<PAGE> 1
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
FORM 10-C
REPORT BY ISSUER OF SECURITIES QUOTED ON NASDAQ
INTERDEALER QUOTATION SYSTEM
FILED PURSUANT TO SECTION 13 OR 15 (d) OF THE
SECURITIES EXCHANGE ACT OF 1934 AND RULES 13a-17
AND 15d-17 THEREUNDER
Vertex Pharmaceuticals Incorporated
- --------------------------------------------------------------------------------
(Exact name of issuer as specified in charter)
130 Waverley Street
- --------------------------------------------------------------------------------
(Address of principal executive offices)
Issuer's telephone number, including are code (617) 577-6000
-----------------------------------
I. CHANGE IN NUMBER OF SHARES OUTSTANDING
Indicate any change (increase or decrease) of five percent or more in the number
of shares outstanding:
1. Title of security Common Stock, $.01 par value per share
------------------------------------------------------------
2. Number of shares outstanding before the change 17,358,458
-------------------------------
3. Number of shares outstanding after the change 20,808,458
--------------------------------
4. Effective date of change August 14, 1996
-----------------------------------------------------
5. Method of change: Specify method (such as merger, acquisition, exchange,
distribution, stock split, reverse split, acqusition of stock for treasury,
etc.) Public Offering
---------------------------------------------------------------------------
- --------------------------------------------------------------------------------
Give brief description of transaction 3,450,000 shares of Common Stock sold
---------------------------------------
in a firm underwritten public offering
---------------------------------------
II. CHANGE IN NAME OF ISSUER
1. Name prior to change
---------------------------------------------------------
2. Name after change
------------------------------------------------------------
3. Effective date of charter amendment changing name
----------------------------
4. Date of shareholder approval of change, if required
--------------------------
Date August 15, 1996 /s/ Thomas G. Auchincloss, Jr.
--------------------------- -----------------------------------------
Senior Director of Finance and Treasurer
-----------------------------------------
(Officer's signature and title)