BIOTIME INC
DEF 14A, 1997-04-24
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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                              [BIOTIME LETTERHEAD]



                                                  April  23, 1997


Dear Shareholder:

   
     You are cordially invited to attend the 1996 Annual Meeting of Shareholders
of BioTime, Inc. which will be held on Friday, May 23, 1997 at 10:00 a.m. at the
Ritz-Carlton Hotel, 600 Stockton Street, San Francisco, California.
    
   
     The Notice and Proxy  Statement  on the  following  pages  contain  details
concerning  the business to come before the Meeting.  Management  will report on
current  operations and there will be an opportunity  for discussion  concerning
the  Company and its  activities.  Please sign and return your proxy card in the
enclosed  envelope to ensure that your shares will be  represented  and voted at
the  meeting  even if you  cannot  attend.  You are urged to sign and return the
enclosed proxy card even if you plan to attend the meeting.
    
     I look  forward to  personally  meeting  all  shareholders  who are able to
attend.



                                           Paul Segall, Ph. D.
                                           President and Chief Executive Officer

<PAGE>



                    NOTICE OF ANNUAL MEETING OF SHAREHOLDERS

                             To Be Held May 23, 1997
   
     NOTICE IS HEREBY GIVEN that the Annual Meeting of  Shareholders of BioTime,
Inc.  (the  "Company")  will be held at the  Ritz-Carlton  Hotel,  600  Stockton
Street,  San  Francisco,  California,  on May 23,  1997 at  10:00  a.m.  for the
following purposes:

    
   
     1.    To elect seven (7)  directors of the Company to hold office until the
next Annual Meeting of Shareholders  and until their  respective  successors are
duly elected and qualified;

     2.    To amend the Company's  1992 Employee Stock Option Plan by increasing
the number of shares available under the Plan.

     3.    To amend the  Company's  Articles of  Incorporation  to increase  the
number of authorized common shares, no par value,  available for issuance in the
future.

     4.    To ratify the appointment of Deloitte & Touche LLP as the independent
accountants of the Company for the fiscal year ending June 30, 1997; and

     5.    To  transact  such other  business  as may  properly  come before the
meeting or any adjournments of the meeting.

     The Board of Directors has fixed the close of business on Wednesday,  April
16, 1997, as the record date for  determining  shareholders  entitled to receive
notice of and to vote at the Annual Meeting or any  postponement  or adjournment
thereof.

     Whether or not you expect to attend the meeting in person, you are urged to
sign and date the  enclosed  form of proxy and return it  promptly  so that your
shares of stock may be  represented  and voted at the meeting.  If you should be
present at the meeting, your proxy will be returned to you if you so request.


                                             By Order of the Board of Directors,



                                             Judith Segall
                                             Vice President and Secretary




    
   
Berkeley, California
April 23, 1997
    

<PAGE>



                                 PROXY STATEMENT

                         ANNUAL MEETING OF SHAREHOLDERS

                           To Be Held on May 23, 1997
   
        The  accompanying  proxy  is  solicited  by the  Board of  Directors  of
BioTime,  Inc., a California corporation (the "Company" or "BioTime") having its
principal offices at 935 Pardee Street,  Berkeley,  California 94710, for use at
the Annual Meeting of  Shareholders of the Company (the "Meeting") to be held at
10:00 a.m.  on Friday,  May 23, 1997 at the  Ritz-Carlton  Hotel,  600  Stockton
Street, San Francisco, California. Properly executed proxies in the accompanying
form that are received at or before the Meeting will be voted in accordance with
the directions noted on the proxies.  If no direction is indicated,  such shares
will be voted FOR (i) each nominee for election as director,  (ii)  amending the
Company's  1992  Employee  Stock  Option Plan to  increase  the number of shares
available under the Plan, (iii) amending the Company's Articles of Incorporation
to increase  the number of  authorized  common  shares,  no par value,  and (iv)
approval of the appointment of Deloitte & Touche LLP as independent  accountants
for the Company for the fiscal year ending June 30, 1997.

    
   
        The enclosed proxy confers discretionary  authority to vote with respect
to any and all of the  following  matters that may come before the Meeting:  (1)
matters that the Company's  Board of Directors  does not know a reasonable  time
before  the  Meeting  are  to be  presented  at the  Meeting;  and  (2)  matters
incidental to the conduct of the Meeting.  Management does not intend to present
any business  for a vote at the Meeting  other than the matters set forth in the
accompanying  Notice of Annual  Meeting of  Shareholders,  and as of the date of
this Proxy  Statement,  no  shareholder  has  notified  the Company of any other
business that may properly come before the Meeting.  If other matters  requiring
the vote of the  shareholders  properly come before the Meeting,  then it is the
intention of the persons  named in the attached  form of proxy to vote the proxy
held by them in accordance with their judgment on such matters.
    
        Only  shareholders  of record at the close of business on April 16, 1997
are entitled to notice of and to vote at the Meeting.  On that date,  there were
3,203,193  of  the  Company's  Common  Shares  issued  and  outstanding,   which
constitutes the only class of voting securities of the Company outstanding. Each
of the  Company's  Common  Shares is  entitled  to one vote in the  election  of
directors and in all other matters that may be acted upon at the Meeting, except
that  shareholders  may elect to cumulate  votes in the  election of  directors.
Under  cumulative  voting,  each  shareholder  may  give  one  candidate  or may
distribute among two or more  candidates,  a number of votes equal to the number
of  directors to be elected  multiplied  by the number of Common  Shares  owned.
Shareholders may not cumulate votes unless at least one shareholder gives notice
of his or her  intention to cumulate  votes at the Meeting.  The enclosed  proxy
confers discretionary authority to cumulate votes.

        Any shareholder giving a proxy has the power to revoke that proxy at any
time before it is voted.  A proxy may be revoked by filing with the Secretary of
the Company either a written

                                        1

<PAGE>



revocation or a duly executed proxy bearing a date subsequent to the date of the
proxy being revoked, or by voting in person at the meeting.  Any shareholder may
attend the  Meeting  and vote in person,  whether  or not such  shareholder  has
previously  submitted a proxy,  but  attendance at the Meeting will not revoke a
proxy unless the shareholder votes in person.

        The Company  will bear all of the costs of the  solicitation  of proxies
for use at the  Meeting.  In  addition  to the use of the mails,  proxies may be
solicited by a personal interview, telephone and telegram by directors, officers
and  employees  of the  Company,  who will  undertake  such  activities  without
additional  compensation.   Banks,  brokerage  houses  and  other  institutions,
nominees or fiduciaries  will be requested to forward the proxy materials to the
beneficial  owners of the  Common  Shares  held of record  by such  persons  and
entities  and will be  reimbursed  for  their  reasonable  expense  incurred  in
connection with forwarding such material.

        This Proxy Statement and the accompanying  form of proxy are first being
sent or given to the Company's shareholders on or about April 23, 1997.


                              ELECTION OF DIRECTORS


        At the  Meeting,  seven  directors  will be elected to hold office for a
one-year  term until the 1997 Annual  Meeting of  Shareholders,  and until their
successors have been duly elected and qualified. All of the nominees named below
are incumbent directors. Since the last Annual Meeting of Shareholders, Lawrence
Cohen  retired from the Board of  Directors.  The Board would like to extend its
thanks to Mr. Cohen for his years of dedicated, hard work. Jeffrey B. Nickel has
been  appointed  to the Board of  Directors  to fill the vacancy  created by the
retirement of Mr.  Cohen.  Dr.  Nickel has served as a product  development  and
marketing  consultant  to the  Company for more than two years and will bring to
the Board nearly 25 years of experience in the pharmaceutical industry.

        It is the intention of the persons named in the enclosed  proxy,  unless
such proxy specifies otherwise, to vote the shares represented by such proxy FOR
the  election of the  nominees  listed  below.  In the  unlikely  event that any
nominee  should be unable to serve as a director,  proxies may be voted in favor
of a substitute nominee designated by the Board of Directors.

Directors and Nominees

        Paul Segall,  Ph.D.,  54, is  Chairman,  President  and Chief  Executive
Officer of BioTime and has served as a director of the  Company  since 1990.  He
was a research scientist for Cryomedical Sciences, Inc. ("CMSI") and a member of
its Board of  Directors  from 1987 to  December  1990,  serving as  Director  of
Research and Vice President of Research for CMSI, from

                                        2

<PAGE>



April 1988 until  1989.  Dr.  Segall  received a Ph.D.  in  Physiology  from the
University of California at Berkeley in 1977.
   
        Ronald S. Barkin, 51, has been Executive Vice President of BioTime since
April 1997,  and has been a director of the Company since 1990. Mr. Barkin is an
attorney who has practiced civil and corporate law and has been a negotiator for
over 25 years and is an active member of the California Bar. Mr. Barkin has most
recently concluded  negotiatinos with Abbott  Laboratories on behalf of BioTime.
Mr. Barkin received a Juris Doctorate from Boalt Hall,  University of California
at Berkeley in 1970.
    
        Victoria  Bellport,  31, is Chief  Financial  Officer and Executive Vice
President  of BioTime  and has been a director of the  Company  since 1990.  Ms.
Bellport  received a B.A. in  Biochemistry  from the University of California at
Berkeley in 1988.

        Hal Sternberg,  Ph.D.,  43, is Vice President of Research of BioTime and
has been a director of the Company since 1990.  He was a research  scientist for
CMSI from 1987 to December 1990,  serving as Vice President of Biochemistry  for
CMSI from November  1987 to 1989.  Dr.  Sternberg  was a visiting  scientist and
research  Associate at the University of California at Berkeley from  1985-1988,
where he supervised a team of  researchers  studying  Alzheimer's  Disease.  Dr.
Sternberg  received his Ph.D. from the University of Maryland in Biochemistry in
1982.

        Harold Waitz, Ph.D., 54, is Vice President of Engineering of BioTime and
has been a director of the Company since 1990.  He was a research  scientist for
CMSI from 1987 to December  1990,  serving as Vice  President of Technology  for
CMSI from  November  1987 to 1989.  From  1986-1988,  Dr.  Waitz  served as Vice
President of Research at the Winters Institute, a non-profit biomedical research
institution,  at which  Dr.  Waitz  studied  arteriosclerosis  in  primates.  He
received his Ph.D.  in  Biophysics  and Medical  Physics from the  University of
California at Berkeley in 1983.


        Judith  Segall,  42, has been Vice President of Technology and Secretary
of BioTime  since 1990 and was a director of the Company from 1990 through 1994,
and from 1995 through the present  date.  She  performed  services on a contract
basis as a biochemist for CMSI during 1989, until the formation of BioTime.  Ms.
Segall  received a B.S. in Nutrition and Clinical  Dietetics from the University
of California at Berkeley in 1989.

        Jeffrey B. Nickel,  Ph.D., 53, is President of Nickel Consulting through
which he has served as a  consultant  to  companies  in the  pharmaceutical  and
biotechnology  industries since 1990. Prior to starting his consulting business,
Dr. Nickel served in a number of management positions for Syntex Corporation and
Merck & Company. Dr. Nickel received his Ph.D. in Organic Chemistry from Rutgers
University in 1970.


                                        3

<PAGE>



Executive Officers

        Paul Segall, Ronald S. Barkin, Victoria Bellport, Hal Sternberg,  Harold
Waitz and Judith Segall are the only executive officers of BioTime.

        There are no family relationships among the directors or officers of the
Company, except that Paul Segall and Judith Segall are husband and wife.


Directors' Meetings, Compensation and Committees of the Board

        The  Board  of  Directors  does  not have a  standing  Audit  Committee,
Compensation  Committee,  or  Nominating  Committee.  Nominees  to the  Board of
Directors are selected by the entire Board.

        The Board of Directors has a Stock Option Committee that administers the
Company's  1992 Stock Option Plan and makes grants of options to key  employees,
consultants,  scientific  advisory board members and independent  contractors of
the Company, but not to officers or directors of the Company. The members of the
Stock Option Committee are Paul Segall, Ronald S. Barkin, and Victoria Bellport.
The Stock Option Committee was formed during September 1992.

        During the fiscal year ended June 30, 1996,  the Board of Directors  met
three times. No director attended fewer than 75% of the meetings of the Board or
any committee on which they served.

        Directors of the Company who are not employees  receive an annual fee of
$20,000.  Directors  of the Company and  members of  committees  of the Board of
Directors  who are employees of the Company are not  compensated  for serving as
directors  or  attending  meetings  of the  Board or  committees  of the  Board.
Directors  are  entitled  to  reimbursements  for their  out-of-pocket  expenses
incurred  in  attending  meetings  of the  Board  or  committees  of the  Board.
Directors  who are  employees  of the  Company  are  also  entitled  to  receive
compensation in such capacity.

Executive Compensation

        None of the Company's executive officers received  compensation from the
Company in excess of $100,000  during the fiscal year ended June 30,  1996.  The
Company has entered into a new five-year  employment  agreement (the "Employment
Agreement") with Paul Segall,  the President and Chief Executive  Officer of the
Company.  The  Employment  Agreement  will expire on  December  31, 2000 but may
terminate  prior to the end of the term if Dr.  Segall (1) dies,  (2) leaves the
Company,  (3) becomes disabled for a period of 90 days in any 150 day period, or
(4) is  discharged  by the  Board of  Directors  for  failure  to carry  out the
reasonable policies of the Board, persistent  absenteeism,  or a material breach
of a covenant. Under his Employment

                                        4

<PAGE>



Agreement,  Dr. Segall is presently  receiving an annual salary of $85,000.  Dr.
Segall will receive a one-time cash bonus of $25,000 if the Company  receives at
least $1,000,000 of equity financing from a pharmaceutical  company.  Dr. Segall
will be entitled to seek a modification of his Employment  Agreement  before the
expiration  of  the  five  year  term  if the  market  value  of  the  Company's
outstanding capital stock exceeds $75,000,000.

        In the event of Dr.  Segall's  death  during the term of his  Employment
Agreement,  the Company will pay his estate his salary for a period of six month
or until  December  31,  2000,  whichever  first  occurs.  In the event that Dr.
Segall's employment terminates,  voluntarily or involuntarily, after a change in
control of the Company through an acquisition of voting stock, an acquisition of
the Company's  assets,  or a merger or consolidation of the Company with another
corporation  or entity,  Dr.  Segall will be entitled to severance  compensation
equal to the greater of (a) 2.99 times his average annual  compensation  for the
preceding  five years and (b) the balance of his base  salary for the  unexpired
portion of the term of his Employment Agreement.

        The Board of Directors  has also  approved  employment  agreements  that
contain the same or similar change of control  severance  benefits for the other
executive officers of the Company.

        Dr. Segall has also executed an  Intellectual  Property  Agreement which
provides that the Company is the owner of all inventions developed by Dr. Segall
during the course of his employment.

        The  following  table  summarizes  certain  information  concerning  the
compensation paid to Dr. Segall during the last three fiscal years.

<TABLE>

                           SUMMARY COMPENSATION TABLE


<CAPTION>

                                         Annual Compensation                     Long-Term
Name                                     -------------------                    Compensation
and Principal                                                                   -------------
Position                  Year             Salary($)             Bonus          Stock Options
- ---------------           ----             ---------             -----          -------------
<S>                       <C>              <C>                   <C>            <C>
Paul Segall               1996              $76,041
Chief Executive           1995              $67,500
Officer                   1994              $63,796              $25,000

</TABLE>


                                        5

<PAGE>



Stock Option Plan

        During 1992, the Company  adopted the 1992 Stock Option Plan and granted
to Paul Segall options to purchase 21,000 Common Shares at $9.22 per share.  The
options  granted to Dr.  Segall  will expire five years after the date of grant,
and will become exercisable in three equal annual installments.  No options were
granted to any of the Company's executive officers during the last fiscal year.

        The  following  table  provides  information  with respect to Dr. Segall
concerning the exercise of options  during the last fiscal year and  unexercised
options held as of June 30, 1996.

<TABLE>
                Aggregated Options Exercised in Last Fiscal Year,
                        and Fiscal Year-End Option Values

<CAPTION>

                        Number of                               Number of                     Value of Unexercised
                         Shares                           Unexercised Options at            In-the-Money Options at
                        Acquired       Value                  June 30, 1996                   June 30, 1996(1)
                           on         Realized          ---------------------------        ---------------------------
Name                    Exercise         ($)            Exercisable   Unexercisable        Exercisable   Unexercisable
- ----                   ----------       -----           -----------   -------------        -----------   -------------
<S>                    <C>              <C>             <C>           <C>                  <C>           <C>
Paul Segall                 0            --               21,000            0                $239,610           0

<FN>
(1)  Based  on the  average  of the high and low bid  prices  of a Common  Share
($20.63) as reported on the Nasdaq Small Cap Market System on such date.
</FN>
</TABLE>


Certain Relationships and Related Transactions

        During  the  twelve  months  ended  June 30,  1996,  $19,940 in fees for
consulting  services  was paid to  Ronald S.  Barkin,  and  $36,000  in fees for
consulting  services was paid to Dr. Jeffrey B. Nickel,  members of the Board of
Directors.


                                        6

<PAGE>


                             PRINCIPAL SHAREHOLDERS

        The  following  table  sets  forth  information  as  of  April  7,  1997
concerning  beneficial  ownership of Common Shares by each shareholder  known by
the Company to be the  beneficial  owner of 5% or more of the  Company's  Common
Shares,  and  the  Company's  executive  officers  and  directors.   Information
concerning  certain  beneficial  owners of more than 5% of the Common  Shares is
based upon  information  disclosed  by such owners in their  reports on Schedule
13D.

                                               Number of         Percent of
                                                Shares              Total
                                               ---------         ----------
   
Alfred D. Kingsley (1)                          362,750             11.1%
Gary K. Duberstein
Greenbelt Corp.
Greenway Partners, L.P.
Greenhouse Partners, L.P.
  277 Park Avenue, 27th Floor
  New York, New York 10017
    
WisdomTree Associates, L.P. (2)                 259,200              8.1
WisdomTree Capital Management, Inc.
  1633 Broadway, 38th Floor
  New York, New York 10019
WisdomTree Offshore, Ltd. (2)
  Zephyr House, 5th Floor
  P.O. Box 1561
  Mary Street
  Grand Cayman, Cayman Islands
  British West Indies
   
Paul and Judith Segall (3)                      236,638              7.3
    
Harold D. Waitz (4)                             167,069              5.2
   
Hal Sternberg (5)                               158,379              4.9
    
Victoria Bellport                                65,389              2.0

Ronald S. Barkin (6)                             63,337              2.0

Jeffrey B. Nickel                                 --                 --



                                        7

<PAGE>


   
All officers and directors
as a group (7 persons)(7)                        690,812             20.9
- ---------------------------
    
(1)      Includes  250,000  Common Shares  issuable upon the exercise of certain
warrants owned  beneficially by Greenbelt Corp. Mr. Kingsley and Mr.  Duberstein
may be deemed to  beneficially  own the  warrant  shares  that  Greenbelt  Corp.
beneficially  owns.  Includes  27,500 Common Shares owned by Greenway  Partners,
L.P. Greenhouse Partners, L.P. is the general partner of Greenway Partners, L.P.
and Mr.  Kingsley  and Mr.  Duberstein  are the general  partners of  Greenhouse
Partners, L.P. Greenhouse Partners, L.P., Mr. Kingsley and Mr. Duberstein may be
deemed to  beneficially  own the Common  Shares  that  Greenway  Partners,  L.P.
beneficially  owns.  Includes 81,950 Common Shares owned solely by Mr. Kingsley,
as to which Mr. Duberstein disclaims beneficial ownership. Includes 3,300 Common
Shares  owned  solely  by Mr.  Duberstein,  as to which Mr.  Kingsley  disclaims
beneficial ownership.

(2)      Includes 229,200 Common Shares owned by WisdomTree Associates, L.P. and
30,000 Common  Shares owned by  WisdomTree  Offshore,  Ltd.  WisdomTree  Capital
Management,  Inc. is the general partner of WisdomTree  Associates,  L.P. and is
the investment manager of WisdomTree Offshore, Ltd.
   
(3)      Includes 151,559 shares held of record by Paul Segall and 64,179 shares
held of record by Judith Segall. Includes 21,000 Common Shares issuable upon the
exercise of certain options.
    
(4)      Includes  21,000  Common  Shares  issuable upon the exercise of certain
options.

(5)      Includes  21,000  Common  Shares  issuable upon the exercise of certain
options.

(6)      Includes  45,000  Common  Shares  issuable upon the exercise of certain
options.

(7)      Includes  108,000  Common Shares  issuable upon the exercise of certain
options.


      COMPLIANCE WITH SECTION 16(a) OF THE SECURITIES EXCHANGE ACT OF 1934

        Section  16(a) of the  Securities  Exchange Act of 1934, as amended (the
"Exchange  Act"),  requires the Company's  directors and executive  officers and
persons  who own  more  than ten  percent  (10%)  of a  registered  class of the
Company's equity securities to file with the Securities and Exchange  Commission
(the "SEC") initial  reports of ownership and reports of changes in ownership of
Common Shares and other equity  securities of the Company.  Officers,  directors
and greater than ten percent beneficial owners are required by SEC regulation to
furnish the Company with copies of all reports they file under Section 16(a).

        To the Company's knowledge,  based solely on its review of the copies of
such reports furnished

                                        8

<PAGE>



to the Company and written  representations that no other reports were required,
all Section 16(a) filing requirements applicable to its officers,  directors and
greater than ten percent  beneficial owners were complied with during the fiscal
year ended June 30, 1996.


                     AMENDMENT OF THE 1992 STOCK OPTION PLAN


        The Board of Directors  proposes and  recommends  that the  shareholders
approve an amendment to the Company's  1992 Stock Option Plan (the "Plan") which
will make an additional  200,000  Common Shares  available for issuance upon the
exercise of options that may be granted under the Plan. The Plan currently makes
available a total of 400,000 Common Shares for which options may be granted.  As
of April 7, 1997,  the Company had  granted  options to purchase  348,000 of the
Common Shares available under the Plan, of which 103,000 have been exercised and
245,000  remain  outstanding.  The Board of  Directors  has no  present  plan or
commitment to grant any additional  options to the present executive officers of
the Company,  but the Board  strongly  believes  that the  Company's  ability to
attract and retain the  services of new  employees  and  consultants  depends in
great  measure  upon its  ability to  provide  the kind of  incentives  that are
derived from the ownership of stock options.  The Board believes that unless the
proposed amendment to the Plan is approved by the shareholders, the Company will
be placed at a serious competitive  disadvantage in attracting capable employees
and consultants at a critical time in its development.

        At April 7, 1997,  the total market value of the 297,000  Common  Shares
reserved for issuance under the Plan was  approximately  $9,207,000,  based upon
the last sale  price on such date on the  Nasdaq  Small Cap  Market.  That total
market value would increase to approximately  $15,407,000 as of April 7, 1997 if
the shareholders  approve the proposed amendment reserving an additional 200,000
Common Shares.

        The Plan is  administered  by the Board of  Directors  which  determines
which officers,  directors,  employees,  consultants,  scientific advisory board
members and  independent  contractors of the Company are to be granted  options,
the number of shares subject to the options  granted,  the exercise price of the
options, and certain other terms and conditions of the options. The Stock Option
Committee  (the  "Committee")  of the Board may grant  options under the Plan to
eligible persons other than officers and directors of the Company.

        The options  exercise  price may be payable in cash or in Common  Shares
having a fair market value equal to the exercise  price,  or in a combination of
cash and Common  Shares.  No options may be granted under the Plan more than ten
years  after the date the Plan was  adopted  by the Board of  Directors,  and no
options  granted  under the Plan may be exercised  after the  expiration  of ten
years from the date of grant.

        Options granted under the Plan may be either  "incentive  stock options"
within the meaning of Section  422(b) of the Internal  Revenue Code of 1986,  as
amended (the "Code"), or non-qualified stock

                                        9

<PAGE>



options. Incentive stock options may be granted only to employees of the Company
or its subsidiaries. The exercise price of incentive stock options granted under
the Plan must be equal to the fair market of the Company's  Common Shares on the
date the  option is  granted.  In the case of an  optionee  who,  at the time of
grant,  owns more than 10% of the combined  voting power of all classes of stock
of the Company,  the  exercise  price of any  incentive  stock option must be at
least 110% of the fair market value of the Common Shares on the grant date,  and
the term of the option may be no longer  than five  years.  The  aggregate  fair
market  value of the  Common  Shares  (determined  as of the  grant  date of the
option) with respect to which incentive stock options become exercisable for the
first time by an optionee in any calendar year may not exceed $100,000.

        Options  granted under the Plan are  nontransferable  (except by will or
the laws of descent and  distribution)  and may vest in annual  installments  or
upon the occurrence of certain events.  Incentive stock options may be exercised
only  during  employment  or  within  three  months  after  termination  of such
employment,  subject  to  certain  exceptions  in  the  event  of the  death  or
disability of the optionee.

        The  number of Common  Shares  covered  by the Plan,  and the  number of
Common Shares and exercise price per share of each outstanding option,  shall be
proportionately  adjusted  for any  increase or decrease in the number of issued
and outstanding  Common Shares  resulting from a subdivision or consolidation of
shares or the payment of a stock dividend,  or any other increase or decrease in
the number of issued and outstanding  Common Shares effected  without receipt of
consideration by the Company.

        In the event of the dissolution or liquidation of the Company, or in the
event of a reorganization, merger or consolidation of the Company as a result of
which the Common  Shares are changed into or  exchanged  for cash or property or
securities not of the Company's issue, or upon a sale of  substantially  all the
property of the Company to, or the acquisition of stock  representing  more than
eighty  percent  80% of the  voting  power  of the  stock  of the  Company  then
outstanding by, another  corporation or person, the Plan and all options granted
under the Plan  shall  terminate,  unless  provision  can be made in  writing in
connection  with such  transaction for either the continuance of the Plan and/or
for the assumption of options  granted under the Plan, or the  substitution  for
such  options by options  covering  the stock of a successor  corporation,  or a
parent or a subsidiary of a successor corporation,  with appropriate adjustments
as to the number and kind of shares and prices.

        The approval of the amendment of the Plan requires the affirmative  vote
of the  holders of a majority  of the Common  Shares  present  and voting at the
Meeting.

               The Board of Directors Recommends A Vote "FOR" the
                      Approval of the Amendment to the Plan



                                       10

<PAGE>



Federal Income Tax Consequence of Participation in the Plan

        The  following   discussion   summarizes   certain  federal  income  tax
consequences of  participation  in the Plan.  Although the Company  believes the
following  statements  are correct based on existing  provisions of the Code and
the regulations thereunder,  the Code or regulations may be amended from time to
time,  and  future  judicial  interpretations  may effect  the  veracity  of the
discussion.

        Under Section 422(a) of the Code, the grant and exercise of an incentive
stock option  pursuant to the Plan is entitled to the benefits of Section 421(a)
of the Code. Under Section 421(a), an optionee will not be required to recognize
income at the time the option is granted or at the time the option is exercised.
If the applicable  holding  periods  described below are met, when the shares of
stock received upon exercise of an incentive  stock option are sold or otherwise
disposed  of  in  a  taxable  transaction,  the  option  holder  will  recognize
compensation  income (taxed as ordinary  income),  for the taxable year in which
disposition occurs, in an amount equal to the excess of the fair market value of
the Common Shares at the time of such  disposition  over the amount paid for the
shares.

        The Company will not be entitled to any business expense  deduction with
respect  to the  grant or  exercise  of an  incentive  stock  option,  except in
connection  with a disqualifying  disposition as discussed  below. No portion of
the amount  received by the  optionee  upon the sale of Common  Shares  acquired
through the exercise of an incentive stock option will be subject to withholding
for  federal  income  taxes,  or be subject to FICA or state  disability  taxes,
except in connection with a disqualifying disposition.

        In order for a  participant  to  receive  the  favorable  tax  treatment
provided  in  Section  421(a)  of  the  Code,  Section  422  requires  that  the
participant  make no  disposition of the option shares within two years from the
date the option was  granted,  nor within one year from the date such option was
exercised and the shares were transferred to the participant.  In addition,  the
participant  must,  with  certain  exceptions  for  death or  disability,  be an
employee of the Company (or of a parent or subsidiary of the Company, as defined
in Section 424(e) and (f) of the Code, or a corporation, or parent or subsidiary
thereof,  issuing  or  assuming  the  option  in a  merger  or  other  corporate
reorganization  transaction  to which Section 424(a) of the Code applies) at all
times  within  the period  beginning  on the date of the grant of the option and
ending on a date within three months  before the date of exercise.  In the event
of the  death of the  participant,  the  holding  periods  will  not  apply to a
disposition  of the option or option  shares by the  participant's  estate or by
persons  receiving  the  option or shares  under  the  participant's  will or by
intestate succession.

        If a participant  disposes of stock acquired pursuant to the exercise of
an  incentive   stock  option  before  the  expiration  of  the  holding  period
requirements set forth above,  the participant will realize,  at the time of the
disposition,  ordinary  income to the extent the fair market value of the Common
Shares on the date the shares were purchased  exceeded the purchase  price.  The
difference  between the fair market  value of the Common  Shares on the date the
shares  were  purchased  and the amount  realized on  disposition  is treated as
long-term or  short-term  capital gain or loss,  depending on the  participant's
holding period of the Common Shares.  The amount treated as ordinary  income may
be  subject  to the income  tax  withholding  requirements  of the Code and FICA
withholding requirements. The participant

                                       11

<PAGE>



will be required to reimburse the Company,  either  directly or through  payroll
deduction,  for all  withholding  taxes that the  Company is  required to pay on
behalf of the participant.  At the time of the disposition,  the Company will be
allowed a corresponding business expense deduction under Section 162 of the Code
to the extent of the amount of the  participant's  ordinary income.  The Company
may adopt  procedures  to  assist it in  identifying  such  deductions,  and may
require a  participant  to notify the Company of his or her intention to dispose
of any such shares.

        The Plan also  permits the Company to grant  options that do not qualify
as incentive stock options.  These  "non-qualified" stock options may be granted
to  employees  or  non-employees,  such as members of the  Company's  scientific
advisory board and other persons performing  consulting or professional services
for the Company. A Plan participant who receives a non-qualified option will not
be taxed at the time of receipt of the option, provided that the option does not
have an  ascertainable  value, but the participant will be taxed at the time the
option is exercised.

        The amount of taxable  income  that will be earned  upon  exercise  of a
non-qualified option will be the difference between the fair market value of the
Common Shares on the date of the exercise and the exercise  price of the option.
The Company  will be allowed a business  expense  deduction to the extent of the
amount of the  participant's  taxable income  recognized  upon the exercise of a
non-qualified  option.  Because the option holder is subject to tax  immediately
upon  exercise of the option,  there are no applicable  holding  periods for the
stock. The option holder's tax basis in the Common Shares purchased  through the
exercise of a non-qualified  option will be equal to the exercise price paid for
the stock plus the amount of taxable  gain  recognized  upon the exercise of the
option.  The option holder may be subject to additional tax on sale of the stock
if the price realized  exceeds his or her tax basis.  The Plan is not subject to
the  provisions  of the Employee  Retirement  Income  Security  Act of 1974,  as
amended, and is not qualified under Code Section 401(a).


Options Previously Granted Under the Plan

        The  following  table  shows  certain  information   concerning  options
previously  granted under the Plan to (i) the Company's Chief Executive Officer,
(ii) all current executive officers, as a group, (iii) all current directors who
are not  executive  officers,  as a group,  (iv) each  nominee for election as a
director, (v) each other person who received 5% or more of the options, and (vi)
all employees, including all current officers who are not executive officers, as
a group:

                                                Number of Options Granted

Paul E. Segall                                           21,000
Hal Sternberg                                            21,000
Harold Waitz                                             21,000
Judith Segall                                               0
Victoria Bellport                                           0
Ronald S. Barkin                                         45,000

                                       12

<PAGE>


Jeffrey B. Nickel                                         5,000
All current executive officers, as a group               78,000
All current directors who are not executive
    officers, as a group                                  5,000
Ronald Leonardi(1)                                       30,000
Michael Powanda(1)                                       30,000
All employees, including all current officers
who are not executive officers, as a group               17,000
- ---------------------------
(1)      Dr.  Leonardi and Dr.  Powanda are  consultants  who provide advice and
assistance  to the Company in regulatory  (FDA) affairs and product  development
matters.



          AMENDMENT OF ARTICLES OF INCORPORATION TO INCREASE AUTHORIZED
                             NUMBER OF COMMON SHARES


        The Board of  Directors  has  approved  an  amendment  to the  Company's
Articles of  Incorporation  to increase the number of  authorized  Common Shares
from 5,000,000  shares to  25,000,000.  The purpose of this amendment is to give
the Company the flexibility to raise additional  capital through the issuance of
additional  shares,  and to obtain and maintain the services of  consultants  by
issuing  warrants to purchase Common Shares.  Common Shares could also be issued
in connection  with the  acquisition of another  business or business  assets or
technology.  There are presently 3,203,193 Common Shares issued and outstanding.
An additional  340,000 Common Shares are reserved for issuance under outstanding
warrants, and 297,000 Common Shares are reserved for issuance under the Plan. If
the  proposed  amendment  to  the  Plan  is  approved  by the  shareholders,  an
additional  200,000  Common Shares will be reserved for issuance under the Plan.
Accordingly,  only 1,159,807  authorized Common Shares would be available to the
Company.
   
        Although the Company has no present agreement, arrangement or commitment
to  issue  or sell  any  Common  Shares  for  cash  or in  connection  with  the
acquisition  of any  business,  assets or  technology,  the  Board of  Directors
believes that it is in the best interest of the Company and its  shareholders to
have a  sufficient  number of  authorized  but  unissued  shares  available  for
issuance in the future for such  purposes or other  opportunities  that may come
along.  Although the Company recently raised approximately  $5,600,000 through a
subscription rights offering,  additional capital will be required in the future
for the Company to complete its plans to develop and market its products.  It is
likely that the sale of Common Shares will be the  principal  means by which the
Company would raise additional capital until such time as it is able to generate
earnings sufficient to finance its operations.
    
         The   approval  of  the   amendment  of  the   Company's   Articles  of
Incorporation  requires the affirmative vote of the holders of a majority of the
issued and outstanding Common Shares.

               The Board of Directors Recommends A Vote "FOR" the
           Approval of the Amendment to the Articles of Incorporation


                                       13

<PAGE>


            RATIFICATION OF THE SELECTION OF INDEPENDENT ACCOUNTANTS

        The Board of Directors  proposes and  recommends  that the  shareholders
ratify  the  selection  of the  firm  of  Deloitte  &  Touche  LLP to  serve  as
independent accountants of the Company for the fiscal year ending June 30, 1997.
Deloitte & Touche LLP has served as the Company's independent  accountants since
1991. Unless otherwise  directed by the shareholders,  proxies will be voted FOR
approval  of the  selection  of  Deloitte  & Touche  LLP to audit the  Company's
consolidated  financial  statements.  A representative  of Deloitte & Touche LLP
will attend the Meeting,  and will have an opportunity to make a statement if he
or she so desires and may respond to appropriate questions from shareholders.

 The Board of Directors Recommends a Vote "FOR" Ratification of the Selection of
         Deloitte & Touche LLP as the Company's Independent Accountants


                            PROPOSALS OF SHAREHOLDERS


        Shareholders  of the Company who intend to present a proposal for action
at the 1997  Annual  Meeting of  Shareholders  of the  Company  must  notify the
Company's  management  of such  intention  by notice  received at the  Company's
principal executive offices not later than January 23, 1998 for such proposal to
be included in the Company's  proxy statement and form of proxy relating to such
meeting.


                                  ANNUAL REPORT


        The  Company's  Annual Report for the fiscal year ended June 30, 1996 is
being mailed to shareholders with this Proxy Statement. The Annual Report is not
to be regarded as proxy  soliciting  material.  A copy of the  Company's  Annual
Report on Form 10-K filed with the  Securities  and Exchange  Commission for the
fiscal  year  ended  June 30,  1996,  without  exhibits,  may be  obtained  by a
shareholder  without  charge,  upon  written  request  to the  Secretary  of the
Company.


                                           By Order of the Board of Directors,


                                           Paul Segall, Ph.D.
                                           President and Chief Executive Officer

   
April 23, 1997
    
                                       14

<PAGE>
                                                                      APPENDIX


                             PROXY FOR BIOTIME, INC.
                         ANNUAL MEETING OF SHAREHOLDERS

                                  May 23, 1997

                This Proxy is Solicited by the Board of Directors

        The undersigned  appoints Paul E. Segall and Ronald S. Barkin,  and each
of them, with full power of substitution,  as the undersigned's lawful agent and
proxy to attend the Annual Meeting of Shareholders  of BioTime,  Inc. on May 23,
1997 and any  adjournment  thereof and to represent  and vote all BioTime,  Inc.
Common  Shares  standing  in the name of the  undersigned  upon the books of the
corporation.

DIRECTORS RECOMMEND A VOTE "FOR" PROPOSALS NUMBERED 1, 2, 3 AND 4

1)   ELECTION OF     [] FOR all nominees listed      []  WITHHOLD AUTHORITY
     DIRECTORS              below (except as marked      to vote for all
                            to the contrary below)       nominees listed below


RONALD S. BARKIN; VICTORIA BELLPORT; JUDITH SEGALL; JEFFREY B. NICKEL;
PAUL SEGALL; HAL STERNBERG; HAROLD WAITZ

** To withhold authority to vote for any individual nominee, draw a line through
that person's name**

                                            FOR         AGAINST         ABSTAIN

2) APPROVAL OF AMENDMENT OF
      1992 STOCK OPTION PLAN                [ ]           [ ]             [ ]

3) APPROVAL OF AMENDMENT OF ARTICLES        [ ]           [ ]             [ ]
      OF INCORPORATION

4) RATIFYING APPOINTMENT OF INDEPENDENT     [ ]           [ ]             [ ]
      ACCOUNTANTS

                               The  persons named as proxy may also vote on such
                                    other  business as may properly  come before
                                    the Meeting or any adjournment thereof.


           [ ]     WISH TO ATTEND AND
                   VOTE SHARES AT MEETING


Please sign exactly as
your shares are registered.      _______________________     __________________
Persons signing as a corporate   Signature                   Date
officer or in a fiduciary
capacity should indicate their   _______________________     __________________
title or capacity.               Signature if Held Jointly   Date

                                       15




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