MEDIMMUNE INC /DE
SC 13G/A, 1998-08-28
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                  SCHEDULE 13G

                    UNDER THE SECURITIES EXCHANGE ACT OF 1934

                               (AMENDMENT NO. 1)*

                                 MEDIMMUNE, INC.
- -------------------------------------------------------------------------------
                                (Name of Issuer)

                     COMMON STOCK, PAR VALUE $.01 PER SHARE
- -------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    584699102
                           --------------------------
                                  CUSIP Number)


- -------------------------------------------------------------------------------
              (Date of Event Which Requires Filing This Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed: 

     [ ] Rule 13d-1(b) 

     [X] Rule 13d-1(c) 

     [ ] Rule 13d-1(d)

   *The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed " for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see
the Notes).



<PAGE>   2



CUSIP No.   584699102

- -------------------------------------------------------------------------------

           1.    Names of Reporting Persons.

                 I.R.S. Identification Nos.  of above persons (entities only).

                 BB BIOTECH AG

- -------------------------------------------------------------------------------

           2.    Check the Appropriate Box if a Member of a Group (See 
                 Instructions)
                 (a)

                 (b)

- -------------------------------------------------------------------------------

           3.    SEC  Use Only

- -------------------------------------------------------------------------------

           4.    Citizenship or Place of Organization

                          SWITZERLAND
- -------------------------------------------------------------------------------

Number of               5.   Sole Voting Power
Shares Bene-   
ficially                                 -0-
Owned by Each  
Reporting               -------------------------------------------------------
Person With:   
                        6.   Shared Voting Power

                                         3,818,000

                        -------------------------------------------------------

                        7.   Sole Dispositive Power

                                         -0-
               
                        -------------------------------------------------------
               
                        8.   Shared Dispositive Power
               
                                         3,818,000

- -------------------------------------------------------------------------------

           9.   Aggregate Amount Beneficially Owned by Each Reporting Person

                               3,818,000

          10.   Check if the Aggregate Amount in Row (11) Excludes Certain 
                shares

          11.   Percent of Class Represented by amount in Row (11)
                               14.5%

- -------------------------------------------------------------------------------
          12.   Type of Reporting Person (See Instructions)            HC, CO

- -------------------------------------------------------------------------------




                                Page 2 of 6 pages


<PAGE>   3



CUSIP No.  584699102

- -------------------------------------------------------------------------------

           1.    Names of Reporting Persons.

                 I.R.S. Identification Nos.  of above persons (entities only).

                      BIOTECH FOCUS S.A.

- -------------------------------------------------------------------------------

           2.    Check the Appropriate Box if a Member of a Group 
                 (a) 
 
                 (b)

- -------------------------------------------------------------------------------

           3.    SEC  Use Only

- -------------------------------------------------------------------------------

           4.    Citizenship or Place of Organization

                         PANAMA

- -------------------------------------------------------------------------------

Number of               5.   Sole Voting Power
Shares Bene-  
ficially                                 -0-
Owned by Each 
Reporting               -------------------------------------------------------
Person With:  
                        6.   Shared Voting Power

                                         3,818,000

                        -------------------------------------------------------

                        7.   Sole Dispositive Power

                                         -0-


                        -------------------------------------------------------
 
                        8.   Shared Dispositive Power
                        
                                         3,818,000

- -------------------------------------------------------------------------------
           9.    Aggregate Amount Beneficially Owned by Each Reporting Person

                                3,818,000 

          10.    Check if the Aggregate Amount in Row (11) Excludes Certain 
                 shares

          11.    Percent of Class Represented by amount in Row (11) 
 
                                14.5%

- -------------------------------------------------------------------------------
          12.    Type of Reporting Person

                                CO

- -------------------------------------------------------------------------------



                                Page 3 of 6 pages


<PAGE>   4



CUSIP No.  584699102

- -------------------------------------------------------------------------------

           1.    Names of Reporting Persons.

                 I.R.S. Identification Nos.  of above persons (entities only).

                      BIOTECH TARGET S.A.

- -------------------------------------------------------------------------------

           2.    Check the Appropriate Box if a Member of a Group 
                 (a) 
 
                 (b)

- -------------------------------------------------------------------------------

           3.    SEC  Use Only

- -------------------------------------------------------------------------------

           4.    Citizenship or Place of Organization

                         PANAMA

- -------------------------------------------------------------------------------

Number of               5.   Sole Voting Power
Shares Bene-  
ficially                                 -0-
Owned by Each 
Reporting               -------------------------------------------------------
Person With:  
                        6.   Shared Voting Power

                                         -0-

                        -------------------------------------------------------

                        7.   Sole Dispositive Power

                                         -0-


                        -------------------------------------------------------
 
                        8.   Shared Dispositive Power
                        
                                         -0-

- -------------------------------------------------------------------------------
           9.    Aggregate Amount Beneficially Owned by Each Reporting Person

                                -0-

          10.    Check if the Aggregate Amount in Row (11) Excludes Certain 
                 shares

          11.    Percent of Class Represented by amount in Row (11) 
 
                                0%

- -------------------------------------------------------------------------------
          12.    Type of Reporting Person

                                CO

- -------------------------------------------------------------------------------



                                Page 4 of 6 pages


<PAGE>   5
                               EXPLANATORY NOTE

Biotech Target S.A. ("Biotech Target") is a wholly-owned subsidiary of BB
Biotech AG ("BB Biotech"). Therefore, BB Biotech may be deemed to be the
beneficial owner of the shares of common stock of MedImmune, Inc. directly
owned by Biotech Target. For internal purposes, on June 18, 1998 BB Biotech AG
caused Biotech Target to transfer all of its holdings of securities issued by
MedImmune, Inc. (consisting of the 3,818,000 shares of common stock of
MedImmune, Inc.) to another wholly-owned subsidiary of BB Biotech, Biotech
Focus S.A. ("Biotech Focus").  However, prior to the aforementioned transfer,
as well as after the transfer of shares from Biotech Target to Biotech Focus
was completed, BB Biotech was, and continues to be, the beneficial owner of the 
3,818,000 shares of common stock of MedImmune, Inc. which were previously
directly owned by Biotech Target, and which are now directly owned by Biotech
Focus.  The transfer to Biotech Focus involves no change in BB Biotech's
beneficial ownership of the 3,818,000 shares of common stock of MedImmune, Inc.
reported on this Schedule 13G.

ITEM 2.

     (a)   Name of Person Filing
                 BB Biotech AG
                 Biotech Focus S.A.
                 Biotech Target S.A.

     (b) Address of Principal Business Office or, if none, Residence

                 BB Biotech           Biotech Focus        Biotech Target    
                 Vordergasse 3        Swiss Bank Tower     Swiss Bank Tower  
                 8200 Schaffhausen    Panama 1             Panama 1          
                 CH/Switzerland       Republic of Panama   Republic of Panama

     (c)   Citizenship

                 See Item No. 4 of cover pages.

     (d)   Title of Class of Securities
                 Common Stock, Par Value $.01 Per Share

     (e)   CUSIP Number
                 584699102

ITEM 4.   OWNERSHIP

     Provide the following information regarding the aggregate number and 
percentage of the class of securities of the issuer identified in Item 1.

     (a)    Amount beneficially owned:
                 3,818,000

     (b)   Percent of class:
                   14.5%

     (c) Number of shares as to which the person has:

                 (i)   Sole power to vote or to direct the vote
                               -0-

                 (ii)  Shared power to vote or to direct the vote
                               3,818,000

                 (iii) Sole power to dispose or to direct the disposition of 
                               -0-

                 (iv)  Shared power to dispose or to direct the disposition of 
                               3,818,000

ITEM 7.   IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED 
          THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY

     This statement is filed jointly by BB Biotech, Biotech Focus and Biotech 
Target. Biotech Target and Biotech Focus are wholly-owned subsidiaries of BB
Biotech.


                                Page 5 of 6 pages


<PAGE>   6




                                   SIGNATURES

     After reasonable inquiry and the best of my knowledge and belief, I 
certify that the information set forth in this statement is true, complete and 
correct.

                                         BB BIOTECH AG

Date:   August 13, 1998                  By:   /s/ Hans-Joerg Graf
                                             ---------------------
                                         Name:  Hans-Joerg Graf
                                                ------------------
                                                Signatory Authority

Date:   August 13, 1998                  By:   /s/ Dr. Victor Bischoff
                                             -------------------------
                                         Name:  Dr. Victor Bischoff
                                                ------------------
                                                Vice Chairman and Director

                                         BIOTECH TARGET, S.A.

Date:   August 13, 1998                  By:  /s/ Dr. Andreas Bremer
                                             -----------------------
                                         Name:  Dr. Andreas Bremer
                                                ------------------
                                                Signatory Authority

Date:   August 13, 1998                  By:  /s/ Dr. Anders Hove
                                             --------------------
                                         Name:  Dr. Anders Hove
                                                ------------------
                                                Signatory Authority

                                Page 6 of 6 pages




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