OSTEOTECH INC
DEF 14A, 1998-04-30
MISC HEALTH & ALLIED SERVICES, NEC
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                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934
                                (Amendment No. )

Filed by the Registrant |X|
Filed by a Party other than the Registrant |_|

Check the appropriate box:

|_| Preliminary Proxy Statement
|_| Confidential, for Use of the Commission Only (as permitted by
    Rule 14a-6(e)(2))
|X| Definitive Proxy Statement
|_| Definitive Additional Materials
|_| Soliciting Material Pursuant to ss. 240.14a-11(c) or ss. 240.14a-12


                                 Osteotech, Inc.
                (Name of Registrant as Specified In Its Charter)

                             KEVIN T. COLLINS, ESQ.
                   (Name of Person(s) Filing Proxy Statement)

Payment of Filing Fee (Check the appropriate box):

|X| No Fee required

|_| Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

1) Title of each class of securities to which transaction applies:

   _____________________________________________________________________________

2) Aggregate number of securities to which transaction applies:

   _____________________________________________________________________________

3) Per unit price or other underlying value of transaction  computed  pursuant
   to  Exchange  Act Rule 0-11 (Set forth the amount on which the filing fee is
   calculated and state how it was determined)

   _____________________________________________________________________________

4) Proposed maximum aggregate value of transaction:

   _____________________________________________________________________________

5) Total fee paid:

   _____________________________________________________________________________

|_| Fee paid previously with preliminary materials

|_| Check box if any part of the fee is offset as provided by
    Exchange Act Rule 0-11(a)(2) and identify the filing for which
    the offsetting fee was paid previously.  Identify the previous
    filing by registration statement number, or the form or schedule
    and the date of its filing.

    1) Amount Previously Paid: _________________________________________________

    2) Form, Schedule or Registration Statement No. ____________________________

    3) Filing Party: ___________________________________________________________

    4) Date Filed: _____________________________________________________________


<PAGE>



                              [OSTEOTECH INC. LOGO]

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

To our Stockholders:

     The annual  meeting of  stockholders  (the "Annual  Meeting") of Osteotech,
Inc., a Delaware corporation  ("Osteotech" or the "Company") will be held at the
Sheraton   Eatontown  Hotel  and  Conference  Center,  6  Industrial  Way  East,
Eatontown,  New Jersey 07724 on Thursday,  June 4, 1998 at 9:00 A.M. local time,
for the following purposes:

     1.   To elect six directors (Proposal No. 1);

     2.   To approve an amendment to the  Company's  1991 Stock Option Plan,  as
          amended  (the "Plan") to increase the number of shares of Common Stock
          reserved  for issuance  under the Plan by 818,624  shares to 2,813,765
          shares (Proposal No. 2);

     3.   To approve an amendment to the Plan to conform the Plan to the current
          provisions  of Rule 16b-3 under the  Securities  Exchange  Act of 1934
          (Proposal No. 3);

     4.   To ratify the selection of Coopers & Lybrand  L.L.P.  as the Company's
          independent  auditors  for the fiscal  year ending  December  31, 1998
          (Proposal No. 4); and

     5.   To transact such other business as may properly come before the Annual
          Meeting.

     Only  stockholders  of record of the  Company at the close of  business  on
April 24, 1998 are entitled to notice of and to vote at the Annual Meeting.





<PAGE>

     Osteotech  hopes that as many  stockholders  as  possible  will  personally
attend the Annual Meeting. Whether or not you plan to attend the Annual Meeting,
please complete the enclosed proxy card and sign, date and return it promptly so
that your shares will be represented. Sending in your proxy will not prevent you
from voting in person at the Annual Meeting.

                                            By Order of the Board of Directors,



                                            MICHAEL J. JEFFRIES
                                            Secretary

Eatontown, New Jersey
May 4, 1998











           51 James Way o Eatontown, New Jersey 07724 o (732) 542-2800

                                        2

<PAGE>

                              [OSTEOTECH INC. LOGO]


                                 PROXY STATEMENT

     This Proxy  Statement is furnished in connection  with the  solicitation of
proxies for use at the annual meeting of stockholders  (the "Annual Meeting") of
Osteotech,  Inc., a Delaware  corporation  ("Osteotech"  or the "Company") to be
held at the Sheraton  Eatontown  Hotel and Conference  Center,  6 Industrial Way
East, Eatontown, New Jersey 07724, at 9:00 A.M. local time, on Thursday, June 4,
1998 and at any adjournments thereof.

     The  accompanying  proxy is  solicited  by the  Board of  Directors  of the
Company (the "Board") and is revocable by the  stockholder at any time before it
is voted. For more information  concerning the procedure for revoking the proxy,
see "General."

     This Proxy  Statement was first mailed to stockholders of the Company on or
about  May  4,  1998,  accompanied  by  the  Company's  1997  Annual  Report  to
Stockholders.  The principal  executive offices of the Company are located at 51
James Way, Eatontown, New Jersey 07724, telephone (732) 542-2800.

                      OUTSTANDING SHARES AND VOTING RIGHTS

     Only stockholders of the Company at the close of business on April 24, 1998
(the  "Record  Date") are  entitled to receive  notice of and vote at the Annual
Meeting.  As of the  Record  Date,  the  number  and  classes of stock that were
outstanding and will be entitled to vote at the meeting were 8,859,553 shares of
Common Stock, $.01 par value (the "Common Stock" or each a "Common Share"). Each
Common  Share  is  entitled  to one  vote on all  matters.  No  other  class  of
securities  will be  entitled  to  vote  at the  Annual  Meeting.  There  are no
cumulative voting rights.

     To be elected,  a director  must  receive a  plurality  of the votes of the
shares  present  in person or  represented  by proxy at the Annual  Meeting  and
entitled to vote on the election of directors, provided that a quorum is present
(Proposal  No. 1).  The  affirmative  vote of at least a majority  of the Common
Shares present in person or by proxy and entitled to vote at the Annual Meeting,
provided  that a quorum is present,  is  necessary  for the approval of Proposal
Nos. 2, 3 and 4. The Company's bylaws provide that a quorum is representation in
person or by proxy at the Annual Meeting of at least one-third of the issued and
outstanding shares entitled to vote as of the Record Date.

     Pursuant to the Delaware  General  Corporation Law, only votes cast "For" a
matter constitute  affirmative votes. Further, under Delaware law, proxies which
are voted by marking  "Withheld" or "Abstain" on a particular matter are counted
for


                                       1

<PAGE>

quorum  purposes,  but since they are not cast "For" a particular  matter,  they
will have the same effect as  negative  votes or votes  "Against"  a  particular
matter.  If a  validly  executed  proxy is not  marked to  indicate  a vote on a
particular  matter and the proxy  granted  thereby is not  revoked  before it is
voted,  it will be voted "For" such matter.  Where brokers are  prohibited  from
exercising  discretionary  authority for beneficial owners who have not provided
voting instructions  (commonly referred to as "broker  non-votes"),  such broker
non-votes will be treated as shares that are present for purposes of determining
the  presence of a quorum,  but will be treated as not  present for  purposes of
determining  the  outcome  of any  matter as to which the  broker  does not have
authority to vote.

                     PROPOSAL NO. 1 - ELECTION OF DIRECTORS

     The  current  provisions  of the  Company's  bylaws  authorize  up to seven
directors  or  such  other  number  as  shall  be  determined  by the  Board  as
constituting the full Board. Pursuant to a resolution of the Board, the Board is
composed  currently of six  directors.  The Board has nominated six nominees for
election  to the Board at the Annual  Meeting  pursuant to a  resolution  of the
Board adopted on March 26, 1998. Proxies cannot be voted for a greater number of
persons  than the number of  nominees  named.  The  Company's  bylaws  currently
provide that all of the  directors  are elected to serve until their  successors
are elected and qualified, or until their earlier death, resignation or removal.

     The  nominees  for  election  to  the  office  of  director,   and  certain
information with respect to their ages and backgrounds,  are set forth below. It
is the  intention  of  the  persons  named  in the  accompanying  proxy,  unless
otherwise  instructed,  to vote to elect the nominees named herein as directors.
If any nominee declines to serve or becomes  unavailable for any reason, or if a
vacancy should occur before the election (although management knows of no reason
to  anticipate  that  this  will  occur),  the  proxies  may be  voted  for such
substitute nominees as management may designate.



                                       2
<PAGE>

Nominees for Election to the Office of Director at the Annual Meeting.

<TABLE>
<CAPTION>
                                                   Current Position                        Director of
Name                                   Age         with Company                           Company Since
- -------------------------------------------------------------------------------------------------------
<S>                                     <C>        <C>                                         <C> 
Donald D. Johnston(1)(2)(3)             73         Chairman of the Board                       1991

Richard W. Bauer(1)                     53         President, Chief Executive Officer and      1994
                                                     Director

Michael J. Jeffries                     55         Executive Vice President,                   1991
                                                     Chief Operating Officer,
                                                     Chief Financial Officer, Secretary and
                                                     Director

Kenneth P. Fallon, III(3)               59         Director                                    1995

Stephen J. Sogin, Ph.D.(1)(2)(3)        56         Director                                    1988

John Phillip Kostuik, M.D., FRCS(C)(2)  60         Director                                    1997
</TABLE>
- ----------
(1)    Member of Executive Committee
(2)    Member of Audit Committee
(3)    Member of Compensation Committee

                  BUSINESS EXPERIENCE OF NOMINEES TO THE BOARD

     Donald D.  Johnston,  has been a director  of the Company  since  September
1991. Mr. Johnston became Chairman of the Board in June 1992. Over the course of
25 years Mr. Johnston held various positions of increasing  responsibility  with
Johnson  &  Johnson,  Inc.  At the time of his  retirement  in May 1986 he was a
member of the  executive  committee  and the  board of  directors  of  Johnson &
Johnson,  Inc.  Mr.  Johnston is a director of Human Genome  Sciences,  Inc. and
serves  on  the  boards  of two  private  companies.  It is  expected  that  Mr.
Johnston's directorship at Human Genome Sciences, Inc. will terminate on May 20,
1998, as Mr. Johnston does not plan to stand for re-election. Mr. Johnston has a
B.A. in economics from the University of Cincinnati.

     Richard W. Bauer,  joined  Osteotech in February 1994 as  President,  Chief
Executive Officer and a member of the Board. Prior to joining the Company,  from
1992 to 1993,  Mr. Bauer was  President of the  Prosthetic  Implant  Division of
Zimmer,  Inc., a subsidiary of Bristol-Myers  Squibb Company.  From 1991 through
1992, Mr. Bauer served as Senior Vice President and General  Manager of Zimmer's
Fracture  Management  Division  and  as  Vice  President  of  Marketing  of  its
Orthopaedic  Implant Division from 1989 to 1991. Mr. Bauer previously  served in
positions of significant  responsibility  with  Professional  Medical  Products,
Inc.,  Support  Systems  International,  Inc. and the Patient  Care  Division of
Johnson &


                                       3

<PAGE>

Johnson,  Inc. Mr. Bauer has B.S. and M.B.A.  degrees from  Fairleigh  Dickinson
University.

     Michael J. Jeffries,  Executive Vice President,  Chief  Operating  Officer,
Chief  Financial  Officer and  Secretary,  has been with Osteotech for more than
eight years.  He joined  Osteotech in January  1990,  originally  as Senior Vice
President  and  Chief  Financial  Officer,  became  Secretary  in May 1991 and a
director in July 1991,  was appointed  Executive  Vice President in October 1992
and Chief Operating  Officer in January 1994. Prior to joining the Company,  Mr.
Jeffries had more than 25 years of business  experience in various  positions of
increasing  responsibility in a number of publicly and privately held companies,
in some of which he was also a member of the board of  directors.  Mr.  Jeffries
has a B.B.A.  degree  from the City  College of New York and a M.B.A.  degree in
finance from Fordham University.

     Kenneth P. Fallon,  III, was elected to serve on the Board in 1995 and is a
consultant to the medical device industry.  In 1997, Mr. Fallon was President of
the surgical business at Haemonetics  Corporation.  In 1994 and 1995, Mr. Fallon
served as Chief  Executive  Officer  and  Chairman  of the Board of  UltraCision
Incorporated, a manufacturer of advanced technology medical devices. UltraCision
was sold to Ethicon EndoSurgery,  a unit of Johnson & Johnson, Inc., in November
1995. From 1992 through 1994, Mr. Fallon served as President and Chief Executive
Officer of American Surgical Technologies Corporation. Mr. Fallon was President,
U.S.  Operations of Zimmer,  Inc., a subsidiary of Bristol-Myers  Squibb Company
from 1991 to 1992.  From 1985  through  1991,  he also  served as  President  of
Zimmer's  Orthopaedic  Implant  Division  and  from  1983 to  1985,  as its Vice
President of Marketing. Mr. Fallon previously served in positions of significant
responsibility  with the Codman and  Orthopedic  Divisions of Johnson & Johnson,
Inc.  Mr.  Fallon  has a B.B.A.  degree  in  marketing  from the  University  of
Massachusetts and a M.B.A. degree from Northeastern University.

     Stephen J. Sogin,  Ph.D.,  has served as a director  of the  Company  since
October  1988.  From  December  1984 until  January  1, 1995,  he was a founding
general partner of Montgomery Medical Ventures.  Dr. Sogin currently serves as a
venture  capital  consultant  and  serves  on the  board of  directors  of Finet
Holdings Corp. He has a B.S., M.S. and Ph.D. in microbiology from the University
of Illinois.  On July 1, 1997,  Dr. Sogin  consented to a cease and desist order
issued by the  Securities and Exchange  Commission  involving his late filing of
Forms 3, 4 and 5 which he was  required  to file in his  capacity  as a  general
partner of Montgomery  Medical  Ventures II. None of the  Commission's  findings
involve charges that Dr. Sogin received improper gains or personal benefits as a
result of these violations. Dr. Sogin has advised the Company that the trades in
question were conducted by the partnership  (Montgomery Medical Ventures II) and
none of these trades were executed on his behalf personally.

                                       4

<PAGE>

     John Phillip Kostuik,  M.D., FRCS(C),  was elected to serve on the Board in
1997.  Dr. Kostuik is currently and has since 1991 been a Professor and Chairman
of the Department of Orthopaedic  Surgery,  Johns Hopkins University,  School of
Medicine,  Chief  Spine  Division.  He is the past  president  of the  Scoliosis
Research Society and the North American Spine Society and he currently serves on
the  executive  committee of the North  American  Spine  Society.  He has a B.A.
degree from Queens  University in Kingston,  Ontario,  graduating in 1957, and a
M.D. degree from Queens University, graduating in 1961.

     The Board of  Directors  recommends  a vote FOR the election of each of the
nominees named above. (Proposal No. 1 on the Proxy).

             INFORMATION CONCERNING DIRECTORS AND EXECUTIVE OFFICERS

Directors' Cash Compensation

     Members of the Board who are not executive  officers of the Company receive
$15,000 per annum in  consideration  of their serving on the Board. The Chairman
of the Board  receives  an  additional  $10,000  per annum.  Each  Board  member
receives  $1,000 for each Board meeting  attended in excess of four per year and
reimbursement  for travel and related  expenses  incurred in connection with his
attendance  at  meetings.   Members  of  the  Board  do  not  receive   separate
compensation  for  acting as  members of  Committees  of the  Board,  other than
reimbursement  for travel and related expenses incurred in connection with their
attendance at meetings.  Directors who also serve as executive  officers receive
cash  compensation  solely for acting in such capacity as an executive  officer.
See "Summary Compensation Table."

Directors' Stock Options

     During the year ended  December 31, 1997,  the Company  granted  options to
purchase  Common Stock under the Company's  1991  Independent  Directors'  Stock
Option  Plan,  exercisable  at a price  equal  to the fair  market  value of the
Company's Common Stock on the date of grant, as follows:



                                       5

<PAGE>

                                             Number of
Name                                        Options(1)            Exercise Price
- --------------------------------------------------------------------------------
Kenneth P. Fallon, III....................    10,000                  $9.50
Donald D. Johnston........................    10,000                   9.50
John Phillip Kostuik, M.D., FRCS(C).......    20,000                   9.50
Stephen J. Sogin, Ph.D.(2)................    10,000                   9.50

- ----------
(1)  The options  listed here vest at the rate of 25% per annum  during the four
     (4) year period  commencing on the first  anniversary  of the date of grant
     and expire five (5) years from the date of vesting.  Options  granted after
     July 1,  1997  will  become  exercisable  in  their  entirety  one (1) year
     following the date of grant and will expire on the tenth anniversary of the
     date of grant.

(2)  Dr.  Sogin also  received an option to  purchase  20,000  shares  under the
     Company's  1991 Stock Option Plan, as amended (the "Plan"),  for consulting
     services rendered. See "Certain Relationships and Related Transactions."

Section 16(a) Beneficial Ownership Reporting Compliance

     Ownership of and  transactions in the Company's  securities by officers and
directors of the Company and  beneficial  owners of 10% or more of the Company's
outstanding  Common  Stock are  required to be reported  to the  Securities  and
Exchange  Commission  pursuant to Section 16(a) of the Exchange Act.  Except for
the late filings  described  below,  for the year ended December 31, 1997 all of
the required  filings by the foregoing  persons were made on a timely basis. One
Form 4 reporting three  transactions  filed by Kenneth P. Fallon, III on January
30, 1998 and one Form 4 reporting four transactions filed by Michael J. Jeffries
on January 22, 1998, were approximately  three weeks and one and one-half months
late, respectively.  The Company has been advised by Dr. Stephen J. Sogin of the
following  late  filings  made by Dr.  Sogin in years prior to 1997:  One Form 4
reporting three  transactions filed by Dr. Sogin on March 23, 1993, and one Form
4 reporting one transaction filed by Dr. Sogin on February 16, 1995 were one and
one-half months and one week late,  respectively.  The transactions  reported on
Dr.  Sogin's  reports  were  effected  by  Montgomery  Medical  Ventures  II,  a
partnership for which Dr. Sogin acted as general partner.

               INFORMATION CONCERNING BOARD AND COMMITTEE MEETINGS

     Five  meetings  of the  Company's  Board  were held  during  the year ended
December 31, 1997.  No incumbent  director  failed to attend at least 75% of the
total number of meetings of the Board and any  Committees  of the Board of which
he was a member,  held  during  the  period in such year  during  which he was a
director or a member of any such Committee, as the case may be.



                                       6

<PAGE>

                 INFORMATION CONCERNING COMMITTEES OF THE BOARD

     The only  Committees  of the Company's  Board are the Executive  Committee,
Audit Committee and Compensation Committee.

     The Executive Committee is comprised of Messrs.  Johnston and Bauer and Dr.
Sogin and is responsible for all matters arising between regular meetings of the
Board,  which would  otherwise  come before the Board,  as permitted by Delaware
law. The Executive Committee held one meeting during the year ended December 31,
1997.

     The Audit  Committee  is  comprised of Mr.  Johnston,  Dr.  Kostuik and Dr.
Sogin. The primary function of the Audit Committee is to meet with the Company's
independent  auditors to discuss and review audit  procedures  and issues,  meet
with  management  on  matters  concerning  the  Company's  financial  condition,
internal  controls  and  year-end  audit  and  report  to the  Board  on  issues
concerning  the  Company's  financial  condition and year-end  audit.  The Audit
Committee held two meetings during the year ended December 31, 1997.

     The Compensation Committee is comprised of Messrs.  Johnston and Fallon and
Dr. Sogin. The primary  function of the  Compensation  Committee is to determine
the  compensation  and  benefits of  directors  and all levels of  officers  and
employees of the Company and  administer the issuance of stock options under the
Plan.  There were three meetings of the  Compensation  Committee during the year
ended December 31, 1997.

                    BUSINESS EXPERIENCE OF EXECUTIVE OFFICERS

     The following is a description of the background of the executive  officers
of the Company who are not directors:

     James L. Russell, Ph.D., 47, joined Osteotech in December 1995 as Executive
Vice President and Chief  Scientific  Officer.  He previously  held research and
development  positions of increasing  responsibility for 16 years with Proctor &
Gamble  Company  ("P&G")  where,  in his most  recent  position  as  Director of
Research,  Pharmaceutical  Division,  Dr.  Russell  oversaw the  development  of
several  products,  including  bone-related  therapeutic  agents.  In his  prior
position  at  P&G  as  the   Pharmaceutical   Division's   Director  of  Product
Development,  he  led  the  efforts  to  develop  osteoporosis  drugs  including
Didronel(R), which is currently marketed in over 15 countries. Dr. Russell holds
a B.S. in Biology from Boston State College and a Ph.D.  in Cellular  Immunology
from Purdue University.

     Richard Russo, 49, joined the Company in September 1991, and as of April 1,
1998, was elected  Executive  Vice  President,  Strategic  Planning and Business



                                       7

<PAGE>

Development. In his new position, Mr. Russo will continue to have responsibility
for regulatory  affairs.  Mr. Russo had been promoted to Senior Vice  President,
Strategic  Planning and Business  Development in October 1995, and prior thereto
had held a number of progressively  more  responsible  positions in the areas of
marketing, business development, clinical research and regulatory affairs. Prior
to joining the Company,  Mr. Russo worked for several leading public  healthcare
firms  having  positions  of  responsibility  in  marketing,   sales,   business
development,  regulatory  affairs and clinical  research  management.  Mr. Russo
earned a B.A. in philosophy  from Boston College and an M.B.A. in marketing from
Columbia University.

     Roger C. Stikeleather,  48, joined the Company in February 1988 as National
Sales Manager,  and was appointed Vice President of Sales and Marketing in March
1989, Senior Vice President of Sales and Marketing in October 1992 and Executive
Vice  President of Sales and Marketing and Client  Relations in June 1993.  From
1976 until  joining the Company,  he held  managerial  positions  of  increasing
responsibility  with a  division  of  Johnson &  Johnson,  Inc.  During his last
assignment at Johnson & Johnson,  Inc., he served on the management  board which
organized and directed a start-up division, Extended Care Products, where he was
responsible for the national scale-up of field sales, sales management, national
contracting and nursing support  organizations.  Mr.  Stikeleather has a B.S. in
business administration from the University of North Carolina at Chapel Hill.

                           SUMMARY COMPENSATION TABLE

     The  following  table  provides a summary of  compensation  for each of the
Company's  last three fiscal years ended  December 31, 1997,  1996 and 1995 with
respect to the person serving as Osteotech's  Chief Executive Officer during the
year  ended  December  31,  1997  and  each of  Osteotech's  other  most  highly
compensated  executive officers who were serving in that capacity as of December
31, 1997  (collectively  the "Named Officers") and whose annual salary and bonus
during the year ended December 31, 1997 exceeded $100,000.



                                       8

<PAGE>

<TABLE>
<CAPTION>
                                                                                                          Long-Term
                                                                                                         Compensation
                                                                  Annual Compensation                       Awards
                                                  ----------------------------------------------------------------------------------
                                                                                            Other
                                                                                            Annual        Securities      All Other
Name and                                                                                Compensation      Underlying    Compensation
Principal Position                                Year      Salary ($)     Bonus($)         ($)(1)        Options(#)       ($)(2)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                                               <C>       <C>           <C>             <C>             <C>             <C>     
Richard W. Bauer                                  1997      $280,000      $153,195                0       176,833         $2,375
President and Chief                               1996       265,000       120,000                0       125,000(3)       2,375
   Executive Officer                              1995       250,000        60,800        $59,315(4)       20,000          2,310

Michael J. Jeffries                               1997      $194,000      $ 84,118                0        87,325         $2,375
   Executive Vice President,                      1996       182,000        64,988                0        17,500          2,375
   Chief Operating Officer                        1995       172,000        36,256(5)             0        35,800(6)       2,310
   and Chief Financial Officer

James L Russell, Ph.D.                            1997      $174,756      $ 61,411                0        43,662              0
   Executive Vice President,                      1996       165,000        47,438        $23,403(4)       15,000              0
   Chief Scientific Officer                       1995         6,875             0                0        75,000              0

Roger C. Stikeleather                             1997      $166,905      $ 58,651                0        50,212         $2,375
   Executive Vice President,                      1996       157,500        45,282                0        15,000          2,375
   Sales and Marketing                            1995       150,000        27,800(7)             0        28,635(8)       2,310
</TABLE>

- ----------
(1)  Excludes  perquisites and other personal  benefits that in the aggregate do
     not exceed 10% of the Named Officer's total annual salary and bonus.

(2)  Consists of annual Company contributions to a 401(k) plan.

(3)  Includes  an  option to  purchase  100,000  shares  of  Common  Stock at an
     exercise  price of $10.00 per share.  The fair  market  value of the Common
     Stock on the date of grant was $6.00.

(4)  Consists of relocation assistance.

(5)  The  1995  bonus  includes  $7,500  deferred  from a bonus  awarded  to Mr.
     Jeffries in 1993.

(6)  Includes an option for the purchase of 20,800 shares of Common Stock issued
     pursuant to a stock option exchange program in 1995.

(7)  The  1995  bonus  includes  $5,000  deferred  from a bonus  awarded  to Mr.
     Stikeleather in 1993.

(8)  Includes an option for the purchase of 16,635 shares of Common Stock issued
     pursuant to a stock option exchange program in 1995.

                        OPTION GRANTS IN LAST FISCAL YEAR

     The following  table  contains  information  concerning  the grant of stock
options under the Plan to the Named Officers during 1997.


                                       9

<PAGE>

<TABLE>
- ------------------------------------------------------------------------------------------------------------------------------------
<CAPTION>
                                                  Individual Grants
                             --------------------------------------------------------
                              Number of       % of Total                                         Potential Realizable Value at      
                             Securities         Options                                          Assumed Annual Rates of Stock      
                             Underlying       Granted to     Exercise or                      Price Appreciation for Option Term(4) 
                               Options       Employees in    Base Price    Expiration         --------------------------------------
Name                         Granted (#)      Fiscal Year     ($/Share)       Date             0%($)          5%($)           10%($)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                          <C>                <C>          <C>           <C>               <C>        <C>           <C>       
Richard W. Bauer              53,050(1)          10.59%       $12.75        07/30/07          $0           $425,232      $1,077,548
                              70,733(2)          14.11%        12.75        07/30/07           0            566,976       1,436,731
                              53,050(3)          10.59%        12.75        07/30/07           0            425,232       1,077,548

Michael J. Jeffries           26,197(1)           5.23%        12.75        07/30/07           0            209,991         532,123
                              34,931(2)           6.97%        12.75        07/30/07           0            279,988         709,497
                              26,197(3)           5.23%        12.75        07/30/07           0            209,991         532,123

James L. Russell, Ph.D.       13,099(1)           2.61%        12.75        07/30/07           0            104,994         266,058
                              17,464(2)           3.48%        12.75        07/30/07           0            139,992         354,745
                              13,099(3)           2.61%        12.75        07/30/07           0            104,994         266,058

Roger C. Stikeleather         15,064(1)           3.01%        12.75        07/30/07           0            120,745         305,971
                              20,084(2)           4.01%        12.75        07/30/07           0            160,994         407,962
                              15,064(3)           3.01%        12.75        07/30/07           0            120,745         305,971

- ------------------------------------------------------------------------------------------------------------------------------------
All Stockholders(5)               N/A               N/A          N/A           N/A            $0        $148,810,898    $377,090,594

All Optionees(6)             501,125            100.00%       $12.44         Various           0           3,921,571       9,938,030

Optionees Gain as a % of
All Stockholders Gain             N/A               N/A          N/A           N/A           N/A                2.6%            2.6%
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>

(1)  The  options  were  granted  on July 31,  1997 when the price of the Common
     Stock, and therefore the exercise price of the options,  was $12.75.  These
     options  would become  exercisable  on July 30,  1999,  provided the option
     holder was then  employed by the Company or sooner if the closing  price of
     the  Common  Stock  as  quoted  on The  Nasdaq  Stock  Market(SM)  for five
     consecutive  trading days was at least $18. As of December 31, 1997, all of
     these options had vested.

(2)  The  options  were  granted  on July 31,  1997 when the price of the Common
     Stock, and therefore the exercise price of the options,  was $12.75.  These
     options  would become  exercisable  on July 30,  1999,  provided the option
     holder was then  employed by the Company or sooner if the closing  price of
     the  Common  Stock  as  quoted  on The  Nasdaq  Stock  Market(SM)  for five
     consecutive  trading  days was at least $20. As of December 31, 1997 all of
     these options had vested.

(3)  The  options  were  granted  on July 31,  1997 when the price of the Common
     Stock, and therefore the exercise price of the options,  was $12.75.  These
     options  would become  exercisable  on July 30,  1999,  provided the option
     holder was then  employed by the Company or sooner if the closing  price of
     the  Common  Stock  as  quoted  on The  Nasdaq  Stock  Market(SM)  for five
     consecutive  trading  days was at least $22. As of December 31, 1997 all of
     these options had vested.

(4)  The dollar amounts under these columns are the result of calculations at 0%
     and the 5% and 10% rates set by the Securities and Exchange  Commission and
     therefore are not intended to forecast  possible  future  appreciation,  if
     any,  of the  Company's  stock  price.  Any  valuation  model  utilized  to
     calculate future stock  appreciation and valuation requires a prediction of
     the  Company's  stock  price,  and thus,  could  place the  Company  in the
     position  of  predicting  a future  stock  price that would most  likely be
     incorrect.  Therefore,  the  Company did not use an  alternative  valuation
     method, as it is unaware of any method which will determine with reasonable
     accuracy a present value based on future unknown factors.



                                       10

<PAGE>

(5)  The  "Potential  Realizable  Value at Assumed  Annual  Rates of Stock Price
     Appreciation  for Option Term" is the incremental  gain to all stockholders
     as a group which would result from the application of the same  assumptions
     applied  to the  Named  Officers'  options  to all  shares  outstanding  at
     December 31, 1997.

(6)  Information  based on all stock  option  grants made to  employees in 1997.
     Exercise price shown is an average of all grants. Options expire on various
     dates from  January  2007 to October  2007.  All options were granted at an
     exercise  price  equal to the fair  market  value  of the  Common  Stock as
     determined  by  the  last  sale  price  as  reported  on The  Nasdaq  Stock
     Market(SM) on the date of grant.

          AGGREGATED OPTION EXERCISES IN LAST FISCAL YEAR AND FISCAL
                             YEAR-END OPTION VALUES

     The following  table sets forth the  information  with respect to the Named
Officers  concerning the exercise of options during 1997 and unexercised options
held as of December 31, 1997.

<TABLE>
- ------------------------------------------------------------------------------------------------------------------------------------
<CAPTION>
                                                                              Number of Securities           Value of Unexercised
                                                                             Underlying Unexercised          In-the-Money Options
                                                                             Options at Year-End (#)          at Year-End ($)(1)

- ------------------------------------------------------------------------------------------------------------------------------------


                                       Shares Acquired      Value
Name                                   on Exercise (#)  Realized ($)(2)    Exercisable    Unexercisable  Exercisable  Unexercisable

- ------------------------------------------------------------------------------------------------------------------------------------

<S>                                      <C>            <C>                 <C>             <C>          <C>             <C>       
Richard W. Bauer                           17,950         $  467,821         366,799         187,084      $6,756,422      $3,819,807

Michael J. Jeffries                        19,579(3)         397,294         224,510          29,375       4,253,414         637,656

James L. Russell, Ph.D                          0                  0          84,912          48,750       1,475,443       1,003,594

Roger C. Stikeleather                     123,367(4)       2,223,915          53,962          26,000         813,855         566,406
- ------------------------------------------------------------------------------------------------------------------------------------
</TABLE>


- ----------

(1)  The amount  represents  the  difference  between the  exercise  price and a
     market  value of $27.25 as  determined  by the last sale price as quoted on
     The Nasdaq Stock Market(SM) on December 31, 1997.

(2)  Calculated by determining  the difference  between the fair market value of
     the shares of Common Stock underlying the options (based upon the last sale
     price as quoted on The Nasdaq Stock Market(SM)),  and the exercise price of
     the options on the date of exercise.

(3)  Consists of the  following  individual  stock option  exercises:  (i) 5,200
     shares acquired on August 1, 1997,  with a value realized of $39,000;  (ii)
     6,329  shares  acquired  on  November  3, 1997,  with a value  realized  of
     $119,219;  and (iii) 8,050 shares  acquired on December  11,  1997,  with a
     value realized of $239,075.

(4)  Consists of the  following  individual  stock option  exercises:  (i) 1,625
     shares acquired on January 2, 1997,  with a value realized of $2,844;  (ii)
     9,629 shares acquired on February 21, 1997, with a value


                                       11

<PAGE>

     realized of $56,549;  (iii) 7,500 shares  acquired on July 22, 1997, with a
     value  realized of $46,375;  (iv) 28,230 shares  acquired on July 23, 1997,
     with a value realized of $252,262;  (v) 69,633 shares  acquired on December
     3,  1997,  with a value  realized  of  $1,710,762;  and (vi)  6,750  shares
     acquired on December 11, 1997, with a value realized of $155,123.

                        COMPENSATION COMMITTEE INTERLOCKS
                            AND INSIDER PARTICIPATION

     Only Messrs.  Johnston and Fallon and Dr. Sogin served on the  Compensation
Committee  during  the  fiscal  year  ended  December  31,  1997.  None of these
directors  has ever been an employee of the Company or any of its  subsidiaries.
During the fiscal year ended  December  31, 1997,  no  executive  officer of the
Company served on the compensation  committee or board of directors of any other
entity  which had any  executive  officer  who also  served on the  Compensation
Committee or Board of Directors of the Company.

                   REPORT OF THE COMPENSATION COMMITTEE OF THE
                               BOARD OF DIRECTORS

     The  Compensation  Committee  of the Board of Directors  (the  "Committee")
consists entirely of non-employee directors and determines all compensation paid
or awarded to the  Company's  executive  officers.  The  Committee  believes the
Company must retain, adequately compensate and financially motivate talented and
ambitious  managers capable of leading the Company's planned expansion in highly
competitive  fields,  in which many of the  Company's  competitors  have greater
total resources.  The Committee's goal is to use the Company's  resources wisely
by  attracting  and  retaining  the  most  effective  and  efficient  management
organization  the Company can justify.  In determining  the  compensation of the
executive  officers in 1997,  the Committee  utilized the standards set forth in
the Salary  Administration  Program and the Executive Performance Bonus Program,
which  were  adopted  by the  Committee  in  consultation  with  an  independent
management compensation consulting firm and are summarized below.

Overview

     Executive officers'  compensation consists principally of three components:
(i) base salary; (ii) cash bonus; and (iii) stock options.

     The Committee  believes that the best interests of its stockholders will be
served if the executive officers are focused on the long-term  objectives of the
Company,  as well as the current year's goals. The Committee views stock options
as an important long-term incentive vehicle for its executive officers.  Options
provide  executives  with the opportunity to buy and maintain an equity interest
in the Company and to share, along with other stockholders,  in the appreciation
of the value of its Common



                                       12

<PAGE>

Stock which the Committee  believes  would be due largely to the efforts of such
executives.

     All  options  granted  under the Plan are  granted at least at fair  market
value at the time of grant, and therefore any value which ultimately  accrues to
executive  officers is based  entirely on the Company's  stock  performance  and
bears a direct relationship to value realized by the Company's stockholders.  At
the Board's  determination,  options generally vest at the rate of 25% each year
over a four (4) year period  commencing  on the first  anniversary  of the grant
date and are exercisable for a period of ten (10) years from the grant date.

     The 1994 Employee Stock Purchase Plan (the "1994 Stock Purchase  Plan") was
adopted in January 1994 by the Board,  approved by the stockholders in June 1994
and went into effect in August 1994.  The Committee  believes that all employees
of the  Company  and its  subsidiaries  should be provided  the  opportunity  to
acquire or increase their holdings of the Company's  Common Stock.  All eligible
employees,  including  executive  officers,  who  participate  in the 1994 Stock
Purchase Plan have  deductions  made by the Company from their  compensation  to
purchase the Company's  Common Stock  quarterly at a purchase price equal to 85%
of the reported last sale price of the Company's Common Stock on the last day of
each quarter.

     It should  also be noted that:  (i)  exceptions  to the general  principles
stated  herein  are made  when  the  Committee  deems  them  appropriate  to the
stockholders'  interest;  (ii) the Committee  regularly considers other forms of
compensation and modifications of its present policies, and will make changes as
it deems  appropriate;  and (iii)  the  competitive  opportunities  to which the
Company's  executives  are exposed  frequently  come from  private  companies or
divisions of large  companies,  for which published  compensation  data is often
unavailable,  with  the  result  that the  Committee's  information  about  such
opportunities is often anecdotal.

     Certain provisions of the Internal Revenue Code impose conditions to be met
in order for a publicly held corporation to deduct  compensation paid to certain
employees in excess of $1 million per year per employee as compensation  expense
for Federal income tax purposes.  Prior to 1997 individual officer  compensation
levels had not approached  this $1 million  limit.  The increase in the value of
the Company's Common Stock will make it more likely that the total  compensation
of officers may exceed this limit,  since the spread  between the exercise price
of options  and the fair market  value of the Common  Stock on the date of grant
must be included in the  compensation of an employee in determining  whether the
limit is  exceeded.  The  Committee  intends  to  examine  whether  its  various
compensation   plans,   including  the  Plan,   should  be  modified  to  enable
compensation  in excess of such limit to be  deductible  for Federal  income tax
purposes in the future.



                                       13

<PAGE>

Salary and Bonus Programs

     The salaries and bonuses paid to the executive  officers were determined in
accordance with the Company's  Salary  Administration  Program and the Executive
Performance  Bonus  Program  adopted  by  the  Committee.  These  programs  were
developed in consultation with an independent management compensation consulting
firm.

     The range of salary  levels  was  established  based  upon the  competitive
factors in the  marketplace  and the level of the executive  officer's  position
within the Company's  management  structure.  The actual salary paid within such
range is based,  initially,  on qualifications,  and on an ongoing basis, upon a
combination   of   qualifications   and  the  executive   officer's   individual
performance.  Increases in salaries are based upon a performance appraisal which
is conducted  annually by the Committee.  All executive officers are in the same
salary grade,  except for the Chief Executive  Officer who is in a higher salary
grade.  Each salary  grade has a midpoint,  minimum  and maximum  salary  level.
Currently,  the executive  officers are paid salaries  which are in the midpoint
range. Based upon a survey conducted by the independent management  compensation
consultant  retained by the Committee at the time this program was instituted in
1995,  the Committee  believes that the salaries paid to its executive  officers
are  generally  within the  mid-range of salaries  paid to executives in similar
positions at comparable  companies with which the Company competes for executive
talent.

     The primary  objective of the  Executive  Performance  Bonus  Program is to
provide incentives to the executive officers and other key members of management
to achieve  financial  and  business  objectives.  The  Program is  designed  to
emphasize and improve the Company's performance, focus management's attention on
the key priorities and goals of the Company, reward significant contributions to
the Company's  success and attract and retain  results-oriented  executives  and
managers.  Prior to 1997,  the bonus payouts for  executive  officers were based
upon a combination of individual and Company performance. For 1997 and the years
thereafter,  the  Compensation  Committee  has decided to look solely at Company
performance  when  determining  bonus  amounts  for  executive  officers  of the
Company.  Except  for the Chief  Executive  Officer,  in a year of  satisfactory
accomplishment  of Company goals the range of bonuses for executive  officers is
generally 14% to 23% of base salary.  Bonus payouts can exceed these ranges when
the Company  exceeds its profit  before  taxes  ("PBT")  goal,  and  conversely,
significant  under performance of Company goals could result in the reduction or
suspension of bonuses at the executive level.

     Executive  officers  who are  eligible  for a bonus  are also  eligible  to
receive stock options. An annual targeted number of options has been established
by the Committee  based upon the salary grade of each  executive  officer.  This
number is reviewed by the Committee periodically. The number of options actually
granted will



                                       14

<PAGE>

be based  upon the  individual  performance  of the  executive  officer  and the
Committee's  assessment of the executive  officer's ability to contribute to the
enhancement of shareholder  value in the future.  In July 1997 the Board awarded
options  to  certain  officers,  including  all of  the  Named  Officers,  which
contained a provision  providing  for  accelerated  vesting if the Common  Stock
reached  certain  prices.  As set forth in the table entitled  "Option Grants in
Last Fiscal  Year," the price of the Common Stock at the time these options were
granted,  and  therefore the exercise  price of the options,  was $12.75 and the
options  vested in tranches of 30%,  40% and 30% if the Common  Stock  closed at
prices equal to at least $18, $20 and $22,  respectively,  for five  consecutive
trading  days.  The purpose of these options was to provide the officers with an
incentive to continue to take actions designed to increase shareholder value. As
of December 31, 1997, all of these accelerated  vesting  thresholds had been met
and all such options had vested.

Chief Executive Officer's Compensation

     The base salary and bonus of the Chief Executive  Officer are determined by
the Compensation  Committee in accordance with the Salary Administration Program
and Executive  Performance  Bonus Program  discussed  above. The Chief Executive
Officer,  however,  is in his own  salary  grade  and in a year of  satisfactory
accomplishment  of  Company  goals the  range of bonus  for the Chief  Executive
Officer is generally  20% to 33% of base salary.  The bonus payout for the Chief
Executive Officer can exceed these ranges when the Company exceeds its PBT goal,
and conversely,  significant  under performance of Company goals could result in
the  reduction  or  suspension  of bonus for the Chief  Executive  Officer.  The
differences  between the compensation  level of the Chief Executive  Officer and
that of the other  executive  officers are due to the  Compensation  Committee's
acknowledgement  of the importance of the Chief Executive Officer to the success
of the Company's business.

     Effective April 1, 1997 and 1998, Mr. Bauer's base annual salary was set at
$285,000 and $300,000,  respectively.  The Compensation  Committee believes that
Mr. Bauer's  compensation is in line with  compensation  paid to Chief Executive
Officers of comparable companies.

     Mr. Bauer is eligible to receive stock options under the Plan.  The options
granted to Mr.  Bauer will have no value if the  Company's  stock price is below
the relevant exercise prices. The primary purpose of these options is to provide
a strong  incentive  for Mr.  Bauer to  continue  to serve the  stockholders  by
remaining the Chief  Executive  Officer of the Company and to increase the value
of the Company during the remainder of his employment. Mr. Bauer participated in
the July 1997 option grant described in "Salary and Bonus Programs" above.

     The  determination  of Mr.  Bauer's  1997  compensation  and  planned  1998
compensation were based on the Compensation  Committee's favorable assessment of



                                       15

<PAGE>

his ability to build the long-term value of the Company and to manage its future
expansion. This determination was made, in part, by the Compensation Committee's
review of the success of the Company  since Mr.  Bauer has been Chief  Executive
Officer. In addition,  the Compensation  Committee  considered the fact that the
Company exceeded its 1997 PBT goals.


                                                  COMPENSATION COMMITTEE
                                                  Donald D. Johnston, Chairman
                                                  Kenneth P. Fallon, III
                                                  Stephen J. Sogin, Ph.D


Employment Agreements

     On  December  5, 1996,  the  Company  entered  into a  two-year  employment
agreement with Richard W. Bauer, effective as of that date. Under his employment
agreement, Mr. Bauer agreed to serve as President and Chief Executive Officer of
the Company at a minimum  annual  salary of  $265,000,  as adjusted  based on an
annual review by the Board.  Effective  April 1, 1997,  Mr.  Bauer's base annual
salary was increased to $285,000,  and effective April 1, 1998, it was increased
to $300,000.  Pursuant to the employment agreement, Mr. Bauer received an option
to purchase  100,000  shares of the Company's  Common Stock at a price of $10.00
per  share.  The fair  market  value at the time of such  grant was  $6.00.  One
quarter  (1/4) of the option vested on the day before the first  anniversary  of
the effective  date of the  employment  agreement and an additional  one quarter
(1/4)  of the  option  will  vest  on the day  before  each  of the  next  three
anniversaries  of such  effective  date,  provided that Mr. Bauer remains in the
employ of the  Company as of the  relevant  vesting  date.  The  option  will be
exercisable as to each tranche of shares commencing on the relevant vesting date
and ending on the tenth (10th) anniversary of the grant date, and will terminate
as to any vested portion  ninety (90) days after the  termination of Mr. Bauer's
employment  with the Company.  In addition,  under the  agreement,  Mr. Bauer is
entitled  to an  annual  bonus in an amount as  determined  by the  Compensation
Committee.  If  terminated  without  cause,  Mr.  Bauer is  entitled  under  the
agreement to receive a severance  payment  equal to two (2) years'  salary.  Mr.
Bauer's  employment   agreement  also  contains  certain   confidentiality   and
non-competition provisions.

     On January 1, 1998, the Company  entered into an employment  agreement with
Michael  J.  Jeffries  that  has an  initial  term of two  (2)  years  and  will
automatically renew for successive additional two (2) year terms unless at least
three (3) months prior to the end of the initial or any subsequent two-year term
the Company  terminates the agreement by written notice to Mr.  Jeffries.  Under
his  employment  agreement,  Mr.  Jeffries  agreed  to serve as  Executive  Vice
President, Chief Operating Officer and Chief Financial Officer of the Company at
a  minimum  annual  salary of



                                       16

<PAGE>

$198,000,  as adjusted from time to time at the  discretion of the  Compensation
Committee.  Effective April 1, 1998, Mr. Jeffries' base annual salary was set at
$210,000 by the Compensation  Committee.  He is also entitled to an annual bonus
in an amount as determined by the Compensation  Committee. If terminated without
cause,  Mr.  Jeffries is  entitled  under the  agreement  to receive a severance
payment  equal to twelve (12) months'  base salary  payable in twelve (12) equal
monthly installments.  In connection with the employment agreement, Mr. Jeffries
entered into Confidential Information,  Invention and Non-Competition Agreements
with the Company.

     On December 18, 1997, the Company entered into an employment agreement with
James L. Russell,  Ph.D.,  the initial term of which will expire on December 31,
1999, and which will automatically renew for successive  additional two (2) year
terms  unless at least  three  (3)  months  prior to  December  31,  1999 or the
expiration  date of any subsequent two (2) year term the Company  terminates the
agreement by written notice to Dr. Russell. Under his employment agreement,  Dr.
Russell agreed to serve as Executive Vice President and Chief Scientific Officer
of the Company at an annual salary of $178,008,  which will be reviewed annually
and may be  adjusted  from time to time in the  discretion  of the  Compensation
Committee.  Effective April 1, 1998, Dr. Russell's base annual salary was set at
$188,000.  He is also  entitled to an annual bonus in an amount as determined by
the Compensation Committee. If terminated without cause, Dr. Russell is entitled
under the agreement to receive a severance  payment equal to twelve (12) months'
base salary  payable in twelve (12) equal  monthly  installments.  In connection
with  the  employment   agreement,   Dr.  Russell   entered  into   Confidential
Information, Invention and Non-Competition Agreements with the Company.

     On January 1, 1998, the Company  entered into an employment  agreement with
Roger  C.  Stikeleather  that  has an  initial  term of two (2)  years  and will
automatically renew for successive additional two (2) year terms unless at least
three (3) months prior to the end of the initial or any subsequent two-year term
the Company  terminates  the  agreement by written  notice to Mr.  Stikeleather.
Under his employment  agreement,  Mr.  Stikeleather agreed to serve as Executive
Vice  President,  Sales and  Marketing  of the  Company  at a minimum  salary of
$170,040,  as adjusted from time to time in the  discretion of the  Compensation
Committee.  Effective April 1, 1998, Mr.  Stikeleather's  base annual salary was
set at $182,000 by the Compensation  Committee. He is also entitled to an annual
bonus in an amount as determined by the  Compensation  Committee.  If terminated
without  cause,  Mr.  Stikeleather  is entitled under the agreement to receive a
severance  payment  equal to twelve (12) months'  base salary  payable in twelve
(12) equal monthly  installments.  In connection with the employment  agreement,
Mr.   Stikeleather   entered  into  Confidential   Information,   Invention  and
Non-Competition Agreements with the Company.



                                       17

<PAGE>

Change In Control Agreements

     In September  1997, the Company  entered into change in control  agreements
with  certain  officers of the Company  including  Richard W. Bauer,  Michael J.
Jeffries,  James L. Russell and Roger C. Stikeleather to assure that the Company
will  have  their  continued   dedication  as  executives   notwithstanding  the
possibility,  threat or occurrence of a change in control of the Company.  Under
the change in control agreements, a change in control is defined as (i) a change
in the Board of  Directors  of the Company  such that a majority of the Board is
made up of  persons  who were  neither  nominated  nor  appointed  by  incumbent
Directors,  (ii) the  acquisition by any person of a majority of the outstanding
voting securities of the Company,  except if such acquisition is effected by the
Company  itself,  by an employee  benefit  plan of the Company or pursuant to an
offering  by  the  Company  of  its  voting   securities,   (iii)  a  merger  or
consolidation  of the Company with another company such that neither the Company
nor any of its  subsidiaries  will be the  surviving  entity,  (iv) a merger  or
consolidation  of  the  Company  following  which  the  Company  or  a  previous
subsidiary  of the Company  will be the  surviving  entity and a majority of the
voting  securities  of the Company will be owned by a person or persons who were
not beneficial  owners of a majority of the Company's voting securities prior to
such merger or consolidation,  (v) a liquidation of the Company,  or (vi) a sale
or disposition by the Company of at least 80% of its assets.

     Under the agreements,  for one (1) year after the occurrence of a change in
control, each executive will remain in the Company's employ in the same position
he held  before the change in control  and will be entitled to a base salary and
benefits no less favorable  than those in effect for such executive  immediately
preceding  the change in control.  In  addition,  upon a change in control,  all
unvested stock options held by each executive,  will vest and become exercisable
immediately,  notwithstanding  anything to the contrary  contained in the option
certificates  or any plan  covering  such options.  If,  however,  the change in
control arises from a merger or  consolidation  in which neither the Company nor
any of its  subsidiaries is the surviving  entity or from the liquidation of the
Company,  each  executive  will  instead be given a  reasonable  opportunity  to
exercise such options prior to the change in control and any such options not so
exercised will terminate on the effective date of the change in control.

     Upon a change in control,  each  executive  is  entitled  to an  additional
payment equal to a given number (see table below),  multiplied by (i) the amount
by which the payment per share received or to be received by the shareholders of
the Company in connection  with such change in control  event exceeds  $12.75 or
(ii) if there is no such  payment,  the amount by which the  average of the last
reported sale price of the Company's  Common Stock for the five (5) trading days
immediately preceding such change in control exceeds $12.75:



                                       18

<PAGE>

             Mr. Bauer......................................  228,167
             Mr. Jeffries...................................  112,675
             Mr. Russell....................................   56,338
             Mr. Stikeleather...............................   64,788

     The  agreements  also  provide  that if,  after a  change  in  control,  an
executive's  employment is  terminated  for any reason,  the  executive  will be
entitled to receive all then accrued pay, benefits,  executive  compensation and
fringe  benefits,  including pro rata bonus and incentive plan earnings  through
the date of his  termination  plus the amount of any  compensation he previously
deferred,  in each case, to the extent theretofore  unpaid. In addition,  unless
the executive's  employment was terminated by the executive  without good reason
(as  defined  below) on or prior to the 180th  day after the  change in  control
event or by the Company for just cause (as defined in the agreement) on or prior
to the 180th day after the change in control  event,  the executive will receive
(i) a payment  equal to three (3) times his average  annual gross income for the
five taxable years prior to the change in control event, plus interest, and (ii)
at the Company's expense,  medical, health and disability benefits comparable to
those he received prior to the change in control for a period of three (3) years
following his termination.  Furthermore,  unless the executive's  employment was
terminated by the executive  without good reason prior to the first  anniversary
of the change in control event or was  terminated by the Company for just cause,
the  executive  will also be entitled  to (i) the balance of all pay,  benefits,
compensation and fringe benefits including (but not limited to) pro rata salary,
bonus and incentive plan earnings  payable through the first  anniversary of the
change in control event, and (ii) an office and reasonable secretarial and other
services from the Company for one year from the date of his termination.

     For purposes of the change in control agreements, good reason includes, (A)
the assignment to the executive of duties which are not  substantially  of equal
status,  dignity and character as the duties performed  immediately prior to the
change in control,  (B) the failure of the Company to provide full  compensation
as  contemplated by the change in control  agreement,  (C) the relocation of the
executive's  office to a location  more than  fifteen  miles  from the  location
required  immediately  prior to the change in control,  or his being required to
travel to a much greater extent than required immediately prior to the change in
control in order to perform duties of  substantially  equal status,  dignity and
character to those performed prior to the change in control,  (D) the failure of
a successor  corporation to expressly  assume and agree to perform the Company's
obligations under the change in control  agreement,  provided such successor has
received at least twenty (20) days prior written notice of such obligations, and
(E) the  voluntary  termination  by the executive for any reason after the 180th
day  following  the change in control.  Except with  respect to section (E), the
determination that good reason exists requires that the employee



                                       19
<PAGE>

make such determination in good faith, notify the Company of his or her position
in writing and provide twenty (20) days for the Company to cure.

     Each of these  agreements  has an initial  term of three (3) years and will
automatically  renew on each  successive  annual  anniversary  for an additional
three (3) years,  unless the Company gives the executive officer sixty (60) days
notice  prior to the  anniversary  date  that it does  not  plan to  renew  such
contract.

                      STOCKHOLDER RETURN PERFORMANCE GRAPH

     The graph below summarizes the total cumulative  return  experienced by the
Company's  stockholders  during the  five-year  period ended  December 31, 1997,
compared to the Nasdaq  Stock Market  Index and the Dow Jones  Medical  Supplies
Index. The changes for the periods shown in the graph and table are based on the
assumption  that $100.00 had been invested in Osteotech,  Inc. stock and in each
index below on January 1, 1993 and that all dividends were reinvested.

[PERFORMANCE GRAPH TO COME]

<TABLE>
<CAPTION>
- ------------------------------------------------------------------------------------------------------------------

                                Jan. 1                                         December 31,
- ------------------------------------------------------------------------------------------------------------------
                                1993                1993           1994            1995        1996         1997
                                ----                ----           ----            ----        ----         ----

<S>                            <C>                 <C>            <C>             <C>         <C>          <C>    
Osteotech, Inc.                $100.00             $ 69.64        $ 62.50         $100.00     $100.00      $389.29

Nasdaq Stock Market(SM)        $100.00              115.76         112.28          157.69      193.09       236.22

Dow Jones Medical Supplies     $100.00               93.46         114.38          155.69      187.82       222.67
- ------------------------------------------------------------------------------------------------------------------
</TABLE>

                    SECURITY OWNERSHIP OF CERTAIN BENEFICIAL
                              OWNERS AND MANAGEMENT

     The following table sets forth certain  information as of February 28, 1998
concerning  stock  ownership  of  all  persons  known  by  the  Company  to  own
beneficially 5% or more of the outstanding shares of the Company's Common Stock,
each director of the Company, each executive officer of the Company named in the
Summary  Compensation  Table and all  executive  officers  and  directors of the
Company as a group:



                                       20

<PAGE>

<TABLE>
<CAPTION>
     Name and Address                                                                        Amount and            Percent
       of Beneficial                                                                           Nature                of
         Owner or                                                                           of Beneficial           Stock
   Identity of Group (1)                                                                      Ownership          Outstanding(2)
- ------------------------------------------------------------------------------------------------------------------------------
<S>                                                                                         <C>                     <C> 
George D. Bjurman & Associates,
 George Andrew Bjurman and
 Owen Thomas Barry III...............................................................         765,145(3)              8.6%
 10100 Santa Monica Blvd, Ste 1200
 Los Angeles, CA 90067

Essex Investment Management Company..................................................         516,050(3)              5.8%
 125 High Street
 Boston, MA 02110

Jan Philipp F. Reemtsma..............................................................         452,610(4)              5.1%
  c/o Rho Management Company, Inc.
  641 Lexington Avenue, 18th Floor
  New York, NY 10022

Richard W. Bauer.....................................................................         385,897(5)              4.2%

Michael J. Jeffries..................................................................         253,829(6)              2.8%

James L. Russell, Ph.D...............................................................          84,912(7)              1.0%

Roger C. Stikeleather................................................................          58,962(8)                *

Donald D. Johnston...................................................................         354,500(9)              3.9%

Kenneth P. Fallon, III...............................................................           7,500(10)               *

John Phillip Kostuik, M.D., FRCS(C)..................................................               0                   *

Stephen J. Sogin, Ph.D...............................................................             248                   *

All executive officers and directors as a group (8 persons) .........................       1,145,848(11)            11.8%
</TABLE>
- ----------

*    Less than one percent

(1)  Unless otherwise  indicated below, the persons in the above table have sole
     voting and investment power with respect to all shares  beneficially  owned
     by them.

(2)  The percentage of stock  outstanding for each  stockholder is calculated by
     dividing (i) the number of shares  deemed to be  beneficially  held by such
     stockholder  as of  February  28, 1998 by (ii) the sum of (A) the number of
     shares of Common  Stock  outstanding  as of February  28, 1998 plus (B) the
     number of shares issuable upon exercise of options or warrants held by such
     stockholder  which were  exercisable  as of February 28, 1998 or which will
     become exercisable within 60 days after February 28, 1998.

(3)  This  information  was taken  from the  Company's  review of its  record of
     stockholders and warrantholders as of February 28, 1998.



                                       21

<PAGE>

(4)  This information was obtained from a Schedule 13G filed with the Securities
     and Exchange Commission on February 13, 1995.

(5)  Includes 372,466 shares underlying options which are currently  exercisable
     or which will become exercisable within 60 days of February 28, 1998.

(6)  Includes 209,510 shares underlying options which are currently  exercisable
     or which will become exercisable within 60 days of February 28, 1998.

(7)  Includes 84,912 shares underlying  options which are currently  exercisable
     or which will become exercisable within 60 days of February 28, 1998.

(8)  Includes 58,962 shares underlying  options which are currently  exercisable
     or which will become exercisable within 60 days of February 28, 1998.

(9)  Includes 130,000 shares underlying options which are currently  exercisable
     or which will become  exercisable  within 60 days of February  28, 1998 and
     includes 10,000 shares of Common Stock beneficially owned by Mr. Johnston's
     wife of which he disclaims beneficial ownership.

(10) Includes 7,500 shares underlying options which are currently exercisable or
     which will become exercisable within 60 days of February 28, 1998.

(11) Includes options and warrants to purchase an aggregate of 863,350 shares of
     Common  Stock  which  are  currently   exercisable  or  which  will  become
     exercisable within 60 days of February 28, 1998.

                 CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     The Company has made three loans to Michael J.  Jeffries to fund  exercises
of stock options and the payment of taxes  incurred by Mr.  Jeffries as a result
of such exercises.  The first loan of $103,646 was made on June 17, 1996,  bears
interest at the rate of 6.7% per annum and is due on June 16,  2001.  The second
loan of $41,332  was made on August 1, 1997,  bears  interest at a rate of 6.12%
per annum and is due on July 31,  2002.  The third loan of  $45,863  was made on
November  3,  1997,  bears  interest  at a rate of 5.9% per  annum and is due on
November 2, 2002.  The loans  require  payments  of interest  only on a calendar
quarter basis with  principal  due at their  respective  maturity  dates and are
secured  by the stock  certificates  issued as a result of the  exercise  of the
options for which the respective loans were made. The Board approved these loans
in order to enable Mr.  Jeffries to exercise  his options and to  encourage  Mr.
Jeffries to hold the shares  received upon such  exercises,  rather than to sell
such shares in order to fund the exercise price and pay related taxes.

     On June 5, 1997, Dr. Stephen J. Sogin received an option to purchase 20,000
shares at an exercise  price of $9.50 for  consulting  services  rendered to the
Company.



                                       22

<PAGE>

           PROPOSALS NO. 2 AND NO. 3 - RATIFICATION OF THE AMENDMENTS
                         TO THE 1991 STOCK OPTION PLAN.

     The  Company's   Board  has   unanimously   approved  and  recommended  for
stockholder approval amendments to the Plan.

     The proposed amendments would modify the Plan to (i) increase the number of
Common  Shares  reserved  for  issuance  under  the Plan by  818,624  shares  to
2,813,765 shares and (ii) reflect changes made to Rule 16b-3  promulgated  under
Section 16(b) of the Securities Exchange Act of 1934, as amended.

     The Board believes that the Plan is in the best interest of the Company and
is important to  attracting,  motivating and retaining  qualified  Employees (as
defined in the Plan),  officers,  directors  and  consultants  essential  to the
success of the Company.  The Company is proposing the  amendments to the Plan to
conform to the current  provisions  of Rule 16b-3 and to increase  the number of
shares reserved for issuance under the Plan.

Summary of Current Plan

     In 1991, the Board adopted and the stockholders  ratified the Plan covering
813,765 shares of the Company's  Common Stock pursuant to which  Incentive Stock
Options (as defined in the Plan) are granted to Employees (sometimes referred to
as  "optionees")  and  Non-statutory  Stock  Options are  granted to  Employees,
officers,  directors or consultants of the Company (also,  sometimes referred to
as "optionees").  Under the Plan, Employees include any individual (including an
officer or a director)  who is an employee of the Company  within the meaning of
Section  3401  of the  Internal  Revenue  Code  of  1986,  as  amended,  and the
regulations thereunder.  The Plan was amended by vote of the stockholders at the
Annual  Meetings  on June 24,  1993 to  increase  the number of shares of Common
Stock reserved for options under the Plan by 450,000 shares to 1,263,765  shares
and on June 23, 1994 to increase the number of shares reserved for options under
the Plan by 550,000 shares to 1,813,765 shares.  The Plan was further amended by
approval of the Board of  Directors  on July 31, 1997 to increase  the number of
shares  reserved  for options  under the Plan by  1,000,000  shares to 2,813,765
shares,  with the understanding that, in accordance with the rules of The Nasdaq
Stock  Market(SM),  818,624  shares of the  1,000,000  share  increase  would be
subject to  approval by the  requisite  vote of the  stockholders  at the Annual
Meeting to which this Proxy Statement pertains.

     Pursuant to the Plan, any Employee may be granted  Incentive  Stock Options
and any  Employee  or  officer,  director  or  consultant  of the Company may be
granted  Non-statutory  Stock  Options  if, in each  instance,  the Board or the
Board's Compensation  Committee determines that such person performs services of
special importance to the management, operation and development of the Company's
business. Each option granted under the Plan has an exercise price determined by
the



                                       23

<PAGE>

Board  or the  Board's  Compensation  Committee  that  is (i) in the  case of an
Incentive  Stock  Option  granted  to an  Employee  who  is  not  a Ten  Percent
Shareholder (as defined in the Plan), not less than the fair market value of the
Common Shares to which such option relates on the date of the grant, (ii) in the
case of an Incentive  Stock  Option  granted to an Employee who is a Ten Percent
Shareholder, not less than 110% of the fair market value of the Common Shares to
which such option relates on the date of the grant,  and (iii) in all cases, not
less  than the par value of the  Common  Shares to which  such  option  relates.
Incentive Stock Options  granted  pursuant to the Plan are not exercisable for a
period of one (1) year following the date of grant,  and  thereafter,  Incentive
Stock Options and, in all cases, Non-statutory Stock Options may be exercised as
determined by the Board or the Compensation  Committee.  In all cases,  however,
Incentive   Stock  Options   granted  to  Employees  who  are  not  Ten  Percent
Shareholders  and those  granted to Employees  who are Ten Percent  Shareholders
expire ten (10) years and five (5) years,  respectively,  from the date they are
granted.  Each option granted under the Plan is  nontransferable,  other than by
will or by the laws of descent and  distribution.  The Plan also  provides  that
Incentive and  Non-statutory  Stock Options granted to optionees who cease to be
employed by the Company for any reason remain  exercisable  for three (3) months
(twelve (12) months if the termination  was due to the death,  disability or, in
the case of a Non-statutory Stock Option, retirement of the optionee) after such
termination  of employment  or any other time period  determined by the Board or
the  Board's   Compensation   Committee.   However,  the  right  to  exercise  a
Non-statutory  Stock Option  terminates  immediately  upon the termination of an
optionee's employment for cause.

     Unless  otherwise  permitted  by  the  Board  or the  Board's  Compensation
Committee,  to exercise an option under the Plan, the optionee must give written
notice to the Company specifying the number of Common Shares to be purchased and
accompanied by payment in cash or by certified  check of the full exercise price
for each Common Share to be acquired.

     The Plan  provides that if the Company is the  surviving  corporation  in a
merger or consolidation,  each outstanding option shall pertain and apply to the
securities  to which a holder  of the  number of Common  Shares  subject  to the
option would have been  entitled in such merger or  consolidation.  In the event
that the Company is not the surviving corporation in any merger or consolidation
or the Company dissolves or liquidates, each outstanding option shall terminate,
unless  the  agreement  of  merger or  consolidation  shall  otherwise  provide.
However,  optionees  who have held their  options for at least one (1) year from
the date of grant  shall  have the  right  immediately  prior to such  merger or
consolidation  or  dissolution or liquidation to exercise their options in whole
or in part, regardless of whether such options are otherwise exercisable at that
time.

     During the fiscal  year ended  December  31,  1997,  the only  non-employee
director  who  received  a grant of  options  under the Plan was Dr.  Stephen J.
Sogin. There were



                                       24

<PAGE>

grants of options  pursuant  to the Plan to  employees  as a group to acquire an
aggregate of 481,125  shares of Common Stock,  at exercise  prices  ranging from
$7.625 to $19.50 per share,  during the fiscal year ended  December 31, 1997. As
of December 31, 1997,  there were an  aggregate  of 195 options  outstanding  to
acquire 1,445,325 shares.  For information  regarding grants of options received
by executive officers, see "Option Grants in Last Fiscal Year."

Proposed Amendments to Plan

     Proposal  No. 2 would  increase  the number of Common  Shares  reserved for
issuance under the Plan by 818,624 shares to 2,813,765 shares.

     In addition,  the Plan currently  contains  certain  provisions  which were
designed to comply with the  requirements  of Rule 16b-3 as  previously  enacted
("Old Rule 16b-3").  The amendments  provided for in Proposal No. 3 are designed
to reflect the current  provisions of Rule 16b-3 adopted by the  Securities  and
Exchange Commission in May 1996 ("Current Rule 16b-3"), as follows:

     First, the concept of a "disinterested  person" will be eliminated from the
Plan. The Plan currently  provides that the options may not be granted under the
Plan unless each member of the Board or the Compensation  Committee of the Board
(which may  administer  the Plan) is a  "disinterested  person," as such term is
defined in Old Rule 16b-3. The Plan as amended would provide that the Plan is to
be administered by either the Board or the  Compensation  Committee and that the
Compensation  Committee  must  consist  solely  of  two  or  more  "non-employee
directors," as such term is defined in Current Rule 16b-3.

     Second,  the  description  of the  circumstances  under  which  stockholder
approval is required before an amendment to the Plan may take place will change.
The Plan  currently  provides  that no amendment may be made to the Plan without
stockholder  approval  where such  amendment  would (i)  increase  the number of
shares  subject  to the  Plan;  (ii)  alter  the class of  persons  eligible  to
participate  in the Plan; or (iii)  materially  increase the benefits  under the
Plan.  These provisions were consistent with the requirements of Old Rule 16b-3.
The Plan as amended  would  provide  that the Plan could be amended by the Board
without  stockholder  approval  unless  stockholder  approval  was  required  by
applicable  law or the  rules of  Nasdaq  or any  stock  exchange  on which  the
Company's shares are then traded.

     If the  foregoing  proposed  amendments  to the  Plan are  approved  by the
stockholders at the Annual Meeting, they shall take effect as of the date of the
Annual Meeting.



                                       25

<PAGE>

     This  description of the proposed  amendments to the Plan is a summary only
and is qualified  in its entirety by reference to the text of the amended  Plan,
which the Company will make available to any shareholder upon request.

Federal Income Tax Consequences

     The  Incentive  Stock  Options  granted under the Plan qualify as incentive
stock options, within the meaning of Section 422 of the Internal Revenue Code of
1986, as amended (the "Code"),  while the  Non-statutory  Stock Options  granted
under the Plan are nonqualified  options. The following general summary is based
upon the  Code and does not  include  a  discussion  of any  state or local  tax
consequences.

Incentive Stock Options

     Under  Section  422 of the  Code,  no  taxable  income is  realized  by the
optionee upon the grant or exercise of an incentive stock option,  provided that
the optionee is continuously employed by the Company during the period beginning
on the date of grant and ending on the date three (3) months  before the date of
exercise  (or,  in the  case of  disability,  one (1)  year  before  the date of
exercise).  However,  the  exercise of an  incentive  stock option may result in
alternative minimum tax liability for the optionee.  If no disposition of shares
issued to an optionee  pursuant to the exercise of an incentive  stock option is
made by the  optionee  within two (2) years from the date of grant or within one
(1) year after the  transfer of such shares to the  optionee,  then upon sale of
such shares,  any amount  realized in excess of the exercise price will be taxed
to the  optionee  as  long-term  capital  gain  and any loss  sustained  will be
long-term  capital  loss,  and no  deduction  will be allowed to the Company for
federal  income tax  purposes.  The grant of an  incentive  stock option and the
optionee's  exercise  of the  incentive  stock  option will result in no federal
income tax consequences to the Company.

     If the shares of Common  Stock  acquired  upon the exercise of an incentive
stock  option  are  disposed  of prior to the  expiration  of the  two-year  and
one-year  holding  periods  described  above  (a  "disqualifying  disposition"),
generally the optionee will realize  ordinary  income in the year of disposition
in an amount equal to the excess (if any) of the fair market value of the shares
at exercise (or, if less,  the amount  realized on an  arms-length  sale of such
shares) over the  exercise  price  thereof,  and the Company will be entitled to
deduct such amount.  Any further gain  realized  will be taxed as  short-term or
long-term capital gain and will not result in any deduction by the Company.



                                       26

<PAGE>

Nonqualified Stock Options

     An optionee will not generally  recognize any taxable income upon the grant
of a nonqualified option because, under current Treasury regulations pursuant to
Section  83 of the Code,  the fair  market  value of an option at the time it is
granted is ordinarily  not  considered to be "readily  ascertainable."  However,
upon exercise of a  nonqualified  option,  an optionee must  recognize  ordinary
income in an amount  equal to the excess of the fair market  value of the Common
Stock at the time of  exercise  over the  exercise  price.  Upon the  subsequent
disposition  of the Common  Stock,  the optionee  will realize a capital gain or
loss,  depending on whether the selling  price  exceeds the fair market value of
the Common Stock on the date of exercise.  The optionee's  holding period in the
Common  Stock,  for  capital  gains and losses  purposes,  begins on the date of
exercise.

     An  optionee's  tax  basis  in  the  shares   received  on  exercise  of  a
nonqualified  option  will be equal to the amount of  consideration  paid by the
optionee on exercise,  plus the amount of ordinary income recognized as a result
of the receipt of such shares.  The Company will be entitled to a deduction  for
federal  income  tax  purposes  at the same  time and in the same  amount as the
optionee   recognizes  taxable  income,   provided  the  Company  satisfies  any
applicable withholding tax obligation with respect to such income.

Closing Price of Common Stock

     The last reported  sales price of a share of the Company's  Common Stock on
April 24, 1998 on The Nasdaq Stock Market(SM) was $22.625.

     The Board of  Directors  recommends a vote FOR the  amendments  to the 1991
Stock Option Plan as proposed. (Proposals No. 2 and No. 3 on the Proxy).

                    PROPOSAL NO. 4 - RATIFICATION OF AUDITORS

     The Audit  Committee  of the Board of Directors  approved the  retention of
Coopers & Lybrand  L.L.P.  as the  Company's  independent  auditors for the year
ending December 31, 1998. They have served as the Company's independent auditors
since 1987.  Representatives  of Coopers & Lybrand  L.L.P.  will be available to
answer questions and make statements at the Annual Meeting.

     The  Board  of  Directors   recommends  a  vote  FOR  ratification  of  the
appointment of Coopers & Lybrand L.L.P.  as the Company's  independent  auditors
for the year ending December 31, 1998 (Proposal No. 4 on the Proxy).



                                       27

<PAGE>

     If  the   appointment  is  not  ratified,   management  will  select  other
independent  auditors.  If the appointment is ratified,  management reserves the
right to appoint other independent auditors.

                          ANNUAL REPORT TO STOCKHOLDERS

     The Company's  1997 Annual Report to  Stockholders  accompanies  this Proxy
Statement.

                             STOCKHOLDERS' PROPOSALS

     In the  event  that a  stockholder  desires  to  have a  proposal  formally
considered at the 1999 Annual  Stockholders'  Meeting, and included in the Proxy
Statement  for that  meeting,  the  proposal  must be received in writing by the
Company's Secretary on or before January 1, 1999.

                                     GENERAL

     The  expenses  of  preparing  and  mailing  this  Proxy  Statement  and the
accompanying form of proxy and the cost of solicitation of proxies will be borne
by the Company. In addition to the use of mailings,  proxies may be solicited by
personal  interview,  telephone and  telegraph,  and by directors,  officers and
regular employees of the Company,  without special  compensation  therefor.  The
Company  expects  to  reimburse  banks,  brokers  and  other  persons  for their
reasonable  out-of-pocket  expenses in handling  proxy  materials for beneficial
owners of the Company's Common Stock.

     Unless  contrary  instructions  are  indicated on the proxy,  all shares of
Common Stock represented by valid proxies received pursuant to this solicitation
(and  not  revoked  before  they  are  voted)  will  be  voted  FOR  all  of the
aforementioned proposals.

     Any proxy given pursuant to this  solicitation may be revoked by the person
giving it at any time before it is voted.  Proxies may be revoked by filing with
the  Secretary of the Company  prior to the date of the Annual  Meeting  written
notice of revocation  bearing a later date than the proxy, by duly executing and
delivering  to the  Secretary  of the  Company  prior to the date of the  Annual
Meeting a  subsequent  proxy  relating to the same shares of Common  Stock or by
attending  the Annual  Meeting  and voting in person.  Attendance  at the Annual
Meeting will not in and of itself  constitute  revocation  of a proxy unless the
stockholder  votes his shares of Common  Stock in person at the Annual  Meeting.
Any notice  revoking a proxy  should be sent to the  Secretary  of the  Company,
Michael J. Jeffries, Osteotech, Inc., 51 James Way, Eatontown, New Jersey 07724,
in a manner designed to ensure that it is received by the Secretary prior to the
date of the Annual Meeting.



                                       28

<PAGE>

                                  OTHER MATTERS

     The Board of Directors  knows of no other matters to be brought  before the
Annual Meeting.  If matters other than the foregoing  should arise at the Annual
Meeting,  it is intended that the shares represented by proxies will be voted in
accordance with the judgment of the persons named in the proxy.

     Please  complete,  sign and date the enclosed proxy,  which is revocable as
described herein, and mail it promptly in the enclosed postage-paid envelope.

                                            By Order of the Board of Directors,




                                            MICHAEL J. JEFFRIES
                                            Secretary


Dated: May 4, 1998



<PAGE>


                                 OSTEOTECH, INC.
                                      PROXY
                                  COMMON STOCK

                          ANNUAL MEETING: JUNE 4, 1998
           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS


     Richard  W.  Bauer and  Michael J.  Jeffries,  and each of them,  to act as
proxies with full power of substitution  in each of them, are hereby  authorized
to represent and to vote, as designated  below and on the reverse side, upon the
following  proposals and in the  discretion of the proxies on such other matters
as may properly  come before the Annual  Meeting of  Stockholders  of Osteotech,
Inc.  to be held at the  Sheraton  Eatontown  Hotel  and  Conference  Center,  6
Industrial Way East,  Eatontown,  New Jersey 07724 on Thursday,  June 4, 1998 at
9:00 A.M. or any adjournment(s),  postponement(s) or other delay(s) thereof (the
"Annual  Meeting"),  all shares of common stock of Osteotech,  Inc. to which the
undersigned is entitled to vote at the Annual Meeting.  The following  proposals
are more fully described in the Notice of Annual Meeting and Proxy Statement for
the Annual Meeting (receipt of which is hereby acknowledged).

     UNLESS OTHERWISE DIRECTED, THIS PROXY WILL BE VOTED "FOR" PROPOSALS 1, 2, 3
AND 4 AND WILL BE VOTED IN THE  DISCRETION  OF THE PROXIES ON SUCH OTHER MATTERS
AS MAY  PROPERLY  COME  BEFORE  THE  ANNUAL  MEETING.  THE  BOARD  OF  DIRECTORS
RECOMMENDS THAT STOCKHOLDERS VOTE "FOR" PROPOSALS 1, 2, 3 AND 4.

(Continued and to be dated and signed on the reverse side.)

                                                    OSTEOTECH, INC.
                                                    51 JAMES WAY
                                                    EATONTOWN, NJ  07724




<PAGE>


<TABLE>
<S>                 <C>                    <C>    <C>                          <C>     <C>               <C>
1. To elect (6)     FOR all nominees       X      WITHHOLD AUTHORITY           X       EXCEPTIONS        X
   directors.       listed below                  for all nominees
                                                  listed below
</TABLE>

     Nominees: Donald D. Johnston, Richard W. Bauer, Michael J. Jeffries,
Kenneth P. Fallon, III, Stephen J. Sogin, Ph.D and John Phillip Kostuik, M.D.,
FRCS(C). (INSTRUCTIONS: TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL
NOMINEE, MARK THE "EXCEPTIONS" BOX AND WRITE THAT NOMINEE'S NAME IN THE SPACE
PROVIDED BELOW.)

Exceptions: ____________________________________________________________________


2.   To approve an amendment to the Company's 1991 Stock Option Plan, as amended
     (the "Plan") to increase the number of shares of Common Stock  reserved for
     issuance under the Plan by 818,624 shares to 2,813,765 shares.

      FOR     X              AGAINST     X          ABSTAIN     X


3.   To approve an amendment to the Plan to conform the Plan to the current
     provisions of Rule 16b-3 under the Securities Exchange Act of 1934.

      FOR     X              AGAINST     X          ABSTAIN     X


4.   To ratify the selection of Coopers & Lybrand L.L.P. as the Company's
     independent auditors for the fiscal year ending December 31, 1998.

      FOR     X              AGAINST     X          ABSTAIN     X


5.   To transact such other business as may properly come before the Annual
     Meeting.


                                  PLEASE CHECK THIS BOX IF YOU EXPECT TO ATTEND
                                  THE ANNUAL MEETING IN PERSON.          X      

                                  (Please sign exactly as name appears to the
                                  left, date and return. If shares are held by
                                  joint tenants, both should sign. When signing
                                  as an attorney, executor, administrator,
                                  trustee or guardian, please give full title as
                                  such. If a corporation, please sign in full
                                  corporate name by president or other
                                  authorized officer. If a partnership, please
                                  sign in partnership name by authorized
                                  person.)

                                  Please Date: _________________________________

                                  Sign Here: ___________________________________


                                  ______________________________________________
                                            Signature (if held jointly)


                                  ______________________________________________
                                  Capacity (Title or Authority, i.e., President,
                                  Partner, Executor, Trustee)

                                  Votes must be indicated
                                  in Black or Blue ink.                     X


PLEASE SIGN AND DATE AND RETURN YOUR PROXY TODAY.





                             PROPOSED AMENDMENTS TO
                             1991 STOCK OPTION PLAN

                                 OSTEOTECH, INC.
                     1991 STOCK OPTION PLAN, AS AMENDED/(1)


     1.   Purpose. The purpose of the 1991 Stock  Option  Plan,  as amended,  of
Osteotech,  Inc. is to provide  incentive to employees  of the  Corporation,  as
defined below, including officers, directors, and consultants, to encourage such
individuals   proprietary  interest  in  the  Corporation,   to  encourage  such
individuals  to remain in the employ of the  Corporation,  and to attract to the
Corporation individuals of experience and ability.

     2.   Definitions.

          a.   "Board" shall mean the Board of Directors of the Company.

          b.   "Code" shall mean the Internal Revenue Code of 1986, as amended.

          c.   "Committee"  shall  mean  the  Compensation  Committee,  which is
               appointed by the Board, and which shall be composed solely of two
               or more Non-Employee Directors.

          d.   "Common  Stock" shall mean the $.01 par value Common Stock of the
               Company.

          e.   "Company" shall mean Osteotech, Inc., a Delaware corporation.

          f.   "Corporation"  shall mean and  include the Company and any parent
               or subsidiary corporation thereof,  within the meaning of Section
               424 of the Code.

          g.   "Disability"  shall  mean the  condition  of an  Employee  who is
               unable to engage in any substantial gainful activity by reason of

- ----------
(1) The  Osteotech,  Inc. 1991 Stock Option Plan (the "1991 Plan"),  as amended,
was  amended by the Board on October  22,  1992 and on January  28,  1993.  Such
amendments were approved by the Stockholders on June 24, 1993. The 1991 Plan was
further  amended by the Board on October 28, 1993 and February  13,  1994.  Such
amendments were approved by the Stockholders on June 23, 1994. The 1991 Plan was
further  amended  by the  Board  on July 31,  1997  and  March  26,  1998.  Such
amendments were approved by the Stockholders on [June 4, 1998].


                                      E-1
<PAGE>


               any medically  determinable  physical or mental  impairment which
               can be  expected to result in death or which has lasted or can be
               expected to last for a continuous  period of not less than twelve
               (12)  months,  all within the meaning of Section  22(e)(3) of the
               Code.

          h.   "Employee"  shall mean any individual  (including an officer or a
               director)  who is an  employee  of the  Corporation  (within  the
               meaning  of  Section  3401  of  the  Code  and  the   regulations
               thereunder).

          i.   "Exercise  Price" shall mean the price per Share of Common Stock,
               determined by the Board or  Committee,  at which an Option may be
               exercised.

          j.   "Fair Market  Value" of a Share of Common Stock as of a specified
               date shall  mean the  closing  price of a Share on the  principal
               securities  exchange  on which such  Shares are traded on the day
               immediately  preceding  the date as of which Fair Market Value is
               being  determined,  or on the next  preceding  date on which such
               Shares are traded if no Shares  were  traded on such  immediately
               preceding  day,  or if the Shares are not traded on a  securities
               exchange,  Fair Market Value shall be deemed to be the average of
               the  high  bid  and  low  asked  Prices  of  the  Shares  in  the
               over-the-counter market on the day immediately preceding the date
               as of which Fair Market Value is being  determined or on the next
               preceding  date on which such high bid and low asked  prices were
               recorded.  If the Shares are not  publicly  traded,  Fair  Market
               Value shall be determined  by the Board or Committee.  In no case
               shall Fair Market  Value be less than the par value of a Share of
               a  Common  Stock,  and in no event  shall  Fair  Market  Value be
               determined  with regard to restrictions  other than  restrictions
               which, by their terms, will never lapse.

          k.   "Incentive  Stock Option" shall mean an Option  described in Code
               Section 422(b).

          l.   "Non-Employee  Director" shall have the meaning  ascribed in Rule
               16b-3 promulgated  under the Securities  Exchange Act of 1934, as
               amended.

          m.   "Non-statutory Stock Option" shall mean an Option which is not an
               Incentive Stock Option.


                                      E-2
<PAGE>


          n.   "Option" shall mean a stock option granted pursuant to the Plan.

          o.   "Optionee"  shall  mean a  person  to whom  an  Option  has  been
               granted.

          p.   "Plan" shall mean this  Osteotech,  Inc., 1991 Stock Option Plan,
               as amended.

          q.   "Purchase  Price" shall mean the Exercise  Price times the number
               of whole Shares with respect to which an Option is exercised.

          r.   "Share" shall mean one share of Common Stock.

          s.   "Ten Percent  Shareholder"  shall mean any  Employee  who, at the
               time of the grant of an Option,  owns (or is deemed to own, under
               Section  424(d) of the Code)  more than ten  percent of the total
               combined voting power of all classes of outstanding  stock of the
               Corporation.

     3.  Effective Date. This Plan was approved by the Board effective March 21,
1991.

     4.   Administration. This Plan shall be administered by the Board or by the
Committee. A majority of the Committee,  but in no case less than two members of
such Committee,  shall constitute a quorum for the transaction of business.  The
Board or Committee shall from time to time at its discretion make determinations
with respect to the persons who shall be granted  Options,  the number of Shares
to be optioned to each and the  designation  of such Options as Incentive  Stock
Options or Non-statutory  Stock Options.  The interpretation and construction by
the  Board or the  Committee  of any  provisions  of the  Plan or of any  Option
granted thereunder shall be binding and conclusive on all Optionees and of their
legal representatives and beneficiaries.

     5.   Eligibility. Any Employee may be granted Incentive Stock Options under
the Plan and any Employee or officer,  director or consultant of the Corporation
may be granted  Non-Statutory Stock Options under the Plan if, in each instance,
the Board or Committee  determines that such person performs services of special
importance to the  management,  operation and development of the business of the
Corporation.

     6.   Stock.  The stock  subject to Options  granted under the Plan shall be
Shares of  authorized  but unissued or reacquired  Common  Stock.  The aggregate
number of Shares which may be issued under Options exercised under this Plan


                                      E-3
<PAGE>


shall  not  exceed  2,813,765(2).  The  number  of  Shares  subject  to  Options
outstanding  under  the Plan at any time may not  exceed  the  number  of Shares
remaining  available  for issuance  under the Plan. In the event that any Option
outstanding  under the Plan expires for any reason or is terminated,  the Shares
allocable to the unexercised portion of such Option may again be subjected to an
Option under the Plan.

     The  limitations  established  by  this  Section  6  shall  be  subject  to
adjustment  upon  the  occurrence  of the  events  specified  and in the  manner
provided in Section 10 hereof.

     7.   Terms and Conditions of Options. Options granted  pursuant to the Plan
shall be  evidenced  by  written  agreements  in such  form as the  Board or the
Committee shall from time to time determine,  which agreements shall comply with
and be subject to the following terms and conditions:

          a. Date of Grant.  Each Option shall specify its  effective  date (the
     "Date  of  Grant"),  which  shall  be the date  specified  by the  Board or
     Committee in its action relating to the grant of the Option.

          b. Number of Shares.  Each Option  shall state the number of Shares to
     which  it  pertains  and  shall  provide  for  the  adjustment  thereof  in
     accordance with the provisions of Section 10 hereof.

          c. Exercise Price.  Each Option shall state the Exercise Price,  which
     price shall be determined by the Board or Committee, provided however, that
     the Exercise Price (i) in the case of an Incentive  Stock Option granted to
     an Employee  who is not a Ten Percent  Shareholder,  shall not be less than
     the par value nor less than the Fair  Market  Value of the  Shares to which
     the Option  relates on the date of grant,  (ii) in the case of an Incentive
     Stock Option granted to an Employee who is a Ten Percent Shareholder, shall
     not be less than the par value nor less than 110% of the Fair Market  Value
     of the Shares to which the Option  relates on the date of grant,  and (iii)
     in the case of a  Non-statutory  Stock  Option  granted to any  Employee or
     officer  or  director  of the  Corporation,  shall not be less than the par
     value of the Shares to which the Option  relates.  The Exercise Price of an
     Option shall be subject to adjustment in accordance with Section 10 hereof.

          d. Exercise of Options and Medium and Time of Payment.  To exercise an
     Option,  the Optionee shall give written  notice to the Company  specifying
     the number of Shares to be purchased and  accompanied by payment in cash or
     by certified check of the full Purchase Price therefor or such other method
     as permitted

- ----------
(2)  This reflects 3.4 - for - 1 reverse stock split effected in June 1991.


                                      E-4
<PAGE>


     by the Board or the Committee.  No Share shall be issued until full payment
     therefor has been made.

          e. Term and  Exercise  of  Options;  Non-transferability  of  Options.
     Incentive  Options  are  not  exercisable  for a  period  of one  (1)  year
     following  the date of grant.  Thereafter,  subject  to  Section 10 hereof,
     Incentive Options and Non-statutory  Options may be exercised as determined
     by the Board or Committee and as stated in the written agreement evidencing
     the Option, provided, however, that no Incentive Stock Option granted to an
     Employee who is not a Ten Percent  Shareholder  shall be exercisable  after
     the  expiration  of ten (10)  years  from the  date it is  granted,  and no
     Incentive  Stock  Option  granted  to an  Employee  who  is a  Ten  Percent
     Shareholder  shall be  exercisable  after the  expiration of five (5) years
     from the date it is  granted.  During the  lifetime  of the  Optionee,  the
     Option  shall  be  exercisable  only  by  the  Optionee  and  shall  not be
     assignable or transferable. In the event of the Optionee's death, no Option
     shall be transferable by the Optionee otherwise than by will or by the laws
     of descent and distribution.

          f.  Termination  of  Employment.  In the event that an Optionee  shall
     cease to be employed by the Corporation  for any reason,  such Optionee (or
     the heirs or  legatees  of such  Optionee,  if  applicable)  shall have the
     right,  subject to the  restrictions of Subsection (e) hereof,  to exercise
     the Option at any time within  three (3) months after such  termination  of
     employment  (twelve (12) months if the  termination was due to the death or
     Disability of the Optionee or, in the case of a Non-statutory Stock Option,
     retirement)  or any  other  time  period  determined  by the  Board  or the
     Committee to the extent that, on the day preceding the date of  termination
     of  employment,  the  Optionee's  right to exercise such Option had accrued
     pursuant to the terms of the option agreement pursuant to which such Option
     was granted,  and had not previously been exercised;  provided that in case
     of a  Non-statutory  Stock  Option,  the right to exercise  the option will
     terminate  immediately  upon  termination of the Optionee's  employment for
     cause.

          For this  purpose,  the  employment  relationship  will be  treated as
     continuing  intact while the Optionee is on military  leave,  sick leave or
     other bona fide leave of absence (to be determined  in the sole  discretion
     of the Board and, in the case of an Optionee  who has received an Incentive
     Stock Option,  only to the extent  permitted  under Section 422 of the Code
     and the regulations  promulgated  thereunder).  Moreover, in the case of an
     Optionee who has been granted an Incentive Stock Option,  employment shall,
     in no event,  be deemed to continue  beyond the ninetieth  (90th) day after
     the Optionee ceased active employment,  unless the Optionee's  reemployment
     rights are guaranteed by statute or by contract.

          g. Rights as a Shareholder.  An Optionee or a transferee of a deceased
     Optionee  shall have no rights as a shareholder  with respect to any Shares
     covered  by his or her  Option  until the date of the  issuance  of a stock
     certificate for


                                      E-5
<PAGE>


     such  Shares.  No  adjustment  shall be made  for  dividends  (ordinary  or
     extraordinary,   whether  in  cash,   securities  or  other   property)  or
     distributions  or other  rights for which the  record  date is prior to the
     date such stock certificate is issued, except as provided in Section 10.

          h.  Modification,  Extension  and Renewal of  Options.  Subject to the
     terms and conditions  and within the  limitations of the Plan, the Board or
     Committee may modify, extend or renew outstanding Options granted under the
     Plan,  or accept the  exchange  of  outstanding  Options (to the extent not
     theretofore  exercised)  for the  granting of new  Options in  substitution
     therefor.  Notwithstanding  the foregoing,  however,  no modification of an
     Option  shall,  without  the consent of the  Optionee,  alter or impair any
     rights or obligations under any Option theretofore  granted under the Plan.
     Moreover,  in the case of any  modification,  extension  or  renewal  of an
     Incentive  Stock  Option,  all of the  requirements  set forth herein shall
     apply in the same manner as though a new  Incentive  Stock  Option had been
     granted to the  Optionee  on the date of such  modification,  extension  or
     renewal,  but only if such  modification,  extension or renewal is treated,
     under Section 424(h) of the Code, as the granting of a new option.

          i.  Identification of Option. Each Option granted under the Plan shall
     clearly  identify its status as an Incentive Stock Option or  Non-Statutory
     Stock Option.

          j. Other Provisions.  The option agreements  authorized under the Plan
     shall contain such other provisions not inconsistent  with the terms of the
     Plan, including, without limitation,  restrictions upon the exercise of the
     Option, as the Board or Committee shall deem advisable.

     8.   Limitation on Annual Awards.

     General  Rule.  To the extent  required  to qualify as an  Incentive  Stock
Option the  aggregate  Fair Market Value  (determined  at the time the Option is
granted) of stock for which  Incentive  Stock  Options are  exercisable  for the
first time during any  calendar  year under the terms of the Plan (and all other
plans  maintained by the corporation and its parent or subsidiary  corporations)
shall not exceed the sum of $100,000.

     9.   Term of Plan. Options may be  granted  pursuant  to the Plan until ten
(10) years from the date that the Plan is adopted by the Board or ten (10) years
from the date that the Plan is  approved  by the  shareholders  of the  Company,
whichever occurs earlier.

     10.  Recapitalization.  Subject to any required action by the  shareholders
and the last sentence of subsection 7(h) hereof, the number of Shares covered by
this


                                      E-6
<PAGE>


Plan as provided in Section 6, the number of shares covered by each  outstanding
Option, and the Exercise Price thereof shall be proportionately adjusted for any
increase or decrease in the number of issued Shares resulting from a subdivision
or consolidation of Shares, stock split, or the payment of a stock dividend.

     Subject to any required  action by the  shareholders of the Company and the
last sentence of Subsection  7(h) hereof,  if the Company shall be the surviving
corporation  in any  merger or  consolidation,  each  outstanding  Option  shall
pertain  and apply to the  securities  to which a holder of the number of Shares
subject to the Option would have been entitled.  A dissolution or liquidation of
the  Company  or a merger  or  consolidation  in which  the  Company  is not the
surviving  corporation shall cause each outstanding Option to terminate,  unless
the agreement of merger or consolidation shall otherwise provide;  provided that
each Optionee shall,  in such event,  have the right  immediately  prior to such
dissolution or liquidation,  or merger or  consolidation in which the Company is
not the surviving corporation,  if a period of one (1) year from the date of the
grant of the Option  shall have  elapsed,  to exercise the Option in whole or in
part,  whether or not the Optionee's right to exercise such option has otherwise
accrued  pursuant  to the terms of the option  agreement  pursuant to which such
option was granted,  subject to  limitations  on  exercisability  imposed by the
Board or Committee  and  contained in the option  agreement in  accordance  with
Section 7(j) hereof.  The Board or the  Committee  shall have the right to waive
such one (1) year period.

     In the  event of a change in the  common  Stock as  presently  constituted,
which is limited to a change of all of its authorized shares with par value into
the same number of shares with a different  par value or without par value,  the
shares  resulting  from any such  change  shall be deemed to be Shares of Common
stock within the meaning of the Plan.

     To the extent that the foregoing  adjustments relate to stock or securities
of the Company, such adjustments shall be made by the Board or Committee,  whose
determination in that respect shall be final, binding and conclusive.

     Except as hereinbefore  expressly provided in this Section 10, the Optionee
shall have no rights by reason of any subdivision or  consolidation of shares of
stock of any class,  stock  split,  or the payment of any stock  dividend or any
other  increase  or decrease in the number of shares of stock of any class or by
reason of any dissolution,  liquidation, merger, or consolidation or spin-off of
assets or stock of  another  corporation,  and any  issuance  by the  Company of
shares of stock of any class or securities  convertible  into shares of stock of
any class,  shall not affect,  and no adjustment by reason thereof shall be made
with respect to, the number or price of Shares subject to the Option.


                                      E-7
<PAGE>


     The grant of an Option pursuant to the Plan shall not affect in any way the
right  or  power  of  the  Company  to  make   adjustments,   reclassifications,
reorganizations  or changes of its capital or business  structure or to merge or
consolidate or to dissolve,  liquidate,  sell or transfer all or any part of its
business or assets.

     11.  Securities  Law  Requirements.  No  Shares  shall be  issued  upon the
exercise of any Option unless and until the Company has determined  that: (i) it
and the  Optionee  have taken all actions  required to register the Shares under
the  Securities  Act of 1933 or  perfect  an  exemption  from  the  registration
requirements  thereof;  (ii) any  applicable  listing  requirement  of any stock
exchange on which the Common Stock is listed has been  satisfied;  and (iii) any
other applicable provision of state or Federal law has been satisfied.

     12.  Amendment of the Plan.  Subject to the last  paragraph of this Section
12 and insofar as permitted by law, the Board or Committee, may, by  resolution,
from  time to time,  with  respect  to any  Shares  at the time not  subject  to
Options,  suspend or  discontinue  the Plan or revise or amend it in any respect
whatsoever.

     No such amendment will require  stockholder  approval,  unless  stockholder
approval is  required by either the rules of Nasdaq or any other stock  exchange
upon which the Corporation's securities shall be listed or any applicable law.

     13.  Application  of Funds.  The proceeds  received by the Company from the
sale of Common  Stock  pursuant  to the  exercise  of an Option will be used for
general corporate purposes.

     14.  No Obligation  to Exercise  Option.  The  granting of an Option  shall
impose no obligation upon the Optionee to exercise such Option.

     15.  Withholding.

          (a)  Non-Statutory  Options.  Whenever Shares are to be delivered upon
     exercise of a Non-Statutory  Option,  the Corporation  shall be entitled to
     require  as a  condition  of  delivery  that  the  Optionee  remit  to  the
     Corporation  an amount  sufficient  to satisfy the  Corporation's  federal,
     state and local withholding tax obligations with respect to the exercise of
     the Option.

          (b) Incentive Stock Options. The acceptance of Shares upon exercise of
     an Incentive  Stock Option  shall  constitute  an agreement by the Optionee
     (unless and until the  Corporation  shall  notify the  Optionee  that it is
     relieved,  in whole or in part, of its obligations under Section 15(b)) (i)
     to


                                      E-8
<PAGE>


     notify the  Corporation if any or all of such Shares are disposed of within
     one (1) year from the date the  Shares  were  transferred  to the  Optionee
     pursuant  to  his  exercise  of  the  Option,  and  (ii)  to  remit  to the
     Corporation,  at the time of and in the case of any  such  disposition,  an
     amount  sufficient to satisfy the  Corporation's  federal,  state and local
     withholding tax obligations  with respect to such  disposition,  whether or
     not,  as to  both  (i) and  (ii),  the  Optionee  is in the  employ  of the
     Corporation at the time of such disposition.

     16.  Governing  Law.  The  provisions  of this Plan shall be  governed  and
construed  in  accordance  with the laws of the State of New  Jersey;  provided,
however,  that in the  case of the  provisions  applicable  to  Incentive  Stock
Options, such provisions shall (to the extent possible) be construed in a manner
conforming to and consistent with the requirements of Section 422 of the Code.


                                      E-9


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