VERTEX PHARMACEUTICALS INC / MA
8-K, 2000-09-15
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION

                             Washington, D.C. 20549

                                 --------------


                                    FORM 8-K

                                 CURRENT REPORT

                         PURSUANT TO SECTION 13 OR 15(D)
                     OF THE SECURITIES EXCHANGE ACT OF 1934

                                 --------------



Date of Report (Date of earliest event reported):  September 15, 2000

                       Vertex Pharmaceuticals Incorporated
             (Exact name of registrant as specified in its charter)

<TABLE>
<S>                                  <C>                           <C>
      Massachusetts                  000-19319                     04-3039129

-----------------------       --------------------           -------------------
(State or other               (Commission                    (IRS Employer
jurisdiction of               File Number)                   Identification No.)
incorporation)
</TABLE>

                               130 WAVERLY STREET
                               CAMBRIDGE, MA 02139
               ---------------------------------------------------
               (Address of principal executive offices) (Zip Code)

Registrant's telephone number, including area code: (617) 577-6000

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                                  Page 1 of 6 pages

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ITEM 5.   OTHER EVENTS.

         On September 15, 2000, we publicly disseminated a press release
announcing that we are calling our $175 million aggregate principal amount of
Convertible Subordinated Notes due March 2007 for redemption on October 5,
2000. The information contained in the press release is incorporated herein
by reference and filed as Exhibit 99.1 hereto.

ITEM 7.  FINANCIAL STATEMENTS, PRO FORMA FINANCIAL INFORMATION AND EXHIBITS.

(c)      Exhibits.

99.1     Press Release dated September 15, 2000, "Vertex Pharmaceuticals
         Calls for Redemption of Convertible Subordinated Notes due March
         2007."


                                  Page 2 of 6 pages



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                                   SIGNATURES

         Pursuant to the requirements of the Securities Exchange Act of 1934,
the Registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                          VERTEX PHARMACEUTICALS INCORPORATED
                                          (Registrant)

Date:  September 15, 2000                  By: /s/ Thomas G. Auchincloss, Jr.
                                              ---------------------------------
                                              Name: Thomas G. Auchincloss, Jr.
                                              Title: Vice President, Finance


                                  Page 3 of 6 pages



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                                  EXHIBIT INDEX

Exhibit                                                     Sequential
Number             Description                              Page Number
-------            -----------                              -----------
99.1               Press Release dated September                 5
                   15, 2000, "Vertex Pharmaceuticals
                   Calls for Redemption of Convertible
                   Subordinated Notes due March 2007."


                                  Page 4 of 6 pages






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