VERTEX PHARMACEUTICALS INC / MA
8-K, 2000-09-14
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                 --------------


                                    FORM 8-K

                                 CURRENT REPORT

                         PURSUANT TO SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                                 --------------



Date of Report (Date of earliest event reported):  September 13, 2000

                       Vertex Pharmaceuticals Incorporated
             (Exact name of registrant as specified in its charter)

<TABLE>
<S>                                  <C>                           <C>
      Massachusetts                  000-19319                     04-3039129

-----------------------       --------------------           -------------------
(State or other               (Commission                    (IRS Employer
jurisdiction of               File Number)                   Identification No.)
incorporation)
</TABLE>

                               130 WAVERLY STREET
                               CAMBRIDGE, MA 02139
               ---------------------------------------------------
               (Address of principal executive offices) (Zip Code)

Registrant's telephone number, including area code: (617) 577-6000

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                                  Page 1 of 6 pages

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ITEM 5.   OTHER EVENTS.

         On September 13, 2000, we publicly disseminated a press release
announcing our sale of $300 million of Convertible Subordinated Notes due
September 2007. The information contained in the press release is
incorporated herein by reference and filed as Exhibit 99.1 hereto.

ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

(c)      Exhibits.

99.1     Press Release dated September 13, 2000, "Vertex Pharmaceuticals
         Raises $300 Million in Convertible Subordinated Debt Placement."


                                  Page 2 of 6 pages



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                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                          VERTEX PHARMACEUTICALS INCORPORATED
                                          (Registrant)

Date:  September 13, 2000                  By: /s/ Thomas G. Auchincloss, Jr.
                                              ---------------------------------
                                              Name: Thomas G. Auchincloss, Jr.
                                              Title: Vice President, Finance


                                  Page 3 of 6 pages



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                                  EXHIBIT INDEX

Exhibit                                                     Sequential
Number             Description                              Page Number
-------            -----------                              -----------
99.1               Press Release dated September                 5
                   13, 2000, "Vertex Pharmaceuticals
                   Raises $300 Million in Convertible
                   Subordinated Debt Placement."


                                  Page 4 of 6 pages






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