SMITH BARNEY SERIES FUND
497, 1995-05-17
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                SMITH BARNEY SERIES FUND INC.
                        (the "Fund")
                Supplement to Prospectus and
             Statement of Additional
             Information
                    dated April 29, 1995
                    
                    
      On  May 15, 1995, Smith Barney Mutual Funds
Management Inc. assumed responsibility for all
administrative functions for  the  Fund, including
functions previously performed  by The  Boston Company
Advisors, Inc. ("Boston Advisors").
As
of  that  date, Boston Company Advisors  ceased to serve
as sub-administrator to the Fund.

       Also   as  of   May  15,  1995,  PNC  Bank,
National Association assumed responsibility as the
custodian for  the Fund.
As  of  that  date, Boston Safe  Deposit  and  Trust
Company, an affiliate of Boston Advisors, ceased to serve
as the  Fund's  custodian.  PNC Bank, National
Association  is located at   17th  and  Chestnut  Streets,
Philadelphia,
Pennsylvania.


_________________________________
Supplement dated May 17, 1995





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