<PAGE>
PROSPECTUS SUPPLEMENT FILED PURSUANT TO 424(b)(3) and (c)
(TO PROSPECTUS DATED AUGUST 28, 2000) REGISTRATION No. 333-37742
COR THERAPEUTICS, INC.
$300,000,000 Principal Amount 5.00% Convertible Subordinated Notes due March 1,
2007
and Shares of Common Stock Issuable upon Conversion of the Notes
________________
This prospectus supplement should be read in conjunction with the prospectus
dated August 28, 2000, which is to be delivered with the prospectus supplement.
See "Risk Factors" beginning on page 5 of the prospectus to read about factors
you should consider before purchasing the notes or our common stock.
Neither the Securities and Exchange Commission nor any other regulatory body
has approved or disapproved of these securities or passed upon the accuracy or
adequacy of this prospectus. Any representation to the contrary is a criminal
offense.
________________
The table, including related notes, appearing in the prospectus under the
heading "Selling Security Holders" is superceded by the following table,
including related notes:
<TABLE>
<CAPTION>
COMMON
STOCK OWNED
SHARES OF AFTER
PRINCIPAL AMOUNT COMMON STOCK COMPLETION
OF NOTES BENEFICIALLY COMMON STOCK OF
NAME OFFERED(1) OWNED(2) OFFERED OFFERING
--------------------------------------- ---------- -------- ------- --------
<S> <C> <C> <C> <C>
AAM/Zazove Institutional Income Fund, L.P. 625,000 18,502 18,502 0
AIG/National Union Fire Insurance 1,330,000 39,376 39,376 0
AIG SoundShore Holdings Ltd. 3,500,000 103,620 103,620 0
AIG SoundShore Opportunity Holdings Fund Ltd 3,500,000 103,620 103,620 0
AIG SoundShore Strategic Holdings Fund Ltd 1,000,000 29,606 29,606 0
Allstate Insurance Company 1,120,000 49,558(3) 33,158 16,400
Aloha Airlines Pilots Retirement Trust 75,000 2,220 2,220 0
Aloha Airlines Non-Pilots Pension Trust 130,000 3,848 3,848 0
Argent Classic Convertible Arbitrage Fund L.P. 6,250,000 185,034 185,034 0
Argent Classic Convertible Arbitrage Fund (Bermuda) L.P. 9,500,000 281,253 281,253 0
Argent Convertible Arbitrage Fund Ltd 2,000,000 59,210 59,210 0
Associated Electric & Gas Insurance Service Limited 500,000 14,803 14,803 0
Boulder II Limited 7,750,000 229,442 229,442 0
BP. Amoco Plc. Master Trust 4,069,000 120,464 120,464 0
Castle Convertible Fund, Inc. 500,000 14,803 14,803 0
C&H Sugar Company, Inc. 205,000 6,068 6,068 0
CIBC World Markets (4) 3,250,000 96,218 96,218 0
The Common Fund for Non-Profit Organizations 45,000(5) 1,747 1,332 415(5)
Credit Suisse First Boston Corporation 7,500,000 222,042 222,042 0
DaimlerChrysler Corporation Emp. #1 Pension Plan dtd
4/1/89 1,946,000 57,612 57,612 0
Deutsche Bank Securities Inc. 67,400,000 1,995418 1,995,418 0
Employee Benefit Convertible Securities Fund 160,000 4,737 4,737 0
Estate of James Campbell 1,161,000 34,372 34,372 0
</TABLE>
1.
<PAGE>
<TABLE>
<S> <C> <C> <C> <C>
Franklin & Marshall College 134,000 3,966 3,966 0
GE Pension Trust 964,000 28,538 28,538 0
Georges et/ou Maya Andraos 160,000 2,960 2,960 0
GLG Market Neutral Fund 5,000,000 148,028 148,028 0
Goldman Sachs & Co.(6) 2,741,000 81,149 81,149 0
Grace Brothers, LTD 1,500,000 44,408 44,408 0
Hawaiian Airlines Employees Pension Plan - IAM 110,000 3,256 3,256 0
Hawaiian Airlines Pension Plan for Salaried Employees 30,000 888 888 0
Hawaiian Airlines Pilots Retirement Trust 180,000 5,328 5,328 0
Highbridge International LLC 27,900,000 825,996 825,996 0
HT Insight Convertible Securities Fund 300,000 8,880 8,880 0
Island Holdings 75,000 2,220 2,220 0
ITG. Inc. 220,000 6,512 6,512 0
Jefferies & Company 500,000 14,803 14,803 0
JMG Capital Partners, LP 10,000,000 296,056 296,056 0
JMG Triton Offshore Fund, Ltd. 14,000,000 414,478 414,478 0
J.P. Morgan Securities Inc. 237,000 7,017 7,017 0
KBC Financial Products 4,500,000 133,225 133,225 0
LDG Limited 125,000 3,700 3,700 0
Legion Strategies Ltd. 45,000(7) 1,776 1,332 444(7)
Levco Alternative Fund, Ltd. 999,000(8) 38,635 29,576 9,059(8)
Lexington Vantage Fund 50,000 1,480 1,480 0
Lipper Convertibles, L.P. 5,400,000 159,870 159,870 0
Lipper Offshore Convertibles, L.P. 500,000 14,803 14,803 0
Lyxor Master Fund 2,300,000 68,092 68,092 0
Mainstay Convertible Fund 1,250,000 37,007 37,007 0
McMahan Securities Company L.P. 134,000 3,967 3,967 0
Museum of Fine Arts, Boston 20,000 592 592 0
Nateo Chemical Company 525,000 15,542 15,542 0
Nations Convertible Securities Fund 2,840,000 84,080 84,080 0
New York Life Insurance Company 13,550,000 401,154 401,154 0
Onex Industrial Partners Limited 3,750,000 111,020 111,020 0
Parker-Hannifin Corporation 35,000 1,036 1,036 0
Pebble Capital, Inc. 3,500,000 103,618 103,618 0
Penn Treaty Network America Insurance Company 156,000 4,618 4,618 0
Pioneer High Yield Fund 300,000 8,880 8,880 0
ProMutual 74,000 2,190 2,190 0
Purchase Associates, L.P. 411,000(9) 16,105 12,168 3,937(9)
Putnam Asset Allocation Funds-Balanced Portfolio 139,000 4,114 4,114 0
Putnam Asset Allocation Funds-Conservative Portfolio 89,000 2,634 2,634 0
Putnam Balanced Retirement Fund 39,000 1,154 1,154 0
Putnam Convertible Income-Growth Trust 2,024,000 59,920 59,920 0
Putnam Convertible Opportunities and Income Trust 59,000 1,746 1,746 0
Queen's Health Plan 45,000 1,332 1,332 0
R/2/ Investments, LDC 31,050,000 919,254 919,254 0
Robertson Stephens(10) 10,000,000 296,056 296,056 0
Salomon Brothers Asset Management , Inc. 7,000,000 207,238 307,238 0
San Diego County Employees Retirement Association 2,595,000 76,827 76,827 0
Silvercreek Limited Partnership 4,000,000 118,422 118,422 0
Southern Farm Bureau Life Insurance - FRIC 650,000 19,242 19,242 0
Starvest Combined Portfolio 1,690,000 50,033 50,033 0
State of Oregon/SAIF Corporation 6,425,000 190,216 190,216 0
Tribeca Investment L.L.C 5,000,000 148,028 148,028 0
TQA Master Fund, Ltd. 1,850,000 49,220 49,220 0
TQA Master Plus Fund, Ltd. 400,000 11,821 11,842 0
University of Rochester 19,000 562 562 0
Van Kampen Harbor Fund 4,250,000 125,824 125,824 0
Zurich HFR Master Hedge Fund Index Ltd 150,000 4,440 4,440 0
Zurich HFR Master Hedge Fund Index Ltd Global 100,000 2,961 2,961 0
Zurich HFR Mstr Hdg Fund 75,000 2,220 2,220 0
</TABLE>
(1) Unless otherwise noted, the principal amount offered equals the principal
amount beneficially owned.
(2) Unless otherwise noted, represents shares of common stock issuable upon
conversion of notes.
2.
<PAGE>
(3) Includes 8,200 shares held by Allstate Insurance Company, 1,000 shares held
by Allstate Life Insurance Company, 1,800 shares held by Agents Pension
Plan and 5,400 shares held by Allstate Retirement Plan.
(4) CIBC World Markets was an initial purchaser of the notes from us. CIBC
World Markets purchased the notes listed on this table for its own account
and not for purposes of distribution.
(5) Selling Security Holder beneficially owns an additional $14,000 principal
amount of the notes and the shares of common stock issuable upon conversion
thereof, which are not being offered hereby.
(6) Goldman, Sachs & Co. was an initial purchaser of the notes from us.
Goldman Sachs purchased the notes listed on this table in the after-market
for its own account and not for purposes of distribution.
(7) Selling Security Holder beneficially owns an additional $15,000 principal
amount of the notes and the shares of common stock issuable upon conversion
thereof, which are not being offered hereby.
(8) Selling Security Holder beneficially owns an additional $306,000 principal
amount of the notes and the shares of common stock issuable upon conversion
thereof, which are not being offered hereby.
(9) Selling Security Holder beneficially owns an additional $133,000 principal
amount of the notes and the shares of common stock issuable upon conversion
thereof, which are not being offered hereby.
(10) Robertson Stephens was an initial purchaser of the notes from us.
Robertson Stephens purchased the notes listed on this table for its own
account and not for purposes of distribution.
The date of this Prospectus Supplement is November 15, 2000.
3.
