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<PAGE> PAGE 7
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<PAGE> PAGE 8
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<PAGE> PAGE 10
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<PAGE> PAGE 11
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<PAGE> PAGE 12
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<PAGE> PAGE 14
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<PAGE> PAGE 15
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<PAGE> PAGE 16
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<PAGE> PAGE 17
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<PAGE> PAGE 18
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<PAGE> PAGE 20
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<PAGE> PAGE 21
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<PAGE> PAGE 22
036 B000500 0
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<PAGE> PAGE 23
070 C010500 Y
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070 G020500 N
070 H010500 N
070 H020500 N
070 I010500 N
070 I020500 N
070 J010500 N
070 J020500 N
070 K010500 N
070 K020500 N
070 L010500 N
070 L020500 N
070 M010500 N
070 M020500 N
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070 O010500 N
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<PAGE> PAGE 24
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<PAGE> PAGE 25
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<PAGE> PAGE 26
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<PAGE> PAGE 27
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<PAGE> PAGE 28
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<PAGE> PAGE 29
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<PAGE> PAGE 30
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<PAGE> PAGE 31
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<PAGE> PAGE 32
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<PAGE> PAGE 33
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<PAGE> PAGE 34
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<PAGE> PAGE 35
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<PAGE> PAGE 36
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<PAGE> PAGE 37
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<PAGE> PAGE 38
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<PAGE> PAGE 39
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<PAGE> PAGE 40
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<PAGE> PAGE 41
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<PAGE> PAGE 42
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<PAGE> PAGE 43
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<PAGE> PAGE 44
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SIGNATURE BARRY FINK
TITLE VICE PRESIDENT
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MSDW MULTI-STATE MUNICIPAL SERIES TRUST - MINNESOTA SERIES
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
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<PERIOD-END> NOV-30-1999
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<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 426,128
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<EXPENSES-NET> (89,590)
<NET-INVESTMENT-INCOME> 336,538
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<NUMBER-OF-SHARES-REDEEMED> (154,345)
<SHARES-REINVESTED> 18,774
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<PER-SHARE-DIVIDEND> (0.44)
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<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.03
<EXPENSE-RATIO> 1.13
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
Morgan Stanley Dean Witter Multi-Series Municipal Trust-California
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
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<TOTAL-LIABILITIES> (193,857)
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<ACCUM-APPREC-OR-DEPREC> (831,560)
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<EXPENSES-NET> (615,515)
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<SHARES-REINVESTED> 308,057
<NET-CHANGE-IN-ASSETS> (9,660,134)
<ACCUMULATED-NII-PRIOR> 0
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<GROSS-ADVISORY-FEES> (356,813)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (620,582)
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<PER-SHARE-NII> 0.52
<PER-SHARE-GAIN-APPREC> (0.85)
<PER-SHARE-DIVIDEND> (0.52)
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<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.18
<EXPENSE-RATIO> 0.61
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
Morgan Stanley Dean Witter Multi-series Municipal Series Trust-Massachusetts
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 11,660,050
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<OTHER-ITEMS-LIABILITIES> (26,095)
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<ACCUM-APPREC-OR-DEPREC> 134,082
<NET-ASSETS> 12,028,564
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<EXPENSES-NET> (120,330)
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<NUMBER-OF-SHARES-SOLD> 107,144
<NUMBER-OF-SHARES-REDEEMED> (346,276)
<SHARES-REINVESTED> 45,969
<NET-CHANGE-IN-ASSETS> (3,207,526)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 171,067
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<GROSS-ADVISORY-FEES> (49,848)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (121,552)
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<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.75)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> (0.13)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.45
<EXPENSE-RATIO> 0.85
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
Morgan Stanley Dean Witter Multi-Series Municipal Series Trust-Michigan
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 15,073,064
<INVESTMENTS-AT-VALUE> 14,906,029
<RECEIVABLES> 167,541
<ASSETS-OTHER> 376,086
<OTHER-ITEMS-ASSETS> 0
<TOTAL-ASSETS> 15,449,656
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<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> (23,458)
<TOTAL-LIABILITIES> (23,458)
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 15,624,705
<SHARES-COMMON-STOCK> 1,537,836
<SHARES-COMMON-PRIOR> 1,587,214
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (31,472)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> (167,035)
<NET-ASSETS> 15,426,198
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<OTHER-INCOME> 0
<EXPENSES-NET> (140,366)
<NET-INVESTMENT-INCOME> 758,022
<REALIZED-GAINS-CURRENT> (31,471)
<APPREC-INCREASE-CURRENT> (1,120,780)
<NET-CHANGE-FROM-OPS> (394,229)
<EQUALIZATION> 0
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<DISTRIBUTIONS-OF-GAINS> (694,270)
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<NUMBER-OF-SHARES-SOLD> 148,075
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<NET-CHANGE-IN-ASSETS> (2,333,012)
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<ACCUMULATED-GAINS-PRIOR> 694,269
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<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (58,834)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (141,823)
<AVERAGE-NET-ASSETS> 16,809,608
<PER-SHARE-NAV-BEGIN> 11.19
<PER-SHARE-NII> 0.48
<PER-SHARE-GAIN-APPREC> (0.73)
<PER-SHARE-DIVIDEND> (0.48)
<PER-SHARE-DISTRIBUTIONS> (0.43)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.03
<EXPENSE-RATIO> 0.84
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MORGAN STANLEY DEAN WITTER MULTI-STATE MUNICIPAL SERIES TRUST - OHIO
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 15,681,956
<INVESTMENTS-AT-VALUE> 15,596,638
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<TOTAL-ASSETS> 16,176,396
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<OTHER-ITEMS-LIABILITIES> (24,051)
<TOTAL-LIABILITIES> (517,056)
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 15,786,140
<SHARES-COMMON-STOCK> 1,524,259
<SHARES-COMMON-PRIOR> 1,666,037
<ACCUMULATED-NII-CURRENT> 0
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<ACCUMULATED-NET-GAINS> (41,482)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> (85,318)
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<OTHER-INCOME> 0
<EXPENSES-NET> (140,296)
<NET-INVESTMENT-INCOME> 822,837
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<DISTRIBUTIONS-OF-INCOME> (822,837)
<DISTRIBUTIONS-OF-GAINS> (219,842)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 247,224
<NUMBER-OF-SHARES-REDEEMED> (447,444)
<SHARES-REINVESTED> 58,442
<NET-CHANGE-IN-ASSETS> (2,920,966)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 218,211
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<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (61,383)
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<GROSS-EXPENSE> (141,835)
<AVERAGE-NET-ASSETS> 17,538,106
<PER-SHARE-NAV-BEGIN> 11.15
<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.75)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> (0.13)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.27
<EXPENSE-RATIO> 0.81
</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MSDW MULTI-STATE ARIZONA
</LEGEND>
<S> <C>
<PERIOD-TYPE> 6-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 36,594,276
<INVESTMENTS-AT-VALUE> 36,114,335
<RECEIVABLES> 747,734
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<OTHER-ITEMS-ASSETS> 10,092
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<SENIOR-LONG-TERM-DEBT> (34,253)
<OTHER-ITEMS-LIABILITIES> (11,377)
<TOTAL-LIABILITIES> (45,630)
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 37,416,253
<SHARES-COMMON-STOCK> 3,722,888
<SHARES-COMMON-PRIOR> 3,852,209
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<ACCUMULATED-NET-GAINS> (69,118)
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<ACCUM-APPREC-OR-DEPREC> (479,941)
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<OTHER-INCOME> 0
<EXPENSES-NET> (264,280)
<NET-INVESTMENT-INCOME> 1,900,085
<REALIZED-GAINS-CURRENT> (69,115)
<APPREC-INCREASE-CURRENT> (2,859,823)
<NET-CHANGE-FROM-OPS> (1,028,853)
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<DISTRIBUTIONS-OF-GAINS> (609,152)
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<NUMBER-OF-SHARES-SOLD> 375,871
<NUMBER-OF-SHARES-REDEEMED> (632,656)
<SHARES-REINVESTED> 127,464
<NET-CHANGE-IN-ASSETS> (4,788,016)
<ACCUMULATED-NII-PRIOR> 0
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<GROSS-EXPENSE> (266,736)
<AVERAGE-NET-ASSETS> 40,219,546
<PER-SHARE-NAV-BEGIN> 10.81
<PER-SHARE-NII> 0.49
<PER-SHARE-GAIN-APPREC> (0.75)
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<PER-SHARE-DISTRIBUTIONS> (0.16)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 9.90
<EXPENSE-RATIO> 0.66
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
multy-state new-york
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 10,442,285
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<EXPENSES-NET> (105,143)
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<NUMBER-OF-SHARES-REDEEMED> (115,169)
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<GROSS-EXPENSE> (106,195)
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<PER-SHARE-NAV-BEGIN> 11.41
<PER-SHARE-NII> 0.49
<PER-SHARE-GAIN-APPREC> (0.80)
<PER-SHARE-DIVIDEND> (0.49)
<PER-SHARE-DISTRIBUTIONS> (0.37)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.24
<EXPENSE-RATIO> 0.93
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MDSW MULTI-STATE Florida Series
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOVEMBER 30, 1999
<PERIOD-END> NOVEMBER 30, 1999
<INVESTMENTS-AT-COST> 51,810,954
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<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (203,267)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (369,670)
<AVERAGE-NET-ASSETS> 58,076,137
<PER-SHARE-NAV-BEGIN> 11.25
<PER-SHARE-NII> 0.50
<PER-SHARE-GAIN-APPREC> (0.78)
<PER-SHARE-DIVIDEND> (0.50)
<PER-SHARE-DISTRIBUTIONS> (0.37)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.10
<EXPENSE-RATIO> 0.64
</TABLE>
WARNING: THE EDGAR SYSTEM ENCOUNTERED ERROR(S) WHILE PROCESSING THIS SCHEDULE.
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MULTI-STATE PENNSYLVANIA
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 49,599,777
<INVESTMENTS-AT-VALUE> 48,310,538
<RECEIVABLES> 830,485
<ASSETS-OTHER> 20,678
<OTHER-ITEMS-ASSETS> 8,863
<TOTAL-ASSETS> 49,170,564
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> (111,450)
<TOTAL-LIABILITIES> (111,450)
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 50,355,003
<SHARES-COMMON-STOCK> 4,813,564
<SHARES-COMMON-PRIOR> 4,825,122
<ACCUMULATED-NII-CURRENT> (6,650)
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (6,646)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> (1,289,239)
<NET-ASSETS> 49,059,114
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2,870,676
<OTHER-INCOME> 0
<EXPENSES-NET> 333,564
<NET-INVESTMENT-INCOME> 2,537,112
<REALIZED-GAINS-CURRENT> (6,646)
<APPREC-INCREASE-CURRENT> (4,132,749)
<NET-CHANGE-FROM-OPS> (1,602,283)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (2,537,112)
<DISTRIBUTIONS-OF-GAINS> (578,726)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 359,418
<NUMBER-OF-SHARES-REDEEMED> (560,476)
<SHARES-REINVESTED> 189,500
<NET-CHANGE-IN-ASSETS> (4,749,133)
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 578,722
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (183,815)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (336,320)
<AVERAGE-NET-ASSETS> 52,518,567
<PER-SHARE-NAV-BEGIN> 11.15
<PER-SHARE-NII> 0.52
<PER-SHARE-GAIN-APPREC> (0.84)
<PER-SHARE-DIVIDEND> (0.52)
<PER-SHARE-DISTRIBUTIONS> (0.12)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.19
<EXPENSE-RATIO> 0.64
</TABLE>
<TABLE> <S> <C>
<ARTICLE> 6
<LEGEND>
MSDW MULTI-STATE NEW JERSEY
</LEGEND>
<S> <C>
<PERIOD-TYPE> 12-MOS
<FISCAL-YEAR-END> NOV-30-1999
<PERIOD-END> NOV-30-1999
<INVESTMENTS-AT-COST> 38180691
<INVESTMENTS-AT-VALUE> 37982832
<RECEIVABLES> 695058
<ASSETS-OTHER> 8378
<OTHER-ITEMS-ASSETS> 113449
<TOTAL-ASSETS> 38799717
<PAYABLE-FOR-SECURITIES> 0
<SENIOR-LONG-TERM-DEBT> 0
<OTHER-ITEMS-LIABILITIES> (233335)
<TOTAL-LIABILITIES> (233335)
<SENIOR-EQUITY> 0
<PAID-IN-CAPITAL-COMMON> 38833385
<SHARES-COMMON-STOCK> 3772932
<SHARES-COMMON-PRIOR> 3750154
<ACCUMULATED-NII-CURRENT> 0
<OVERDISTRIBUTION-NII> 0
<ACCUMULATED-NET-GAINS> (69144)
<OVERDISTRIBUTION-GAINS> 0
<ACCUM-APPREC-OR-DEPREC> (197859)
<NET-ASSETS> 38566382
<DIVIDEND-INCOME> 0
<INTEREST-INCOME> 2205912
<OTHER-INCOME> 0
<EXPENSES-NET> (279155)
<NET-INVESTMENT-INCOME> 1926757
<REALIZED-GAINS-CURRENT> (69142)
<APPREC-INCREASE-CURRENT> (2840301)
<NET-CHANGE-FROM-OPS> (982686)
<EQUALIZATION> 0
<DISTRIBUTIONS-OF-INCOME> (1926757)
<DISTRIBUTIONS-OF-GAINS> (609503)
<DISTRIBUTIONS-OTHER> 0
<NUMBER-OF-SHARES-SOLD> 362856
<NUMBER-OF-SHARES-REDEEMED> (478651)
<SHARES-REINVESTED> 138573
<NET-CHANGE-IN-ASSETS> 22778
<ACCUMULATED-NII-PRIOR> 0
<ACCUMULATED-GAINS-PRIOR> 609501
<OVERDISTRIB-NII-PRIOR> 0
<OVERDIST-NET-GAINS-PRIOR> 0
<GROSS-ADVISORY-FEES> (142574)
<INTEREST-EXPENSE> 0
<GROSS-EXPENSE> (281460)
<AVERAGE-NET-ASSETS> 40735546
<PER-SHARE-NAV-BEGIN> 11.15
<PER-SHARE-NII> 0.51
<PER-SHARE-GAIN-APPREC> (0.77)
<PER-SHARE-DIVIDEND> (0.51)
<PER-SHARE-DISTRIBUTIONS> (0.16)
<RETURNS-OF-CAPITAL> 0
<PER-SHARE-NAV-END> 10.22
<EXPENSE-RATIO> 0.69
</TABLE>
<TABLE>
<CAPTION>
EXHIBIT 77(O) MORGAN STANLEY DEAN WITTER MULTI-STATE MUNICIPAL SERIES-OHIO
10f-3 transactions for the period July 29,1999-December 31, 1999
<S> <C> <C> <C> <C> <C> <C> <C>
TOTAL
ISSUED/
DATE PRICE SHARES % of PRINCIPAL PURCHASED
SECURITY PURCHASED SHARE PURCHASED Assets AMOUNT BY GROUP BROKER(S)
Ohio Building Authority 07/01/99 $97.86 500,000 2.901% $150,000,000.00 0.333% Paine Webber
</TABLE>
To the Shareholders and Board of Directors of
XYZ Fund
(2)
Report of Independent Accountants
To the Shareholders and Trustees of
Morgan Stanley Dean Witter Multi-State Municipal Series Trust
In planning and performing our audit of the financial statements
of the Arizona Series, the California Series, the Florida
Series, the Massachusetts Series, the Michigan Series, the
Minnesota Series, the New Jersey Series, the New York Series,
the Ohio Series and the Pennsylvania Series (constituting the
Morgan Stanley Dean Witter Multi-State Municipal Series Trust,
hereafter referred to as the "Fund") for the year ended November
30, 1999, we considered its internal control, including control
activities for safeguarding securities, in order to determine
our auditing procedures for the purpose of expressing our
opinion on the financial statements and to comply with the
requirements of Form N-SAR, not to provide assurance on internal
control.
The management of the Fund is responsible for establishing and
maintaining internal control. In fulfilling this
responsibility, estimates and judgments by management are
required to assess the expected benefits and related costs of
controls. Generally, controls that are relevant to an audit
pertain to the entity's objective of preparing financial
statements for external purposes that are fairly presented in
conformity with generally accepted accounting principles. Those
controls include the safeguarding of assets against unauthorized
acquisition, use or disposition.
Because of inherent limitations in internal control, errors or
fraud may occur and not be detected. Also, projection of any
evaluation of internal control to future periods is subject to
the risk that controls may become inadequate because of changes
in conditions or that the effectiveness of their design and
operation may deteriorate.
Our consideration of internal control would not necessarily
disclose all matters in internal control that might be material
weaknesses under standards established by the American Institute
of Certified Public Accountants. A material weakness is a
condition in which the design or operation of one or more of the
internal control components does not reduce to a relatively low
level the risk that misstatements caused by error or fraud in
amounts that would be material in relation to the financial
statements being audited may occur and not be detected within a
timely period by employees in the normal course of performing
their assigned functions. However, we noted no matters
involving internal control and its operation, including controls
for safeguarding securities, that we consider to be material
weaknesses as defined above as of November 30, 1999.
This report is intended solely for the information and use of
the Trustees, management and the Securities and Exchange
Commission and is not intended to be and should not be used by
anyone other than these specified parties.
January 26, 2000
