FRANKLIN STRATEGIC SERIES
497, 2000-12-01
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* FSS2 P-1

                        SUPPLEMENT DATED DECEMBER 1, 2000
                              TO THE PROSPECTUS OF

                            FRANKLIN STRATEGIC SERIES
     (FSS2-FRANKLIN BIOTECHNOLOGY DISCOVERY, TECHNOLOGY, GLOBAL HEALTH CARE,
               GLOBAL COMMUNICATIONS AND NATURAL RESOURCES FUNDS)
                             DATED SEPTEMBER 1, 2000

The prospectus is amended as follows:

I. The "Management" section on page 10 is replaced with the following:

 [Insert graphic of briefcase] MANAGEMENT
                               ----------

 Franklin Advisers, Inc. (Advisers),  777 Mariners Island Blvd., San Mateo, CA
 94403,  is  the  Fund's  investment  manager.  Together,   Advisers  and  its
 affiliates manage over $229 billion in assets.

       The team responsible for the Fund's management is:

       EVAN MCCULLOCH CFA, VICE PRESIDENT OF ADVISERS
       Mr.  McCulloch  has been a manager  of the Fund since  1997.  He joined
       Franklin Templeton Investments in 1992.

       PAUL WALKER CFA, PORTFOLIO MANAGER OF ADVISERS
       Mr.  Walker has been a manager  of the Fund  since May 2000.  He joined
       Franklin Templeton Investments in 1996.

       JASON R. NUNN, PORTFOLIO MANAGER OF ADVISERS
       Mr. Nunn has been a manager of the Fund since  November 2000. He joined
       Franklin  Templeton  Investments  in 1998.  Previously,  he  worked  in
       corporate finance with Alex. Brown & Sons.

       The Fund pays  Advisers a fee for managing the Fund's  assets.  For the
       fiscal  year ended April 30,  2000,  the Fund paid 0.47% of its average
       daily net assets to the manager for its services.

II. The "Management" section on page 30 is replaced with the following:

 [Insert graphic of briefcase] MANAGEMENT
                               ----------

 Franklin Advisers, Inc. (Advisers),  777 Mariners Island Blvd., San Mateo, CA
 94403,  is  the  Fund's  investment  manager.  Together,   Advisers  and  its
 affiliates manage over $229 billion in assets.

       The team responsible for the Fund's management is:

       JASON R. NUNN, PORTFOLIO MANAGER OF ADVISERS
       Mr. Nunn has been a manager of the Fund since  November 2000. He joined
       Franklin  Templeton  Investments  in 1998.  Previously,  he  worked  in
       corporate finance with Alex. Brown & Sons.

       EVAN MCCULLOCH CFA, VICE PRESIDENT OF ADVISERS
       Mr.  McCulloch  has been a manager  of the Fund since  1994.  He joined
       Franklin Templeton Investments in 1992.

       PAUL WALKER CFA, PORTFOLIO MANAGER OF ADVISERS
       Mr.  Walker  has been a manager  of the Fund since  November  2000.  He
       joined Franklin Templeton Investments in 1996.

       RUPERT H. JOHNSON, JR., PRESIDENT OF ADVISERS
       Mr.  Johnson  has been a  manager  of the Fund  since  1992.  He joined
       Franklin Templeton Investments in 1965.

       The Fund pays  Advisers a fee for managing the Fund's  assets.  For the
       fiscal year ended April 30, 2000,  management fees,  before any advance
       waiver  were 0.62% of the Fund's  average  daily net  assets.  Under an
       agreement  by the  manager  to  reduce  its  fees  to  reflect  reduced
       services  resulting from the Fund's investment in a Franklin  Templeton
       money fund,  the Fund paid 0.61% of its average daily net assets to the
       manager  for its  services.  This  reduction  is required by the Fund's
       Board  of  Trustees  and  an  order  by  the  Securities  and  Exchange
       Commission.



               Please keep this supplement for future reference.>





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