OSTEOTECH INC
4, 1998-10-08
MISC HEALTH & ALLIED SERVICES, NEC
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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                     FORM 4

                  STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

     Filed  pursuant to Section  16(a) of the  Securities  Exchange Act of 1934,
       Section 17(a) of the Public Utility Holding Company Act of 1935 or
               Section 30(f) of the Investment Company Act of 1940

[_]  Check box if no longer  subject of Section 16. Form 4 or Form 5 obligations
     may continue. See Instruction 1(b).

- --------------------------------------------------------------------------------
1.   Name and Address of Reporting Person*

     Bauer                       Richard               W.          
- --------------------------------------------------------------------------------
   (Last)                           (First)             (Middle)
          c/o Osteotech, Inc.
          51 James Way   
- --------------------------------------------------------------------------------
                                    (Street)

     Eatontown                  New Jersey             07724
- --------------------------------------------------------------------------------
   (City)                           (State)              (Zip)


- --------------------------------------------------------------------------------
2.   Issuer Name and Ticker or Trading Symbol

     Osteotech, Inc. (OSTE)

- --------------------------------------------------------------------------------
3.   IRS Identification Number of Reporting Person, if an Entity (Voluntary)



- --------------------------------------------------------------------------------
4.   Statement for Month/Year

     September 1998

- --------------------------------------------------------------------------------
5.   If Amendment, Date of Original (Month/Year)


================================================================================
6.   Relationship of Reporting Person to Issuer
     (Check all applicable)

     [X]  Director                             [_]  10% Owner
     [X]  Officer (give title below)           [_]  Other (specify below)

               President and
               Chief Executive Officer 
- --------------------------------------------------------------------------------
7. Individual or Joint/Group Filing (Check applicable line)

     [X]  Form filed by one Reporting Person
     [_]  Form filed by more than one Reporting Person
- --------------------------------------------------------------------------------


================================================================================
           Table I -- Non-Derivative Securities Acquired, Disposed of,
                             or Beneficially Owned
================================================================================
<TABLE>
<CAPTION>
                                                                                                                6.
                                                                 4.                              5.             Owner-
                                                                 Securities Acquired (A) or      Amount of      ship
                                                    3.           Disposed of (D)                 Securities     Form:     7.
                                                    Transaction  (Instr. 3, 4 and 5)             Beneficially   Direct    Nature of
                                      2.            Code         ------------------------------- Owned at End   (D) or    Indirect
1.                                    Transaction   (Instr. 8)                   (A)             of Month       Indirect  Beneficial
Title of Security                     Date          ------------     Amount      or     Price    (Instr. 3      (I)       Ownership
(Instr. 3)                            (mm/dd/yy)     Code     V                  (D)             and 4)         (Instr.4) (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                                   <C>            <C>      <C>    <C>         <C>    <C>         <C>            <C>       <C>


- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/16/98        M               29,382      A      $ 4.250      
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/16/98        M               41,667      A      $ 4.250  
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/16/98        M                3,951      A      $ 4.250       
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/16/98        S               75,000      D      $25.000
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/28/98        M               37,716      A      $ 4.250
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/28/98        M               12,284      A      $ 4.250
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/28/98        S               45,000      D      $29.000 
- ------------------------------------------------------------------------------------------------------------------------------------
Common Stock                          9/28/98        S                5,000      D      $29.0625    14,320         D         -
- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

====================================================================================================================================
</TABLE>

Reminder: Report on a separate line for each class of securities beneficially
          owned directly or indirectly.

                            (Print or Type Responses)
                                                                          (Over)
(Form 4-07/98)

<PAGE>


FORM 4 (continued)

Table    II --  Derivative  Securities  Acquired,  Disposed of, or  Beneficially
         Owned (e.g., puts, calls, warrants, options, convertible securities)

================================================================================
<TABLE>
<CAPTION>
                                                                                                                    10.     
                                                                                                          9.        Owner-  
                                                                                                          Number    ship    
                                                                                                          of        Form
                    2.                                                                                    Deriv-    of     
                    Conver-                    5.                              7.                         ative     Deriv-   11.    
                    sion                       Number of                       Title and Amount           Secur-    ative    Nature 
                    or                         Derivative    6.                of Underlying     8.       ities     Secur-   of     
                    Exer-             4.       Securities    Date              Securities        Price    Bene-     ity:     In-    
                    cise     3.       Trans-   Acquired (A)  Exercisable and   (Instr. 3 and 4)  of       ficially  Direct   direct 
                    Price    Trans-   action   or Disposed   Expiration Date   ----------------  Deriv-   Owned     (D) or   Bene-  
1.                  of       action   Code     of(D)         (Month/Day/Year)            Amount  ative    at End    In-      ficial 
Title of            Deriv-   Date     (Instr.  (Instr. 3,    ----------------            or      Secur-   of        direct   Owner- 
Derivative          ative    (Month/  8)       4 and 5)      Date     Expira-            Number  ity      Month     (I)      ship   
Security            Secur-   Day/     ------   ------------  Exer-    tion               of      (Instr.  (Instr.   (Instr.  (Instr.
(Instr. 3)          ity      Year)    Code V    (A)   (D)    cisable  Date     Title     Shares  5)       4)        4)       4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                 <C>      <C>      <C>  <C>  <C>   <C>    <C>      <C>      <C>       <C>     <C>      <C>       <C>      <C>


- ------------------------------------------------------------------------------------------------------------------------------------
Employee Stock 
Option (a)                                                                     Common    
(Right to Buy)      $4.250   9/16/98  M              29,382  2/14/95  02/14/00  Stock    29,382           --         D
- ------------------------------------------------------------------------------------------------------------------------------------
Employee Stock 
Option (a)                                                                     Common    
(Right to Buy)      $4.250   9/16/98  M              41,667  02/14/96 02/14/01  Stock    41,667           --         D
- ------------------------------------------------------------------------------------------------------------------------------------
Employee Stock
Option (a)                                                                     Common
(Right to buy)      $4.250   9/16/98  M               3,951  02/14/97 02/14/02  Stock     3,951           --        D
- ------------------------------------------------------------------------------------------------------------------------------------
Employee Stock
Option (a)                                                                     Common 
(Right to buy)      $4.250   9/28/98   M              37,716  02/14/97 02/14/02 Stock     37,716           --        D
- ------------------------------------------------------------------------------------------------------------------------------------
Employee Stock 
Option (a)                                                                     Common
(Right to buy)      $4.250   9/28/98   M              12,284  02/14/98 02/14/03 Stock     12,284           29,432    D
- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

====================================================================================================================================
</TABLE>
Explanation of Responses:


/s/ Richard W. Bauer                                         October 6, 1998
- ---------------------------------------------            -----------------------
      **Signature of Reporting Person                             Date

        Richard W. Bauer

(a)    Granted under the Company's 1991 Stock Option Plan and qualified under 
       Rule 16b-3  

**     Intentional misstatements or omissions of facts constitute Federal 
       Criminal Violations.

       See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:  File three copies of this Form, one of which must be manually signed.
       If space provided is insufficient, see Instruction 6 for procedure.


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