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<PAGE> 1 EXHIBIT 16.1 September 29, 2000 Securities and Exchange Commission 450 Fifth Street, N.W. Washington, DC 20549 Gentlemen: We have read Item 4 of Form 8-k dated September 29, 2000, of Eco Soil Systems, Inc. and are in agreement with the statements contained in the first, second and fourth paragraphs on page 2 therein. We have no basis to agree or disagree with other statements of the registrant contained therein. Ernst & Young LLP San Diego, California
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