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EXHIBIT 23.1
CONSENT OF INDEPENDENT ACCOUNTANTS
We hereby consent to the incorporation by reference in this Registration
Statement on Form S-3 of our report dated February 16, 2000, except as to the
information in Note R for which the date is February 28, 2000, relating to
the financial statements, which appear in Vertex Pharmaceuticals
Incorporated's Annual Report on Form 10-K for the year ended December 31,
1999. We also consent to the reference to us under the heading "Independent
Accountants" in such Registration Statement.
/s/ PricewaterhouseCoopers LLP
Boston, Massachusetts
November 10, 2000
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