PROTEON INC/MA
10-K405, 1998-03-31
COMPUTER COMMUNICATIONS EQUIPMENT
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<PAGE>   1
                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-K

                                   (MARK ONE)
               [ x ] ANNUAL REPORT TO SECTION 13 OR 15(d) OF THE
                 SECURITIES EXCHANGE ACT OF 1934 For the fiscal
                          year ended December 31, 1997
                                       OR
          [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
                        SECURITIES EXCHANGE ACT OF 1934
              For the transition period___________ to ____________.

                         Commission File Number 0-19175

                                  PROTEON, INC.
             (Exact name of registrant as specified in its charter)

          MASSACHUSETTS                             04-2531856
          -------------                             -----------           
(State or other jurisdiction of         (I.R.S. Employer Identification Number)
incorporation or organization)

NINE TECHNOLOGY DRIVE, WESTBOROUGH, MA                              01581
- --------------------------------------                              -----
(Address of principal executive offices)                         (Zip Code)

       Registrant's telephone number, including area code: (508) 898-2800
          Securities registered pursuant to Section 12(b) of the Act:
                                      None
          Securities registered pursuant to Section 12(g) of the Act:
                          COMMON STOCK, $.01 PAR VALUE
                          ----------------------------

    Indicate by check mark whether the Registrant (1) has filed all reports 
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
Registrant was required to file such report(s), and (2) has been subject to such
filing requirements for the past 90 days.

            YES        X                      NO

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405
of Regulation S-K is not contained herein, and will not be contained, to the
best of Registrant's knowledge, in definitive proxy or information statements
incorporated by reference in Part III of this Form 10-K or any amendment to this
Form 10-K. [X]

Aggregate market value of Registrant's voting stock held by non-affiliates of
the Registrant as of March 12, 1998; $16,252,911 (without admitting that any
person whose shares are not included in determining such value is an affiliate).

Indicate the number of shares outstanding of each of the Registrant's classes of
common stock as of the latest practicable date. Shares of Common Stock
outstanding as of March 12, 1998: 15,296,857.

DOCUMENTS INCORPORATED BY REFERENCE
Portions of the Registrant's Annual Report to Shareholders for the Company's
fiscal year ended December 31, 1997 (the "1997 Annual Report") are incorporated
by reference into Parts II and IV of this Report and portions of the
Registrant's Proxy Statement for its 1998 Annual Meeting of Shareholders to be
held on May 27, 1998 (the "1998 Proxy Statement") are incorporated by reference
into Part III of this Report. With the exception of those portions of the 1997
Annual Report and 1998 Proxy Statement expressly incorporated in this Report by
reference, such documents shall not be deemed filed as part of this Report.



<PAGE>   2
                                 
                                     PART I

                            ITEM 1. GENERAL BUSINESS

COMPANY OVERVIEW
- ----------------

Proteon, Inc. (together with its subsidiaries, including "OpenROUTE Networks, 
Inc.," "Proteon," or "the Company") is known worldwide as a pioneer in the
multi-billion dollar data communications industry. Proteon and its wholly owned
subsidiary, OpenROUTE Networks Inc., have distinguished themselves as leaders in
helping customers with network connectivity, and now, in particular, with
connectivity from what is commonly referred to as the network edge. For more
than 17 years, Proteon has shipped network connectivity products that have
helped customers grow and prosper through deploying network-centric computing.
Historically, Proteon local area networking (LAN) products have provided
connectivity solutions in more than 70 percent of the Fortune 100 companies.
Leveraging this expertise in mission-critical network solutions, Proteon has now
started to aggressively deliver this same quality of product and service for
Internet and Intranet connectivity. The Company is committed to providing
complete network access solutions that make networks more accessible, secure,
easier to use, manage, and operate. The Company's comprehensive line of network
access solutions includes products for Internet and Intranet access, and
supports small- to medium-sized enterprise businesses and large corporations
that outsource to network service providers.

The Company was incorporated in Massachusetts in January 1974 as Proteon
Associates, Inc. The Company changed its name to Proteon, Inc. in July 1983. Its
executive offices are located at Nine Technology Drive, Westborough,
Massachusetts, 01581, and its telephone number at that location is (508)
898-2800. The Company's testing and final-assembly facilities are located at the
same address. In January 1997, the Company announced the formation of a new
wholly owned subsidiary named OpenROUTE Networks, Inc. ("OpenROUTE Networks").
This new subsidiary was incorporated in the state of Delaware. Going forward,
the Company intends to focus its business on markets served by this new
subsidiary.

OpenROUTE Networks' markets encompass the fast growing Internet and Intranet
segments of the overall networking industry. For Internet and Intranet
connections, OpenROUTE Networks' products combine cost effectiveness with ease
of operation, interoperability, network security, reliability and performance.
The Company's customers include both the Global 1000 multinationals, as well as
those small to medium-sized enterprises requiring connections to the Internet
and to suppliers, customers, and business partners. Proteon, Inc.'s customers
encompass local area networking sites that implement the Token Ring network
topology.

During the second half of 1997, the Company aggressively redefined its business
strategy for its OpenROUTE Networks subsidiary. The new market opportunity for
OpenROUTE Networks can best be described as the connection of businesses and
institutions to public network services such as the Internet. The Company
believes that this market -- which is expected to be the focus of the Company's
energy throughout 1998 -- is just beginning to emerge. The Company believes
there are two main segments of this market. The first addresses the connecting
of a new generation of small- to medium-sized business users who do not have a
network today, but will use a public network service to extend their competitive
advantage and to transact business with each other. The Yankee Group, a leading
market research group based in Boston, Massachusetts, has estimated that on a
worldwide basis there are more than 10 million businesses with fewer than 500
employees. The second target is the outsourcing of networks from the traditional
corporate MIS manager to an outside provider such as MCI, Sprint, Worldcom,
PSINet, UUNet, or the Bell operating companies. Outsourcing allows the corporate
enterprise to focus on its core business, and not the operation of the network.
Corporations do not manage their own phone network, and the Company believes
that they are beginning to realize that their data networks can be viewed in the
same fashion. The Company believes that selling its customer premise equipment
to these major outsourcing providers is another powerful way to grow the
OpenROUTE Networks brand name.

                                                                            
                                      
<PAGE>   3


NETWORKING INDUSTRY

The data communications industry continues to undergo a fundamental shift away
from hierarchical single-vendor systems to open, peer-to-peer communications
networks and information management tools that provide users with greater
computing power and access to information. This evolution has fostered the
growth of two dynamic markets: workstations and networking. Workstations deliver
increasingly powerful, personal productivity tools, and data communications
networks provide the "highways" that distribute and share this processing power
throughout an organization. This enables users to more fully leverage and manage
information resources.

The peer-to-peer evolution has created an increased demand for client/server
based applications. The first impact of client/server based networks is the
increasing demand for inexpensive, easy to use, remote access routers. Remote
offices can now access corporate databases while running local application
programs. In addition, users are now gaining access to previously unreachable
resources including the Internet, corporate headquarters and other remote sites.
Any LAN-attached workstation with Internet Protocol (IP) client software can
send and receive electronic mail, access public databases worldwide, share files
and programs through File Transfer Protocol (FTP), participate in thousands of
business and consumer-related newsgroups, and easily browse the massive
quantities of information available on the World Wide Web. The Company believes
its OpenROUTE Networks products address the needs of this marketplace.

FORMATION OF NEW SUBSIDIARY

The formation of the new OpenROUTE Networks subsidiary is in keeping with the
Company's strengthened focus on the rapidly growing market for Internet and
Intranet connectivity. The Company defines Internet as a "public" network
accessible by all audiences, and the Intranet as a "private," secure network
with Internet-like characteristics that is most often used only by the employees
of a specific company or organization. OpenROUTE Networks is focusing on the
development, marketing and distribution of the Company's award-winning GT and
GTX Internet access router products and the new Dragon series of Internet
connectivity devices.

The new subsidiary was formed to bring together the Company's resources on the
GT family of high-performance, low-cost Internet Access routers and the ongoing
licensing of its OpenROUTE internetworking software suite. The name OpenROUTE
Networks is intended to reflect the Company's specific emphasis in the Internet
Access marketplace. In conjunction with the establishment of this new
subsidiary, the Company in 1997 also unveiled a new corporate logo. The new logo
is being used in a corporate branding campaign to better position GT and GTX
products in the market for Internet access connectivity, and Dragon products for
eventual sale at the retail level. The new name also reflects the "open" nature
of the public Internet. OpenROUTE Networks has a multi-faceted sales strategy to
meet the growing need to connect hundreds of thousands of organizations to the
Internet in a cost-effective and secure manner. A major OpenROUTE Networks sales
thrust is to focus on key and emerging product features for Internet Service
Providers (ISPs) and service providers which include ISPs, carriers and telcos
among their customers. PSINet, Inc., of Herndon, Virginia, one of the largest
independent ISPs in North America, has been a large customer of OpenROUTE
Networks for more than 18 months. Other significant ISP partners announced in
1997 included Ultranet Communications and IDT Corporation. The Company continues
to seek partnerships with other large ISPs.

                                                                              
<PAGE>   4


OpenROUTE Networks also markets products through OEM relationships. Digital
Equipment Corporation's Networking Division (now owned by Cabletron, Inc.) and
Nippon Telegraph and Telephone's (NTT) Advanced Technology Division currently
resell Proteon's GT Internet Access routers under their own brand names. A
business goal of OpenROUTE Networks is to announce other OEM relationships
during 1998. OpenROUTE Networks also sells Internet Access products through some
of the world's largest distributors such as Tech Data Corp. and Ingram Micro. In
addition, Value Added Resellers (VARs), including Racal Data Group, actively
market GT and GTX products in most domestic and international markets. OpenROUTE
Networks is targeting major sales in markets such as government, financial
services, health care, education, publishing, manufacturing, insurance,
professional services, libraries and entertainment through its service provider
partners.


SIGNIFICANT EXECUTIVE APPOINTMENTS AND CHANGES

During the second half of 1997, the Company initiated a program to significantly
strengthen its senior management staff. The Company believes this series of
appointments will enhance its position in the marketplace, allow for better 
management of the Company's financial operations, and further strengthen its 
sales and marketing operations.

The Company appointed Steven T. Shedd as Vice President, Finance, Chief
Financial Officer, Treasurer and Clerk in July 1997. Prior to joining Proteon,
Mr. Shedd served as the Vice President and Chief Financial Officer of Zoom
Telephonics since 1996. In 1995 Mr. Shedd was the Vice President and Chief
Financial Officer for Versyss, Inc. and from 1992 to 1995 Mr. Shedd served as
Vice President and Chief Financial Officer of TSI Corporation.

Mr. Eugene Y. Chang joined the Company as Vice President, Marketing in September
1997 from General DataComm Industries, Inc. where he had been serving as
Assistant Vice President for Systems and Architectures. From 1995 to early 1997,
Mr. Chang was Vice President for Strategic Business Development at Zoom
Telephonics. From 1985-1995, Mr. Chang served as Vice President of ISDN/Digital
Access Technologies at Microcom, Inc.

Mr. Robert A. Koch is presently Vice President, Engineering, Product Planning
and Management for the Company, a position he has held since October 1997. Mr.
Koch joined the Company in August 1993 as Product Marketing Director and held
that position until April 1997. From April 1997 until October 1997, Mr. Koch
served as Vice President of Product Planning for the Company.

In November 1997, Mr. Kenneth W. Hovaldt joined the Company as Vice President,
Sales for the Americas and Canada. From September 1996 to October 1997, Mr.
Hovaldt held the position of Vice President, Global Sales for Telco Systems.
From 1988 to 1996 Mr. Hovaldt served as Senior Vice President of Marketing,
Sales and Business Services for Fijitsu Network Switching of America, Inc.

Mr. Jack A. Ritter joined the Company in December 1997 as Vice President, Asia
Pacific Operations. Prior to joining Proteon, Mr. Ritter was the Director of
Marketing and Sales for the Southeast Asia Trade Alliance since 1995. From 1993
to 1995 Mr. Ritter held the position of Director of Independent Company Sales
for Fujitsu Networking Switching of America, Inc.
                                                                            
<PAGE>   5

LAN PRODUCTS AGREEMENT

In mid-1997, Proteon, Inc. and Microvitec PLC jointly announced the signing of
an agreement that provides for Microvitec to resell certain of Proteon's
products and obtain intellectual property rights for the Company's Ethernet LAN
products, manufacturing licenses, and access to other Proteon resources to
develop products and services for the LAN marketplace. Proteon LAN Products are
now being sold under the name "Proteon LAN Products by Microvitec," as well as
under the "Proteon" nameplate.

Microvitec PLC is a publicly listed information technology group based in
Bradford, UK, with 1997 annual revenues of approximately 55 million pounds ($91
million U.S.). The group has three divisions - Software, Networking and Displays
- - and operations in the UK, Germany, Canada and USA. The Network Division
includes companies that supply components to the major LAN equipment
manufacturers, manufacturers of Token Ring, Ethernet and wireless LAN products
and a large systems integrator.

COMMITMENT TO OPEN STANDARDS

Proteon and OpenROUTE Networks have always been committed to open,
standards-based product offerings. The Company believes that developing products
that offer multi-vendor interoperability achieved through leadership in, and
adherence to, open networking standards will continue to expand market
opportunities for many years to come. Proteon believes that the Company
contributes significant technical expertise to the development, promulgation and
adoption of key industry standards.

From a historical perspective, The Company co-authored both the Simple Network
Management Protocol (SNMP) network management standard and the Open Shortest
Path First (OSPF) internetwork routing standard. The Company has also developed
and shipped an extension to OSPF known as Multicast. Proteon continues to be an
active member of the OSPF Interoperability Group, an industry consortium formed
to ensure interoperability and further the acceptance of this important
standard. The Company has also continued to execute another high-level standards
activity as it has aggressively marketed its Data Link Switching (DLSw)
technology. DLSw technology, an industry standard, allows the Company's routers
to encapsulate Systems

                                                                            
<PAGE>   6

Network Architecture (SNA) traffic in IP, thus eliminating the need to have
separate backbone networks for SNA and LAN traffic. The implementation of DLSw
technology in its routing products continues to give the Company opportunities
in larger, headquarters site operations.

STRENGTHENING THE INTERNET ACCESS PRODUCT LINE

The Company continued to make progress during 1997 in introducing products for
the segments of the Internet Access marketplace that it believes are key to its
business strategy.

During 1997, the Company introduced two new major product lines. At the
Networld+Interop trade show in Atlanta, OpenROUTE Networks unveiled the GTX
1000, a new class of modular router that the Company believes leads the industry
in price/performance, network security, ease-of-use and management, and
investment protection. Designed and engineered to significantly reduce the cost
of investment in the essential networking equipment for Internet, Intranet and
Wide Area Networking (WAN) Connectivity, the GTX 1000 has a unique design that
puts the processing unit, memory, operating system software, and a built-in
Ethernet interface in the base unit. Depending on their individual needs, users
then select from a wide range of interface modules to be plugged into the three
configurable slots. This breakthrough design in a single box gives users the
flexibility to mix and match modules and add or change capabilities as their
needs change. The Company has applied for a U.S. Patent on the GTX 1000.

The GTX 1000 is also the first router in its class to ship with true Virtual
Private Network (VPN) functionality. VPNs, which are rapidly driving the global
acceptance of Internet commerce, connect sites within an organization's Intranet
over a public network such as the Internet. The VPN provides secure connections
via data encryption and authentication to guarantee the privacy of the
information as it passes over the public network. The GTX 1000 is priced
according to the modules selected. The product began shipping in December 1997.
When ordering, users can start with a single module and then add other
capabilities as their networks grow internally and expand geographically. The
GTX 1000 can support up to three "personality modules" including serial
interfaces with integrated CSU/DSU technology. ISDN modules are offered in four
variations (ISDN "U", ISDN "S/T", ISDN "U" with POTS, and ISDN "S/T" with POTS)
and are homologated for worldwide deployment. The GTX 1000 can also support up
to three modem modules, including support for 56K.

Toward the end of 1997, the Company introduced the Dragon(TM) series of
Internet Access devices. The two new Dragon products, which were formally
introduced before some 50,000 Internet World attendees in New York City, allow
small businesses to connect all their employees to the Internet through one
small unit. The base model Dragon features the ultimate in ease-of-use features
and the Company believes it is the best value on the market. The Dragon series
gives users the cost benefit of connecting their workgroup of PCs to the
Internet using a single shared Internet account via a shared modem and one
telephone line. Dragon users also have room to grow with an upgrade path to the
Dragon Pro. The Dragon Pro is ideal for the professional working at home or in a
small office. It features support for inbound calls; support for inbound
connections from the Internet; support for personal Web servers and other small
office servers; upgradability to dedicated high speed Internet links; and an
upgrade path to OpenROUTE Networks' GT Business Series product line. The base
model Dragon comes standard with a wide range of software features including
TCP/IP, asynchronous dial-up operation, PPP with PAP, CHAP, and compression. A
secure Internet connection is provided through Network Address Translation
(NAT). The Dragon Pro adds support for synchronous operation and other advanced
software features. Both Dragon products feature a 5-year limited warranty.
Dragon models, which began shipping in February 1998, are first available from
OpenROUTE Networks' Web site (http://www.openroute.com) and specialty catalogs.
The Company is also recruiting partners to sell Dragon products through the
retail channel.


                                                                             
<PAGE>   7

Also during the past year, the Company continued to expand its GT product line.
New products included: the GT 65 and GT 75, which provide support for the OSPF
protocol; the GTS 100 and GTS 205, more fully functional routers that now
include firewall support; the GT 255, a versatile wide area network
concentrator; and the GTSecure 250, a high performance LAN to LAN and LAN to WAN
firewall router for more complex network connections.

MAJOR EMPHASIS ON NETWORK SECURITY AND VIRTUAL PRIVATE NETWORKS

The Company has launched a major product marketing effort for network security
products. The program has been designed to address the networking marketplace's
need for affordable and secure ways of remotely accessing the Internet and
corporate Intranets. The Secure Internet/Intranet Program is offered to Internet
Service Providers (ISPs), telcos, carriers and end users, and is based on a
security hierarchy that recognizes the need for increasingly stronger security
mechanisms depending upon the type of user and the type of application. During
1997, OpenROUTE Networks addressed each of those levels of user/application with
strategic partnerships and products. Recent industry research indicates that in
a drive to achieve greater business success in the face of increasing global
competition, Internet and Intranet-based services hold the key for today's
virtual organization. Acting as a global backbone, these networks can link
branch offices, telecommuters, partners, suppliers or customers directly into
the business process.

The first product implementation of this program was the GTSecure-60 Firewall
Router, a high-performance, cost-effective solution that uniquely integrates
both full firewall and routing capabilities into a single product. The Company
believes that it was one of the first in the industry to offer this type of
integrated security product. Most other solutions call for users to manage
security in a separate server environment running expensive security software.
The Company believes that its low-cost approach provides adequate network
security for most small office users. Key features in the GTSecure-60 include a
dynamic firewall capability that restricts access from unauthorized users, a
sophisticated filtering system that opens only required ports while adapting to
changing network and user activity, and extensive authentication services via
industry-standard based RADIUS technology.

Later, the Company added the GTSecure-70 Firewall Router to its product line for
ISDN connections. In addition, the Company added IP filtering technology and
began active participation in testing with the National Computer Security
Association. The GTSecure Firewall Routers were subsequently certified by the
NCSA.

During the spring of 1997, OpenROUTE Networks, Inc. expanded the functionality
of its GT line of Internet Access products to include Sun Microsystems' Simple
Key Management for IP (SKIP) technology standard. Sun and OpenROUTE Networks
also announced plans for future joint sales and marketing activities. OpenROUTE
Networks' GTX and GT Business Series VPN solutions are interoperable with other
SKIP equipped network devices, including Sun's own SunScreen(TM) SPF and
SunScreen(TM) EFS Product lines, as well as the SunScreen(TM) SKIP client
software for Solaris and Windows '95 (also available from Sun). The Company
believes that customers who wish to communicate with their partners, customers
or employees using the scalability, ubiquity, and low costs of the Internet --
but demand industrial grade security -- now have a solution that scales from
client software, to the network infrastructure, on into the large scale Intranet
servers. The Company believes that the combination of Sun and OpenROUTE Networks
technology provides users with seamless, end-to-end network security for privacy
on the Internet today.

In the fall of 1997, OpenROUTE Networks continued to expand the functionality of
its product line by announcing expanded capabilities for its "ALLWays
Secure(TM)" network security portfolio. The Company believes that the "ALLWays
Secure" portfolio is the industry's broadest program for all-in-one, bulletproof
network security. With this new VPN capability, the Company believes OpenROUTE
Networks products now offer the most extensive levels of network security
including; stateful IP packet inspection, user authentication for Remote Access
users under the RADIUS protocol; and a dynamic Internal Firewall capability.

<PAGE>   8


INTERNETWORKING SOFTWARE LICENSING WITH OPENROUTE

OpenROUTE Networks' world class internetworking software suite -- known as
OpenROUTE -- is the foundation of the Company's high performance internetworking
solutions. All of OpenROUTE Networks' internetworking products ship with this
software technology. The Company has been developing this software suite for
approximately 12 years. In the later half of 1994, Proteon began licensing this
software. At that time, the Company completed two major internetworking software
licensing agreements. These agreements were reached with IBM and Digital
Equipment Corporation, two of the world's largest information technology
providers. The Company has also licensed its OpenROUTE software to Motorola's
Information Systems Group (ISG) and TELDAT, S.A., a leading European networking
products vendor headquartered in Madrid, Spain. In late 1997, the Company
announced that it had licensed a subset of OpenROUTE software to Ascend
Communications.

The Company believes that open routing software will be pervasive throughout
next generation networking technologies. OpenROUTE Network's charter is to
expand and manage the OpenROUTE software licensing business. This unit is
providing technology assessment, design feasibility and software porting
analysis for OpenROUTE licensees.

OPENROUTE DEVELOPMENT

The Company continues to invest research and development spending in its
OpenROUTE software. During the past year, the Company announced two new
OpenROUTE software upgrades. Early in the year, the Company released OpenROUTE
2.3 which included several new WAN capabilities that significantly enhance the
GT product line for ISDN links. Key new features included IP Address assignment,
support for callback, improved IP filters and support for IPXWAN, a new Novell
protocol that standardizes the transfer of IPX packets over various WAN media.
Later in the year, the Company announced Version 3.0 of OpenROUTE software. This
release featured support for OpenROUTE Addressing Services (OAS) which includes:
an extensive array of IP address management and configuration capabilities; a
number of Traffic Control Services (TCS) for better management of costly
connections and increased traffic associated with Internet and Intranet-based
networks; and enhanced ISDN with D-Channel Call-back, DOSBS and ISDN leased line
support.

BUSINESS PARTNERING WITH INTERNET SERVICE PROVIDERS

The Company continues to seek out business partnerships with Internet Service
Providers. The Company believes that Internet Service Providers offer a solid
path of wide-scale distribution for GT and GTX products. As ISPs have evolved
around the world, their equipment needs have paralleled this process. In many
cases where ISPs are connecting small businesses to the Internet or Intranet,
the installation of an Internet Access router is a necessity. By solidifying its
presence with ISPs on a global basis, the Company believes it can expand its
distribution and increase the potential to grow its business. The Company does
not currently have any agreements with ISPs that provide for the exclusive
installation of OpenROUTE Networks products. However, a major effort is being
made to work on development with ISPs, the goal of which is to ensure that
OpenROUTE Networks' products are the preferred choice. The Company's most
significant relationship continued to be with PSINet, Inc. of Herndon, Virginia.
Going forward, the Company's strategy is to increase the number of ISPs that
carry OpenROUTE Networks routers. The Company will also work with ISPs as they
support carriers and telcos who provide outsourced networking services for
corporations.




                                                                            
<PAGE>   9


COMPANY AWARDS AND HONORS

The Company continued to participate in industry-wide product testing and
evaluation and, as a result, has earned a number of recent honors. In the fall
of 1997, the Company won a "Tester's Choice" Award from Data Communications
magazine for the performance of its GlobeTrotter (GT) 72 and 75 ISDN routers. In
the September 1997 issue of ZD Internet magazine, the GT 72 was number one in a
data compression test that ranked 11 competitors. Earlier, Strategic Networks
Consulting, a leading market research firm, named the GT 70 the fastest overall
ISDN router in a major performance test among 10 leading vendors. The GT line
has also won a "Users' Choice" award from Communications News magazine. During
the first quarter of 1998, the Company's GTSecure 70 Firewall Router scored one
of the top two performance marks in an industry-wide test sponsored by Network
Computing magazine. The Company earned further recognition of its innovative
products when the GTX 1000 was voted a finalist in the Paris Networld+Interop
'97 Best of Show Awards for Best Internetworking Product.

LOCAL AREA NETWORKING PRODUCTS

The Company is continuing to market a number of Token Ring LAN products.
However, as mentioned earlier in this report, the Company is putting less
emphasis on LAN products than in previous years. The decision to partner with
Microvitec enhances the Company's ability to support current LAN customers and
future prospects. As the relationship with Microvitec ensues, Proteon will
continue to sell and service its brand name LAN products. Microvitec will
undertake its own sales and marketing efforts to market products under the
Proteon LAN Products by Microvitec brand name. In the future, Microvitec and
Proteon will share product development and engineering resources.

LOCAL ACCESS (TOKEN RING ADAPTERS)

Token Ring adapters provide the physical connectivity and Token Ring signaling
between the PC or workstation and the LAN cabling. Proteon markets the ProNET
family of Token Ring adapters. The family supports unshielded twisted pair (UTP)
and shielded twisted pair (STP) cabling options, the major PC platforms, and the
leading network operating systems.

The ProNET-4/16 Plus Series features models for all popular personal computer
bus types, including Industry Standard Architecture (ISA), Extended Industry
Standard Architecture (EISA), MicroChannel Architecture (MCA), Personal Computer
Memory Card International Association (PCMCIA), and Peripheral Component
Interconnect (PCI). The Company's newer model adapters are fully compatible with
the hundreds of thousands of earlier ProNET-4/16 models now operating in
production systems around the world.

The ProNET-4/16 family has demonstrated a Mean Time Between Failure (MTBF) of
more than 900,000 hours, or 200 years of continuous operation. All the Plus
Series adapters have a limited lifetime warranty, are designed with
state-of-the-art technology such as Surface Mounted Technology components, have
high levels of integration and are software configurable.

                                                                              
<PAGE>   10

Plus Series adapters also come with an assurance of interoperability. Proteon
offers a broad suite of certified compatible software drivers. Its RapiDrivers
are included as a standard feature inside leading network operating system
software such as Novell NetWare 4.0, Banyan VINES and Microsoft Windows NT.
Proteon's adapters have achieved interoperability certification with popular
third-party intelligent hub products in testing at the Token Ring
Interoperability Lab (TRIL) in Santa Clara, California.

Intelligent hubs are important elements for building structured and manageable
local area networks (LANs), since they provide connectivity and management of
the different cabling schemes and LAN topologies used throughout the network.
Proteon's Token Ring intelligent hubs and wire centers, which compete in the
workgroup network computing market, provide flexible and modular solutions to
cabling, as well as centralized physical network management and configuration.
The Company's Series 80 and Series 70 Intelligent Wire Center families provide
integrated support for 4/16 Mbps UTP, STP and fiber optic cabling, and are
appropriate for workgroups of up to 30 users.

The Company also markets the Series 75 Stackable Hub family, a portfolio of
standards-based, high-performance products that provides a cost effective
solution for building networked workgroups and extended workgroups and meeting
the demands for current and evolving client/server applications. The Series 75
Hub line is based on the p7500 base unit, a 16-port, self-managed active UTP
hub. The p7500 has a rear panel option slot for the addition of stack and SNMP
management modules, and modular ports for installation of trunk options such as
fiber optic links. The Series 75 architecture will support a stack of nine units
high, thus providing connectivity for up to 144 users.


MARKETING, SALES AND CUSTOMERS

End-users of the Company's products have typically been organizations with
critical applications requiring connectivity integrating their headquarters and
wide area computing environments. The Company's marketing and distribution
strategy is to reach these end-users primarily through an indirect sales channel
comprised of selected large systems integrators, Internet Service Providers,
original equipment manufacturers (OEMs), value added resellers (VARs),
telecommunications carriers, and distributors with experience in network
integration and a reputation for excellent service. As the Company moves
forward, it will be targeting a customer base that may not be familiar with
standard networking terms. The Company believes that this new generation of
users is mainly comprised of business executives who have used the Internet in
the home environment, and are now demanding this type of connectivity in the
workplace.

MARKETING PROGRAMS

The Company understands the critical nature of creating end-user awareness for
its products and capabilities. The Company's marketing programs in 1997 and
planned marketing programs for 1998 are focused on channel, telco, ISP, and
end-user awareness through: direct mail campaigns; targeted advertising;
significant educational and product announcement activities; public relations;
seminar programs; electronic advertising mediums such as the Internet; and
regional and large, national industry trade shows. These programs are intended
to enhance brand name recognition for the Company and its products with
end-users, generate sales leads for the Company's field sales force and the
Company's resellers, and support the sales efforts of its resellers. In the
future, the Company plans to devote more time and money to increasing  
recognition of OpenROUTE Networks brand name. In conjunction with the creation
of OpenROUTE Networks, the Company adopted a new, colorful logo that will play a
key role in the branding campaign. The Company plans to use some
consumer-oriented branding techniques to better drive sales. In 1998, the
Company also intends to launch new reseller programs and recruit more reseller
partners.



<PAGE>   11

Field Sales Force

The Company's field sales force is primarily responsible for providing sales
support and training to the Company's systems integrators, OEMs, ISPs, VARs,
telecommunications carriers, and distributors. In 1997, the Company focused a
portion of its sales force on direct presence at end-user sites with the goal of
providing awareness to the end-user of Proteon and OpenROUTE Networks' products
and the development of leads to support its reseller partners. The field sales
force has a number of offices in the United States, and international offices in
London, Singapore, Tokyo, Toronto, Paris, and Hong Kong. In late 1997, the
Company incurred expenses to add additional sales personnel in various parts of
the world. In a limited number of sales situations, the Company sells directly
to end user customers.

Systems Integrators and OEMs

Proteon and OpenROUTE Networks sell a large number of units through systems
integrators and OEMs. These organizations typically have technical expertise and
an installed customer base in either telecommunications or computer
communications, and are experienced in the sale and support of complex
networking solutions. In late 1997, and continuing into 1998, the Company
is attempting to increase its shipments through telecommunications providers
who install customer premise equipment. This trend is often referred to as
outsourcing.

VARs

The Company also sells its complete product line through Value Added Resellers
(VARs), which include Premier Access Partners and smaller regional VARs in
markets around the world. Many of these VARs are selected for their capability
to sell to and service small to medium-sized organizations, as well as for their
expertise in vertical industries or technologies. The Company's VARs also
include a number of large national and regional resellers. In late 1997, and
continuing into 1998, the Company has been de-emphasizing its reliance on VARs 
and concentrating more of its sales efforts through telecommunications carriers,
ISPs and other service providers.

Distributors

Proteon sells a substantial portion of its Token Ring adapter and intelligent
hub and wirecenter products in North America to a number of distributors, which
usually resell to resellers and dealers, including several national chains.
Typically, distributors market Proteon's Token Ring and intelligent hub products
to dealers, whereas VARs sell the complete product line, including routers, to
end-users. The Company's distributors include Ingram Micro and Tech Data.
Distributors also carry OpenROUTE Networks' internetworking products and service
the needs of VARs and other types of system integrators.

INTERNATIONAL SALES

The Company's products are currently marketed, sold and serviced internationally
by over 60 distributors, VARs, and OEMs. These resellers generally have
non-exclusive agreements applying to a countrywide territory. International
sales accounted for approximately 35.4% percent of net sales in 1997.

BACKLOG

Because of the generally short cycle between order and shipment (typically less
than 45 days) and occasional customer-initiated changes in delivery schedules,
the Company does not believe its backlog as of any particular date is
necessarily indicative of future sales levels.



                                                                            
<PAGE>   12

CUSTOMER SUPPORT AND SERVICE

The Company's customer service organization provides a comprehensive suite of
service and support programs for resellers and end-users. The underlying
philosophy of the Company is to provide end-users with alternatives for
acquiring services for their networking requirements. Users can contract
directly with the Company for service. Additionally, Proteon offers multiple
maintenance contract options designed to match the servicing capabilities and
needs of the customer. The service offerings consist of technical support
(remote and on-site), maintenance contracts, hardware and software upgrades,
product exchange, spares, depot repair, and professional services.

RESEARCH AND PRODUCT DEVELOPMENT

Management believes the Company's future success depends in large part upon
timely enhancement of existing products and the development of new products
that not only maintain technological excellence, but also improve the
capabilities, efficiency, and cost-effectiveness of the end-users' data
communications networks. The Company is developing new products to improve
price/performance ratios, enhance its network management capabilities, simplify
ease of use, enhance network security and ensure interoperability with other
vendors' standards-based products. The Company is also helping to define and
support emerging industry standards that underly the use of new technological
capabilities. The Company is currently participating in a variety of Internet
Engineering Task Force (IETF) working groups, and the IEEE 802.5 and 802.12
subcommittees.

In 1997, 1996, and 1995, the Company's research and product development
expenditures were $5,987,000, $9,353,000, and $8,802,000, respectively. All of
the Company's expenditures for hardware and software research and development
costs have been expensed as incurred.

MANUFACTURING

The Company's manufacturing operations primarily consist of systems level
integration and testing. The Company has developed a strategic relationship
with U.S. Assemblies, Taunton, Mass., a major subcontract manufacturer with
access to cost-effective, high volume manufacturing, distribution, and repair
capability worldwide. U.S. Assemblies manufactures the Company's board
assemblies for its router, hub, and adapter card product lines and specific,
turnkey manufacturing for a number of Proteon and OpenROUTE Networks products.
The Company believes that in the event of an interruption in manufacturing at
U.S. Assemblies, alternative subcontractors could be brought on line quickly.
U.S. Assemblies also operates a number of other facilities across the United
States. Proteon does some final assembly and testing of its intelligent hubs
and routers at its Westborough, Massachusetts manufacturing facility. A repair
depot and logistic operation is also located at Westborough, coordinating
global service requirements for all products. 

The Token Ring chipsets used in the Company's 4/16 Mbps adapters are currently
manufactured by Texas Instruments. The Company has an agreement with Texas
Instruments under which it believes it will be able to obtain adequate supplies
of these chipsets in a timely manner to meet customer demand. However, the
reduction or interruption in supply or a significant price increase could       
adversely affect the Company's operating results. The RISC processor presently
used in the Company's CNX 600 and CNX 500 bridging routers is available solely
from AMD. The Company believes, however, that other available RISC processors
could be substituted for the AMD chip, if necessary, with some product
modifications. Certain logic semiconductors, signal processors, and subassembly
components used in the Company's products are also available only from limited
sources. The Company has not experienced any significant problems in obtaining
required supplies of such limited source components and believes that
alternative sources could be developed quickly. However, such shortages could
result in production delays that might adversely affect the Company's business.
The Company's line of GTX and GT Business Series products incorporates
microprocessors supplied by Motorola. The Company is not aware of any shortages
of chips from Motorola, and believes that supplies will be adequate for the
coming year.



<PAGE>   13

Proteon continues to have OEM arrangements with manufacturers for some of its
Token Ring product offerings. The Company does not feel these arrangements
jeopardize the quality of the products the Company is shipping. In most cases,
if supply from one vendor was interrupted or made scarce, the Company could find
a comparable source for the affected product with limited delays in shipment.

COMPETITION

The data communications, networking and computer industries are highly
competitive and characterized by rapidly changing technology and evolving
industry standards. These advances result in frequent new product introductions,
increased capabilities and improvements in the relative price/performance of
networking products. The Company competes with several companies having greater
research and development, marketing and financial resources, manufacturing
capability, customer support organizations, and name recognition than those of
Proteon and OpenROUTE Networks.

Internet Access Market Competition

In its newer GTX and GT Business Series product lines, the Company manufactures
routers that connect users on the network edge. The Company believes that major
competitors in this market segment include Ascend Communications, Livingston
Systems, Netopia Systems, Cisco Systems, 3COM, Bay Networks, Xyplex, ACC, and
Ramp Networks, among others.

Local Area Networking Competition

IBM dominates the market for Token Ring network adapter card products. Other
significant competitors in the market for Token Ring adapter cards include Madge
Networks and Olicom. While Token Ring networking is an industry standard,
Proteon believes that its ability to successfully address the market for Token
Ring network products is dependent upon the compatibility and interoperability
of the Company's products with products offered by IBM and upon maintaining
compatibility with the Token Ring standard as it continues to evolve.

In addition, IBM is both the dominant supplier of Token Ring network products as
well as an established vendor of computer and networking systems and products at
most of the Company's existing and potential end user sites. As a result, the
Company believes that in order to address the market for Token Ring network
interface card products successfully, the Company's products and systems must
have more features, greater functionality, higher performance and/or lower price
than those offered by IBM. In the past, the Company believes it has been
successful in offering Token Ring network interface card products with better
features, functionality, performance and/or price than Token Ring products
offered by IBM.

INTELLECTUAL PROPERTY RIGHTS

The Company was granted a patent on February 18, 1992, for its Token Ring
synchronization technology, commonly referred to as JitterBuster. On July 21,
1992 the Company was granted a patent for Token Ring Equalizer. Each of these
patents has a life of 17 years from the date of grant. In September 1997 the
Company applied for a U.S. patent for its GTX modular Internet Access router.

Currently, Proteon relies principally upon a combination of contractual rights,
trade secrets, and copyright laws to establish and protect its proprietary
rights in its products. The Company believes that because of the rapid pace of
technological change in the data communications and computer industries, the
legal protection for its products is a less significant factor in the Company's
success than the knowledge, ability and experience of the Company's employees,
the frequency of product enhancements and the timeliness and quality of support
services provided by the Company.


                                                                             
<PAGE>   14

Certain technology used in the Company's products is licensed by the Company
from third parties, generally on a non-exclusive basis. These license agreements
generally require the Company to pay royalties (certain of these license
agreements include minimum royalty requirements) and to fulfill confidentiality
obligations in order to maintain the licenses. One of the Company's license
agreements is an exclusive license for a portion of the software incorporated in
the Company's bridging routers. In order to maintain the exclusivity of this
license, the Company must make minimum annual royalty or other payments in
addition to those required to maintain the license. The sum of these payments
for each year is relatively insignificant to the Company. The maximum royalties
payable under this license are limited in accordance with a formula. Generally,
if the Company does not pay minimum royalties or make other minimum payments
each year under this license, the license may be terminated. Absent a breach of
this license agreement by the Company, the license may be continued indefinitely
at the Company's option. The termination of this license would have a material
adverse effect on the Company's operations because the technology licensed under
this agreement is included in the software incorporated in the Company's
bridging router products, which provide a significant portion of the Company's
revenues.

RISK FACTORS

Technological Change, New Products and Industry Standards

The data communications industry continues to undergo a fundamental shift away
from hierarchical single vendor systems to open, peer-to-peer communications
networks and information management tools that provide users with greater
computing power and access to information. This evolution has fostered the
growth of two dynamic markets: workstations and networking. Workstations deliver
increasingly powerful, personal productivity tools, and data communications
networks provide the "highways" that distribute and share leverage and manage
information resource.

As the deployment of networks matures, four recent trends continue to develop:
networking of remote sites to the headquarters office via remote access
routers; reduction of network congestion with the implementation of local area
networks (LAN's); segmentation using various switching technologies; and the
push by businesses of all sizes and individuals to connection their systems and
networks to the Internet.

Proteon is positioning itself as a company focused on the network access
market. Proteon views the networks access market as having two segments -
Internet access and local access. Its current strategy is based upon
concentration on the Internet access market segment.

The market for the Company's products in characterized by rapidly changing
technology, new product introductions and multiplicity of current and evolving
industry standards. Accordingly, the Company believes that its future success
will depend on its continuing ability to enhance and expand its existing
products and to develop or private label other manufacturer's technology and
introduce in a timely fashion new products which incorporate new technologies,
conform to standards and achieve market acceptance.

There can be no assurance that the Company's strategy is the correct one under
the circumstances; that the Company has correctly assessed trends in the
marketplace; that the Company will be able to develop, market or support, or
secure external supplies of, such products successfully; or that the Company
will be able to respond effectively to technological changes, new product
announcements by others or new industry standards.

Manufacturing and Supply; Dependence on Suppliers

The Company's manufacturing operations primarily consist of assembly, testing
and quality control of materials, components, subassemblies, and systems. US
Assemblies, a major subcontract manufacturer with access to cost effective,
high volume manufacturing, distribution, and repair capability worldwide, and
other manufacture and majority of Proteon's board assemblies for its router,
hub, and adapter card product lines.

The Token Ring chipsets used in the Company's 4/16 Mbps and 4 Mbps adapters are
currently manufactured for external sale solely by Texas Instruments. The
Company has a agreement with Texas Instruments under which it believes it will
be able to obtain adequate suppliers of these chipsets in a timely manner to
meet customer demand.

Certain logic semiconductors, signal processors, and subassembly components
used in the Company's products are also available only from limited sources.
The Company has not experienced any significant problems in obtaining required
supplies of such limited source components and believes that alternative
sources could be developed quickly, in necessary.

Proteon continues to have OEm arrangement with manufacturers for some of its
Ethernet product offering. In most cases, if supplies from one vendor were
interrupted or reduced, the Company could find a comparable source for the
affected product with limited delays in shipment.

The inability to obtain sufficient sole or limited source components as
required, or to develop alternative sources if and as required in the future,
could result in delays or reductions in product shipments which would adversely
affect the Company's operation results. There can be no assurance that, in the
event of interruptions in contract manufacturing, supplies of components from
sole or limited sources or supplies of units from OEM vendors or similar
occurrences, the Company could find and engage suitable alternatives in a timely
manner. Such interruptions or the inability of Proteon to counteract them
successfully could have an adverse effect on the Company's business, operations
and finances.

Intellectual Property

Currently, Proteon relies principally upon a combination of contractual rights,
trade secrets, and copyright laws to establish and protect proprietary aspects
of its products. The Company believes that, because of the rapid pace of
technological change in the data communications and computer industries, legal
protection for its products is a less significant factor in the Company's
success than the knowledge, ability, and experience of the Company's employee,
the frequency of product enhancements and the timeliness and quality of support
services provided by the Company. However, should a successful challenge be
mounted against the rights of Proteon in and to its intellectual property, by
allegations of infringement on the rights of other or for any other reason, the
Company's business, operations and finances could be adversely affected.
Certain technology used in the Company's products is licensed by the Company
from third parties. The termination of certain of these license would have a
material adverse effect on the Company's operations.

PRODUCT COMPATIBILITY AND COMPETITION

Network Interface Card Products

The market for Token Ring network interface card products is dominated by IBM.
While Token Ring networking is an industry standard, Proteon believes that its
ability to address successfully the market for Token Ring network products is
dependent upon the compatibility and interoperability of the Company's products
with products offered by IBM and upon maintaining compatibility with the Token
Ring standard as it continues to evolve.

Internet Access (Routers)

Proteon expects to participate significantly in the market segment of internet
access routing specifically addressing the needs to users to connect to the
Internet of build corporate intranets The Company has enhanced its internet
access capabilities with the introduction of new products and expanded its
presence in the Integrated Services Digital Network (INDN) marketplace.

LAN Access

The Company continues to sell Token Ring Switches; intelligent hubs that
provide connectivity and management of different network cabling schemes and
LAN topologies; Ethernet hubs, the ProNET/E series, for the workgroup market
segment; Token Ring hubs, the Serial 75 Stackable Hub family for building
networked and extended workgroups; Token Ring adapters for physical
connectivity and Token Ring signaling between a PC or workstation and LAN
cabling; a muliport cards intended to provide a full range of solution for the
client/server marketplace. The Company also seeks opportunities to leverage
technology through licensing arrangements.

Internetworking Software

OpenROUTE(TM), Proteon's internetworking software suite, is the foundation of
the Company's high performance Internet access products. All of the Proteon's
internetworking products ship this software technology installed. Also, Proteon
licenses this software to other providers of internetworking products. 

As routing technology progresses, the Company may be required to modify its
routing and bridging software to maintain compatibility of its products with
various standards and interoperability with other manufacturers router
products. Failure by the Company to maintain such compatibility,
interoperability, and technical competencies could adversely affect the
Company's business, operations and finances.
<PAGE>   15
Competition

The data communications, networking and computer industries are highly
competitive and characterized by rapidly changing technology and evolving
industry standards. These advances result in frequent new product introductions,
increased capabilities and improvements in the relative price/performance of
networking products. As a competitor in the networking industry, Proteon
believes one of the keys to success will be making networks more accessible to a
broader base of customers. Proteon is committed to open, standards based
products, innovative solutions to customer requirements for reliable and high
performance networks, a favorable price/performance ratio, ease of installation
and ease of use.

The Company competes with several companies having greater research and
development, marketing and financial resources, manufacturing capability,
customer support organizations, and name recognition than those of the Company.
There can be no assurance that the Company will be able to compete successfully
in the future or that competitive pressures will not adversely affect the
Company's business.

Research and Product Development

Management believes the Company's future success depends in large part upon
timely enhancement of existing products and the development of new products
that not only maintain technological excellence, but also improve the
capabilities, efficiency, and cost effectiveness of the end users' data
communication networks. The Company is developing new products to improve
price/performance ratios, enhance its network management capabilities, simplify
ease of use, and ensure interoperability with other vendors' standards based
products.

Variability of Quarterly Operating Results

The Company's quarterly operating results may vary significantly depending upon
factors such as the timing of new product announcements and releases by the
Company and its competitors, the timing of significant orders, the mix of
products sold and the mix of distribution channels through which the products
are sold. In addition, substantially all of the Company's sales in each quarter
result from orders booked in that quarter. Consequently, if sales do not close
in any quarter as anticipated, the Company's results of operations for that
quarter would be adversely affected. Further, the Company's expense levels are
based, in part on its expectations of future sales. If sales levels are below
expectations, operating results may be adversely affected. Also, quarterly
results can be materially affected by the existence and/or the timing of
software licensing revenues.

Method of Distribution

The Company sells its products to end users worldwide primarily through an
indirect sales channel comprised of Internet Service Providers ("ISPs"),
Original Equipment Manufacturers ("OEMs"), Value Added Resellers ("VARs") and
distributor. These resellers also represent other lines of products which are,
in some cases, identical or complementary to, or which compete with, those of
the Company. While the Company attempts to encourage these resellers to focus
on its products through marketing and support programs, there is a risk that
these resellers may give higher priority to products of other suppliers,
thereby reducing their efforts devoted to selling the Company's products. One
reseller accounted for approximately 11%, 11% and 12%, of the Company's sales
in 1997, 1996 and 1995, respectively, and a second reseller accounted for
approximately 8%, 14% and 10% of the Company's sales in 1997, 1996, and 1995,
respectively.

There can be no assurance that the Company has selected appropriate channels
of distribution for its products or that existing resellers will dedicate
adequate resources to sales of the Company's products. Failure to do so could
result in an adverse impact on the Company's business, operations and finances.

Marketing, Sales and Customers

End users of Proteon's products have typically been organizations with critical
applications requiring connectivity integrating their headquarters and wide area
computing environments. Proteon's marketing and distribution strategy is to
reach these end users primarily through an indirect sales channel comprised of
ISPs, OEMs, VARs and distributors with experience in network integration and
reputation for excellent service. In addition, the Company's strategy includes
increased presence of Proteon's sales force in end user sites.

There can be no assurance that the Company has correctly formulated its end
user profile or selected appropriate methods of marketing and selling its
products. Failure to do so could result in an adverse impact on the Company's
business, operations and finances.

Liquidity

Failure of the Company to create and maintain adequate working capital and
liquidity, by sales of equity, obtaining lines of credit or otherwise, could
adversely impact the Company's business, operations and finances.

International Sales, Regulatory Standards and Currency Exchange

International sales accounted for 35.4%, 38.3% and 35.7% in 1997, 1996 and 1995
respectively, of the Company's net sales and the Company expects that
international sales will continue to be a significant portion of the Company's
business. Foreign regulatory bodies continue to establish standards different
from those in the United States, and the Company's products are designed
generally to meet those standards. The inability of the Company to design
products in compliance with such foreign standards could have an adverse effect
on the Company's operating results. The Company's international business may be
affected by changes in demand resulting from fluctuation in currency exchange
rates and tariffs and difficulties in obtaining export licenses.

Possible Volatility of Stock Price

The Company believes factors such as announcements of new products by the
Company or its competitors and quarterly variations in financial results could
cause the market price of the Common Stock to fluctuate substantially. In
addition, the stock market has experienced volatility which has particularly
affected the market prices for many high technology companies' stock and which
often has been unrelated to the operating performance of such companies. These
market fluctuations may adversely affect the price of the Company's Common
Stock.

Certain Charter and By Law Provisions

The Company's Amended and Restated Articles of Organization and By Laws contain
certain provisions that could have the effect of making it more difficult for
the third party to acquire, or of discouraging a third party from attempting to
acquire, control of the Company. Such provisions could limit the price that
certain investors might be willing to pay in the future for shares of the
Company's Common Stock. Certain of such provisions allow the Company to issue
preferred stock with rights senior to those of the Common Stock and impose
various procedural and other requirements which could make it more difficult
for stockholders to effect certain corporate actions.

YEAR 2000

The Company has given careful consideration to all systems and equipment, which
may be affected by the Year 2000 issue. Management is in the process of
developing an action plan that provides for the repair of replacement of all
systems with exposure to Year 2000 problems by the end of 1998, the cost of
which is not expected to have a material financial impact on the Company. The
plan calls for a combination of internal and external resources. The commitment
of internal resources is not expected to have a significant impact on the
Company's future sales and operating results.

EMPLOYEES

As of December 31, 1997, The Company employed a total of 127 persons, including
69 in sales, marketing and customer support, 27 in engineering and product
development, 13 in manufacturing, and 18 in finance and administration. None of
the Company's employees is represented by a labor union. The Company has
experienced no work stoppages and believes its employee relations are good.

REGISTERED TRADEMARKS

Proteon, OpenROUTE, TokenVIEW and ProNET are registered trademarks and
JitterBuster CNX 600, CNX 500, CNX 400, DNX 350, RapiDriver, OneVIEW, and
OverVIEW are trademarks of Proteon. Ethernet is a registered trademark and XNS
is a trademark of Xerox Corporation. IBM and NetView are registered trademarks
and SNA is a trademark of IBM. Motorola is a trademark of Motorola, Inc.; AMD is
a trademark of Advanced Micro Devices, Inc. AT&T is a trademark of AT&T.

                   
<PAGE>   16


                              ITEM 2.  PROPERTIES

The Company's principal administrative, marketing, manufacturing and product
development facilities are located in one building in Westborough, Massachusetts
and occupied a total of approximately 44,000 square feet as of December 31,
1997. The Company occupies these facilities under a lease agreement that expires
in April 2002. The Company has the option to extend the term of the lease of its
primary office and manufacturing facility for two five-year periods commencing
on May 1, 2002 and May 1, 2007. In addition, the Company leases nine sales and
support offices elsewhere in the United States and abroad. The Company believes
that its existing facilities are adequate for its current needs.

                           ITEM 3.  LEGAL PROCEEDINGS

Neither the Company nor any of its subsidiaries is a party to any material legal
proceedings nor is any property of the Company the subject of material legal 
proceedings.

          ITEM 4.  SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

No matters were submitted to a vote of stockholders during the fourth quarter of
the fiscal year ended December 31, 1997.


<PAGE>   17




                                     PART II

                     ITEM 5. MARKET FOR PROTEON COMMON STOCK
                         AND RELATED STOCKHOLDER MATTERS

         The section entitled "Stock Price History" in the 1997 Annual Report is
incorporated herein by reference.


                         ITEM 6. SELECTED FINANCIAL DATA

         The table entitled "Selected Consolidated Financial Data" contained in
the 1997 Annual Report is incorporated herein by reference. The table should be
read in conjunction with the consolidated financial statements and related notes
and other financial information appearing elsewhere in the 1997 Annual Report,
including Management's Discussion and Analysis of Financial Condition and
Results of Operations.


                         ITEM 7. MANAGEMENT'S DISCUSSION
                       AND ANALYSIS OF FINANCIAL CONDITION
                            AND RESULTS OF OPERATIONS

         The section entitled "Management's Discussion and Analysis of Financial
Condition and Results of Operations" contained in the 1997 Annual Report is
incorporated herein by reference.


               ITEM 7A. QUANTITATIVE AND QUALITATIVE DISCLOSURES
                               ABOUT MARKET RISK

         Not applicable.


               ITEM 8. FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

         The sections entitled "Consolidated Balance Sheets," "Consolidated
Statements of Operations," "Consolidated Statements of Stockholders' Equity,"
"Consolidated Statements of Cash Flows," "Notes to Consolidated Financial
Statements," "Quarterly Financial Data" and "Report of Independent Accountants"
contained in the 1997 Annual Report are incorporated herein by reference.


            ITEM 9. CHANGES IN AND DISAGREEMENTS WITH ACCOUNTANTS ON
                       ACCOUNTING AND FINANCIAL DISCLOSURE

         None.



<PAGE>   18



                                    PART III

                    ITEM 10. DIRECTORS AND EXECUTIVE OFFICERS
                                   OF PROTEON

         The sections entitled "Information About The Executive Officers,"
"Proposal 1: Election of Directors" and "Section 16(a) Beneficial Ownership
Reporting Compliance" contained in the Company's 1998 Proxy Statement which the
Company intends to file with the Securities and Exchange Commission on or about
April 8, 1998 are incorporated herein by reference.


                         ITEM 11. EXECUTIVE COMPENSATION

         The sections entitled "Compensation of Directors and Executive
Officers" contained in the 1998 Proxy Statement is incorporated herein by
reference.


                     ITEM 12. SECURITY OWNERSHIP OF CERTAIN
                        BENEFICIAL OWNERS AND MANAGEMENT

         The section entitled "Principal Shareholders" contained in the 1998
Proxy Statement is incorporated herein by reference.




<PAGE>   19


                                   PART IV

ITEM 14.  EXHIBITS, FINANCIAL STATEMENTS, SCHEDULE, AND REPORTS ON FORM 8-K

(a)      Financial Statements, Schedule, and Exhibits

         The financial statements, schedule, and exhibits listed below are filed
         as part of this Report:



1.   Financial statements:

         Consolidated Balance Sheets as of December 31, 1997 and 1996

         Consolidated Statements of Operations for the years ended December 31,
         1997, 1996 and 1995

         Consolidated Statements of Stockholders' Equity for the years ended
         December 31, 1997, 1996 and 1995

         Consolidated Statements of Cash Flows for the years ended
         December 31, 1997, 1996 and 1995

         Notes to Consolidated Financial Statements

         Report of Independent Accountants

2.  Schedule:

         II       Valuation and Qualifying Accounts

                  Schedules not listed above are omitted because of the absence 
                  of conditions under which they are required or because the
                  required information is included in the consolidated
                  financial statements or notes submitted.

                                                                             


<PAGE>   20


3.  Exhibits:

         Exhibit
         Number             Description

         (3.1)    Restated Articles of Organization as Amended 
         (3.3)    By-Laws, as amended and restated 
         (4.1)    Article 4 of the Restated Articles of Organization, (See
                  Exhibit 3.1)
         (4.2)    Form of Common Stock Certificate 
         (10.1)   Manufacturing Services Agreement, dated August 1, 1989 between
                  the Registrant and Texas Instruments, Inc.
         (10.2)   Purchase Agreement, dated August 1, 1989 between
                  the Registrant and Texas Instruments, Inc.
         (10.3)   Software License Agreement, dated January 1, 1990 between the
                  Registrant and Noel Chiappa
         (10.4)*  1991 Restated Stock Option Plan
         (10.5)*  1988 Nonqualified Stock Option Plan
         (10.6)*  Restated Employee Stock Award Plan
         (10.7)*  Consulting Agreement, dated August 31, 1989 between the
                  Registrant and David Clark
         (10.8)*  Form of Indemnification Agreement. An Indemnification
                  Agreement was entered into by and between the Registrant and
                  each of: Steven J. Bielagus, Daniel Capone, Jr., David Clark,
                  Howard C. Salwen, and certain other former Directors and
                  Executives. Although the agreements were executed on various
                  dates, each is the same as the Form of Indemnification
                  Agreements in all material respects and details, and therefore
                  the individual agreements are not filed herewith. 
         (10.9)*  Executive Compensation Arrangements Not Set Forth in Formal
                  Documents
         (10.10)* Consulting Agreement, dated August 25, 1993, between the
                  Registrant and Howard Salwen        
         (10.11)* Employment Agreement dated March 18, 1994, between the
                  Registrant and Steven J. Bielagus.
         (10.12)* Employment Agreement dated June 27, 1994 between the
                  Registrant and Daniel J. Capone, Jr.
         (10.13)  Lease Agreement dated December 19, 1994 between the Registrant
                  and WCB Twenty Limited Partnership.
         (10.14)* Severance Compensation Agreement dated March 11, 1996
                  between the Registrant and William T. Greer
         (10.15)* Employment Agreement dated October 16, 1996 between the
                  Registrant and Robert J. Connaughton, Jr.
         (10.16)* Severance Compensation Agreement dated October 21, 1996 
                  between the Registrant and Robert J. connaugton, Jr.
         (10.17)* Form of Severance Compensation Agreement. A Severance 
                  Compensation Agreement was entered into by and between the
                  Registrant and each of: Robert Koch, Steven T. Shedd, Richard
                  J. Arena, Eugene Y. Chang, Daniel Capone, Jr., Steven J.
                  Bielagus, Kenneth Holvaldt and Jack A. Ritter. Although the
                  agreements were executed on various dates, each is the same as
                  the Form of Severance Compensation Agreements in all material
                  respects and details, and therefore the individual agreements
                  are not filed herewith. 
         (10.18)  Amendment to Lease Agreement dated December 19, 1994 between
                  the Registrant and WCB Twenty Limited Partnership, dated May
                  23, 1997

<PAGE>   21
3. Exhibits (continued)

         Exhibit
         Number             Description

         (11)     Statement RE: Computation of Per Share Earnings
         (13)     The Annual Report to Stockholders of the Company for the
                  fiscal year ended December 31, 1997 (except for the pages and
                  information thereof expressly incorporated by reference in
                  this Form 10-K, the Annual Report to Shareholders is provided
                  solely for the information of the Securities and Exchange
                  Commission and is not deemed "filed" as part of this Form
                  10-K)
         (21)     Subsidiaries of the Registrant
         (23)     Consent of Coopers & Lybrand L.L.P.
         (27)     Financial Data Schedule

    *    Exhibit is a management contract or compensatory plan, contract or
         arrangement required to be filed as an Exhibit to this Form 10-K.

    (b)  Reports on Form 8-K
         The Company filed no reports on Form 8-K with the Securities and
         Exchange Commission during the last quarter of the fiscal year ended
         December 31, 1997.


<PAGE>   22



                                   SIGNATURES

Pursuant to the requirements of Section 13 or 15 (d) of the Securities Exchange
Act of 1934, Proteon, Inc. has duly caused this Annual Report on Form 10-K to be
signed on its behalf by the undersigned, thereunto duly authorized.


                            PROTEON, INC.
                            (Registrant)


March 25, 1998         By:/s/ Daniel J. Capone, Jr.
                       ------------------------------------
                       Daniel J. Capone, Jr.
                       President & Chief Executive Officer
                       (principal executive officer)


Pursuant to the requirements of the Securities Exchange Act of 1934, this report
has been signed below by the following persons on behalf of the Registrant and
in the capacities and on the dates indicated.


March 25, 1998         By:/s/ Daniel J. Capone, Jr.
                       ----------------------------
                       Daniel J. Capone, Jr.
                       President & Chief Executive 
                       Officer and Director

March 25, 1998         By:/s/ Steven T. Shedd
                       ----------------------
                       Steven T. Shedd
                       Vice President, Finance and Chief Financial Officer
                       Treasurer and Clerk
                       (principal financial officer)

March 25, 1998         By:/s/ James M. Roller
                       ----------------------
                       James M. Roller
                       Corporate Controller
                       (principal accounting officer)


March 25, 1998         By:/s/ David Clark
                       ----------------------
                       David Clark, Director


March 25, 1998         By:/s/ Robert M. Glorioso
                       -------------------------
                       Robert M. Glorioso, Director


March 25, 1998         By:/s/ Howard C. Salwen
                       -----------------------
                       Howard C. Salwen, Director




<PAGE>   23


REPORT OF INDEPENDENT ACCOUNTANTS

To the Board of Directors
and Stockholders of Proteon, Inc.:

Our report on the consolidated financial statements of Proteon, Inc. has been
incorporated by reference in the Form 10-K from the 1997 Annual Report to
Shareholders of Proteon, Inc. In connection with our audits of such financial
statements, we have also audited the related financial statement schedule
listed in item 14a(2) in this Form 10-K.

In our opinion, the financial statement schedule referred to above, when
considered in relation to the basic financial statements taken as a whole,
presents fairly, in all material respects, the information required to be
included therein.




                                            /s/  COOPERS & LYBRAND L.L.P.
                                            -----------------------------
Boston, Massachusetts
Date: February 11, 1998

                                                                             

<PAGE>   24



                                                                    SCHEDULE II
                                  PROTEON, INC.
                        VALUATION AND QUALIFYING ACCOUNTS
<TABLE>
<CAPTION>



                                 Balance at                   Uncollectible  Balance at
   Allowance for                 Beginning   Provision        Accounts          End of
Doubtful Accounts                of Period   for Bad Debt     Written Off       Period
- ---------------------------------------------------------------------------------------
<S>                               <C>         <C>             <C>              <C>     

Year ended December 31, 1997      $671,755    $438,773       ($183,920)        $926,608
                                                                                       
Year ended December 31, 1996       889,276      -             (217,521)         671,755

Year ended December 31, 1995       887,524      -                1,752          889,276


</TABLE>


<PAGE>   25



EXHIBIT INDEX


Exhibit
Number                              Description

(3.1)    Restated Articles of Organization as Amended*(c) (filed as Exhibit 3.1)
(3.3)    By-Laws, as amended and restated, of the Registrant * (a) (filed as
         Exhibit 3.3) 
(4.1)    Article 4 of the Restated Articles of Organization, (See Exhibit 3.1) 
(4.2)    Form of Common Stock Certificate * (b) (filed as Exhibit 4.2) 
(10.1)   Manufacturing Services Agreement, dated August 1, 1989 between the
         Registrant and Texas Instruments, Inc. * (a) (filed as Exhibit 10.3) 
(10.2)   Purchase Agreement, dated December 1, 1990 between the Registrant and
         Texas Instruments, Inc. * (a) (filed as Exhibit 10.4) 
(10.3)   Software License Agreement, dated January 1, 1990 between the
         Registrant and Noel Chiappa * (a) (filed as Exhibit 10.5)(+) 
(10.4)   1991 Restated Stock Option Plan * (d) (filed as Exhibit 19.1) 
(10.5)   1988 Nonqualified Stock Option Plan * (a) (filed as Exhibit 10.7) 
(10.6)   Restated Employee Stock Award Plan * (a) (filed as Exhibit 10.8) 
(10.7)   Consulting Agreement, dated August 31, 1989 between the Registrant and
         David Clark * (a) (filed as Exhibit 10.11) 
(10.8)   Form of Indemnification Agreement. An Indemnification Agreement was
         entered into by and between the Registrant and each of: David Allen,
         Steven J. Bielagus, Daniel Capone, Jr., David Clark, Howard C. Salwen,
         and certain other former Directors and Executives. Although the
         agreements were executed on various dates, each is the same as the Form
         of Indemnification Agreements in all material respects and details, and
         therefore the individual agreements are not filed herewith. * (a)
         (filed as Exhibit 10.17) 
(10.9)   Executive Compensation Arrangement Not Set Forth in Formal Document*
         (e) (filed as Exhibit 10.26) 
(10.10)  Consulting Agreement, dated August 25, 1993, between the Registrant and
         Howard Salwen * (f) (filed as Exhibit 10.1) 
(10.11)  Employment Agreement, dated March 18, 1994, between the Registrant and
         Steven J. Bielagus * (g) (filed as Exhibit 10.3) 
(10.12)  Employment Agreement, dated June 27, 1994 between the Registrant and
         Daniel J. Capone, Jr. * (h) (filed as Exhibit 10.4) 
(10.13)  Lease Agreement dated December 19, 1994 between the Registrant and WCB
         Twenty Limited Partnership * (i) (filed as Exhibit 10.31) 
(10.14)  Severance Compensation Agreement dated March 11, 1996 between the
         Registrant and William T. Greer * (j) (filed as Exhibit 10.28) 
(10.15)  Employment Agreement, dated October 16, 1996 between the Registrant and
         Robert J. Connaughton, Jr. * (j) (filed as Exhibit 10.29) 
(10.16)  Severance Compensation Agreement dated October 21, 1996 between the
         Registrant and Robert J. Connaughton, Jr. * (j) (filed as Exhibit
         10.30) 
(10.17)  Form of Severance Compensation Agreement. A Severance Compensation
         Agreement was entered into by and between the Registrant and each of:
         Robert Koch, Steven T. Shedd, Richard J. Arena, Eugene Y. Chang, Daniel
         J. Capone, Jr., Steven J. Bielagus, Kenneth Holvaldt and Jack A.
         Ritter. Although the agreements were executed on various dates, each is
         the same as the Form of Severance Compensation Agreements in all
         material respects and details, and therefore the individual agreements
         are not filed herewith. 
(10.18)  Amendment to Lease Agreement dated December 19, 1994 between Registrant
         and WCB Twenty Limited Partnership, dated May 23, 1997
<PAGE>   26
EXHIBIT INDEX (continued)

Exhibit
Number             Description

(11)     Statement RE: Computation of Per Share Earnings
(13)     The Annual Report to Stockholders of the Company for the fiscal year
         ended December 31, 1997 (except for the pages and information thereof
         expressly incorporated by reference in this Form 10-K, the Annual
         Report to Shareholders is provided solely for the information of the
         Securities and Exchange Commission and is not deemed "filed" as part of
         this Form 10-K)
(21)     Subsidiaries of the Registrant
(23)     Consent of Coopers & Lybrand L.L.P.
(27)     Financial Data Schedule


         All exhibit descriptions followed by an asterisk and a letter in
         parentheses were previously filed with the Securities and Exchange
         Commission as Exhibits to, and are hereby incorporated by reference
         from, the following documents:
         (a)     Registrant's Registration Statement on Form S-1 Registration
                 No. 33-40073.
         (b)     Amendment No. 1 on Form 8 to the Registrant's Registration
                 Statement on Form 8-A, File No. 0-19175.
         (c)     Registrant's Annual Report on Form 10-K for the fiscal year
                 ended December 31, 1991.
         (d)     Registrant's Quarterly Report on Form 10-Q for the quarter
                 ended June 27, 1992.
         (e)     Registrant's Annual Report on Form 10-K for the fiscal year
                 ended December 31, 1992.
         (f)     Registrant's Quarterly Report on Form 10-Q for the quarter
                 ended October 2, 1993.
         (g)     Registrant's Quarterly Report on Form 10-Q for the quarter
                 ended April 2, 1994.
         (h)     Registrant's Quarterly Report on Form 10-Q for the quarter
                 ended July 2, 1994.
         (i)     Registrant's Annual Report on Form 10-K for the fiscal year
                 ended December 31, 1994.
         (j)     Registrant's Annual Report on Form 10-K for the fiscal year
                 ended December 31, 1996

All exhibit descriptions followed by a (+) indicate documents with respect to
which confidential treatment has been granted.

<PAGE>   1
                   FORM OF SEVERANCE COMPENSATION AGREEMENT
                   ----------------------------------------
                                                                  EXHIBIT 10.17
                                                                  -------------

                        SEVERANCE COMPENSATION AGREEMENT

SEVERANCE COMPENSATION AGREEMENT dated as of ______________ by and between
PROTEON, INC. and/or OpenROUTE Networks, Inc. (the "Company"), a Massachusetts
corporation with its principal offices at Nine Technology Drive, Westboro,
Massachusetts 01581, and ___________ (the "Executive"), residing at _________
________________________________.

     WHEREAS, the Company's Board of Directors has recognized that the
possibility of a change in control of the Company may cause uncertainty among
the Company's senior management and may result in the departure or distraction
of its senior management to the detriment of the Company and its stockholders;

     WHEREAS, the Company's Board of Directors has determined that it is
appropriate to reinforce and encourage the continued attention and dedication of
members of the Company's senior management, including the Executive, to their
duties without distraction arising from the possibility of a change in control
of the Company;

     WHEREAS, the Executive desires assurance as to his compensation and
benefits in the event of any change in control of the company;

     NOW, THEREFORE, in consideration of the covenants and agreements herein
contained and for other good and valuable consideration, the receipt and
adequacy of which are hereby acknowledged, the Company and the Executive agree
as follows:

     1. TERM. This Agreement shall terminate, except to the extent that any
obligation of the Company hereunder remains unpaid as of such time, upon the
earliest to occur of:

          (a) two (2) years from the date hereof;

          (b) the termination of the Executive's employment with the Company
based on (i) the death of the Executive, (ii) the Disability of the Executive,
(iii) termination by the Company for Cause, or (iv) termination by the Executive
other than for Good Reason; and

          (c) one year after the date of a Change in Control. As used in this
Agreement the term "Term" shall mean the period beginning on the date hereof and
ending upon the earliest to occur of events specified above.

<PAGE>   2

     2. CHANGE IN CONTROL. No compensation shall be payable under this Agreement
unless and until there shall have been a Change in Control. As used in this
Agreement, the term "Change in Control" means that any of the following events
has occurred:

     (i)  any person (as defined in Section 3(a)(9) of the Securities Exchange
          Act of 1934, as amended (the "1934 Act)) (or any successor provision),
          becomes the beneficial owner (determined in accordance with Rule 13d-3
          under the 1934 Act, or any successor provision), directly or
          indirectly, of more than fifty percent (50%) of the outstanding Common
          Stock of the Company, or otherwise becomes entitled to vote more than
          fifty percent (50%) of the voting power entitled to be cast at
          elections for directors ("Voting Power") of the Company;

     (ii) there shall have been consummated any consolidation or merger of the
          Company (A) in which the Company is not the continuing or surviving
          corporation unless such merger is with a corporation at least eighty
          percent (80%) of the Voting Power of which is held by the Company, or
          (B) pursuant to which the holders of the Company's shares of Common
          Stock immediately prior to such merger or consolidation are not the
          holders immediately after such merger or consolidation of at least a
          majority of the Voting Power of the entity resulting from such
          consolidation or merger;

     (iii) there shall have been consummated any sale, lease, exchange or other
          transfer (in one transaction or a series of related transactions) of
          all or substantially all of the assets of the Company; or

     (iv) during any period of two consecutive years, individuals who at the
          beginning of such period were members of the Board of Directors of the
          Company ceased for any reason to constitute a majority thereof, unless
          the election, or the nomination for election by the Company's
          stockholders, of each new director was approved by a vote of at least
          two-thirds of the directors still in office at the time of such
          election or nomination who were directors at the beginning of such
          Period.

As used in this definition of Change in Control, "Common Stock" means the Common
Stock, or if changed, the capital stock of the Company as it shall be
constituted from time to time entitling the holders thereof to share generally
in the distribution of all assets available for distribution to the Company's
stockholders


<PAGE>   3



after the distribution to any holders of capital stock with preferential rights.

3. TERMINATION FOLLOWING CHANGE IN CONTROL. The Executive shall be entitled to
the compensation provided in Section 4 hereof upon the termination of the
Executive's employment with the Company during the Term of this Agreement and
after a Change in Control unless such termination is as a result of (i) the
Executive's death, (ii) the Executive's Disability, (iii) termination by the
Company for Cause, or (iv) termination by the Executive other than for Good
Reason. As used in this Agreement, the following terms shall have the following
meanings:

     (a)  the term "Disability" shall mean that as a result of the Executive's
          incapacity due to physical or mental illness or physical injury
          (excluding illness or injury which was caused by repeated substance
          abuse by the Executive), the Executive shall have been absent from his
          duties with the Company on a full-time basis (i) for a period of sixty
          (60) consecutive days or (ii) for an aggregate of ninety (90) days
          during any period of twelve (12) consecutive months;

     (b)  the term "Cause" shall mean any of (i) the willful and continued
          failure by the Executive to perform his duties with the Company, other
          than any such willful or continued failure resulting from his
          incapacity due to physical or mental illness or physical injury
          (provided that if such willful and continued failure resulted from
          illness or injury which was caused by repeated substance abuse by the
          Executive, then the foregoing exception for physical or mental illness
          or physical injury shall not be applicable), (ii) the willful or
          knowingly reckless engaging by the Executive in misconduct which is
          materially injurious to the Company, financially or otherwise,
          including, without limitation, willful breach by the Executive of any
          employment or other agreement between the Executive and the Company,
          or (iii) the conviction of the Executive of a felony by a court of
          competent jurisdiction. For purposes of the foregoing, (x) the failure
          of the Company to achieve desired or projected results shall not
          constitute Cause, but Cause shall only mean and include acts and/or
          omissions by the Executive which are specified in clauses (i), (ii)
          and (iii) of the immediately preceding sentence, and (y) no act or
          failure to act on the part of the Executive shall be considered
          "willful" unless done or admitted to be done by him not in good faith
          and without reasonable belief that his action or omission was in the
          best interests

<PAGE>   4


          of the Company. Notwithstanding the first sentence of this
          subparagraph (b), the Executive's employment shall not be deemed to
          have been terminated for Cause unless (A) reasonable notice shall have
          been given to him setting forth in detail the reasons for the
          Company's intention to terminate for Cause and, if such termination is
          pursuant to clause (i) or (ii) above, only if the Executive has been
          provided a period of five (5) business days from receipt of such
          notice to cease the actions or inactions, and if he has not done so
          (B) an opportunity shall have been provided for the Executive,
          together with his counsel, to be heard before the Board of Directors
          of the Company, and (C) if such termination is pursuant to clause (i)
          or (ii) above, delivery shall have been made to the Executive of a
          Notice of Termination from the Board of Directors stating that in the
          good faith opinion of a majority of the Board of Directors (excluding
          the Executive) he was guilty of conduct set forth in clause (i) or
          (ii) above and specifying the particulars thereof in detail;

     (c)  the term "Good Reason" shall mean any of the following (without the
          Executive's express written consent):

          (i)  after a Change in Control, the assignment to the Executive by the
               Company of duties inconsistent with the Executive's position,
               duties, responsibilities and status with the Company immediately
               prior to such Change in Control, or a change in the Executive's
               titles or offices as in effect immediately prior to such Change
               in Control, or any removal of the Executive from or any failure
               to reelect the Executive to any of such positions, except in
               connection with the termination of his employment for Disability,
               for Cause, as a result of the Executive's death or by the
               Executive other than for Good Reason:

          (ii) after a Change in Control, a reduction by the Company in the
               Executive's base salary as in effect on the date hereof or as the
               same may be increased from time to time during the Term of this
               Agreement, or the Company's failure after a Change in Control to
               increase (within 12 months of the Executive's last increase in
               base salary) the Executive's base salary by an amount which, on a
               percentage basis, is not more than two percentage points below
               the average percentage increase in base salary effected in the
               preceding 12 months

<PAGE>   5

               for all officers of the Company having severance compensation
               agreements similar to this Agreement;

          (iii)after a Change in Control, any failure by the Company to continue
               in effect any benefit plan or arrangement (including, without
               limitation, the Company's group life insurance plan, and medical,
               dental, accident and disability plans) in which the Executive is
               participating at the time of a Change in Control (or any other
               substitute plans providing the Executive with substantially
               similar benefits) (hereinafter referred to as "Benefit Plans"),
               or the taking of any action by the Company which would adversely
               affect the Executive's participation in or materially reduce the
               Executive's benefits under any such Benefit Plan or deprive the
               Executive of any material fringe benefit enjoyed by the Executive
               at the time of a Change in Control;

          (iv) after a Change in Control, any failure by the Company to continue
               in effect any incentive plan or arrangement (including, without
               limitation, the Company's Management Incentive Plan, and the
               right to receive performance awards and similar incentive
               compensation benefits) in which the Executive is participating at
               the time of a Change in Control (or any other substitute plans or
               arrangements providing him with substantially similar benefits)
               (hereinafter referred to as "Incentive Plans") or the taking of
               any action by the Company which would adversely affect the
               Executive's participation in any such Incentive Plan or reduce
               the Executive's benefits under any such Incentive Plan, expressed
               as a percentage of his base salary, by more than 10 percentage
               points in any fiscal year as compared to the immediately
               preceding fiscal year;

          (v)  after a Change in Control, any failure by the Company to continue
               in effect any plan or arrangement to receive securities of the
               Company (including, without limitation, the Company's 1991
               Restated Stock Option Plan and any other plan or arrangement to
               receive and exercise stock options, stock appreciation rights,
               restricted stock or grants thereof) in which the Executive is
               participating at the time of a Change in Control of the Company
               (or substitute plans or arrangements providing him with
               substantially

<PAGE>   6

               similar benefits) (hereinafter referred to as "Securities Plans")
               or the taking of any action by the Company which would adversely
               affect the Executive's participation in or materially reduce the
               Executive's benefits under any such Securities Plans;

          (vi) after a Change in Control, requirement by the Company of the
               Executive's relocation to any place other than the location at
               which the Executive performed the Executive's duties prior to a
               Change in Control, except for required travel by the Executive on
               the Company's business to an extent substantially consistent with
               the Executive's business travel obligations at the time of a
               Change in Control;

          (vii) after a Change in Control, any failure by the Company to provide
               the Executive with the number of paid vacation days to which the
               Executive is entitled at the time of a Change in Control;

          (viii) any material breach by the Company of any provision of this
               Agreement;

          (xi) any failure by the Company to obtain the assumption of this
               Agreement by any successor or assign of the Company in accordance
               with Section 7 hereof: or

          (x)  any purported termination of the Executive's employment which is
               not effected pursuant to a Notice of Termination, and for
               purposes of this Agreement, no such purported termination shall
               be effective.

     (d)  The term "Notice of Termination" shall mean a written notice which
          shall indicate those specific termination provisions in this Agreement
          relied upon and which sets forth in reasonable detail the facts and
          circumstances claimed to provide a basis for termination of the
          Executive's employment under the provision so indicated. For purposes
          of this Agreement, no such purported termination by the Company shall
          be effective without such Notice of Termination.

     e)   the term "Date of Termination" shall mean (i) if the Executive's
          employment is terminated by the Company for Disability, 30 days after
          Notice of Termination is

<PAGE>   7
          given to the Executive (provided that the Executive shall not have
          returned to the performance of the Executive's duties on a full-time
          basis during such 30-day period) or (b) if the Executive's employment
          is terminated by the Company for any other reason, the date on which a
          Notice Of Termination is given; PROVIDED that if within 30 days after
          any Notice of Termination is given to the Executive by the Company the
          Executive notifies the Company that a dispute exists concerning the
          Termination, the Date of Termination shall be the date the dispute is
          finally determined, whether by mutual agreement by the parties or upon
          final judgment, order or decree of a court of Competent jurisdiction
          (the time for appeal therefrom having expired and no appeal having
          been perfected).


4, SEVERANCE COMPENSATION

(a) Subject to the provisions of section 4(b) below, and subject to the
Executive's continuing compliance with the provisions of Section 6 hereof and
the Agreement Regarding Confidential Information and Intellectual Property
attached hereto as EXHIBIT A, the compensation and benefits payable to the
Executive pursuant to this Agreement shall be the following (collectively the
"Severance Benefits"):

     (i}  The Company shall pay to the Executive in cash an amount equal to the
          Executive's aggregate compensation from the Company for the twelve
          (12) months ending upon the Change in Control. Such amount shall be
          payable by, the Company in twelve (12) equal monthly installments
          payable on the first day of each month commencing with the month
          following the Executive's Date of Termination. For purposes of this
          Section 4(a)(1), the. Executive's "compensation" preceding a Change in
          Control shall include the Executive's base salary and any amounts paid
          or accrued pursuant to any Incentive Plans, but shall not include any
          amounts or benefits paid or accrued pursuant to any Benefit Plans or
          any Securities Plan nor shall it include the value of any other fringe
          benefits,

     (ii} Within thirty (30) days following the Date of Termination, the Company
          shall pay to the Executive, in a lump sum in cash, any accrued but
          unpaid salary, vacation and awards under any Incentive Plans earned
          but not paid as of the Date of Termination;

<PAGE>   8

     (iii)Effective not later than the Date of Termination, the Company shall
          (notwithstanding any contrary provision in any Securities Plan or any
          employment agreement) accelerate and make immediately exercisable in
          full all unvested options and other rights which the Executive holds
          under any Securities Plans as of the Date of Termination, and all such
          options and rights shall be exercisable for an exercise period of 60
          days following the Date of Termination; and

     (iv) The Company at its own expense shall maintain in full force and effect
          for the Executive's continued benefit until the earlier of (i) one (1)
          year after the Date of Termination or (ii) the Executive's
          commencement of full-time employment with a new employer, medical and
          dental (but not life insurance or disability) plans, programs or
          arrangements in which the Executive was entitled to participate
          immediately prior to the Date of Termination, provided that his
          continued participation is possible under the general terms and
          provisions of such plans and programs. In the event that his
          participation in any such plan or program is barred, the Company shall
          arrange to provide the Executive with benefits substantially similar
          to those to which he was entitled to receive under such plans and
          programs.

(b) Notwithstanding the foregoing, any Severance Benefits otherwise payable to
the Executive hereunder shall be limited as follows:

     (I)  No Severance Benefits shall be payable to the Executive under this
          Agreement to the extent that the total of such Severance Benefits and
          any payments otherwise payable to the Executive by the Company on or
          after a Change in Control, which would be deemed under Section 280 (of
          the Internal Revenue Code of 1986 as amended (the "Code"), to
          constitute "parachute payments" without regard to Section
          280G(b)(2)(A)(ii), would equal or exceed in their present value (as
          determined under Section 280G(d)(4) of the Code and any regulations
          thereunder) 300% of the Executive's base amount (as defined in Section
          280G(b)(3) of the Code and regulations thereunder). In the event
          that the present value of such payments equals or exceeds such amount,
          the provisions set forth below will apply, and Severance Benefits
          payable to the Executive under this Agreement will be made only in
          accordance with this Section 4(b) notwithstanding any other provision
          to the contrary in this Agreement.

<PAGE>   9

     (ii) Not later than thirty (30) days after the Date of Termination, the
          Company will provide the Executive with a schedule specifying the
          present value of such Severance Benefits payable to the Executive
          under this Agreement (specifying the Section hereof under which each
          such payment is to be made) and any other payments otherwise payable
          to the Executive by the Company on or after the Change in Control
          which, in the Company's opinion, could constitute parachute payments
          under Section 280G. No payments under this Agreement shall be made
          until after thirty (30) days from the receipt of such schedule by the
          Executive. At any time prior to the expiration of said 30-day period,
          the Executive shall have the right to select from all or part of any
          category of payment to be made under this Agreement those payments to
          be made to the Executive in an amount the present value of which (when
          combined with the present value of any other payments otherwise
          payable to the Executive by the Company that may be deemed to be
          parachute payments) the Company determines is less than 300% of the
          Executive's base amount. If the Executive fails to exercise his right
          to make a selection, the selection shall be made by the Company.

     (iii) At any time prior to exercising the right to make a selection under
          paragraph (ii) of this Section 4(b), the Executive shall have the
          right to request that the Company obtain a ruling from the Internal
          Revenue Service ("Service") as to whether any or all payments listed
          on the schedule provided hereunder are, in the view of the Service,
          parachute payments under section 280G. Such ruling shall be sought
          made at the Company's expense unless, in the written opinion of
          independent counsel for the Company, there is no reasonable likelihood
          of obtaining a favorable ruling, in which event such expense shall be
          borne by the Executive. If a ruling is sought pursuant to such
          request, no Severance Benefit under this Agreement shall be paid to
          the Executive until after thirty (30) days from the date the Company
          provides the Executive with a copy of such ruling, and the period
          during which the Executive may exercise his right to make a selection
          under paragraph (ii) hereof shall be extended to a date thirty (30)
          days from such date. For purposes of this Section 4(b), the Executive
          and the Company hereby agree to be bound by the Service's ruling as to
          whether payments constitute parachute payments under Section 280G. If
          the Service declines, for any reason, to provide the ruling requested,
          the Company's

<PAGE>   10

          determination with respect to what payments constitute parachute
          payments shall control, and the period during which the Executive may
          exercise his right to make a selection under paragraph (ii) hereof
          shall be extended to a date thirty (30) days from the date of the
          Service's notice indicating that no ruling will be forthcoming.

     (iv) The references to Section 280G herein are specific references to
          Section 280G as amended to date. If Section 280G is amended prior to
          the expiration or termination of this Agreement, or replaced by a
          successor statute, the limitations imposed by this Section 4(b) upon
          payments to be made to the Executive under this Agreement shall be
          deemed modified without further action of the parties so as to provide
          only for such limitations that are consistent with such amendment(s)
          or successor statute(s), as the case may be. In the event that Section
          280G, or any successor statute, is repealed, this Section 4(b) shall
          cease to be effective on the date of such repeal. The parties to this
          Agreement recognize that final Treasury Regulations under Section 280G
          may affect the amounts that may be paid hereunder and agree that, upon
          issuance of such final Regulations, this Agreement may be modified as
          in good faith deemed necessary in light of the provisions of such
          Regulations to achieve the purposes hereof, and that consent to such
          modification(s) shall not be unreasonably withheld


5. NO OBLIGATION TO MITIGATE DAMAGES; NO EFFECT ON OTHER CONTRACTUAL RIGHTS.

(a) The Executive shall not be required to mitigate damages or the amount of any
payment provided for under this Agreement by seeking other employment or
otherwise, nor shall the amount of any payment provided for under this Agreement
be reduced by any compensation earned by the Executive as the result of
employment by another employer after the Date of Termination, or otherwise.

(b) The provisions of this Agreement, and any payment provided for hereunder,
shall not reduce any amounts otherwise payable, or in any way diminish the
Executive's existing rights, or rights which would accrue solely as a result of
the passage of time, under any Benefit Plan, Incentive Plan or Securities Plan,
employment agreement or other contract, plan or arrangement.


<PAGE>   11



6. NON-COMPETITION; CONFIDENTIALITY.

(a) The Executive covenants and agrees that if the Executive shall become
entitled to compensation hereunder as provided in Section 3 hereof, then for a
period of twelve (12) months following the Date of Termination, the Executive
shall not, without the Company's prior written consent, engage, directly or
indirectly, in any work or other activity which is in competition with the
business of the Company in the local area network or internetworking field in
any geographical area in which the Company conducts or is then actively planning
to conduct business at the Date of Termination. By way of example only of the
types of activities prohibited hereby, the Executive shall not: solicit or
accept (or assist any person or entity in soliciting or accepting) any business
in the local area network or internetworking field from any person or entity who
or which was an active account of the Company at the Date of Termination

(b) Contemporaneously with the execution and delivery of this Agreement, the
Executive and the Company shall enter into an Agreement Regarding Confidential
Information and Intellectual Property in the Company's standard form, a copy of
which is attached hereto as EXHIBIT A.

7. SUCCESSORS.

(a) The Company will require any successor or assign (whether direct or
indirect, by purchase, merger, consolidation or otherwise) to all or
substantially all of the business and/or assets of the Company, by agreement in
form and substance satisfactory to the Executive, expressly, absolutely and
unconditionally to assume and agree to perform this Agreement in the same manner
and to the same extent that the Company would be required to perform it if no
such succession or assignment had taken place. Any failure of the Company to
obtain such agreement prior to the effectiveness of any such succession or
assignment shall be a material breach of this Agreement and shall entitle the
Executive to terminate the Executive's employment for Good Reason. As used in
this Agreement, "Company" shall mean the Company as herein before defined and
any successor or assign to its business and/or assets as aforesaid which
executes and delivers the agreement provided for in this Section 7 or which
otherwise becomes bound by all the terms and provisions of this Agreement by
operation of law. If at any time during the Term of this Agreement the Executive
is employed by any corporation a majority of the Voting Power of which is then
owned by the Company, directly or indirectly, "Company" as used in Sections 3,4
and 12 hereof shall in addition include such employer. In such event, the
Company agrees that it shall pay or shall cause

<PAGE>   12

such employer to pay any amounts owed to the Executive pursuant to Section 4
hereof

(b) This Agreement shall inure to the benefit of and be enforceable by the
Executive's personal and legal representatives, executors, administrators,
successors, heirs, distributees, devisees and legatees. If the Executive should
die while any amounts are still payable to him hereunder, all such amounts,
unless otherwise provided herein, shall be paid in accordance with the terms of
this Agreement to the Executive's devisee, legatee, or other designee or, if
there be no such designee, to the Executive's estate.

8. NOTICE. For purposes of this Agreement, notices and all other communications
provided for in the Agreement shall be in writing and shall be deemed to have
been duly given when delivered in person (including by any commercial courier
service) or three (3) days after mailing by United States certified or
registered mail, return receipt requested, postage prepaid, to a party at his or
its address set forth at the beginning of this Agreement or such other address
as either party may have furnished to the other in writing in accordance
herewith, except that notices of change of address shall be effective only upon
receipt.

9. MISCELLANEOUS. No provisions of this Agreement may be modified, waived or
discharged unless such waiver, modification or discharge is agreed to in writing
signed by the Executive and the Company. No waiver by either party hereto at any
time of any breach by the other party hereto of, or compliance with, any
condition or provision of this Agreement to be performed by such other party
shall be deemed a waiver of similar or dissimilar provisions or conditions at
the same or at any prior or subsequent time. No agreements or representations,
oral or otherwise, express or implied, with respect to the subject matter hereof
have been made by either party which are not set forth expressly in this
Agreement. This Agreement shall be governed by and construed in accordance with
the laws of the Commonwealth of Massachusetts (without regard to conflicts of
laws rules).

10. VALIDITY. The invalidity or unenforceability of any provisions of this
Agreement shall not affect the validity or enforceability of any other provision
of this Agreement, which shall remain in full force and effect

11. COUNTERPARTS. This Agreement may be executed in one or more counterparts,
each of which shall be deemed to be an original but all of which together will
constitute one and the same instrument.

<PAGE>   13

12. LEGAL FEES AND EXPENSES. The Company shall pay all legal fees and expenses
which the Executive may incur as a result of the Company's contesting the
validity, enforceability or the Executive's interpretation of, or determinations
under, this Agreement.

13. FURTHER ASSURANCES. The Company shall do, make, execute and deliver all such
additional and further acts, things, assurances and instruments as the Executive
may reasonably request in order to assure to the Executive his rights hereunder
and to carry into effect the provisions and intent of this Agreement. Without
limiting the generality of the foregoing, the Company shall, upon request of the
Executive, convert any options under any Securities Plan which are "incentive
stock options" into "non-qualified options" and amend outstanding option
agreements in a manner not inconsistent with such Securities Plans

IN WITNESS WHEREOF, the parties have executed this Severance Compensation
Agreement as of the date first above written.

                                 PROTEON, INC.

                                 BY: /s/ Daniel J. Capone, Jr.
                                     ------------------------------------------
                                     Title: President & Chief Executive Officer

                                 BY: /s/ 
                                     ------------------------------------------
                                     Executive

<PAGE>   1

                                                                   EXHIBIT 10.18

                               AMENDMENT TO LEASE
                               ------------------

     This Amendment to Lease (the "Amendment") dated as of May 23, 1997 by and
between WCB TWENTY LIMITED PARTNERSHIP, a Delaware limited partnership
("Landlord") and PROTEON, INCORPORATED ("Tenant").

                                  WITNESSETH:

     WHEREAS, Landlord is the landlord and Tenant is the tenant under that
certain Lease dated December 19, 1994 (the "Lease"), pursuant to which the
Tenant leases 96,166 square feet of rentable space in the building known as and
numbered Nine Technology Drive, Westborough, Massachusetts; and

     WHEREAS, Landlord and Tenant desire to amend the Lease by deleting 52,204
square feet of rentable space from the Premises demised under the Lease, and by
making certain other amendments to the terms and provisions of the Lease, all
as more fully set forth herein;

     NOW, THEREFORE, in consideration of the foregoing and for other good and
valuable consideration, the receipt and sufficiency of which are hereby
mutually acknowledged, Landlord and Tenant hereby confirm and mutually agree as
follows:

     1.  DEFINITIONS.  Unless otherwise defined herein, all capitalized terms
used in this Amendment to Lease shall have the definitions ascribed to them in
the Lease.

     2.  EFFECTIVE DATE.  This Amendment to Lease shall take effect as of 12:01
am on May 23, 1997 (the "Effective Date").

     3.  TERM EXPIRATION DATE.  The definition of "INITIAL TERM EXPIRATION
DATE" set forth in Section 1.1 of the Lease shall remain unchanged, such
Initial Term Expiration Date being 12:00 midnight on April 30, 2002.

     4.  EXTENSION TERMS.  The provisions of Section 2.4.1 of the Lease shall
remain unchanged.

     5.  PREMISES.  Effective as of the Effective Date, the definition of
"PREMISES" set forth in Section 1.1 of the Lease shall be deleted in its
entirety and the following inserted in its place:

     "PREMISES:               The Premises, comprising 43,962 square feet
                              of Rentable Floor Area on the first floor of the 
                              Building, are outlined on Exhibit A attached
                              hereto and incorporated by reference herein."

     6.  RENTABLE FLOOR AREA.  Effective as the Effective Date, the definition
of "RETABLE FLOOR AREA OF PREMISES" shall be deleted in it entirety and the
following inserted in its place:

     "RENTABLE FLOOR AREA
      OF PREMISES:                   43,962 square feet."

     7.  TENANT'S PROPORTIONATE SHARE.  Effective as of the Effective Date,
the definition of "TENANT'S PROPORTIONATE SHARE" set forth in Section 1.1 of
the Lease shall be deleted in its entirety and the following inserted in its
place:

     "TENANT's PROPORTIONATE
      SHARE:                         Seventeen and 53/100 percent (17.53%),
                                     being the ratio of the Rentable Floor
                                     Area of the Premises to the Rentable Floor 
                                     Area of the Building."

     8.  PLAN OF PREMISES.  Effective as of the Effective Date, Exhibit A of
the Lease shall be deleted in its entirety and the new Exhibit A attached
hereto shall be inserted in its place.

     9.  PARKING.  Effective as of the Effective Date, Tenant acknowledges and
agrees that Landlord shall have the right to assign and designate 10 parking
spaces adjacent to the exit door of Stairwell #5 of the Building for the
exclusive use of The TJX Companies, Inc. ("TJX").

    10.  VACATION OF SPACE.  On or before the Effective Date, Tenant shall
vacate the deliver to Landlord those portions of the 96,166 square feet of
Rentable Floor Area that Tenant currently occupies which are not part of the
Premises as defined in Section 5 above and described on Exhibit A attached
hereto (being 52,204 square feet of Rentable Floor Area, herein referred to as
the "Vacated Space"), time being of the essence. Tenant shall deliver the
Vacated Space in its "AS IS" condition, free of all of its personal property
and trade fixtures (except with respect to the cafeteria and exercise room on
the first floor, both of which are the subject of a separate agreement between
Tenant and TJX) HVAC, plumbing and electrical and mechanical systems included
in the Vacated Space in good working order and repair.

    11.  CONDITIONS PRECEDENT.  This Amendment to Lease is subject to
conditioned in all respects upon the execution and delivery of a Lease between
Landlord and TJX pursuant to which TJX shall lease the Vacated Space (the "TJX
Lease"). In the event that Landlord and TJX do not execute and deliver a Lease
for the Vacated Space on or before the Effective Date, this Amendment to Lease
shall be null and void and of no further force and effect.
  
<PAGE>   2

     12. PAYMENTS BY TENANT.  Tenant acknowledges and agrees that is shall be
responsible for, and shall pay (i) to Landlord, a lump sum payment on or before
the Effective Date in an amount equal to the Fixed rent and Additional Rent for
the Vacated Space for the period commencing May 23, 1997 through and including
July 14, 1997, and (ii) all of the Landlord's costs, fees and expenses with
respect to the preparation of this Amendment to Lease and the TJX Lease,
including, without limitation, the fees and expenses of Landlord's counsel in
connection with same.

     13. BROKERAGE.  Landlord and Tenant each represent and warrant to the other
that it has not engaged any broker or similar agent in connection with this
Amendment to Lease or the TJX Lease except Whittier Partners, the Columbia Group
and Lynch, Murphy & Partners. Tenant acknowledges and agrees that it shall be
responsible for and shall pay directly the brokerage commissions and fees in
connection with this Amendment to Lease and the TJX Lease, including any
commissions and fees due and owing Whittier Partners, the Columbia Group or
Lynch, Murphy & Partners, and Tenant agrees to indemnify and hold Landlord
harmless from and against any claim against Landlord for brokerage commission or
fees in connection with this Amendment to Lease or the TJX Lease (i) by Whittier
Partners, the Columbia Group or Lynch, Murphy & Partners, or (ii) by any other
broker or similar agent with which Tenant has dealt in connection with this
Amendment to Lease or the TJX Lease or the transactions contemplated hereby or
thereby.

     14.  EFFECT OF AMENDMENT.  Except as set forth herein, the lease shall
remain unchanged and in full force and effect. All references to the "Lease"
shall be deemed to be references to the Lease as amended by this Amendment to
the Lease.

                                      
<PAGE>   3
     IN WITNESS WHEREOF, Landlord and Tenant have caused this Amendment to
Lease to be executed by their duly authorized officers as an instrument under
seal as of the day and year first above written.




                                        LANDLORD

                                        WCB TWENTY LIMITED PARTNERSHIP
                                        a Delaware limited partnership

                                        By: WCB TWENTY, INC.
                                            a Delaware corporation



                                        By: /s/ JOHN M. MARKEY
                                           ------------------------------------ 
                                            John M. Markey
                                            Senior Vice President - East


                                        TENANT:

                                        PROTEON INCORPORATED           

                                        By: /s/ DANIEL J. CAPONE, JR.
                                           ------------------------------------ 
                                            Daniel J. Capone, Jr.
                                            President & CEO






<PAGE>   1
                                                                    EXHIBIT 11

                                  PROTEON, INC.
                                  STATEMENT RE:
                        COMPUTATION OF PER SHARE EARNING
                    (in thousands, except per share amounts)

<TABLE>
<CAPTION>

                                             Twelve months ended

                                   December 31,  December 31,  December 31,
                                      1997          1996          1995
                                    --------      --------      --------

<S>                                 <C>           <C>           <C>     
Net (Loss) Income                   ($ 7,847)     ($12,014)     $  8,220
                                    ========      ========      ========

Basic:

Weighted average number of
   common shares outstanding 
   used to calculate per share 
   data                               15,301        15,630        15,416
                                    ========      ========      ========


Diluted:

Weighted average number of
   common shares outstanding          15,301        15,630        15,416

Weighted average common
   equivalent shares                       -             -           276
                                    --------      --------      --------

Weighted average number of
   common and common equivalent
   shares outstanding used to
   calculate per share data           15,301        15,630        15,692
                                    ========      ========      ========

Net (loss) income per share
   Basic                            ($  0.51)     ($  0.77)     $   0.53
                                    ========      ========      ========

   Diluted                          ($  0.51)     ($  0.77)     $   0.52
                                    ========      ========      ========
</TABLE>


<PAGE>   1
Proteon, Inc.                                                    EXHIBIT 13

- ----------------------------------------
  SELECTED CONSOLIDATED FINANCIAL DATA
- ----------------------------------------

CONSOLIDATED STATEMENT OF OPERATIONS DATA:
- -------------------------------------------------------------------------------
<TABLE>
<CAPTION>
                                                                     Years ended December 31,
(in thousands, except per share data)              1997           1996           1995          1994           1993
- -------------------------------------------------------------------------------------------------------------------
<S>                                              <C>           <C>             <C>           <C>           <C>      
Net sales                                        $26,944       $ 45,296        $75,323       $93,912       $103,405
Cost of sales                                     15,340         25,670         36,664        48,148         61,723
- -------------------------------------------------------------------------------------------------------------------
Gross profit                                      11,604         19,626         38,659        45,764         41,682
Operating expenses:
  Research and development                         5,987          9,353          8,802        11,162         15,481
  Selling and marketing                           10,703         15,486         17,903        23,955         31,778
  General and administrative                       3,870          4,590          4,683         7,065         10,222
  Restructure costs                                 (241)         3,312              -         6,330          7,711
- -------------------------------------------------------------------------------------------------------------------
       Total operating expenses                   20,319         32,741         31,388        48,512         65,192
- -------------------------------------------------------------------------------------------------------------------
(Loss) income from operations                     (8,715)       (13,115)         7,271        (2,748)       (23,510)
Interest income (expense), net                     1,052          1,261          1,437           455            330
Other income                                           -              -              -         1,205              -
- -------------------------------------------------------------------------------------------------------------------
(Loss) income before income taxes                 (7,663)       (11,854)         8,708        (1,088)       (23,180)
Provision (benefit) for income taxes                 184            160            488           251         (3,385)
- -------------------------------------------------------------------------------------------------------------------
(Loss) income before cumulative effect of
  accounting change                               (7,847)       (12,014)         8,220        (1,339)       (19,795)
Cumulative effect of accounting change for
  income taxes                                         -              -              -             -            452
- -------------------------------------------------------------------------------------------------------------------
Net (loss) income                                $(7,847)      $(12,014)       $ 8,220       $(1,339)      $(19,343)
- -------------------------------------------------------------------------------------------------------------------

Basic (loss) income per share:
(Loss) income per share before
  cumulative effect of accounting change         $ (0.51)      $  (0.77)       $  0.53       $( 0.09)      $  (1.36)
Cumulative effect of accounting change for 
  income taxes                                         -              -              -             -           0.03
- -------------------------------------------------------------------------------------------------------------------
Basic (loss) income per common and
  common equivalent share                        $ (0.51)      $  (0.77)       $  0.53       $ (0.09)      $  (1.33)
- -------------------------------------------------------------------------------------------------------------------

Diluted (loss) income per share:
(Loss) income per share before
  cumulative effect of accounting change         $ (0.51)      $  (0.77)       $  0.52       $( 0.09)      $  (1.36)
Cumulative effect of accounting change for 
  income taxes                                         -              -              -             -           0.03
- -------------------------------------------------------------------------------------------------------------------
Diluted (loss) income per common and
  common equivalent share                        $ (0.51)      $  (0.77)       $  0.52       $ (0.09)      $  (1.33)
- -------------------------------------------------------------------------------------------------------------------
Weighted average number of common 
  shares outstanding                              15.301         15,630         15,416        14,808         14,527
Weighted average number of common and
  common equivalent shares outstanding            15,301         15,630         15,692        14,808         14,527
- -------------------------------------------------------------------------------------------------------------------

CONSOLIDATED BALANCE SHEET DATA:

Working capital                                  $23,620       $ 30,597        $39,006       $27,550       $ 20,698
Total assets                                      33,403         45,571         59,029        56,911         56,767
Stockholders' equity                              26,892         35,191         47,323        37,679         36,739
</TABLE>

<PAGE>   2


- -------------------------------------------------------------------------------
Management's Discussion and Analysis of Financial Condition and Results of
Operations
- -------------------------------------------------------------------------------
The following discussion and analysis should be read in conjunction with the
consolidated financial statements and notes thereto.

Results of Operations

During 1997 the Company continued to make progress in its transition from the
LAN business environment to the Internet Access marketplace. Although overall
product revenue decreased by 30.9% in 1997, the Company's GlobeTrotter Internet
Access product revenue increased by 76.5% on a unit sales increase of 92.7%.
Sales of GlobeTrotter products increased to 26.4% of total product revenue from
10.3% in 1996. The Company continued to experience losses in 1997 as the growth
of the GlobeTrotter product line was not sufficient to offset the 44.1% decline
in product revenue from LAN products and the winding up of the IBM and Digital
Equipment software licensing agreements. The 1997 operating loss reflects
approximately $880,000 or $0.06 per share of certain adjustments and accruals
relating to business operations in the ASIA-Pacific region as well as certain
employee incentive programs, both of which transpired in the fourth quarter of
1997. 

Net Sales
Product sales decreased by 30.9% to $22,248,000 in 1997 from $32,175,000 in
1996. This anticipated decline reflects Proteon's continuing product transition
from LAN products to Internet Access products. Although overall product revenue
declined in 1997, GlobeTrotter product revenue increased 76.5% from 1996 as a
result of increased unit sales. Corporate Enterprise and LAN product revenue
declined in 1997 by 43.3% from 1996 levels. Software licensing revenue in 1997
decreased by 88.1% to $895,000 from $7,530,000 in 1996 reflecting the declining
revenue produced from the IBM and Digital Equipment software licensing
agreements. The Company expects that it will continue to have software licensing
revenue in the future, however at varying and uncertain levels since software
licensing revenue is an ancillary component of the Company's core revenue stream
but strategic in its promotion of OpenROUTE routing technology in the
marketplace. Service and other sales in 1997 decreased by 32.0% to $3,801,000
from $5,591,000 in 1996. This decrease was primarily due to the reduction in
service contracts and upgrade revenue worldwide resulting from the Company's
transition to Internet Access products which require less support services.

Product sales decreased by 37.9% to $32,175,000 in 1996 from $51,810,000 in
1995. This decline was due to the Company's redirection of its business and
products. The Company experienced declining revenues in both its LAN products
and Corporate Enterprise product categories. The decrease in LAN products net
sales in 1996 was due primarily to lower average selling prices and declining
unit volumes of Adapter Cards, Switches and Hubs. The Corporate Enterprise
reduction was due to a planned reduction in CNX backbone router as the Company
shifted to Internet Access routers. Although in 1996 total units in the Internet
Access category increased 63.3% from 1995 due primarily to GlobeTrotter sales
which are typically lower average per unit sales prices, this increase was not
enough to offset the decline in product revenues in the LAN and Corporate
Enterprise categories. Software licensing sales in 1996 decreased by 47.3% to
$7,530,000 from $14,284,000 in 1995. This anticipated reduction in software
licensing revenue was a result of the continued decline in remaining revenue
from the near completion of two major multi-year agreements with IBM and Digital
Equipment Corporation. The Company expected software licensing revenue from
these agreements to decrease quarterly as the contracts neared completion.
Service and other sales in 1996 decreased by 39.4% to $5,591,000 from $9,229,000
in 1995. This decrease was primarily due to the reduction in service spares and
upgrades revenue worldwide as corporate enterprise sales decreased.
International sales accounted for approximately 35.4%, 38.3%, and 35.7% of net
sales in 1997, 1996, and 1995, respectively.

GROSS PROFIT
Total gross profit margin decreased slightly in 1997 to 43.1% from 43.3% in
1996. Gross margin on product revenue improved significantly to 42.8% in 1997
from 35.3% in 1996 principally due to the expansion of the GlobeTrotter product
line into a number of higher margin models as well as to reductions in
manufacturing overhead expenses. Gross margin on service and other revenues also
increased to 31.1% in 1997 from 23.0% in 1996 primarily due to improved
efficiencies in the customer service area. However, these improvements were not
sufficient to offset the substantial decline in software licensing revenue which
is highly profitable. Total gross profit margin decreased in 1996 to 43.3% from
51.3% in 1995. Gross profit margin from the

<PAGE>   3

Company's software licensing and service and other sales increased in 1996 to
63.1% from 60.5% in 1995 due primarily to the decreased engineering efforts
related to existing agreements. Gross profit margin on product sales decreased
in 1996 to 35.3% from 47.2% in 1995 due mainly to both declining margins and
volume decreases in token ring adapter card segment of the LAN product category.
During the fourth quarter of 1996, the Company recorded an additional inventory
provision of $2,400,000 to reflect further inventory exposures as the Company
transitioned from LAN to Internet Access products.

RESEARCH AND DEVELOPMENT

The Company considers product development expenditures to be critical to future
revenues. These activities are closely related to product enhancement and new
product development. The Company's strategy also includes joint development
partnerships to bring new technologies and products to market. All of the
Company's research and development costs to date have been expensed as incurred.

     Research and development expenses were $5,987,000 or 22.2%, $9,353,000 or
20.6%, and $8,802,000 or 11.7% of net sales in 1997, 1996 and 1995,
respectively. The decrease in expenses of $3,366,000 in 1997 from 1996 was
primarily due to lower personnel and personnel-related costs as well as a more
defined focus on the Internet Access products only. When comparing 1996 to 1995,
the increase of $551,000 in research and development expenses was due to the
reallocation of engineering efforts from software licensing contracts to
internally funded development.

     Major efforts in 1997 included the continuing development of the
GlobeTrotter series of products with the introduction of several new models
during the year.

     During 1996, the Company initiated the GlobeTrotter series, as well as the
continued development of the RBX router, the CSX 900ER routing and switching
product, the CSX 900E Ethernet switch/repeater and the CSX 901T Token Ring
Switch.

SELLING AND MARKETING

Selling and marketing expenses were $10,703,000 or 39.7%, $15,486,000 or 34.2%,
and $17,903,000 or 23.8% of net sales in 1997, 1996 and 1995, respectively. The
decrease in expenses in 1997 from 1996 of $4,783,000 was primarily the result of
lower personnel and personnel-related costs including sales commissions due to
the decline in revenues in 1997 from 1996. However, 1997 selling and marketing
expenses as a percentage of net sales increased when compared to 1996 in part
due to the effort to promote the new Internet Access products. In 1996 sales and
marketing expenses decreased by $2,417,000 when compared to 1995. This decrease
was due mainly to lower personnel and personnel-related costs as well as a
reduction in advertising expenses for 1996.

GENERAL AND ADMINISTRATIVE

General and administrative expenses were $3,870,000, $4,590,000, and $4,683,000
in 1997, 1996 and 1995, respectively. When comparing 1997 to 1996, the decrease
in expenses of $720,000 was largely due to lower personnel and personnel-related
costs. During 1996, general and administrative expenses decreased by $93,000
when compared to 1995. This slight decrease was also due to a lower level of
personnel and personnel-related costs for 1996.

RESTRUCTURING OF OPERATIONS

The Company's management continually reviews methods to reduce its expense base
in response to decreased revenue streams. As a result, the Company has
implemented a series of restructurings, the most recent of which transpired in
1996. This restructuring of operations was necessary to reestablish the
strategic direction of the Company and better align its operating expenses with
anticipated revenues.

     In the fourth quarter of 1996, the Company recorded a $3,312,000
restructuring charge in connection with its strategic redirection of the
Company's business to the Internet Access marketplace. This charge included
approximately $410,000 of severance costs, approximately $785,000 to reduce the
Company's occupancy requirements, approximately $1,922,000 associated with the
disposal of fixed assets, and $195,000 of other costs. During 1996 the cash
impact for restructuring was insignificant and as of December 31, 1996 there was
an accrual of $1,661,000 relating to future spending.

     During 1997, the Company incurred cash expenditures in connection with the
1996 restructuring of approximately $495,000 for severance and payroll related
costs, approximately $672,000 as a result of reducing its occupancy costs and
$253,000 in other restructuring related costs. Management has determined that
all of the Company's obligations from

<PAGE>   4

the 1996 and prior restructurings have been settled. Accordingly, the Company
reversed its remaining restructuring provision of $241,000 in the third quarter
of 1997.

PROVISION FOR INCOME TAXES

In 1997, the Company recorded an income tax provision of $184,000 primarily 
due to foreign taxes on income earned outside the United States. The difference 
between the effective tax rate and the statutory tax rate for 1997 is mainly 
due to net operating loss carryforwards whose future realization is uncertain.

    In 1996, the Company recorded an income tax provision of $160,000, primarily
due to foreign taxes on income earned outside the United States. The difference 
between the effective tax rate and the statutory tax rate for 1996 is also due 
primarily to net operating loss carryforwards whose future realization is 
uncertain.


    In 1995, the Company recorded an income tax provision $488,000 principally
associated with alternative minimum tax, and state and foreign taxes. The
difference between the effective tax rate and the statutory tax rate in 1995 is
due primarily to the utilization of net operating loss carryforwards in 1995.

YEAR 2000

The Company is reviewing all systems and equipment which may be affected by the 
Year 2000 issue. Management is also in the process of developing an action plan 
that provides for the repair or replacement of all systems with exposure to Year
2000 problems by the end of 1998, the cost of which is not expected to have a 
material financial impact on the Company. The plan calls for a combination of 
internal and external resources. The commitment of internal resources is not 
expected to have a significant impact on the Company's future sales and 
operating results.

NEWLY ISSUED ACCOUNTING STANDARDS

The FASB recently issued Statement No. 130 ("SFAS 130") "Reporting Comprehensive
Income." This Statement requires changes in comprehensive income to be shown in
a financial statement that is displayed with the same prominence as other
financial statements. While not mandating a specific financial statement format,
the Statement requires that an amount representing total comprehensive income be
reported. The Statement will become effective for periods beginning after
December 15, 1997. Reclassification of financial statements for earlier periods
is required for comparative purposes. The Company does not believe that the
adoption of SFAS 130 will have a material impact on its result of operations.

The FASB also issued Statement No. 131 ("SFAS 131"), "Disclosures about Segments
of an Enterprise and Related Information". This Statement, which supersedes
Statement No. 14 "Financial Reporting for Segments of a Business Enterprise,"
changes the way public companies report information about segments. The
Statement, which is based on the management approach to segment reporting,
includes requirements to report segment information quarterly and entity-wide
disclosures about products and services, major customers, and the material
countries in which the entity holds assets and reports revenues. The Statement
is effective for periods beginning after December 15, 1997. Restatement for
earlier years is required for comparative purposes unless impracticable. In
addition, SFAS 131 need not be applied to interim periods in the initial year;
however, in subsequent years, interim period information must be presented on a
comparative basis. The Company is currently evaluating this Statement and its
effect on financial statement disclosures.

LIQUIDITY AND CAPITAL RESOURCES

During 1997, the Company's working capital decreased to $23,620,000 from
$30,597,000 in 1996. Cash, cash equivalents and marketable securities
constituted $17,760,000 of the $23,620,000 in working capital at December 31,
1997.
<PAGE>   5

     Cash consumed by operating activities decreased by $2,789,000 in 1997 from
1996. This change was due mainly to a smaller net operating loss in 1997 of
$8,715,000 when compared to the 1996 net operating loss of $13,115,000,
reducing cash consumption by $4,400,000. Also contributing to the change was a
reduction in inventory levels at year end 1997 of $3,027,000 when compared to
year end 1996 inventory levels. However, these two significant reductions were
partially offset by a reduction in accounts payable and accrued expenses of 
$3,869,000.

     Cash consumed by investing activities increased by $4,533,000 in 1997 from
1996. This cash use was due primarily to marketable securities purchases
exceeding sales by $5,525,000 in 1997.

     The Company's management believes that its cash, cash equivalents and
marketable securities will satisfy its expected working capital and capital
expenditure requirements through the next twelve months.

SAFE HARBOR FOR FORWARD-LOOKING STATEMENTS

The 1997 Annual Report, including the President's Letter and the Management's
Discussion and Analysis of Financial Condition and Results of Operations,
contains forward-looking statements within the meaning of the "safe harbor"
provisions of the Private Securities Litigation Reform Act of 1995. These
forward-looking statements are based on management's current expectations and
involve a number of risks and uncertainties. The Company's future results remain
difficult to predict and may be affected by a number of factors including:
business conditions within the networking industry; timing of orders from, and
shipments to major customers; timing of new products introductions; acceptance
of products in the marketplace; increased competition; changes in manufacturing
costs; changes in the mix of product sales; and changes in world economic
conditions. Other risk factors are listed from time to time in the required
documents including the Company's annual report on Form 10-K, filed with the
SEC.

<PAGE>   6

PROTEON, INC.
Consolidated Balance Sheets
<TABLE>
<CAPTION>

                                                                                         As of December 31,
- ------------------------------------------------------------------------------------------------------------
(in thousands, except share data)                                                         1997          1996
- ------------------------------------------------------------------------------------------------------------
ASSETS
<S>                                                                                   <C>           <C>     
Current assets:
     Cash and cash equivalents                                                        $  5,317        16,612
     Marketable securities                                                              12,443         6,918
     Accounts receivable less reserve for doubtful accounts of $927 and
        $672 at December 31, 1997 and 1996, respectively                                 6,224         7,625
     Inventories                                                                         5,710         8,737
     Deposits and other assets                                                             437         1,085
- ------------------------------------------------------------------------------------------------------------
        Total current assets                                                            30,131        40,977
     Property and equipment, net                                                         3,272         4,594
- ------------------------------------------------------------------------------------------------------------
        Total assets                                                                  $ 33,403      $ 45,571
- ------------------------------------------------------------------------------------------------------------

LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
     Accounts payable                                                                 $  2,292      $  3,010
     Accrued compensation                                                                  765         1,075
     Accrued expenses                                                                    2,779         3,560
     Accrued restructuring costs                                                             -         1,661
     Accrued warranty                                                                      675         1,074
- ------------------------------------------------------------------------------------------------------------
        Total current liabilities                                                        6,511        10,380

Commitments and Contingencies (Note F)                                                                         -             -

Stockholders' equity:

     Preferred stock, par value $.01, authorized 7,500,000 shares                            -             -
     Common stock, par value $.01 per share, authorized 30,000,000 shares, issued
     15,669,524 and 15,637,670 shares at December 31, 1997 and 1996, respectively          157           156
     Capital in excess of par value                                                     49,347        49,292
     Accumulated deficit                                                               (21,666)      (13,819)
     Cumulative translation adjustments                                                    110           177
     Less treasury stock, at cost, 397,435 shares and 210,685 shares                    (1,056)         (615)
        at December 31, 1997 and 1996, respectively 
- ------------------------------------------------------------------------------------------------------------
        Total stockholders' equity                                                      26,892        35,191
- ------------------------------------------------------------------------------------------------------------
        Total liabilities and stockholders' equity                                    $ 33,403      $ 45,571
- ------------------------------------------------------------------------------------------------------------
</TABLE>

The accompanying notes are an integral part of the consolidated financial
statements.
<PAGE>   7

PROTEON, INC.
Consolidated Statements of Operations

<TABLE>
<CAPTION>

                                           For the years ended December 31,
- ----------------------------------------------------------------------------
(in thousands, except per share data)      1997          1996          1995
- ----------------------------------------------------------------------------
Sales:
<S>                                      <C>          <C>            <C>     
     Product                             $22,248      $ 32,175       $51,810
     Software licensing                      895         7,530        14,284
     Service and other                     3,801         5,591         9,229
- ----------------------------------------------------------------------------
        Net sales                         26,944        45,296        75,323

Cost of sales:
     Product                              12,722        20,825        27,373
     Software licensing                        -           538         2,656
     Service and other                     2,618         4,307         6,635
- ----------------------------------------------------------------------------
        Cost of sales                     15,340        25,670        36,664
- ----------------------------------------------------------------------------

     Gross profit                         11,604        19,626        38,659

Operating expenses:
     Research and development              5,987         9,353         8,802
     Selling and marketing                10,703        15,486        17,903
     General and administrative            3,870         4,590         4,683
     Restructure costs                      (241)        3,312             -
- ----------------------------------------------------------------------------
        Total operating expenses          20,319        32,741        31,388
- ----------------------------------------------------------------------------

(Loss)/income from operations             (8,715)      (13,115)        7,271
Interest income                            1,052         1,271         1,490
Interest expense                               -           (10)          (53)
- ----------------------------------------------------------------------------
(Loss)/income before income taxes         (7,663)      (11,854)        8,708
Provision for income taxes                   184           160           488
- ----------------------------------------------------------------------------
Net (loss)/income                        ($7,847)     ($12,014)       $8,220
- ----------------------------------------------------------------------------
(Loss)/earnings per share -- Basic        ($0.51)       ($0.77)        $0.53
                                         -----------------------------------
  Weighted average number of       
  common shares outstanding -- Basic      15,301        15,630        15,416
- ----------------------------------------------------------------------------
(Loss)/earnings per share -- Diluted      ($0.51)       ($0.77)        $0.52
                                         -----------------------------------
   Weighted average number of common and      
    common equivalent shares outstanding
    -- Diluted                            15,301        15,630        15,692
- ----------------------------------------------------------------------------
</TABLE>



The accompanying notes are an integral part of the consolidated financial
statements.
<PAGE>   8

PROTEON, INC.
CONSOLIDATED STATEMENT OF STOCKHOLDER'S EQUITY

<TABLE>
<CAPTION>

                                         Common stock
                               -----------------------------------
                                                        Capital in                 Cumulative     Treasury stock       Total
                                                        excess of    Accumulated   translation   -----------------  stockholders'
(in thousands)                 Shares       Amount      par value      deficit     adjustment     Shares    Amount     equity
- --------------------------------------------------------------------------------------------------------------------------------
                                                                                                         
<S>                             <C>       <C>            <C>          <C>              <C>         <C>    <C>          <C>
BALANCE, DECEMBER 31, 1994      15,315        $153       $47,884      ($10,025)        ($46)        81      ($287)     $37,679
                                                                                                         
Issuance of common stock           274           3         1,257                                                         1,260
Currency translation                                                                    164                                164
Net income                                                               8,220                                           8,220
                                                                                                         
- ---------------------------------------------------------------------------------------------------------------------------------
BALANCE, DECEMBER 31, 1995      15,589         156        49,141        (1,805)         118         81       (287)      47,323
                                                                                                         
Issuance of common stock            48                       151                                                           151
Repurchase of stock as                                                                                   
  treasury stock                                                                                   130       (328)        (328)
Currency translation                                                                     59                                 59
Net loss                                                               (12,014)                                        (12,014)
                                                                                                         
- --------------------------------------------------------------------------------------------------------------------------------
BALANCE, DECEMBER 31, 1996      15,637         156        49,292       (13,819)         177        211       (615)      35,191
                                                                                                         
Issuance of common stock            33           1            55                                                            56
Repurchase of stock as                                                                                   
  treasury stock                                                                                   186       (441)        (441)
Currency translation                                                                    (67)                               (67)
Net loss                                                                (7,847)                                         (7,847)
                                                                                                         
- ---------------------------------------------------------------------------------------------------------------------------------
BALANCE, DECEMBER 31, 1997      15,670        $157       $49,347      ($21,666)        $110        397    ($1,056)     $26,892
- ---------------------------------------------------------------------------------------------------------------------------------
</TABLE>


The accompanying notes are an integral part of the consolidated financial
statements.
<PAGE>   9

PROTEON, INC.
Consolidated Statements of Cash Flows
<TABLE>
<CAPTION>

                                                               For the years ended December 31,
- -----------------------------------------------------------------------------------------------
(in thousands)                                                 1997          1996          1995
- -----------------------------------------------------------------------------------------------
<S>                                                        <C>           <C>           <C>
Cash flows provided by operating activities:
Net income (loss)                                          $ (7,847)     $(12,014)     $  8,220
  Adjustments to reconcile net income (loss) to cash
  flows (consumed) provided by operating activities:
     Bad debt provision                                         439             -             -
     Inventory provision                                          -         2,374             -
     Depreciation and amortization                            1,550         3,401         4,185
     Restructuring cost                                           -         1,922             -
     Loss (gain) on disposition of fixed assets                 198          (117)          (44)
  Changes in assets and liabilities:
     Decrease (increase) in accounts receivable                 962         4,513          (152)
     Decrease (increase) in inventories                       3,027        (6,686)          598
     Decrease in deposits and other assets                      768           372         1,260
     Decrease in accounts payable and accrued expenses       (3,869)       (1,326)       (7,526)
                                                           ------------------------------------
Net cash (consumed) provided by operating activities         (4,772)       (7,561)        6,541
                                                           ------------------------------------

Cash flows consumed by investing activities:
     Proceeds from the sale of fixed assets                     182           117            82
     Capital expenditures                                      (728)       (1,600)       (2,411)
     Marketable securities sales and maturities              19,428        15,456         7,120
     Marketable securities purchases                        (24,953)      (15,511)      (11,883)
                                                           ------------------------------------
Net cash consumed by investing activities                    (6,071)       (1,538)       (7,092)
                                                           ------------------------------------

Cash flows (consumed) provided by financing activities
     Proceeds from the issuance of common stock                  56           151         1,260
     Purchase of treasury stock                                (441)         (328)            -
                                                           ------------------------------------
Net cash (consumed) provided by financing activities           (385)         (177)        1,260
Effect of exchange rate changes on cash                         (67)           59           164
                                                           ------------------------------------
Net (decrease) increase in cash and cash equivalents        (11,295)       (9,217)          873
Cash and cash equivalents at beginning of year               16,612        25,829        24,956
                                                           ------------------------------------
Cash and cash equivalents at end of year                   $  5,317      $ 16,612      $ 25,829
                                                           ------------------------------------

Supplemental disclosure of cash flow information:
Non cash investing in finance activities:
     Note receivable on sale of fixed assets               $    120             -             -
     Interest paid during the year                                -      $     10      $     53
                                                           ------------------------------------
     Income taxes paid during the year                     $    230      $    321      $    344
                                                           ------------------------------------
</TABLE>

The accompanying notes are an integral part of the consolidated financial
statements.
<PAGE>   10


- -------------------------------------------------------------------------------
                   Notes To Consolidated Financial Statements
- -------------------------------------------------------------------------------

A. NATURE OF OPERATIONS

Proteon, Inc. and its subsidiaries including its wholly owned subsidiary
OpenROUTE Networks, Inc., develops, markets and supports a wide range of
networking products that encompass the Internet Access, Local Area Networking
and Remote Access components of the networking industry. The Company's
principal markets include North America, Europe and the Far East.

B. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Use of Estimates
To prepare the financial statements in conformity with generally accepted
accounting principles, management is required to make estimates and assumptions
that affect the reported amounts of assets and liabilities and disclosure of
contingent assets and assets and liabilities at the date of the financial
statements and the reported amounts of revenues and expenses during the
reporting period. In particular, the Company records reserves for estimated
product returns, as well as the estimated collectibility of accounts receivable,
estimated inventory obsolesence and estimated warranty obligations. All
estimates are based upon experience and actual results could differ from the
estimates and assumptions used by management.

Principles of Consolidation
The consolidated financial statements include the accounts of the Company and
its subsidiaries including its wholly owned subsidiary OpenROUTE Networks, Inc.
All intercompany transactions have been eliminated in consolidation.

Revenue Recognition
The Company recognizes revenue from product sales upon shipment of the product.
Revenue from service agreements is recognized ratably over the term of the
agreement. Revenue from software licensing is recognized upon performance of
milestones when collectibility is reasonably assured. Revenue from development
contracts is recognized under the percentage-of-completion method of accounting
as costs are incurred. Provisions for estimated losses on contracts are recorded
in the period when such losses are determined.

Significant Customers and Export Sales
In 1997, 1996 and 1995, net sales to one customer accounted for approximately
11%, 14% and 12%, respectively. A second customer accounted for approximately
8%, 14% and 10% of net sales in 1997, 1996, and 1995, respectively. The Company
had international sales of approximately $9,541,000, $17,355,000 and $26,884,000
in 1997, 1996, and 1995, respectively. Export sales consisted of approximately
$7,043,000, $11,698,000 and $18,548,000 for those same periods. Of these export
sales, sales into Europe were approximately $5,337,000, $8,185,000, and
$13,089,000 in 1997, 1996 and 1995, respectively. Export sales do not include
direct sales from the Company's foreign subsidiaries.

Translation of Foreign Currencies
The Company has designated the local currency as the functional currency for all
foreign locations. Accordingly, assets and liabilities of all foreign
subsidiaries are translated at year-end rates of exchange, and income statement
accounts are translated at average rates of exchange. The resulting translation
adjustments are excluded from net earnings, and accumulated as a separate
component of stockholder's equity.
     Foreign currency transaction gains and losses are included in results of
operations in the periods in which they occur, and are immaterial for all
periods presented.

Cash, Cash Equivalents, and Marketable Securities
The Company considers all highly liquid instruments purchased with a maturity of
three months or less to be cash equivalents. Marketable securities consist of
highly liquid investments with maturities of more than three months when
purchased. Investments are stated at cost, plus accrued interest, which
approximates fair market value. In addition, the Company classified all
investments as available-for-sale securities. Realized gains and losses are
determined on the specific identification method and are included in interest
income or expense. The portfolio at December 31, 1997 matures at various dates
through December 31, 1998.

<PAGE>   11

Inventories
Inventories are stated at the lower of cost or market, with cost determined
under the first-in, first-out method.

Property and Equipment
Property and equipment are stated at cost. Depreciation and amortization of
property and equipment are computed principally using the straight-line method
over the estimated useful lives of the assets as follows:

                  Machinery and equipment            1-5 years
                  Furniture and fixtures             7 years
                  Leasehold improvements             shorter of lease term
                                                     or estimated useful life.

     Maintenance and repairs are charged to expense as incurred. Upon retirement
or sale, the cost of the disposed assets and the related accumulated
depreciation are removed from the accounts and any resulting gain or loss is
credited or charged to income.

Income Taxes
Deferred tax assets and liabilities reflect the net tax effects of temporary
differences between the carrying amounts of assets and liabilities for financial
reporting purposes and the amounts used for income tax purposes. A valuation
allowance is provided for the net deferred tax assets if, based on the weighted
available evidence, it is more likely than not that some or all of the deferred
tax assets will not be realized.

Accrued Warranty
The Company provides an accrual for future warranty costs based upon the
relationship of prior years' sales to actual warranty costs which approximates
expected future warranty costs.

Research and Development
Cost incurred in the research and development of software products are expensed
as incurred until the technological feasibility of the product has been
established. After technological feasibility is established, any additional
costs would be capitalized. As the Company believes the current process for
developing software is essentially completed concurrently with the establishment
of technological feasibility, no costs have been capitalized to date.

Concentration of Credit Risk
Financial instruments, which potentially subject the Company to concentration of
credit risk, are principally cash and cash equivalents, marketable securities,
and accounts receivable. The Company places its investments in highly rated
financial institutions and, by policy, limits the amount of credit exposure to
any one financial institution.
     Concentration of credit risk with respect to accounts receivable is limited
to certain customers with whom the Company makes substantial sales. Two
customers accounted for approximately 28% and 30% of the Company's outstanding
accounts receivable at December 31, 1997 and 1996, respectively. To reduce
credit risk, the Company performs ongoing credit evaluation, account monitoring
procedures and maintains reserves for potential losses. These losses have been
within management's expectations.

Net Income (Loss) Per Common Share and Common Equivalent Share
The Company adopted the requirements of SFAS No. 128 "Earnings per Share" in 
the fourth quarter, 1997. This statement replaced the calculation of primary and
fully diluted earnings per share with basic and diluted earnings per share
(EPS). Basic EPS excludes the effect of any dilutive options, warrants or
convertible securities and is computed by dividing income available to common
stockholders by the weighted average number of common shares outstanding for the
period. Diluted EPS reflects the potential dilution that could occur if
securities or other contracts to issue common stock were exercised or converted
into common stock or resulted in the issuance of common stock that then shared
in the earnings of the entity. Diluted EPS is computed by dividing income
available to common stockholders by the sum of the weighted average number of
common shares and common share equivalents computed using the average market
price for the period under the treasury stock method. All earnings per share
amounts have been restated to conform with the SFAS 128 requirements.

The following table reconciles the numerator and the denominators of the basic
and diluted EPS computations shown on the Consolidated Statements of Operations:

<TABLE>
<CAPTION>
                                               For the years ended December 31,
- --------------------------------------------------------------------------------
(in thousands, except per share data)            1997         1996        1995
- --------------------------------------------------------------------------------
<S>                                            <C>          <C>          <C>
Basic EPS computation:
Numerator:
  Net (loss) income                            ($7,847)     ($12,014)    $ 8,220
Denominator:
  Weighted average common shares outstanding    15,301        15,630      15,416
Basic EPS                                       ($0.51)       ($0.77)      $0.53

Diluted EPS computation:
Numerator:
  Net (loss) income                            ($7,847)     ($12,014)    $ 8,220
Denominator:
  Weighted average common shares outstanding    15,301        15,630      15,416
  Stock options                                      -             -         276
                                               ---------------------------------
  Total shares                                  15,301        15,630      15,692 
Diluted EPS                                     ($0.51)       ($0.77)      $0.52
</TABLE>

Outstanding options of 1,758,605 and 1,272,009 as of December 31, 1997 and 1996,
respectively, were not included in the  diluted EPS computation because their
effect would be antidilutive. Options to purchase shares of the Company's common
stock of 69,837 for the year ended December 31,1995 were outstanding during the
period but were not included in the computation of diluted EPS because the price
of the options, which range from $7.73 to $14.00 for 1995, was greater than the
average market price of the common stock for the reported period. The
outstanding options not included in the calculation for 1995 will expire between
September 25, 2001 and October 25, 2005.



<PAGE>   12

Newly Issued Accounting Standards

The FASB has issued Statement No. 130 ("SFAS 130") "Reporting Comprehensive
Income." This Statement requires changes in comprehensive income to be shown in
a financial statement that is displayed with the same prominence as other
financial statements. While not mandating a specific financial statement format,
the Statement requires that an amount representing total comprehensive income be
reported. The Statement will become effective for fiscal years beginning after
December 15, 1997. Reclassification of financial statements for earlier periods
is required for comparative purposes. The Company does not believe that the
adoption of SFAS 130 will have a material impact on result of operations.

The FASB also issued Statement No. 131 ("SFAS 131"), "Disclosures about Segments
of an Enterprise and Related Information". This Statement, which supersedes
Statement No. 14 "Financial Reporting for Segments of a Business Enterprise,"
changes the way public companies report information about segments. The
Statement, which is based on the management approach to segment reporting,
includes requirements to report segment information quarterly and entity-wide
disclosures about products and services, major customers, and the material
countries in which the entity holds assets and reports revenues. The Statement
is effective for periods beginning after December 15, 1997. Restatement for
earlier years is required for comparative purposes unless impracticable. In
addition, SFAS 131 need not be applied to interim periods in the initial year;
however, in subsequent years, interim period information must be presented on a
comparative basis. The Company is currently evaluating this Statement and its
effect on financial statement disclosures.

Change In Presentation of Consolidated Statements of Cash Flows
During 1997 the Company changed from the direct to the indirect method of
presenting its consolidated statements of cash flows. Prior year amounts have
been reclassified to conform to the current year presentation. 

C INVESTMENTS
Investment classified as current assets were as follows:
<TABLE>
<CAPTION>
                                 1997        1996
- --------------------------------------------------
(in thousands)
- --------------------------------------------------
<S>                            <C>         <C>    
Cash equivalents:
Repurchase agreements          $ 1,260     $ 1,950 
Mutual funds                     1,674       6,750
Commercial paper                   808       2,448
- --------------------------------------------------
Total cash equivalents         $ 3,742     $11,148
- --------------------------------------------------

Marketable securities:
Fixed income securities        $ 7,074     $     -
Repurchase agreements              263           -
Certificates of deposit          1,291           -
Commercial paper                 2,557       2,918
U.S. Government securities       1,258       4,000
- --------------------------------------------------
Total marketable securities    $12,443     $ 6,918
- --------------------------------------------------
</TABLE>


<PAGE>   13
 

D. INVENTORIES
Inventories consist of:
<TABLE>
<CAPTION>
                                 December 31,
- ------------------------------------------------
(in thousands)               1997           1996
- ------------------------------------------------
<S>                        <C>            <C>   
Raw materials              $1,043         $1,373
Work in process               373            718
Finished goods              4,294          6,646
- ------------------------------------------------
Total inventories          $5,710         $8,737
- ------------------------------------------------
</TABLE>

During 1996, the Company recorded an additional inventory provision of
$2,400,000 to reflect inventory exposures as the Company transitioned from LAN
to remote access products.

E. PROPERTY AND EQUIPMENT
Property and equipment consist of:
<TABLE>
<CAPTION>
                                                       December 31,
- ----------------------------------------------------------------------
(in thousands)                                       1997         1996
- ----------------------------------------------------------------------
<S>                                                <C>         <C>    
Machinery and equipment                            $11,492     $12,083
Furniture and fixtures                                 554         572
Leasehold improvements                               1,188         970
- ----------------------------------------------------------------------
                                                    13,234      13,625
Less accumulated depreciation and amortization       9,962       9,031
- ----------------------------------------------------------------------
Property and equipment, net                        $ 3,272     $ 4,594
- ----------------------------------------------------------------------
</TABLE>

F. COMMITMENTS AND CONTINGENCIES
Letter of Credit
The Company has an outstanding letter of credit of approximately $288,000 at
December 31, 1997 and 1996. This letter of credit which matures on April 30,
2002, automatically renews annually on December 31. This letter of credit 
collateralized the Company's obligation to a third party for a certain lease
transaction. The fair value of this letter of credit is estimated to be the same
as the contract amount.

Operating Leases
The Company leases its office and manufacturing facilities under operating
leases expiring at various dates through 2002. Under certain leases the Company
is obligated to pay taxes, repairs, and other operating costs. The Company has
the option to extend the term of the lease of its primary office and
manufacturing facility for two five-year periods commencing on May 1, 2002 and
May 1, 2007. Rental expense amounted to approximately $1,128,000, $1,556,000 and
$1,666,000 in 1997, 1996 and 1995, respectively. At December 31, 1997 future
rental commitments are as follows:
<TABLE>
<CAPTION>
- ---------------------------
(in thousands)
- ---------------------------
<C>                  <C>   
1998                 $  653
1999                    543
2000                    496
2001                    476
2002                    162
Thereafter                -
- ---------------------------
Total                $2,330
</TABLE>


<PAGE>   14



G. CAPITAL STOCK
Common Stock
The Company has an Employee Stock Purchase Plan ("Purchase Plan") available to
most full time employees. Under this plan, 300,000 shares of common stock were
reserved for issuance. Eligible employees may designate not more than 5% of
their cash compensation to be deducted each pay period for the purchase of
common stock under the Purchase Plan. The purchase price of the shares under the
plan is equal to the lower of 85% of the fair market value per share of the
stock on the grant date (first day of the exercise period) or 85% of the fair
market value on the exercise date (the last day of the exercise period, the fair
market value as of a given date is determined by averaging the last sales price
of the stock for the ten trading days immediately proceeding the given date. The
Company sold 32,677 shares and 41,628 shares to employees in 1997 and 1996,
respectively, under the Purchase Plan. At December 31, 1997, 257,097 shares
remained unissued under the Purchase Plan. The weighted average fair value of
the purchase right to a share of Company stock under the Purchase Plan was
estimated to be $1.33 and $1.65 for 1997 and 1996, respectively. No compensation
cost has been recognized for shares purchased.

Preferred Stock
In 1991, the Shareholders approved the authorization of 7,500,000 shares of
preferred stock. The Board of Directors is authorized, subject to any
limitations prescribed by law, to issue from time to time such shares of
preferred stock in one or more series. Each such series of preferred stock will
have such number of shares, designations, preferences, voting power,
qualifications, and special or private rights or privileges as shall be
determined by the Board of Directors, which may include, among others, dividend
rights, voting rights, preemptive and sinking fund provisions, liquidation
preferences, conversion rights and preemptive rights. No such shares have been
issued to date.

Stock Options
The Company's stock option plans generally provide for the granting to employees
of incentive stock options to purchase shares of common stock at the fair market
value as defined by the plan on the date of grant and of non-qualified stock
options at no less than 50% of the fair market value as defined by the plan on
the date of the grant. To date the Company has never issued non-qualified stock
options at an exercise price less than the fair market value on the date of the
grant. Generally, options become exercisable at the rate of 25% at the end of
each of the first four anniversaries of the grant. Options generally expire ten
years from the date of grant, or ninety days from the date of termination of
employment. As of December 31, 1997, 4,384,000 shares of common stock were
reserved under the plans and 349,400 shares were available for grant.

     In September 1996, the Compensation Committee of the Board of Directors,
pursuant to the authority granted under the Company's 1991 Restated Stock
Option Plan, voted to allow employees of the Company holding options with
exercise prices greater than $3.625 per share to exchange those options for
substitute options having an option exercise price of $3.625 per share.  In
October 1996, 707,154 options were surrendered by employees and exchanged for
new options at the new option exercise price and vesting schedule.

     A summary of the status of the Company's stock plans as of December 31,
1997, 1996 and 1995, and changes during the years ended on those dates is
presented below:


<PAGE>   15


<TABLE>
<CAPTION>

                                     1997                    1996                     1995
                            ----------------------  -----------------------  ----------------------
                                          Weighted                 Weighted                Weighted
                                           Average                  Average                 Average
                              Number of   Exercise   Number of     Exercise   Number of    Exercise
                               Options       Price    Options         Price    Options        Price
                            ----------------------  -----------------------  ----------------------
<S>                           <C>            <C>       <C>            <C>      <C>            <C>  
Outstanding at the
beginning of the year         1,272,009      $3.34     1,237,649      $5.52    1,446,597      $5.37
Granted                       1,007,805      $2.02     1,245,726      $4.11      404,700      $6.76
Exercised                             -          -        (6,712)     $4.01     (218,875)     $4.72
Canceled                       (521,209)     $3.18    (1,204,654)     $6.23     (394,773)     $6.67
                            ------------            -------------            ------------
Outstanding                   1,758,605      $2.70     1,272,009      $3.34    1,237,649      $5.52
                            ----------------------  -----------------------  ----------------------

Options exercisable
at year end                     685,270      $3.41       522,604      $3.41      440,778      $5.44
Weighted average fair
value of options granted
during the year                              $1.34                    $2.78                   $4.70
</TABLE>

The following table summarizes information concerning outstanding options at
December 31, 1997:
<TABLE>
<CAPTION>
                                       Weighted Average          Weighted 
    Range of           Number of          Remaining               Average  
  Exercise Prices     Outstanding      Contractual Life        Exercise Price
  ---------------     ----------      -----------------        --------------
   <S>                 <C>                  <C>                      <C>  
   $0.73 - $1.10          12,300            9.58                     $0.95
   $1.45 - $1.56         248,100            9.95                     $1.45 
   $1.70 - $2.10         346,905            9.62                     $1.85 
   $2.53 - $3.63       1,130,350            8.14                     $3.18 
   $6.00 - $7.50          20,950            3.36                     $7.43
                      --------------------------------------------------------
                       1,758,605            8.64                     $2.71
                      =========================================================
</TABLE>

Pro Forma Impact of SFAS 123
SFAS 123 "Accounting for Stock-Based Compensation" requires that companies
either recognize compensation expense for grants of stock, stock options, and
other equity instruments based on fair value, or provide pro forma disclosure of
net income and earnings per share in the notes to the financial statements. The
Company adopted the disclosure provisions of SFAS 123 in 1996 and has applied
APB Opinion 25 and related interpretations in accounting for its plans. Had
compensation cost for the Company's stock-based compensation plans been
determined based on fair value at grant dates as calculated in accordance with
SFAS 123, the Company's net (loss) income and (loss) income per share for the
years ended December 31, 1997, 1996 and 1995 would have been reduced to the pro
forma amounts indicated below:

<TABLE>
<CAPTION>

                          1997                         1996                             1995
                -------------------------    -------------------------    ------------------------------------------------
                            Basic/Diluted               Basic/Diluted                       Basic             Diluted
                Net loss   loss per share    Net loss   loss per share    Net Income   Income per share   Income per share
                -------------------------    -------------------------    -------------------------------------------------
<S>              <C>            <C>           <C>             <C>            <C>             <C>              <C>
As reported      ($7,847)       ($0.51)       ($12,014)       ($0.77)         $8,220         $0.53            $0.52

Pro forma        ($8,140)       ($0.53)       ($12,627)       ($0.81)         $8,011         $0.51            $0.51
</TABLE>

The fair value of each stock option is estimated on the date of grant using the
Black-Scholes option-pricing model with the following weighted-average
assumptions: an expected life of six years, expected volatility of 75% in 1997,
and 65% in 1996 and 1995, and no dividends assumed. The weighted average
assumptions for the risk-free interest rates for 1997, 1996 and 1995 were 6.11%,
6.32% and 6.58%, respectively.             

     The effects of applying SFAS 123 in this pro forma disclosure are not
indicative of future amounts since SFAS 123 does not apply to awards prior to
1995, and additional awards in future years are anticipated.


<PAGE>   16



H. RESTRUCTURING OF OPERATIONS
During the fourth quarter of 1996, the Company's management announced a
restructuring plan for the strategic redirection of the Company. The
restructuring principally addressed the move toward the continued development of
the OpenROUTE Networks subsidiary. The strategies for this subsidiary are
designed to allow the Company to aggressively focus its efforts on the rapidly
growing Internet/Intranet connectivity marketplace. The Company is attempting to
leverage its strengths in the OpenROUTE internetworking software and its
successful line of GlobeTrotter Remote Access routers. The Company is
concentrating its efforts on gaining more market share and increasing revenue.
     As a result, the Company recorded a $3,312,000 charge for restructuring of
operations in the fourth quarter of 1996. This included a reduction in the
Company's work force of forty-two employees, or approximately 22%, accounting
for approximately $410,000 of severance costs. The Company incurred a charge of
approximately $785,000 in connection with the substantial reduction in its
occupancy requirements. In addition, the charge included approximately
$1,922,000 for disposal of fixed assets and approximately $195,000 of other
costs.
     During 1997, the Company incurred cash expenditures relating to the 1996
restructuring of approximately $495,000 for severance and payroll related costs,
approximately $672,000 as a result of reducing its occupancy costs and $253,000
in other restructuring related costs. Management has determined that all of the
Company's obligations from the 1996 and prior restructurings have been settled.
Accordingly, the Company reversed its remaining restructuring provision of
$241,000 against operating expenses in the third quarter of 1997.

<TABLE>
<CAPTION>
I. INCOME TAXES
The provision for income taxes consists of the following:
                                                              December 31,
- -------------------------------------------------------------------------------
(in thousands)                                           1997     1996     1995
- -------------------------------------------------------------------------------
<S>                                                      <C>      <C>      <C>
Federal - current                                        $  -     ($65)    $319
State - current                                            28       10       57
Foreign - current                                         156      215      112
- -------------------------------------------------------------------------------
Total                                                    $184     $160     $488
- -------------------------------------------------------------------------------
</TABLE>

Reconciliation between the Company's effective tax rate and the U.S. statutory
is as follows:
<TABLE>
<CAPTION>
- ----------------------------------------------------------------------
December 31,                               1997        1996      1995
- ----------------------------------------------------------------------
<S>                                        <C>        <C>        <C>
U.S. statutory rate                        (34.0%)    (34.0%)    34.0%
Foreign tax rate differential                2.4        0.1      (2.8)
Change in federal valuation allowance       34.0       35.2     (26.1)
State income taxes, net of U.S.
 Federal income tax effect                     -          -       0.5
- ----------------------------------------------------------------------
Effective tax rate                           2.4%       1.3%      5.6%
- ----------------------------------------------------------------------
</TABLE>

A valuation allowance of  $13,210,000 and $9,982,000 for 1997 and 1996
respectively has been recorded to offset the related net deferred tax assets due
to the uncertainty of realizing the benefit of these assets. The following is a
summary of the significant components of the Company's deferred tax assets and
liabilities as of December 31, 1997 and 1996:

<TABLE>
<CAPTION>

- ---------------------------------------------------------
(in thousands)                              1997     1996
- ---------------------------------------------------------
<S>                                     <C>        <C>
Deferred tax assets:
 Bad debt reserve                          $360     $   -
 Restructuring charge                         -       644
 Inventory reserves                         533       884
 Product warranty                           262       417
 Federal tax benefit of
  net operating loss carryforwards        7,889     3,878
 State tax benefit of
  net operating loss carryforwards        1,827     1,286
 Tax credit carryforwards                   912       912
 Alternative minimum tax credit             699       542
 Depreciation                               144         -
 Other items                                584       919
- ---------------------------------------------------------
Total deferred tax assets                13,210     9,482
Valuation allowance for 
 deferred tax assets                    (13,210)   (9,112)
- ---------------------------------------------------------
Net deferred assets                           -       370
Deferred tax liability:
 Depreciation                                         370
- ---------------------------------------------------------
Net deferred tax asset                       $0        $0
- ---------------------------------------------------------
</TABLE>

As of December 31, 1997 the Company had net operating loss forwards of
approximately $23,000,000 and $38,000,000 for federal and state income tax
purposes, respectively.  The federal net operating losses begin to expire in
2010 and state net operating losses begin to expire in 1998. Similarly,
research and development credit carryforwards of approximately $912,000
were available on December 31, 1997, expiring at various dates through 2005.
<PAGE>   17

J.  RETIREMENT SAVINGS PLAN
The Company has a retirement savings plan for its employees, which has been
qualified under Section 401(k) of the Code. Eligible employees are permitted to
contribute to the 401 (k) Plan through payroll deductions within statutory
limitations and subject to any limitations included in the 401 (k) Plan. The
Plan provides for the matching contribution by the Company in an annual amount
approximating 2% of a participant's compensation. The Company contributed
approximately $128,000, $185,000, and $165,000 to the plan in 1997, 1996, and
1995, respectively.

K. QUARTERLY FINANCIAL DATA
                           
                                                                    (unaudited)
                           
Selected quarterly financial data for the years ended December 31, 1997 and 1996
is as follows:
<TABLE>
<CAPTION>

- --------------------------------------------------------------------------------------------
                                                                               Basic/diluted
                                                                                  Net income
                                                  Net        Gross   Net income       (loss)
(in thousands, except per share amounts)        sales       profit       (loss)    per share
- --------------------------------------------------------------------------------------------
1997
<S>                                           <C>          <C>        <C>            <C>    
First Quarter                                  $9,125       $4,256       ($313)      ($0.02)
Second Quarter                                  7,748        3,748      (1,133)       (0.07)
Third Quarter                                   5,006        1,754      (2,894)       (0.19)
Fourth Quarter                                  5,065        1,846      (3,507)       (0.23)
- --------------------------------------------------------------------------------------------
Total                                         $26,944      $11,604     ($7,847)      ($0.51)
============================================================================================
                                     
1996                                 
First Quarter                                 $14,018       $7,231        $141        $0.01
Second Quarter                                 10,646        4,932      (2,345)       (0.15)
Third Quarter                                  10,589        5,119      (1,763)       (0.11)
Fourth Quarter                                 10,043        2,344      (8,047)       (0.52)
- --------------------------------------------------------------------------------------------
- --------------------------------------------------------------------------------------------
Total                                         $45,296      $19,626    ($12,014)      ($0.77)
- --------------------------------------------------------------------------------------------
</TABLE>                 

The 1997 fourth quarter operating loss reflects approximately $880,000 or $0.06
per share of certain adjustments and accruals relating to business operations
in the Asia-Pacific region, as well as certain employee incentive programs.
<PAGE>   18

REPORT OF INDEPENDENT ACCOUNTANTS

To the Board of Directors
and Stockholders of Proteon, Inc.:

We have audited the accompanying consolidated balance sheets of Proteon, Inc.
as of December 31, 1997 and 1996, and the related consolidated statements of
operations, stockholders' equity and cash flows for each of the three years in
the period ended December 31, 1997.  These financial statements are the
responsibility of the Company's management.  Our responsibility is to express
an opinion on these financial statements based on our audits.

     We conducted our audits in accordance with generally accepted auditing
standards.  Those standards require that we plan and perform the audit to
obtain reasonable assurance about whether the financial statements are free of
material misstatement.  An audit includes examining, on a test basis, evidence
supporting the amounts and disclosures in the financial statements.  An audit
also includes assessing the accounting principles used and significant
estimates made by management, as well as evaluating the overall financial
statement presentation.  We believe that our audits provide a reasonable
basis for our opinion.

     In our opinion, the financial statements referred to above present fairly,
in all material respects, the consolidated financial position of Proteon, Inc.
as of December 31, 1997 and 1996 and the consolidated results of its operations
and its cash flows for each of the three years in the period ended December 31,
1997 in conformity with generally accepted accounting principles.


                                             /s/ COOPERS & LYBRAND L.L.P.
                                             ----------------------------
Coopers & Lybrand, L.L.P.
Boston, Massachusetts
February 11, 1998

<PAGE>   19


- -------------------------
  STOCK PRICE HISTORY
- -------------------------


The following table sets forth the high and low sales prices of the Company's
Common Stock as reported on the NASDAQ Stock Market from January 1, 1996 to
December 31, 1997. As of December 31, 1997, the Company had approximately 507
stockholders of record. The Company has paid no dividends on its Common Stock
and anticipates it will reinvest any earnings to finance future growth.
<TABLE>
<CAPTION>

For year ended December 31, 1997                High               Low
- -----------------------------------------------------------------------
<S>                                            <C>              <C>
First Quarter                                  3 11/16           1 5/16
Second Quarter                                 2 15/16           1 7/16
Third Quarter                                   2 1/2            1 9/16
Fourth Quarter                                  3 1/2            1 1/32


For year ended December 31, 1996                High               Low
- -----------------------------------------------------------------------
First Quarter                                   7 1/2             4 3/4
Second Quarter                                  6 1/2             3 5/8
Third Quarter                                   4 1/4             2 3/8
Fourth Quarter                                  4 1/4            2 1/16
</TABLE>


<PAGE>   1
                                                
                                                                    EXHIBIT 21
                                                                    ----------

Proteon, Inc.
Subsidiaries of the registrant:

I.    Proteon International Ltd.
      Lockington Hall
      Derby  DE74 2RH
      England
      Organized under the laws of England

II.   Proteon International SARL
      2000 route des Lucioles
      Les Algorithmes
      Bat Aristote  A-BP 29
      Sophia Antipolis  06901
      France
      Organized under the laws of France

III.  Proteon International GMBH
      Falkensteiner Strasse 11
      Kelkheim D 65779
      Germany
      Incorporated under the laws of Germany

IV.   Proteon Networks PTE Ltd.
      30 Bideford Road #02-02
      Thongsia Building
      Singapore  229922
      Organized under the laws of Singapore

V.    OpenROUTE Networks, Inc.
      Nine Technology Drive
      Westborough, Massachusetts  01581-1799
      USA
      Incorporated in the state of Delaware

VI.   Proteon Securities Corporation
      Nine Technology Drive
      Westborough, Massachusetts  01581-1799
      USA
      Incorporated in the Commonwealth of Massachusetts

VII.  Proteon Federal Systems, Inc. (Inactive)
      Nine Techology Drive
      Westborough, Massachusetts  01581-1799
      USA
      Incorporated in the Commonwealth of Massachusetts

VIII. Proteon FSC, Inc.
      55-11 Curaco Gade
      Charlotte Amalie
      Virgin Islands  00803
      Incorporated in the U.S. Virgin Islands

IX.   Proteon Australia PTY
      80 Mount Street
      Level 8
      North Sydney  NSW 2060
      Australia
      Organized under the laws of Australia




<PAGE>   1
                                                                      EXHIBIT 23


                       CONSENT OF INDEPENDENT ACCOUNTANTS

We consent to the incorporation by reference in the registration statement of
Proteon, Inc. on Forms S-8 (File No. 33-85524 and File No. 333-31055) of our
reports dated February 11, 1998, on our audits of the consolidated financial
statements and financial statement schedule of Proteon, Inc. as of December 31,
1997 and 1996, and for the three years ended December 31, 1997 which reports are
included or incorporated by reference in this Annual Report on Form 10-K.


                                             /s/ COOPERS & LYBRAND L.L.P.

Boston, Massachusetts
March 30, 1998

<TABLE> <S> <C>

<ARTICLE> 5
<MULTIPLIER> 1,000
<CURRENCY> U.S DOLLARS
       
<S>                             <C>                     <C>                     <C>
<PERIOD-TYPE>                   YEAR                   YEAR                   YEAR
<FISCAL-YEAR-END>                          DEC-31-1995             DEC-31-1996             DEC-31-1997
<PERIOD-START>                             JAN-01-1995             JAN-01-1996             JAN-01-1997
<PERIOD-END>                               DEC-31-1995             DEC-31-1996             DEC-31-1997
<EXCHANGE-RATE>                                      1                       1                       1
<CASH>                                          25,829                  16,612                   5,317
<SECURITIES>                                     6,863                   6,918                  12,443
<RECEIVABLES>                                   12,138                   7,625                   6,224
<ALLOWANCES>                                         0                       0                       0
<INVENTORY>                                      4,425                   8,737                   5,710
<CURRENT-ASSETS>                                50,712                  40,977                  30,131
<PP&E>                                          31,875                  13,625                  13,234
<DEPRECIATION>                                  23,558                   9,031                   9,962
<TOTAL-ASSETS>                                  59,029                  45,571                  33,403
<CURRENT-LIABILITIES>                           11,706                  10,380                   6,511
<BONDS>                                              0                       0                       0
                           49,141                  49,292                  49,347
                                          0                       0                       0
<COMMON>                                             0                       0                       0
<OTHER-SE>                                     (1,818)                (14,101)                (22,455)
<TOTAL-LIABILITY-AND-EQUITY>                    59,029                  45,571                  33,403
<SALES>                                         51,810                  32,175                  22,248
<TOTAL-REVENUES>                                75,323                  45,296                  26,944
<CGS>                                           27,373                  20,825                  12,722
<TOTAL-COSTS>                                   36,664                  25,670                  15,340
<OTHER-EXPENSES>                                31,388                  32,741                  20,319
<LOSS-PROVISION>                                     0                       0                       0
<INTEREST-EXPENSE>                             (1,437)                 (1,261)                 (1,052)
<INCOME-PRETAX>                                  8,708                (11,854)                 (7,663)
<INCOME-TAX>                                       488                     160                     184
<INCOME-CONTINUING>                              8,220                (12,014)                 (7,847)
<DISCONTINUED>                                       0                       0                       0
<EXTRAORDINARY>                                      0                       0                       0
<CHANGES>                                            0                       0                       0
<NET-INCOME>                                     8,220                (12,014)                 (7,847)
<EPS-PRIMARY>                                     0.53                  (0.77)                  (0.51)
<EPS-DILUTED>                                     0.52                  (0.77)                  (0.51)
        

</TABLE>


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