MEDIMMUNE INC /DE
SC 13D, 1998-02-02
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                                                             Page 1 of 37 pages.

                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                 ---------------

                                  SCHEDULE 13D

                            Pursuant to Section 13(d)
                     of the Securities Exchange Act of 1934

                                 ---------------

                                 MedImmune, Inc.
                                (Name of Issuer)

                                 ---------------

                          Common Stock, $.01 Par Value
                         (Title of Class of Securities)

                                 ---------------

                                   584699-10-2
                      (Cusip Number of Class of Securities)

                                 ---------------

               Fredrik Nilert, Investor International (U.S.), Inc.
                       320 Park Avenue, New York, NY 10022
                                 (212) 508-0900
           (Name, Address and Telephone Number of Person Authorized to
                       Receive Notices and Communications)

                                 ---------------

                                    Copy to:

                             Robert P. Zinn, Esquire
                           Kirkpatrick & Lockhart LLP
                   1500 Oliver Building, Pittsburgh, PA 15222
                            Telephone: (412) 335-8687

                                 ---------------

                                January 21, 1998
             (Date of Event which Requires Filing of this Statement)

         If the filing person has  previously  filed a Statement on Schedule 13G
to report the  acquisition  which is the subject of this  Schedule  13D,  and is
filing this  schedule  because  of  Rule 13d-1(b)(3) or (4), check the following
box [ ].

<PAGE>
                                                             Page 2 of 37 pages.
================================================================================
CUSIP NO. 584699-10-2               SCHEDULE 13D
================================================================================
      1     NAME OF REPORTING PERSONS                                Investor AB

            S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
                                                                
================================================================================
      2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a)  [ ]
                                                                        (b)  [X]
================================================================================
      3     SEC USE ONLY
================================================================================
      4     SOURCE OF FUNDS*                                                  NA
================================================================================
      5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
            PURSUANT TO ITEM 2(d) or 2(e)                                    [ ]
================================================================================
      6     CITIZENSHIP OR PLACE OR ORGANIZATION               Kingdom of Sweden
================================================================================
  NUMBER OF SHARES          7     SOLE VOTING POWER                          [0]
 BENEFICIALLY OWNED
  BY EACH REPORTING         8     SHARED VOTING POWER                [1,619,000]
     PERSON WITH
                            9     SOLE DISPOSITIVE POWER                     [0]
                       
                           10     SHARED DISPOSITIVE POWER           [1,619,000]
================================================================================
      11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH 
            REPORTING PERSON                                         [1,619,000]
================================================================================
      12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*                                                  [ ]
================================================================================
      13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)            [6.2%]
================================================================================
      14    TYPE OF REPORTING PERSON*                                         CO
================================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
================================================================================

<PAGE>
                                                             Page 3 of 37 pages.
================================================================================
CUSIP NO. 584699-10-2               SCHEDULE 13D
================================================================================
      1     NAME OF REPORTING PERSONS        Investor International (U.S.), Inc.

            S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
                       
================================================================================
      2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*          (a)   [ ]
                                                                       (b)   [X]
================================================================================
      3     SEC USE ONLY
================================================================================
      4     SOURCE OF FUNDS*                                                  NA
================================================================================
      5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
            PURSUANT TO ITEM 2(d) or 2(e)                                    [ ]
================================================================================
      6     CITIZENSHIP OR PLACE OR ORGANIZATION               State of Delaware
================================================================================
  NUMBER OF SHARES           7     SOLE VOTING POWER                         [0]
 BENEFICIALLY OWNED                                            
  BY EACH REPORTING          8     SHARED VOTING POWER               [1,619,000]
     PERSON WITH                                               
                             9     SOLE DISPOSITIVE POWER                    [0]

                             10    SHARED DISPOSITIVE POWER          [1,619,000]
================================================================================
      11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH 
            REPORTING PERSON                                         [1,619,000]
================================================================================
      12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*                                                  [ ]
================================================================================
      13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)            [6.2%]
================================================================================
      14    TYPE OF REPORTING PERSON*                                         CO
================================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
================================================================================

<PAGE>
                                                             Page 4 of 37 pages.
================================================================================
CUSIP NO. 584699-10-2               SCHEDULE 13D
================================================================================
      1     NAME OF REPORTING PERSONS                    Investor Investments AB

            S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
                      
================================================================================
      2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a)  [ ]
                                                                        (b)  [X]
================================================================================
      3     SEC USE ONLY
================================================================================
      4     SOURCE OF FUNDS*                                                  OO
================================================================================
      5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
            PURSUANT TO ITEM 2(d) or 2(e)                                    [ ]
================================================================================
      6     CITIZENSHIP OR PLACE OR ORGANIZATION               Kingdom of Sweden
================================================================================
  NUMBER OF SHARES          7     SOLE VOTING POWER                          [0]
 BENEFICIALLY OWNED                                       
  BY EACH REPORTING         8     SHARED VOTING POWER                [1,619,000]
     PERSON WITH                                          
                            9     SOLE DISPOSITIVE POWER                     [0]
                            10    SHARED DISPOSITIVE POWER           [1,619,000]
================================================================================
      11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH 
            REPORTING PERSON                                         [1,619,000]
================================================================================
      12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*                                                  [ ]
================================================================================
      13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)            [6.2%]
================================================================================
      14    TYPE OF REPORTING PERSON*                                         CO
================================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
================================================================================

<PAGE>
                                                             Page 5 of 37 pages.
================================================================================
CUSIP NO. 584699-10-2               SCHEDULE 13D
================================================================================
      1     NAME OF REPORTING PERSONS                       Patricia Holdings AB

            S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
                        
================================================================================
      2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a)  [ ]
                                                                        (b)  [X]
================================================================================
      3     SEC USE ONLY
================================================================================
      4     SOURCE OF FUNDS*                                                  NA
================================================================================
      5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
            PURSUANT TO ITEM 2(d) or 2(e)                                    [ ]
================================================================================
      6     CITIZENSHIP OR PLACE OR ORGANIZATION               Kingdom of Sweden
================================================================================
  NUMBER OF SHARES         7     SOLE VOTING POWER                           [0]
 BENEFICIALLY OWNED                                      
  BY EACH REPORTING        8     SHARED VOTING POWER                 [1,619,000]
     PERSON WITH                                         
                           9     SOLE DISPOSITIVE POWER                      [0]

                           10    SHARED DISPOSITIVE POWER            [1,619,000]
================================================================================
      11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH 
            REPORTING PERSON                                         [1,619,000]
================================================================================
      12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*                                                  [ ]
================================================================================
      13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)            [6.2%]
================================================================================
      14    TYPE OF REPORTING PERSON*                                         CO
================================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
================================================================================

<PAGE>
                                                             Page 6 of 37 pages.
================================================================================
CUSIP NO. 584699-10-2               SCHEDULE 13D
================================================================================
      1     NAME OF REPORTING PERSONS                           Extoria Trade AB

            S.S. OR I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS
                       
================================================================================
      2     CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP*           (a)  [ ]
                                                                        (b)  [X]
================================================================================
      3     SEC USE ONLY
================================================================================
      4     SOURCE OF FUNDS*                                                  NA
================================================================================
      5     CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED
            PURSUANT TO ITEM 2(d) or 2(e)                                    [ ]
================================================================================
      6     CITIZENSHIP OR PLACE OR ORGANIZATION               Kingdom of Sweden
================================================================================
  NUMBER OF SHARES          7     SOLE VOTING POWER                          [0]
 BENEFICIALLY OWNED                                       
  BY EACH REPORTING         8     SHARED VOTING POWER                [1,619,000]
     PERSON WITH                                          
                            9     SOLE DISPOSITIVE POWER                     [0]

                            10    SHARED DISPOSITIVE POWER           [1,619,000]
================================================================================
      11    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH 
            REPORTING PERSON                                         [1,619,000]
================================================================================
      12    CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
            CERTAIN SHARES*                                                  [ ]
================================================================================
      13    PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)            [6.2%]
================================================================================
      14    TYPE OF REPORTING PERSON*                                         CO
================================================================================
                      *SEE INSTRUCTIONS BEFORE FILLING OUT!
================================================================================

<PAGE>
                                                             Page 7 of 37 pages.

CUSIP No.: 584699-10-2
                                  SCHEDULE 13D

Item 1.     Security and Issuer.

            This Schedule 13D relates to the shares of Common  Stock,  par value
$.01 per share (the "Common Stock"), of MedImmune,  Inc., a Delaware corporation
(the "Company").  The principal  executive offices of the Company are located at
35 West Watkins Mill Road, Gaithersburg, Maryland 20878.

Item 2.     Identity and Background.

            The names,  addresses and principal businesses of the persons filing
this Schedule 13D are as follows:

            Investor   International   (U.S.),   Inc.   ("IIUS"),   a   Delaware
            corporation,  whose address is 320 Park Avenue, New York, NY, 10022,
            and which is engaged in the  business of  investing  in publicly and
            non-publicly traded equity and debt instruments;

            Extoria Trade AB ("ETAB"), a Swedish  corporation,  whose address is
            S-103 32, Stockholm, Sweden, and which is engaged in the business of
            investing  in  publicly  and  non-publicly  traded  equity  and debt
            instruments;

            Investor  Investments  AB  ("IIAB")  a  Swedish  corporation,  whose
            address is S-103 32,  Stockholm,  Sweden and which is engaged in the
            business of long-term holding of equity securities;

            Patricia  Holdings AB  ("Patricia"),  a Swedish  corporation,  whose
            address is S-103 32,  Stockholm,  Sweden and which is engaged in the
            business of long-term holding of equity securities; and

            Investor AB ("Investor  AB"), a publicly-held  Swedish  corporation,
            whose address is S-103 32, Stockholm, Sweden and which is engaged in
            the business of the long-term holding of equity securities.

            All of the issued and  outstanding  common stock of IIUS is owned by
ETAB. All of the issued and  outstanding  common stock of ETAB is owned by IIAB.
All of the issued and outstanding common stock of IIAB is owned by Patricia. All
of the issued and outstanding  common stock of Patricia is owned by Investor AB.
For purposes of this statement, IIUS, ETAB, IIAB, Patricia and Investor AB shall
be referred to collectively as the "Filing Persons."


<PAGE>
                                                             Page 8 of 37 pages.


CUSIP No.: 584699-10-2

            Annex I attached  hereto and  incorporated  herein by reference sets
forth the  following  information  with respect to each  director and  executive
officer of the Filing Persons:  (a) name; (b) residence or business address; and
(c) present principal  occupation or employment and the name, principal business
and address of any corporation or other organization in which such employment is
conducted.  Except as otherwise  set forth in Annex I, all of the  directors and
executive  officers of the Filing Persons  identified in Annex I are citizens of
Sweden.

            None of the  Filing  Persons  or, to their  knowledge,  any  persons
listed on Annex I hereto, has, during the last five years, been (i) convicted in
a criminal proceeding  (excluding traffic violations or similar misdemeanors) or
(ii) a party to a civil  proceeding  of a  judicial  or  administrative  body of
competent  jurisdiction  as a result  of which  such  person  was  subject  to a
judgment,  decree or final order enjoining future  violations of, or prohibiting
or mandating  activities subject to, federal or state securities laws or finding
any violation with respect to such laws.

Item 3.     Source and Amount of Funds or Other Consideration.

            The shares of Common Stock reported in Item 5(a) (the "Shares") were
acquired  with  internally  generated  funds,  which  aggregated   approximately
$37,491,006 (exclusive of any expenses or commissions).

Item 4.     Purpose of the Transaction.

            The  Filing  Persons  purchased  the  Shares  from the  Company  for
investment purposes. Pursuant to the Subscription Agreement described in Item 6,
the Shares have been  registered for resale under the Securities Act of 1933, as
amended. Although their intention could change in the future, the Filing Persons
have no current intention to dispose of the Shares. In addition,  depending upon
their evaluation of the Company's business, operations and prospects, the market
price of the Common Stock,  and other future  developments,  the Filing  Persons
could acquire additional shares of Common Stock in the future.

            Except as set forth in this  response to Item 4, at the date of this
Schedule 13D none of the Filing  Persons has any plan or proposal  which relates
to or would  result in any of the actions  specified in clauses (a) through (j),
inclusive, of Item 4 of Schedule 13D.

<PAGE>
                                                             Page 9 of 37 pages.

CUSIP No.: 584699-10-2

Item 5.     Interest in Securities of the Issuer.

            (a) As of the close of business on January 21,  1998,  IIAB owned of
record and  beneficially an aggregate of 1,619,000 shares of Common Stock of the
Company,  representing approximately 6.2% of the outstanding Common Stock of the
Company.

            Under  Section  13(d) of the  Securities  Exchange  Act of 1934,  as
amended (the "Exchange  Act"),  and the rules and regulations  thereunder,  as a
result of the stock ownership relationships described in Item 2 of this Schedule
13D, Investor AB, Patricia,  ETAB and IIUS may be deemed to beneficially own the
1,619,000  shares of Common  Stock of the Company  owned by IIAB over which they
share, or may be deemed to share,  the power to dispose of and vote such shares.
However,  the filing of this Schedule 13D shall not be construed as an admission
that for the purposes of Section 13(d) of the Exchange  Act, or  otherwise,  the
Filing  Persons  are a "person" as defined by Section  13(d)(3) of the  Exchange
Act.

            (b) IIAB,  and  by  reason  of  the  stock  ownership  relationships
described in Item 2 of this Schedule 13D,  Investor AB, Patricia,  ETAB and IIUS
may be deemed to have shared power to vote or to direct the vote, and to dispose
or direct the disposition of, the Shares.

            (c) On January 21, 1998,  IIAB  purchased  500,000  shares of Common
Stock from the Company in a private  transaction for a purchase price of $39 per
share,  or an aggregate of  $19,500,000.  Except as otherwise  disclosed in this
Item 5(c), none of the Filing Persons or, to their knowledge, any of the persons
listed in Annex I, has  effected  any  transaction  in the  Common  Stock of the
Company during the sixty days prior to the date of this Schedule 13D.

            (d) To the best of their  knowledge,  none of the Filing Persons or,
to their  knowledge,  any of the  persons  listed in Annex I, knows of any other
person  that has any right to  receive  or the power to direct  the  receipt  of
dividends from, or the proceeds from the sale of, the Shares.

Item 6.     Contracts, Arrangements, Understandings or Relationship with
            Respect to Securities of the Issuer.

            In connection with the transaction  described in Item 5(c), IIAB and
the Company  entered into a Subscription  Agreement  dated January 12, 1998 (the
"Subscription Agreement") providing for the purchase of 500,000 shares of Common
Stock of the Company by IIAB.

<PAGE>
                                                            Page 10 of 37 pages.

CUSIP No.: 584699-10-2

ITEM 7.     Material to be Filed as Exhibits.

             (a) Power of Attorney of  Investor AB.

             (b) Power of Attorney of IIAB.

             (c) Power of Attorney of Patricia Holdings AB.

             (d) Power of Attorney of Extoria Trade AB.

             (e) Subscription  Agreement  dated  January 12, 1998,  between  the
                 Company and IIAB.



<PAGE>
                                                            Page 11 of 37 pages.

CUSIP No.: 584699-10-2

                                        SIGNATURES

            After reasonable inquiry and to the best of my knowledge and belief,
I certify that the information set forth in this statement is true, complete and
correct.

                                          Investor International (U.S.), Inc.

                                          By:  
                                             -------------------------------- 

                                          Name:  Fredrik Nilert
                                          Title:  Vice President

                                                as to each

                                          Investor Investments AB

                                          Investor AB

                                          Patricia Holdings AB

                                          Extoria Trade AB


                                          By:  
                                             -------------------------------- 
                                          Name:  Fredrik Nilert
                                          Title:  Attorney-in-Fact





<PAGE>
                                                            Page 12 of 37 pages.



CUSIP No.: 584699-10-2

                                  EXHIBIT INDEX



                                                            PAGE IN
                                                            SEQUENTIAL
EXHIBIT                                                     NUMBERING
  NO.                                                       SYSTEM
- --------                                                    -----------


 (a) Exhibit 1: Power of Attorney of Investor AB.

 (b) Exhibit 2: Power of Attorney of Investor 
     Investments AB.

 (c) Exhibit 3: Power of Attorney of Patricia
     Holdings AB.

 (d) Exhibit 4: Power of Attorney of Extoria 
     Trade AB.

 (e) Exhibit 5:  Subscription  Agreement,  dated  
     January 12, 1998,  between the   Company and IIAB.


<PAGE>
                                                            Page 13 of 37 pages.

CUSIP No.: 584699-10-2

                                     ANNEX I

     The  following is  a  list  of  the  executive  officers  and  directors of
Investor AB:

Name and Position:                        Present Principal Occupation
                                          and Business Address:

Percy Nils Barnevik                       Chairman of Investor AB 
(Chairman)                                S-103 32 Stockholm
                                          Sweden
                                         
Erik Jean Christian Belfrage              Investor AB
(Director)                                S-103 32 Stockholm
                                          Sweden
                                         
Bo Erik Gunnar Berggren                   Vice Chairman of Investor AB
(Director)                                Box 16100, S-103 32 Stockholm
                                          Sweden
                                         
Claes Ake Gustaf Dahlback                 President of Investor AB
(President and Managing Director)         S-103 32 Stockholm
                                          Sweden
                                              
Hakan Lars Mogren                         President and CEO of Investor AB
(President and Director)                  S-103 32 Stockholm
                                          Sweden
                                              
Mauritz Sahlin                            Chairman of Novare Kapital
(Director)                                S-103 32 Stockholm 
                                          Sweden
                                              
Johan Anders Fredrik Scharp               Vice Chairman of Investor AB
(Director)                                S-103 32 Stockholm
                                          Sweden

Peter D. Sutherland                       Chairman of Goldman 
(Director)                                Sachs International
                                          Donnybrook, 4 Dublin Eire
                                          Ireland

Nils Michael Aage Treschow                President and CEO of Electrolux AB
(Director)                                S-105 45 Stockholm
                                          Sweden


<PAGE>
                                                            Page 14 of 37 pages.


CUSIP No.: 584699-10-2


Marcus Wallenberg                         Executive Vice President of 
(Director)                                Investor AB
                                          S-103 32 Stockholm
                                          Sweden

(All of the above-named individuals are citizens of Sweden.)



      The following is a list of the executive officers and directors of IIAB:

Name and Position:                        Present Principal Occupation
                                          and Business Address:

Claes Ake Gustaf Dahlback                 President of Investor AB
(Director)                                S-103 32 Stockholm
                                          Sweden

Lars-Goran Vilhelm Gutberg                Investor AB
(Director)                                S-103 32 Stockholm
                                          Sweden

Guje Margareta Holmberg                   Investor AB
(Director)                                S-103 32 Stockholm
                                          Sweden

Marcus Wallenberg                         Executive Vice President of 
(Managing Director)                       Investor AB
                                          S-103 32 Stockholm
                                          Sweden

(All of the above-named individuals are citizens of Sweden.)


      The following is a list of the executive officers and directors of ETAB:

Name and Position:                       Present Principal Occupation
                                         and Business Address:

Claes Ake Gustaf Dahlback                President of Investor AB
(Director)                               S-103 32 Stockholm
                                         Sweden

Marcus Wallenberg                        Executive Vice President of Investor AB
(Director)                               S-103 32 Stockholm
                                         Sweden

<PAGE>
                                                            Page 15 of 37 pages.


CUSIP No.: 584699-10-2




Sven Olov Nyman                         Senior Vice President of Investor AB
(Managing Director)                     S-103 32 Stockholm
                                        Sweden

(All of the above-named individuals are citizens of Sweden.)



      The following is a list of the executive officers and directors of IIUS:

Name and Position:                      Present Principal Occupation
                                        and Business Address:


Sten Karlsson                           President of IIUS
(President)                             320 Park Avenue
                                        New York, NY 10022

Borje Ekholm                            Senior Vice President of Investor AB
(Director)                              10 Hill Street
                                        London W1X 7FU

Sven Olov Nyman                         Senior Vice President of Investor AB
(Director)                              S-103 32 Stockholm
                                        Sweden

Fredrik Nilert                          Vice President, Treasurer and Secretary
(Director)                              of IIUS, 320 Park Avenue
                                        New York, NY 10022

(All of the above-named individuals are citizens of Sweden. Frederik Nilert is a
citizen of the United States.)



     The following is a list of the executive officers and directors of Patricia
Holdings AB:

Name and Position:                     Present Principal Occupation
                                       and Business Address:


Claes Ake Gustaf Dahlback              President of Investor AB
(Director)                             S-103 32 Stockholm
                                       Sweden

<PAGE>
                                                            Page 16 of 37 pages.


CUSIP No.: 584699-10-2


Lars-Goran Vilhelm Gutberg             Investor AB
(Director)                             S-103 32 Stockholm
                                       Sweden

Guje Margareta Holmberg                Investor AB
(Director)                             S-103 32 Stockholm
                                       Sweden

Marcus Wallenberg                      Executive Vice President of Investor AB
(Managing Director)                    S-103 32 Stockholm
                                       Sweden

(All of the above-named individuals are citizens of Sweden.)


<PAGE>
                                                            Page 17 of 37 pages.




                                    EXHIBIT 1


                                POWER OF ATTORNEY





                              KNOW ALL MEN BY THESE  PRESENTS,  that INVESTOR AB
            constitutes  and  appoints  FREDRIK  NILERT,  its  true  and  lawful
            attorney-in-fact  and  agent,  with full power of  substitution  and
            resubstitution,  for it and in its name, place and stead, in any and
            all capacities,  to sign any and all Schedules  (including,  without
            limitation,   Schedules  13D),  Statements  and  Reports  which  the
            undersigned may be required to file with the Securities and Exchange
            Commission  pursuant to the Securities Exchange Act of 1934, and all
            amendments thereto, and to file the same, with all exhibits thereto,
            and other documents in connection therewith, with the Securities and
            Exchange Commission,  granting unto said  attorney-in-fact and agent
            full power and  authority  to do and perform  each and every act and
            thing  requisite and necessary to be done in and about the premises,
            as fully to all intents and  purposes  as the  undersigned  might or
            could do in person,  hereby  ratifying and  confirming all that said
            attorney-in-fact  and agent, or his substitutes,  may lawfully do or
            cause to be done by virtue hereof.



                                          INVESTOR AB



Dated:  January 29, 1998                        By:
                                                   -----------------------------


Dated:  January 29, 1998                        By:
                                                   -----------------------------


<PAGE>
                                                            Page 18 of 37 pages.



                                    EXHIBIT 2



                                POWER OF ATTORNEY





                              KNOW  ALL MEN BY  THESE  PRESENTS,  that  INVESTOR
            NVESTMENTS AB constitutes and appoints FREDRIK NILERT,  its true and
            lawful  attorney-in-fact  and agent, with full power of substitution
            and resubstitution,  for it and in its name, place and stead, in any
            and all  capacities,  to sign  any  and  all  Schedules  (including,
            without limitation, Schedules 13D), Statements and Reports which the
            undersigned may be required to file with the Securities and Exchange
            Commission  pursuant to the Securities Exchange Act of 1934, and all
            amendments thereto, and to file the same, with all exhibits thereto,
            and other documents in connection therewith, with the Securities and
            Exchange Commission,  granting unto said  attorney-in-fact and agent
            full power and  authority  to do and perform  each and every act and
            thing  requisite and necessary to be done in and about the premises,
            as fully to all intents and  purposes  as the  undersigned  might or
            could do in person,  hereby  ratifying and  confirming all that said
            attorney-in-fact  and agent, or his substitutes,  may lawfully do or
            cause to be done by virtue hereof.



                                          INVESTOR INVESTMENTS AB



Dated:  January 29, 1998                  By:
                                             -----------------------------



Dated:  January 29, 1998                  By: 
                                             -----------------------------  
<PAGE>
                                                            Page 19 of 37 pages.








                                    EXHIBIT 3



                                POWER OF ATTORNEY





                              KNOW  ALL MEN BY  THESE  PRESENTS,  that  PATRICIA
            HOLDINGS AB constitutes and appoints  FREDRIK  NILERT,  its true and
            lawful  attorney-in-fact  and agent, with full power of substitution
            and resubstitution,  for it and in its name, place and stead, in any
            and all  capacities,  to sign  any  and  all  Schedules  (including,
            without limitation, Schedules 13D), Statements and Reports which the
            undersigned may be required to file with the Securities and Exchange
            Commission  pursuant to the Securities Exchange Act of 1934, and all
            amendments thereto, and to file the same, with all exhibits thereto,
            and other documents in connection therewith, with the Securities and
            Exchange Commission,  granting unto said  attorney-in-fact and agent
            full power and  authority  to do and perform  each and every act and
            thing  requisite and necessary to be done in and about the premises,
            as fully to all intents and  purposes  as the  undersigned  might or
            could do in person,  hereby  ratifying and  confirming all that said
            attorney-in-fact  and agent, or his substitutes,  may lawfully do or
            cause to be done by virtue hereof.



                                          PATRICIA HOLDINGS AB



Dated:  January 29, 1998                  By:
                                             -----------------------------



Dated:  January 29, 1998                  By:
                                             -----------------------------


<PAGE>
                                                            Page 20 of 37 pages.





                                    EXHIBIT 4



                                POWER OF ATTORNEY





                              KNOW ALL MEN BY THESE PRESENTS, that EXTORIA TRADE
            AB  constitutes  and appoints  FREDRIK  NILERT,  its true and lawful
            attorney-in-fact  and  agent,  with full power of  substitution  and
            resubstitution,  for it and in its name, place and stead, in any and
            all capacities,  to sign any and all Schedules  (including,  without
            limitation,   Schedules  13D),  Statements  and  Reports  which  the
            undersigned may be required to file with the Securities and Exchange
            Commission  pursuant to the Securities Exchange Act of 1934, and all
            amendments thereto, and to file the same, with all exhibits thereto,
            and other documents in connection therewith, with the Securities and
            Exchange Commission,  granting unto said  attorney-in-fact and agent
            full power and  authority  to do and perform  each and every act and
            thing  requisite and necessary to be done in and about the premises,
            as fully to all intents and  purposes  as the  undersigned  might or
            could do in person,  hereby  ratifying and  confirming all that said
            attorney-in-fact  and agent, or his substitutes,  may lawfully do or
            cause to be done by virtue hereof.



                                          EXTORIA TRADE AB



Dated:  January 29, 1998                  By:
                                             -----------------------------



Dated:  January 29, 1998                  By:
                                             -----------------------------



<PAGE>
                                                            Page 21 of 37 pages.





                                    EXHIBIT 5

                               SUBSCRIPTION AGREEMENT


           THIS SUBSCRIPTION AGREEMENT (this "Agreement") is made as of the 12th
day of  January  1998,  between  MedImmune,  Inc.  (the  "Company"),  a Delaware
corporation   with  its  principal   offices  at  35  West  Watkins  Mill  Road,
Gaithersburg, MD 20878, and Investor Investments AB (the "Purchaser").

           IN CONSIDERATION of the mutual covenants contained in this Agreement,
the Company and the Purchaser agree as follows:

           SECTION 1. AUTHORIZATION OF SALE OF THE SHARES.  Subject to the terms
and conditions of this Agreement,  the Company has authorized the sale of shares
of the common stock, par value $.01 per share (the "Shares"), of the Company.

           SECTION 2. AGREEMENT TO SELL AND PURCHASE THE SHARES.  At the Closing
(as  defined in Section  3), the  Company  will sell to the  Purchaser,  and the
Purchaser will buy from the Company,  upon the terms and conditions  hereinafter
set forth, the number of Shares shown below at the purchase price indicated:

            NUMBER OF SHARES
                 TO BE
               PURCHASED      PRICE PER SHARE   AGGREGATE PRICE
               ---------      ---------------   ---------------
                500,000           $39.00          $19,500,000

           The  Company  proposes  to  enter  into  subscription  agreements  in
substantially  the same form as this Agreement with certain other investors (the
"Other  Purchasers")  and expects to complete  sales of the Shares to them.  The
Purchaser  and the  Other  Purchasers  are  hereinafter  sometimes  collectively
referred  to as the  "Purchasers,"  and  this  Agreement  and  the  subscription
agreements   executed  by  the  Other   Purchasers  are  hereinafter   sometimes
collectively referred to as the "Agreements."

           SECTION 3. DELIVERY OF THE SHARES AT THE CLOSING.  The  completion of
the  purchase  and sale of the Shares  (the  "Closing")  shall  occur as soon as
practicable  following the  effectiveness  of the  registration  statement to be
filed  by  the  Company  pursuant  to  Section  7.1  hereof  (the  "Registration
Statement")  at a place and time (the  "Closing  Date") to be  determined by the
Company and of which the Purchasers  will be notified by facsimile  transmission
or  otherwise.  At the  Closing,  the  Purchaser  shall pay to the  Company  the
purchase  Price for the Shares being  purchased  hereunder  by wire  transfer in
immediately  available  funds and the Company shall deliver to the Purchaser one
or more stock certificates  registered in the name of the Purchaser,  or in such
nominee  name(s) as  designated  by the  Purchaser,  representing  the number of
Shares set forth in Section 2 above. The name(s) in which the stock certificates
are to


<PAGE>
                                                            Page 22 of 37 pages.


be  registered  are set forth in the Stock  Certificate  Questionnaire  attached
hereto as part of Appendix I. The Company's  obligation to complete the purchase
and sale of the Shares an deliver such stock  certificate(s) to the Purchaser at
the Closing shall be subject to the following conditions, which may be waived by
the  Company:  (a)  receipt  by the  Company  by wire  transfer  of  immediately
available funds of the purchase price for the Shares being purchased  hereunder;
and (b) the accuracy of the representations and warranties made by the Purchaser
and the  fulfillment  of those  undertakings  of the  Purchaser  required  to be
fulfilled prior to the Closing. The Purchaser's obligation to accept delivery of
such stock  certificate(s)  and to pay for the Shares evidenced thereby shall be
subject to the following conditions: (a) the Registration Statement is effective
and was first declared  effective,  and the Purchaser received written notice of
such  effectiveness,  on or  prior to  March  30,  1998;  (b) the  shares  to be
purchased by the  Purchaser  under this  Agreement  shall have been approved for
quotation by the Nasdaq Stock  Market  ("NMS") on or before March 30, 1998;  and
(c) the accuracy in all material respects of the  representations and warranties
made by the Company herein and the fulfillment in all material respects of those
undertakings of the Company required to be fulfilled prior to Closing.

           SECTION 4.  REPRESENTATIONS,  WARRANTIES AND  COVENANTS.  The Company
hereby represents and warrants to, and covenants with, the Purchaser as follows:

           4.1.  ORGANIZATION  AND  QUALIFICATION.  The Company is a corporation
duly  organized,  validly  existing and in good  standing  under the laws of the
State of Delaware and has all requisite corporate power and authority to conduct
its business as currently  conducted.  The Company is duly  qualified  and is in
good  standing  as a  foreign  corporation  in each  jurisdiction  in which  the
character or location of its assets or  properties or the nature of its business
makes such  qualification  necessary,  except for such  jurisdictions  where the
failure to so qualify would not have a material  adverse effect on the business,
financial condition or results of operations of the Company.

           4.2.  AUTHORIZED CAPITAL STOCK. As of the date hereof, the authorized
capital stock of the Company consists of (a) 60,000,000  shares of common stock,
$.01 par value per share,  of which on January 9, 1998  24,461,415  shares  were
validly issued and outstanding, fully paid and non-assessable, and (b) 5,524,525
shares of undesignated  preferred stock, $.01 par value per share, none of which
are issued and outstanding.

           4.3. DUE EXECUTION,  DELIVERY AND PERFORMANCE OF THE AGREEMENTS.  The
Company's  execution,  delivery and  performance of this Agreement (a) have been
duly  authorized  under  Delaware law by all requisite  corporate  action by the
Company and (b) will not violate any law or the Certificate of  Incorporation or
By-laws of the Company or any  provision  of any material  indenture,  mortgage,
agreement  or other  material  instrument  to which the Company is a party or by
which the Company or its properties or assets is bound as of the date hereof, or
result in a breach of our  constitute  (upon  notice or lapse of time or both) a
default  under  any  such  indenture,  mortgage,  agreement  or  other  material
instrument  or result  in the  creation  or  imposition  of any  lien,  security
interest,  pledge  or other  encumbrance  upon any  properties  or assets of the
Company.  The Company has no  subsidiaries.  Upon the  execution and delivery of
this  Agreement  by the Company and assuming  the valid  execution  and delivery
hereof by the Purchaser,  this  Agreement will  constitute the valid and binding
obligation of the Company,  


<PAGE>
                                                            Page 23 of 37 pages.


enforceable  in  accordance  with its  terms,  except as  enforceability  may be
limited by  applicable  bankruptcy,  insolvency,  reorganization,  moratorium or
similar laws affecting  creditors' rights generally and except as enforceability
may be subject to  general  principles  of equity  (regardless  of whether  such
enforceability  is considered in a proceeding in equity or at law) and except as
the  indemnification  agreements  of the  Company i Section  7.3  hereof  may be
legally unenforceable.

           4.4. LISTING OF SHARES ON NMS. The Company shall use its best efforts
to maintain the listing of the Shares on the NMS.

           4.5. ISSUANCE,  SALE AND DELIVERY OF THE SHARES. When issued and paid
for, the Shares to be sold  hereunder by the Company will be validly  issued and
outstanding,  fully paid and non-assessable.  In connection with the offering of
Shares, the Company has entered into subscription agreements with the Purchasers
to sell 1,700,000 Shares (including the Shares to be sold to the Purchaser) at a
price of $39.00 per Share.

           4.6. SEC REPORTS AND FINANCIAL STATEMENTS.  The Company has furnished
to the Purchaser copies of the Company's Annual Report on Form 10-K for the year
ended  December 31, 1996,  Quarterly  Reports on Form 10-Q for the quarter ended
September  30, 1997 and its proxy  statement and certain other reports under the
Securities Exchange Act of 1934, as amended (the "Exchange Act")  (collectively,
the "SEC  Reports"),  each as filed with the Securities and Exchange  Commission
(the  "Commission"),  and the Company's 1996 Annual Report to Stockholders  (the
"1996  Annual  Report"),  which  reports  and proxy  statement  are  included as
exhibits  to  the  Private   Placement   Memorandum   (the  "Private   Placement
Memorandum"),  dated  January  9,  1998.  Each  SEC  Report  was in  substantial
compliance with the  requirements  of its respective  report form on the date of
filing,  and the SEC reports,  the 1996 Annual Report and the Private  Placement
Memorandum did not, on the date of filing or the date as of which information is
set forth  therein,  contain any untrue  statement of a material fact or omit to
state a material  fact  required to be stated  therein or  necessary to make the
statements  therein,  in the light of the  circumstances  under  which they were
made, not misleading.  The financial statements (including any related schedules
and/or  notes)  included in the SEC Reports and the 1996 Annual Report have been
prepared  in  accordance   with   generally   accepted   accounting   principles
consistently  applied  (except  as  may  be  indicated  in  the  notes  thereto)
throughout  the periods  involved  and fairly  present the  financial  position,
results  of  operations  and cash  flows  as of the  dates  and for the  periods
indicated therein.

           4.7.  INTELLECTUAL  PROPERTY.  Except  as  described  in the  Private
Placement  Memorandum  or in the SEC  Documents,  the Company  owns or possesses
sufficient  rights  to use all  material  patents,  patent  rights,  trademarks,
copyrights,  licenses,  inventions,  trade  secrets and  know-how  described  or
referred to in the SEC  Documents,  as owned or used by it or that are necessary
for the conduct of its  business as now  conducted  or as  described  in the SEC
Documents. Except as described in the SEC Documents, the Company has not entered
into or become party to any  material  development,  license or other  agreement
pursuant  to which it has  secured  the right or  obligation  to use, or granted
others the right or  obligation  to use,  any  trademarks,  servicemarks,  trade
names, copyrights, patents or any other intellectual property right.


<PAGE>
                                                            Page 24 of 37 pages.


           4.8. NO MATERIAL  CHANGE.  As of the date  hereof,  there has been no
material  adverse change in the financial  condition or results of operations of
the Company since  September 30, 1997.  From September 30, 1997 through the date
hereof  there has not  occurred any  material  adverse  change in the  Company's
business,  financial  condition or results of  operations  not  disclosed in the
Private Placement  Memorandum or the exhibits thereto, of a nature that would be
required in a registration  statement  filed under the Securities Act had such a
registration statement been filed by the Company on the date hereof.

           4.9. LEGAL OPINION.  Prior to closing,  Dewey Ballantine LLP, counsel
to the Company,  will deliver to the Purchasers a legal opinion substantially to
the effect that:

                  (i) The  Company  is a  corporation  duly  organized,  validly
      existing and in good standing  under the laws of the State of Delaware and
      has all requisite corporate power and authority to conduct its business as
      currently conducted;

                   (ii) As of the date of the opinion,  the  authorized  capital
      stock of the Company  consists of (a)  60,000,000  shares of common stock,
      $.01 par  value  per  share,  and (b)  5,524,525  shares  of  undesignated
      preferred stock, $.01 par value per share;

                   (iii) The Company's  execution,  delivery and  performance of
      this  Agreement (a) have been duly  authorized  under  Delaware law by all
      requisite  corporate  action by the  Company  and (b) will not violate any
      applicable  provision  of the  General  Corporation  Law of the  State  of
      Delaware or the Certificate of  Incorporation or By-laws of the Company or
      any  provision  of any  agreement,  contract  or  instrument  included  or
      incorporated by reference as an exhibit to the Company's  Annual Report on
      Form 10-K for the year ended  December 31,  1996,  or the  Company's  Form
      10-Q's and Form 8-K's  filed on or after  January 1, 1997,  or result in a
      breach of or  constitute a default under any such  agreement,  contract or
      instrument.

      Upon the  execution  and  delivery  of this  Agreement  by the Company and
      assuming the valid  execution and delivery  hereof by the Purchaser,  this
      Agreement will constitute the valid and binding obligation of the Company,
      enforceable in accordance with its terms,  except as enforceability may be
      limited by applicable bankruptcy, insolvency,  reorganization,  moratorium
      or  similar  laws  affecting  creditors'  rights  generally  and except as
      enforceability  may be subject to general principles of equity (regardless
      of whether such  enforceability is considered in a proceeding in equity or
      at law) and except that the  indemnification  agreements of the Company in
      Section 7.3 hereof may be legally unenforceable;

                   (iv)  When  issued  and  paid  for,  the  Shares  to be  sold
      hereunder  by  the  Company  will  be  validly  issued,   fully  paid  and
      non-assessable;

                   (v)  Such  counsel  has  been  advised  by the  staff  of the
      Securities   and  Exchange   Commission   (the   "Commission")   that  the
      Registration  Statement has become  effective  under the Securities Act of
      1933,  as amended (the  "Securities  Act"),  and, to the knowledge of such
      counsel,  no stop order  suspending the  effectiveness of the Registration



<PAGE>
                                                            Page 25 of 37 pages.


      Statement has been issued and no proceedings  for that purpose are pending
      before or contemplated by the Commission;

                   (vi)   The   Registration   Statement   and  the   prospectus
      constituting  a part thereof (the  "Prospectus")  and any  supplements  or
      amendments  thereto  (except for the  financial  statements  and the notes
      thereto  and the  schedules  and  other  financial  and  statistical  data
      included or  incorporated by reference  therein,  as to which such counsel
      need not express any opinion)  comply as to form in all material  respects
      with the requirements of the Securities Act; and

                  (vii) Assuming the accuracy of the Purchaser's representations
      and  warranties  under  Section 5  hereof,  the  issuance  and sale to the
      Purchaser of the Shares being  purchased  pursuant to this  Agreement  are
      exempt from the registration requirements of the Securities Act.

            In  addition,  such  counsel  shall  state  that  such  counsel  has
participated  in  conferences  with  officers and other  representatives  of the
Company at which  conferences  the contents of the  Registration  Statement  and
Prospectus and related matters were discussed and,  although such counsel is not
passing  upon  and  does  not  assume  any   responsibility  for  the  accuracy,
completeness  or  fairness  of the  statements  contained  in  the  Registration
Statement or the Prospectus (except as specified in the foregoing  opinion),  on
the basis of the foregoing,  no facts have come to the attention of such counsel
which lead such counsel to believe that the  Registration  Statement at the time
it became effective  (except with respect to the financial  statements and notes
and schedules  thereto and other  financial  data, as to which such counsel need
express no belief)  contained any untrue statement of a material fact or omitted
to state a material fact required to be stated  therein or necessary to make the
statements  therein  not  misleading,  or that  the  Prospectus  as  amended  or
supplemented  (except with  respect to the  financial  statements  and notes and
schedules  thereto and other  financial data, as to which such counsel need make
no statement) on the date thereof  contained any untrue  statement of a material
fact or  omitted  to  state a  material  fact  necessary  in  order  to make the
statements therein in the light of the circumstances under which they were made,
not misleading.

            SECTION  5.   REPRESENTATION,   WARRANTIES   AND  COVENANTS  OF  THE
PURCHASER. (a) The Purchaser represents and warrants to, and covenants with, the
Company that: (i) the Purchaser, taking into account the personnel and resources
it can bring to bear on the  purchase  of the  Shares  contemplated  hereby,  is
knowledgeable,  sophisticated  and  experienced  in making,  and is qualified to
make,  decisions with respect to investments in shares  presenting an investment
decision like that involved in the purchase of the Shares, including investments
in securities issued by companies  comparable to the Company, and has requested,
received, reviewed and considered all information it deems relevant in making an
informed  decision to purchase the Shares;  (ii) the  Purchaser is acquiring the
number of  Shares  set forth in  Section 2 above in the  ordinary  course of its
business  and for its own  account  for  investment  only  and  with no  present
intention of distributing any of such Shares or any arrangement or understanding
with any other persons  regarding  the  distribution  of such Shares;  (iii) the
Purchaser will not, directly or indirectly,  offer,  sell,  pledge,  transfer or
otherwise  dispose of (or  solicit  any  offers to buy,  purchase  or  otherwise
acquire  or take a pledge of) any of the Shares  except in  compliance  with the
Securities Act and


<PAGE>
                                                            Page 26 of 37 pages.

the  rules  and  regulations  promulgated  thereunder;  (iv) the  Purchaser  has
completed or caused to be completed the Registration Statement Questionnaire and
the Stock Certificate Questionnaire, both attached hereto as Appendix I, for use
in preparation of the Registration  Statement,  and the answers thereto are true
and  correct  as of the  date  hereof  and will be true  and  correct  as of the
effective  date  of the  Registration  Statement;  (v)  the  Purchaser  has,  in
connection  with its  decision  to  purchase  the  number of Shares set forth in
Section 2 above,  relied solely upon the Private  Placement  Memorandum  and the
exhibits thereto and the representations and warranties of the Company contained
herein;  and (vi) the Purchaser is a financial  institution that qualifies as an
"accredited investor" within the meaning of Rule 501 of Regulation D promulgated
under the Securities Act.

            (b) The Purchaser  hereby covenants with the Company not to make any
sale  of  the  Shares  without   effectively  causing  the  prospectus  delivery
requirements  under  the  Securities  Act to be  satisfied,  and  the  Purchaser
acknowledges  and agrees that such Shares are not  transferable  on the books of
the Company unless the  certificate  submitted to the transfer agent  evidencing
the Shares is accompanied by a separate officer's  certificate:  (i) in the form
of Appendix  II hereto;  (ii)  executed  by an officer  of, or other  authorized
person designated by, the Purchaser; and (iii) to the effect that (A) the Shares
have  been  sold in  accordance  with  the  Registration  Statement  and (B) the
requirement of delivering a current prospectus has been satisfied. The Purchaser
acknowledges  that there may occasionally be times when the Company must suspend
the use of the  Prospectus  until such time as an amendment to the  Registration
Statement  has  been  filed  by  the  Company  and  declared  effective  by  the
Commission,  or until such time as the Company has filed an  appropriate  report
with the  Commission  pursuant to the Exchange  Act,  which such report  becomes
incorporated by reference in the  Registration  Statement.  The Purchaser hereby
covenants that it will not sell any Shares pursuant to the Prospectus during the
period  commencing at the time at which the Company gives the Purchaser  written
notice of the suspension of the use of the Prospectus and ending at the time the
Company gives the Purchaser  notice that the  Purchaser  may  thereafter  effect
sales pursuant to the Prospectus;  provided, however, that the Company shall not
be entitled to suspend sales of Shares under the Registration Statement for more
than 60 days in any six-month period.

            (c) The Purchaser further  represents and warrants to, and covenants
with,  the Company that (i) the Purchaser has full right,  power,  authority and
capacity  to enter  into  this  Agreement  and to  consummate  the  transactions
contemplated  hereby  and has  taken  all  necessary  action  to  authorize  the
execution,  delivery  and  performance  of this  Agreement  and  (ii)  upon  the
execution and delivery of this  Agreement,  this  Agreement  shall  constitute a
valid and binding  obligation of the Purchaser,  enforceable in accordance  with
its terms,  except as  enforceability  may be limited by applicable  bankruptcy,
insolvency,  reorganization,  moratorium  or similar laws  affecting  creditors'
rights  generally  and  except  as  enforceability  may be  subject  to  general
principles of equity (regardless of whether such enforceability is considered in
a proceeding in equity or at law) and except as the  indemnification  agreements
of the Purchaser in Section 7.3 hereof may be legally unenforceable.

            SECTION 6. SURVIVAL OF  REPRESENTATIONS,  WARRANTIES AND Agreements.
Notwithstanding  any  investigation  made by any  party to this  Agreement,  all
covenants,  agreements,  representations  and warranties made by the Company and
the Purchaser herein and in 
<PAGE>
                                                            Page 27 of 37 pages.


the  certificates  for the Shares  delivered  pursuant  hereto shall survive the
execution of this  Agreement,  the delivery to the Purchaser of the Shares being
purchased and the payment therefor.

            SECTION 7.  REGISTRATION  OF  THE  SHARES;  COMPLIANCE  WITH  THE
SECURITIES ACT.

            7.1.  REGISTRATION PROCEDURES AND EXPENSES.  The Company shall:

             (a) as soon as practicable after the date hereof,  prepare and file
                 with the  Commission the  Registration  Statement on a Form S-3
                 for the sale of the Shares by the  Purchaser  from time to time
                 on the Nasdaq National Market or the facilities of any national
                 securities exchange on which the Company's common stock is then
                 traded  or  in  privately-negotiated  transactions;   provided,
                 however,  that in the event that at any time the filing of such
                 registration  statement on Form S-3 for purposes of registering
                 for resale the Shares,  the Company shall cause a  Registration
                 Statement on Form S-1 to be filed as soon as practicable.

             (b) use  its  best   efforts,   subject  to  receipt  of  necessary
                 information  from the  Purchasers,  to cause  the  Registration
                 Statement to become effective as soon as practicable;

             (c) prepare  and  file  with the  Commission  such  amendments  and
                 supplements  to the  Registration  Statement and the prospectus
                 used in  connection  therewith  as may be necessary to keep the
                 Registration Statement effective until all the Shares have been
                 sold pursuant thereto or until, by reason of Rule 144(k) of the
                 Commission  under  the  Securities  Act or any  other  rule  of
                 similar  effect,  the  Shares  held  by  non-affiliates  of the
                 Company are no longer  required to be  registered  for the sale
                 thereof by the Purchasers;

             (d) furnish to the Purchaser with respect to the shares  registered
                 under the Registration  Statement (and to each Underwriter,  if
                 any,  of  such  Shares  identified  in  writing  as such by the
                 Purchaser to the Company) such number of copies of prospectuses
                 and   preliminary   prospectuses   in   conformity   with   the
                 requirements  of the Securities Act and such other documents as
                 the Purchaser may  reasonably  request,  in order to facilitate
                 the  public  sale  or  other  disposition  of all or any of the
                 Shares by the Purchaser;

             (e) file  documents  required  of the  Company  for normal blue sky
                 clearance  in states  specified  in writing  by the  Purchaser;
                 PROVIDED,  HOWEVER,  that the Company  shall not be required to
                 qualify to do  business or consent to service of process in any
                 jurisdiction  in which it is not now so qualified or has not so
                 consented;

             (f) bear  all  expenses  in  connection   with  the  procedures  in
                 paragraphs  (a)  through  (e)  of  this  Section  7.1  and  the
                 registration  of  the  Shares  pursuant  to  

<PAGE>
                                                            Page 28 of 37 pages.


                 the  Registration  Statement,  other than fees and expenses, if
                 any,  of counsel or other  advisors to  the  Purchaser  or  the
                 Other Purchasers; and

             (g) if  requested  by the  Purchaser,  enter  into an  underwriting
                 agreement   contemplating   the   distribution  of  the  Shares
                 purchased  by the  Purchaser  through  an  underwritten  public
                 offering in such form,  scope and  substance as is customary in
                 underwritten offerings and cooperate with the Purchaser and the
                 underwriters in effecting such offering.

            The  Company  understands  that  the  Purchaser  disclaims  being an
"underwriter"  as defined in Section 2(11) of the  Securities  Act, but the fact
that the Purchaser may be deemed an underwriter shall not relieve the Company or
the Purchaser of any obligations it has hereunder.  A questionnaire  relating to
the  Registration  Statement to be completed by the Purchaser is attached hereto
as Appendix I.

            7.2.  TRANSFER OF SHARES AFTER  REGISTRATION.  The Purchaser  agrees
that it will not effect any  disposition  of the Shares or its right to purchase
the Shares that would constitute a sale within the meaning of the Securities Act
except (a) pursuant to the Registration  Statement referred to in Section 7.1 or
(b) pursuant to an exemption from the  registration  requirements  of applicable
securities  laws,  provided that in the case of a  transaction  pursuant to this
clause (b) the Purchaser  shall have first  delivered to the Company the written
opinion of counsel  reasonably  acceptable  to the Company and its counsel  that
such  transaction  may be effected under  applicable  securities laws other than
pursuant to the Registration Statement.  Notwithstanding the foregoing,  nothing
in this Agreement  shall prohibit the transfer  and/or  assignment of the Shares
owned by the Purchaser to another registered  investment company having the same
investment  advisor as the  Purchaser.  The Purchaser  will promptly  notify the
Company  of any  changes  in  the  information  set  forth  in the  Registration
Statement  regarding  the  Purchaser  or its resale  plans  described  under the
caption "Plan of Distribution."

            7.3.  INDEMNIFICATION.  For the purposes of this Section 7.3:

             (a) the term "Selling Shareholder" shall mean the Purchaser and any
                 officer, director,  employee, agent, affiliate or person deemed
                 to be in  control  of such  Purchaser  within  the  meaning  of
                 Section 15 of the  Securities Act or Section 20 of the Exchange
                 Act;

             (b) the term  "Registration  Statement" shall mean the Registration
                 Statement  referred  to in  Section  3  hereof  and  any  final
                 prospectus,  exhibit,  supplement  or amendment  included in or
                 relating to such Registration Statement; and

             (c) the term "untrue  statement" shall mean any untrue statement or
                 alleged  untrue  statement  of,  or  any  omission  or  alleged
                 omission to state, in the  Registration  Statement,  a material
                 fact  required to be stated  therein or  necessary  to make the
                 statements  therein,  in the light of the  circumstances  under
                 which they were made, not misleading.
<PAGE>
                                                            Page 29 of 37 pages.


            The Company  agrees to  indemnify  and hold  harmless  each  Selling
Shareholder from and against any losses, claims, damages or liabilities to which
such  Selling  Shareholder  may  become  subject  (under the  Securities  Act or
otherwise) insofar as such losses, claims, damages or liabilities (or actions or
proceedings in respect  thereof) arise out of, or are based upon, (i) any untrue
statement, or arise out of any failure by the Company to fulfill any undertaking
included in, the Registration  Statement,  the Private  Placement  Memorandum or
this Agreement,  or (ii) breach by the Company of any of its  representations or
warranties made or given in this Agreement,  and the Company will reimburse such
Selling  shareholder  as  incurred  for any legal or other  expenses  reasonably
incurred in  investigating,  defending  or  preparing to defend any such action,
proceeding or claim; PROVIDED,  HOWEVER, that the Company shall not be liable in
any such case to the extent that such loss,  claim,  damage or liability  arises
out of, or is based  upon,  (i) an untrue  statement  made in such  Registration
Statement in reliance upon and in conformity with written information  furnished
to the Company by or on behalf of such Selling Shareholder  specifically for use
in preparation  of the  Registration  Statement,  or the failure of such Selling
Shareholder  to comply with the covenants and  agreements  contained in Sections
5(b) or 7.2 hereof respecting sale of the Shares or any statement or omission in
any Prospectus that is corrected in any subsequent Prospectus that was delivered
to the Purchaser prior to the pertinent sale or sales by the Purchaser.

            The Purchaser agrees to indemnify and hold harmless the Company (and
each person,  if any, who controls the Company  within the meaning of Section 15
of the Securities  Act or section 20 of the Exchange  Act),  each officer of the
Company who signs the  Registration  Statement  and each director of the Company
from and against any losses, claims, damages or liabilities to which the Company
(or any such officer,  director or controlling person) may become subject (under
the  Securities Act or otherwise),  insofar as such losses,  claims,  damages or
liabilities (or actions or proceedings in respect  thereof) arise out of, or are
based upon, any failure to comply with the covenants and agreements contained in
Section  5(b)  or 7.2  hereof  respecting  sale  of the  Shares,  or any  untrue
statement of a material  fact  contained in the  Registration  Statement if such
untrue  statement  was made in  reliance  upon and in  conformity  with  written
information  furnished by or on behalf of the Purchaser  specifically for use in
preparation of the Registration Statement,  and the Purchaser will reimburse the
Company (or such officer,  director or controlling  person,  as the case may be)
for any legal or other expenses reasonably incurred in investigating, defending,
or preparing to defend any such action,  proceeding or claim;  provided that the
Purchaser's  indemnification  obligation is limited to the net proceeds received
from its sale of the Shares.

            If the indemnification provided for in this Section 7.3 is held by a
court of competent  jurisdiction to be unavailable to an indemnified  party with
respect to any loss,  liability,  claim,  damage, or expense referred to herein,
then the  indemnifying  party, in lieu of indemnifying  such  indemnified  party
hereunder,  shall  contribute to the amount paid or payable by such  indemnified
party as a result of such loss,  liability,  claim,  damage,  or expense in such
proportion as is appropriate  to reflect the relative fault of the  indemnifying
party on the one hand and of the  indemnified  party on the other in  connection
with the untrue  statement(s)  that  resulted  in such loss,  liability,  claim,
damage, or expense as well as any other relevant equitable  considerations.  The
relative fault of the indemnifying  party and of the indemnified  party shall be
determined by reference to, among other things,  whether the untrue statement(s)
relates to information  supplied 


<PAGE>
                                                            Page 30 of 37 pages.


                                                                                
by the indemnifying  party or by the indemnified party and the parties' relative
intent, knowledge, access to information,  and opportunity to correct or prevent
such untrue statement(s).

            The  obligations  of  the  Company  and  the  Purchaser  under  this
Agreement  shall  survive  the  completion  of  any  offering  of  Shares  in  a
registration statement under this Agreement, and otherwise.

            Promptly  after receipt by any  indemnified  person of a notice of a
claim or the  commencement  of any action in respect of which indemnity is to be
sought  against an  indemnifying  person  pursuant  to this  Section  7.3,  such
indemnified person shall notify the indemnifying person in writing of such claim
or  of  the  commencement  of  such  action,  and,  subject  to  the  provisions
hereinafter  stated,  such indemnifying  person shall be entitled to participate
therein,  and, to the extent it shall wish, to assume the defense thereof,  with
counsel reasonably  satisfactory to such indemnified  person.  After notice from
the indemnifying person to such indemnified person of its election to assume the
defense  thereof,   such  indemnifying  person  shall  not  be  liable  to  such
indemnified  person  for  any  legal  expenses  subsequently  incurred  by  such
indemnified  person in connection with the defense thereof;  PROVIDED,  HOWEVER,
that if there exists a conflict of interest that would make it inappropriate, in
the  opinion of  counsel  to the  indemnified  person,  for the same  counsel to
represent  both the  indemnified  person  and such  indemnifying  person  or any
officer, director,  employee, agent, affiliate or person deemed to be in control
of such  indemnifying  person  within the  meaning  of either  Section 15 of the
Securities Act or Section 20 of the Exchange Act, the  indemnified  person shall
be  entitled  to retain  its own  counsel at the  expense  of such  indemnifying
person.  It is understood,  however,  that the Company shall, in connection with
any one such action,  ,suit or proceeding or separate but substantially  similar
or related actions,  suits, or proceedings in the same jurisdiction  arising out
of the same general  allegations  or  circumstances  which have been joined,  be
liable  for the  reasonable  fees  and  expenses  of only one  separate  firm of
attorneys  (in  addition  to any  local  counsel)  at any time  for all  parties
entitled to indemnification  under the Agreements not having actual or potential
differing interests with the Company or among themselves.

            7.4.  TERMINATION  OF CONDITIONS  AND  OBLIGATIONS.  The  conditions
precedent imposed by Section 5 or this Section 7 upon the transferability of the
Shares shall cease and terminate as to any particular  number of the Shares when
such Shares shall have been effectively  registered under the Securities Act and
sold or  otherwise  disposed  of in  accordance  with  the  intended  method  of
disposition set forth in the Registration  Statement  covering such Shares or at
such time as an opinion of counsel  satisfactory  to the Company shall have been
rendered to the Purchaser to the effect that such  conditions  are not necessary
in order to comply with the Securities Act.

            7.5. INFORMATION AVAILABLE. So long as the Registration Statement is
effective covering the resale of Shares owned by the Purchaser, the Company will
furnish  to the  Purchaser  all  reports  required  by it to be filed  under the
Exchange Act and upon the reasonable  request of the Purchaser,  and an adequate
number of copies of the prospectuses to supply to any other party requiring such
prospectuses.

<PAGE>
                                                            Page 31 of 37 pages.


            SECTION 8. NO BROKERS.  Each of the parties hereto hereby represents
that,  on the basis of any  actions  and  agreements  by it,  there are no other
brokers or finders entitled to compensation from the Company or by the Purchaser
in connection with the sale of the Shares to the Purchaser.

            SECTION  9.  NOTICES.  All  notices,  requests,  consents  and other
communications  hereunder  shall be in writing,  shall be mailed by  first-class
registered or certified  airmail,  or nationally  recognized  overnight  express
courier,  postage or freight prepaid, and shall be deemed given to the following
addresses four business days after mailing if by registered or certified airmail
or one business day after deposit with an overnight express courier:

             (a)  if to the Company, to:

                  MedImmune, Inc.
                  35 West Watkins Mill Road
                  Gaithersburg, MD  20878
                  Attention:  chief Executive Officer

                  with a copy so mailed to:

                  Dewey Ballantine LLP
                  1301 Avenue of the Americas
                  New York, New York 10019
                  Attention:  Frederick W. Kanner

                or to such  other  person at such other  place as the  Company
               shall designate to the Purchaser in writing; and

             (b) if to the Purchaser,  at its address as set forth at the end of
                 this  Agreement,  or at such other  address or addresses as may
                 have been furnished to the Company in writing.

            SECTION  10.  CHANGES.  This  Agreement  may  not be  modified  or
amended except  pursuant to an instrument in writing signed by the Company and
the Purchaser.

            SECTION 11.  HEADINGS.  The  headings  of the various  sections of
this Agreement have been inserted for  convenience of reference only and shall
not be deemed to be part of this Agreement.

            SECTION 12.  SEVERABILITY.  In case any provision  contained in this
Agreement  should be  invalid,  illegal or  unenforceable  in any  respect,  the
validity,  legality and  enforceability  of the remaining  provisions  contained
herein shall not in any way be affected or impaired thereby.

            SECTION 13.  GOVERNING  LAW. This  Agreement  shall be governed by
and  construed  in  accordance  with the laws of the State of Delaware and the
federal law of the United States of America.
<PAGE>
                                                            Page 32 of 37 pages.


            SECTION 14.  COUNTERPARTS.  This Agreement may be executed in two or
more counterparts, each of which shall constitute an original, but all of which,
when taken  together,  shall  constitute  but one  instrument,  and shall become
effective when one or more counterparts have been signed by each party hereto an
delivered to the other parties.

            SECTION 15. EXPENSES.  Except as otherwise  specifically  provided
herein,  each  party  shall  bear its own  expenses  in  connection  with this
Agreement.

            SECTION  16.  PUBLICITY.  The  Purchaser  shall  not issue any press
releases or otherwise make any public statement with respect to the transactions
contemplated by this Agreement without the prior written consent of the Company,
except as may be required by applicable law or regulation.

            SECTION 17.  CONFIDENTIALITY.  The Purchaser acknowledges and agrees
that any  information  or data it has acquired  from the Company,  not otherwise
properly in the public domain, was received in confidence.  The Purchaser agrees
not to divulge, communicate or disclose, except as may be required by law or for
the performance of this Agreement, or use to the detriment of the Company or for
the  benefit  of any  other  person  or  persons,  or  misuse  in any  way,  any
confidential information of the Company.




<PAGE>
                                                            Page 33 of 37 pages.


                                                                      Appendix I


                                 MEDIMMUNE, INC.

                         STOCK CERTIFICATE QUESTIONNAIRE
                         -------------------------------

            Pursuant to Section 3 of the Subscription Agreement,  please provide
us with the following information:

1.   The exact name that your Shares
     are to be  registered  in (this
     is the name that will appear on
     your stock certificate(s)). You
     may  use  a  nominee   name  if
     appropriate:                                
                                                  ------------------------------

2.   The  relationship  between  the
     Purchaser of the Shares and the
     Registered   Holder  listed  in
     response to item 1 above:
                                                  ------------------------------


3.   The  mailing   address  of  the
     Registered   Holder  listed  in
     response to item 1 above:
                                                  ------------------------------

                                                  ------------------------------

                                                  ------------------------------

                                                  ------------------------------

4.   Tax  Identification  Number  of
     the Registered Holder listed in
     response to item 1 above:
                                                  ------------------------------



     Print or Type:
     
       Name of Purchaser:
                                                  ------------------------------

       Name of individual representing 
       Purchaser:
                                                  ------------------------------

       Title of individual representing a
       Purchaser:
                                                  ------------------------------

     Signature by:

        Individual representing Purchaser:
                                                  ------------------------------

<PAGE>
                                                            Page 34 of 37 pages.
                                                                      Appendix I


                                 MEDIMMUNE, INC.

                        REGISTRATION STATEMENT QUESTIONNAIRE
                        ------------------------------------

            In connection  with the preparation of the  Registration  Statement,
please provide us with the following information:


1.   Pursuant to the Selling Shareholder" section of the Registration Statement,
     please state your or your  organization's  name exactly as it should appear
     in the Registration Statement:

     ---------------------------------------------------------------------------


2. Please provide us with the following information as of January 12, 1998:

                                               
                                           Number of Shares, if any, which
   Number of Shares which are being         will be owned after completion
            included in the               of sale of Shares included in the
         Registration Statement                 Registration Statement


     ---------------------------------    --------------------------------------


3.   Have you or your  organization  had any position,  office or other material
     relationship   within  the  past  three  years  with  the  Company  or  its
     affiliates?

                         Yes                             No

                        -----                           -----

      If yes, please indicate the nature of any such relationships below:

      --------------------------------------------------------------------------

      --------------------------------------------------------------------------

      --------------------------------------------------------------------------


4.   Are you or is your organization  affiliated with any member of the National
     Association of Securities Dealers, Inc.?

                          Yes                                No

                         -----                              -----

      If yes, please indicate the nature of any such affiliation below:


      Print or Type:
     
        Name of Purchaser:
                                                  ------------------------------

        Name of individual representing 
        Purchaser:
                                                  ------------------------------

        Title of individual representing a
        Purchaser:
                                                  ------------------------------
<PAGE>
                                                            Page 35 of 37 pages.
                                                                      Appendix 1
 

     Signature by:

         Individual representing Purchaser:
                                                  ------------------------------


<PAGE>
                                                            Page 36 of 37 pages.
                                        

                   PURCHASER'S CERTIFICATE OF SUBSEQUENT SALE
                   ------------------------------------------


      The  undersigned,  [an officer of, or other  person  duly  authorized  by]

_________________  ________________________________________  [fill  in  official

name of institution]  hereby certifies that said institution is the Purchaser of

the shares evidenced by the attached certificate,  and as such, sold such shares

on   __________________   in  accordance  with  registration   statement  number

________________ [fill in Registration Number] and the requirement of delivering

a current prospectus has been complied with in connection with such sale.


      Print or Type:
     
        Name of Purchaser:
                                                  ------------------------------

        Name of individual representing 
        Purchaser:
                                                  ------------------------------

        Title of individual representing a
        Purchaser:
                                                  ------------------------------

            Individual representing Purchaser:


        Signature by:

            Individual representing Purchaser:
                                                  ------------------------------



<PAGE>
                                                            Page 37 of 37 pages.


                                                                      Appendix I


            IN WITNESS WHEREOF, the parties hereto have caused this Agreement to
be  executed  by their duly  authorized  representatives  as of the day and year
first above written.



                                         MEDIMMUNE, INC.





                                         By: 
                                            -------------------------------





                                         Name and address of Purchaser:


                                         ----------------------------------

                                         ----------------------------------

                                         ----------------------------------




                                         Signature of Authorized Representative:





                                         By:
                                             --------------------------------
                                             Name:

                                             Title:






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