OSTEOTECH INC
10-Q, 1999-11-15
MISC HEALTH & ALLIED SERVICES, NEC
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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549


                                    FORM 10-Q


                                   (Mark One)

[x] Quarterly Report Pursuant to Section 13 or 15(d) of the Securities  Exchange
Act of 1934 For the Period Ended September 30, 1999

                                       or

[ ] Transition Report Pursuant to Section 13 or 15(d) of the Securities Exchange
Act of 1934 For the Transition Period from ___________ to __________


Commission File Number 0-19278


                                 OSTEOTECH, INC.
             (Exact name of registrant as specified in its charter)

                     Delaware                                 13-3357370
        (State or other jurisdiction of                    (I.R.S. Employer
         incorporation or organization)                    Identification No.)

      51 James Way, Eatontown, New Jersey                         07724
    (Address of principal executive offices)                   (Zip Code)

                                  (732)542-2800
              (Registrant's telephone number, including area code)

                                 Not Applicable
(Former  name,  former  address and former  fiscal year,  if changed  since last
report)

Indicate by check mark whether the registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  registrant  was
required  to file  such  reports),  and  (2) has  been  subject  to such  filing
requirements for the past 90 days.

Yes [X]   No [_]

                      Applicable Only to Corporate Issuers

Indicate the number of shares  outstanding  of each of the  issuer's  classes of
common stock, as of the latest practical date.

Common Stock, $.01 par value - 14,184,684 shares as of October 31, 1999.


<PAGE>


PART I.  FINANCIAL INFORMATION
ITEM 1.  Financial Statements


                        OSTEOTECH, INC. AND SUBSIDIARIES
                      CONDENSED CONSOLIDATED BALANCE SHEETS
                                   (unaudited)
                             (dollars in thousands)

<TABLE>
<CAPTION>
                                                            September 30,  December 31,
                                                                 1999          1998
- ---------------------------------------------------------------------------------------
<S>                                                            <C>             <C>
ASSETS
- ---------------------------------------------------------------------------------------
Current assets:
     Cash and cash equivalents                                 $ 17,258        $ 15,119
     Short-term investments                                       3,946           2,922
     Accounts receivable, net                                    10,920          11,980
     Inventories                                                  3,547           1,568
     Deferred processing cost                                     4,724           2,620
     Prepaid expenses and other current assets                    2,748           2,913
     Litigation settlement receivable                             2,000
                                                               ------------------------
        Total current assets                                     45,143          37,122

Property, plant and equipment, net                               29,014          16,044
Excess of cost over net assets of business acquired,
     less accumulated amortization of $1,991 in 1999 and
     $1,701 in 1998                                               3,780           1,997
Other assets                                                      1,833           1,951
- ---------------------------------------------------------------------------------------
Total assets                                                   $ 79,770        $ 57,114
=======================================================================================

LIABILITIES AND STOCKHOLDERS' EQUITY
- ---------------------------------------------------------------------------------------
Current liabilities:
     Accounts payable and accrued liabilities                  $ 11,804        $  9,935
     Notes payable                                                  101             609
     Current maturities of long-term debt and
         obligations under capital leases                                           205
                                                               ------------------------
        Total current liabilities                                11,905          10,749

Long-term debt                                                    3,624
Other liabilities                                                   435             435
- ---------------------------------------------------------------------------------------
Total liabilities                                                15,964          11,184
- ---------------------------------------------------------------------------------------

Commitments and contingencies

Stockholders' equity:
     Preferred stock, $.01 par value; 5,676,595 shares
         authorized; no shares issued or outstanding
     Common stock, $.01 par value; 70,000,000 shares
         authorized; issued and outstanding 14,184,609
         shares in 1999 and 13,380,291 shares in 1998               140             133
     Additional paid-in capital                                  45,544          37,332
     Accumulated other comprehensive income (loss)                  (82)             11
     Retained earnings                                           18,204           8,454
- ---------------------------------------------------------------------------------------
Total stockholders' equity                                       63,806          45,930
- ---------------------------------------------------------------------------------------
Total liabilities and stockholders' equity                     $ 79,770        $ 57,114
=======================================================================================
</TABLE>

See accompanying notes to condensed consolidated financial statements.


                                       2
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
                 CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
                                   (unaudited)
                  (dollars in thousands, except per share data)


<TABLE>
<CAPTION>
                                                               Three Months                       Nine Months
                                                           Ended September 30,                Ended September 30,
                                                     -----------------------------       -----------------------------
                                                            1999              1998              1999              1998
- ----------------------------------------------------------------------------------------------------------------------
<S>                                                  <C>               <C>               <C>               <C>
Net revenues:
   Service                                           $    16,770       $    14,001       $    53,596       $    42,085
   Product                                                   699               282             2,163               803
   License fee                                                                                   118               124
                                                     -----------       -----------       -----------       -----------
                                                          17,469            14,283            55,877            43,012

Cost of services                                           5,204             3,910            16,330            12,424
Cost of products                                             439               232             1,285               584
                                                     -----------       -----------       -----------       -----------
                                                           5,643             4,142            17,615            13,008
                                                     -----------       -----------       -----------       -----------

Gross Profit                                              11,826            10,141            38,262            30,004

Marketing, general and administrative                      6,956             4,851            20,019            15,432
Research and development                                   1,310             1,079             4,248             3,285
                                                     -----------       -----------       -----------       -----------
                                                           8,266             5,930            24,267            18,717

Income from litigation settlement                          1,750                               1,750
                                                     -----------       -----------       -----------       -----------

Operating income                                           5,310             4,211            15,745            11,287

Interest and other income, net                               208               285               636               886
                                                     -----------       -----------       -----------       -----------

Income before income taxes                                 5,518             4,496            16,381            12,173

Income tax provision                                       2,270             1,878             6,631             5,020

- ----------------------------------------------------------------------------------------------------------------------
Net income                                           $     3,248       $     2,618       $     9,750       $     7,153
======================================================================================================================
Net income per share:
     Basic                                           $       .23       $       .20       $       .70       $       .54
     Diluted                                         $       .22       $       .19       $       .67       $       .51
- ----------------------------------------------------------------------------------------------------------------------
Shares used in computing net income per share:
     Basic                                            14,174,402        13,168,880        13,969,901        13,225,814
     Diluted                                          14,641,259        13,958,635        14,639,183        14,067,937
</TABLE>


See accompanying notes to condensed consolidated financial statements.


                                       3
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
                 CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
                                   (unaudited)
                             (dollars in thousands)

<TABLE>
<CAPTION>
Nine Months Ended September 30,                                  1999            1998
- ---------------------------------------------------------------------------------------
<S>                                                            <C>             <C>
Cash Flow From Operating Activities
   Net income                                                  $  9,750        $  7,153
   Adjustments to reconcile net income to net cash
      Provided by (used in) operating activities:
         Depreciation and amortization                            2,201           2,042
         Changes in assets and liabilities:
               Accounts receivable                                1,403            (624)
               Inventories                                       (1,451)           (467)
               Deferred processing costs                         (2,104)           (865)
               Prepaid expenses and other current assets            396           2,083
               Litigation settlement receivable                  (2,000)
               Accounts payable and other liabilities               913              68
- ---------------------------------------------------------------------------------------
Net cash provided by operating activities                         9,108           9,390

Cash Flow From Investing Activities
   Capital expenditures                                         (13,537)         (4,326)
   Purchases of investments                                     (11,634)         (7,387)
   Proceeds from sale of investments                             10,610           5,941
   Acquisition of business                                       (1,526)
   Increase in other assets                                        (859)           (746)
- ---------------------------------------------------------------------------------------
Net cash used in investing activities                           (16,946)         (6,518)

Cash Flow From Financing Activities
   Proceeds from issuance of common stock                         4,854           2,756
   Income tax benefit related to stock options                    3,365           2,870
   Repurchase of common stock                                                    (4,958)
   Proceeds from issuance of notes payable                          116
   Principal payments on notes payable                             (693)           (582)
   Proceeds from long-term debt                                   3,000
   Principal payments on long-term debt
      And obligations under capital leases                         (758)           (482)
   Increase in other liabilities                                    171
- ---------------------------------------------------------------------------------------
Net cash (used in) provided by financing activities              10,055            (396)

Effect of exchange rate changes on cash                             (78)             74
- ---------------------------------------------------------------------------------------

Net increase in cash and cash equivalents                         2,139           2,550
Cash and cash equivalents at beginning of period                 15,119          13,884
- ---------------------------------------------------------------------------------------
Cash and cash equivalents at end of period                     $ 17,258        $ 16,434
=======================================================================================

Supplementary cash flow data:
   Cash paid during the period for interest                    $     29        $     63
   Cash paid during the period for taxes                          2,114           1,065
   Acquisition of business:
      Fair value of assets acquired                               2,563
      Liabilities assumed                                         2,669
</TABLE>


See accompanying notes to condensed consolidated financial statements.


                                       4
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


1.   Basis of Presentation

     The accompanying  unaudited  condensed  consolidated  financial  statements
     reflect all  adjustments  (consisting  only of normal  recurring  accruals)
     considered   necessary  by  management  to  present  fairly  the  Company's
     consolidated  financial  position as of September 30, 1999 and December 31,
     1998, and the  consolidated  results of operations for the  three-month and
     nine-month  periods ended September 30, 1999 and 1998, and the consolidated
     cash flows for the nine-month periods then ended. The results of operations
     for the respective  interim periods are not  necessarily  indicative of the
     results  to be  expected  for the full  year.  The  condensed  consolidated
     financial  statements  should  be  read in  conjunction  with  the  audited
     financial  statements  for the year  ended  December  31,  1998  which were
     included as part of the Company's Report on Form 10-K.

2.   Stockholders' Equity

     In February,  1999, the Board of Directors authorized a three-for-two stock
     split in the form of a 50% stock dividend that was  distributed in March to
     stockholders  of record on March 5,  1999.  Stockholders'  equity  has been
     restated to give retroactive recognition to the stock split for all periods
     presented.  In addition,  all  references  in the  financial  statements to
     shares, per share data, and stock option data have been restated.

     In June, 1999, the Stockholders of the Company approved an amendment to the
     Company's certificate of incorporation to increase the number of authorized
     shares of common stock to 70,000,000 shares.

3.   Acquisition of OST Developpement SA

     Effective  January 1, 1999, the Company  completed the acquisition of a 90%
     interest in OST Developpement SA ("OST"), a processor of bovine bone grafts
     for orthopaedic and dental use. The aggregate purchase price paid consisted
     solely  of  cash  consideration  of  9,000,000  French  Francs  ("FRF")  or
     approximately  $1,594,700.  In addition, the Company incurred approximately
     $372,600 of  transaction  costs.  The  acquisition  was  accounted for as a
     purchase and the consolidated  financial statements include the accounts of
     OST from  January 1, 1999.  The  acquisition  resulted in an excess of cost
     over the fair value of net assets  acquired  of  $2,073,000  which is being
     amortized  over 15 years.  The Company  also has the option to purchase the
     remaining 10% of OST at a price to be determined at the time of purchase.

4.   Acquisition of Spinal Fixation System

     In June,  1999,  the Company  acquired the  Versalok(R)  Low Back  Fixation
     System (the  "Versalok(R)  System"),  including  all  patents,  from Wright
     Medical  Technology,  Inc.  for  $600,000.  Pursuant  to the  terms  of the
     purchase  agreement,  the Company  also  agreed to  purchase  approximately
     $1,120,000 of



                                       5
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


4.   Acquisition of Spinal Fixation System - continued

     inventory,  consisting primarily of finished goods. The $600,000 payment to
     acquire  the  product  rights  and  patents  will be  amortized  using  the
     straight-line basis over five years.

5.   Comprehensive Income

     Comprehensive  income for the  three-month  and  nine-month  periods  ended
     September 30, 1999 and 1998:

<TABLE>
<CAPTION>
                                                   Three months ended            Nine months ended
                                                      September 30,                September 30,
                                                 ----------------------------------------------------

        (dollars in thousands)                    1999          1998         1999          1998
        ---------------------------------------------------------------------------------------------
<S>                                               <C>          <C>          <C>           <C>
        Net income                                $3,248       $2,618       $9,750        $7,153

        Currency translation adjustments             189           83           (93)          84
        ---------------------------------------------------------------------------------------------

        Comprehensive Income                      $3,437       $2,701       $9,657        $7,237
        =============================================================================================
</TABLE>


6.   Financing Arrangements

     In June, 1999, the Company replaced its domestic lines of credit with a new
     credit  facility  which includes a $5,000,000  unsecured  revolving line of
     credit,  a $4,500,000  building  mortgage loan and a $17,000,000  equipment
     line of credit.  The revolving line of credit is committed  through May 31,
     2001. In the absence of default,  the Company has the option to convert the
     revolving line of credit to a term-loan and the outstanding  unpaid balance
     as of  May  31,  2001  will  be  repayable  in  forty-eight  equal  monthly
     installments  of  principal  together  with  accrued  interest.  An  unused
     facility  fee of .25% is  payable on the  unused  portion of the  revolving
     loan. The mortgage loan will be drawn down upon completion of the Company's
     new allograft tissue processing  facility  currently under construction and
     will be  secured  by the  building  which  will  house  the new  processing
     facility and the land on which the building is located.  The mortgage  loan
     will be  repayable  in 120 equal  monthly  installments  of  principal  and
     interest based on a twenty-year mortgage  amortization  schedule.  Upon the
     120th  payment,  the full  amount of the unpaid  principal  will be due and
     payable.  The  equipment  line of credit is secured by equipment  and other
     capital  expenditures  purchased  using the  proceeds  of such  line,  with
     advances of up to 80% of the cost  thereof.  Upon  expiration of an initial
     drawdown period, which expires December, 2000, the equipment line of credit
     will be repayable in equal monthly  installments  of principal and interest
     based on a seven-year  amortization  schedule.  During the drawdown  period
     interest only will be payable under the equipment line of credit.


                                       6
<PAGE>


                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


6.   Financing Arrangements - continued

     Pursuant to the terms of the loan and security agreement (the "Agreement"),
     the Company is  required  to meet  certain  financial  covenants  regarding
     minimum  working  capital,  tangible  net worth and interest  coverage.  In
     addition,  the Agreement contains limitations on sales of assets other than
     in  the  ordinary  course  of  business  and  additional  indebtedness.  At
     September 30, 1999,  there was $3,000,000  outstanding  under the revolving
     line of credit.

7.   Commitments and Contingencies

     Product Liability Litigation

     The Company is a defendant in two state court product  liability actions in
     which patients claim that they have suffered  damages from the implantation
     of orthopaedic bone screws allegedly distributed by the Company. One of the
     actions is stayed.  In  September,  1999,  plaintiffs in one of the actions
     voluntarily  dismissed the Company without prejudice.  Management  believes
     that the  remaining  lawsuit and claims are without merit and will continue
     to defend such action vigorously.  It is the Company's position that either
     a device  distributed  by the Company was not implanted in the patient,  or
     that if the  allegations in the complaints  regarding the use of the device
     are assumed to be true,  the device was used in a manner which was contrary
     to  the  use  approved  by the  FDA  and  the  Company's  written  warnings
     concerning use.  Pursuant to its  distribution  agreement with the Company,
     the  manufacturer of the spinal fixation  devices,  Heinrich C. Ulrich,  KG
     ("Ulrich")  has agreed to indemnify the Company for all costs,  and damages
     incurred by the Company in  connection  with its  distribution  of products
     manufactured  by Ulrich,  except such costs and damages which are caused by
     the Company's gross negligence,  willful  misconduct or unauthorized  claim
     made by the Company in marketing the products.

     In July,  1998,  a  complaint  was filed  against the Company in the Second
     Judicial  District  Court,  Bernallilo  County,  New Mexico,  which alleges
     negligence,    strict    liability,    breach   of   warranty,    negligent
     misrepresentation,  fraud,  and  violation  of the New Mexico  Unfair Trade
     Practices Act arising from allegedly  defective  dental implant coating and
     coating services provided to plaintiffs by a subsidiary of the Company, Cam
     Implants BV.  Plaintiffs have demanded  unspecified  monetary  damages.  In
     August, 1998, the Company removed this action to the United States District
     Court for the  District  of New Mexico  and filed and  served  its  answer,
     denying any and all liability in this action,  and moved to dismiss five of
     the seven claims alleged  against it. In November,  1998, the Company moved
     for  summary  judgment  in its favor on all of the  claims  alleged in this
     action,  on the ground that all of  plaintiffs'  claims are barred by their
     applicable  statutes of  limitations.  In March,  1999, the court dismissed
     with prejudice the plaintiff's  negligence and strict liability claims, and
     to date the Court has limited  discovery in this action to matters  related
     to the statute of limitations  issue.  The Company believes that the claims
     against it are without merit and will continue to vigorously defend against
     such claims.



                                       7
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


7.   Commitments and Contingencies - continued

     Patent Litigation

     In January,  1998, the Company filed a patent  infringement  action against
     GenSci   Regeneration   Laboratories,   Inc.  ("GenSci  Labs")  and  GenSci
     Regeneration  Sciences,  Inc. ("GenSci  Sciences") alleging that the GenSci
     parties  violated  claims of one of the  patents  involving  the  Company's
     Grafton(R) Demineralized Bone Matrix (DBM) process. Approximately two weeks
     after  Osteotech's  filing,  GenSci  Labs filed a suit  against the Company
     alleging infringement of two patents assigned to GenSci Labs in addition to
     tortious  interference with a business expectancy,  negligent  interference
     with a prospective  economic  advantage and inducing breach of contract and
     seeking a  declaratory  judgment of the  invalidity of two of the Company's
     patents covering Grafton(R) DBM. In February, 1998, GenSci Labs amended its
     complaint alleging essentially the same causes of action but adding a third
     patent to the  allegation  of patent  infringement.  The actions  have been
     consolidated  into one lawsuit.  In September,  1998, GenSci Labs served an
     amended complaint,  which asserted,  in addition to the previously asserted
     claims, claims of false advertising under Federal law. In September,  1998,
     the  Company  served  its  answer  to  this  amended  complaint,   asserted
     counterclaims  against  GenSci  Labs  and  served a  third-party  complaint
     against GenSci Sciences,  and DePuy AcroMed,  Inc.("DePuy").  The Company's
     counterclaims  and third  party  complaint  accused  the GenSci  parties of
     infringing a second Company  patent,  in addition to the patent referred to
     above,  and  accused  the DePuy and GenSci  parties of acting  jointly  and
     severally  in  infringing  on the  claims of both  patents.  Discovery  has
     commenced and is ongoing.  In May, 1999,  GenSci Labs amended its complaint
     to allege that in addition to the  Company's  Grafton(R)  DBM Flex product,
     the  Company's  Grafton(R)  DBM Gel and Putty  products  infringe on GenSci
     Lab's  patents at issue.  GenSci Labs also amended its  complaint to modify
     its false  advertising  claim,  alleging  that in addition to the  Company,
     individuals  acting on the Company's  behalf engaged in false  advertising.
     The Company  filed and served its answer and  counterclaims  to the amended
     complaint in May, 1999. In November,  1999, the Company  settled all claims
     which it had filed  against  DePuy.  As part of the  settlement,  DePuy has
     agreed to stop  selling  the  GenSci  products  accused of  infringing  the
     Company's  patents,  no later than  February 4, 2001 and to pay the Company
     $3,000,000  as  follows:  $2,000,000  in the  fourth  quarter  of 1999  and
     $250,000 at the end of each quarter in 2000. Payments in the year 2000 will
     be made unless DePuy  discontinues  selling the GenSci  products during the
     year,  at which time DePuy would not be obligated  for payments  beyond the
     quarter in which it stopped  selling the GenSci products (See Note 11). The
     Company  believes that the claims made against it by the GenSci parties are
     without merit and will continue to  vigorously  defend  against such claims
     and prosecute the claims it has asserted against the GenSci parties.


                                       8
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


7.   Commitments and Contingencies - continued

     In February,  1999, a complaint was filed against the Company in the United
     States  District Court for the Northern  District of Florida.  This action,
     which has been brought by  plaintiffs,  University of Florida  Tissue Bank,
     Inc.,  Regeneration  Technologies,  Inc.,  Sofamor Danek Group,  Inc.,  and
     Sofamor Danek L.P. alleges that Company's  bio-d(TM) threaded cortical bone
     dowel and Endodowel  infringe on the claims of U.S.  Patent No.  5,814,084,
     entitled  "Diaphysical Cortical Dowel." In April, 1999, plaintiffs filed an
     amended  complaint  adding a claim  for  patent  infringement  against  the
     Company with respect to US Patent No.  5,814,084,  entitled  "Bone Grafting
     Units", which is owned by plaintiff University of Florida Tissue Bank, Inc.
     In May,  1999,  the  Company  filed its  answer  and  counterclaim  seeking
     declaratory  judgment  that the  patents  in  question  in this  action are
     invalid and otherwise not infringed by the Company. Although the plaintiffs
     seek monetary  damages,  an amount has not been  specified.  In May,  1999,
     plaintiffs  filed their reply to the Company's  counterclaims.  The Company
     believes the claims asserted in this action to be without merit and intends
     to vigorously defend against such claims.

     In July, 1999, Medtronic Sofamor Danek Inc., Sofamor Danek L.P. and Sofamor
     Danek Holdings, Inc. ("Danek") sued Osteotech in the United States District
     Court for the Western  District of  Tennessee  alleging  that  instruments,
     instrument sets and cortical bone dowel products, including but not limited
     to the bio-d(TM) threaded cortical bone dowel and Endodowel,  manufactured,
     sold and/or otherwise distributed by the Company infringe on certain claims
     of U.S.  Patent  Nos.  5,741,253,  entitled  "Method for  Inserting  Spinal
     Implants",  and  5,484,437,  entitled  "Apparatus  and Method of  Inserting
     Spinal Implants", which are owned by Danek. In September, 1999, the Company
     filed its answer and counter  claims  seeking a declaratory  judgement that
     the  patents in question  in this  action are  invalid  and  otherwise  not
     infringed by the Company. Plaintiffs filed their reply to the counterclaims
     in October,  1999.  The Company  believes that the claims  asserted in this
     action are without  merit and intends to  vigorously  defend  against  such
     claims.

     In September,  1999,  Medtronic  Sofamor Danek,  Inc.  ("Medtronic"),  sued
     Arthur A. Alfaro,  a former  Division  President of Medtronic and currently
     the Company's  President and Chief Operating Officer, in the Chancery Court
     of Tennessee for the  Thirtieth  Judicial  District at Memphis,  seeking to
     enjoin Mr. Alfaro from divulging alleged confidential  information or trade
     secrets of  Medtronic to third  parties,  including  the Company,  and from
     working for the Company for a period of twelve months. In September,  1999,
     the Court issued a temporary  restraining order prohibiting Mr. Alfaro from
     issuing or  divulging  any  confidential  information  or trade  secrets of
     Medtronic to any third party. In October, 1999, Mr. Alfaro filed and served
     his  answer,  denying  any and all  liability.  Pursuant  to an  employment
     agreement  between Mr.  Alfaro and the  Company,  the Company is paying Mr.
     Alfaro's legal fees and costs for defending this action.


                                       9
<PAGE>


                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


7.   Commitments and Contingencies - continued

     Litigation  is subject to many  uncertainties  and  management is unable to
     predict the outcome of the pending  suits and claims.  It is possible  that
     the results of operations or liquidity and capital resources of the Company
     could  be  adversely  affected  by the  ultimate  outcome  of  the  pending
     litigation or as a result of the costs of  contesting  such  lawsuits.  The
     Company is unable to estimate the  potential  liability,  if any,  that may
     result from the pending litigation and,  accordingly,  no provision for any
     liability   (except  for  accrued   legal  costs)  has  been  made  in  the
     consolidated financial statements.

8.   Earnings Per Share

     The  following  table  sets  forth the  computation  of basic  and  diluted
     earnings  per  share  for the  three-month  and  nine-month  periods  ended
     September 30, 1999 and 1998:

<TABLE>
<CAPTION>
                                                                   Three Months Ended                    Nine Months Ended
                                                                      September 30,                        September 30,
                                                         -----------------------------------------------------------------------
         (dollars in thousands
          except per share data)                               1999              1998              1999             1998
         -----------------------------------------------------------------------------------------------------------------------
<S>                                                            <C>               <C>              <C>               <C>
         Net income available to Common                            $3,248            $2,618           $9,750            $7,153
             Shareholders
         -----------------------------------------------------------------------------------------------------------------------

         Weighted average common shares                        14,174,402        13,168,880       13,969,901        13,225,814
                                                         -----------------------------------------------------------------------
         Denominator for basic earnings per share              14,174,402        13,168,880       13,969,901        13,225,814
         Effect of dilutive securities:
             Stock options                                        466,479           789,405          669,156           842,006
             Warrants                                                 378               350              126               117
                                                         -----------------------------------------------------------------------
         Denominator for diluted earnings per
         share                                                 14,641,259        13,958,635       14,639,183        14,067,937
         -----------------------------------------------------------------------------------------------------------------------

             Basic earnings per share                                $.23              $.20             $.70              $.54
         -----------------------------------------------------------------------------------------------------------------------

             Diluted earnings per share                              $.22              $.19             $.67              $.51
         -----------------------------------------------------------------------------------------------------------------------
</TABLE>


                                       10
<PAGE>

                        OSTEOTECH, INC. AND SUBSIDIARIES
              Notes To Condensed Consolidated Financial Statements
                                   (unaudited)


9.   Operating Segments

     Summarized  in the table below is financial  information  for the Company's
     reportable  segments  for the  three-month  and  nine-month  periods  ended
     September 30, 1999 and 1998:

<TABLE>
<CAPTION>
                                                            Three Months Ended                        Nine Months Ended
                                                               September 30,                            September 30,
                                                 ----------------------------------------- -----------------------------------------
         (dollars in thousands)                         1999                 1998                 1999                 1998
         --------------------------------------- -------------------- -------------------- -------------------- --------------------
<S>                                                    <C>                   <C>                 <C>                  <C>
         Revenues:
           Grafton(R)DBM Segment                       $  9,905              $  9,802            $ 32,346             $ 28,349
           Base Tissue Segment                            6,525                 3,816              20,043               12,523
           Other                                          1,039                   665               3,488                2,140
           Consolidated                                  17,469                14,283              55,877               43,012
         --------------------------------------- -------------------- -------------------- -------------------- --------------------
         Operating income (loss):
           Grafton(R)DBM Segment                       $  4,429              $  3,712            $ 12,509             $  9,206
           Base Tissue Segment                            1,884                   829               5,969                2,901
           Other                                         (1,003)                 (330)             (2,733)               (820)
           Consolidated                                   5,310                 4,211              15,745               11,287
         --------------------------------------- -------------------- -------------------- -------------------- --------------------
</TABLE>


10.  Inventories

     Inventories consist of the following:


     (dollars in thousands)        September 30, 1999        December 31, 1998
     ---------------------------------------------------------------------------

     Raw Materials                       $   872                     $   646
     Finished Goods                        2,675                         922
     ---------------------------------------------------------------------------
                                         $ 3,547                     $ 1,568
     ---------------------------------------------------------------------------

11.  Litigation Settlement

     In November 1999, the Company settled all claims which it had filed against
     DePuy in the  patent  infringement  suit  against  GenSci  Labs and  GenSci
     Sciences  and  DePuy  (See Note 7).  As part of the  settlement,  DePuy has
     agreed to stop  selling  the  GenSci  products  accused of  infringing  the
     Company's  patents,  no later than  February 4, 2001 and to pay the Company
     $3,000,000  as  follows:  $2,000,000  in the  fourth  quarter  of 1999  and
     $250,000 at the end of each quarter in 2000. Payments in the year 2000 will
     be made unless DePuy  discontinues  selling the GenSci  products during the
     year,  at which time DePuy would not be obligated  for payments  beyond the
     quarter  in which it  stopped  selling  the GenSci  products.  The  Company
     included  $1,750,000  of the  $2,000,000  payment  in  income  in the third
     quarter of 1999 and will  recognize  the  remaining  $250,000 in the fourth
     quarter of 1999.  The  quarterly  payments  in 2000 will be  recognized  in
     income as earned.

12.  Reclassifications

     Certain  prior year amounts have been  reclassified  to conform to the 1999
     presentation.


                                       11
<PAGE>


Item 2.  MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
            CONDITION AND RESULTS OF OPERATIONS

Information contained herein contains "forward-looking  statements" which can be
identified  by the  use  of  forward-looking  terminology  such  as  "believes",
"expects",  "may", "will", "should", or "anticipates" or the negative thereof or
variations thereon or comparable terminology,  or by discussions of strategy. No
assurance can be given that the future  results  covered by the  forward-looking
statements will be achieved. Some of the matters set forth in the "Risk Factors"
section of the Company's  Annual Report on Form 10-K for the year ended December
31, 1998, constitute  cautionary statements  identifying factors with respect to
such forward-looking statements, including certain risks and uncertainties, that
could cause actual results to vary materially from the future results  indicated
in such  forward-looking  statements.  Other  factors  could also  cause  actual
results  to  vary  materially   from  the  future  results   indicated  in  such
forward-looking statements.

FOR THE THREE-MONTH AND NINE-MONTH PERIODS ENDED SEPTEMBER 30, 1999 AND 1998

Results of Operations

Litigation Settlement

In November  1999, we settled all claims which we had filed against DePuy in the
patent  infringement  suit against GenSci Labs and GenSci  Sciences (See Notes 7
and  11 of  "Notes  to  Consolidated  Financial  Statements").  As  part  of the
settlement,  DePuy has agreed to stop  selling  the GenSci  products  accused of
infringing  our patents,  no later than  February 4, 2001 and to pay the company
$3,000,000 as follows:  $2,000,000 in the fourth quarter of 1999 and $250,000 at
the end of each  quarter in 2000.  Payments in the year 2000 will be made unless
DePuy  discontinues  selling the GenSci  products during the year, at which time
DePuy would not be obligated for payments beyond the quarter in which it stopped
selling the GenSci products.  The Company included  $1,750,000 of the $2,000,000
payment in operating  income in the third quarter of 1999 and will recognize the
remaining $250,000 in the fourth quarter of 1999. The quarterly payments in 2000
will be recognized in income as earned.

Net Income

Consolidated  net income in the third quarter of 1999 increased to $3,248,000 or
$.22  diluted net income per share as compared  to net income of  $2,618,000  or
$.19 diluted net income per share in the third quarter of 1998. Consolidated net
income in the first nine months of 1999  increased to $9,750,000 or $.67 diluted
net income per share as compared to net income of $7,153,000 or $.51 diluted net
income per share in the first nine months of 1998. Net income in the quarter and
the nine  months  ended  September  30,  1999 were  positively  impacted  by the
settlement  of  the  patent   infringement  claim  against  DePuy,  which  added
$1,043,000,  after income taxes,  or $.07 diluted net income per share.  All per
share data have been adjusted for the three-for-two stock split in the form of a
50% stock dividend effected in March, 1999.

The following is a discussion of factors affecting results of operations for the
three-month and nine-month periods ended September 30, 1999 and 1998.



                                       12
<PAGE>

Net Revenues

Consolidated net revenues increased 22% to $17,469,000 from $14,283,000 in third
quarter of 1998 and increased 30% to $55,877,000  from  $43,012,000 in the first
nine months of 1998. The increase was principally due to higher revenues in both
the  Grafton(R)  Demineralized  Bone Matrix (DBM) segment ("the  Grafton(R)  DBM
segment")  and  the  Base  Allograft  Bone  Tissue  segment  (the  "Base  Tissue
segment").  Domestic  revenues,  which consist  principally of revenues from the
Grafton(R)  DBM and Base Tissue  segments,  increased  21% to  $16,672,000  from
$13,738,000  in third  quarter of 1998 and  increased  28% to  $52,810,000  from
$41,177,000 in the first nine months of 1998.  Foreign revenues increased 46% to
$797,000  from $545,000 in third quarter of 1998 and increased 67% to $3,067,000
from  $1,835,000  in the first  nine  months of 1998.  The  increase  in foreign
revenues  resulted  primarily  from the  contribution  to  revenues  made by OST
Developpement  SA  ("OST").   In  January,   1999,  the  Company  completed  the
acquisition  of  90% of OST  which  principally  processes  bovine  bone  tissue
products for orthopaedic and dental use.

Grafton(R) DBM segment  revenues  increased 1% to $9,905,000  from $9,802,000 in
third quarter of 1998 and increased 14% to $32,346,000  from  $28,349,000 in the
first nine months of 1998.  The  increase  resulted  from  increased  demand for
Grafton(R) DBM and a price increase  effective  January 1, 1999.  Grafton(R) DBM
segment revenues growth slowed in the third quarter of 1999 as compared with the
prior year same quarter  primarily  due to effects of  competition  and a summer
slowdown  in surgical  procedures.  We believe the slow down in growth will be a
short-term  issue as surgeons  try the  competitive  product and  determine  for
themselves the superiority of Grafton(R) DBM.

Base Tissue  segment  revenues  increased 71% to $6,525,000  from  $3,816,000 in
third quarter of 1998 and increased 60% to $20,043,000  from  $12,523,000 in the
first nine months of 1998. The increases are associated  with an increase in the
number of donors  processed  for our clients,  55% in the quarter and 43% in the
nine months,  and  revenues  from the  bio-d(TM)  threaded  cortical  bone dowel
launched at the end of 1998.

In the third quarter and first nine months of 1999, two of our Grafton(R)DBM and
Base Tissue segment clients accounted for 57% and 36% of consolidated  revenues,
respectively.

Gross Profit

Gross profit as a percentage of revenues was 68% in the third quarter and 69% in
the first nine months of 1999.  Gross profit as a percentage  of revenues in the
prior year was 71% in the third  quarter and 70% in the first nine  months.  The
decrease  results from; (i) the absorption of costs  associated  with additional
allograft  tissue  processing  capacity  which was added to meet the  continuing
growth in our allograft tissue business, and (ii) a decline in the percentage of
consolidated revenues coming from the Grafton(R) DBM Segment, which has a higher
gross profit margin than other services and products.

Marketing, General and Administrative

Marketing,  general and administrative  expenses increased  $2,105,000 or 43% in
the  third  quarter  and  $4,587,000  or 30% in the  first  nine  months of 1999
compared to the same periods in 1998.  The increase was  primarily  attributable
to: (i) incremental  agent  commissions  resulting from increased  volume in the
Grafton(R) DBM segment and (ii) expanded  marketing and  promotional  activities
associated with the roll out of two new products,  the bio-d(TM) system which is
included  in the  Base  Tissue  segment


                                       13
<PAGE>

and the Segmental Spinal Correction System(TM) ("SSCS"). Additionally, corporate
administrative  costs  increased  compared  to 1998  principally  as a result of
higher costs associated with patent  infringement  lawsuits and the inclusion of
OST's operating expenses.

Research and Development

Research and development expenses increased $231,000 or 21% in the third quarter
and  $963,000  or 29% in the  first  nine  months of 1999  compared  to the same
periods in 1998. The increase was primarily  attributable to increased  spending
in the Base Tissue segment associated with the continued  development of a viral
inactivation process and ongoing development of new allograft tissue products.

Operating Income

Operating income increased  $1,099,000 or 26% in the third quarter and increased
$4,458,000  or 39% in the first nine months of 1999 compared to the same periods
in 1998.  Grafton(R) DBM segment  operating income increased  $717,000 or 19% in
the third  quarter and  increased  $3,303,000 or 36% in the first nine months of
1999  compared to the same  periods in 1998.  Grafton(R)  DBM segment  operating
income in the quarter and nine months  includes  $1,750,000 of income  resulting
from the patent  litigation  settlement  (See Note 11 of "Notes to  Consolidated
Financial Statements").  In the quarter, the impact of the settlement was partly
offset by the absorption of costs  associated with additional  allograft  tissue
processing  capacity,  higher  costs  associated  with the  patent  lawsuit  and
relatively  flat revenue growth as compared with 1998.  The segment's  operating
income in the nine  months  was also  positively  impacted  by the  increase  in
revenues.  Base Tissue segment operating income increased  $1,055,000 or 127% in
the  third  quarter  and  $3,068,000  or 106% in the first  nine  months of 1999
compared to the same periods in 1998.  The  increases  result  principally  from
increases in revenue.  Other segment operating income decreased $673,000 or 204%
in the third  quarter  and  $1,913,000  or 233% in the first nine months of 1999
compared to the same periods in 1998.  The  decreases  result  principally  from
increased marketing expenses associated with the launch of the SSCS(TM) system.

Income Tax Provision

The effective income tax rate declined to approximately 41% in the third quarter
and 40% in the first  nine  months of 1999 from 42% and 41% in the same  periods
last year.

Liquidity and Capital Resources

At September 30, 1999, we had cash and  short-term  investments  of  $21,204,000
compared to  $18,041,000  at December  31, 1998.  We invest  excess cash in U.S.
Government-backed securities and investment grade commercial paper of major U.S.
corporations.  Working capital increased  $6,865,000 to $33,238,000 at September
30, 1999 compared to  $26,373,000  at December 31, 1998. The increase in working
capital  results   principally   from  an  increase  in  cash  and  investments,
inventories, deferred processing costs and the litigation settlement receivable,
net of a decrease in accounts receivable and an increase in accounts payable and
accrued  liabilities.  The increase in  inventories  of $1,979,000 is associated
with the  acquisition of the  Versalok(R)  System and the launch of the SSCS(TM)
system. The increase in deferred  processing costs is associated with the growth
in our Grafton(R) DBM and Base Tissue segments.

Net cash  provided by  operating  activities  was  $9,108,000  in the first nine
months of 1999, compared to cash provided by operating  activities of $9,390,000
in the first nine months of 1998. The decrease resulted primarily from increases
in inventories


                                       14
<PAGE>

and deferred  processing costs. Cash used in investing  activities  increased to
$16,946,000  in the first nine months of 1999 from  $6,518,000 in the first nine
months of 1998.  The  increase  results  principally  from;  (i) an  increase in
capital expenditures to $13,537,000 from $4,326,000 resulting from our continued
investment in facilities  and equipment  needed for current and future  business
requirements,  (ii) the purchase of an additional 85% interest in OST, and (iii)
the  acquisition of the  Versalok(R)  System.  In the fourth quarter of 1998, we
commenced  construction  of  a  new  allograft  tissue  processing  facility  in
Eatontown,  New Jersey. The estimated aggregate cost for the construction of the
building,   including   furniture,   fixtures  and  equipment  is  approximately
$32,000,000;  $21,500,000 of which will be funded through the building  mortgage
loan and equipment line of credit included in the credit facility concluded with
our bank in June,  1999.  The remaining  balance of  $10,500,000  will be funded
through  available cash reserves or anticipated cash flow from  operations.  Net
cash provided by financing  activities  increased to  $10,055,000  from net cash
used of  $396,000  in the first  nine  months  of 1998.  The  increase  resulted
principally  from  cash  proceeds  received  and  related  income  tax  benefits
associated with stock option  exercises and borrowings  under the revolving line
of credit.

In June,  1999, we replaced our domestic lines of credit with a credit  facility
that includes a $5,000,000  revolving line of credit, a $4,500,000 mortgage loan
and $17,000,000  equipment line of credit. At September 30, 1999, $3,000,000 was
outstanding  under the revolving  line of credit.  We also have a line of credit
with a Dutch bank,  which  provides  for  borrowings  of up to  5,000,000  Dutch
Guilders ("dfl"), or approximately $2,426,000 at the September 30, 1999 exchange
rate.  Analysis of our cash position and anticipated cash flow indicated that it
most likely would not be necessary to utilize a significant portion of this line
of credit and, therefore,  we agreed with the bank to limit borrowings,  if any,
to no more than dfl 3,000,000 or  approximately  $1,455,000 at the September 30,
1999 exchange rate.  Additionally,  we have a line of credit with a French bank,
which provides for borrowing of up to FRF 2,000,000,  or approximately  $360,000
at the  September  30, 1999  exchange  rate.  We believe  that our cash and cash
equivalents, short-term investments and available lines of credit, together with
anticipated  future cash flow from  operations,  will be  sufficient to meet our
near-term  requirements.  From time to time we may seek additional funds through
equity  or  debt  financing.  However,  there  can be no  assurances  that  such
additional  funds will be available,  or if  available,  that such funds will be
available on favorable terms.

Impact of Inflation and Foreign Currency Exchange Fluctuations

The results of our Company's operations for the periods discussed above have not
been significantly affected by inflation or foreign currency fluctuations.

Litigation

Osteotech,  Inc. is  involved in various  legal  proceedings  involving  product
liability and patent infringement  claims. For a discussion of these matters see
Notes 7 and 11 of "Notes to Condensed Consolidated  Financial Statements",  PART
II., ITEM 1. LEGAL  PROCEEDINGS  and our Annual Report on Form 10-K for the year
ended  December  31,  1998.  It is possible  that our results of  operations  or
liquidity  and capital  resources  could be  adversely  affected by the ultimate
outcome of the pending litigation or as a result of the costs of contesting such
lawsuits.


                                       15
<PAGE>

Year 2000

We recognize the need to ensure that Year 2000 issues will not adversely  impact
our  operations  and have  identified  our  potential  Year  2000  risk in three
categories:  internal  business  software and hardware;  internal  non-financial
systems; and noncompliance by suppliers and customers.

Internal Business Software and Hardware

Several years ago we determined that our existing business  information  systems
were not adequate to support the anticipated  growth in our business  operations
and purchased a fully integrated  management  information system,  which is Year
2000  compliant.  Most of the new  system  is  operational  at this time and the
remainder  of the system is scheduled to be  operational  in the fourth  quarter
1999.  The portion of the existing  system being  replaced has been modified and
tested for Year 2000 compliance and accordingly,  if the new system is not fully
operational by January 1, 2000, we do not expect disruption to our business. The
completion cost for  implementation of the remaining software is not expected to
be material.  All related hardware  supporting our internal business software is
currently Year 2000 compliant.

Internal Non-financial Systems

We have  completed  our  assessment  and testing of our  internal  non-financial
systems such as office equipment,  security systems and other business equipment
and determined that all critical systems are Year 2000 compliant.

Noncompliance by Suppliers and Customers

We  have  completed  our  assessment  of all of our  significant  suppliers  and
customers  to  determine  the extent to which we are  vulnerable  to those third
parties' failure to achieve Year 2000  compliance.  The majority of our critical
vendors have communicated  that they are Year 2000 compliant.  We are monitoring
the progress of those  vendors who are not  currently  Year 2000  compliant  but
expect to be compliant  before December 31, 1999 and have developed  contingency
plans  with  respect  to such  vendors to  prevent  disruption  to our  business
operations.  At this time we do not anticipate  incurring  additional  cost as a
result of such contingency plans.

Risk of Non-Compliance

Based on the progress we have made in  addressing  Year 2000  issues,  we do not
foresee  significant  risks associated with our year 2000 compliance  program at
this time.

ITEM 3.  QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK

Not Applicable


PART II.  OTHER INFORMATION

ITEM 1.  LEGAL PROCEEDINGS

Abercrombie v. AcroMed et al.

In  September,  1999,  plaintiffs  voluntarily  dismissed  the Company from this
action without prejudice.


                                       16
<PAGE>


GenSci Regeneration Laboratories, Inc. v. Osteotech, Inc.

In November,  1999,  the Company  settled all claims which it had filed  against
DePuy.  As part of the  settlement,  DePuy has agreed to stop selling the GenSci
products accused of infringing the Company's patents,  no later than February 4,
2001 and to pay the  Company  $3,000,000  as follows:  $2,000,000  in the fourth
quarter of 1999 and $250,000 at the end of each quarter in 2000. Payments in the
year 2000 will be made unless  DePuy  discontinues  selling the GenSci  products
during the year, at which time DePuy would not be obligated for payments  beyond
the quarter in which it stopped selling the GenSci products.

Medtronic  Sofamor Danek,  Inc.,  Sofamor Danek L.P. and Sofamor Danek Holdings,
Inc. v. Osteotech

In  September,  1999 the Company filed its answer and counter  claims  seeking a
declaratory  judgement  that the  patents in question in this action are invalid
and otherwise not infringed by the Company.  Plaintiffs filed their reply to the
counterclaims in October, 1999. The Company believes that the claims asserted in
this action are without  merit and intends to  vigorously  defend  against  such
claims.

Medtronic Sofamor Danek, Inc. v. Arthur Alfaro

In September, 1999, Medtronic Sofamor Danek, Inc. ("Medtronic"),  sued Arthur A.
Alfaro,  a former  Division  President of Medtronic  and currently the Company's
President and Chief  Operating  Officer,  in the Chancery Court of Tennessee for
the Thirtieth  Judicial  District at Memphis,  seeking to enjoin Mr. Alfaro from
divulging  alleged  confidential  information  or trade  secrets of Medtronic to
third  parties,  including  the Company,  and from working for the Company for a
period of twelve  months.  In  September,  1999,  the Court  issued a  temporary
restraining   order  prohibiting  Mr.  Alfaro  from  issuing  or  divulging  any
confidential  information  or trade secrets of Medtronic to any third party.  In
October,  1999,  Mr.  Alfaro  filed and served his  answer,  denying any and all
liability.  Pursuant  to an  employment  agreement  between  Mr.  Alfaro and the
Company,  the Company is paying Mr.  Alfaro's legal fees and costs for defending
this action.

ITEM 5. OTHER INFORMATION

On November 8, 1999, we announced  that Roger C.  Stikeleather,  Executive  Vice
President,  Sales &  Marketing,  left the  Company  effective  November 4, 1999.
Personnel who had been reporting to Mr.  Stikeleather now report directly to Mr.
Arthur A. Alfaro, Osteotech's President and Chief Operating Officer.

On November  10, 1999,  we  announced  that we settled all claims which had been
filed  against  DePuy in the patent  infringement  suit against  GenSci Labs and
GenSci Sciences and DePuy.  As part of the settlement,  DePuy has agreed to stop
selling  DynaGraft(TM)  Gel and Putty, the GenSci products accused of infringing
the  Company's  patents,  no later than  February 4, 2001 and to pay the Company
$3,000,000 as follows:  $2,000,000 in the fourth quarter of 1999 and $250,000 at
the end of each  quarter in 2000.  Payments in the year 2000 will be made unless
DePuy  discontinues  selling the GenSci  products during the year, at which time
DePuy would not be obligated for payments beyond the quarter in which it stopped
selling the GenSci products.



                                       17
<PAGE>

ITEM 6.  EXHIBITS AND REPORTS ON FORM 8-K

(a)  Exhibits (numbered in accordance with Item 601 of Regulation S-K)

         Exhibit                                                          Page
         Number       Description                                        Number
         ------       -----------                                        ------

         10.34        Employment Agreement with Arthur A. Alfaro
                      Dated September 13, 1999                             E-1

         10.35        Change in Control Agreement by and between
                      Osteotech and Arthur A. Alfaro                       E-12

         10.36        Settlement Agreement and General Release
                      Between DePuy AcroMed, Inc. and DePuy, Inc.
                      and Osteotech, Inc.                                  E-22

          27.0        Financial Data Schedule                              E-32

(b)  Reports on Form 8-K

     On September  13, 1999,  we filed with the  Commission a current  report on
     Form 8-K to  announce  that  Arthur A.  Alfaro  had  joined us in the newly
     created new position of President and Chief Operating  Officer.  Mr. Alfaro
     was also  elected to the  Company's  Board of  Directors.  He was  formerly
     President of the Thoracolumbar Division for Medtronic Sofamor Danek, Inc.

     On September  24, 1999,  we filed with the  Commission a current  report on
     Form 8-K to announce  that we did not expect third quarter 1999 revenue and
     earnings results to meet analysts' consensus estimates for the quarter.


                                       18
<PAGE>

                                   SIGNATURES


Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned thereunto duly authorized.




                                                         Osteotech, Inc
                                                  ------------------------------
                                                           (Registrant)





Date:    November 12, 1999                By:     /s/ Richard W. Bauer
                                                  ------------------------------
                                                  Richard W  Bauer
                                                  Chief Executive Officer




Date:    November 12, 1999                By:     /s/ Michael J. Jeffries
                                                  ------------------------------
                                                  Michael J  Jeffries
                                                  Executive Vice President
                                                  Chief Financial Officer



                                       19


                                                                   EXHIBIT 10.34

                              EMPLOYMENT AGREEMENT

     THIS  AGREEMENT  entered  into  the  13th  day of  September  1999  between
OSTEOTECH, INC., a Delaware corporation (the "Corporation") and Arthur A. Alfaro
(the "Employee").

                                   WITNESSETH:

     WHEREAS,  the  Corporation  desires to employ the Employee as its President
and Chief Operating Officer; and

     WHEREAS,  the Employee desires to accept such employment upon the terms and
conditions set forth herein.

     NOW,  THEREFORE,  in  consideration of the mutual covenants and obligations
hereinafter set forth, the parties hereto agree as follows:

     1.  Employment.  The  Corporation  hereby  employs  the  Employee,  and the
Employee  hereby  accepts  employment by the  Corporation as President and Chief
Operating  Officer of the  Corporation  upon the terms and  conditions set forth
herein.

     2. Term.  Unless sooner  terminated in accordance with this Agreement,  the
term of this  Agreement and the term of employment of the Employee  shall be for
two (2) years commencing on the Effective Date hereof and shall be automatically
renewable for successive additional two (2) year terms unless at least three (3)
months prior to the expiration of the initial  two-year period or any subsequent
two-year term the Corporation terminates this Agreement by written notice to the
Employee,  whereupon  this  Agreement  shall  be  terminated  at the  end of the
applicable  two-year  period  (with such  initial two year term and any two year
renewal  thereof,  unless sooner  terminated in accordance  with this  Agreement
being the "Term of Employment").


                                      E-1
<PAGE>

     3. Duties. The Employee shall perform such duties and services and shall be
allocated such resources,  consistent  with his position,  as may be assigned to
him from time to time by the Chief Executive  Officer and the Board of Directors
of the Corporation.  In furtherance of the foregoing, the Employee hereby agrees
to perform well and faithfully such duties and responsibilities.

     4. Time to be Devoted to Employment.

     4(a). The Employee shall devote his full time and energy to the business of
the  Corporation  except for vacations,  holidays and personal days and absences
due to temporary  illness,  during the Term of Employment and except as approved
by the Board of Directors.

     4(b).  During the Term of Employment,  the Employee shall not be engaged in
any other business  activity.  Employee hereby represents that he is not a party
to any agreement  which would be an  impediment to entering into this  Agreement
and  that  he is  permitted  to  enter  into  this  Agreement  and  perform  the
obligations hereunder.

     5. Compensation; Reimbursement.

     5.1(a)  During  the  Term  of  Employment,   the  Corporation  (or  at  the
Corporation's  option,  any  subsidiary or affiliate  thereof)  shall pay to the
Employee  an annual  base salary  ("Base  Salary")  of Two Hundred  Seventy-Five
Thousand Dollars ($275,000) payable in bi-monthly installments.  The Base Salary
shall be reviewed  annually  and be subject to increase at the option and in the
sole discretion of the Board of Directors of the Corporation.

     5.1(b) During the Term of Employment,  on an annual basis,  Employee may be
entitled  to a bonus  and stock  option  grants  as  determined  by the Board of
Directors of the Corporation based on Employee's  performance.  In calendar year
1999,  the employee shall receive a Twenty  Thousand  Dollar  ($20,000)  signing
bonus and a performance  bonus of Fifty Thousand Dollars  ($50,000)


                                      E-2
<PAGE>

100% payable in December 1999.  Thereafter,  there will be no further guaranteed
or minimum bonus and the award,  if any,  will be within the sole  discretion of
the Board of Directors.

     5.1(c).  During the Term of  Employment,  the Employee shall be entitled to
family medical and dental  insurance  coverage,  short and long term  disability
coverage,  eligibility for participation in the  Corporation's  401K plan and to
such other fringe  benefits such as life  insurance as are made  available  from
time to time to the  executives  of the  Corporation,  including  four (4) weeks
vacation per calendar year.

     5.1(d).  The Corporation shall reimburse  Employee,  in accordance with its
practice  from  time to time for other  employees  of the  Corporation,  for all
reasonable and necessary travel expenses, disbursements and other reasonable and
necessary  incidental  expenses  incurred  by  him  for  or  on  behalf  of  the
Corporation in the performance of his duties hereunder upon  presentation by the
Employee to the Corporation of appropriate vouchers.

     5.1(e).  The  Corporation  shall  reimburse  Employee for other  reasonable
expenses during the Term of Employment as follows:

          (i) Reasonable  travel and lodging expenses to locate suitable housing
     accommodations in the State of New Jersey.

          (ii) Reasonable expenses for packing,  shipping, storage and unpacking
     of personal household goods in connection with Employee's relocation to New
     Jersey.

          (iii) Twice a month weekend travel for Employee between New Jersey and
     Memphis during the  relocation  period.  Normal and customary  expenses for
     house  hunting  trips for his  family to find and  purchase  a house in New
     Jersey.

          (iv)  Allowance  for  incidental  moving  expenses  of  Five  Thousand
     ($5,000) dollars.



                                      E-3
<PAGE>

     5.1(f).  The  Corporation  shall provide  Employee  with suitable  housing,
within  reasonable  commuting  distance  of  the  Corporation's  offices,  until
permanent housing  accommodations are acquired and inhabited or for up to twelve
(12) months, whichever period is shorter.

     5.1(g).  In the event that legal  action is brought  against  Employee  for
breach of the non-compete  provisions of the Employment Agreement by and between
Medtronic Sofamor Danek, Inc. and Employee,  the Corporation  (Osteotech) agrees
to pay the  reasonable  legal fees and  incidental  expenses for defending  such
legal action.  In the event that any verdict or  settlement  is awarded  against
Employee for any breach,  the  Corporation  agrees to pay that portion for which
the Employee is liable.

     5.2  Corporation  agrees to grant to Employee  effective  October 1, 1999 a
stock  option  agreement to purchase two hundred  thousand  (200,000)  shares of
common stock with the per share price based on the closing price of the stock on
October 1,  1999.  One-fourth  (1/4) of the option  shall vest one year from the
effective date and one-fourth (1/4) shall vest thereafter on each anniversary of
the  effective  date of this  Agreement so long as the  Employee  remains in the
employ of the Corporation on that date. The option shall  terminate  ninety (90)
days after  termination of the Employee's  employment  with the  Corporation and
shall be granted in accordance  with the  Corporation's  Incentive  Stock Option
Plan as amended from time to time.

     6.  Involuntary  Termination.  If the  Employee  dies  during  the  Term of
Employment,  his employment hereunder and the Term of Employment shall be deemed
to cease as of the date of his death.

     7.  Termination For Cause.  The Corporation may terminate the employment of
the Employee hereunder and the Term of Employment at any time during the Term of
Employment for "cause" (such termination being hereinafter called a "Termination
For Cause") by giving the Employee notice


                                      E-4
<PAGE>

of such termination, upon the giving of which such termination shall take effect
immediately.  For the  purposes of this  Section 7,  "cause"  shall mean (i) the
Employee's  willful  misconduct  with respect to the business and affairs of the
Corporation or any subsidiary or affiliate thereof,  which action materially and
adversely  affects the business or affairs of the  Corporation or any subsidiary
or affiliate thereof, (ii) the Employee fails in any material respect to observe
and perform his  obligations and duties  hereunder,  (iii) the commission by the
Employee of an act involving  embezzlement  or fraud against the  Corporation or
commission or conviction of a felony,  or (iv) failure to abide in some material
respect by the Corporation's rules of conduct, terms and conditions set forth in
the Corporation's handbook, as amended from time to time.

     8. Termination  Without Cause. The Corporation may terminate the employment
of the Employee hereunder and the Term of Employment at any time without "cause"
upon thirty (30) days prior written notice (such  termination  being hereinafter
called a "Termination  Without Cause").  Upon a Termination without Cause during
the Term of  Employment,  Employee  shall be entitled to receive his Base Salary
for twelve  (12)  months  from date of  termination  and his Base  Salary for an
additional  twelve  (12)  months or in the latter  case until  Employee  obtains
comparable  employment,  whichever  occurs  sooner,  plus all bonus payouts made
prior to the time of termination.  In addition, upon a Termination Without Cause
at any time, the Corporation shall continue to pay the Employee's family medical
insurance  premiums  under the  Corporation's  medical  insurance plan and other
benefits  (including  outplacement  benefits as long as you are actively seeking
employment)  provided in Section 5.1(c) for  twenty-four  (24) months  following
such  termination or until Employee  obtains  comparable  employment,  whichever
occurs sooner.


                                      E-5
<PAGE>

     9. Voluntary Termination. Any termination of the employment of the Employee
hereunder  otherwise  then  as  a  result  of  an  Involuntary  Termination,   a
Termination  For Cause or a  Termination  Without  Cause shall be deemed to be a
"Voluntary Termination". A Voluntary Termination shall be deemed to be effective
immediately upon such termination.

     10. Effect of Termination of Employment.

     10(a). Upon the termination of the Employee's employment hereunder pursuant
to a Voluntary Termination,  Involuntary Termination or a Termination For Cause,
neither the Employee nor his beneficiary or estate shall have any further rights
or claims against the Corporation under this Agreement except to receive:

          (i) The unpaid  portion  of the Base  Salary  provided  for in Section
     5.1(a), computed on a pro rata basis to the date of termination;

          (ii)  Reimbursement  for any expenses for which the Employee shall not
     have theretofore been reimbursed as provided in Section 5.1(d);

          (iii) Payment of all accrued and unused vacation time.

     10(b). Upon the termination of the Employee's employment hereunder pursuant
to a Termination  Without  Cause,  neither the Employee nor his  beneficiary  or
estate shall have any further  rights or claims  against the  Corporation  under
this  Agreement  except to receive a termination  payment equal to that provided
for in Section 10(a) hereof, plus the amounts set forth in Section 8, if any.

     11. General Provisions

     11(a).  This  Agreement  and any or all terms  hereof  may not be  changed,
waived,  discharged,  or terminated  orally, but only by way of an instrument in
writing signed by the parties.



                                      E-6
<PAGE>

     11(b). This Agreement shall be governed by and construed in accordance with
the laws of the State of New Jersey,  without reference to the conflicts of laws
of the State of New Jersey or any other jurisdiction.

     11(c).  If any  portion of this  Agreement  shall be found to be invalid or
contrary  to public  policy,  the same may be modified or stricken by a Court of
competent  jurisdiction,  to the extent  necessary to allow the Court to enforce
such  provision in a manner which is as consistent  with the original  intent of
the  provision as possible.  The  striking or  modification  by the Court of any
provision shall not have the effect of invalidating the Agreement as a whole.

     11(d).  The  obligations of Sections 8, 10, 11, 12, 13 and 14 shall survive
termination of this Agreement.

     12.  Corporation  Rights  to  Intellectual  Property.  The  Employee  shall
promptly  disclose,  grant and assign  ownership to the Corporation for its sole
use and benefit any and all inventions,  improvements,  information,  copyrights
and  suggestions  (whether  patentable or not),  which he may develop,  acquire,
conceive or reduce to practice while employed by the Corporation (whether or not
during usual  working  hours),  together with all patent  applications,  letters
patent,  copyrights and reissues  thereof that may at any time be granted for or
upon any such invention, improvement or information. In connection therewith:

          (i) The  Employee  shall  without  charge,  but at the  expense of the
     Corporation,  promptly at all times  hereafter  execute  and  deliver  such
     applications,  assignments,  descriptions  and other  instruments as may be
     reasonably  necessary or proper in the opinion of the  Corporation  to vest
     title to any such inventions,  improvements,  technical information, patent
     applications,  patents,  copyrights or reissues  thereof in the Corporation
     and


                                      E-7
<PAGE>

     to enable it to obtain  and  maintain  the entire  right and title  thereto
     throughout the world; and

          (ii) The  Employee  shall  render to the  Corporation  at its  expense
     (including  reimbursement  to  the  Employee  of  reasonable  out-of-pocket
     expenses  incurred  by  the  Employee  and a  reasonable  payment  for  the
     Employee's  time  involved  in case he is not then in its  employ) all such
     assistance as it may reasonably  require in the prosecution of applications
     for said patents,  copyrights or reissues  thereof,  in the  prosecution or
     defense  of  interferences   which  may  be  declared  involving  any  said
     applications,  patents or  copyrights  and in any  litigation  in which the
     Corporation  may be  involved  relating  to any such  patents,  inventions,
     improvements or technical information.

     13. Protection of Information.

     13(a). Employee hereby covenants with Corporation that, throughout the term
of his  employment  by  Corporation,  Employee  will  serve  Corporation's  best
interests  loyally  and  diligently.  Throughout  the  course of  employment  by
Corporation and thereafter, Employee will not disclose or provide to any person,
firm,  corporation  or  entity  (except  when  authorized  by  Corporation)  any
information,  materials, biologics or animals which are owned by the Corporation
or which come into the possession of the Corporation from a third party under an
obligation  of  confidentiality,   including  without  limitation,   information
relating to trade secrets, business methods,  products,  processes,  procedures,
development or experimental projects,  suppliers, customer lists or the needs of
customers or prospective customers,  clients, etc.  (collectively  "Confidential
Information"),  which  Confidential  Information,  comes into his  possession or
knowledge during the Term of Employment,  and he will not use such  Confidential
Information  for his  own  purpose  or for  the


                                      E-8
<PAGE>

purpose of any person, firm, corporation or entity, other than the Corporation.

     13(b).  The  provisions  of Section  13(a) shall not apply to the following
Confidential Information:

          (i)  Confidential  Information  which  at the  time of  disclosure  is
     already in the public domain;

          (ii)  Confidential  Information which the Employee can demonstrate was
     in his  possession  or known  to him  prior  to the  effective  date of his
     employment by the Corporation;

          (iii) Confidential  Information which subsequently becomes part of the
     public domain through no fault of the Employee;

          (iv)  Confidential  Information  which  becomes  known to the Employee
     through a third party who is under no obligation of  confidentiality to the
     Corporation; and

          (v) Confidential  Information which is required to be disclosed by law
     or by judicial or administrative proceedings.

     14. Non-Compete. Employee agrees that during the Term of Employment and for
the period of time  Employee is paid salary and  benefits as outlined in Section
8, he shall not  directly  or  indirectly  be  engaged  in or  assist  others in
engaging  in any  business or  activity  which is involved in selling  products,
processes or services  which compete with any  significant  product,  process or
service which  Corporation  is  developing,  marketing or selling at the time of
such  termination  whether  his  involvement  shall be as an owner  (except  for
passive  ownership of up to five percent (5%) of the  securities  of a company),
officer, director, employee,  consultant, partner or agent. For purposes of this
provision,  products,  processes or services  which  Corporation is marketing or
selling shall be deemed  "significant"  if sales


                                      E-9
<PAGE>

of such  products,  processes  or  services  exceed  ten  percent  (10%)  of the
Corporation's total sales.

     15. Notices. Notices and other communications hereunder shall be in writing
and  shall  be  delivered  personally  or sent by air  courier  or  first  class
certified or registered  mail,  return  receipt  requested and postage  prepaid,
addressed as follows unless the party specifies a new address in writing:

              If to the Employee:          Arthur A. Alfaro
                                           10201 Shrewsbury Run West
                                           Collierville, TN 38017

              If to the Corporation:       Osteotech, Inc.
                                           51 James Way
                                           Eatontown, NJ 07724

All notices and other  communications  given to any party  hereto in  accordance
with the provisions of this Agreement  shall be deemed to have been given to the
date of delivery if  personally  delivered;  on the  business day after the date
when sent if sent by air courier;  and on the third  business day after the date
when sent if sent by mail,  in each case  addressed to such party as provided in
this Section or in  accordance  with the latest  unrevoked  direction  from such
party.

     16.  Headings.  The section  headings  contained in this  Agreement are for
reference  purposes  only  and  shall  not  affect  in any  way the  meaning  or
interpretation of this Agreement.

     17.  Assignment.  This  Agreement is personal in its nature and the parties
hereto  shall not,  without  the consent of the other,  assign or transfer  this
Agreement or any rights or obligations  hereunder;  provided,  however, that the
provisions  hereof  shall  inure to the  benefit  of, and be  binding  upon each
successor of the Corporation, whether by merger, consolidation,  transfer of all
or   substantially   all  assets,   or   otherwise   and  the  heirs  and  legal
representatives of the employee.

                                      E-10
<PAGE>

     IN WITNESS WHEREOF, the parties have duly executed this Agreement as of the
date first above written.

                                  Corporation:   OSTEOTECH, INC.


                                                 /s/ Richard W. Bauer
                                                 -------------------------------
                                                 By:      Richard W. Bauer
                                                 Title:  Chief Executive Officer


                                  Employee:      /s/ Arthur A. Alfaro
                                                 -------------------------------
                                                 Arthur A. Alfaro




                                      E-11

                                                                   EXHIBIT 10.35

                           CHANGE IN CONTROL AGREEMENT

     AGREEMENT  by and between  Osteotech,  Inc.,  a Delaware  corporation  (the
"Company"), and Arthur A. Alfaro (the "Executive"),  dated as of the 13th day of
September, 1999.

     The Board of Directors of the Company (the "Board") has determined  that it
is in the best interests of the Company and its  stockholders to assure that the
Company will have the continued dedication of the Executive, notwithstanding the
possibility,  threat or occurrence of a Change in Control (as defined in Section
1(e)) of the  Company.  The Board  believes it is  imperative  to  diminish  the
distraction of the Executive by virtue of the personal  uncertainties  and risks
created  by a pending  or  threatened  Change in Control  and to  encourage  the
Executive's  full attention and  dedication to the Company  currently and in the
event of any  threatened  or  pending  Change in  Control,  and to  provide  the
Executive with  compensation and benefits  arrangements upon a Change in Control
which ensure that the  compensation  and benefits  expectations of the Executive
will be satisfied and that such  compensation  and benefits are competitive with
those of other corporations. Therefore, in order to accomplish these objectives,
the Board has caused the Company to enter into this Agreement.

     NOW, THEREFORE, IT IS HEREBY AGREED AS FOLLOWS:

     1. Certain Definitions.

     For purposes of this Agreement:

     (a) An "Affiliate"  means any member of the same  affiliated  group (within
the meaning of Section  1504 of the Internal  Revenue  Code of 1986,  as amended
(the "Code"),  determined  without regard to Section 1504(b) of the Code),  that
includes the Company.

     (b) The Executive's  "Base Period  Compensation"  is (i) the average annual
"compensation"  (as defined  below) which was includible in his gross income for
his base period (i.e.,  his most recent five taxable years or such lesser number
of taxable  years or  portions  thereof  during  which the  Executive  performed
services for the Company  ending before the date of the Change in Control);  and
(ii) if Executive's  base period  includes a short taxable year or less than all
of a taxable year,  compensation for such short or incomplete taxable year shall
be annualized for the base period. (In annualizing  compensation,  the frequency
with which payments are expected to be made over an annual period shall be taken
into account.  Thus, any amount of  compensation  for such a short or incomplete
taxable year that represents a payment that would not be made more than once per
year shall not be  annualized).  For  purposes of this  definition,  Executive's
"compensation" is the compensation which was payable to him by the Company or an
Affiliate,  determined without regard to the following Sections of the Code: 125
(cafeteria  plans),  402(a)(8)  (cash or  deferred  arrangements),  402(h)(1)(B)
(elective  contributions to simplified employee  pensions),  and, in the case of
employer  contributions  made pursuant to a salary reduction  agreement,  403(b)
(tax sheltered annuities).



                                      E-12
<PAGE>

     (c) The "Commencement  Date" shall mean the first date during the Change in
Control Period (as defined in Section 1(d)) that a Change in Control (as defined
in Section 1(e)) occurs.

     (d) The "Change in Control Period" shall mean the period  commencing on the
date hereof and ending on the third  anniversary  of the date hereof;  provided,
however,  that  commencing on the first  anniversary of the date hereof,  and on
each successive annual anniversary of the date hereof (such date and each annual
anniversary thereof shall be hereinafter referred to as the "Renewal Date"), the
Change in Control  Period  shall be  automatically  extended so as to  terminate
three years from such Renewal Date, unless at least sixty (60) days prior to the
Renewal Date the Company shall give notice to the  Executive  that the Change in
Control Period shall not be so extended.

     (e) "Change in Control" shall mean:

          (i) A "Board Change" which, for purposes of this Agreement, shall have
     occurred  if a majority  of the seats (not  counting  vacant  seats) on the
     Company's  Board were to be occupied by  individuals  who were  neither (A)
     nominated by a majority of the  Incumbent  Directors  nor (B)  appointed by
     directors so nominated.  An  "Incumbent  Director" is a member of the Board
     who has been either (A)  nominated  by a majority of the  directors  of the
     Company then in office or (B)  appointed by  directors  so  nominated,  but
     excluding,  for this purpose,  any such individual whose initial assumption
     of office  occurs as a result  of either an actual or  threatened  election
     contest (as such term is used in Rule 14a-11 of Regulation 14A  promulgated
     under the Securities Exchange Act of 1934, as amended (the "Exchange Act"))
     or other actual or threatened  solicitation of proxies or consents by or on
     behalf of a Person other than the Board; or

          (ii) The  acquisition by any  individual,  entity or group (within the
     meaning of Section  13(d)(3) or 14(d)(2) of the Exchange  Act) (a "Person")
     of beneficial ownership (within the meaning of Rule 13d-3 promulgated under
     the Exchange Act) of a majority of the then outstanding  voting  securities
     of the Company (the  "Outstanding  Company Voting  Securities");  provided,
     however,  that the following  acquisitions shall not constitute a Change in
     Control:  (A) any acquisition by the Company, or (B) any acquisition by any
     employee  benefit plan (or related  trust)  sponsored or  maintained by the
     Company or any  corporation  controlled  by the Company,  or (C) any public
     offering,  private placement or other issuance by the Company of its voting
     securities; or

          (iii) A merger or  consolidation of the Company with another entity in
     which  neither the Company nor a corporation  that,  prior to the merger or
     consolidation,  was a  subsidiary  of the Company,  shall be the  surviving
     entity; or

          (iv) A merger or consolidation of the Company  following which (A) the
     Company or a corporation that, prior to the merger or consolidation,  was a
     subsidiary of the Company shall be the surviving  entity and (B) a majority
     of the  Outstanding  Company  Voting  Securities  is owned  by a Person  or
     Persons  who were not  beneficial  owners  (within  the  meaning of Section
     13(d)(3) or 14(d)(2) of the Exchange Act) of a majority of the  Outstanding
     Company   Voting   Securities   immediately   prior  to  such   merger   or
     consolidation; or



                                      E-13
<PAGE>

          (v) A voluntary or involuntary liquidation of the Company; or

          (vi) A sale or  disposition  by the  Company  of at  least  80% of its
     assets in a single  transaction or a series of  transactions  (other than a
     sale  or  disposition  of  assets  to a  subsidiary  of  the  Company  in a
     transaction  not  involving  a Change in  Control or a change in control of
     such subsidiary).

     2. Employment Period.

     (a) Term of Employment.  Commencing on the Commencement  Date and ending on
the first  anniversary  of such date (the  "Employment  Period"),  the Executive
hereby  agrees to remain in the employ of the  Company,  and the Company  hereby
agrees to continue the Executive in its employ,  in accordance with, and subject
to, the terms and provisions of this Agreement, in the capacity of President and
Chief  Operating  Officer   responsible  for,  among  other  things,   directing
Operations,  Sales, Marketing, Research and Development functions of the Company
and, subject to the general supervision of the Chief Executive Officer, and such
other duties and responsibilities as are not inconsistent with the express terms
of this Agreement.

     (b) Position and Duties.

          (i)  During  the  Employment  Period,  (A)  the  Executive's  position
     (including status, offices, titles and reporting requirements),  authority,
     duties and responsibilities shall be in accordance with Section 2(a) hereof
     and (B) the  Executive's  services shall be performed at the location where
     the Executive was employed  immediately  preceding the Commencement Date or
     any  office  which is the  headquarters  of the  Company  and is less  than
     fifteen (15) miles from such location.

          (ii)  During the  Employment  Period,  and  excluding  any  periods of
     vacation and sick leave to which the  Executive is entitled,  the Executive
     agrees to devote reasonable attention and time during normal business hours
     to the business and affairs of the Company and, to the extent  necessary to
     discharge the responsibilities  assigned to the Executive hereunder, to use
     the  Executive's   reasonable  best  efforts  to  perform   faithfully  and
     efficiently such  responsibilities.  During the Employment  Period it shall
     not be a violation  of this  Agreement  for the  Executive  to (A) serve on
     corporate,  civic or charitable boards or committees, (B) deliver lectures,
     fulfill speaking engagements or teach at educational institutions,  and (C)
     manage  personal  investments,  so long as such activities do not interfere
     with the performance of the Executive's  responsibilities as an employee of
     the Company in accordance with this Agreement.

     (c) Compensation.

          (i) Base Salary.  During the Employment  Period,  the Executive  shall
     receive an annual base salary  ("Annual Base Salary") in an amount at least
     equal to that  which he was  receiving  immediately  prior to the Change in
     Control.

          (ii) Incentive,  Savings Retirement and Stock Option Plans. During the
     Employment  Period,  the Executive  shall be entitled to participate in all
     incentive,  savings, retirement and stock option plans, practices, policies
     and programs applicable  generally to other peer executives of the


                                      E-14
<PAGE>

     Company, but in no event shall such plans, practices, policies and programs
     provide the Executive with  opportunities  and benefits less favorable than
     those in effect and applicable to the Executive  immediately  preceding the
     Change in Control.

          (iii)  Benefit  Plans.  During the  Employment  Period,  the Executive
     and/or the  Executive's  family,  as the case may be, shall be eligible for
     participation  in and shall  receive all  benefits  under  welfare  benefit
     plans, practices, policies and programs provided by the Company (including,
     without  limitation,  medical,  prescription,  dental,  disability,  salary
     continuance,  employee  life,  group  life,  accidental  death  and  travel
     accident  insurance plans and programs) to the extent applicable  generally
     to other peer executives of the Company,  but in no event shall such plans,
     practices,  policies and programs provide the Executive with benefits which
     are less  favorable  than such plans,  practices,  policies and programs in
     effect and applicable to the Executive  immediately preceding the Change in
     Control.

          (iv) Expenses.  During the Employment  Period,  the Executive shall be
     entitled to receive  prompt  reimbursement  for all  reasonable  employment
     related expenses incurred by the Executive in accordance with the policies,
     practices and  procedures of the Company which shall not be less  favorable
     than those in effect immediately preceding the Change in Control.

          (v) Office  and  Support  Staff.  During the  Employment  Period,  the
     Executive  shall be  entitled  to an office or  offices  of a size and with
     furnishings,  and to exclusive  personal  secretarial and other assistance,
     which shall be at least  equal to that  provided  to the  Executive  by the
     Company immediately preceding the Change in Control.

          (vi)  Vacation.  During  the  Employment  Period  Executive  shall  be
     entitled to paid  vacations  at least equal to that to which the  Executive
     was entitled immediately preceding the Change in Control.

          (vii) Options. Upon a Change in Control all options to purchase shares
     of the Company's Common Stock held by Executive (the "Options"), whether or
     not vested,  shall vest and become  exercisable  in  accordance  with their
     terms  immediately  prior to the  effective  date of such Change in Control
     (and Executive  will be provided a reasonable  opportunity to exercise such
     Options  prior to such  effective  date),  notwithstanding  anything to the
     contrary  contained  in the option  certificates  or any plan  covering the
     Options  collectively,  the ("Plan").  Upon a Change in Control all Options
     held by Executive  shall be exercisable in accordance  with their terms for
     such securities or property to which Executive would have been entitled had
     Executive   exercised  such  Options  prior  to  such  Change  in  Control,
     notwithstanding  anything to the contrary  contained  in any Plan  covering
     such  Options.  Upon a Change in Control  pursuant to Section  1(e)(iii) or
     1(e)(v),  all  Options  held by  Executive,  whether or not  vested,  shall
     terminate as of the effective  date of such Change in Control to the extent
     not previously exercised,  provided that Executive shall have been provided
     with a  reasonable  opportunity  to  exercise  such  options  prior to such
     effective date,  notwithstanding  anything to the contrary contained in the
     Plan covering such Options.


                                      E-15
<PAGE>

     3. Termination of Employment.

     (a)  Death  or  Disability.  The  Executive's  employment  shall  terminate
automatically  upon the Executive's  death during the Employment  Period. If the
Company  determines  in good  faith that the  Disability  of the  Executive  has
occurred during the Employment  Period (pursuant to the definition of Disability
set forth below), it may give to the Executive written notice in accordance with
Section 3(d) of its intention to terminate the Executive's  employment.  In such
event, the Executive's  employment with the Company shall terminate effective on
the 30th day after  receipt of such  notice by the  Executive  (the  "Disability
Effective Date"), provided that, within the thirty (30) days after such receipt,
the  Executive  shall  not  have  returned  to  full-time   performance  of  the
Executive's  duties.  For purposes of this Agreement,  "Disability" shall mean a
physical or mental  condition  which  prohibits  Executive  from  performing his
duties hereunder for a continuous six (6) month period or for a total of six (6)
months during any eighteen (18) month period.

     (b) Just Cause. Executive's employment may be terminated by the Company for
Just Cause. For purposes hereof, "Just Cause" shall mean:

          (i) The  commission by Executive of a willful act of material fraud in
     the performance of his duties on behalf of the Company; or

          (ii) The  conviction  of  Executive  for  commission  of a  felony  in
     connection with the performance of his duties on behalf of the Company.

     Prior to  termination  for Just Cause,  the Board shall by a majority  vote
have  declared  that  Executive's  termination  is for Just  Cause  specifically
stating the basis for such determination.

     (c) Good Reason. Executive's employment during the Employment Period may be
terminated by Executive  with Good Reason.  For purposes  hereof,  "Good Reason"
shall mean:

          (i) The  assignment  to  Executive  of any  duties of  lesser  status,
     dignity and character  than his duties  immediately  prior to the Change in
     Control  or a  substantial  reduction  in  the  nature  or  status  of  his
     responsibilities  from those in effect  immediately  prior to the Change in
     Control;

          (ii) Any  failure by the  Company  to comply  with the  provisions  of
     Section 2(c);

          (iii)  Relocation of  Executive's  office to a location  which is more
     than fifteen (15) miles from the  location in which  Executive  principally
     worked for the Company  immediately prior to the Change in Control;  or his
     being required by the Company in order to perform  duties of  substantially
     equal   status,   dignity  and  character  to  those  duties  he  performed
     immediately  prior to the  Change in  Control  to  travel on the  Company's
     business to a  substantially  greater  extent than is  consistent  with his
     business travel obligations immediately prior to a Change in Control;

          (iv) The failure by the Company to comply with Section 6(a),  provided
     that the  successor  has received at least twenty (20) days' prior  written
     notice from the Company or the  Executive  of the  requirements  of Section
     6(a); or,



                                      E-16
<PAGE>

          (v) The voluntary  termination  by the Executive for any reason at any
     time after the 180th day immediately following a Change in Control.

     For purposes of this  Sections 3(c) any good faith  determination  of "Good
Reason"  made by the  Executive  shall  in all  cases be  conclusive;  provided,
however, that for purposes of Sections 3(c)(i),  (ii), (iii) and (iv), Executive
shall have given the  Company  prior  written  notice  thereof and not less than
twenty (20) days to cure such "Good Reason".

     (d) Notice of Termination. Any termination by the Company for Just Cause or
by the Executive for Good Reason shall be  communicated by Notice of Termination
to the other party  hereby given in  accordance  with Section 7. For purposes of
this  Agreement,  a "Notice of  Termination"  means a written  notice  which (i)
indicates the specific termination provision in this Agreement relied upon, (ii)
to the  extent  applicable,  sets  forth in  reasonable  detail  the  facts  and
circumstances  claimed to  provide a basis for  termination  of the  Executive's
employment  under the  provision so indicated  and (iii)  specifies  the Date of
Termination  (as defined  below)  (which date shall be not more than thirty (30)
days after the giving of such  notice).  The  failure  by the  Executive  or the
Company to set forth in the Notice of Termination any fact or circumstance which
contributes  to a showing of Good Reason or Just Cause shall not waive any right
of the  Executive  or the Company  hereunder  or preclude  the  Executive or the
Company from asserting such fact or circumstance in enforcing the Executive's or
the Company's rights hereunder.

     (e) Date of Termination.  "Date of Termination"  means the date the Company
or the  Executive  specifies  as the  date  of  termination  in  the  Notice  of
Termination or if the Executive's employment is terminated by reason of death or
Disability,  the Date of Termination shall be the date of death of the Executive
or the Disability Effective Date, as the case may be.

     4. Obligations of Company upon Termination.

     (a)  Termination  by Company for Just Cause.  If at any time on or prior to
the 180th day following the Commencement Date, the Executive's  employment shall
be terminated by the Company for Just Cause,  then,  Executive shall receive all
then  accrued  pay,  benefits,   executive  compensation  and  fringe  benefits,
including  (but not limited  to),  pro rata bonus and  incentive  plan  earnings
through the Date of Termination,  plus the amount of any compensation previously
deferred by the Executive,  in each case to the extent  theretofore  unpaid. The
foregoing  payments and benefits  shall be deemed  compensation  payable for the
duties to be performed by Executive  pursuant to Section 2. If at any time after
the 180th day following the Commencement Date, the Executive's  employment shall
be  terminated  by the  Company  for Just  Cause,  then the  Executive  shall be
entitled to the payment and benefits described in Section 4(b), below.

     (b) Termination by Executive for Good Reason; Termination by the Company at
Any Time Other Than For Just  Cause;  Termination  by the Company For Just Cause
After the 180th Day Following the Commencement Date; Termination Upon Expiration
of the Employment  Period.  If (i) the Company shall  terminate the  Executive's
employment  at any time other than for Just Cause;  or,  (ii) the Company  shall
terminate  Executive's  employment  for Just Cause after the 180th day following
the Commencement Date; or, (iii) the Executive shall terminate his employment at
any time for Good Reason;  or (iv) the  Executive's  employment


                                      E-17
<PAGE>

with the Company shall  terminate upon the expiration of the Employment  Period,
in addition to any other sums, benefits or compensation otherwise payable to him
by the Company:

          (i)  Executive  shall  receive,  no later  than  the  next pay  period
     following  the  Date  of  Termination,  all  then  accrued  pay,  benefits,
     executive compensation and fringe benefits, including (but not limited to),
     his pro rata bonus and incentive plan earnings  accrued through the Date of
     Termination, plus the amount of any compensation previously deferred by the
     Executive, in each case to the extent theretofore unpaid;

          (ii)  Executive  shall  receive,  at the Company's  expense,  medical,
     health  and  disability  benefits  which are  substantially  similar to the
     benefits the Company is providing him  immediately  preceding the Change in
     Control for a period of thirty-six  (36) months  immediately  following the
     Date of Termination;

          (iii)  Executive shall receive an amount equal to one dollar less than
     the sum of (A)  300% of his Base  Period  Compensation,  plus (B)  interest
     thereon for the period beginning on the Commencement  Date through the date
     or dates of  payment,  at a rate  equal to 120% of the  applicable  Federal
     rate,   determined   under   Section   1274(d)  of  the  Code,   compounded
     semiannually.

          (iv) Except in the case of a termination by the Company for Just Cause
     or a voluntary  termination  by the  Executive in  accordance  with Section
     3(c)(v),  Executive  shall  receive  the  balance  of  all  pay,  benefits,
     compensation and fringe benefits,  including (but not limited to), pro rata
     salary,  bonus and incentive plan earnings payable through the remainder of
     the Employment Period; and,

          (v) Except in the case of a termination  by the Company for Just Cause
     or a voluntary  termination  by the  Executive in  accordance  with Section
     3(c)(v),  Executive shall be entitled to a private office with  furnishings
     and secretarial and other reasonable services for the period beginning with
     the Date of Termination and ending on the first anniversary thereof.

     The foregoing  payments and benefits shall be deemed  compensation  payable
for duties to be performed  by  Executive  pursuant to Section 2. Except for the
payments and benefits described in Sections 4(b)(i),  4(b)(ii),  and 4(b)(v) the
sums due pursuant to this Section 4(b) shall be paid in one lump-sum  payable no
later than sixty (60) days after the Date of Termination.  All sums of money due
hereunder   shall  be  subject  to   appropriate   withholding   and   statutory
requirements.  Executive  shall not be required  to  mitigate  the amount of any
payment  provided  for in this  Section  4(b) by  seeking  other  employment  or
otherwise. Notwithstanding anything stated in this Section 4(b) to the contrary,
Company  shall not be  required to provide  medical,  health  and/or  disability
benefits  to the extent  such  benefits  would  duplicate  benefits  received by
Executive in connection with his employment with any new employer.

     The  determination  of the amounts and  benefits  payable to the  Executive
pursuant to Sections  4(b)(i),  4(b)(iii) and 4(b)(iv) (the  "Combined  Amount")
shall first be made by the Company in good faith,  and the Company  shall notify
the  Executive  of the  Combined  Amount as soon as  possible  after the Date of
Termination,  but in no event  later  than  forty-five  (45)  days  prior to the
payment  date of the sums due  under  Section  4(b)(iii)  and  4(b)(iv).  If


                                      E-18
<PAGE>

the Executive disagrees with the Company's determination of the Combined Amount,
then within ten (10) days after the date of such  notification to the Executive,
the Executive shall notify the Company of such disagreement,  the extent of such
disagreement  (the  "Disputed  Amount") and the amount that is  undisputed  (the
"Undisputed  Amount").  The  Undisputed  Amount  shall  be paid in one  lump-sum
payable sixty (60) days after the Date of  Termination,  subject to  appropriate
withholding  and  statutory  requirements.  If the  Company  disagrees  with the
Executive's  determination  of the  Combined  Amount,  then within ten (10) days
after the date of such  notification to the Company,  it shall furnish Executive
with a  written  appraisal  of the  Combined  Amounts  (the  "First  Appraisal")
prepared by an independent certified public accountant regularly employed by the
Company  (the  "First  Appraiser").  If  Executive  disagrees  with the  amounts
determined  pursuant  to the First  Appraisal,  then  within ten (10) days after
notice of the First  Appraisal,  he shall  furnish  the  Company  with a written
appraisal  of the  Combined  Amount  (the  "Second  Appraisal")  prepared  by an
independent  certified public  accountant (the "Second  Appraiser").  Within ten
(10) days after  notice of the Second  Appraisal,  the First  Appraiser  and the
Second  Appraiser  shall meet and shall  endeavor,  within ten (10) days of such
meeting,  to agree upon the  Combined  Amount and  notify  the  Company  and the
Executive thereof; provided,  however, that if they are unable to agree upon the
Combined Amount,  then,  within (10) days of such meeting,  they shall engage an
independent  certified public accountant (the "Third  Appraiser") and notify the
Company and the  Executive of their  engagement  of the Third  Appraiser,  whose
determination of the Combined Amount,  if any, shall be final and conclusive and
binding on the Company and the  Executive.  Within ten (10) days after notice of
such  engagement,  the Third  Appraiser  shall determine the Combined Amount and
notify the Company and the Executive of his determination  (the "Final Amount").
Except for the benefits  described in Sections  4(b)(ii) and 4(b)(v),  the Final
Amount, as adjusted by any prior payment of the Undisputed Amount or any payment
made pursuant to Section  4(b)(i),  shall be paid in one lump-sum payable on the
later of (i) sixty (60) days after the Date of Termination,  or (ii) twenty (20)
days  after  notification  of the  Final  Amount,  in  either  case  subject  to
appropriate  withholding and statutory  requirements;  provided,  however,  that
notwithstanding  the foregoing,  the Executive  shall have the option to decline
the benefits  described in Section 4(b)(ii) no later than ten (10) days prior to
such payment date.

     (c)  Disability  or  Death.  If  the  Executive's   employment  during  the
Employment  Period  is  terminated  at any  time by  reason  of the  Executive's
Disability or death, this Agreement shall terminate without further  obligations
to the Executive, his estate or legal representative, as the case may be, except
that the Company  shall (i) pay to  Executive  within  sixty (60) days after the
Date of  Termination  (A)  amounts  due and owing  under  Sections  4(b)(i)  and
4(b)(iii) and (B)  Executive's  Annual Base Salary for the lesser of the six (6)
month period  following the Date of Termination or the remaining  portion of the
Employment  Period,  reduced in the case of  Disability  by amounts  received by
Executive under any employee disability policy maintained by the Company for the
benefit  of  Executive  and  (ii)  provide   Executive,   his  estate  or  legal
representative,  as the  case may be,  with the  benefits  provided  by  Section
4(b)(ii).

     5. Nonexclusivity of Rights.

     Nothing in this Agreement shall prevent or limit the Executive's continuing
or future participation in any plan, program, policy or practice provided by the
Company and for which the Executive may qualify, nor shall anything herein limit
or otherwise  affect such rights as the Executive may


                                      E-19
<PAGE>

have under any contract or agreement with the Company.  Amounts which are vested
benefits or which the Executive is otherwise entitled to receive under any plan,
policy,  practice or program of or any contract or agreement with the Company at
or subsequent  to the Date of  Termination  shall be payable in accordance  with
such plan,  policy,  practice  or program or contract  or  agreement,  except as
explicitly modified by this Agreement.

     6. Successors; Binding Agreement.

     (a) The Company will require any successor  (whether  direct or indirect by
purchase, merger, consolidation or otherwise, to all or substantially all of the
business and/or assets of the Company) to expressly  assume and agree to perform
this  Agreement in the same manner and to the same extent that the Company would
be required to perform it if no such succession had taken place.

     (b) This  Agreement  shall  inure to the benefit of and be  enforceable  by
Executive's  personal  or  legal  representatives,   executors,  administrators,
successors, heirs, distributees, devisees and legatees.

     7.  Notices.  All  notices,  requests,  demands  and  other  communications
provided for by this  Agreement  shall be in writing and shall be deemed to have
been given when delivered by hand and  acknowledged by receipt or when mailed at
any general or branch  United  States Post Office  enclosed in a  registered  or
certified postpaid envelope and addressed to the address of the respective party
stated  below or to such changed  address as the party may have  provided to the
other party by notice in accordance herewith.

                                  If to the Company:

                                  Osteotech, Inc.
                                  51 James Way
                                  Eatontown, New Jersey 07724
                                  Attention:  Corporate Secretary

                                  With a copy to:

                                  Dorsey & Whitney LLP
                                  250 Park Avenue
                                  New York, NY  10177
                                  Attn:  Kevin T. Collins, Esq.

If to the Executive:

                                  Arthur A. Alfaro
                                  10201 Shrewsbury Run West
                                  Collierville, TN 38017


     8. Miscellaneous.  This Agreement may not be waived, modified or discharged
unless such waiver, modification or discharge is agreed to in writing and signed
by Executive and such officers of the Company as may be specifically  designated
by its Board.  The failure of either  party to this  Agreement  to object to any
breach  by the other  party or the  non-breaching  party's  conduct  or  conduct
forbearance shall not constitute a waiver of that party's rights to enforce this
Agreement.  No waiver by either  party  hereto at any time of any  breach by the
other party hereto of, or  compliance  with,  any


                                      E-20
<PAGE>

condition  or  provision  of this  Agreement to be performed by such other party
shall be deemed a waiver of any  subsequent  breach by such  other  party or any
similar  or  dissimilar  provisions  or  conditions  at the same or any prior or
subsequent time.  Except for that certain  employment  agreement dated as of the
13th day of September,  1999 and entered into by and between the Company and the
Executive (the "Employment Agreement"),  no agreements or representations,  oral
or otherwise, express or implied, with respect to the subject matter hereof have
been made by either party which are not expressly  set forth in this  Agreement.
The  Company  and  Executive  agree  that to the  extent any of the terms of the
Employment  Agreement and this Agreement  conflict,  it is their  intention that
Executive in each case receive the benefits under that  agreement  which is most
favorable  to the  Executive.  In this regard,  it is expressly  agreed that the
terms of this  Agreement  that relate to a Change in Control (as defined in this
Agreement) shall be controlling over the terms of the Employment  Agreement that
relate to a Change in Control.  The validity,  interpretation,  construction and
performance  of this  Agreement  shall be governed by the  internal  laws of the
State of New Jersey, without giving any effect to any conflict of laws.

     9.  Severability.  The invalidity or  unenforceability  of any provision of
this  Agreement  shall not affect the  validity or  enforceability  of any other
provision of this Agreement.

     10.  Survival.  The  obligations of the parties under this Agreement  shall
survive the term of this Agreement.

     11.  EMPLOYMENT  PRIOR TO CHANGE IN CONTROL.  THE EXECUTIVE AND THE COMPANY
ACKNOWLEDGE THAT, EXCEPT AS OTHERWISE PROVIDED IN THE EMPLOYMENT  AGREEMENT,  OR
ANY RENEWAL,  EXTENSION OR REPLACEMENT  THEREOF, THE EMPLOYMENT OF THE EXECUTIVE
BY THE COMPANY IS, AND PRIOR TO THE  COMMENCEMENT  DATE WILL CONTINUE TO BE, "AT
WILL" AND,  PRIOR TO THE  COMMENCEMENT  DATE,  MAY BE  TERMINATED  BY EITHER THE
EXECUTIVE  OR THE  COMPANY AT ANY TIME UPON  SIXTY  (60) DAYS'  PRIOR TO WRITTEN
NOTICE.  MOREOVER, IF PRIOR TO THE COMMENCEMENT DATE, THE EXECUTIVE'S EMPLOYMENT
WITH THE COMPANY  TERMINATES,  THEN THE EXECUTIVE  SHALL HAVE NO FURTHER  RIGHTS
UNDER THIS AGREEMENT.


                                       OSTEOTECH, INC.

                                       By: /s/ Richard W. Bauer
                                           ---------------------------
                                       Name:  Richard W. Bauer
                                       Title: Chief Executive Officer

                                                         and

                                       By: /s/Arthur A. Alfaro
                                           ---------------------------
                                       Name:  Arthur A. Alfaro
                                       Title: President and Chief
                                              Operating Officer

                                      E-21

                                                                   EXHIBIT 10.36

                                  CONFIDENTIAL
                    SETTLEMENT AGREEMENT AND GENERAL RELEASE

     WHEREAS,  the  parties  hereto,  DePuy  AcroMed,   Inc.,  and  DePuy,  Inc.
(collectively "DePuy") and Osteotech,  Inc. ("Osteotech"),  desire to resolve by
settlement  the  litigation  styled  Osteotech  Inc.,  Defendant,   Counterclaim
Plaintiff  and  Third-Party  Plaintiff v. DePuy  Motech,  Inc. and DePuy,  Inc.,
pending as third-party claims in civil action No. CV99-10111-MRP(CTX)  (formerly
CV9868 AHS(EEX)) in the United States District Court for the Central District of
California (the "Litigation"); and

     WHEREAS,  the parties desire to resolve by settlement of the Litigation all
disputes known or posited currently to exist between them, and those that may be
reasonably  contemplated,  relating to DePuy's  sale of the  Dynagraft  products
which are  alleged in the  Litigation  to  infringe  United  States  Patent Nos.
5,290,558  and  5,284,655,  Dynagraft  Gel and  Dynagraft  Putty  (the  "accused
products" or the "accused  Dynagraft  products").  The "accused products" do not
include Dynagraft DBM Granules, Dynagraft Matrix 45 or Dynagraft Matrix 30.

     NOW, THEREFORE, IN CONSIDERATION OF the mutual covenants and agreements set
forth  herein and other good and  valuable  consideration,  DePuy and  Osteotech
MUTUALLY SPECIFY AND AGREE THAT:

     1. Osteotech agrees to execute and file in the form of attached Exhibit A a
stipulated  dismissal  with  prejudice  of all claims and related  requests  for
compensatory and exemplary damages, attorneys' fees, costs and interest expenses
Osteotech  has asserted,  could have asserted or sought leave to assert  against
DePuy in the Litigation arising from or related to DePuy's


                                      E-22
<PAGE>

alleged infringement of United States Patent Nos. 5,290,558 and 5,284,655 caused
by or related to  DePuy's  sale of the  accused  Dynagraft  products.  Upon such
dismissal DePuy will no longer participate in the Litigation, except as required
by law. That  dismissal  shall not be filed with the Court until the time of any
public  disclosure  by Osteotech  pursuant to paragraph 13 below or 4:00 p.m. in
New York on November 11, 1999, whichever is earlier.

     2. Osteotech hereby releases,  acquits, discharges and covenants not to sue
DePuy AcroMed,  Inc., DePuy, Inc., DePuy  Orthopaedics,  Inc., Johnson & Johnson
and their affiliates, parents, subsidiaries,  officers, directors, shareholders,
employees,  agents and  attorneys  (collectively  the "DePuy  Parties")  and any
physicians  and  hospitals  from any and all claims,  causes of action,  rights,
allegations,  liabilities  or  damages  whatsoever  arising  out of the  alleged
infringement  by DePuy or any such  physicians or hospitals of the United States
Patent Nos.  5,290,558 and  5,284,655  patents and any other  applicable  United
States  patents  owned by  Osteotech  caused by or related  to  DePuy's  sale or
promotion of the accused Dynagraft products for the time period through February
4, 2000.

     3. Osteotech hereby releases,  acquits, discharges and covenants not to sue
the DePuy  Parties and any  physicians  and  hospitals  from any and all claims,
causes  of  action,  rights,  allegations,  liabilities  or  damages  whatsoever
relating to or arising from  DePuy's sale or promotion of the accused  Dynagraft
products  for the time period  through  February  4, 2001 based upon  heretofore
undisclosed  existing Osteotech  inventions for which patent protection has been
or may be obtained  ("current patent  applications").  The release  contained in
this  paragraph  3 and in the  previous  paragraph  2 shall  not  apply to or be
effective  with  respect  to any  sale or  promotion  of the  accused  Dynagraft
products  by any of the  DePuy  Parties  after  February  4, 2001 or the sale or
promotion of any other products by any of the DePuy Parties at any time.



                                      E-23
<PAGE>

     4. The DePuy Parties hereby release,  acquit, discharge and covenant not to
sue Osteotech, its affiliates,  subsidiaries, officers, directors, shareholders,
employees, agents and attorneys (collectively, the "Osteotech Parties") from any
and all claims, causes of action,  rights,  allegations,  liabilities or damages
whatsoever  which any of the DePuy Parties has asserted,  could have asserted or
sought leave to assert  against any of the Osteotech  Parties in the  Litigation
arising  out of or related to any sale or  promotion  of the  accused  Dynagraft
products by any of the DePuy Parties.

     5. This  Agreement  is entered  into solely for the purpose of avoiding the
burden and expense of further  litigation  and neither it, nor any statements or
recitations in it, nor any negotiations  leading up to it, is intended to be, or
should be  construed  as, an  admission  of fact or liability on the part of any
party.

     6. In connection with any legal or administrative proceeding related to the
accused  Dynagraft  products,  the DePuy  Parties  will not contest  Osteotech's
claims that United  States  Patent Nos.  5,290,558  and  5,284,655 are valid and
infringed by the accused Dynagraft products.

     7. Except as specifically  provided herein, the parties expressly agree and
understand that this Settlement Agreement does not extend to any other person or
entity  (whether a party to the present  litigation  or not, or that person's or
entity's  agents,  servants,  or  attorneys),   and  that  it  does  not  affect
Osteotech's  rights  against any other person or entity  (whether a party to the
present  litigation or not, or that person's or entity's  agents,  servants,  or
attorneys),  that Osteotech may charge with infringement of United States Patent
Nos.  5,290,558 and/or 5,284,655.  Specifically,  by releasing the DePuy Parties
and  physicians  and  hospitals in this  agreement,  Osteotech is not  releasing
GenSci  Regeneration  Laboratories,   Inc.  or  its  parents,   subsidiaries  or

                                      E-24
<PAGE>

affiliated  companies ("GenSci") or waiving any of its claims against GenSci, or
any other person or entity.

     8. The terms of this Confidential  Settlement  Agreement shall be governed,
construed and enforced in  accordance  with the laws of the State of New Jersey,
without regard to contrary New Jersey conflict of laws provisions.

     9. This Confidential  Settlement Agreement shall be binding upon, and inure
to  the  benefit  of,  the  parties  hereto  and  their  respective  successors,
administrators and assigns.

     10.  Within  ten (10) days of  execution  of this  Confidential  Settlement
Agreement  by both  parties,  DePuy shall pay  Osteotech  the sum of Two Million
Dollars  ($2,000,000.00)  by delivery to  Osteotech  of a certified or cashier's
check or the wire transfer of such funds to an account designated by Osteotech.

     11. In  addition,  DePuy  shall pay  Osteotech a further sum of One Million
Dollars ($1,000,000.00) as follows:

                           $250,000.00 on March 31, 2000;
                           $250,000.00 on June 30, 2000;
                           $250,000.00 on September 30, 2000; and
                           $250,000.00 on December 31, 2000.

However,  with respect to the payments  outlined in this paragraph,  each of the
quarterly  payments  shall be payable only if DePuy sells some  accused  product
during the  quarter  ending on the date on which the  payment  is due.  If DePuy
sells no accused product during a quarter, that quarterly payment is forgiven.



                                      E-25
<PAGE>

     12. The DePuy  Parties  agree to stop selling the accused  products and any
other flowable product that contains  demineralized  osteogenic bone powder in a
polyhydroxy (e.g., Pluronic F127) carrier on the earlier of (a) February 4, 2001
or (b) the end of any quarter in which DePuy owes no  payments  under  Paragraph
11. However,  if Osteotech settles with GenSci and permits GenSci to continue to
manufacture and sell the accused products, then DePuy shall not be bound to stop
selling the accused  products  after February 4, 2001, but shall be free to sell
said products without further payment to Osteotech.

     13. The parties  understand and agree that the terms and conditions of this
Confidential   Settlement   Agreement   and  Release   shall  be  kept  strictly
confidential and shall not be disclosed, or caused to be disclosed, by Osteotech
or DePuy or by any of their officers,  directors,  employees, agents, attorneys,
or by any affiliates, or officers,  directors,  employees,  agents, attorneys of
affiliates,  except as set forth in this  paragraph 13 and except as required by
court  order or law or  regulation.  Osteotech  shall make no  disclosure  until
either  (a) 4:00 p.m.  in New York on the day that DePuy has  advised  Osteotech
that DePuy will disclose the existence of this agreement to GenSci (DePuy agrees
to give Osteotech 24 hours advance notice of its intent to so disclose to GenSci
and  Osteotech  agrees  DePuy may so  disclose  any terms of this  agreement  to
GenSci),  (b) 4:00 p.m. in New York on November 11 or (c) the public  disclosure
of the existence or terms of this  agreement  without the fault of the Osteotech
Parties,  whichever is the earliest.  At that time,  Osteotech may make a public
disclosure  consistent  with  the  terms  of  this  agreement.  After  a  public
disclosure by Osteotech,  DePuy may make public disclosures about this agreement
consistent with the terms of this agreement.

     14. The persons executing this Settlement  Agreement on behalf of Osteotech
and DePuy each represent and warrant that they have full and complete  authority
to do so.



                                      E-26
<PAGE>

     15. DePuy agrees that the breach of this Settlement Agreement by any of the
Depuy  parties  resulting  or  arising  from any such party  continuing  to sell
accused  products or any other  flowable  product  that  contains  demineralized
osteogenic  bone powder in a  polyhydroxy  (e.g.,  Pluronic  F127) carrier after
February  4,  2001,  will  result  in  irreparable  harm to  Osteotech  and that
Osteotech shall have the right to seek immediate  injunctive relief in the event
of such actual or  threatened  breach,  in addition to any other legal  remedies
that  may be  available  to  Osteotech,  and  without  the  need to post a bond.
Notwithstanding  the foregoing,  in any action for  injunctive  relief the DePuy
Parties do not waive or Limit their  rights to assert  defenses  concerning  the
unenforceability  of  paragraph  12 in the event the United  States  Patent Nos.
5,290,558  and  5,284,655 are declared  non-infringed  by the accused  Dynagraft
products,  invalid or  unenforceable  by a court of competent  jurisdiction in a
final, non-appealable judgment.

     16. The parties  declare  and  represent:  (1) No promise,  representation,
inducement or agreement not expressed in this Confidential  Settlement Agreement
has been  made to  either  of them;  (2) They are not  relying  on any  promise,
representation,  inducement  or  agreement  in entering  into this  Confidential
Settlement Agreement except as expressly set forth in this Settlement Agreement;
(3) This Confidential  Settlement Agreement (and its attached Exhibit A) contain
the entire agreement between the parties relating to its subject matter; (4) The
parties have consulted with counsel of their own choosing prior to entering into
this Confidential  Settlement Agreement;  and (5) The terms of this Confidential
Settlement Agreement are contractual and not mere recitals.

     17.  The  parties  agree to  jurisdiction  and venue in the  United  States
District  Court for the District of New Jersey for all  disputes  arising out of
this Agreement.


                                      E-27
<PAGE>

         IN  WITNESS  HEREOF,  this  Settlement  Agreement  is  executed  by the
parties:

DATED: November 2, 1999                     Dated: November 2, 1999

OSTEOTECH, INC.                             DEPUY ACROMED, INC.

By:  /s/Richard W. Bauer                    By: /s/Earl R. Fender, Jr.
     ------------------------------             --------------------------------
       Its: Chief Executive Officer              Its: President


                                            Dated: November 2, 1999

                                            DEPUY, INC.

                                            By: /s/Donald E. Knebel
                                                --------------------------------
                                                  Its: Attorney

APPROVED AS TO SUBSTANCE AND FORM:

DORSEY & WHITNEY, LLP                       BARNES & THORNBURG

By: /s/Kevin T. Collins                     By: /s/Donald E. Knebel
    -------------------------------             --------------------------------
       One of the Attorneys on              One of the Attorneys on
       behalf of Osteotech, Inc.              behalf of DePuy AcroMed, Inc.
                                              and DePuy, Inc.


                                      E-28
<PAGE>


EXHIBIT A
ALAN H. BOON
BERGER, KAHN, SHAFTON, MOSS,
FIGLER SIMON & GLADSTONE
2 Park Place, Suite 650
Irvine, California 92614-8516
Telephone: (949) 474-1880
Facsimile:  (949) 474-7265

Daniel P. Albers
Melissa A. Vallone
BARNES & THORNBURG
200 West Madison - Suite 2610
Chicago, IL 60606
Telephone: (312) 357-1313
Facsimile:  (312) 214-8831
Attorneys for Third Party Defendants
DEPUY, INC. and DEPUY ACROMED, INC.

                          UNITED STATES DISTRICT COURT
                         CENTRAL DISTRICT OF CALIFORNIA

- ------------------------------------------
OSTEOTECH, INC.,                          )
                                          )
                  Defendant, Counterclaim )
                  Plaintiff and Third     )
                  Party Plaintiff         )
                                          )
       v.                                 )   Case No.: CV-99-10111-MRP(CTX)
                                          )
GENSCI REGENERATION SCIENCES, INC.,       )
                                          )
DePuy MOTECH, INC. and DEPUY, INC.,       )
                                          )
                  Third Party Defendants. )
- ------------------------------------------)

                         AGREED FINAL ORDER OF DISMISSAL

     Defendant,  Counterplaintiff  and Third Party  Plaintiff,  Osteotech,  Inc.
("Osteotech") and Third Party Defendants DePuy AcroMed,  Inc.,  incorrectly sued
as  DePuy  Motech,  Inc.  and  DePuy,  Inc.  (collectively,   "DePuy"),  through
settlement negotiations, having compromised and


                                      E-29
<PAGE>

resolved their disputes, and the Court having been advised that a Settlement has
been reached by said parties;

     IT IS HEREBY ORDERED THAT:

     1. Osteotech's Third-Party Complaint against DePuy AcroMed, Inc. and DePuy,
Inc. is dismissed with prejudice;

     2. In approving  this Agreed  Order,  neither  party admits any  liability,
culpability  nor fault with respect to the  allegations in any pleading filed or
sought to be filed in this Action;

     3. Each party shall bear its own costs,  attorneys' fees and other expenses
relative to this Action; and

     4. The Court finds pursuant to Federal Rule of Civil  Procedure  54(b) that
there is no just  reason to delay  enforcement  of or appeal from this Order and
the Court directs the clerk to enter judgment on this Order.


                                      E-30
<PAGE>

     IT IS SO ORDERED:
Dated:____________,1999        Entered: /s/ Mariana P. Pfaelzer
                                        -----------------------------------
                                        The Honorable Mariana P. Pfaelzer
                                        United States District Court Judge
AGREED AS TO FORM:

/s/Mark Sullivan               /s/Donald E. Knebel and /s/Daniel P. Albers
Attorneys for Defendant        Attorneys for Third-Party Defendants
Third-Party Plaintiff          DEPUY ACROMED, INC. (incorrectly sued as
OSTEOTECH, INC.                DEPUY MOTECH, INC.) and DEPUY, INC.

Mark Sullivan                  Donald E. Knebel
Dorsey & Whitney LLP           Daniel P. Albers
650 Town Center Drive          Barnes & Thornburg
Suite 1850                     2600 Chase Plaza
Costa Mesa, CA 92626           10 South LaSalle Street
(714) 662-7300                 Chicago, Illinois 60603
                               (312) 357-1313


                                      E-31

<TABLE> <S> <C>


<ARTICLE>                     5
<LEGEND>
This  schedule  contains  summary  financial   information  extracted  from  the
Osteotech,  Inc. and Subsidiaries Consolidated Balance Sheet as of September 30,
1999 and the Condensed  Consolidated Statement of Operations for the nine months
ended  September  30, 1999 and is qualified in its entirety by reference to such
financial statements.
</LEGEND>

<S>                             <C>
<PERIOD-TYPE>                   9-MOS
<FISCAL-YEAR-END>                                 DEC-31-1999
<PERIOD-END>                                      SEP-30-1999
<CASH>                                             17,258,000
<SECURITIES>                                        3,946,000
<RECEIVABLES>                                      11,054,000
<ALLOWANCES>                                          134,000
<INVENTORY>                                         3,547,000
<CURRENT-ASSETS>                                   45,143,000
<PP&E>                                             42,191,000
<DEPRECIATION>                                     13,177,000
<TOTAL-ASSETS>                                     79,770,000
<CURRENT-LIABILITIES>                              11,905,000
<BONDS>                                             3,624,000
                                       0
                                                 0
<COMMON>                                              140,000
<OTHER-SE>                                         63,666,000
<TOTAL-LIABILITY-AND-EQUITY>                       79,770,000
<SALES>                                             2,163,000
<TOTAL-REVENUES>                                   55,877,000
<CGS>                                               1,285,000
<TOTAL-COSTS>                                      41,882,000
<OTHER-EXPENSES>                                            0
<LOSS-PROVISION>                                            0
<INTEREST-EXPENSE>                                     55,000
<INCOME-PRETAX>                                    16,381,000
<INCOME-TAX>                                        6,631,000
<INCOME-CONTINUING>                                 9,750,000
<DISCONTINUED>                                              0
<EXTRAORDINARY>                                             0
<CHANGES>                                                   0
<NET-INCOME>                                        9,750,000
<EPS-BASIC>                                               .70
<EPS-DILUTED>                                             .67



</TABLE>


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