BIOSPECIFICS TECHNOLOGIES CORP
10KSB/A, 1999-05-18
PHARMACEUTICAL PREPARATIONS
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                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D. C. 20549

                              FORM 10-KSB/A

(Mark One)
      [ X ]    ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF
               THE SECURITIES EXCHANGE ACT OF 1934

For the fiscal year ended  January 31, 1999
                           ----------------

      [   ]    TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
               SECURITIES EXCHANGE ACT OF 1934

For the transition period from ______________ to ______________

Commission file number 0-19879

                         BIOSPECIFICS TECHNOLOGIES CORP.
                 (Name of small business issuer in its charter)
<TABLE>
<CAPTION>
                         Delaware                                                      11-3054851                 
                         --------                                                      ----------                 
<S>                                                                           <C> 
(State or other jurisdiction of incorporation or organization)             (I.R.S. Employer Identification No.)

  35 Wilbur Street, Lynbrook, New York                                                  11563
  ------------------------------------                                                  -----
(Address of principal executive offices)                                              (Zip Code)
</TABLE>

Issuer's telephone number, including area code:  (516) 593-7000  
                                                 --------------

Securities registered pursuant to Section 12(b) of the Act: None Securities
registered pursuant to Section 12(g) of the Act:

                          Common Stock, par value $.001
                          -----------------------------

               Check whether the Issuer (1) filed all reports required to be
filed by Section 13 or 15(d) of the Exchange Act during the past 12 months (or
for such shorter period that the registrant was required to file such reports),
and (2) has been subject to such filing requirements for the past 90 days.
Yes   [X]    No __ 

               Check if there is no disclosure of delinquent filers in response
to Item 405 of Regulation S-B contained in this form and no disclosure will be
contained, to the best of Registrant's knowledge, in definitive proxy or
information statements incorporated by reference in Part III of this Form 10-KSB
or any amendment to this Form 10-KSB. [ ]

               Issuer's revenues for its most recent fiscal year were
$7,062,000. The aggregate market value of common voting stock held by
non-affiliates of the Issuer was approximately $5,530,000 computed by reference
to the last sale price at which the stock was sold on April 14, 1999 as reported
by Nasdaq. As of April 14, 1999, 4,565,866 shares of common stock were
outstanding.

                       DOCUMENTS INCORPORATED BY REFERENCE

               The information required in Part III by Items 9, 10, 11, and 12
is incorporated by reference to the Registrant's proxy statement in connection
with the 1999 annual meeting of shareholders, which will be filed by the
Registrant within 120 days after the close of its fiscal year.

                                       1
<PAGE>
                                     PART IV

      ITEM 13. EXHIBITS, LISTS AND REPORTS ON FORM 8-K.

      (a)   Exhibits    Filed

      Exhibit 3.1      Certificate of Amendment of Certificate of Incorporation
                       of Registrant, as amended. (Previously filed with
                       Registrant's Registration Statement on Form S-18
                       "Registration Statement" and incorporated herein by
                       reference.)

      Exhibit 3.2      Registrant's by-laws as amended. (Previously filed as
                       Exhibit 3.2 and 3.2(a) to Registrant's Registration
                       Statement and incorporated herein by reference.)

      Exhibit 4.1      Copy of Promissory Note executed by Edwin H. Wegman
                       in favor of Advance Biofactures Corporation. (Previously
                       filed as Exhibit 28.1 to Registrant's Registration
                       Statement and incorporated herein by reference.)

      Exhibit 4.2      Copy of Promissory Note executed by Edwin H. Wegman in
                       favor of Sherman C. Vogel and Clarification of Loan
                       executed by Edwin H. Wegman, Sherman C. Vogel, and
                       Advance Biofactures Corporation. (Previously filed as
                       Exhibit 28.2 to Registrant's Registration Statement and
                       incorporated herein by reference.)

      Exhibit 4.3      Copy of Promissory Note executed by Advance Biofactures
                       Corporation in favor of Myron E. Wegman. (Previously
                       filed as Exhibit 28.3 to Registrant's Registration
                       Statement and incorporated herein by reference.)

      Exhibit 10.1     Form of 1991 Stock Option Plan of the Registrant.
                       (Previously filed as Exhibit 10.1 to Registrant's
                       Registration Statement and incorporated herein by
                       reference.)

      Exhibit 10.2     Form of 1993 Stock Option Plan of Registrant. (Previously
                       filed on the Registrant's Form S-8 Registration No.
                       33-95116 dated August 27, 1995 and incorporated herein by
                       reference.)

      Exhibit 10.3     Copy of Agreement between Advance Biofactures Corporation
                       and Knoll Pharmaceutical Company, without exhibits.
                       (Previously filed as exhibit 10.3 to Registrant's 10-KSB
                       for the year ended January 31, 1995 and incorporated
                       herein by reference.)

      Exhibit 10.4     Copy of Lease between Advance Biofactures Corporation and
                       the Wilbur Street Corporation. (Previously filed as
                       exhibit 10.4 to Registrant's 10-KSB for the year ended
                       January 31, 1998 and incorporated herein by reference.)

      Exhibit 10.5     Copy of Lease between the Curacao Industrial and
                       International Trade Development Company (Curinde) N.V.
                       and Advance Biofactures Corporation of Curacao, N.V.
                       (English translation). (Previously filed as Exhibit 10.5
                       to Registrant's Registration Statement and incorporated
                       herein by reference.)

      Exhibit 10.6     Copy of Agreement between Advance Biofactures of Curacao,
                       N.V. and a Swiss company regarding a license for
                       Nucleolysin(R) for Switzerland and Italy, without
                       exhibits. (Previously filed as Exhibit 10.7 to
                       Registrant's Registration Statement and incorporated
                       herein by reference.)

      Exhibit 10.7     Copy of Agreement between Advance Biofactures Corporation
                       and Bernard J. Sussman, as amended. (Previously filed as
                       Exhibit 10.8 to Registrant's Registration Statement and
                       incorporated herein by reference.)

      Exhibit 10.8     Copy of Agreement between Advance Biofactures of Curacao,
                       N.V. and physician regarding testing of Nucleolysin(R).
                       (Previously filed as Exhibit 10.9 to Registrant's
                       Registration Statement and incorporated herein by
                       reference.)
                                       2
<PAGE>

      Exhibit 10.9     Form of Financial Consulting Agreement between the
                       Company and S.D. Cohn & Co., Inc.

      Exhibit 10.10    Copy of Agreement between Bio-Specifics N.V. (a
                       wholly-owned subsidiary of Advance Biofactures of
                       Curacao, N.V.) and Sheldon R. Pinnell, MD. (Previously
                       filed as Exhibit 10.17 to Registrant's Registration
                       Statement and incorporated herein by reference.)

      Exhibit 10.11    Copy of Employment Agreement with Dr. Rainer Friedel
                       (English summary attached). (Previously filed as exhibit
                       10.18 to Registrant's 10-KSB for the year ended January
                       31, 1996 and incorporated herein by reference.)

      Exhibit 10.12    Copy of agreement to extend expiration of Underwriter's
                       warrants and Assignee of Warrants among Registrant, S.D.
                       Cohn & Co., and John C. Dello- Iacono. (Previously filed
                       as exhibit 10.19 to Registrant's 10-KSB for the year
                       ended January 31, 1996 and incorporated herein by
                       reference.)

      Exhibit 10.13    Copy of Collagenase ABC license agreement between Advance
                       Biofactures of Curacao, N.V. and an Italian company,
                       without exhibits. (Previously filed as exhibit 29.1 to
                       Registrant's 10-KSB for the year ended January 31, 1995
                       and incorporated herein by reference.)

      Exhibit 10.14    Copy of Collagenase ABC license agreement between Advance
                       Biofactures of Curacao, N.V. and a Swiss company, without
                       exhibits. (Previously filed as exhibit 29.2 to
                       Registrant's 10-KSB for the year ended January 31, 1995
                       and incorporated herein by reference.)

      Exhibit 10.15    Copy of Promissory Note executed by Edwin H. Wegman in
                       favor of Advance Biofactures Corp. (Previously filed as
                       exhibit 29.3 to Registrant's 10-KSB for the year ended
                       January 31, 1995 and incorporated herein by reference.)

      Exhibit 10.16    Copy of Consulting Agreement between BioSpecifics
                       Technologies Corp. and Stephen A. Vogel. (Previously
                       filed as exhibit 10.23 to Registrant's 10-KSB for the
                       year ended January 31, 1998 and incorporated herein by
                       reference.)

      Exhibit 10.17    Form of 1997 Stock Option Plan of Registrant. (Previously
                       filed on the Registrant's Form S- 8 Registration No.
                       333-36485 dated September 26, 1997 and incorporated
                       herein by reference.)

      Exhibit 22       Subsidiaries of the Registrant. (Previously filed as
                       exhibit 22 to Registrant's 10-KSB for the year ended
                       January 31, 1996 and incorporated herein by reference.)

      Exhibit 23.1     Consent of KPMG LLP.

      Exhibit 27.1     Financial Data Schedule*

      -----------------------------
      *        Filed herewith

      (b)      Reports on Form 8-K

               None.


                                       3

<PAGE>
                                   SIGNATURES

                       In accordance with Section 13 or 15(d) of the Securities
      Exchange Act of 1934, the Registrant caused this report to be signed on
      its behalf by the undersigned, thereunto duly authorized.

                                      BIOSPECIFICS TECHNOLOGIES CORP.
                                      (Registrant)


      Date:    May 17, 1999           By: /s/Edwin H. Wegman                    
                                         ---------------------------------------
                                         Edwin H. Wegman, Chairman and President


                       In accordance with the Securities Exchange Act, this
      report has been signed below by the following persons on behalf of the
      Registrant and in the capacities and on the dates indicated.


<TABLE>
<CAPTION>
<S>                                    <C>                                                      <C>  
  Edwin H. Wegman                      Chairman of the Board, President and                     May 17, 1999
  ---------------------                Director (Principal Executive Officer)
  Edwin H. Wegman                     
                                                                                                May 17, 1999
  Albert Horcher                       Secretary, Treasurer, Principal Financial
  ---------------------                and Chief Accounting Officer
  Albert Horcher
                                                                                                May 17, 1999
  Thomas L. Wegman                     Executive Vice President and Director
  --------------------
  Thomas L. Wegman
                                                                                                May 17, 1999
  Paul A. Gitman, MD.                  Director
  --------------------
  Paul A. Gitman, MD.
                                                                                                May 17, 1999
  Henry Morgan                         Director
  --------------------
  Henry Morgan
                                                                                                May 17, 1999
  Sherman C. Vogel                     Director
  --------------------
  Sherman C. Vogel
                                                                                                May 17, 1999
  Rainer Friedel                       Director
  --------------------
  Rainer Friedel

</TABLE>

                                       4



<TABLE> <S> <C>

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<PERIOD-TYPE>                    12-MOS
<FISCAL-YEAR-END>                              JAN-31-1999  
<PERIOD-START>                                 FEB-01-1998  
<PERIOD-END>                                   JAN-31-1999  
<CASH>                                           5,086,725   
<SECURITIES>                                     2,102,951   
<RECEIVABLES>                                    1,202,003   
<ALLOWANCES>                                             0   
<INVENTORY>                                      1,488,525   
<CURRENT-ASSETS>                                   135,622   
<PP&E>                                           3,160,064   
<DEPRECIATION>                                   2,446,348   
<TOTAL-ASSETS>                                  11,376,543   
<CURRENT-LIABILITIES>                            1,445,976   
<BONDS>                                                  0   
                                    0   
                                              0   
<COMMON>                                             4,891   
<OTHER-SE>                                      11,401,516   
<TOTAL-LIABILITY-AND-EQUITY>                    11,376,543   
<SALES>                                          7,061,884   
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<CGS>                                            2,250,945   
<TOTAL-COSTS>                                    2,250,945   
<OTHER-EXPENSES>                                 2,050,049   
<LOSS-PROVISION>                                         0   
<INTEREST-EXPENSE>                                   6,983   
<INCOME-PRETAX>                                  1,419,508   
<INCOME-TAX>                                       139,300   
<INCOME-CONTINUING>                              1,239,708   
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<CHANGES>                                                0   
<NET-INCOME>                                     1,239,708   
<EPS-PRIMARY>                                         0.26   
<EPS-DILUTED>                                         0.26   
                                                             

</TABLE>


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