FRANKLIN STRATEGIC SERIES
497, 1998-02-24
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                       SUPPLEMENT DATED FEBRUARY 24, 1998
                              TO THE PROSPECTUS OF

                        Franklin Global Health Care Fund
                             dated September 1, 1997

The prospectus is amended as follows:

I.    The following paragraph is added to the end of the section "Group
Purchases - Class I Only" found under "How Do I Buy Shares? - Sales Charge
Reductions and Waivers:"

      A qualified  group does not include a 403(b) plan that only allows  salary
      deferral  contributions.  403(b)  plans  that only allow  salary  deferral
      contributions  and that purchased  Class I shares of the Fund at a reduced
      sales charge under the group purchase  privilege  before February 1, 1998,
      however, may continue to do so.

II. The first two paragraphs and the first waiver category in the section "Sales
Charge Waivers," found under "How Do I Buy Shares? - Sales Charge Reductions and
Waivers," are replaced with the following:

      Sales Charge Waivers. If one of the following sales charge waivers applies
      to you or your  purchase  of Fund  shares,  you may buy shares of the Fund
      without a front-end  sales charge or a Contingent  Deferred  Sales Charge.
      All of the sales charge waivers listed below apply to purchases of Class I
      shares  only,  except  for  items 1 and 4 which  also  apply  to  Class II
      purchases.

      Certain distributions, payments or redemption proceeds that you receive
      may be used to buy shares of the Fund without a sales charge if you
      reinvest them within 365 days of their payment or redemption date. They
      include:

      1. Dividend and capital  gain  distributions  from any Franklin  Templeton
         Fund or a real estate  investment  trust (REIT) sponsored or advised by
         Franklin   Properties,   Inc.  The  distributions   generally  must  be
         reinvested  in the same  class of  shares.  Certain  exceptions  apply,
         however,   to  Class  II  shareholders  who  chose  to  reinvest  their
         distributions  in Class I shares of the Fund before  November 17, 1997,
         and to Advisor Class or Class Z  shareholders  of a Franklin  Templeton
         Fund who may  reinvest  their  distributions  in Class I shares  of the
         Fund.

III. The  following  new category 5 is added to the list of sales charge  waiver
categories  in the section  "Sales  Charge  Waivers,"  found under "How Do I Buy
Shares? - Sales Charge Reductions and Waivers." The waiver  categories  numbered
five through 15 in the prospectus are renumbered accordingly:

      5. Redemption  proceeds  from the  sale of  Class A  shares  of any of the
         Templeton Global Strategy Funds if you are a qualified investor.

         If you paid a contingent  deferred  sales charge when you redeemed your
         Class A shares from a Templeton  Global  Strategy  Fund,  a  Contingent
         Deferred  Sales Charge will apply to your purchase of Fund shares and a
         new Contingency Period will begin. We will,  however,  credit your Fund
         account with additional  shares based on the contingent  deferred sales
         charge  you paid and the  amount of the  redemption  proceeds  that you
         reinvest.

         If you  immediately  placed  your  redemption  proceeds  in a  Franklin
         Templeton  money fund,  you may reinvest them as described  above.  The
         proceeds  must be  reinvested  within  365 days  from the date they are
         redeemed from the money fund.

IV.   The section "Retirement Plans," found under "How Do I Buy Shares? -
Sales Charge Reductions and Waivers," is replaced in its entirety with the
following:

      Retirement  Plans.  Retirement plans that (i) are sponsored by an employer
      with at least 100  employees,  or (ii) have plan  assets of $1  million or
      more, or (iii) agree to invest at least $500,000 in the Franklin Templeton
      Funds over a 13 month  period may buy Class I shares  without a  front-end
      sales charge.  Retirement plans that are not Qualified  Retirement  Plans,
      SIMPLEs or SEPs must also meet the  requirements  described  under  "Group
      Purchases - Class I Only" above to be able to buy Class I shares without a
      front-end  sales charge.  We may enter into a special  arrangement  with a
      Securities  Dealer,  based on  criteria  established  by the Fund,  to add
      together certain small Qualified  Retirement Plan accounts for the purpose
      of meeting these requirements.

      For retirement  plan accounts opened on or after May 1, 1997, a Contingent
      Deferred Sales Charge may apply if the retirement  plan is transferred out
      of the  Franklin  Templeton  Funds or  terminated  within  365 days of the
      retirement  plan  account's  initial  purchase in the  Franklin  Templeton
      Funds. Please see "How Do I Sell Shares? Contingent Deferred Sales Charge"
      for details.

V. The  following  paragraph  is added at the end of the  section  "How Do I Buy
Shares?":

      For Investors Outside the U.S.

      The distribution of this prospectus and the offering of Fund shares may be
      limited in many jurisdictions. An investor who wishes to buy shares of the
      Fund should determine, or have a broker-dealer  determine,  the applicable
      laws  and  regulations  of  the  relevant   jurisdiction.   Investors  are
      responsible   for  compliance  with  tax,   currency   exchange  or  other
      regulations  applicable to  redemption  and purchase  transactions  in any
      jurisdiction  to  which  they may be  subject.  Investors  should  consult
      appropriate  tax and legal  advisors  to obtain  information  on the rules
      applicable to these transactions.

VI. The sections  "Contingent  Deferred Sales Charge - Class I" and  "Contingent
Deferred Sales Charge - Class II," found under "May I Exchange Shares for Shares
of Another Fund? - Will Sales Charges Apply to My Exchange?",  are replaced with
the following:

      Contingent  Deferred  Sales Charge.  For accounts with shares subject to a
      Contingent  Deferred  Sales Charge,  we will first  exchange any shares in
      your account  that are not subject to the charge.  If there are not enough
      of these to meet your exchange request, we will exchange shares subject to
      the charge in the order they were purchased.

      If you exchange Class I shares into one of our money funds,  the time your
      shares are held in that fund will not count towards the  completion of any
      Contingency  Period.  If you  exchange  your Class II shares for shares of
      Money Fund II,  however,  the time your  shares are held in that fund will
      count towards the completion of any Contingency Period.

VII.  The following replaces the second paragraph found under "How Do I Sell
Shares? - Contingent Deferred Sales Charge:"

      Certain  retirement plan accounts opened on or after May 1, 1997, and that
      qualify to buy Class I shares without a front-end sales charge may also be
      subject to a Contingent  Deferred Sales Charge if the  retirement  plan is
      transferred out of the Franklin  Templeton Funds or terminated  within 365
      days of the account's initial purchase in the Franklin Templeton Funds.

VIII.  Under "What  Distributions  Might I Receive from the Fund? - Distribution
Options," the  references in the first two paragraphs to the ability of Class II
shareholders to reinvest or direct their  distributions to Class I shares of the
Fund or another Franklin Templeton Fund are deleted and the following  paragraph
is added to the section:

      Distributions  may be reinvested only in the same class of shares,  except
      as  follows:  (i)  Class  II  shareholders  who  chose to  reinvest  their
      distributions in Class I shares of the Fund or another Franklin  Templeton
      Fund before  November 17,  1997,  may continue to do so; and (ii) Class II
      shareholders  may reinvest their  distributions  in shares of any Franklin
      Templeton money fund.

IX. The  following  definition  is added to the "Useful  Terms and  Definitions"
section:

      SIMPLE  (Savings  Incentive  Match  Plan  for  Employees)  -  An  employer
      sponsored  salary  deferral plan  established  under section 408(p) of the
      Code



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