company may merge or consolidate, or to which
                 the Company may sell or transfer all or substantially all
                 of its assets or of which 50% or more of the equity
                 investment and of the voting control is owned, directly or
                 indirectly, by, or is under common ownership with, the
                 Company; provided, however, that if the assignee was not
                 previously part of a consolidated group with the Company,
                 Executive will receive payments and benefits as outlined
                 in Exhibit B attached hereto and incorporated herein.

          10.    Injunctive Relief
                 -----------------

                 Executive agrees that it would be difficult to compensate
                 the Company fully for damages for any violation of the
                 provisions of this Agreement, including without limitation
                 the provisions of Sections 6, 7 and 8.3.  Accordingly,
                 Executive specifically agrees that the Company shall be
                 entitled to temporary and permanent injunctive relief to
                 enforce the provisions of this Agreement.  This provision
                 with respect to injunctive relief shall not however,
                 diminish the right of the Company to claim and recover
                 damages in addition to injunctive relief.
                 

          11.    Miscellaneous
                 -------------

          11.1   Governing Law
                 -------------

                 This Agreement is made under and shall be governed by and
                 construed in accordance with the laws of the Province of
                 Ontario subject to any principles of conflict of laws.

          11.2   Prior Agreements
                 ----------------

                 This Agreement contains the entire agreement of the
                 parties relating to the subject matter hereof and
                 supersedes all prior agreements and understandings with
                 respect to such subject matter, and the parties hereto
                 have made no agreements, representations or warranties
                 relating to the subject matter of this Agreement which are
                 not set forth herein.

          11.3   Withholding Taxes
                 -----------------

                 The Company may withhold from any benefits payable under
                 this Agreement all federal, state, city and other taxes as
                 shall be required pursuant to any law or governmental
                 regulation or ruling.

          11.4   Amendments
                 ----------

                 No amendment or modification of this Agreement shall be
                 deemed effective unless made in writing signed by the
                 party against whom enforcement of the waiver or estoppel
                 is sought.  Any written waiver shall not be deemed a
                 continuing waiver unless specifically stated, shall
                 operate only as the specific term or condition for the
                 future or as to any act other than specifically waived.

          11.5   Notices
                 -------

                 Any notice, request, demand or other document to be given
                 hereunder shall be in writing, and shall be delivered
                 personally or sent by registered, certified or express
                 mail or facsimile followed by mail as follows:

                 If to the Company:

                        Board of Directors
                        650 Woodlawn Road West
                        Guelph, Ontario
                        Canada
                        N1K 1B8

                 If to Executive:

                        Flat 3
                        35-37 Grosvenor Square
                        London  W1X 9AE 
                        United Kingdom

                 or to such other address as either party hereto may
                 hereinafter duly give to the other.

          11.6   Severability
                 ------------

                 To the extent any provision of this Agreement shall be
                 invalid or unenforceable, it shall be considered deleted
                 herefrom and the remainder of such provision and of this
                 Agreement shall be unaffected and shall continue in full
                 force and effect.  In furtherance and not in limitation of
                 the foregoing, should the duration or geographical extent
                 of, or business activities covered by any provision of
                 this Agreement be in excess of that which is valid or
                 enforceable under applicable law, then such provision
                 shall be construed to cover only that duration, extent or
                 activities which may be validly and enforceably be
                 covered.  Executive acknowledges the uncertainty of the
                 law in this respect and expressly stipulates that this
                 Agreement be given the construction which renders its
                 provisions valid and enforceable to the maximum extent
                 (not exceeding its express terms) possible under
                 applicable law.


          IN WITNESS WHEREOF, the parties have executed this Agreement as
          of the day and year set forth above.



          ------------------------------
          F Michael P Warren



          INTERNATIONAL MUREX
          TECHNOLOGIES CORPORATION



          By:
             --------------------------------

                 Victor A Rice, on behalf of the
                 Compensation Committee 
                 and the Board of Directors



                                      EXHIBIT A
                                      ---------

                              DEFERRED COMPENSATION PLAN
                              --------------------------

          1.     At the time the Executive elects to defer compensation
                 pursuant to Section 4.3 of the Employment Agreement, the
                 Executive shall also elect the percentage of such
                 compensation to be credited from the date of deferral to
                 the date it is paid to the Executive with either (a)
                 simple interest at a rate per annum equal to the average
                 of the rates then being earned by the Company on deposits
                 with a term of ninety days or less, adjusted on the first
                 day of each calendar quarter or (b) the same rate of
                 return experienced by the common stock of the Company. 
                 The portion of the compensation deferred by the Executive
                 to which the Executive elects to have the Company common
                 stock rate of return apply shall be hypothetically
                 invested in shares of the Company's common stock based on
                 the closing price of the Company's common stock on the
                 Nasdaq National Market System, or such other exchange that
                 the Company's common stock may be listed at the time, on
                 the business day prior to the date on which the
                 compensation would otherwise be paid.  The number of
                 shares of the Company's common stock in which the
                 Executive has hypothetically invested shall be adjusted to
                 reflect stock splits, stock dividends and other capital
                 changes affecting the outstanding common stock of the
                 Company in the same manner as an equivalent number of
                 actual shares of the Company's common stock are adjusted. 
                 In addition, all cash distributions and the fair market
                 value (as determined in good faith by the Company) of any
                 property distributions with respect to shares of common
                 stock of the Company shall be reinvested in the common
                 stock of the Company based on the closing price of the
                 common stock as reported on the Nasdaq National Market
                 System, or such other exchange that the Company's common
                 stock may be listed at the time, on the business day prior
                 to the distribution.  The portion of the Executive's
                 compensation deferred hereunder and credited with simple
                 interest, together with such simple interest, shall be
                 referred to herein as "Deferred Compensation".  The
                 portion of Executive's compensation deferred hereunder and
                 credited with the rate of return of the common stock of
                 the Company shall be reflected in hypothetical shares of
                 the Company's common stock with each such share being
                 referred to herein as a "Stock Credit".  On December 31st
                 of each year during which any Deferred Compensation or
                 Stock Credits remain unpaid, the Company shall provide the
                 Executive with a statement setting forth the amount of his
                 unpaid Deferred Compensation and the number of outstanding
                 Stock Credits.

          2.     The Deferred Compensation shall be paid to Executive in a
                 lump sum following the termination of his employment with
                 the Company for any reason on the 30th day following the
                 date of termination.  The number of Stock Credits credited
                 to the Executive shall be paid to the Executive on the
                 30th date following the date of his termination, by the
                 release of common stock to the Executive."

          3.     Notwithstanding the foregoing, in the event of the
                 occurrence of an "unforeseeable emergency," as hereinafter
                 defined, Executive shall be entitled to a payment from the
                 Deferred Compensation (or release of common stock
                 representing Stock Credits) prior to the date set forth in
                 paragraph 2 of this Exhibit A of that amount reasonably
                 required to satisfy the emergency need.  As used herein,
                 "unforeseeable emergency" shall be limited to (i) severe
                 financial hardship to Executive resulting from a sudden
                 and unexpected illness or accident of Executive or of a
                 dependent of Executive, as dependent is defined in Section
                 152 of the Internal Revenue Code or any successor
                 provision thereto, (ii) loss of Executive's property due
                 to casualty, or (iii) other similar extraordinary and
                 unforeseeable circumstances arising as a result of events
                 beyond the control of Executive.  The circumstances that
                 will constitute an unforeseeable emergency will depend
                 upon the facts of each case, but, in any case, a payment
                 (or release) of all or any portion of the Deferred
                 Compensation in the event of an unforeseeable emergency
                 may not be made to the extent that such hardship is or may
                 be relieved;

                        (i)    Through reimbursement or compensation by
                 insurance or otherwise,

                        (ii)   By liquidation of Executive's assets, to the
                 extent the liquidation of such assets would not itself
                 cause severe financial hardship, or

                        (iii)  By cessation of the deferral of the payment
                 of the Deferred Compensation pursuant to paragraph 2,
                 above.

          4.     The Company's obligation to pay the Deferred Compensation
                 or release of common stock representing Stock Credits
                 constitutes a mere promise by the Company to make these
                 payments at the times specified herein.  Accordingly,
                 Executive shall have the status of a general unsecured
                 creditor with respect to the Deferred Compensation. 
                 Executive's rights to the payment of Deferred Compensation
                 or the release of common stock representing Stock Credits
                 shall not be subject in any manner to anticipation,
                 alienation, sale, transfer, assignment, pledge,
                 encumbrance, attachment, or garnishment by creditors of
                 Executive or his estate or any beneficiary of either
                 Executive or his estate.








          








          THIS AGREEMENT is made the 1st day of August, 1997 (the
          "Effective Date") by and between MUREX BIOTECH LIMITED a company
          incorporated in England and Wales (the "Company") and F MICHAEL P
          WARREN (the "Executive").

          WHEREAS, the Company and Executive previously entered into an
          Employment Agreement dated January 1, 1992; and

          WHEREAS, the term of the employment relationship created by such
          Employment Agreement has not expired; and

          WHEREAS, the Company and Executive desire to amend and restate
          the terms and conditions of their employment relationship as it
          relates to the period subsequent to 1 August, 1997.

          NOW THEREFORE, in consideration of the foregoing and the mutual
          agreements contained herein, the Company and Executive agree as
          follows:-

          1.     Employment
                 ----------

                 The Company hereby employs Executive, and Executive
                 accepts such employment and agrees to perform services for
                 the Company, for the period and upon the other terms and
                 conditions set forth in this Agreement.

          2.     Term
                 ----

                 The initial term of Executive's employment hereunder shall
                 be for a period of three (3) years, commencing as of 1
                 August 1997 (the "Commencement Date") subject to earlier
                 termination as hereinafter specified in Section 9.  At
                 each anniversary date of the Commencement Date (each a
                 "Renewal Date"), the then remaining term of this Agreement
                 shall be extended for an additional one year period in
                 addition to the then remaining term unless either party
                 hereto shall have provided written notice to the other
                 party of such non-renewal of this Agreement on or within
                 three (3) months before such Renewal Date.  In the event
                 that either party shall provide the other party with
                 written notice of non-renewal of this Agreement, this
                 Agreement shall not be extended as of any subsequent
                 Renewal Date but shall remain effective in accordance with
                 its terms (subject to termination in accordance with
                 Section 9 hereof) until the end of the then current term
                 of this Agreement.  A non-renewal of this Agreement in
                 accordance with this Section 2 shall not constitute a
                 termination of this Agreement for the purpose of Sections
                 6 or 9.

          3.     Position and Duties
                 ------------------- 

          3.1    Service with the Company
                 ------------------------

                 During the term of this Agreement, Executive shall serve
                 in such position as Executive and the Board of Directors
                 shall from time to time agree.  In such position,
                 Executive agrees to perform such executive employment
                 duties consistent with such positions as the Board of
                 Directors of the Company shall assign to him from time to
                 time.  Executive also agrees to serve, during the Term
                 hereof, as requested by the Board, and without any
                 additional compensation, as a Director of the Company and
                 as an executive officer and/or director of any
                 corporations affiliated with the Company.  The
                 compensation payable to Executive herein shall be paid by
                 the Company or by a subsidiary, holding company or
                 subsidiary of such holding company of the Company as
                 designated by Executive.

          3.2    Performance of Duties
                 ---------------------

          3.2.1  Executive agrees to serve the Company faithfully and to
                 the best of his ability and to devote the time, attention
                 and efforts necessary to advance the business and affairs
                 of the Company during the Term of this Agreement.  It is
                 understood and agreed that Executive may pursue personal
                 investments requiring time commitments that do not
                 conflict with his obligations to the Company, including
                 those in the preceding sentence.  Executive hereby
                 confirms that he is under no contractual commitments
                 inconsistent with his obligations set forth in this
                 Agreement, and that during the Term of this Agreement, he
                 shall not render or perform services, or enter into any
                 contract to do so, for any other corporation, firm, entity
                 or person which are inconsistent with the provisions of
                 this Agreement.

          3.2.2  All duties performed by Executive hereunder (other than
                 incidental duties) shall be performed at such locations in
                 the United Kingdom as the Board of Directors of the
                 Company may from time to time direct.

          4.     Compensation
                 ------------

          4.1    Base Salary
                 -----------

                 As compensation for all services to be rendered by
                 Executive under this Agreement, the Company shall pay to
                 Executive an initial base annual salary (the "Base
                 Salary") of US$107,206  which salary shall be paid in
                 semi-monthly instalments in accordance with the Company's
                 normal payroll procedures and policies.  The base salary
                 shall be increased on January 1, 1998 and on each January
                 1 thereafter by the percentage equal to the percentage
                 increase in the Consumer Price Index maintained by the
                 United States Bureau of Labour Statistics for the Atlanta,
                 Georgia metropolitan area or an equivalent index (the
                 "Index") as of January 1 of such year over the Index for
                 the immediately preceding January 1. Should the Index be
                 modified or discontinued, appropriate adjustment shall be
                 made to reflect such modification or to refer to a similar
                 index.  Additionally, Executive's Base Salary shall be
                 reviewed annually and may be increased by an amount to be
                 determined by the Compensation/Option Committee (the
                 "Committee") on the basis of Executive's performance.

          4.2    Incentive Compensation
                 ----------------------

                 In addition to the Base Salary described in Section 4.1,
                 Executive shall be eligible to receive incentive
                 compensation pursuant to the Senior Management Incentive
                 Plan as approved by the Committee or such other plans as
                 may from time to time be available.

          4.3    Deferral of Compensation
                 ------------------------

                 Executive shall be entitled to elect to defer the receipt
                 of up to seventy-five percent (75%) of his Base Salary and
                 Incentive Compensation for each calendar year during which
                 this Agreement is in effect. Executive shall make the
                 election to defer his compensation for a calendar year by
                 giving written notice to the Company of his desire to do
                 so in writing no later than December 31 of the immediately
                 preceding calendar year.  In the event that Executive
                 elects to defer the payment of any compensation due
                 hereunder in the manner contemplated by this Section 4.3,
                 the terms and conditions set forth in Exhibit A hereto
                 with respect to the circumstances under which Executive
                 shall be entitled to the payment of the deferred
                 compensation as well as the interest earned thereon and
                 the timing and method of those payments shall be
                 applicable.  Also in such event, each of the periodic
                 payments of Executive's Base Salary for any year in which
                 Executive has elected to defer receipt of a portion of his
                 Base Salary shall be reduced by the percentage amount of
                 his total Base Salary which he has elected to defer.

          4.4    Participation in Benefit Plans
                 ------------------------------

                 Executive shall also be entitled, to the extent that his
                 position, title, tenure, salary, and other qualifications
                 make him eligible, to participate in all employee benefit
                 plans or programs (including medical/dental and life
                 insurance, retirement pension, and stock option incentives
                 relating to stock in International Murex Technologies
                 Corporation) of the Company currently in existence on the
                 date hereof or as my hereafter be instituted from time to
                 time. Executives participation in any such plan or program
                 shall be subject to the provisions, rules and regulations
                 applicable thereto.

          4.5    Expenses
                 --------

                 In accordance with the Company's policies established from
                 time to time, the Company shall pay or reimburse Executive
                 for all reasonable and necessary out-of-pocket expenses
                 incurred by him in the performance of his duties under
                 this Agreement, subject to the timely presentment of
                 appropriate vouchers and receipts.

          4.6    Car Allowance
                 -------------

                 The Company shall provide Executive with a car or pay a
                 car allowance in amount recommended by the Executive
                 Committee and approved by the Committee.

          4.7    Accommodation
                 -------------

                 During the term of this Agreement and whilst Executive
                 continues to reside in the United Kingdom the Company
                 shall provide accommodation for Executive in the United
                 Kingdom of a type commensurate with the status and needs
                 of Executive and the image of the Company and its
                 associates.  The accommodation shall be provided on terms
                 to be recommended by the Executive Committee of the
                 Company and agreed in writing between the Committee and
                 Executive.

          4.8    Club and Professional Dues
                 --------------------------

                 During the term of this Agreement, Executive will be
                 entitled to reimbursement of club/professional society
                 membership dues and monthly charges and an annual physical
                 examination by the physician of Executive's choice. 
                 Amounts paid for club/professional society membership dues
                 and monthly charges shall not exceed US$5,000 annually. 
                 In the event that Executive is required to pay any tax on
                 such reimbursement, the amount to be reimbursed to
                 Executive shall be grossed up by such amount as shall
                 ensure that Executive receives the same amount as he would
                 have received had not such tax been payable.


          4.9    Double Tax Liability
                 --------------------

                 In the event that in any year during the term of this
                 Agreement Executive is required to pay income taxes on any
                 portion of his income for that year both to Canada and to
                 the United Kingdom, the Company shall pay to Executive the
                 amount which, after taking into account the taxes required
                 to be paid by Executive as a result of Executive's receipt
                 of such payment from the Company, shall cause Executive's
                 after-tax return on his income to equal the amount which
                 would have been available to Executive had no United
                 Kingdom taxes been due with respect to such income.  The
                 amounts due from the Company pursuant to the immediately
                 preceding sentence shall be determined by Executive's tax
                 return preparer, shall take into account any foreign tax
                 credits or other credits and deductions allowed against
                 his Canadian tax liability, and shall be paid to Executive
                 no later than fifteen (15) days following the date on
                 which Executive files the first tax return in which the
                 income subject to taxation in both Canada and the United
                 Kingdom is reported in any year or within fifteen (15)
                 days following the date on which the relevant taxing
                 authority determines that Executive's income is subject to
                 taxation both in Canada and in the United Kingdom, as the
                 case may be.

          4.10   Additional Benefits
                 -------------------

                 During the term of this Agreement, Executive shall be
                 entitled to participate in all present and future employee
                 benefit plans and all other compensation and benefit
                 plans, programs and structures as may from time to time be
                 made available by the Company to all other key corporate
                 executives of the Company, and on terms and conditions no
                 less favourable than those generally available to other
                 such employees.  In the event that the Company elects to
                 obtain key man life insurance insuring Executive,
                 Executive shall make himself available for the necessary
                 physical examinations and shall cooperate in all other
                 respects with the Company's efforts to obtain such
                 insurance.

          5.     Sickness
                 --------

          5.1    If Executive is absent because of sickness or injury he
                 shall report this fact forthwith to the Company and if
                 Executive is so prevented for seven or more consecutive
                 days he should provide a medical practitioners statement
                 on the eighth day and weekly thereafter so that the whole
                 period of absence is certified by such statement.
                 Immediately following his return to work after a period of
                 absence Executive shall complete a self certification form
                 available from the Company detailing the reason for his
                 absence.

          5.2    If Executive shall be absent due to sickness or injury
                 duly certified in accordance with the provisions of
                 Section 5.1, he shall be paid his full compensation
                 (including incentive compensation) for up to twelve (12)
                 weeks absence in any period of twelve consecutive months
                 and thereafter such remuneration, if any, as the board of
                 directors of the Company shall determine from time to time
                 provided that such compensation shall be inclusive of any
                 Statutory Sick Pay to which Executive is entitled under
                 the provisions of the Social Security and Housing Benefits
                 Act 1982 and any social security sickness benefit or other
                 benefit recoverable by Executive (whether or not
                 recovered) may be deducted therefrom.

          6.     Compensation upon Termination
                 -----------------------------

          6.1    In the event this Agreement is terminated pursuant to sub-
                 section 9.1(a) hereof, in addition to any benefits to
                 which Executive may then or following the termination of
                 his employment be entitled under any other applicable
                 policy or plan of the Company then the Company shall pay
                 to Executive's estate his Base Salary, incentive
                 compensation and benefits due through the effective date
                 of termination.  In the event that such termination occurs
                 on any date other than the last day of the fiscal year,
                 the incentive compensation shall be based upon the
                 performance goals achieved at the end of the fiscal year,
                 but shall be prorated based upon the number of days which
                 have elapsed in the fiscal year through the date of
                 termination.  Payment of this incentive compensation or
                 release of any stock representing incentive compensation
                 due under this Section 6.1 shall be made no later than 120
                 days following the end of the fiscal year with respect to
                 which it is being paid. Payment of all other amounts under
                 this Section 6.1 shall be made not later than the 30th day
                 following the effective date of termination. Executive's
                 estate shall be entitled to receive an amount equal to
                 twenty-four (24) times his then current monthly Base
                 Salary.

          6.2    In the event this Agreement is terminated pursuant to sub-
                 section 9.1(b)(i) hereof, Executive or his representative
                 shall be entitled to receive an amount equal to twenty
                 four (24) times his then current monthly Base Salary, less
                 any disability insurance benefits payable to Executive
                 during such twenty-four month period from disability
                 policies provided by the Company.

          6.3    In the event this Agreement is terminated pursuant to sub-
                 section 9.1(b)(ii) or (iii) hereof, Executive shall not be
                 entitled to any compensation other than his then current
                 Base Salary which has accrued through his date of
                 termination, subject to the Company's right of offset
                 based upon acts of Executive which gave rise to the
                 termination.

          6.4    In the event that Executive is terminated pursuant to sub-
                 section 9.1(c) hereof, Executive shall be entitled to a
                 severance allowance equal to the greater of (i) his Base
                 Salary for all months remaining in his then current term,
                 or (ii) his then current monthly Base Salary for twenty
                 four (24) months.

          6.5    Subject to Section 6.1, payments or the release of stock
                 representing compensation to Executive pursuant to this
                 Section 6 shall be made in either a lump sum payment or,
                 at the sole discretion of the Company in four (4) equal
                 payments within six (6) months of termination of this
                 Agreement.

          6.6    In the event that Executive is terminated pursuant to sub-
                 sections 9.1(a), 9.1(b)(i) or 9.1(c) hereof, the
                 expiration dates of Executive's options currently
                 outstanding pursuant to any of the Company's stock option
                 plans will be extended twenty four (24) months from the
                 date of such termination or such lesser period as may be
                 permitted by law or under the terms of the relevant plan.

          7.     Confidential Information
                 ------------------------

                 Except as permitted or directed by the Company's Board of
                 Directors, Executive shall not during the Term of this
                 Agreement or at any time thereafter divulge, furnish or
                 make accessible to anyone for use in any way (other than
                 in the ordinary course of the business of the Company) any
                 confidential or secret knowledge or information of the
                 Company (for the purposes of Sections 7 through 10 hereof,
                 the term "Company" shall be deemed to include any
                 subsidiary or affiliate of the Company) which Executive
                 has acquired or become acquainted with or will acquire or
                 become acquainted with prior to the termination of the
                 period of his employment by the Company, whether developed
                 by himself or by others, concerning any trade secrets,
                 confidential or secret designs, processes, formulae, plans
                 devices or material (whether or not patented or
                 patentable) directly or indirectly useful in any aspect of
                 the business of the Company, and confidential customer or
                 supplier lists of the Company, any confidential or secret
                 development or research work of the Company, or any other
                 confidential or secret aspects of the business of the
                 Company. Executive acknowledges that the above described
                 knowledge or information constitutes a unique and valuable
                 asset of the Company acquired at great time and expense by
                 the Company and its predecessors, and that any disclosure
                 or other use of such knowledge or information other than
                 for the sole benefit of the Company would be wrongful and
                 would cause irreparable harm to the Company.  Both during
                 and after the Term of this Agreement, Executive shall
                 refrain from any acts or omissions that would reduce the
                 value of the use of such knowledge or information to the
                 Company.  The foregoing obligations of confidentiality,
                 however, shall not apply to any knowledge or information
                 which is now published or which subsequently becomes
                 generally publicly known, other than as a direct or
                 indirect result of the breach of this Agreement by
                 Executive.

          8.     Non-Competition, Solicitation of Customers, Solicitation
                 --------------------------------------------------------
                 of Employees 
                 -------------

          8.1    Non-Competition
                 ---------------

                 (a)    Executive agrees that, during the period of his
                        employment hereunder and for a period of one (1)
                        year following the termination of such employment,
                        he shall not directly engage in competition with
                        the Company within the "Territory" (as hereinafter
                        defined) in any management capacity in any phase of
                        the Company's business of developing,
                        manufacturing, distributing, marketing, leasing or
                        selling any of the products which the Company is in
                        the business of developing, manufacturing,
                        distributing, marketing, leasing to others or
                        selling (the "Competitive Areas") during the Term
                        of this Agreement or which the Company has
                        definitive plans to develop, manufacture or market.

                 (b)    The "Territory" shall be that area throughout the
                        world in which the Company presently markets its
                        products.  This Agreement shall be deemed
                        automatically amended without the need of further
                        action by any party to add any new countries or
                        parts thereof where after the date hereof and prior
                        to the termination of Executive's employment the
                        Company begins to market its products and to delete
                        any countries after no Company products have been
                        sold there for a period of six months.

                 (c)    The restrictions in this Section 8 shall not apply
                        with respect to (i) a passive investment by
                        Executive of less than 5% of the outstanding shares
                        of capital stock of any corporation, or (ii)
                        employment by Executive with an entity in a
                        management capacity in an area of business which is
                        not, directly or indirectly, a Competitive Area.

          8.2    Agreement not to Solicit Customers
                 ----------------------------------

                 Executive agrees that during his employment by the Company
                 hereunder and for the two (2) year period following the
                 termination of such employment, he shall not, without the
                 prior written consent of the Company, within the
                 Territory, either directly or indirectly, on his own
                 behalf or in the service or on behalf of others, solicit,
                 divert or appropriate, or attempt to solicit, divert or
                 appropriate, to any competing business any person or
                 entity whose account with the Company was sold or serviced
                 by or under the supervision of Executive during the year
                 preceding the termination of such employment.

          8.3    Agreement not to Solicit Employees
                 ----------------------------------

                 Executive agrees that during his employment by the Company
                 hereunder and for the two (2) year period following the
                 termination of such employment, he shall not, either
                 directly or indirectly, on his own behalf or in the
                 service or on behalf of others, solicit, divert, or
                 attempt to solicit or divert any person then employed by
                 the Company.

          9.     Termination
                 -----------

          9.1    Grounds for Termination
                 -----------------------

                 This Agreement shall terminate prior to the expiration of
                 the Initial Term set forth in Section 2 or any extension
                 thereof in the event that at any time during such Initial
                 Term or any extension thereof:

                 (a)    Executive shall die; or

                 (b)    The Board of Directors of the Company shall
                        determine that:

                        (i)    Executive has become disabled; or
                        (ii)   Executive has breached this Agreement in any
                               material respect, which breach is not cured
                               by Executive or is not capable of being
                               cured (as determined in the sole discretion
                               or the Company's Board of Directors) by
                               Executive within thirty (30) days after
                               written notice of such breach is delivered
                               to Executive; or 

                        (iii)  In its sole discretion cause exists. 
                               "Cause" means (A) conduct amounting to
                               fraud, embezzlement or misappropriation as
                               against the Company, (B) the wilful and
                               knowing material breach of any fiduciary
                               duty owed to the Company as an officer of
                               the Company other than done at the direction
                               of the Board of Directors, (C) having been
                               convicted of a criminal offence which may
                               have a material adverse effect on the
                               Company or the ability of Executive to carry
                               out his duties of employment, or (D) the
                               knowing failure of Executive to follow
                               specific directives of the Board of
                               Directors of the Company consistent with his
                               duties.  If the Board of Directors
                               terminates this Agreement pursuant to this
                               Section 9.1(b)(iii), Executive will be
                               provided ninety (90) days written notice.

                 (c)    The Board of Directors of the Company shall
                        determine, in its sole discretion, that the
                        termination of this Agreement is in the best
                        interest of the Company, and in which event
                        Executive shall have no duty to mitigate his
                        damages.  If the Board of Directors terminates this
                        Agreement pursuant to this Section 9.1(c),
                        Executive will be provided ninety (90) days written
                        notice.

                 (d)    Notwithstanding any termination of this Agreement,
                        Executive, in consideration of his employment
                        hereunder to the date of such termination, shall
                        remain bound by the provisions of this Agreement
                        which specifically relate to periods, activities or
                        obligations upon or subsequent to the termination
                        of Executive's employment.

          9.2    "Disability" Defined
                 --------------------

                 The Board of Directors may determine that Executive has
                 become disabled, for the purpose of this Agreement, in the
                 event that Executive shall fail, because of illness or
                 other physical or mental incapacity, to render services of
                 the character contemplated by this Agreement for an
                 aggregate of more than twelve (12) weeks during any twelve
                 (12) month period.

          9.3    Surrender of Records and Property
                 ---------------------------------

                 Upon termination of his employment with the Company,
                 Executive shall deliver promptly to the Company all
                 records, manuals, books, blank forms, documents, letters,
                 memoranda, notes, notebooks, reports, data, tables,
                 calculations or copies thereof, which are the property of
                 the Company and which relate in any way to the business,
                 products, practices or techniques of the Company, and all
                 other property, trade secrets and confidential information
                 of the Company, including, but not limited to, all
                 documents which in whole or in part contain any trade
                 secrets or confidential information of the Company, which
                 in any of these cases are in his possession or under this
                 control.

          10.    Assignment and Enurement
                 ------------------------

                 This Agreement shall enure to the benefit of and be
                 binding upon the parties hereto and their respective
                 heirs, successors, administrators, and permitted assigns. 
                 The Company may, without the consent of Executive, assign
                 its rights and obligations under this Agreement to any
                 corporation, firm or other business entity with or into
                 which the Company may merge or consolidate, or to which
                 the Company may sell or transfer all or substantially all
                 of its assets or of which 50% or more of the equity
                 investment and of the voting control is owned, directly or
                 indirectly, by, or is under common ownership with, the
                 Company; provided, however, that if the assignee was not
                 previously part of a consolidated group with the Company,
                 Executive will receive payments and benefits as outlined
                 in Exhibit B attached hereto and incorporated herein.

          11.    Injunctive Relief
                 -----------------

                 Executive agrees that it would be difficult to compensate
                 the Company fully for damages for any violation of the
                 provisions of this Agreement, including without limitation
                 the provisions of Section 7, 8 and 9.3.  Accordingly,
                 Executive specifically agrees that the Company shall be
                 entitled to temporary and permanent injunctive relief to
                 enforce the provisions of this Agreement.  This provision
                 with respect to injunctive relief shall not, however,
                 diminish the right of the Company to claim and recover
                 damages in addition to injunctive relief.

          12.    Miscellaneous
                 -------------

          12.1   Governing Law
                 -------------

                 This Agreement is made under and shall be governed by and
                 construed in accordance with the laws of the Province of
                 Ontario subject to any principles of conflict of laws.


          12.2   Prior Agreements
                 ----------------

                 This Agreement contains the entire agreement of the
                 parties relating to the subject matter hereof and
                 supersedes all prior agreements and understandings with
                 respect to such subject matter, and the parties hereto
                 have made no agreements, representations or warranties
                 relating to the subject matter of this Agreement which are
                 not set forth herein.

          12.3   Amendments
                 ----------

                 No amendment or modification of this Agreement shall be
                 deemed effective unless made in writing signed by the
                 party against whom enforcement of the waiver or estoppel
                 is sought.  Any written waiver shall not be deemed a
                 continuing waiver unless specifically stated, shall
                 operate only as to the specific term or condition for the
                 future or as to any act other than that that specifically
                 waived.

          12.4   Notices
                 -------

                 Any notice, request, demand or other document to be given
                 hereunder shall be in writing, and shall be delivered
                 personally or sent by registered mail or facsimile
                 followed by mail as follows:

                        If to the Company:

                        Murex Biotech Limited
                        Central Road
                        Temple Hill
                        Dartford
                        Kent  DA1 5LR

                        If to Executive:

                        Flat 3
                        35-37 Grosvenor Square
                        London W1X 9AE

                 or to such other address as either party hereto may
                 hereinafter duly give to the other.


          12.5   Severability
                 ------------

                 To the extent any provision of this Agreement shall be
                 invalid or unenforceable, it shall be considered deleted
                 herefrom and the remainder of such provision and of this
                 Agreement shall be unaffected and shall continue in full
                 force and effect.  In furtherance and not in limitation of
                 the foregoing, should the duration or geographical extent
                 of, or business activities covered by any provision of
                 this Agreement be in excess of that which is valid or
                 enforceable under applicable law, then such provision
                 shall be construed to cover only that duration, extent or
                 activities which may validly and enforceably be covered. 
                 Executive acknowledges the uncertainty of the law in this
                 respect and expressly stipulates that this Agreement be
                 give the construction which renders its provisions valid
                 and enforceable to the maximum extent (not exceeding its
                 express terms) possible under applicable law.

          12.6   Withholding Taxes
                 -----------------

                 The Company may withhold from any benefits payable under
                 this Agreement all federal, state, city and other taxes as
                 shall be required pursuant to any law or governmental
                 regulation or ruling.

          IN WITNESS WHEREOF, the parties have executed this Agreement the
          day and year set forth above.



                                       SCHEDULE
                                       --------

                           Statement of Terms of Employment
                           --------------------------------


          1.     Amplification of Terms of Employment

          (a)    Name of Employer:    Murex Biotech Limited

          (b)    Address of Employer:  Central Road, Temple Hill, Dartford,
                 Kent DA1 5LR

          (c)    Name of Executive: Frederic Michael Patrick Warren

          (d)    Address of Executive: Flat 3, 35-37 Grosvenor Square,
                 London W1X 9AE

          (e)    Date of Commencement of Employment with the Company: 
                 January 1 1992

          (f)    Compensation: See Section 4

          (g)    Notice:  See Section 9

          (h)    Job Title:  See Section 3

          2.     In accordance with Section 1(3) of the Employment
                 Protection (Consolidation) Act 1978 the following terms of
                 the Executive's employment apply on the date of the
                 agreement to which this is a schedule:

          (a)    Hours of Work:  there are no fixed hours of work provided
                 that Executive shall be required to devote not less than
                 25 hours per week to the performance of his duties under
                 the Agreement.

          (b)    Holidays:  Executive is not entitled to any paid holidays
                 under the Agreement other than Bank Holidays

          (c)    Sickness or injury:  see Section 5 of the Agreement

          (d)    Other benefits:  see Section 4 of the Agreement

          3.     The following information is supplied pursuant to the
                 Employment Protection (Consolidation) Act 1978 (as may be
                 amended from time to time)

          (a)    Disciplinary Rules:  there are no formal disciplinary
                 procedures applicable to this employment;

          (b)    Grievance Procedure:  all grievances relating to the
                 employment under the agreement to which this is a schedule
                 should be reported to the board of directors of the
                 Company;

          (c)    A Contracting Out certificate is not in force in respect
                 of this employment.




          Signed by                   )
          VICTOR A RICE               )
          for and on behalf of        )
          MUREX BIOTECH               )
          LIMITED                     )
          in the presence of:-        )




          Signed by F MICHAEL P       )
          WARREN in the presence      )
          of:-                        )





                                      EXHIBIT A
                                      ---------

                              DEFERRED COMPENSATION PLAN
                              --------------------------

                 1.     At the time the Executive elects to defer
          compensation pursuant to Section 4.3 of the Employment Agreement,
          the Executive shall also elect the percentage of such
          compensation to be credited from the date of deferral to the date
          it is paid to the Executive with either (a) simple interest at a
          rate per annum equal to the average of the rates then being
          earned by the Company on deposits with a term of ninety days or
          less, adjusted on the first day of each calendar quarter or (b)
          the same rate of return experienced by the common stock of the
          Company.  The portion of the compensation deferred by the
          Executive to which the Executive elects to have the Company
          common stock rate of return apply shall be hypothetically
          invested in shares of the Company's common stock based on the
          closing price of the Company's common stock on the Nasdaq
          National Market System, or such other exchange that the Company's
          common stock may be listed at the time, on the business day prior
          to the date on which the compensation would otherwise be paid. 
          The number of shares of the Company's common stock in which the
          Executive has hypothetically invested shall be adjusted to
          reflect stock splits, stock dividends and other capital changes
          affecting the outstanding common stock of the Company in the same
          manner as an equivalent number of actual shares of the Company's
          common stock are adjusted.  In addition, all cash distributions
          and the fair market value (as determined in good faith by the
          Company) of any property distributions with respect to shares of
          common stock of the Company shall be reinvested in the common
          stock of the Company based on the closing price of the common
          stock as reported on the Nasdaq National Market System, or such
          other exchange that the Company's common stock may be listed at
          the time, on the business day prior to the distribution.  The
          portion of the Executive's compensation deferred hereunder and
          credited with simple interest, together with such simple
          interest, shall be referred to herein as "Deferred Compensation". 
          The portion of Executive's compensation deferred hereunder and
          credited with the rate of return of the common stock of the
          Company shall be reflected in hypothetical shares of the
          Company's common stock with each such share being referred to
          herein as a "Stock Credit".  On December 31st of each year during
          which any Deferred Compensation or Stock Credits remain unpaid,
          the Company shall provide the Executive with a statement setting
          forth the amount of his unpaid Deferred Compensation and the
          number of outstanding Stock Credits.

                 2.     The Deferred Compensation shall be paid to
          Executive in a lump sum following the termination of his
          employment with the Company for any reason on the 30th day
          following the date of termination.  The number of Stock Credits
          credited to the Executive shall be paid to the Executive on the
          30th date following the date of his termination, by the release
          of common stock to the Executive."

                 3.     Notwithstanding the foregoing, in the event of the
          occurrence of an "unforeseeable emergency," as hereinafter
          defined, Executive shall be entitled to a payment from the
          Deferred Compensation (or release of common stock representing
          Stock Credits) prior to the date set forth in paragraph 2 of this
          Exhibit A of that amount reasonably required to satisfy the
          emergency need.  As used herein, "unforeseeable emergency" shall
          be limited to (i) severe financial hardship to Executive
          resulting from a sudden and unexpected illness or accident of
          Executive or of a dependent of Executive, as dependent is defined
          in Section 152 of the Internal Revenue Code or any successor
          provision thereto, (ii) loss of Executive's property due to
          casualty, or (iii) other similar extraordinary and unforeseeable
          circumstances arising as a result of events beyond the control of
          Executive.  The circumstances that will constitute an
          unforeseeable emergency will depend upon the facts of each case,
          but, in any case, a payment (or release) of all or any portion of
          the Deferred Compensation in the event of an unforeseeable
          emergency may not be made to the extent that such hardship is or
          may be relieved;

                        (i)    Through reimbursement or compensation by
                 insurance or otherwise,

                        (ii)   By liquidation of Executive's assets, to the
                 extent the liquidation of such assets would not itself
                 cause severe financial hardship, or

                        (iii)  By cessation of the deferral of the payment
                 of the Deferred Compensation pursuant to paragraph 2,
                 above.

                 4.     The Company's obligation to pay the Deferred
          Compensation or release of common stock representing Stock
          Credits constitutes a mere promise by the Company to make these
          payments at the times specified herein.  Accordingly, Executive
          shall have the status of a general unsecured creditor with
          respect to the Deferred Compensation.  Executive's rights to the
          payment of Deferred Compensation or the release of common stock
          representing Stock Credits shall not be subject in any manner to
          anticipation, alienation, sale, transfer, assignment, pledge,
          encumbrance, attachment, or garnishment by creditors of Executive
          or his estate or any beneficiary of either Executive or his
          estate.






          THIS AGREEMENT is made the 1st day of August, 1997 (the
          "Effective Date") by and between MUREX DIAGNOSTICS CORPORATION a
          company incorporated under the laws of Barbados  (the "Company")
          and F MICHAEL P WARREN ("Executive")

          WHEREAS, the Company and Executive previously entered into an
          Employment Agreement dated January 1, 1992; and

          WHEREAS, the term of the employment relationship created by such
          Employment Agreement has not expired; and

          WHEREAS, the Company and Executive desire to amend and restate
          the terms and conditions of their employment relationship as it
          relates to the period subsequent to 1 August, 1997.

          NOW THEREFORE, in consideration of the foregoing and the mutual
          agreements contained herein, the Company and Executive agree as
          follows:-

          1.     Employment
                 ----------

                 The Company hereby employs Executive, and Executive
                 accepts such employment and agrees to perform services for
                 the Company, for the period and upon the other terms and
                 conditions set forth in this Agreement.

          2.     Term
                 ----

                 The initial term of Executive's employment hereunder shall
                 be for a period of three (3) years, commencing as of 1
                 August 1997 (the "Commencement Date") subject to earlier
                 termination as hereinafter specified in Section 8.  At
                 each anniversary date of the Commencement Date (each a
                 "Renewal Date"), the then remaining term of this Agreement
                 shall be extended for an additional one year period in
                 addition to the then remaining term unless either party
                 hereto shall have provided written notice to the other
                 party of such non-renewal of this Agreement on or within
                 three (3) months before such Renewal Date.  In the event
                 that either party shall provide the other party with
                 written notice of non-renewal of this Agreement, this
                 Agreement shall not be extended as of any subsequent
                 Renewal Date but shall remain effective in accordance with
                 its terms (subject to termination in accordance with
                 Section 8 hereof) until the end of the then current term
                 of this Agreement.  A non-renewal of this Agreement in
                 accordance with this Section 2 shall not constitute a
                 termination of this Agreement for the purpose of Sections
                 5 or 8.

          3.     Position and Duties
                 -------------------

          3.1    Service with the Company
                 ------------------------

                 During the term of this Agreement, Executive shall serve
                 in such position as Executive and the Board of Directors
                 shall from time to time agree.  In such position,
                 Executive agrees to perform such executive employment
                 duties consistent with such positions as the Board of
                 Directors of the Company shall assign to him from time to
                 time.  Executive also agrees to serve, during the Term
                 hereof, as requested by the Board, and without any
                 additional compensation, as a Director of the Company and
                 as an executive officer and/or director of any
                 corporations affiliated with the Company.  The
                 compensation payable to Executive herein shall be paid by
                 the Company or by a subsidiary, holding company or
                 subsidiary of such holding company of the Company as
                 designated by Executive.

          3.2    Performance of Duties
                 ---------------------

          3.2.1  Executive agrees to serve the Company faithfully and to
                 the best of his ability and to devote the time, attention
                 and efforts necessary to advance the business and affairs
                 of the Company during the Term of this Agreement.  It is
                 understood and agreed that Executive may pursue personal
                 investments requiring time commitments that do not
                 conflict with his obligations to the Company, including
                 those in the preceding sentence.  Executive hereby
                 confirms that he is under no contractual commitments
                 inconsistent with his obligations set forth in this
                 Agreement, and that during the Term of this Agreement, he
                 shall not render or perform services, or enter into any
                 contract to do so, for any other corporation, firm, entity
                 or person which are inconsistent with the provisions of
                 this Agreement.

          3.2.2  All duties performed by Executive under the terms of this
                 Agreement (other than incidental duties) shall be
                 performed at such locations outside the United Kingdom and
                 Canada as the Board of the Directors of the Company may
                 from time to time direct.

          4.     Compensation
                 ------------

          4.1    Base Salary
                 -----------

                 As compensation for all services to be rendered by
                 Executive under this Agreement, the Company shall pay to
                 Executive an initial base annual salary (the "Base
                 Salary") of US$119,118 which salary shall be paid in semi-
                 monthly instalments in accordance with the Company's
                 normal payroll procedures and policies.  The base salary
                 shall be increased on January 1, 1998 and on each January
                 1 thereafter by the percentage equal to the percentage
                 increase in the Consumer Price Index maintained by the
                 United States Bureau of Labour Statistics for the Atlanta,
                 Georgia metropolitan area or an equivalent index (the
                 "Index") as of January 1 of such year over the Index for
                 the immediately preceding January 1. Should the Index be
                 modified or discontinued, appropriate adjustment shall be
                 made to reflect such modification or to refer to a similar
                 index.  Additionally, Executive's Base Salary shall be
                 reviewed annually and may be increased by an amount to be
                 determined by the Compensation/Option Committee (the
                 "Committee") on the basis of Executive's performance.

          4.2    Incentive Compensation
                 ----------------------

                 In addition to the Base Salary described in Section 4.1,
                 Executive shall be eligible to receive incentive
                 compensation pursuant to the Senior Management Incentive
                 Plan as agreed by the Committee or such other plans as may
                 from time to time be available.

          4.3    Deferral of Compensation
                 ------------------------

                 Executive shall be entitled to elect to defer the receipt
                 of up to seventy-five percent (75%) of his Base Salary and
                 Incentive Compensation for each calendar year during which
                 this Agreement is in effect. Executive shall make the
                 election to defer his compensation for a calendar year by
                 giving written notice to the Company of his desire to do
                 so in writing no later than December 31 of the immediately
                 preceding calendar year.  In the event that Executive
                 elects to defer the payment of any compensation due
                 hereunder in the manner contemplated by this Section 4.3,
                 the terms and conditions set forth in Exhibit A hereto
                 with respect to the circumstances under which Executive
                 shall be entitled to the payment of the deferred
                 compensation as well as the interest earned thereon and
                 the timing and method of those payments shall be
                 applicable.  Also in such event, each of the periodic
                 payments of Executive's Base Salary for any year in which
                 Executive has elected to defer receipt of a portion of his
                 Base Salary shall be reduced by the percentage amount of
                 his total Base Salary which he has elected to defer.

          4.4    Participation in Benefit Plans
                 ------------------------------

                 Executive shall also be entitled, to the extent that his
                 position, title, tenure, salary, age, health and other
                 qualifications make him eligible, to participate in all
                 employee benefit plans or programs (including
                 medical/dental and life insurance, retirement pension, and
                 stock option incentives relating to stock in International
                 Murex Technologies Corporation) of the Company currently
                 in existence on the date hereof or as may hereafter be
                 instituted from time to time. Executives participation in
                 any such plan or program shall be subject to the
                 provisions, rules and regulations applicable thereto.

          4.5    Expenses
                 --------

                 In accordance with the Company's policies established from
                 time to time, the Company shall pay or reimburse Executive
                 for all reasonable and necessary out-of-pocket expenses
                 incurred by him in the performance of his duties under
                 this Agreement, subject to the timely presentment of
                 appropriate vouchers and receipts.

          4.6    Double Tax Liability
                 --------------------

                 In the event that in any year during the term of this
                 Agreement Executive is required to pay income taxes on any
                 portion of his income for that year both to Canada and to
                 the United Kingdom, the Company shall pay to Executive the
                 amount which, after taking into account the taxes required
                 to be paid by Executive as a result of Executive's receipt
                 of such payment from the Company, shall cause Executive's
                 after-tax return on his income to equal the amount which
                 would have been available to Executive had no United
                 Kingdom taxes been due with respect to such income.  The
                 amounts due from the Company pursuant to the immediately
                 preceding sentence shall be determined by Executive's tax
                 return preparer, shall take into account any foreign tax
                 credits or other credits and deductions allowed against
                 his Canadian tax liability, and shall be paid to Executive
                 no later than fifteen days following the date on which
                 Executive files the first tax return in which the income
                 subject to taxation in both Canada and the United Kingdom
                 is reported in any year, or within fifteen days following
                 the date on which the relevant taxing authority determines
                 that Executive's income is subject to taxation both in
                 Canada and in the United Kingdom, as the case may be.

          4.7    Additional Benefits
                 -------------------

                 During the term of this Agreement, Executive shall be
                 entitled to participate in all present and future employee
                 benefit plans and all other compensation and benefit
                 plans, programs and structures as may from time to time be
                 made available by the Company to all other key corporate
                 executives of the Company, and on terms and conditions no
                 less favourable than those generally available to other
                 such employees.  In the event that the Company elects to
                 obtain key man life insurance insuring Executive,
                 Executive shall make himself available for the necessary
                 physical examinations and shall cooperate in all other
                 respects with the Company's efforts to obtain such
                 insurance.

          5.     Compensation upon Termination
                 -----------------------------

                 (a)    In the event this Agreement is terminated pursuant
                        to sub-section 8.1(a) hereof, in addition to any
                        benefits to which Executive may then or following
                        the termination of his employment be entitled under
                        any other applicable policy or plan of the Company
                        then in effect (including basic life insurance
                        which coverage equals two times annual salary, and
                        survivor benefits which provide Accidental Death
                        and Dismemberment for each employee at two times
                        the annual salary), the Company shall pay to
                        Executive's estate his Base Salary, incentive
                        compensation and benefits due through the effective
                        date of termination.  In the event that such
                        termination occurs on any date other than the last
                        day of the fiscal year, the incentive compensation
                        shall be based upon the performance goals achieved
                        at the end of the fiscal year, but shall be
                        prorated based upon the number of days which have
                        elapsed in the fiscal year through the date of
                        termination. Payment of this incentive compensation
                        or release of any stock representing incentive
                        compensation due under this Section 5(a) shall be
                        made no later than 120 days following the end of
                        the fiscal year with respect to which it is being
                        paid. Payment of all other amounts  under this
                        Section 5(a) shall be made not later than the 30th
                        day following the effective date of termination. 
                        Executive's estate shall be entitled to receive an
                        amount equal to twenty-four (24) times his then
                        current monthly Base Salary.

                 (b)    In the event this Agreement is terminated pursuant
                        to sub-section 8.1(b)(i) hereof, Executive or his
                        representative shall be entitled to receive an
                        amount equal to twenty four (24) times his then
                        current monthly Base Salary, less any disability
                        insurance benefits payable to Executive during such
                        twenty-four month period from disability policies
                        provided by the Company.

                 (c)    In the event this Agreement is terminated pursuant
                        to sub-section 8.1(b)(ii) or (iii) hereof,
                        Executive shall not be entitled to any compensation
                        other than his then current Base Salary which has
                        accrued through his date of termination, subject to
                        the Company's right of offset based upon acts of
                        Executive which gave rise to the termination.

                 (d)    In the event this Agreement is terminated pursuant
                        to sub-section 8.1(c) hereof, Executive shall be
                        entitled to a severance allowance equal to the
                        greater of (i) his Base Salary for all months
                        remaining in his then current term, or (ii) his
                        then current monthly Base Salary for twenty four
                        (24) months.

                 (e)    Subject to sub-section 5(a) payments or the release
                        of stock representing compensation to Executive
                        pursuant to this Section 6 shall be made in either
                        a lump sum payment or, at the sole discretion of
                        the Company in four (4) equal payments, within six
                        (6) months of termination of this Agreement.

                 (f)    In the event that Executive is terminated pursuant
                        to Subsections 8.1(a), 8.1(b)(i) or 8.1(c) hereof,
                        the expiration dates of Executive's options
                        currently outstanding pursuant to any of the
                        Company's stock option plans will be extended
                        twenty-four (24) months from the date of such
                        termination.

          6.     Confidential Information
                 ------------------------

                 Except as permitted or directed by the Company's Board of
                 Directors, Executive shall not during the Term of this
                 Agreement or at any time thereafter divulge, furnish or
                 make accessible to anyone for use in any way (other than
                 in the ordinary course of the business of the Company) any
                 confidential or secret knowledge or information of the
                 Company (for the purposes of Sections 7 through 9 hereof,
                 the term "Company" shall be deemed to include any
                 subsidiary or affiliate of the Company) which Executive
                 has acquired or become acquainted with or will acquire or
                 become acquainted with prior to the termination of the
                 period of his employment by the Company, whether developed
                 by himself or by others, concerning any trade secrets,
                 confidential or secret designs, processes, formulae, plans
                 devices or material (whether or not patented or
                 patentable) directly or indirectly useful in any aspect of
                 the business of the Company, and confidential customer or
                 supplier lists of the Company, any confidential or secret
                 development or research work of the Company, or any other
                 confidential or secret aspects of the business of the
                 Company. Executive acknowledges that the above described
                 knowledge or information constitutes a unique and valuable
                 asset of the Company acquired at great time and expense by
                 the Company and its predecessors, and that any disclosure
                 or other use of such knowledge or information other than
                 for the sole benefit of the Company would be wrongful and
                 would cause irreparable harm to the Company.  Both during
                 and after the Term of this Agreement, Executive shall
                 refrain from any acts or omissions that would reduce the
                 value of the use of such knowledge or information to the
                 Company.  The foregoing obligations of confidentiality,
                 however, shall not apply to any knowledge or information
                 which is now published or which subsequently becomes
                 generally publicly known, other than as a direct or
                 indirect result of the breach of this Agreement by
                 Executive.

          7.     Non-Competition, Solicitation of Customers, Solicitation
                 --------------------------------------------------------
                 of Employees 
                 ------------

          7.1    Non-Competition
                 ---------------

                 (a)    Executive agrees that, during the period of his
                        employment hereunder and for a period of one (1)
                        year following the termination of such employment,
                        he shall not directly engage in competition with
                        the Company within the "Territory" (as hereinafter
                        defined) in any management capacity in any phase of
                        the Company's business of developing,
                        manufacturing, distributing, marketing, leasing or
                        selling any of the products which the Company is in
                        the business of developing, manufacturing,
                        distributing, marketing, leasing to others or
                        selling (the "Competitive Areas") during the Term
                        of this Agreement or which the Company has
                        definitive plans to develop, manufacture or market.

                 (b)    The "Territory" shall be that area throughout the
                        world in which the Company presently markets its
                        products.  This Agreement shall be deemed
                        automatically amended without the need of further
                        action by any party to add any new countries or
                        parts thereof where after the date hereof and prior
                        to the termination of Executive's employment the
                        Company begins to market its products and to delete
                        any countries after no Company products have been
                        sold there for a period of six months.

                 (c)    The restrictions in this Section 7 shall not apply
                        with respect to (i) a passive investment by
                        Executive of less than 5% of the outstanding shares
                        of capital stock of any corporation, or (ii)
                        employment by Executive with an entity in a
                        management capacity in an area of business which is
                        not, directly or indirectly, a Competitive Area.

          7.2    Agreement not to Solicit Customers
                 ----------------------------------

                 Executive agrees that during his employment by the Company
                 hereunder and for the two (2) year period following the
                 termination of such employment, he shall not, without the
                 prior written consent of the Company, within the
                 Territory, either directly or indirectly, on his own
                 behalf or in the service or on behalf of others, solicit,
                 divert or appropriate, or attempt to solicit, divert or
                 appropriate, to any competing business any person or
                 entity whose account with the Company was sold or serviced
                 by or under the supervision of Executive during the year
                 preceding the termination of such employment.

          7.3    Agreement not to Solicit Employees
                 ----------------------------------

                 Executive agrees that during his employment by the Company
                 hereunder and for the two (2) year period following the
                 termination of such employment, he shall not, either
                 directly or indirectly, on his own behalf or in the
                 service or on behalf of others, solicit, divert, or
                 attempt to solicit or divert any person then employed by
                 the Company.

          8.     Termination
                 -----------

          8.1    Grounds for Termination
                 -----------------------

                 This Agreement shall terminate prior to the expiration of
                 the Initial Term set forth in Section 2 or any extension
                 thereof in the event that at any time during such Initial
                 Term or any extension thereof:

                 (a)    Executive shall die; or

                 (b)    The Board of Directors of the Company shall
                        determine that:

                        (i)    Executive has become disabled;

                        (ii)   Executive has breached this Agreement in any
                               material respect, which breach is not cured
                               by Executive or is not capable of being
                               cured (as determined in the sole discretion
                               or the Company's Board of Directors) by
                               Executive within thirty (30) days after
                               written notice of such breach is delivered
                               to Executive; or

                        (iii)  In its sole discretion cause exists. 
                               "Cause" means (A) conduct amounting to
                               fraud, embezzlement or misappropriation as
                               against the Company, (B) the wilful and
                               knowing material breach of any fiduciary
                               duty owed to the Company as an officer of
                               the Company other than done at the direction
                               of the Board of Directors, (C) having been
                               convicted of a criminal offence which may
                               have a material adverse effect on the
                               Company or the ability of Executive to carry
                               out his duties of employment, or (D) the
                               knowing failure of Executive to follow
                               specific directives of the Board of
                               Directors of the Company consistent with his
                               duties.  If the Board of Directors terminate
                               this Agreement pursuant to Section
                               8.1(b)(iii), Executive will be provided
                               ninety (90) days written notice.

                 (c)    The Board of Directors of the Company shall
                        determine, in its sole discretion, that the
                        termination of this Agreement is in the best
                        interest of the Company, and in which event
                        Executive shall have no duty to mitigate his
                        damages.  If the Board of Directors terminate this
                        Agreement pursuant to this Section 8.1(c),
                        Executive will be provided ninety (90) days written
                        notice.

                 (d)    Notwithstanding any termination of this Agreement,
                        Executive, in consideration of his employment
                        hereunder to the date of such termination, shall
                        remain bound by the provisions of this Agreement
                        which specifically relate to periods, activities or
                        obligations upon or subsequent to the termination
                        of Executive's employment.

          8.2    "Disability" Defined
                 --------------------

                 The Board of Directors may determine that Executive has
                 become disabled, for the purpose of this Agreement, in the
                 event that Executive shall fail, because of illness or
                 other physical or mental incapacity, to render services of
                 the character contemplated by this Agreement for an
                 aggregate of more than twelve (12) weeks during any twelve
                 (12) month period.

          8.3    Surrender of Records and Property
                 ---------------------------------

                 Upon termination of his employment with the Company,
                 Executive shall deliver promptly to the Company all
                 records, manuals, books, blank forms, documents, letters,
                 memoranda, notes, notebooks, reports, data, tables,
                 calculations or copies thereof, which are the property of
                 the Company and which relate in any way to the business,
                 products, practices or techniques of the Company, and all
                 other property, trade secrets and confidential information
                 of the Company, including, but not limited to, all
                 documents which in whole or in part contain any trade
                 secrets or confidential information of the Company, which
                 in any of these cases are in his possession or under this
                 control.

          9.     Assignment and Enurement
                 ------------------------

                 This Agreement shall enure to the benefit of and be
                 binding upon the parties hereto and their respective
                 heirs, successors, administrators, and permitted assigns. 
                 The Company may, without the consent of Executive, assign
                 its rights and obligations under this Agreement to any
                 corporation, firm or other business entity with or into
                 which the Company may merge or consolidate, or to which
                 the Company may sell or transfer all or substantially all
                 of its assets or of which 50% or more of the equity
                 investment and of the voting control is owned, directly or
                 indirectly, by, or is under common ownership with, the
                 Company; provided, however, that if the assignee was not
                 previously part of a consolidated group with the Company,
                 Executive will receive payments and benefits as outlined
                 in Exhibit B attached hereto and incorporated herein.

          10.    Injunctive Relief
                 -----------------

                 Executive agrees that it would be difficult to compensate
                 the Company fully for damages for any violation of the
                 provisions of this Agreement, including without limitation
                 the provisions of Sections 6, 7 and 8.3.  Accordingly,
                 Executive specifically agrees that the Company shall be
                 entitled to temporary and permanent injunctive relief to
                 enforce the provisions of this Agreement.  This provision
                 with respect to injunctive relief shall not, however,
                 diminish the right of the Company to claim and recover
                 damages in addition to injunctive relief.

          11.    Miscellaneous
                 -------------

          11.1   Governing Law
                 -------------

                 This Agreement is made under and shall be governed by and
                 construed in accordance with the laws of the Province of
                 Ontario subject to any principles of conflict of laws.

          11.2   Prior Agreements
                 ----------------

                 This Agreement contains the entire agreement of the
                 parties relating to the subject matter hereof and
                 supersedes all prior agreements and understandings with
                 respect to such subject matter, and the parties hereto
                 have made no agreements, representations or warranties
                 relating to the subject matter of this Agreement which are
                 not set forth herein.

          11.3   Withholding Taxes
                 -----------------

                 The Company may withhold from any benefits payable under
                 this Agreement all federal, state, city and other taxes as
                 shall be required pursuant to any law or governmental
                 regulation or ruling.

          11.4   Amendments
                 ----------

                 No amendment or modification of this Agreement shall be
                 deemed effective unless made in writing signed by the
                 party against whom enforcement of the waiver or estoppel
                 is sought.  Any written waiver shall not be deemed a
                 continuing waiver unless specifically stated, shall
                 operate only as to the specific term or condition for the
                 future or as to any act other than that specifically
                 waived.

          11.5   Notices
                 -------

                 Any notice, request, demand or other document to be given
                 hereunder shall be in writing, and shall be delivered
                 personally or sent by registered mail or facsimile
                 followed by mail as follows:

                 If to the Company:

                        Murex Diagnostics Corporation
                        White Park House
                        White Park Road
                        Bridgetown 
                        Barbados

                        FAO  The Chairman

                 If to Executive:
                   
                        Flat 3
                        35-37 Grosvenor Square
                        London  W1X 9AE

                 or to such other address as either party hereto may
                 hereinafter duly give to the other.

          11.6   Severability
                 ------------

                 To the extent any provision of this Agreement shall be
                 invalid or unenforceable, it shall be considered deleted
                 herefrom and the remainder of such provision and of this
                 Agreement shall be unaffected and shall continue in full
                 force and effect.  In furtherance and not in limitation of
                 the foregoing, should the duration or geographical extent
                 of, or business activities covered by any provision of
                 this Agreement be in excess of that which is valid or
                 enforceable under applicable law, then such provision
                 shall be construed to cover only that duration, extent or
                 activities which may validly and enforceably be covered. 
                 Executive acknowledges the uncertainty of the law in this
                 respect and expressly stipulates that this Agreement be
                 give the construction which renders its provisions valid
                 and enforceable to the maximum extent (not exceeding its
                 express terms) possible under applicable law.



                            (Signatures on following page)


          IN WITNESS WHEREOF, the parties have executed this Agreement as
          of the day and year set forth above.


          Signed by                   )/s/ Victor A Rice
          VICTOR A RICE               )
          for and on behalf of        )
          MUREX DIAGNOSTICS           )
          CORPORATION in the          )
          presence of:-               )







          Signed by F MICHAEL         )/s/ F Michael P Warren
          P WARREN in the             )
          presence of:-               )







                                      EXHIBIT A
                                      ---------

                              DEFERRED COMPENSATION PLAN
                              --------------------------

                 1.     At the time the Executive elects to defer
          compensation pursuant to Section 4.3 of the Employment Agreement,
          the Executive shall also elect the percentage of such
          compensation to be credited from the date of deferral to the date
          it is paid to the Executive with either (a) simple interest at a
          rate per annum equal to the average of the rates then being
          earned by the Company on deposits with a term of ninety days or
          less, adjusted on the first day of each calendar quarter or (b)
          the same rate of return experienced by the common stock of the
          Company.  The portion of the compensation deferred by the
          Executive to which the Executive elects to have the Company
          common stock rate of return apply shall be hypothetically
          invested in shares of the Company's common stock based on the
          closing price of the Company's common stock on the Nasdaq
          National Market System, or such other exchange that the Company's
          common stock may be listed at the time, on the business day prior
          to the date on which the compensation would otherwise be paid. 
          The number of shares of the Company's common stock in which the
          Executive has hypothetically invested shall be adjusted to
          reflect stock splits, stock dividends and other capital changes
          affecting the outstanding common stock of the Company in the same
          manner as an equivalent number of actual shares of the Company's
          common stock are adjusted.  In addition, all cash distributions
          and the fair market value (as determined in good faith by the
          Company) of any property distributions with respect to shares of
          common stock of the Company shall be reinvested in the common
          stock of the Company based on the closing price of the common
          stock as reported on the Nasdaq National Market System, or such
          other exchange that the Company's common stock may be listed at
          the time, on the business day prior to the distribution.  The
          portion of the Executive's compensation deferred hereunder and
          credited with simple interest, together with such simple
          interest, shall be referred to herein as "Deferred Compensation". 
          The portion of Executive's compensation deferred hereunder and
          credited with the rate of return of the common stock of the
          Company shall be reflected in hypothetical shares of the
          Company's common stock with each such share being referred to
          herein as a "Stock Credit".  On December 31st of each year during
          which any Deferred Compensation or Stock Credits remain unpaid,
          the Company shall provide the Executive with a statement setting
          forth the amount of his unpaid Deferred Compensation and the
          number of outstanding Stock Credits.

                 2.     The Deferred Compensation shall be paid to
          Executive in a lump sum following the termination of his
          employment with the Company for any reason on the 30th day
          following the date of termination.  The number of Stock Credits
          credited to the Executive shall be paid to the Executive on the
          30th date following the date of his termination, by the release
          of common stock to the Executive."

                 3.     Notwithstanding the foregoing, in the event of the
          occurrence of an "unforeseeable emergency," as hereinafter
          defined, Executive shall be entitled to a payment from the
          Deferred Compensation (or release of common stock representing
          Stock Credits) prior to the date set forth in paragraph 2 of this
          Exhibit A of that amount reasonably required to satisfy the
          emergency need.  As used herein, "unforeseeable emergency" shall
          be limited to (i) severe financial hardship to Executive
          resulting from a sudden and unexpected illness or accident of
          Executive or of a dependent of Executive, as dependent is defined
          in Section 152 of the Internal Revenue Code or any successor
          provision thereto, (ii) loss of Executive's property due to
          casualty, or (iii) other similar extraordinary and unforeseeable
          circumstances arising as a result of events beyond the control of
          Executive.  The circumstances that will constitute an
          unforeseeable emergency will depend upon the facts of each case,
          but, in any case, a payment (or release) of all or any portion of
          the Deferred Compensation in the event of an unforeseeable
          emergency may not be made to the extent that such hardship is or
          may be relieved;

                        (i)    Through reimbursement or compensation by
                 insurance or otherwise,

                        (ii)   By liquidation of Executive's assets, to the
                 extent the liquidation of such assets would not itself
                 cause severe financial hardship, or

                        (iii)  By cessation of the deferral of the payment
                 of the Deferred Compensation pursuant to paragraph 2,
                 above.

                 4.     The Company's obligation to pay the Deferred
          Compensation or release of common stock representing Stock
          Credits constitutes a mere promise by the Company to make these
          payments at the times specified herein.  Accordingly, Executive
          shall have the status of a general unsecured creditor with
          respect to the Deferred Compensation.  Executive's rights to the
          payment of Deferred Compensation or the release of common stock
          representing Stock Credits shall not be subject in any manner to
          anticipation, alienation, sale, transfer, assignment, pledge,
          encumbrance, attachment, or garnishment by creditors of Executive
          or his estate or any beneficiary of either Executive or his
          estate.






                                 EMPLOYMENT AGREEMENT
                                 --------------------

               AGREEMENT, dated this 1st day of August, 1997, by and
          between INTERNATIONAL MUREX TECHNOLOGIES CORPORATION,
          incorporated under the laws of the Province of British Columbia
          (the "Company"), and C. ROBERT CUSICK ("Executive").

               WHEREAS, the Company and Executive previously entered into
          an Employment Agreement dated January 1, 1995; and

               WHEREAS, the term of the employment relationship created by
          such Employment Agreement has not expired; and

               WHEREAS, the Company and Executive desire to amend and
          restate the terms and conditions of their employment relationship
          as it relates to the period subsequent to 1 August, 1997.

               NOW THEREFORE, in consideration of the foregoing and the
          mutual agreements contained herein, the Company and Executive
          agree as follows:

               1.   Employment.  The Company hereby employs Executive, and
                    ----------
          Executive accepts such employment and agrees to perform services
          for the Company, for the period and upon the other terms and
          conditions set forth in this Agreement.

               2.   Term.  The initial term of Executive's employment
                    ----
          hereunder shall be for a period of three (3) years, commencing as
          of 1 August 1997 (the "Commencement Date"), subject to earlier
          termination as hereinafter specified in Section 8.  At each
          anniversary date of the Commencement Date (each a "Renewal
          Date"), the then remaining term of this Agreement shall be
          extended for an additional one-year period unless either party
          hereto shall have provided written notice to the other party of
          such non-renewal of this Agreement on or within three (3) months
          before such Renewal Date.  In the event that either party shall
          provide the other party with written notice of non-renewal of
          this Agreement, this Agreement shall not be extended as of any
          subsequent Renewal Date but shall remain effective in accordance
          with its terms (subject to termination in accordance with Section
          8 hereof) until the end of the then current term of this
          Agreement.  A non-renewal of this Agreement in accordance with
          this Section 2 shall not constitute a termination of this
          Agreement for the purpose of Sections 5 or 8 hereof.

               3.   Position and Duties.
                    -------------------
                    3.01.  Service with the Company.  During the Term of
                           ------------------------
          this Agreement, Executive shall serve as, and his title shall be,
          Vice Chairman of the Company or such other position as Executive
          and the Board of Directors shall from time to time agree.  In
          such position, Executive agrees to perform such executive
          employment duties consistent with such position as the Board of
          Directors of the Company shall assign to him from time to time. 
          Executive also agrees to serve, during the Term hereof, as
          requested by the Board, and without any additional compensation,
          as a Director of the Company and as an executive officer and/or
          director of any corporations affiliated with the Company.  The
          compensation payable to Executive herein shall be paid by the
          Company or by a subsidiary of the Company as designated by
          Executive.

                    3.02.  Performance of Duties.  Executive agrees to
                           ---------------------
          serve the Company faithfully and to the best of his ability and
          to devote the time, attention and efforts necessary to advance
          the business and affairs of the Company during the Term of this
          Agreement.  It is understood and agreed that Executive may pursue
          personal investments requiring time commitments that do not
          conflict with his obligations to the Company, including those in
          the preceding sentence.  Executive hereby confirms that he is
          under no contractual commitments inconsistent with his
          obligations set forth in this Agreement, and that during the Term
          of this Agreement, he shall not render or perform services, or
          enter into any contract to do so, for any other corporation,
          firm, entity or person which are inconsistent with the provisions
          of this Agreement.

               4.   Compensation.
                    ------------

                    4.01.  Base Salary.  As compensation for all services
                           -----------
          to be rendered by Executive under this Agreement, the Company
          shall pay to Executive an initial base annual salary (the "Base
          Salary") of U.S. $265,000, which salary shall be paid in
          semi-monthly installments in accordance with the Company's normal
          payroll procedures and policies.  The base salary shall be
          increased on January 1, 1998 and on each January 1 thereafter by
          the percentage equal to the percentage increase in the Consumer
          Price Index maintained by the United States Bureau of Labor
          Statistics for the Atlanta, Georgia metropolitan area or an
          equivalent index (the "Index") as of January 1 of such year over
          the Index for the immediately preceding January 1.  Should the
          Index be modified or discontinued, appropriate adjustment shall
          be made to reflect such modification or to refer to a similar
          index.  Additionally, Executive's Base Salary shall be reviewed
          annually and may be increased by an amount to be determined by
          the Compensation/Option Committee (the "Committee") on the basis
          of Executive's performance.

                    4.02.  Incentive Compensation.  In addition to the Base
                           ----------------------
          Salary described in Section 4.01, Executive shall be eligible to
          receive incentive compensation pursuant to the Senior Management
          Incentive Plan as approved by the Committee or such other plans
          as may from time to time be available.

                    4.03.  Deferral of Compensation.  Executive shall be
                           ------------------------
          entitled to elect to defer the receipt of up to seventy five
          percent (75%) of his Base Salary and Incentive Compensation for
          each calendar year during which this Agreement is in effect. 
          Executive shall make the election to defer his compensation for a
          calendar year by giving written notice to the Company of his
          desire to do so in writing no later than December 31 of the
          immediately preceding calendar year.  In the event that Executive
          elects to defer the payment of any compensation due hereunder in
          the manner contemplated by this Section 4.03, the terms and
          conditions set forth in Exhibit A hereto with respect to the
                                  ---------
          circumstances under which Executive shall be entitled to the
          payment of the deferred compensation as well as the interest
          earned thereon and the timing and method of those payments shall
          be applicable.  Also, in such event, each of the periodic
          payments of Executive's Base Salary for any year in which
          Executive has elected to defer receipt of a portion of his Base
          Salary shall be reduced by the percentage amount of his total
          Base Salary which he has elected to defer.

                    4.04.  Participation in Benefit Plans.  Executive shall
                           ------------------------------
          also be entitled, to the extent that his position, title, tenure,
          salary, age, health and other qualifications make him eligible,
          to participate in all employee benefit plans or programs
          (including medical/dental and life insurance, retirement pension,
          stock option incentives, vacation time, sick leave and holidays)
          of the Company currently in existence on the date hereof or as
          may hereafter be instituted from time to time.  Executive's
          participation in any such plan or program shall be subject to the
          provisions, rules and regulations applicable thereto.

                    4.05.  Expenses.  In accordance with the Company's
                           --------
          policies established from time to time, the Company shall pay or
          reimburse Executive for all reasonable and necessary
          out-of-pocket expenses incurred by him in the performance of his
          duties under this Agreement, subject to the timely presentment of
          appropriate vouchers and receipts.

                    4.06.  Car Allowance.  The Company shall provide
                           -------------
          Executive with a car or pay a car allowance in amount recommended
          by the Executive Committee and approved by the Committee.

                    4.07.  Vacation.  Executive will be also be entitled to
                           --------
          the highest number of vacation days with full pay during each
          twelve months in which this Agreement is in effect as are
          available to any other key employees of the Company or its
          subsidiaries, without any reduction based upon length of service
          to the Company.

                    4.08.  Club and Professional Dues.  During the term of
                           --------------------------
          this Agreement, Executive will be entitled to the
          club/professional society membership dues and monthly charges and
          an annual physical examination by the physician of Executive's
          choice.  Amounts paid for club/professional society membership
          dues and monthly charges shall not exceed US $5,000 annually.  In
          the event that Executive is required to pay any tax on such
          reimbursement, the amount to be reimbursed to Executive shall be
          grossed up by such amount as shall ensure that Executive receives
          the same amount as he would have received had not such tax been
          payable.                                                          
                    4.09.  Double Tax Liability.  In the event that in any
                           --------------------
          year during the term of this Agreement Executive is required to
          pay income taxes on any portion of his income for that year both
          to the United States and to the United Kingdom, the Company shall
          pay to Executive the amount which, after taking into account the
          taxes required to be paid by Executive as a result of Executive's
          receipt of such payment from the Company, shall cause Executive's
          after-tax return on his income to equal the amount which would
          have been available to Executive had no United Kingdom taxes been
          due with respect to such income.  The amounts due from the
          Company pursuant to the immediately preceding sentence shall be
          determined by Executive's tax return preparer, shall take into
          account any foreign tax credits or other credits and deductions
          allowed against his United States tax liability, and shall be
          paid to Executive no later than fifteen (15) days following the
          date on which Executive files the first tax return in which the
          income subject to taxation in both the United States and the
          United Kingdom is reported in any year, or within fifteen days
          following the date on which the relevant taxing authority
          determines that Executive's income is subject to taxation both in
          the United States and in the United Kingdom, as the case may be.

                    4.10.  Tax  and Estate Planning.  The Company agrees to
                           ------------------------
          reimburse Executive for the cost of financial, tax and estate
          planning for each 365-day period in which this Agreement is in
          effect in amount not to exceed US $3,000 for each 365-day period. 
          In the event that Executive is required to pay any tax on such
          reimbursement, the amount to be reimbursed to Executive shall be
          grossed up by such amount as shall ensure that Executive receives
          the same amount as he would have received had not such tax been
          payable.

                    4.11.  Additional Benefits.  During the term of this
                           -------------------
          Agreement, Executive shall be entitled to participate in all
          present and future employee benefit plans and all other
          compensation and benefit plans, programs and structures as may
          from time to time be made available by the Company to all other
          key corporate executives of the Company, and on terms and
          conditions no less favorable than those generally available to
          other such employees.  In the event that the Company elects to
          obtain key man life insurance insuring Executive, Executive shall
          make himself available for the necessary physical examinations
          and shall cooperate in all other respects with the Company's
          efforts to obtain such insurance.

               5.   Compensation upon Termination.
                    -----------------------------   
                    (a)  In the event this Agreement is terminated pursuant
          to Subsection 8.01(a) hereof, in addition to any benefits to
          which Executive may then or following the termination of his
          employment be entitled under any other applicable policy or plan
          of the Company then in effect (including basic life insurance
          which coverage equals two times annual salary, and survivor
          benefits which provide Accidental Death & Dismemberment for each
          employee at two times the annual salary), the Company shall pay
          to Executive's estate his Base Salary, incentive compensation and
          benefits due through the effective date of termination.  In the
          event that such termination occurs on any date other than the
          last day of the fiscal year, the incentive compensation shall be
          based upon the performance goals achieved at the end of the
          fiscal year, but shall be prorated based upon the number of days
          which have elapsed in the fiscal year through the date of
          termination.  Payment of this incentive compensation, or the
          release of any stock representing incentive compensation, due
          under this Section 5(a) shall be made no later than 120 days
          following the end of the fiscal year with respect to which it is
          being paid.  Payment of all other amounts under this Section 5(a)
          shall be made not later than the 30th day following the effective
          date of termination.  Executive's estate shall be entitled to
          receive an amount equal to twenty-four (24) times his then
          current monthly Base Salary.

                    (b)  In the event this Agreement is terminated pursuant
          to Subsection 8.01(b)(i) hereof, Executive or his representative
          shall be entitled to receive an amount equal to twenty-four (24)
          times his then current monthly Base Salary, less any disability
          insurance benefits payable to Executive during such twenty-four
          month period from disability policies provided by the Company.

                    (c)  In the event this Agreement is terminated pursuant
          to Subsection 8.01(b)(ii) or (iii) hereof, Executive shall not be
          entitled to any compensation other than his then current Base
          Salary which has accrued through his date of termination, subject
          to the Company's right of offset based upon acts of Executive
          which gave rise to the termination.

                    (d)  In the event that Executive is terminated pursuant
          to Subsection 8.01(c) hereof, Executive shall be entitled to a
          severance allowance equal to the greater of (i) his Base Salary
          for all months remaining in his then current term, or (ii) his
          then current monthly Base Salary for twenty-four (24) months.

                    (e)  Subject to Section 5(a), payments or the release
          of stock representing incentive compensation to Executive
          pursuant to this Section 5 shall be made in either a lump-sum
          payment or, at the sole discretion of the Company, in four (4)
          equal payments within six (6) months of termination of the
          Agreement.

                    (f)  In the event that Executive is terminated pursuant
          to Subsections 8.01(a), 8.01(b)(i) or 8.01(c) hereof, the
          expiration dates of Executive's options currently outstanding
          pursuant to any of the Company's stock option plans will extended
          twenty-four (24) months from the date of such termination.

               6.   Confidential Information.  Except as permitted or
                    ------------------------
          directed by the Company's Board of Directors, Executive shall not
          during the Term of this Agreement or at any time thereafter
          divulge, furnish or make accessible to anyone for use in any way
          (other than in the ordinary course of the business of the
          Company) any confidential or secret knowledge or information of
          the Company (for the purposes of Sections 6 through 8 hereof, the
          term "Company" shall be deemed to include any subsidiary or
          affiliate of the Company) which Executive has acquired or become
          acquainted with or will acquire or become acquainted with prior
          to the termination of the period of his employment by the
          Company, whether developed by himself or by others, concerning
          any trade secrets, confidential or secret designs, processes,
          formulae, plans, devices or material (whether or not patented or
          patentable) directly or indirectly useful in any aspect of the
          business of the Company, and confidential customer or supplier
          lists of the Company, any confidential or secret development or
          research work of the Company, or any other confidential or secret
          aspects of the business of the Company.  Executive acknowledges
          that the above-described knowledge or information constitutes a
          unique and valuable asset of the Company acquired at great time
          and expense by the Company and its predecessors, and that any
          disclosure or other use of such knowledge or information other
          than for the sole benefit of the Company would be wrongful and
          would cause irreparable harm to the Company.  Both during and
          after the Term of this Agreement, Executive shall refrain from
          any acts or omissions that would reduce the value of the use of
          such knowledge or information to the Company.  The foregoing
          obligations of confidentiality, however, shall not apply to any
          knowledge or information which is now published or which
          subsequently becomes generally publicly known, other than as a
          direct or indirect result of the breach of this Agreement by
          Executive. 

               7.   Non-Competition, Solicitation of Customers,
                    -------------------------------------------
                    Solicitation of Employees.
                    -------------------------

                    7.01.  Non-Competition.
                           ---------------
                    (a)  Executive agrees that, during the period of his
          employment hereunder and for a period of one (1) year following
          the termination of such employment, he shall not directly engage
          in competition with the Company within the "Territory" (as
          hereinafter defined) in any management capacity in any phase of
          the Company's business of developing, manufacturing,
          distributing, marketing, leasing or selling any of the products
          which the Company is in the business of developing,
          manufacturing, distributing, marketing, leasing to others or
          selling (the "Competitive Areas") during the Term of this
          Agreement or which the Company has definitive plans to develop,
          manufacture or market.

                    (b)  The "Territory" shall be that area throughout the
          world in which the Company presently markets its products.  This
          Agreement shall be deemed automatically amended without the need
          of further action by any party to add to any new countries or
          parts thereof where after the date hereof and prior to the
          termination of Executive's employment the Company begins to
          market its products and to delete any countries after no Company
          products have been sold there for a period of six months.

                    (c)  The restrictions in this Section 7 shall not apply
          with respect to (i) a passive investment by Executive of less
          than 5% of the outstanding shares of capital stock of any
          corporation, or (ii) employment by Executive with an entity in a
          management capacity in an area of business which is not, directly
          or indirectly, a Competitive Area.

                    7.02.  Agreement Not to Solicit Customers.  Executive
                           ----------------------------------
          agrees that during his employment by the Company hereunder and
          for the two (2) year period following the termination of such
          employment, he shall not, without the prior written consent of
          the Company, within the Territory, either directly or indirectly,
          on his own behalf or in the service or on behalf of others,
          solicit, divert or appropriate, or attempt to solicit, divert or
          appropriate, to any competing business any person or entity whose
          account with the Company was sold or serviced by or under the
          supervision of Executive during the year preceding the
          termination of such employment.

                    7.03.  Agreement Not to Solicit Employees.  Executive
                           ----------------------------------
          agrees that during his employment by the Company hereunder and
          for the two (2) year period following the termination of such
          employment, he shall not, either directly or indirectly, on his
          own behalf or in the service or on behalf of others, solicit,
          divert, or attempt to solicit or divert any person then employed
          by the Company.

               8.   Termination.
                    -----------

                    8.01.  Grounds for Termination.  This Agreement shall
                           -----------------------
          terminate prior to the expiration of the initial Term set forth
          in Section 2 or any extension thereof in the event that at any
          time during such initial Term or any extension thereof:

                    (a)  Executive shall die; or

                    (b)  The Board of Directors of the Company shall
                         determine that:

                       (i)   Executive has become disabled; or

                      (ii)   Executive has breached this Agreement in any
                    material respect, which breach is not cured by
                    Executive or is not capable of being cured (as
                    determined in the sole discretion of the Company's
                    Board of Directors) by Executive within thirty (30)
                    days after written notice of such breach is delivered
                    to Executive; or
                     (iii)   In its sole discretion, Cause exists.  "Cause"
                    means (A) conduct amounting to fraud, embezzlement or
                    misappropriation as against the Company, (B) the
                    willful and knowing material breach of any fiduciary
                    duty owed to the Company as an officer of the Company
                    other than done at the direction of the Board of
                    Directors, (C) having been convicted of a criminal
                    offense which may have a material adverse effect on the
                    Company or the ability of Executive to carry out his
                    duties of employment, or (D) the knowing failure of
                    Executive to follow specific directives of the Board of
                    Directors of the Company consistent with his duties. 
                    If the Board of Directors terminates this Agreement
                    pursuant to this Section 8.01(b)(iii),  Executive will
                    be provided ninety (90) days written notice.

                         (c)  The Board of Directors of the Company shall
               determine, in its sole discretion, that the termination of
               this Agreement is in the best interest of the Company, and
               in which event Executive shall have no duty to mitigate his
               damages.  If the Board of Directors terminates this
               Agreement pursuant to this Section 8.01(c), Executive will
               be provided ninety (90) days written notice.

          Notwithstanding any termination of this Agreement, Executive, in
          consideration of his employment hereunder to the date of such
          termination, shall remain bound by the provisions of this
          Agreement which specifically relate to periods, activities or
          obligations upon or subsequent to the termination of Executive's
          employment.

                    8.02.  "Disability" Defined.  The Board of Directors
                           --------------------
          may determine that Executive has become disabled, for the purpose
          of this Agreement, in the event that Executive shall fail,
          because of illness or other physical or mental incapacity, to
          render services of the character contemplated by this Agreement
          for an aggregate of more than twelve (12) weeks during any twelve
          (12) month period.

                    8.03.  Surrender of Records and Property.  Upon
                           ---------------------------------
          termination of his employment with the Company, Executive shall
          deliver promptly to the Company all records, manuals, books,
          blank forms, documents, letters, memoranda, notes, notebooks,
          reports, data, tables, calculations or copies thereof, which are
          the property of the Company and which relate in any way to the
          business, products, practices or techniques of the Company, and
          all other property, trade secrets and confidential information of
          the Company, including, but not limited to, all documents which
          in whole or in part contain any trade secrets or confidential
          information of the Company, which in any of these cases are in
          his possession or under this control.

               9.   Assignment and Inurement.  This Agreement shall enure
                    ------------------------
          to the benefit of and be binding upon the parties hereto and
          their respective heirs, successors, administrators, successors
          and permitted assigns.  The Company may, without the consent of
          Executive, assign its rights and obligations under this Agreement
          to any corporation, firm or other business entity with or into
          which the Company may merge or consolidate, or to which the
          Company may sell or transfer all or substantially all of its
          assets or of which 50% or more of the equity investment and of
          the voting control is owned, directly or indirectly, by, or is
          under common ownership with, the Company; provided, however, that
          if the assignee was not previously part of a consolidated group
          with the Company, Executive will receive payments and benefits as
          outlined in Exhibit B, attached hereto and incorporated herein.

               10.  Injunctive Relief.  Executive agrees that it would be
                    -----------------
          difficult to compensate the Company fully for damages for any
          violation of the provisions of this Agreement, including without
          limitation the provisions of Sections 6, 7 and 8.03. 
          Accordingly, Executive specifically agrees that the Company shall
          be entitled to temporary and permanent injunctive relief to
          enforce the provisions of this Agreement.  This provision with
          respect to injunctive relief shall not, however, diminish the
          right of the Company to claim and recover damages in addition to
          injunctive relief.

               11.  Miscellaneous.
                    -------------

                    11.01.  Governing Law.  This Agreement is made under
                            -------------
          and shall be governed by and construed in accordance with the
          laws of the Commonwealth of Pennsylvania, United States, subject
          to any principles of conflict of laws.

                    11.02.  Prior Agreements.  This Agreement contains the
                            ----------------
          entire agreement of the parties relating to the subject matter
          hereof and supersedes all prior agreements and understandings
          with respect to such subject matter, and the parties hereto have
          made no agreements, representations or warranties relating to the
          subject matter of this Agreement which are not set forth herein.

                    11.03.  Withholding Taxes.  The Company may withhold
                            -----------------
          from any benefits payable under this Agreement all federal,
          state, city and other taxes as shall be required pursuant to any
          law or governmental regulation or ruling.

                    11.04.  Amendments.  No amendment or modification of
                            ----------
          this Agreement shall be deemed effective unless made in writing
          signed by the party against whom enforcement of the waiver or
          estoppel is sought.  Any written waiver shall not be deemed a
          continuing waiver unless specifically stated, shall operate only
          as to the specific term or condition for the future or as to any
          act other than that specifically waived.

                    11.05.  Notices.  Any notice, request, demand or other
                            -------
          document to be given hereunder shall be in writing, and shall be
          delivered personally or sent by registered, certified or express
          mail or facsimile followed by mail as follows:

                         If to the Company:

                              Board of Directors
                              650 Woodlawn Road West
                              Guelph, Ontario
                              N1K 1B8
                              CANADA

                         If to Executive:

                              C. Robert Cusick
                              1100 Lancaster Avenue
                              Pittsburgh, Pennsylvania  15218

          or to such other address as either party hereto may hereinafter
          duly give to the other.

                    11.06.  Severability.  To the extent any provision of
                            ------------
          this Agreement shall be invalid or unenforceable, it shall be
          considered deleted herefrom and the remainder of such provision
          and of this Agreement shall be unaffected and shall continue in
          full force and effect.  In furtherance and not in limitation of
          the foregoing, should the duration or geographical extent of, or
          business activities covered by any provision of this Agreement be
          in excess of that which is valid or enforceable under applicable
          law, then such provision shall be construed to cover only that
          duration, extent or activities which may validly and enforceably
          be covered.  Executive acknowledges the uncertainty of the law in
          this respect and expressly stipulates that this Agreement be
          given the construction which renders its provisions valid and
          enforceable to the maximum extent (not exceeding its express
          terms) possible under applicable law.

               IN WITNESS WHEREOF, the parties have executed this Agreement
          as of the day and year set forth above.


          -----------------------------------
               C. Robert Cusick



          INTERNATIONAL MUREX TECHNOLOGIES
          CORPORATION



          By:
             --------------------------------
               Victor A. Rice, on behalf of the Compensation
               Committee and the Board of Directors


                                     EXHIBIT "A"

                              DEFERRED COMPENSATION PLAN
                              --------------------------

               1.   At the time the Executive elects to defer compensation
          pursuant to Section 4.03 of the Employment Agreement, the
          Executive shall also elect the percentage of such compensation to
          be credited from the date of deferral to the date it is paid to
          the Executive with either (a) simple interest at a rate per annum
          equal to the average of the rates then being earned by the
          Company on deposits with a term of ninety days or less, adjusted
          on the first day of each calendar quarter or (b) the same rate of
          return experienced by the common stock of the Company.  The 
          portion of the compensation deferred by the Executive to which
          the Executive elects to have the Company common stock rate of
          return apply shall be hypothetically invested in shares of the
          Company's common stock based on the closing price of the
          Company's common stock on the Nasdaq National Market System, or
          such other exchange that the Company's common stock may be listed
          at the time, on the business day prior to the date on which the
          compensation would otherwise be paid.  The number of shares of
          the Company's common stock in which the Executive has
          hypothetically invested shall be adjusted to reflect stock
          splits, stock dividends and other capital changes affecting the
          outstanding common stock of the Company in the same manner as an
          equivalent number of actual shares of the Company's common stock
          are adjusted.  In addition, all cash distributions and the fair
          market value (as determined in good faith by the Company) of any
          property distributions with respect to shares of common stock of
          the Company shall be reinvested in the common stock of the
          Company based on the closing price of the common stock as
          reported on the Nasdaq National Market System, or such other
          exchange that the Company's common stock may be listed at the
          time, on the business day prior to the distribution.  The portion
          of the Executive's compensation deferred hereunder and credited
          with simple interest, together with such simple interest, shall
          be referred to herein as "Deferred Compensation".  The portion of
          Executive's compensation deferred hereunder and credited with the
          rate of return of the common stock of the Company shall be
          reflected in hypothetical shares of the Company's common stock
          with each such share being referred to herein as a "Stock
          Credit".  On December 31st of each year during which any Deferred
          Compensation or Stock Credits remain unpaid, the Company shall
          provide the Executive with a statement setting forth the amount
          of his unpaid Deferred Compensation and the number of outstanding
          Stock Credits.

               2.   The Deferred Compensation shall be paid to Executive in
          a lump sum following the termination of his employment with the
          Company for any reason on the 30th day following the date of
          termination.  The number of Stock Credits credited to the
          Executive shall be paid to the Executive on the 30th date
          following the date of his termination, by the release of common
          stock to the Executive."

               3.   Notwithstanding the foregoing, in the event of the
          occurrence of an "unforeseeable emergency," as hereinafter
          defined, Executive shall be entitled to a payment from the
          Deferred Compensation (or release of common stock representing
          Stock Credits) prior to the date set forth in paragraph 2 of this
          Exhibit A of that amount reasonably required to satisfy the
          emergency need.  As used herein, "unforeseeable emergency" shall
          be limited to (i) severe financial hardship to Executive
          resulting from a sudden and unexpected illness or accident of
          Executive or of a dependent of Executive, as dependent is defined
          in Section 152 of the Internal Revenue Code or any successor
          provision thereto, (ii) loss of Executive's property due to
          casualty, or (iii) other similar extraordinary and unforeseeable
          circumstances arising as a result of events beyond the control of
          Executive.  The circumstances that will constitute an
          unforeseeable emergency will depend upon the facts of each case,
          but, in any case, a payment (or release) of all or any portion of
          the Deferred Compensation in the event of an unforeseeable
          emergency may not be made to the extent that such hardship is or
          may be relieved;

                    (i)  Through reimbursement or compensation by insurance
               or otherwise,

                    (ii) By liquidation of Executive's assets, to the
               extent the liquidation of such assets would not itself cause
               severe financial hardship, or

                    (iii)     By cessation of the deferral of the payment
               of the Deferred Compensation pursuant to paragraph 2, above.

               4.   The Company's obligation to pay the Deferred
          Compensation or release of common stock representing Stock
          Credits constitutes a mere promise by the Company to make these
          payments at the times specified herein.  Accordingly, Executive
          shall have the status of a general unsecured creditor with
          respect to the Deferred Compensation.  Executive's rights to the
          payment of Deferred Compensation or the release of common stock
          representing Stock Credits shall not be subject in any manner to
          anticipation, alienation, sale, transfer, assignment, pledge,
          encumbrance, attachment, or garnishment by creditors of Executive
          or his estate or any beneficiary of either Executive or his
          estate.


                                     EXHIBIT "B"

                             CHANGE IN CONTROL PROVISIONS

               This Exhibit "B" (the "Provisions") set forth the severance
          benefits which the Company agrees will be provided Executive in
          the event employment with the Company is terminated subsequent to
          a Change in Control of the Company under the circumstances
          described below.  In order to secure the payment of all
          obligations under these Provisions, the Company shall establish
          an irrevocable grantor trust and make contributions thereto
          sufficient to satisfy its obligations under these Provisions
          immediately upon an event which constitutes a Change in Control
          (as hereinafter defined). 

               1.   Term of these Provisions.  These Provisions shall
                    ------------------------
          commence on the date set forth in the Employment Agreement and
          shall continue in effect as long as the Employment Agreement is
          in effect, or until the Company or Executive shall have given
          notice that these Provisions shall not be extended; and provided,
          further, that, notwithstanding the delivery of any such notice,
          these Provisions shall continue in effect for a period of twenty-
          four (24) months after a Change in Control of the Company if such
          Change in Control shall have occurred while these Provisions are
          in effect.  Notwithstanding anything in this Section 1 to the
          contrary, these Provisions shall terminate if Executive or the
          Company terminates Executive's employment in accordance with the
          terms and conditions of the applicable Employment Agreement prior
          to a Change in Control of the Company.

               2.   Change in Control.  For purposes of these Provisions, a
                    -----------------
          "Change in Control" means and shall be deemed to occur if any of
          the following occurs:

               (a)  an acquisition, after September 1, 1995, by an
          individual, entity or group (within the meaning of Section
          13(d)(3) or 14(d)(2) of the Securities Exchange Act of 1934, as
          amended (the "Exchange Act")) of beneficial ownership (within the
          meaning of Rule 13d-3 promulgated under the Exchange Act) of 20%
          or more of either (i) the outstanding shares of common stock, no
          par value, of the Company (the "Common Shares"), or (ii) the
          combined voting power of the voting securities of the Company
          entitled to vote generally in the election of directors (the
          "Voting Securities"); or 

               (b)  individuals who, as of September 1, 1995, constituted
          the Board (the "Incumbent Board"), cease for any reason to
          constitute at least a majority of the Board, provided, however,
          that any individual becoming a director subsequent to September
          1, 1995, whose election, or nomination for election by the
          Company's shareholders, was approved by a vote of at least a
          majority of the directors then serving and comprising the
          Incumbent Board shall be considered as though such individual
          were a member of the Incumbent Board, but excluding, for this
          purpose, any such individual whose initial assumption of office
          occurs as a result of either an actual or threatened election
          contest (as such terms are used in Rule 14a-11 of Regulation 14A
          promulgated under the Exchange Act ) or other actual or
          threatened solicitation of proxies or consents; or 

               (c)  approval by the shareholders of the Company of (i) a
          tender offer to acquire 20% or more of the Common Shares or
          Voting Securities, (ii) a reorganization, (iii) a merger, or (iv)
          a consolidation, other than a reorganization, merger or
          consolidation with respect to which all or substantially all of
          the individuals and entities who were the beneficial owners,
          immediately prior to such reorganization, merger or
          consolidation, of the Common Shares and Voting Securities
          beneficially own, directly or indirectly, immediately after such
          reorganization, merger or consolidation, more than 80% of the
          then outstanding Common Shares and Voting Securities (entitled to
          vote generally in the election of directors) of the corporation
          resulting from such reorganization, merger or consolidation in
          substantially the same proportions as their respective ownership,
          immediately prior to such reorganization, merger or
          consolidation, of the Common Shares or Voting Securities; or

               (d)  approval by the Company's shareholders of (i) a
          complete or substantial liquidation or dissolution of the
          Company; or (ii) the sale or other disposition of all or
          substantially all of the assets of the Company.

               3.   Termination Following a Change in Control.  If any of
                    -----------------------------------------
          the events described in Section 2 hereof constituting a Change in
          Control of the Company shall have occurred, Executive shall be
          entitled to the benefits provided in Section 4(c) hereof upon the
          termination of employment with the Company after such Change in
          Control, unless such termination is because of death, by the
          Company for Cause or Disability (as each such term is defined in
          the Employment Agreement), or by Executive other than for Good
          Reason (as hereinafter defined).

               (a)  Good Reason.  Termination by Executive of employment
                    -----------
          for "Good Reason" for the purpose of these Provisions shall mean
          termination based on:

                     (i)  a determination by Executive, in his reasonable
          judgment, that there has been a material adverse change in his
          status or position(s) with the Company from those in effect
          immediately prior to the Change in Control, including, without
          limitation, a material adverse change in Executive's status or
          position as a result of a diminution of his duties or
          responsibilities (other than, if applicable, any such change
          directly attributable to the fact that the Company is no longer
          publicly owned) or the assignment to him of any duties or
          responsibilities which are inconsistent with such status or
          position(s), or any removal of Executive from, or any failure to
          reappoint or reelect him to, such position(s) (except in
          connection with the termination of employment for Cause or
          Disability or as a result of death or by Executive other than for
          Good Reason);

                    (ii) a reduction by the Company in base salary from
          that in effect immediately prior to the Change in Control;

                    (iii)     the failure by the Company to continue in
          effect any Plan (as herein defined) in which Executive
          participates in at the time of the Change in Control of the
          Company (or plans providing him with substantially similar
          benefits), or the taking of any action, or the failure to act, by
          the Company which would adversely affect continued participation
          in any of such Plans on at least as favorable a basis as is the
          case on the date of the Change in Control or which would
          materially reduce Executive's benefits in the future under any of
          such plans or deprive him of any material benefit enjoyed at the
          time of the Change in Control.  For purposes of these Provisions,
          "Plan" shall mean any compensation plan or any employee benefit
          plan such as a thrift, pension, profit sharing, medical,
          disability, accident, life insurance plan or a relocation plan or
          policy or any other plan, program or policy of the Company
          intended to benefit employees;

                    (iv) the failure by the Company to provide and credit
          the number of paid vacation days to which Executive is then
          entitled in accordance with the Company's normal vacation policy
          in effect immediately prior to the Change in Control;

                    (v)  the Company's requiring Executive to be based at
          any office that is greater than fifty  (50) miles from where his
          office is located immediately prior to the Change in Control
          except for required travel on the Company's business to an extent
          substantially consistent with the business travel obligations
          which he undertook on behalf of the Company prior to the Change
          in Control;

                    (vi) the failure by the Company to obtain from any
          Successor (as hereinafter defined) the assent to these Provisions
          contemplated by Section 5(a) hereof;

                    (vii)     any termination by the Company of Executive's
          employment which is not effected pursuant to a Notice of
          Termination satisfying the requirements of paragraph (c) below;
          and for purposes of these Provisions, no such termination shall
          be effective; or

                    (viii)    any refusal by the Company to continue to
          allow Executive to attend to matters or engage in activities not
          directly related to the business of the Company which, prior to
          the Change in Control, he was previously permitted to attend to
          or engage in.

               (b)  Window Periods.  Notwithstanding anything in these
                    --------------
          Provisions to the contrary, any termination by Executive for any
          reason during the thirty (30) day period immediately following a
          Change in Control of the Company (the "First Window Period")
          shall be deemed a termination for Good Reason for all purposes of
          these Provisions.  In addition, any termination by him for any
          reason during the thirty (30) day period immediately following
          the first anniversary date of a Change in Control of the Company
          (the "Second Window Period") shall be deemed a termination for
          Good Reason for all purposes of these Provisions, except all
          benefits paid hereunder shall be reduced by twelve (12) months.

               (c)  Notice of Termination.  Any termination by the Company
                    ---------------------
          or any termination by Executive following a Change in Control
          shall be communicated by written notice to the other party hereto
          which indicates the specific termination provision in these
          Provisions relied upon (the "Notice of Termination").

               (d)  Date of Termination.  "Date of Termination" following a
                    -------------------
          Change in Control shall mean:  (i)  if employment is to be
          terminated for Disability, thirty (30) days after Notice of
          Termination is given (provided that Executive shall not have
          returned to the performance of his duties on a full-time basis
          pursuant to a doctor's release during such thirty (30) day
          period), (ii) if employment is to be terminated by the Company
          for any reason other than death or Disability or by Executive
          pursuant to Sections 3(a)(vi) or 5(a) hereof or for other Good
          Reason, the date specified in the Notice of Termination, or (iii)
          if employment is terminated on account of death, the day after
          death.  In the case of termination of employment by the Company
          for Cause pursuant to Paragraph 8.01(b)(iii) of the Employment
          Agreement, if Executive has not previously expressly agreed in
          writing to the termination, then within ninety (90) days after
          receipt by him of the Notice of Termination with respect thereto,
          Executive may notify the Company that a dispute exists concerning
          the Termination, in which even the Date of Termination shall be
          the date set either by mutual written agreement of the parties or
          by such court having the matter before it.  During the pendency
          of any such dispute, the Company will continue to pay Executive
          his full compensation in effect just prior to the time the Notice
          of Termination is given and until the dispute is resolved. 
          However if such court issues a final and non-appealable order
          finding that the Company had Cause to terminate Executive then he
          must return all compensation paid after the Date of Termination
          specified in the Notice of Termination previously received.

               4.   Compensation Upon Termination or During Disability;
                    ---------------------------------------------------
                    Other Agreements.
                    ----------------

               (a)  During any period following a Change in Control of the
          Company that Executive fails to perform his duties as a result of
          incapacity due to physical or mental illness, he shall continue
          to receive his Base Salary at the rate then in effect and any
          benefits or awards under any Plan shall continue to accrue during
          such period, to the extent not inconsistent with such Plans,
          until and unless his employment is terminated pursuant to and in
          accordance with paragraph 4(c) hereof.  Thereafter, his benefits
          shall be determined in accordance with the Plans then in effect.

               (b)  If employment is terminated for Cause following a
          Change in Control of the Company, the Company shall pay to
          Executive's Base Salary through the Date of Termination at the
          rate in effect just prior to the time a Notice of Termination is
          given, plus any benefits or awards (including both the cash and
          stock components) which pursuant to the terms of any Plans have
          been earned or become payable, but which have not yet been paid. 
          Thereupon the Company shall have no further obligations to
          Executive under these Provisions.

               (c)   Subject to Section 8 hereof, if, within twenty-four
          (24) months after a Change in Control of the Company has
          occurred, Executive's employment by the Company is terminated
          other than on account of death and is terminated by the Company
          other than for Cause or Disability or by Executive for Good
          Reason, including any termination by him during the First Window
          Period or the Second Window Period (subject to reduction as set
          forth in Section 3(b)), then the Company shall pay to Executive,
          no later than the fifth (5th) day following the Date of
          Termination, without regard to any contrary provisions of any
          Plan, the following, which shall be inclusive and in place of any
          other severance benefits to which he may previously have been
          entitled under his employment agreement with the Company and
          shall constitute all of the severance benefits to which he may be
          entitled under all agreements with the Company:

                    (i)  Executive's Base Salary through the Date of
          Termination at the rate in effect just prior to the time a Notice
          of Termination is given plus any benefits or awards (including
          both the cash and stock components) which pursuant to the terms
          of any Plans have been earned or become payable, but which have
          not yet been paid (including amounts which previously had been
          deferred at his request);

                    (ii) an amount in cash equal to 299% of Executive's
          average annual taxable compensation over the base period (within
          the meaning of Section 280G(d)(2) of the Internal Revenue Code of
          1986, as amended (the "Code")) ending on the effective date of
          the Change in Control; provided, however, that the maximum amount
          which Executive  may receive under this Section 4(c)(ii) shall
          not exceed the lowest amount received by any other Company
          employee whose employment agreement with the Company contains an
          agreement substantially similar to these Provisions.  For
          purposes of this Section 4(c)(ii), the term "average annual
          taxable compensation" shall mean Executive's base salary plus
          bonuses, including any amounts deducted by the Company or
          contributed by the Company with respect to Executive or for
          Executive's account pursuant to Sections 125 and 401(k) of the
          Code and excluding the value of any fringe benefits or executive
          perquisites, and any gross-up payments thereon, which are
          includeable by Executive as taxable compensation.

               (d)  If, within twenty-four (24) months after a Change in
          Control of the Company has occurred, Executive's employment by
          the Company is terminated (i) by the Company other than for Cause
          or Disability, or (ii) by Executive for Good Reasons, then the
          Company shall maintain in full force and effect, for the
          continued benefit of Executive and his dependents for a period
          terminating on the earliest of (i) two (2) years after the Date
          of Termination, or (ii) the commencement date of equivalent
          benefits from a new employer, all insured and self-insured
          employee welfare benefit Plans in which he was entitled to
          participate immediately prior to the Date of Termination,
          provided that his continued participation is possible under the
          general terms and provisions of such Plans (and any applicable
          funding media) and he continues to pay an amount equal to regular
          contributions under such Plans for such participation.  If two
          (2) years after the Date of Termination Executive has not
          previously received, nor are then receiving, equivalent benefits
          from a new employer, the Company shall offer him continuation of
          coverage under COBRA as prescribed under Section 4980B of the
          Code.  At the expiration of such continuation coverage (or, if
          COBRA continuation coverage is not applicable to the Plan, then
          upon the expiration of the two (2) year period beginning on the
          Termination Date), the Company shall arrange, at its sole cost
          and expense, to enable him to convert he and his dependents'
          coverage under such plans to individual policies and programs
          upon the same terms as employees of the Company may apply for
          such conversions.  In the event that Executive's participation in
          any such Plan is barred, the Company, at its sole cost and
          expense, shall arrange to have issued for the benefit of
          Executive and his dependents individual policies of insurance
          providing benefits substantially similar (on an after-tax basis)
          to those which he otherwise would have been entitled to receive
          under such Plans pursuant to this paragraph 4(d) or, if such
          insurance is not available at a reasonable cost to the Company,
          the Company shall otherwise provide Executive and his dependents
          with equivalent benefits (on an after-tax basis). Executive shall
          not be required to pay any premiums or other charges in an amount
          greater than that which he would have paid in order to
          participate in such Plans.

               (e)  Until Executive obtains another full-time job, the
          Company shall provide him with professional outplacement services
          of his choosing and shall reimburse him for documented incidental
          outplacement expenses directly related to his job search such as
          resume mailing, interviewing trips, and clerical support, subject
          to a maximum cost of $50,000 for such outplacement services and
          incidental expenses; provided, however, that the Company shall
          not provide him with any such outplacement services or reimburse
          him for any such costs under this paragraph 4(e) if employment is
          terminated by Executive during the Second Window Period. 
          Executive's choice of professional outplacement services shall be
          subject to the Company's reasonable prior approval.  If the
          Company has not approved or disapproved of Executive's choice
          within ten (10) business days of receiving notice of such choice,
          the Company will be deemed to have given its approval.  Any
          disapproval issued by the Company pursuant to this Section shall
          be in writing and state the basis for such disapproval. Executive
          shall not be entitled to receive cash in lieu of the professional
          outplacement services provided pursuant to this Section.

               (f)  Except as specifically provided in paragraph 4(d)
          above, the amount of any payment provided for in this Section 4
          shall not be reduced, offset or subject to recovery by the
          Company by reason of any compensation earned as the result of
          employment by another employer after the Date of Termination, or
          otherwise.

               (g)  If, by reason of Section 280G of the Code, any payment
          or benefit received or to be received  in connection with a
          Change in Control of the Company of the termination of
          Executive's employment (whether payable pursuant to the terms of
          these Provisions ("Contract Payments") or any other plan,
          arrangement or agreement with the Company, its successors, any
          person whose actions result in a Change in Control or any
          corporation affiliated, or which, as a result of the completion
          of the transactions causing a change in control will become
          affiliated, with the Company within the meaning of Section 1504
          of the Code ("Affiliate") (which payments collectively with the
          Contract Payments are called the "Total Payments")) would not be
          deductible, in whole or in part, by the Company an Affiliate or
          other person making such payment or providing such benefit, the
          Contract Payments shall be reduced until no portion of the Total
          Payments is not deductible by reason of Section 280G of the Code. 
          For purposes of this limitation

                    (i)  no portion of the Total Payments, the receipt or
          enjoyment of which Executive shall have effectively waived in
          writing prior to the date of payment of the Contract Payments,
          shall be taken into account;

                    (ii) no portion of the Total Payments shall be taken
          into account which, in the opinion of tax counsel selected by the
          Company's independent auditors and acceptable to Executive, does
          not constitute a "parachute payment" within the meaning of
          Section 280G(b)(2) of the Code (without regard to subsection
          (A)(ii) thereof);

                    (iii)     the Contract Payments shall be reduced only
          to the extent necessary so that the Total Payments, other than
          those referred to in clauses (i) and (ii), in their entirety
          constitute reasonable compensation for services actually rendered
          with the meaning of Section 280G(b)(4) of the Code, in the
          opinion of the tax counsel referred to in clause (ii); and

                    (iv) the value of any non-cash benefit or any deferred
          payment or benefit included in the Total Payments shall be
          determined by the Company's independent auditors in accordance
          with the principles of Sections 280G(d)(3) and (4) of the Code.

               5.   Successors Binding Agreement.
                    ----------------------------

               (a)  The Company will seek, by written request at least five
          (5) business days prior to the time a natural person,
          corporation, partnership or other business entity (a "Person")
          becomes a Successor (as hereinafter defined), to have such
          Person, by agreement in form and substance satisfactory to
          Executive, assent to the fulfillment of the Company's obligations
          under these Provisions.  Failure of such Person to furnish such
          assent by the later of (i) three (3) business days prior to the
          time such Person becomes a successor or (ii) two (2) business
          days after such Person receives a written request to so assent
          shall constitute Good Reason for termination by Executive of his
          employment if a Change in Control of the Company occurs or has
          occurred.  For purposes of these Provisions, "Successor" shall
          mean any person that succeeds to, or has the practical ability to
          control (either immediately or with the passage of time), the
          Company's business directly, by merger or consolidation, or
          indirectly, by purchase of the Company's Voting Securities or
          otherwise.

               (b)  These Provisions shall inure to the benefit of and be
          enforceable by Executive's  personal legal representatives,
          executors, administrators, successors, heirs, distributees,
          devisees and legatees.  If Executive should die while any amount
          would still be payable to him hereunder if he had continued to
          live, all such amounts, unless otherwise provided herein, shall
          be paid in accordance with the terms of these Provisions to
          Executive's devisee, legatee or other designee or, if no such
          designee exists, to his estate.

               (c)  For purposes of these Provisions, the "Company" shall
          include any subsidiaries of the Company and any corporation or
          other entity which is the surviving or continuing entity in
          respect of any merger, consolidation or form of business
          combination in which the Company ceases to exist; provided,
          however, for purposes of determining whether a Change in Control
          has occurred herein, the term "Company" shall refer to
          International Murex Technologies Corporation or its successor(s).

               6.   Fees and Expenses: Mitigation.
                    -----------------------------

               (a)  The Company shall reimburse Executive, on a current
          basis, for all reasonable legal fees and related expenses
          incurred in connection with the Provisions of this Agreement
          following a Change in Control of the Company, including without
          limitation, (i) all such fees and expenses, if any, incurred in
          contesting or disputing any termination of his employment or
          incurred by him in seeking advice with respect to the matters set
          forth in Section 7 hereof or (ii) his seeking to obtain or
          enforce any right or benefit provided by these Provisions, in
          each case, regardless of whether or not his claim is upheld by a
          court of competent jurisdiction; provided, however, he shall be
          required to repay any such amounts to the Company to the extent
          that a court issues a final and non-appealable order setting
          forth the determination that the position taken by him was
          frivolous or advanced in bad faith.

               (b)  Executive shall not be required to mitigate the amount
          of any payment the Company becomes obligated to make in
          connection with these Provisions, by seeking other employment or
          otherwise.

               7.   Taxes.   All payments to be made to Executive under
                    -----
          these Provisions will be subject to required withholding of
          federal, state and local income and employment taxes.

               8.   Survival.  The respective obligations of, and benefits
                    --------
          afforded to, the Company and Executive as provided in Section 4,
          5(b), 6 and 7 of these Provisions shall survive termination of
          these Provisions.

               9.   Validity: Conflict with Employment Agreement.  The
                    --------------------------------------------
          invalidity or unenforceability of any provision of these
          Provisions shall not affect the validity or enforceability of any
          other provision of these Provisions, which shall remain in full
          force and effect.  In the event that any term or provision of
          these Provisions shall conflict or be inconsistent with any term
          or provision of the Employment Agreement by and between Executive
          and the Company, the terms and conditions of these Provisions
          shall govern.



                                      AMENDMENT
                               TO EMPLOYMENT AGREEMENT


               THIS AMENDMENT is made as  of this 6TH day of November  1997
          by INTERNATIONAL  MUREX  TECHNOLOGIES CORPORATION  organized  and
          existing  under the laws of the Province of British Columbia (the
          "Company") and C. ROBERT CUSICK (the "Executive"). 

               WHEREAS, the  Company and  the Executive  previously entered
          into   an  Employment   Agreement   dated  July   1,  1995   (the
          "Agreement"); and 

               WHEREAS,   the  Company  and   the  Executive  restated  the
          Agreement as of August 1, 1997;

               WHEREAS, the Company  and the Executive desire  to amend the
          terms of the Agreement; 

               NOW  THEREFORE, in  consideration of  the foregoing  and the
          mutual agreements contained herein, the Company and the Executive
          agree to  amend Section 4(g)  of Exhibit  A of  the Agreement  by
          deleting the entire section and replacing it with the following: 

                    "(g)  If, by  reason of Section 28OG  of the Code,  any
          payment  or benefit received or to be received in connection with
          a  Change in  Control  of  the  Company  of  the  termination  of
          Executive's employment (whether payable  pursuant to the terms of
          these  Provisions  ("Contract  Payments")   or  any  other  plan,
          arrangement or  agreement with  the Company, its  successors, any
          person  whose  actions  result in  a  Change  in  Control or  any
          corporation  affiliated, or which, as a  result of the completion
          of the  transactions  causing a  change  in control  will  become
          affiliated,  with the Company within  the meaning of Section 1504
          of the  Code ("Affiliate") (which payments  collectively with the
          Contract Payments are called the "Total Payments"))  would not be
          deductible, in whole or in part,  by the Company, an Affiliate or
          other person making such payment or providing such benefit and is
          or becomes  subject to the tax imposed  under Section 4999 of the
          Code  or any  similar  tax that  may  hereafter be  imposed  (the
          "Excise  Tax"), the  Executive  may choose  to have  the Contract
          Payment reduced  in accordance  with Paragraph (A)  hereof or  to
          receive the Tax Reimbursement  Payment described in Paragraph (B)
          hereof. 

                    (A)   Executive will receive the  Total Payments unless
          (a)  the after-tax amount that would be retained by the Executive
          (after taking  into account all  federal, state and  local income
          taxes payable by the Executive and the amount of any Excise Taxes
          payable  by the  Executive  if  he  were  to  receive  the  Total
          Payments) has  a lesser  after-tax value than  (b) the  after-tax
          amount that would be retained by the Executive (after taking into
          account  all federal, state and local income taxes payable by the
          Executive)  if he were to  receive the Total  Payments reduced by
          the minimum amount necessary to result in no portion of the Total
          Payments  being  subject  to   any  Excise  Taxes  (the  "Reduced
          Payments"), in  which case  the Executive  may choose  to receive
          only to the  Reduced Payment. If the Executive is  to receive the
          Reduced  Payment, the  Executive shall  be entitled  to determine
          which  of the  Contract Payments,  and  the relative  portions of
          each, are to be reduced. For the purposes of this limitation: 

                    (i)    no portion of the Total Payments, the receipt or
          enjoyment of which the Executive shall have effectively waived in
          writing  prior to the date  of payment of  the Contract Payments,
          shall be taken into account; 

                    (ii)   no  portion of the Total Payments shall be taken
          into account which, in the opinion of tax counsel selected by the
          Company's independent  auditors and acceptable  to the Executive,
          does not constitute  a "parachute payment" within  the meaning of
          Section  280G(b)(2) of  the  Code (without  regard to  subsection
          (A)(ii) thereof); 

                    (iii)  the  Contract Payments shall be  reduced only to
          the extent necessary so that the Total Paymcnts, other than those
          referred to in clauses (i) and (ii), in their entirety constitute
          reasonable compensation  for services actually rendered  with the
          meaning of Section 280G(b)(4)  of the Code, in the opinion of the
          tax counsel referred to in clause (ii); 

                    (iv)  the value of any non-cash benefit or any deferred
          payment  or  benefit  included in  the  Total  Payments  shall be
          determined   by   the   Company's   independent   auditors   (the
          "Accountants")in   accordance  with  the  principles  of  Section
          280G(d)(3) and (4) of the Code; and 

                    (v)   in the event that the Excise Tax is  subsequently
          determined  by the Accountants to  be less than  the amount taken
          into account hereunder in calculating the Contract Payments made,
          the Company  shall repay to the  Executive, at the time  that the
          amount of such reduction in the Excise Tax is finally determined,
          the portion of  such prior  Contract Payments that  has not  been
          paid to  the Executive  and that  would  have been  paid if  such
          Excise  Tax  had  been  applied  in  initially  calculating  such
          Contract  Payments, plus interest on the amount of such repayment
          at the rate provided in Section 1274(b)(2)(B) of the Code. 

                    (B)   The Executive wi11 receive, at the time the Total
          Payments are paid by the Company, a Tax Reimbursement payment (as
          defined herein). The Tax  Reimbursement Payment is defined as  an
          amount, which when added to tbe Tota1 Payments and reduced by any
          Excise Tax  on  the Total  Payments  and Excise  Tax on  the  Tax
          Reimbursement  Payment provided  for by  this Agreement  shall be
          equa1 to  the  sum  of the  amount  of the  Total  Payments.  For
          purposes of this paragraph: 

                    (i)    no portion of the Total Payments, the receipt or
          enjoyment of which the Executive shal1 have effectively waived in
          writing  prior to the date  of payment of  the Contract Payments,
          shal1 be taken into account; 

           
                    (ii)   no portion of the Total Payments shall  be taken
          into account which, in the opinion of tax counsel selected by the
          Company's independent  auditors and acceptable to  the Executive,
          does not constitute a "parachute  payment" within the meaning  of
          Section  280G(b)(2) of  the  Code (without  regard to  subsection
          (A)(ii) thereof); and 

                    (iii)    the  value  of  any non-cash  benefit  or  any
          deferred payment or benefit included in the Total  Payments shall
          be determined by the Company's independent auditors in accordance
          with the principles of Sections 280G(d)(3) and (4) of the Code. 

                    (iv)   In the event that the Excise Tax is subsequently
          determined  by the Accountants to  be less than  the amount taken
          into account hereunder in calculating the Contract Payments made,
          the Company shall  repay to the Executive,  at the time that  the
          amount of such reduction in the Excise Tax is finally determined,
          the portion of such prior Contract Payments that has been paid to
          the  Company or to federally,  state or local  tax authorities on
          the Executive's behalf and  that would not have been paid if such
          Excise  tax  had  been  applied  in  initially  calculating  such
          Contract Payments, plus interest on the amount  of such repayment
          at  the rate  provided  in  Section  1274(b)(2)(B) of  the  Code.
          Notwithstanding the  foregoing, in the  event any portion  of the
          Contract Payment to be refunded to the Executive has been paid to
          any  federal, state  or  local tax  authority, repayment  thereof
          shall  not  be required  until actua1  refund  or credit  of such
          portion has been made to the Company; and interest payable to the
          Executive  shall not exceed interest  received or credited to the
          Company  by  such  tax authority  for  the  period  it held  such
          portion. The Executive and the Company shall  mutually agree upon
          the course of action to be  pursued (and the method of allocating
          the  expenses thereof)  if  the Company's  good  faith claim  for
          refund or credit is denied. 

                    (v)     The  portion of  the Tax  Reimbursement Payment
          attributable  to a Total Payment  shall be paid  to the Executive
          within  ten (10) business days following the payment of the Total
          Payment.  If the  amount of  such Tax  Reimbursement Payment  (or
          portion  thereof) cannot be  finally determined on  or before the
          date on which payment is due, the Company shall either pay to the
          Executive  or  withhold and  deposit  with  the Internal  Revenue
          Service on behalf of  the Executive, an amount estimated  in good
          faith  by the Accountants  to be the  minimum amount  of such Tax
          Reimbursement Payment  and shall pay  the remainder  of such  Tax
          Reimbursement  Payment  (which  Tax  Reimbursement  Payment shall
          include interest at the rate provided in Section 1274(b)(2)(B) of
          the Code) as soon as the amount thereof can be determined, but in
          no event later than forty-five  (45) calendar days after  payment
          of  the  Total  Payment. In  the  event that  the  amount  of the
          estimated   Tax   Reimbursement   Payment  exceeds   the   amount
          subsequently determined to have been  due, such excess sums shal1
          be  repaid  or refunded  pursuant  to the  provisions  of Section
          (g)(B)(iv) above." 

               Except  as specifically amended  hereby, the Agreement shall
          remain in full force and effect as prior to this Amendment. 

               IN  WITNESS  WHEREOF, the  Company  and  the Executive  have
          caused this  Amendment to be  executed on the day  and year first
          above written. 

                                        INTERNATIONAL MUREX TECHNOLOGIES,
                                        INC. 


                                        By: ____________________

                                        Title: ___________________


          ATTEST:


          By: ____________________

          Title: ____________________


                                        C. ROBERT CUSICK


                                        By:   /s/ C. Robert Cusick
                                           ----------------------------



                                      AMENDMENT
                               TO EMPLOYMENT AGREEMENT


               THIS AMENDMENT is made as  of this 6TH day of November  1997
          by INTERNATIONAL  MUREX  TECHNOLOGIES CORPORATION  organized  and
          existing  under the laws of the Province of British Columbia (the
          "Company") and STEVEN C. RAMSEY (the "Executive"). 

               WHEREAS, the  Company and  the Executive  previously entered
          into   an  Employment   Agreement   dated  July   1,  1995   (the
          "Agreement"); and 

               WHEREAS,   the  Company  and   the  Executive  restated  the
          Agreement as of August 1, 1997;

               WHEREAS, the Company  and the Executive desire  to amend the
          terms of the Agreement; 

               NOW  THEREFORE, in  consideration of  the foregoing  and the
          mutual agreements contained herein, the Company and the Executive
          agree to  amend Section 4(g)  of Exhibit  A of  the Agreement  by
          deleting the entire section and replacing it with the following: 

                   "(g)  If,  by reason  of Section 28OG  of the Code,  any
          payment  or benefit received or to be received in connection with
          a  Change in  Control  of  the  Company  of  the  termination  of
          Executive's employment (whether payable  pursuant to the terms of
          these  Provisions  ("Contract  Payments")  or  any   other  plan,
          arrangement or  agreement with  the Company, its  successors, any
          person  whose  actions  result in  a  Change  in  Control or  any
          corporation  affiliated, or which, as a  result of the completion
          of the  transactions  causing a  change  in control  will  become
          affiliated,  with the Company within  the meaning of Section 1504
          of the  Code ("Affiliate") (which payments collectively  with the
          Contract Payments are called the "Total Payments")) would not  be
          deductible, in whole or in part,  by the Company, an Affiliate or
          other person making such payment or providing such benefit and is
          or becomes  subject to the tax imposed  under Section 4999 of the
          Code or any similar tax that may hereafter be imposed ("the Excise
          Tax"),  the Executive  may  choose to  have the  Contract Payment
          reduced in accordance with Paragraph (A) hereof or to receive the
          Tax Reimbursement Payment described in Paragraph (B) hereof. 

                    (A)   Executive will receive the  Total Payments unless
          (a)  the after-tax amount that would be retained by the Executive
          (after taking  into account all  federal, state and  local income
          taxes payable by the Executive and the amount of any Excise Taxes
          payable  by the  Executive  if  he  were  to  receive  the  Total
          Payments) has  a lesser after-tax  value than  (b) the  after-tax
          amount that would be retained by the Executive (after taking into
          account  all federal, state and local income taxes payable by the
          Executive)  if he were to  receive the Total  Payments reduced by
          the minimum amount necessary to result in no portion of the Total
          Payments  being  subject  to   any  Excise  Taxes  (the  "Reduced
          Payments"),  in which  case the  Executive may choose  to receive
          only  to the Reduced Payment. If the  Executive is to receive the
          Reduced  Payment, the  Executive shall  be entitled  to determine
          which  of the  Contract  Payments, and  the relative  portions of
          each, are to be reduced. For the purposes of this limitation: 

                    (i)    no portion of the Total Payments, the receipt or
          enjoyment of which the Executive shall have effectively waived in
          writing  prior to the date  of payment of  the Contract Payments,
          shall be taken into account; 

                    (ii)    no portion of the Total Payments shall be taken
          into account which, in the opinion of tax counsel selected by the
          Company's independent  auditors and acceptable to  the Executive,
          does not constitute a "parachute payment"  within the meaning  of
          Section  280G(b)(2) of  the  Code (without  regard to  subsection
          (A)(ii) thereof); 

                    (iii)  the Contract  Payments shall be reduced only  to
          the extent necessary so that the Total Paymcnts, other than those
          referred to in clauses (i) and (ii), in their entirety constitute
          reasonable compensation  for services actually  rendered with the
          meaning of  Section 280G(b)(4) of the Code, in the opinion of the
          tax counsel referred to in clause (ii); 

                    (iv)  the value of any non-cash benefit or any deferred
          payment  or benefit  included  in  the  Total Payments  shall  be
          determined   by   the   Company's   independent   auditors   (the
          "Accountants") in accordance  with  the  principles   of  Section
          280G(d)(3) and (4) of the Code; and 

                    (v)   in the event that the Excise  Tax is subsequently
          determined  by the Accountants to  be less than  the amount taken
          into account hereunder in calculating the Contract Payments made,
          the Company shall repay  to the Executive, at  the time that  the
          amount of such reduction in the Excise Tax is finally determined,
          the portion of  such prior  Contract Payments that  has not  been
          paid to  the Executive  and  that would  have been  paid if  such
          Excise  Tax  had  been  applied  in  initially  calculating  such
          Contract Payments, plus interest on the amount of  such repayment
          at the rate provided in Section 1274(b)(2)(B) of the Code. 
           
                    (B)   The Executive wi11 receive, at the time the Total
          Payments are paid by the Company, a Tax Reimbursement payment (as
          defined herein).  The Tax Reimbursement Payment is  defined as an
          amount, which when added to tbe Tota1 Payments and reduced by any
          Excise  Tax on  the  Total Payments  and Excise  Tax  on the  Tax
          Reimbursement  Payment provided  for by  this Agreement  shall be
          equa1  to  the sum  of  the amount  of  the  Total Payments.  For
          purposes of this paragraph: 

                    (i)    no portion of the Total Payments, the receipt or
          enjoyment of which the Executive shal1 have effectively waived in
          writing  prior to the date  of payment of  the Contract Payments,
          shal1 be taken into account; 
                                
                    (ii)   no portion of the Total  Payments shall be taken
          into account which, in the opinion of tax counsel selected by the
          Company's  independent auditors and  acceptable to the Executive,
          does not constitute  a "parachute payment" within  the meaning of
          Section  280G(b)(2) of  the  Code (without  regard to  subsection
          (A)(ii) thereof); and 

                    (iii)    the  value  of any  non-cash  benefit  or  any
          deferred payment or benefit included in  the Total Payments shall
          be determined by the Company's independent auditors in accordance
          with the principles of Sections 280G(d)(3) and (4) of the Code. 

                    (iv)   In the event that the Excise Tax is subsequently
          determined  by the Accountants to  be less than  the amount taken
          into account hereunder in calculating the Contract Payments made,
          the Company  shall repay to the  Executive, at the time  that the
          amount of such reduction in the Excise Tax is finally determined,
          the portion of such prior Contract Payments that has been paid to
          the  Company or to federally,  state or local  tax authorities on
          the Executive's  behalf and that would not have been paid if such
          Excise  tax  had  been  applied  in  initially  calculating  such
          Contract Payments, plus interest on  the amount of such repayment
          at  the  rate  provided  in Section  1274(b)(2)(B)  of  the Code.
          Notwithstanding the foregoing,  in the event  any portion of  the
          Contract Payment to be refunded to the Executive has been paid to
          any  federal, state  or  local tax  authority, repayment  thereof
          shall  not  be required  until actua1  refund  or credit  of such
          portion has been made to the Company; and interest payable to the
          Executive shall not  exceed interest received or credited  to the
          Company  by  such  tax authority  for  the  period  it held  such
          portion. The Executive and the  Company shall mutually agree upon
          the course of action  to be pursued (and the method of allocating
          the  expenses  thereof) if  the  Company's good  faith  claim for
          refund or credit is denied. 

                    (v)     The  portion of  the Tax  Reimbursement Payment
          attributable  to a Total Payment  shall be paid  to the Executive
          within  ten (10) business days following the payment of the Total
          Payment.  If the  amount of  such Tax  Reimbursement  Payment (or
          portion thereof)  cannot be finally  determined on or  before the
          date on which payment is due, the Company shall either pay to the
          Executive  or  withhold and  deposit  with  the Internal  Revenue
          Service on behalf of  the Executive, an amount estimated  in good
          faith by  the Accountants to  be the  minimum amount of  such Tax
          Reimbursement Payment and  shall pay  the remainder  of such  Tax
          Reimbursement  Payment  (which  Tax Reimbursement  Payment  shall
          include interest at the rate provided in Section 1274(b)(2)(B) of
          the Code) as soon as the amount thereof can be determined, but in
          no event later  than forty-five (45) calendar  days after payment
          of  the  Total Payment.  In  the  event that  the  amount  of the
          estimated   Tax  Reimbursement   Payment   exceeds   the   amount
          subsequently determined  to have been due, such excess sums shal1
          be  repaid or  refunded  pursuant to  the  provisions of  Section
          (g)(B)(iv) above." 

               Except as specifically amended  hereby, the Agreement  shall
          remain in full force and effect as prior to this Amendment. 


               IN  WITNESS  WHEREOF, the  Company  and  the Executive  have
          caused this  Amendment to be  executed on the day  and year first
          above written. 

                                        INTERNATIONAL MUREX TECHNOLOGIES,
                                        INC. 


                                        By: ____________________

                                        Title: ___________________


          ATTEST:


          By: ____________________

          Title: ____________________


                                        STEVEN C. RAMSEY 


                                        By:   /s/ Steven C. Ramsey
                                           ---------------------------




                         FIRST AMENDMENT TO CREDIT AGREEMENT


                    This First Amendment to Credit Agreement (this
          "Amendment") effective as of the 31st day of December, 1997,
          among INTERNATIONAL MUREX TECHNOLOGIES CORPORATION, MUREX
          DIAGNOSTICS INTERNATIONAL, INC., MUREX DIAGNOSTICS CORPORATION,
          IMTC HOLDINGS (UK) LIMITED, MUREX DIAGNOSTICS, INC. and MUREX
          BIOTECH LIMITED, as Borrowers (collectively, the "Borrowers" and
          each, a "Borrower"), BANK OF AMERICA NATIONAL TRUST AND SAVINGS
          ASSOCIATION (as successor by merger to Bank of America Illinois),
          and BANK OF AMERICA NATIONAL TRUST AND SAVINGS ASSOCIATION,
          ACTING THROUGH ITS LONDON BRANCH, as Issuing Banks (collectively,
          the "Issuing Banks" and each, an "Issuing Bank"), BANK OF
          AMERICA, F.S.B., as Agent (the "Agent") and the financial
          institutions listed on the signature pages hereof as Lenders (the
          "Lenders"),

                                 W I T N E S S E T H:

                    WHEREAS, the Borrowers, the Lenders, the Issuing Bank
          and the Agent are parties to that certain Credit Agreement dated
          as of November 12, 1996 (as amended, restated, supplemented or
          otherwise modified from time to time, the "Credit Agreement");
          and

                    WHEREAS, the Borrowers have requested that certain
          terms of the Credit Agreement be amended, and the Agent, the
          Issuing Bank and the Lenders have agreed to the requested
          amendments on the terms and conditions set forth herein; and

                    NOW THEREFORE, in consideration of the foregoing
          premises and other good and valuable consideration paid by each
          party to the other, the receipt and sufficiency of which are
          hereby acknowledged, the parties hereby agree as follows:

               1.   Amendment to Article I.  Article I of the Credit
                    ----------------------
          Agreement, Definitions, is hereby amended by deleting the
                     -----------
          definitions of "BAI", "Borrower Representative", and "Borrowers"
                          ---    -----------------------        ---------
          set forth therein in their entirety and substituting the
          following, respectively, in their place:

                    ""BAI" means Bank of America National Trust and Savings
                      ---
               Association, as successor by merger to Bank of America
               Illinois.

                    "Borrower Representative" means International Murex
                     -----------------------
               Technologies Corporation, a corporation organized under the
               laws of the Province of British Columbia, or any other
               Borrower selected by the Borrowers in accordance with
               Section 2.20.
               ------------

                    "Borrowers" means International Murex Technologies
                     ---------
               Corporation, a corporation organized under the laws of the
               Province of British Columbia, Murex Diagnostics
               International, Inc., a corporation organized under the laws
               of Barbados, Murex Diagnostics Corporation, a corporation
               organized under the laws of Barbados, IMTC Holdings (UK)
               Limited, a corporation organized under the laws of England,
               Murex Diagnostics, Inc., a corporation organized under the
               laws of the State of Delaware (individually and as the
               successor by merger to IMTC Holdings, Inc.) and Murex
               Biotech Limited, a corporation organized under the laws of
               England, and "Borrower" means any of the foregoing."
                             --------

               2.   Amendment to Article VI.  Article VI of the Credit
                    -----------------------
          Agreement, Representations and Warranties, is hereby amended by
                     ------------------------------
          adding the following Section 6.27 to the end thereof:

                    "6.27  Year 2000 Compliance.  Each Borrower has
                           --------------------
               conducted a comprehensive review and assessment of its
               computer applications with respect to the "year 2000
               problem" (that is, the risk that computer applications may
               not be able to properly perform date-sensitive functions
               after December 31, 1999) and, based on that review, such
               Borrower does not believe the year 2000 problem will result
               in a material adverse change in such Borrower's business
               condition (financial or otherwise), operations, properties
               or prospects, or ability to repay the Obligations."

               3.   Amendment to Section 8.9.  Section 8.9 of the Credit
                    ------------------------
          Agreement, Contingent Obligations, is hereby deleted in its
                     ----------------------
          entirety and replaced with the following:

                    "8.9  Contingent Obligations.  IMTC shall not, and
                          ----------------------
               shall not suffer or permit any Material Subsidiary to,
               create, incur, assume or suffer to exist any Contingent
               Obligations except:

                         (a)  endorsements for collection or deposit in the
                    ordinary course of business;

                         (b)  Contingent Obligations of IMTC and its
                    Material Subsidiaries existing as of the Agreement Date
                    and listed in Schedule 8.9;
                                  ------------

                         (c)  Guaranty Obligations entered into by (i) IMTC
                    not exceeding $1,450,000 in the aggregate at any time
                    outstanding with respect to obligations of Murex
                    Biotech S.A. (Pty) Limited in connection with the
                    construction of a manufacturing facility in South
                    Africa, and (ii) IMTC or any Material Subsidiary after
                    the Agreement Date with respect to any other
                    obligations of an Affiliate of IMTC and not exceeding
                    $1,000,000 in the aggregate at any time outstanding."

               4.   Amendment to Section 8.18.  Section 8.18 of the Credit
                    -------------------------
          Agreement, Capital Expenditures, is hereby deleted in its
                     --------------------
          entirety and replaced with the following:

                    "8.18  Capital Expenditures.  IMTC and its Subsidiaries
                           --------------------
               shall not make or incur during (a) the fiscal year ending on
               December 31, 1997, in the aggregate any Capital Expenditures
               in excess of $10,500,000 and (b) the fiscal year ending on
               December 31, 1998, and during each fiscal year thereafter,
               in the aggregate any Capital Expenditures in excess of
               $7,000,000."

               5.   No Other Amendment.  Except for the amendments
                    ------------------
          expressly set forth above, the text of the Credit Agreement and
          all other Loan Documents shall remain unchanged and in full force
          and effect.  Each Borrower acknowledges and expressly agrees that
          the Lenders reserve the right to, and do in fact, require strict
          compliance with all terms and provisions of the Credit Agreement
          and the other Loan Documents.

               6.   Representations and Warranties.  Each Borrower hereby
                    ------------------------------
          represents and warrants in favor of the Agent, the Issuing Banks,
          and each Lender, as follows:

                    (a)  such Borrower has the corporate power and
               authority (i) to enter into this Amendment, and (ii) to do
               all acts and things as are required or contemplated
               hereunder to be done, observed and performed by it;

                    (b)  this Amendment has been duly authorized, validly
               executed and delivered by one or more authorized signatories
               of such Borrower, and constitutes the legal, valid and
               binding obligation of the Borrower, enforceable against such
               Borrower in accordance with its terms;

                    (c)  the execution and delivery of this Amendment and
               performance by such Borrower under the Credit Agreement, as
               amended hereby, do not and will not require the consent or
               approval of any regulatory authority or governmental
               authority or agency having jurisdiction over such Borrower
               which has not already been obtained, nor contravene or
               conflict with the charter documents of such Borrower, or the
               provisions of any statute, judgment, order, indenture,
               instrument, agreement or undertaking, to which such Borrower
               is a party or by which any of its properties are or may
               become bound; and

                    (d)  as of the date hereof, and after giving effect to
               this Amendment (i) no Default or Event of Default exists
               under the Credit Agreement or is caused by this Amendment,
               and (ii) each presentation and warranty set forth in Article
               VI of the Credit Agreement is true and correct in all
               material respects, except (x) to the extent previously
               fulfilled in accordance with the terms of the Credit
               Agreement, as amended hereby, or (y) to the extent
               specifically relating to the Agreement Date.

               7.   Loan Document.  This Amendment shall be deemed to be a
                    -------------
          Loan Document for all purposes.

               8.   Expenses.  The Borrowers agree to pay all reasonable
                    --------
          expenses of the Agent incurred in connection with this Amendment,
          including, without limitation, all fees and expenses of counsel
          to the Agent.

               9.   Counterparts.  This Amendment may be executed in
                    ------------
          multiple counterparts, each of which shall be deemed to be an
          original and all of which, taken together, shall constitute one
          and the same agreement.  Delivery of an executed counterpart of
          this Amendment by facsimile transmission shall be as effective as
          delivery of a manually executed counterpart hereof.

               10.  Governing Law.  This Amendment shall be deemed to be
                    -------------
          made pursuant to the laws of the State of Georgia with respect to
          agreements made and to be performed wholly in the State of
          Georgia, and shall be construed, interpreted, performed and
          enforced in accordance therewith.

               11.  Definitions.  All capitalized terms not otherwise
                    -----------
          defined herein shall have the meanings set forth in the Credit
          Agreement.

               12.  Effectiveness.  This Amendment shall be effective as of
                    -------------
          the date first set forth above upon the Agent's receipt of a
          counterpart hereof duly executed by the Borrowers, the Issuing
          Banks and the Lenders.


                  [REMAINDER OF THIS PAGE INTENTIONALLY LEFT BLANK]




          <PAGE>


                    IN WITNESS WHEREOF, the parties hereto have executed
          this Amendment or caused it to be executed by their duly
          authorized officers, effective as of the day and year first
          written above.


          BORROWERS:                    INTERNATIONAL MUREX TECHNOLOGIES
                                        CORPORATION

                                        By:  /s/ Steven C. Ramsey
                                           ----------------------------
                                        Title:     CFO
                                              -------------------------


                                        MUREX DIAGNOSTICS INTERNATIONAL,
                                        INC.

                                        By:   /s/ Steven C. Ramsey
                                           ---------------------------
                                        Title:     Director
                                              ------------------------


                                        MUREX DIAGNOSTICS CORPORATION

                                        By:    /s/ Steven C. Ramsey
                                           ---------------------------
                                        Title:   Director
                                              ------------------------


                                        IMTC HOLDINGS (UK) LIMITED

                                        By:   /s/ Steven C. Ramsey
                                           ---------------------------
                                        Title:   Director
                                              ------------------------


                                        MUREX DIAGNOSTICS, INC.

                                        By:   /s/ Steven C. Ramsey
                                           ----------------------------
                                        Title:    VP Finance
                                              -------------------------


                                        MUREX BIOTECH LIMITED

                                        By:   /s/ Steven C. Ramsey
                                           -----------------------------
                                        Title:    Director
                                              --------------------------


          AGENT:                        BANK OF AMERICA, FSB

                                        By:   /s/ John Yankavskas
                                           -----------------------------
                                        Title:    V.P.
                                              --------------------------


          LENDERS:                      BANK OF AMERICA, FSB

                                        By:  /s/ John Yankavskas
                                           ------------------------------
                                        Title:   V.P.
                                              ---------------------------


                                        BANK OF AMERICA NATIONAL TRUST AND
                                        SAVINGS ASSOCIATION, acting through
                                        its London Branch

                                        By:   /s/ Keith Thomas
                                           ------------------------------
                                        Title:    Vice President
                                              ---------------------------


          ISSUING BANKS:                BANK OF AMERICA NATIONAL TRUST AND
                                        SAVINGS ASSOCIATION

                                        By:   /s/ Ginger Trimble
                                           ------------------------------
                                        Title:    Vice President
                                              ---------------------------


                                        BANK OF AMERICA NATIONAL TRUST AND
                                        SAVINGS ASSOCIATION, acting through
                                        its London Branch

                                        By:   /s/ Keith Thomas
                                           ------------------------------
                                        Title:    Vice President
                                              ---------------------------


INTERNATIONAL MUREX TECHNOLOGIES CORPORATION                         Exhibit  21
Subsidiaries as of December 31, 1997


- --------------------------------------------------------------------------------

                                                                 Jurisdiction of
Name                                                              Incorporation
- --------------------------------------------------------------------------------

SUBSIDIARIES OF INTERNATIONAL MUREX TECHNOLOGIES CORPORATION

IMTC Holdings (U.K.) Limited                                      United Kingdom

Specialist Diagnostics Limited                                    United Kingdom

Murex Biotech Limited                                             United Kingdom

Murex Diagnostics Corporation                                     Barbados

Murex Diagnostics International, Inc.                             Barbados

Murex Diagnosticos Ltda                                           Brazil

IMTC Holdings Corporation (L) Limited                             Malaysia

IMTC Holdings BV                                                  Netherlands

Murex Diagnostics Benelux BV                                      Netherlands

Murex Diagnostici, S.p.A                                          Italy

Murex Diagnostics France S.A                                      France

Murex Diagnostic S.A                                              Spain

Murex Diagnostica GmbH                                            Germany

Murex Diagnostics A/S                                             Denmark

Murex Diagnostics, Spol. s r.o                                    Czech Republic

Murex Diagnostics, Inc.                                           United States

IMTC Technologies, Inc.                                           United States

Murex Medical Research Limited                                    Isle of Man

Technology Licence Company Limited                                Isle of Man

Murex Diagnostics Australia Pty Ltd.                              Australia

Murex Diagnostics Private Limited                                 Singapore

Murex Argentina S.A                                               Argentina

Murex Diagnostics SA (Pty.) Limited                               South Africa

Murex Biotech SA (Pty.) Limited                                   South Africa





                                
                               POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----


                                        /s/ C. Robert Cusick
                                        -----------------------------
                                             C. Robert Cusick

     <PAGE>


                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----  




                                    /s/ F. Michael P. Warren
                                   ---------------------------------
                                        F. Michael P. Warren

     <PAGE>


                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----



                                    /s/ J. Trevor Eyton
                                   --------------------------------
                                        J. Trevor Eyton

     <PAGE>


                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----




                                    /s/ Thomas L. Gavin
                                   --------------------------------
                                        Thomas L. Gavan

     <PAGE>

                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----



                                    /s/ Norbert J. Gilmore
                                   --------------------------------
                                        Norbert J. Gilmore

     <PAGE>


                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----


                                        /s/ Hartland M. MacDougall
                                        -----------------------------
                                             Hartland M. MacDougall


     <PAGE>

                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----  




                                    /s/ Jay A. Lefton
                                   ---------------------------------
                                        Jay A. Lefton

     <PAGE>

                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----



                                    /s/ Stanley E. Read
                                   --------------------------------
                                        Stanley E. Read


     <PAGE>

                                  POWER OF ATTORNEY


               KNOW ALL MEN BY THESE PRESENTS that the undersigned
          constitutes and appoints Steven C. Ramsey his true and lawful
          attorney-in-fact and agent, with full power of substitution and
          resubstitution, for him and in his name, place and stead, in any
          and all capacities, to sign the Annual Report on Form 10-K of
          International Murex Technologies Corporation, a British Columbia
          corporation, for the year ended December 31, 1997, any or all
          amendments and supplements, to file the same, with all exhibits
          thereto, and other documents in connection therewith, with the
          Securities and Exchange Commission and the Nasdaq National Market
          System, granting unto said attorney-in-fact and agent full power
          and authority to do and perform each and every act and thing
          requisite and necessary to be done in and about the premises, as
          fully to all intents and purposes as he might or could do in
          person, hereby ratifying and confirming all that said attorney-
          in-fact and agent or his substitute or substitutes may lawfully
          do or cause to be done by virtue hereof.

               DATED March 9, 1998
                          ----




                                    /s/ Victor A. Rice
                                   --------------------------------
                                        Victor A. Rice





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